reg-snw-23279

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.387	2.90e-08	1.33e-02	1.12e-02

chia-screen-data-Fav-reg-snw-23279 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
CENPQ	55166	20	-2.137	2.459	16	-	Yes	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
MCPH1	79648	1	-1.924	2.387	10	TF	-	-
[ NUP160 ]	23279	3	-1.529	2.387	50	-	-	-
POLH	5429	36	-2.586	2.459	24	-	Yes	Yes
FBXO22	26263	36	-1.739	2.459	208	TF	-	-
PSPH	5723	14	-2.063	2.387	11	-	Yes	-

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
FBXO22	26263	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
CCT7	10574	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
NCBP1	4686	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
PSPH	5723	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
FBXO22	26263	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
NUP160	23279	MCPH1	79648	pd	<	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
NUP160	23279	FBXO22	26263	pd	<	reg.ITFP.txt: no annot

Related GO terms (143)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004832	valine-tRNA ligase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006406	mRNA export from nucleus	1.50e-03	1.00e+00	5.094	2	7	44
GO:0048742	regulation of skeletal muscle fiber development	2.66e-03	1.00e+00	8.553	1	1	2
GO:0004647	phosphoserine phosphatase activity	2.66e-03	1.00e+00	8.553	1	1	2
GO:0005846	nuclear cap binding complex	2.66e-03	1.00e+00	8.553	1	1	2
GO:0002176	male germ cell proliferation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	3.99e-03	1.00e+00	7.968	1	2	3
GO:0006563	L-serine metabolic process	3.99e-03	1.00e+00	7.968	1	1	3
GO:0005654	nucleoplasm	4.01e-03	1.00e+00	2.100	5	68	876
GO:0005829	cytosol	4.15e-03	1.00e+00	1.557	7	88	1787
GO:0045292	mRNA cis splicing, via spliceosome	5.32e-03	1.00e+00	7.553	1	1	4
GO:0031442	positive regulation of mRNA 3'-end processing	5.32e-03	1.00e+00	7.553	1	1	4
GO:0006290	pyrimidine dimer repair	5.32e-03	1.00e+00	7.553	1	2	4
GO:0006564	L-serine biosynthetic process	5.32e-03	1.00e+00	7.553	1	1	4
GO:0006282	regulation of DNA repair	6.64e-03	1.00e+00	7.231	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.64e-03	1.00e+00	7.231	1	1	5
GO:0000278	mitotic cell cycle	7.41e-03	1.00e+00	2.843	3	28	314
GO:0050847	progesterone receptor signaling pathway	7.96e-03	1.00e+00	6.968	1	2	6
GO:0005739	mitochondrion	8.99e-03	1.00e+00	2.189	4	32	659
GO:0002199	zona pellucida receptor complex	9.28e-03	1.00e+00	6.746	1	4	7
GO:0000731	DNA synthesis involved in DNA repair	9.28e-03	1.00e+00	6.746	1	1	7
GO:0006301	postreplication repair	9.28e-03	1.00e+00	6.746	1	2	7
GO:0000339	RNA cap binding	9.28e-03	1.00e+00	6.746	1	1	7
GO:0005832	chaperonin-containing T-complex	9.28e-03	1.00e+00	6.746	1	4	7
GO:0005845	mRNA cap binding complex	1.06e-02	1.00e+00	6.553	1	1	8
GO:0006450	regulation of translational fidelity	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010388	cullin deneddylation	1.06e-02	1.00e+00	6.553	1	4	8
GO:0031080	nuclear pore outer ring	1.19e-02	1.00e+00	6.383	1	2	9
GO:0010225	response to UV-C	1.19e-02	1.00e+00	6.383	1	2	9
GO:0006379	mRNA cleavage	1.19e-02	1.00e+00	6.383	1	2	9
GO:0071354	cellular response to interleukin-6	1.19e-02	1.00e+00	6.383	1	1	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.19e-02	1.00e+00	6.383	1	2	9
GO:0005095	GTPase inhibitor activity	1.32e-02	1.00e+00	6.231	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.46e-02	1.00e+00	6.094	1	4	11
GO:0008652	cellular amino acid biosynthetic process	1.46e-02	1.00e+00	6.094	1	2	11
GO:0008334	histone mRNA metabolic process	1.46e-02	1.00e+00	6.094	1	1	11
GO:0005487	nucleocytoplasmic transporter activity	1.46e-02	1.00e+00	6.094	1	2	11
GO:0016575	histone deacetylation	1.85e-02	1.00e+00	5.746	1	2	14
GO:0008135	translation factor activity, nucleic acid binding	1.98e-02	1.00e+00	5.646	1	4	15
GO:0000188	inactivation of MAPK activity	1.98e-02	1.00e+00	5.646	1	1	15
GO:0007339	binding of sperm to zona pellucida	1.98e-02	1.00e+00	5.646	1	4	15
GO:0003887	DNA-directed DNA polymerase activity	2.11e-02	1.00e+00	5.553	1	2	16
GO:0031667	response to nutrient levels	2.24e-02	1.00e+00	5.466	1	2	17
GO:0031047	gene silencing by RNA	2.37e-02	1.00e+00	5.383	1	2	18
GO:0033574	response to testosterone	2.37e-02	1.00e+00	5.383	1	1	18
GO:0006913	nucleocytoplasmic transport	2.63e-02	1.00e+00	5.231	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	2.63e-02	1.00e+00	5.231	1	2	20
GO:0071897	DNA biosynthetic process	2.63e-02	1.00e+00	5.231	1	2	20
GO:0034660	ncRNA metabolic process	2.63e-02	1.00e+00	5.231	1	1	20
GO:0051084	'de novo' posttranslational protein folding	2.89e-02	1.00e+00	5.094	1	4	22
GO:0000387	spliceosomal snRNP assembly	2.89e-02	1.00e+00	5.094	1	1	22
GO:0010467	gene expression	3.10e-02	1.00e+00	2.075	3	49	535
GO:0006370	7-methylguanosine mRNA capping	3.15e-02	1.00e+00	4.968	1	5	24
GO:0008180	COP9 signalosome	3.15e-02	1.00e+00	4.968	1	6	24
GO:0010827	regulation of glucose transport	3.28e-02	1.00e+00	4.909	1	7	25
GO:0009267	cellular response to starvation	3.41e-02	1.00e+00	4.853	1	1	26
GO:0005737	cytoplasm	3.61e-02	1.00e+00	0.998	7	127	2633
GO:0006418	tRNA aminoacylation for protein translation	3.79e-02	1.00e+00	4.695	1	4	29
GO:0006446	regulation of translational initiation	3.79e-02	1.00e+00	4.695	1	2	29
GO:0021987	cerebral cortex development	3.92e-02	1.00e+00	4.646	1	2	30
GO:0045111	intermediate filament cytoskeleton	4.05e-02	1.00e+00	4.599	1	3	31
GO:0003723	RNA binding	4.14e-02	1.00e+00	2.605	2	22	247
GO:0007077	mitotic nuclear envelope disassembly	4.18e-02	1.00e+00	4.553	1	9	32
GO:0007254	JNK cascade	4.44e-02	1.00e+00	4.466	1	1	34
GO:0050434	positive regulation of viral transcription	4.56e-02	1.00e+00	4.424	1	5	35
GO:0031124	mRNA 3'-end processing	4.56e-02	1.00e+00	4.424	1	4	35
GO:0044297	cell body	4.56e-02	1.00e+00	4.424	1	5	35
GO:0008645	hexose transport	4.69e-02	1.00e+00	4.383	1	8	36
GO:0003743	translation initiation factor activity	4.82e-02	1.00e+00	4.344	1	8	37
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	4.95e-02	1.00e+00	4.305	1	4	38
GO:0006369	termination of RNA polymerase II transcription	4.95e-02	1.00e+00	4.305	1	5	38
GO:0000775	chromosome, centromeric region	5.33e-02	1.00e+00	4.195	1	6	41
GO:0003684	damaged DNA binding	5.33e-02	1.00e+00	4.195	1	1	41
GO:0009612	response to mechanical stimulus	5.96e-02	1.00e+00	4.029	1	2	46
GO:0015758	glucose transport	6.21e-02	1.00e+00	3.968	1	8	48
GO:0006334	nucleosome assembly	6.58e-02	1.00e+00	3.881	1	4	51
GO:0005643	nuclear pore	6.58e-02	1.00e+00	3.881	1	12	51
GO:0006368	transcription elongation from RNA polymerase II promoter	6.71e-02	1.00e+00	3.853	1	8	52
GO:0000776	kinetochore	7.08e-02	1.00e+00	3.772	1	8	55
GO:0016311	dephosphorylation	7.08e-02	1.00e+00	3.772	1	3	55
GO:0008584	male gonad development	7.33e-02	1.00e+00	3.720	1	1	57
GO:0042826	histone deacetylase binding	7.46e-02	1.00e+00	3.695	1	5	58
GO:0044267	cellular protein metabolic process	7.78e-02	1.00e+00	2.094	2	14	352
GO:0006464	cellular protein modification process	7.83e-02	1.00e+00	3.622	1	4	61
GO:0042802	identical protein binding	7.85e-02	1.00e+00	2.085	2	15	354
GO:0030018	Z disc	8.20e-02	1.00e+00	3.553	1	3	64
GO:0030308	negative regulation of cell growth	8.93e-02	1.00e+00	3.424	1	3	70
GO:0051082	unfolded protein binding	8.93e-02	1.00e+00	3.424	1	5	70
GO:0001649	osteoblast differentiation	9.42e-02	1.00e+00	3.344	1	5	74
GO:0005815	microtubule organizing center	9.79e-02	1.00e+00	3.286	1	4	77
GO:0030529	ribonucleoprotein complex	1.04e-01	1.00e+00	3.195	1	5	82
GO:0005635	nuclear envelope	1.05e-01	1.00e+00	3.178	1	6	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.06e-01	1.00e+00	3.161	1	5	84
GO:0016032	viral process	1.09e-01	1.00e+00	1.811	2	30	428
GO:0000209	protein polyubiquitination	1.16e-01	1.00e+00	3.029	1	6	92
GO:0006511	ubiquitin-dependent protein catabolic process	1.16e-01	1.00e+00	3.029	1	6	92
GO:0006260	DNA replication	1.18e-01	1.00e+00	2.998	1	9	94
GO:0006457	protein folding	1.22e-01	1.00e+00	2.953	1	5	97
GO:0006413	translational initiation	1.24e-01	1.00e+00	2.924	1	6	99
GO:0005515	protein binding	1.30e-01	1.00e+00	0.543	8	198	4124
GO:0034641	cellular nitrogen compound metabolic process	1.31e-01	1.00e+00	2.839	1	5	105
GO:0042981	regulation of apoptotic process	1.39e-01	1.00e+00	2.746	1	4	112
GO:0043005	neuron projection	1.41e-01	1.00e+00	2.733	1	6	113
GO:0000287	magnesium ion binding	1.43e-01	1.00e+00	2.707	1	4	115
GO:0007049	cell cycle	1.43e-01	1.00e+00	2.707	1	8	115
GO:0000398	mRNA splicing, via spliceosome	1.58e-01	1.00e+00	2.553	1	15	128
GO:0044212	transcription regulatory region DNA binding	1.75e-01	1.00e+00	2.393	1	13	143
GO:0001701	in utero embryonic development	1.87e-01	1.00e+00	2.286	1	7	154
GO:0005874	microtubule	1.97e-01	1.00e+00	2.204	1	10	163
GO:0008380	RNA splicing	1.99e-01	1.00e+00	2.187	1	21	165
GO:0016071	mRNA metabolic process	2.04e-01	1.00e+00	2.144	1	10	170
GO:0019221	cytokine-mediated signaling pathway	2.06e-01	1.00e+00	2.127	1	10	172
GO:0006412	translation	2.13e-01	1.00e+00	2.077	1	12	178
GO:0004842	ubiquitin-protein transferase activity	2.14e-01	1.00e+00	2.069	1	17	179
GO:0005975	carbohydrate metabolic process	2.21e-01	1.00e+00	2.014	1	10	186
GO:0016070	RNA metabolic process	2.23e-01	1.00e+00	1.998	1	10	188
GO:0005743	mitochondrial inner membrane	2.33e-01	1.00e+00	1.931	1	9	197
GO:0015031	protein transport	2.39e-01	1.00e+00	1.888	1	10	203
GO:0006281	DNA repair	2.39e-01	1.00e+00	1.888	1	24	203
GO:0019899	enzyme binding	2.46e-01	1.00e+00	1.839	1	7	210
GO:0044822	poly(A) RNA binding	2.88e-01	1.00e+00	0.911	2	45	799
GO:0044281	small molecule metabolic process	3.11e-01	1.00e+00	0.832	2	35	844
GO:0008285	negative regulation of cell proliferation	3.12e-01	1.00e+00	1.439	1	11	277
GO:0005524	ATP binding	3.36e-01	1.00e+00	0.752	2	37	892
GO:0045892	negative regulation of transcription, DNA-templated	3.49e-01	1.00e+00	1.245	1	17	317
GO:0046872	metal ion binding	3.57e-01	1.00e+00	0.686	2	24	934
GO:0055085	transmembrane transport	3.60e-01	1.00e+00	1.191	1	13	329
GO:0006366	transcription from RNA polymerase II promoter	3.70e-01	1.00e+00	1.139	1	23	341
GO:0005509	calcium ion binding	3.79e-01	1.00e+00	1.098	1	9	351
GO:0045893	positive regulation of transcription, DNA-templated	4.01e-01	1.00e+00	0.995	1	21	377
GO:0042803	protein homodimerization activity	4.42e-01	1.00e+00	0.811	1	13	428
GO:0005634	nucleus	4.45e-01	1.00e+00	0.210	5	158	3246
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.63e-01	1.00e+00	0.720	1	29	456
GO:0005730	nucleolus	4.95e-01	1.00e+00	0.304	2	74	1217
GO:0005887	integral component of plasma membrane	5.46e-01	1.00e+00	0.386	1	8	575
GO:0007165	signal transduction	5.73e-01	1.00e+00	0.282	1	24	618
GO:0006355	regulation of transcription, DNA-templated	6.28e-01	1.00e+00	0.071	1	31	715
GO:0070062	extracellular vesicular exosome	6.69e-01	1.00e+00	-0.127	2	51	1641
GO:0016020	membrane	8.20e-01	1.00e+00	-0.684	1	56	1207
GO:0005886	plasma membrane	9.28e-01	1.00e+00	-1.248	1	46	1784

chia-Fav

reg-snw-23279

Statistics

Genes (13)

Interactions (13)

Related GO terms (143)