reg-snw-23780

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.223 2.19e-07 4.06e-02 3.10e-02
chia-screen-data-Fav-reg-snw-23780 subnetwork

Genes (24)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
MAPRE3 22924 1-1.9112.22314---
PHB 5245 82-2.7432.68936-YesYes
KIAA1551 55196 6-1.8522.36935---
ENPP7 339221 10-2.5692.3696-YesYes
VARS 7407 60-2.3662.689124TFYes-
IRGM 345611 2-1.9902.34472---
H1FX 8971 6-2.4212.36940TFYesYes
FBXO22 26263 36-1.7392.459208TF--
FOXJ3 22887 15-2.4072.36987TFYesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
UBE2T 29089 2-1.7462.22342---
REXO1 57455 12-2.3032.369130TFYes-
SVIL 6840 2-2.1442.36912-Yes-
CENPQ 55166 20-2.1372.45916-Yes-
ACTR5 79913 4-1.8872.36919---
CCT7 10574 40-2.3352.45938-Yes-
HSPD1 3329 2-1.8522.36939---
HMCN2 256158 1-2.1362.22329-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
[ APOL2 ] 23780 1-0.5642.2237---
PSPH 5723 14-2.0632.38711-Yes-

Interactions (27)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FOXJ3 22887 REXO1 57455 pd <> reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 ACTR5 79913 pd > reg.ITFP.txt: no annot
FOXJ3 22887 KIAA1551 55196 pd > reg.ITFP.txt: no annot
HSPD1 3329 FBXO22 26263 pd < reg.ITFP.txt: no annot
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
REXO1 57455 IRGM 345611 pd > reg.ITFP.txt: no annot
APOL2 23780 FBXO22 26263 pd < reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
H1FX 8971 IRGM 345611 pd > reg.ITFP.txt: no annot
SVIL 6840 REXO1 57455 pd < reg.ITFP.txt: no annot
FBXO22 26263 KIAA1551 55196 pd > reg.ITFP.txt: no annot
PSPH 5723 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
REXO1 57455 HMCN2 256158 pd > reg.ITFP.txt: no annot
REXO1 57455 ENPP7 339221 pd > reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
FBXO22 26263 CENPQ 55166 pd > reg.ITFP.txt: no annot
CCT7 10574 FBXO22 26263 pd < reg.ITFP.txt: no annot
MAPRE3 22924 REXO1 57455 pd < reg.ITFP.txt: no annot
H1FX 8971 REXO1 57455 pd <> reg.ITFP.txt: no annot
FBXO22 26263 UBE2T 29089 pd > reg.ITFP.txt: no annot
KIAA1551 55196 REXO1 57455 pd < reg.ITFP.txt: no annot
APOL2 23780 REXO1 57455 pd < reg.ITFP.txt: no annot

Related GO terms (242)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0004832valine-tRNA ligase activity2.46e-031.00e+008.668111
GO:0002842positive regulation of T cell mediated immune response to tumor cell2.46e-031.00e+008.668111
GO:0048291isotype switching to IgG isotypes2.46e-031.00e+008.668111
GO:0006438valyl-tRNA aminoacylation2.46e-031.00e+008.668111
GO:0016817hydrolase activity, acting on acid anhydrides2.46e-031.00e+008.668111
GO:0002368B cell cytokine production2.46e-031.00e+008.668111
GO:0006458'de novo' protein folding4.91e-031.00e+007.668112
GO:0048742regulation of skeletal muscle fiber development4.91e-031.00e+007.668112
GO:0006684sphingomyelin metabolic process4.91e-031.00e+007.668112
GO:0004647phosphoserine phosphatase activity4.91e-031.00e+007.668112
GO:0005846nuclear cap binding complex4.91e-031.00e+007.668112
GO:0002176male germ cell proliferation4.91e-031.00e+007.668112
GO:1903033positive regulation of microtubule plus-end binding4.91e-031.00e+007.668112
GO:0006334nucleosome assembly6.86e-031.00e+003.9962451
GO:0071437invadopodium7.36e-031.00e+007.083113
GO:0005850eukaryotic translation initiation factor 2 complex7.36e-031.00e+007.083123
GO:0003688DNA replication origin binding7.36e-031.00e+007.083113
GO:0046696lipopolysaccharide receptor complex7.36e-031.00e+007.083113
GO:0030135coated vesicle7.36e-031.00e+007.083113
GO:0006563L-serine metabolic process7.36e-031.00e+007.083113
GO:0004767sphingomyelin phosphodiesterase activity7.36e-031.00e+007.083113
GO:0045292mRNA cis splicing, via spliceosome9.80e-031.00e+006.668114
GO:0031442positive regulation of mRNA 3'-end processing9.80e-031.00e+006.668114
GO:0006290pyrimidine dimer repair9.80e-031.00e+006.668124
GO:0006564L-serine biosynthetic process9.80e-031.00e+006.668114
GO:0035519protein K29-linked ubiquitination1.22e-021.00e+006.347125
GO:0006282regulation of DNA repair1.22e-021.00e+006.347125
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.22e-021.00e+006.347125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway1.22e-021.00e+006.347115
GO:0044314protein K27-linked ubiquitination1.22e-021.00e+006.347125
GO:0002161aminoacyl-tRNA editing activity1.22e-021.00e+006.347115
GO:0051082unfolded protein binding1.26e-021.00e+003.5392570
GO:0050847progesterone receptor signaling pathway1.47e-021.00e+006.083126
GO:0085020protein K6-linked ubiquitination1.47e-021.00e+006.083126
GO:0070914UV-damage excision repair1.47e-021.00e+006.083116
GO:0043032positive regulation of macrophage activation1.47e-021.00e+006.083116
GO:0008035high-density lipoprotein particle binding1.47e-021.00e+006.083116
GO:0002199zona pellucida receptor complex1.71e-021.00e+005.861147
GO:0000731DNA synthesis involved in DNA repair1.71e-021.00e+005.861117
GO:0006301postreplication repair1.71e-021.00e+005.861127
GO:0000339RNA cap binding1.71e-021.00e+005.861117
GO:0005832chaperonin-containing T-complex1.71e-021.00e+005.861147
GO:0005845mRNA cap binding complex1.95e-021.00e+005.668118
GO:0006450regulation of translational fidelity1.95e-021.00e+005.668118
GO:0032727positive regulation of interferon-alpha production1.95e-021.00e+005.668118
GO:0010944negative regulation of transcription by competitive promoter binding1.95e-021.00e+005.668118
GO:0031011Ino80 complex1.95e-021.00e+005.668138
GO:0010388cullin deneddylation1.95e-021.00e+005.668148
GO:0051604protein maturation1.95e-021.00e+005.668118
GO:0005739mitochondrion2.00e-021.00e+001.626532659
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity2.19e-021.00e+005.499119
GO:0010225response to UV-C2.19e-021.00e+005.499129
GO:0006379mRNA cleavage2.19e-021.00e+005.499129
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.19e-021.00e+005.499129
GO:0071354cellular response to interleukin-62.19e-021.00e+005.499119
GO:0001530lipopolysaccharide binding2.19e-021.00e+005.499119
GO:0005095GTPase inhibitor activity2.43e-021.00e+005.3471110
GO:0042026protein refolding2.43e-021.00e+005.3471110
GO:0051131chaperone-mediated protein complex assembly2.43e-021.00e+005.3471310
GO:0060766negative regulation of androgen receptor signaling pathway2.67e-021.00e+005.2091411
GO:0008652cellular amino acid biosynthetic process2.67e-021.00e+005.2091211
GO:0008334histone mRNA metabolic process2.67e-021.00e+005.2091111
GO:0004527exonuclease activity2.91e-021.00e+005.0831412
GO:0002102podosome2.91e-021.00e+005.0831112
GO:0035371microtubule plus-end3.15e-021.00e+004.9681213
GO:0032733positive regulation of interleukin-10 production3.15e-021.00e+004.9681213
GO:0008156negative regulation of DNA replication3.15e-021.00e+004.9681113
GO:0000421autophagic vacuole membrane3.15e-021.00e+004.9681113
GO:0060135maternal process involved in female pregnancy3.39e-021.00e+004.8611314
GO:0050870positive regulation of T cell activation3.39e-021.00e+004.8611114
GO:0001891phagocytic cup3.39e-021.00e+004.8611114
GO:0016575histone deacetylation3.39e-021.00e+004.8611214
GO:0008135translation factor activity, nucleic acid binding3.63e-021.00e+004.7621415
GO:0000188inactivation of MAPK activity3.63e-021.00e+004.7621115
GO:0007339binding of sperm to zona pellucida3.63e-021.00e+004.7621415
GO:0043034costamere3.63e-021.00e+004.7621215
GO:0003887DNA-directed DNA polymerase activity3.86e-021.00e+004.6681216
GO:0042113B cell activation3.86e-021.00e+004.6681116
GO:0042100B cell proliferation4.10e-021.00e+004.5811117
GO:0006513protein monoubiquitination4.10e-021.00e+004.5811117
GO:0031667response to nutrient levels4.10e-021.00e+004.5811217
GO:0031047gene silencing by RNA4.34e-021.00e+004.4991218
GO:0033574response to testosterone4.34e-021.00e+004.4991118
GO:0006913nucleocytoplasmic transport4.81e-021.00e+004.3471220
GO:0034080CENP-A containing nucleosome assembly4.81e-021.00e+004.3471220
GO:0070979protein K11-linked ubiquitination4.81e-021.00e+004.3471320
GO:0071897DNA biosynthetic process4.81e-021.00e+004.3471220
GO:0032735positive regulation of interleukin-12 production4.81e-021.00e+004.3471120
GO:0034660ncRNA metabolic process4.81e-021.00e+004.3471120
GO:0051084'de novo' posttranslational protein folding5.28e-021.00e+004.2091422
GO:0000387spliceosomal snRNP assembly5.28e-021.00e+004.2091122
GO:0006687glycosphingolipid metabolic process5.28e-021.00e+004.2091122
GO:0006953acute-phase response5.74e-021.00e+004.0831224
GO:0005881cytoplasmic microtubule5.74e-021.00e+004.0831324
GO:00063707-methylguanosine mRNA capping5.74e-021.00e+004.0831524
GO:0008180COP9 signalosome5.74e-021.00e+004.0831624
GO:0070534protein K63-linked ubiquitination5.74e-021.00e+004.0831324
GO:0005654nucleoplasm5.82e-021.00e+001.216568876
GO:0005902microvillus5.97e-021.00e+004.0251125
GO:0009267cellular response to starvation6.21e-021.00e+003.9681126
GO:0050896response to stimulus6.44e-021.00e+003.9141127
GO:0032755positive regulation of interleukin-6 production6.44e-021.00e+003.9141127
GO:0032729positive regulation of interferon-gamma production6.67e-021.00e+003.8611128
GO:0016881acid-amino acid ligase activity6.67e-021.00e+003.8611328
GO:0006418tRNA aminoacylation for protein translation6.90e-021.00e+003.8101429
GO:0006446regulation of translational initiation6.90e-021.00e+003.8101229
GO:0004842ubiquitin-protein transferase activity7.09e-021.00e+002.185217179
GO:0030670phagocytic vesicle membrane7.13e-021.00e+003.7621130
GO:0051865protein autoubiquitination7.36e-021.00e+003.7141231
GO:0090305nucleic acid phosphodiester bond hydrolysis7.36e-021.00e+003.7141631
GO:0045111intermediate filament cytoskeleton7.36e-021.00e+003.7141331
GO:0042157lipoprotein metabolic process7.58e-021.00e+003.6681432
GO:0042110T cell activation7.81e-021.00e+003.6241233
GO:0007519skeletal muscle tissue development7.81e-021.00e+003.6241233
GO:0006869lipid transport8.04e-021.00e+003.5811234
GO:0000786nucleosome8.04e-021.00e+003.5811234
GO:0007254JNK cascade8.04e-021.00e+003.5811134
GO:0050434positive regulation of viral transcription8.27e-021.00e+003.5391535
GO:0006986response to unfolded protein8.27e-021.00e+003.5391135
GO:0031124mRNA 3'-end processing8.27e-021.00e+003.5391435
GO:0070936protein K48-linked ubiquitination8.27e-021.00e+003.5391135
GO:0044297cell body8.27e-021.00e+003.5391535
GO:0005743mitochondrial inner membrane8.37e-021.00e+002.04629197
GO:0005737cytoplasm8.52e-021.00e+000.628101272633
GO:0003743translation initiation factor activity8.72e-021.00e+003.4591837
GO:0005905coated pit8.72e-021.00e+003.4591237
GO:0006281DNA repair8.81e-021.00e+002.003224203
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process8.94e-021.00e+003.4211438
GO:0006665sphingolipid metabolic process8.94e-021.00e+003.4211138
GO:0006369termination of RNA polymerase II transcription8.94e-021.00e+003.4211538
GO:0042995cell projection9.62e-021.00e+003.3111141
GO:0000775chromosome, centromeric region9.62e-021.00e+003.3111641
GO:0003684damaged DNA binding9.62e-021.00e+003.3111141
GO:0006914autophagy1.03e-011.00e+003.2091144
GO:0030141secretory granule1.03e-011.00e+003.2091244
GO:0006406mRNA export from nucleus1.03e-011.00e+003.2091744
GO:0051087chaperone binding1.05e-011.00e+003.1771345
GO:0003725double-stranded RNA binding1.05e-011.00e+003.1771245
GO:0002039p53 binding1.05e-011.00e+003.1771445
GO:0009612response to mechanical stimulus1.07e-011.00e+003.1451246
GO:0008203cholesterol metabolic process1.09e-011.00e+003.1141247
GO:0006310DNA recombination1.16e-011.00e+003.0251850
GO:0006368transcription elongation from RNA polymerase II promoter1.20e-011.00e+002.9681852
GO:0006302double-strand break repair1.20e-011.00e+002.9681552
GO:0003723RNA binding1.22e-011.00e+001.720222247
GO:0016311dephosphorylation1.27e-011.00e+002.8871355
GO:0044822poly(A) RNA binding1.28e-011.00e+001.026445799
GO:0008584male gonad development1.31e-011.00e+002.8361157
GO:0003697single-stranded DNA binding1.31e-011.00e+002.8361457
GO:0042826histone deacetylase binding1.33e-011.00e+002.8101558
GO:0005829cytosol1.34e-011.00e+000.6727881787
GO:0005634nucleus1.38e-011.00e+000.463111583246
GO:0006464cellular protein modification process1.40e-011.00e+002.7381461
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.40e-011.00e+002.7381461
GO:0007010cytoskeleton organization1.40e-011.00e+002.7381461
GO:0010467gene expression1.41e-011.00e+001.190349535
GO:0051015actin filament binding1.44e-011.00e+002.6911263
GO:0050821protein stabilization1.46e-011.00e+002.6681364
GO:0030018Z disc1.46e-011.00e+002.6681364
GO:0008285negative regulation of cell proliferation1.47e-011.00e+001.555211277
GO:0006629lipid metabolic process1.48e-011.00e+002.6461265
GO:0003676nucleic acid binding1.50e-011.00e+002.6241466
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.52e-011.00e+002.6021167
GO:0030308negative regulation of cell growth1.59e-011.00e+002.5391370
GO:0030496midbody1.65e-011.00e+002.4791673
GO:0008289lipid binding1.65e-011.00e+002.4791473
GO:0001649osteoblast differentiation1.67e-011.00e+002.4591574
GO:0015630microtubule cytoskeleton1.69e-011.00e+002.4401575
GO:0005524ATP binding1.71e-011.00e+000.868437892
GO:0030529ribonucleoprotein complex1.83e-011.00e+002.3111582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.87e-011.00e+002.2761584
GO:0000209protein polyubiquitination2.03e-011.00e+002.1451692
GO:0006511ubiquitin-dependent protein catabolic process2.03e-011.00e+002.1451692
GO:0006260DNA replication2.07e-011.00e+002.1141994
GO:0005509calcium ion binding2.13e-011.00e+001.21329351
GO:0008017microtubule binding2.13e-011.00e+002.0691997
GO:0006457protein folding2.13e-011.00e+002.0691597
GO:0044267cellular protein metabolic process2.14e-011.00e+001.209214352
GO:0006413translational initiation2.17e-011.00e+002.0391699
GO:0016887ATPase activity2.19e-011.00e+002.02515100
GO:0034641cellular nitrogen compound metabolic process2.29e-011.00e+001.95415105
GO:0005769early endosome2.36e-011.00e+001.90013109
GO:0045893positive regulation of transcription, DNA-templated2.37e-011.00e+001.110221377
GO:0042981regulation of apoptotic process2.42e-011.00e+001.86114112
GO:0043005neuron projection2.44e-011.00e+001.84816113
GO:0000287magnesium ion binding2.48e-011.00e+001.82314115
GO:0005578proteinaceous extracellular matrix2.48e-011.00e+001.82314115
GO:0007049cell cycle2.48e-011.00e+001.82318115
GO:0006355regulation of transcription, DNA-templated2.55e-011.00e+000.772331715
GO:0006974cellular response to DNA damage stimulus2.59e-011.00e+001.750111121
GO:0000398mRNA splicing, via spliceosome2.72e-011.00e+001.668115128
GO:0016032viral process2.84e-011.00e+000.927230428
GO:0015629actin cytoskeleton2.86e-011.00e+001.58115136
GO:0031625ubiquitin protein ligase binding2.90e-011.00e+001.56017138
GO:0005759mitochondrial matrix2.91e-011.00e+001.55017139
GO:0044212transcription regulatory region DNA binding2.98e-011.00e+001.509113143
GO:0001701in utero embryonic development3.17e-011.00e+001.40217154
GO:0005874microtubule3.33e-011.00e+001.320110163
GO:0008380RNA splicing3.36e-011.00e+001.302121165
GO:0007067mitotic nuclear division3.36e-011.00e+001.30219165
GO:0016071mRNA metabolic process3.44e-011.00e+001.259110170
GO:0016020membrane3.44e-011.00e+000.4314561207
GO:0005730nucleolus3.50e-011.00e+000.4194741217
GO:0005102receptor binding3.51e-011.00e+001.22513174
GO:0006412translation3.57e-011.00e+001.193112178
GO:0006954inflammatory response3.68e-011.00e+001.13713185
GO:0016070RNA metabolic process3.73e-011.00e+001.114110188
GO:0005525GTP binding3.87e-011.00e+001.046112197
GO:0043065positive regulation of apoptotic process3.95e-011.00e+001.01017202
GO:0043234protein complex4.07e-011.00e+000.954113210
GO:0019899enzyme binding4.07e-011.00e+000.95417210
GO:0007275multicellular organismal development4.13e-011.00e+000.92719214
GO:0006200ATP catabolic process4.20e-011.00e+000.894113219
GO:0003682chromatin binding4.66e-011.00e+000.691115252
GO:0000139Golgi membrane4.86e-011.00e+000.60812267
GO:0043565sequence-specific DNA binding4.97e-011.00e+000.56518275
GO:0005925focal adhesion5.05e-011.00e+000.529114282
GO:0009986cell surface5.17e-011.00e+000.48415291
GO:0000278mitotic cell cycle5.44e-011.00e+000.374128314
GO:0045892negative regulation of transcription, DNA-templated5.48e-011.00e+000.360117317
GO:0043066negative regulation of apoptotic process5.53e-011.00e+000.33818322
GO:0006366transcription from RNA polymerase II promoter5.74e-011.00e+000.255123341
GO:0048471perinuclear region of cytoplasm5.78e-011.00e+000.242111344
GO:0042802identical protein binding5.88e-011.00e+000.201115354
GO:0005515protein binding5.99e-011.00e+00-0.019101984124
GO:0005789endoplasmic reticulum membrane6.22e-011.00e+000.07217387
GO:0044281small molecule metabolic process6.27e-011.00e+00-0.053235844
GO:0005794Golgi apparatus6.48e-011.00e+00-0.02916415
GO:0042803protein homodimerization activity6.59e-011.00e+00-0.073113428
GO:0005886plasma membrane6.63e-011.00e+00-0.1324461784
GO:0045087innate immune response6.80e-011.00e+00-0.152112452
GO:0000122negative regulation of transcription from RNA polymerase II promoter6.83e-011.00e+00-0.164129456
GO:0046872metal ion binding6.83e-011.00e+00-0.199224934
GO:0006351transcription, DNA-templated7.59e-011.00e+00-0.4032471076
GO:0005887integral component of plasma membrane7.67e-011.00e+00-0.49918575
GO:0003700sequence-specific DNA binding transcription factor activity7.72e-011.00e+00-0.516122582
GO:0007165signal transduction7.92e-011.00e+00-0.603124618
GO:0070062extracellular vesicular exosome7.94e-011.00e+00-0.4273511641
GO:0005615extracellular space8.09e-011.00e+00-0.678115651
GO:0005576extracellular region8.15e-011.00e+00-0.704115663
GO:0003677DNA binding9.14e-011.00e+00-1.219152947
GO:0016021integral component of membrane9.83e-011.00e+00-1.9071191526