reg-snw-22948

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.389 2.81e-08 1.30e-02 1.10e-02
chia-screen-data-Fav-reg-snw-22948 subnetwork

Genes (17)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
FOXM1 2305 9-1.6692.412210TF--
PHB 5245 82-2.7432.68936-YesYes
VARS 7407 60-2.3662.689124TFYes-
FBXO22 26263 36-1.7392.459208TF--
[ CCT5 ] 22948 1-1.4402.38941---
APLP2 334 15-2.7322.3894-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
SHFM1 7979 7-2.3662.3893-Yes-
TRAIP 10293 13-2.5462.45430TFYes-
FTSJ1 24140 43-2.4632.68935-YesYes
GPS1 2873 86-3.6212.68936TFYesYes
SMARCE1 6605 1-1.8972.3895TF--
POLH 5429 36-2.5862.45924-YesYes
SFPQ 6421 15-2.0512.389142TFYes-
FUBP1 8880 5-2.4142.38918TFYesYes

Interactions (19)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
VARS 7407 FBXO22 26263 pd <> reg.ITFP.txt: no annot
VARS 7407 CCT5 22948 pd > reg.ITFP.txt: no annot
CCT5 22948 FBXO22 26263 pd < reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
SFPQ 6421 CCT5 22948 pd > reg.ITFP.txt: no annot
FOXM1 2305 SHFM1 7979 pd > reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
FUBP1 8880 CCT5 22948 pd > reg.ITFP.txt: no annot
FOXM1 2305 CCT5 22948 pd > reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
APLP2 334 SFPQ 6421 pd < reg.ITFP.txt: no annot
SMARCE1 6605 CCT5 22948 pd > reg.ITFP.txt: no annot
FOXM1 2305 TRAIP 10293 pd <> reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
FOXM1 2305 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot

Related GO terms (202)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0004832valine-tRNA ligase activity1.74e-031.00e+009.166111
GO:0002128tRNA nucleoside ribose methylation1.74e-031.00e+009.166111
GO:0008175tRNA methyltransferase activity1.74e-031.00e+009.166111
GO:0006438valyl-tRNA aminoacylation1.74e-031.00e+009.166111
GO:0044212transcription regulatory region DNA binding1.80e-031.00e+003.591313143
GO:0045892negative regulation of transcription, DNA-templated1.85e-031.00e+002.858417317
GO:0048742regulation of skeletal muscle fiber development3.48e-031.00e+008.166112
GO:0005846nuclear cap binding complex3.48e-031.00e+008.166112
GO:0002176male germ cell proliferation3.48e-031.00e+008.166112
GO:2000781positive regulation of double-strand break repair3.48e-031.00e+008.166112
GO:0042826histone deacetylase binding4.45e-031.00e+004.3082558
GO:0005515protein binding4.45e-031.00e+000.857131984124
GO:0006281DNA repair4.85e-031.00e+003.086324203
GO:0005850eukaryotic translation initiation factor 2 complex5.21e-031.00e+007.581123
GO:1902177positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway5.21e-031.00e+007.581113
GO:0046914transition metal ion binding5.21e-031.00e+007.581113
GO:0045292mRNA cis splicing, via spliceosome6.95e-031.00e+007.166114
GO:0031442positive regulation of mRNA 3'-end processing6.95e-031.00e+007.166114
GO:0006290pyrimidine dimer repair6.95e-031.00e+007.166124
GO:0071156regulation of cell cycle arrest6.95e-031.00e+007.166124
GO:0007176regulation of epidermal growth factor-activated receptor activity6.95e-031.00e+007.166114
GO:0003723RNA binding8.36e-031.00e+002.803322247
GO:0090344negative regulation of cell aging8.68e-031.00e+006.844115
GO:0008080N-acetyltransferase activity8.68e-031.00e+006.844115
GO:0006282regulation of DNA repair8.68e-031.00e+006.844125
GO:0032873negative regulation of stress-activated MAPK cascade8.68e-031.00e+006.844115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway8.68e-031.00e+006.844115
GO:0002161aminoacyl-tRNA editing activity8.68e-031.00e+006.844115
GO:0031681G-protein beta-subunit binding8.68e-031.00e+006.844115
GO:0042382paraspeckles8.68e-031.00e+006.844135
GO:0050847progesterone receptor signaling pathway1.04e-021.00e+006.581126
GO:0002181cytoplasmic translation1.04e-021.00e+006.581116
GO:0042754negative regulation of circadian rhythm1.04e-021.00e+006.581126
GO:0046578regulation of Ras protein signal transduction1.04e-021.00e+006.581116
GO:0002199zona pellucida receptor complex1.21e-021.00e+006.359147
GO:0000731DNA synthesis involved in DNA repair1.21e-021.00e+006.359117
GO:0006301postreplication repair1.21e-021.00e+006.359127
GO:0007617mating behavior1.21e-021.00e+006.359117
GO:0000339RNA cap binding1.21e-021.00e+006.359117
GO:0005832chaperonin-containing T-complex1.21e-021.00e+006.359147
GO:0000380alternative mRNA splicing, via spliceosome1.21e-021.00e+006.359127
GO:0005730nucleolus1.35e-021.00e+001.5026741217
GO:0005845mRNA cap binding complex1.38e-021.00e+006.166118
GO:0006878cellular copper ion homeostasis1.38e-021.00e+006.166118
GO:0006450regulation of translational fidelity1.38e-021.00e+006.166118
GO:0010944negative regulation of transcription by competitive promoter binding1.38e-021.00e+006.166118
GO:0010388cullin deneddylation1.38e-021.00e+006.166148
GO:0005654nucleoplasm1.43e-021.00e+001.713568876
GO:0010225response to UV-C1.56e-021.00e+005.996129
GO:0006379mRNA cleavage1.56e-021.00e+005.996129
GO:0071354cellular response to interleukin-61.56e-021.00e+005.996119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.56e-021.00e+005.996129
GO:0032039integrator complex1.56e-021.00e+005.996119
GO:0007049cell cycle1.67e-021.00e+003.32028115
GO:0001967suckling behavior1.73e-021.00e+005.8441410
GO:0005095GTPase inhibitor activity1.73e-021.00e+005.8441110
GO:0071564npBAF complex1.73e-021.00e+005.8441310
GO:0060766negative regulation of androgen receptor signaling pathway1.90e-021.00e+005.7071411
GO:0008334histone mRNA metabolic process1.90e-021.00e+005.7071111
GO:0071565nBAF complex1.90e-021.00e+005.7071311
GO:0006366transcription from RNA polymerase II promoter1.99e-021.00e+002.337323341
GO:0006337nucleosome disassembly2.24e-021.00e+005.4661213
GO:0016514SWI/SNF complex2.24e-021.00e+005.4661313
GO:2000377regulation of reactive oxygen species metabolic process2.24e-021.00e+005.4661113
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator2.41e-021.00e+005.3591114
GO:0043393regulation of protein binding2.41e-021.00e+005.3591214
GO:0016575histone deacetylation2.41e-021.00e+005.3591214
GO:0008135translation factor activity, nucleic acid binding2.58e-021.00e+005.2591415
GO:0016922ligand-dependent nuclear receptor binding2.58e-021.00e+005.2591215
GO:0000188inactivation of MAPK activity2.58e-021.00e+005.2591115
GO:0007339binding of sperm to zona pellucida2.58e-021.00e+005.2591415
GO:0070932histone H3 deacetylation2.58e-021.00e+005.2591215
GO:0003887DNA-directed DNA polymerase activity2.75e-021.00e+005.1661216
GO:0031047gene silencing by RNA3.09e-021.00e+004.9961218
GO:0001205RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.26e-021.00e+004.9181119
GO:0008380RNA splicing3.27e-021.00e+002.800221165
GO:0043044ATP-dependent chromatin remodeling3.43e-021.00e+004.8441320
GO:0006913nucleocytoplasmic transport3.43e-021.00e+004.8441220
GO:0071897DNA biosynthetic process3.43e-021.00e+004.8441220
GO:0034660ncRNA metabolic process3.43e-021.00e+004.8441120
GO:0051084'de novo' posttranslational protein folding3.76e-021.00e+004.7071422
GO:0000387spliceosomal snRNP assembly3.76e-021.00e+004.7071122
GO:0004842ubiquitin-protein transferase activity3.79e-021.00e+002.682217179
GO:00063707-methylguanosine mRNA capping4.10e-021.00e+004.5811524
GO:0008180COP9 signalosome4.10e-021.00e+004.5811624
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.22e-021.00e+001.918329456
GO:0030901midbrain development4.27e-021.00e+004.5221125
GO:0031492nucleosomal DNA binding4.27e-021.00e+004.5221325
GO:0000976transcription regulatory region sequence-specific DNA binding4.27e-021.00e+004.5221325
GO:0009267cellular response to starvation4.43e-021.00e+004.4661126
GO:0005057receptor signaling protein activity4.43e-021.00e+004.4661226
GO:0044822poly(A) RNA binding4.48e-021.00e+001.524445799
GO:0050885neuromuscular process controlling balance4.77e-021.00e+004.3591128
GO:0000228nuclear chromosome4.77e-021.00e+004.3591228
GO:0006418tRNA aminoacylation for protein translation4.93e-021.00e+004.3081429
GO:0042752regulation of circadian rhythm4.93e-021.00e+004.3081529
GO:0006446regulation of translational initiation4.93e-021.00e+004.3081229
GO:0007254JNK cascade5.76e-021.00e+004.0781134
GO:0050434positive regulation of viral transcription5.93e-021.00e+004.0371535
GO:0031124mRNA 3'-end processing5.93e-021.00e+004.0371435
GO:0044297cell body5.93e-021.00e+004.0371535
GO:0030900forebrain development6.09e-021.00e+003.9961236
GO:0003743translation initiation factor activity6.25e-021.00e+003.9561837
GO:0010467gene expression6.27e-021.00e+001.688349535
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process6.42e-021.00e+003.9181438
GO:0006369termination of RNA polymerase II transcription6.42e-021.00e+003.9181538
GO:0048511rhythmic process6.42e-021.00e+003.9181538
GO:0003684damaged DNA binding6.91e-021.00e+003.8081141
GO:0004867serine-type endopeptidase inhibitor activity7.07e-021.00e+003.7741142
GO:0017053transcriptional repressor complex7.07e-021.00e+003.7741242
GO:0001047core promoter binding7.07e-021.00e+003.7741442
GO:0000724double-strand break repair via homologous recombination7.07e-021.00e+003.7741542
GO:0006406mRNA export from nucleus7.40e-021.00e+003.7071744
GO:0005634nucleus7.41e-021.00e+000.67191583246
GO:0001570vasculogenesis7.56e-021.00e+003.6741245
GO:0000502proteasome complex7.88e-021.00e+003.6111347
GO:0008203cholesterol metabolic process7.88e-021.00e+003.6111247
GO:0007626locomotory behavior7.88e-021.00e+003.6111147
GO:0001558regulation of cell growth8.20e-021.00e+003.5511249
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding8.20e-021.00e+003.5511449
GO:0006310DNA recombination8.36e-021.00e+003.5221850
GO:0006368transcription elongation from RNA polymerase II promoter8.68e-021.00e+003.4661852
GO:0006338chromatin remodeling9.16e-021.00e+003.3851755
GO:0008584male gonad development9.48e-021.00e+003.3331157
GO:0003697single-stranded DNA binding9.48e-021.00e+003.3331457
GO:0000785chromatin9.80e-021.00e+003.2831659
GO:0006464cellular protein modification process1.01e-011.00e+003.2351461
GO:0005739mitochondrion1.03e-011.00e+001.387332659
GO:0030018Z disc1.06e-011.00e+003.1661364
GO:0047485protein N-terminus binding1.07e-011.00e+003.1441665
GO:0030308negative regulation of cell growth1.15e-011.00e+003.0371370
GO:0051082unfolded protein binding1.15e-011.00e+003.0371570
GO:0010951negative regulation of endopeptidase activity1.17e-011.00e+003.0161271
GO:0001889liver development1.17e-011.00e+003.0161471
GO:0016363nuclear matrix1.20e-011.00e+002.97611073
GO:0051726regulation of cell cycle1.20e-011.00e+002.9761373
GO:0001649osteoblast differentiation1.21e-011.00e+002.9561574
GO:0044267cellular protein metabolic process1.24e-011.00e+001.707214352
GO:0042127regulation of cell proliferation1.31e-011.00e+002.8441480
GO:0030529ribonucleoprotein complex1.34e-011.00e+002.8081582
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.37e-011.00e+002.7741584
GO:0045893positive regulation of transcription, DNA-templated1.38e-011.00e+001.608221377
GO:0005737cytoplasm1.47e-011.00e+000.61171272633
GO:0008201heparin binding1.47e-011.00e+002.6581491
GO:0000209protein polyubiquitination1.49e-011.00e+002.6421692
GO:0006511ubiquitin-dependent protein catabolic process1.49e-011.00e+002.6421692
GO:0006260DNA replication1.52e-011.00e+002.6111994
GO:0000086G2/M transition of mitotic cell cycle1.56e-011.00e+002.5661797
GO:0006457protein folding1.56e-011.00e+002.5661597
GO:0009615response to virus1.56e-011.00e+002.5661397
GO:0006413translational initiation1.59e-011.00e+002.5371699
GO:0010628positive regulation of gene expression1.69e-011.00e+002.43812106
GO:0000790nuclear chromatin1.74e-011.00e+002.39819109
GO:0006397mRNA processing1.75e-011.00e+002.385112110
GO:0042981regulation of apoptotic process1.78e-011.00e+002.35914112
GO:0000398mRNA splicing, via spliceosome2.01e-011.00e+002.166115128
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding2.21e-011.00e+002.01617142
GO:0016874ligase activity2.26e-011.00e+001.976111146
GO:0007399nervous system development2.34e-011.00e+001.91814152
GO:0001701in utero embryonic development2.37e-011.00e+001.89917154
GO:0005874microtubule2.49e-011.00e+001.817110163
GO:0016071mRNA metabolic process2.58e-011.00e+001.757110170
GO:0000166nucleotide binding2.66e-011.00e+001.707113176
GO:0006412translation2.69e-011.00e+001.690112178
GO:0003700sequence-specific DNA binding transcription factor activity2.69e-011.00e+000.981222582
GO:0008152metabolic process2.74e-011.00e+001.65816182
GO:0003713transcription coactivator activity2.76e-011.00e+001.642121184
GO:0016567protein ubiquitination2.82e-011.00e+001.611114188
GO:0016070RNA metabolic process2.82e-011.00e+001.611110188
GO:0005743mitochondrial inner membrane2.93e-011.00e+001.54419197
GO:0007165signal transduction2.93e-011.00e+000.894224618
GO:0035556intracellular signal transduction2.96e-011.00e+001.52915199
GO:0006357regulation of transcription from RNA polymerase II promoter3.01e-011.00e+001.501114203
GO:0043234protein complex3.09e-011.00e+001.452113210
GO:0019899enzyme binding3.09e-011.00e+001.45217210
GO:0045944positive regulation of transcription from RNA polymerase II promoter3.10e-011.00e+000.835229644
GO:0005813centrosome3.18e-011.00e+001.404110217
GO:0030198extracellular matrix organization3.23e-011.00e+001.37817221
GO:0007186G-protein coupled receptor signaling pathway3.32e-011.00e+001.32714229
GO:0019901protein kinase binding3.36e-011.00e+001.30818232
GO:0008283cell proliferation3.44e-011.00e+001.26518239
GO:0006355regulation of transcription, DNA-templated3.57e-011.00e+000.684231715
GO:0003682chromatin binding3.59e-011.00e+001.189115252
GO:0005829cytosol3.80e-011.00e+000.3634881787
GO:0043565sequence-specific DNA binding3.85e-011.00e+001.06318275
GO:0008285negative regulation of cell proliferation3.87e-011.00e+001.052111277
GO:0008284positive regulation of cell proliferation3.89e-011.00e+001.04218279
GO:0000278mitotic cell cycle4.27e-011.00e+000.871128314
GO:0048471perinuclear region of cytoplasm4.57e-011.00e+000.740111344
GO:0042802identical protein binding4.66e-011.00e+000.698115354
GO:0005524ATP binding4.69e-011.00e+000.365237892
GO:0046872metal ion binding4.94e-011.00e+000.299224934
GO:0003677DNA binding5.01e-011.00e+000.279252947
GO:0006915apoptotic process5.19e-011.00e+000.483115411
GO:0016032viral process5.34e-011.00e+000.424130428
GO:0070062extracellular vesicular exosome5.63e-011.00e+000.0713511641
GO:0006351transcription, DNA-templated5.73e-011.00e+000.0942471076
GO:0016020membrane6.40e-011.00e+00-0.0712561207
GO:0005887integral component of plasma membrane6.44e-011.00e+00-0.00118575
GO:0008270zinc ion binding7.32e-011.00e+00-0.340139727
GO:0005886plasma membrane8.45e-011.00e+00-0.6352461784
GO:0016021integral component of membrane9.44e-011.00e+00-1.4101191526