reg-snw-1153

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.386	2.92e-08	1.33e-02	1.12e-02

chia-screen-data-Fav-reg-snw-1153 subnetwork

Genes (12)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
KARS	3735	12	-1.759	2.428	123	TF	-	-
MAGEH1	28986	2	-2.307	2.386	3	-	Yes	-
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
[ CIRBP ]	1153	1	-1.342	2.386	41	TF	-	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
MAPK14	1432	2	-1.902	2.386	32	-	-	-

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CIRBP	1153	KARS	3735	pd	<>	reg.ITFP.txt: no annot
CIRBP	1153	MAGEH1	28986	pd	>	reg.ITFP.txt: no annot
CIRBP	1153	SYNCRIP	10492	pd	<>	reg.ITFP.txt: no annot
CIRBP	1153	MAPK14	1432	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
KARS	3735	PHB	5245	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	KARS	3735	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot

Related GO terms (199)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	1.38e-06	1.35e-02	9.668	2	2	2
GO:0006479	protein methylation	7.57e-05	7.39e-01	7.209	2	2	11
GO:0017148	negative regulation of translation	7.16e-04	1.00e+00	5.624	2	5	33
GO:0016149	translation release factor activity, codon specific	1.23e-03	1.00e+00	9.668	1	1	1
GO:0006430	lysyl-tRNA aminoacylation	1.23e-03	1.00e+00	9.668	1	1	1
GO:0070181	small ribosomal subunit rRNA binding	1.23e-03	1.00e+00	9.668	1	1	1
GO:0038066	p38MAPK cascade	1.23e-03	1.00e+00	9.668	1	1	1
GO:0004824	lysine-tRNA ligase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	1.23e-03	1.00e+00	9.668	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0008079	translation termination factor activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	2.46e-03	1.00e+00	8.668	1	1	2
GO:0015966	diadenosine tetraphosphate biosynthetic process	2.46e-03	1.00e+00	8.668	1	1	2
GO:0008611	ether lipid biosynthetic process	2.46e-03	1.00e+00	8.668	1	1	2
GO:0006415	translational termination	2.59e-03	1.00e+00	4.691	2	2	63
GO:0005654	nucleoplasm	2.66e-03	1.00e+00	2.216	5	68	876
GO:0003723	RNA binding	2.97e-03	1.00e+00	3.305	3	22	247
GO:0010467	gene expression	3.10e-03	1.00e+00	2.605	4	49	535
GO:0001649	osteoblast differentiation	3.56e-03	1.00e+00	4.459	2	5	74
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	3.68e-03	1.00e+00	8.083	1	1	3
GO:0036123	histone H3-K9 dimethylation	3.68e-03	1.00e+00	8.083	1	1	3
GO:0090400	stress-induced premature senescence	3.68e-03	1.00e+00	8.083	1	1	3
GO:0030529	ribonucleoprotein complex	4.35e-03	1.00e+00	4.311	2	5	82
GO:0005515	protein binding	4.51e-03	1.00e+00	0.981	10	198	4124
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.56e-03	1.00e+00	4.276	2	5	84
GO:0097452	GAIT complex	4.91e-03	1.00e+00	7.668	1	2	4
GO:0006449	regulation of translational termination	4.91e-03	1.00e+00	7.668	1	1	4
GO:0006333	chromatin assembly or disassembly	4.91e-03	1.00e+00	7.668	1	1	4
GO:0036124	histone H3-K9 trimethylation	4.91e-03	1.00e+00	7.668	1	2	4
GO:0004521	endoribonuclease activity	6.13e-03	1.00e+00	7.347	1	1	5
GO:0008610	lipid biosynthetic process	6.13e-03	1.00e+00	7.347	1	1	5
GO:0006398	histone mRNA 3'-end processing	6.13e-03	1.00e+00	7.347	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.13e-03	1.00e+00	7.347	1	2	5
GO:0051525	NFAT protein binding	6.13e-03	1.00e+00	7.347	1	1	5
GO:1901741	positive regulation of myoblast fusion	6.13e-03	1.00e+00	7.347	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	6.13e-03	1.00e+00	7.347	1	1	5
GO:0030371	translation repressor activity	6.13e-03	1.00e+00	7.347	1	1	5
GO:0005739	mitochondrion	6.57e-03	1.00e+00	2.304	4	32	659
GO:0050847	progesterone receptor signaling pathway	7.35e-03	1.00e+00	7.083	1	2	6
GO:0042754	negative regulation of circadian rhythm	7.35e-03	1.00e+00	7.083	1	2	6
GO:0034063	stress granule assembly	7.35e-03	1.00e+00	7.083	1	1	6
GO:0046974	histone methyltransferase activity (H3-K9 specific)	7.35e-03	1.00e+00	7.083	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	7.35e-03	1.00e+00	7.083	1	2	6
GO:0010831	positive regulation of myotube differentiation	7.35e-03	1.00e+00	7.083	1	1	6
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	8.57e-03	1.00e+00	6.861	1	1	7
GO:0007140	male meiosis	8.57e-03	1.00e+00	6.861	1	1	7
GO:0008409	5'-3' exonuclease activity	8.57e-03	1.00e+00	6.861	1	2	7
GO:0004707	MAP kinase activity	8.57e-03	1.00e+00	6.861	1	1	7
GO:0004708	MAP kinase kinase activity	9.79e-03	1.00e+00	6.668	1	2	8
GO:0010944	negative regulation of transcription by competitive promoter binding	9.79e-03	1.00e+00	6.668	1	1	8
GO:0019395	fatty acid oxidation	9.79e-03	1.00e+00	6.668	1	1	8
GO:0071949	FAD binding	9.79e-03	1.00e+00	6.668	1	1	8
GO:0010388	cullin deneddylation	9.79e-03	1.00e+00	6.668	1	4	8
GO:0032495	response to muramyl dipeptide	9.79e-03	1.00e+00	6.668	1	1	8
GO:0000398	mRNA splicing, via spliceosome	1.03e-02	1.00e+00	3.668	2	15	128
GO:0045663	positive regulation of myoblast differentiation	1.10e-02	1.00e+00	6.499	1	2	9
GO:0006379	mRNA cleavage	1.10e-02	1.00e+00	6.499	1	2	9
GO:0048255	mRNA stabilization	1.10e-02	1.00e+00	6.499	1	1	9
GO:0071354	cellular response to interleukin-6	1.10e-02	1.00e+00	6.499	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.10e-02	1.00e+00	6.499	1	3	9
GO:0005095	GTPase inhibitor activity	1.22e-02	1.00e+00	6.347	1	1	10
GO:0008143	poly(A) binding	1.22e-02	1.00e+00	6.347	1	2	10
GO:0044822	poly(A) RNA binding	1.29e-02	1.00e+00	2.026	4	45	799
GO:0060766	negative regulation of androgen receptor signaling pathway	1.34e-02	1.00e+00	6.209	1	4	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.34e-02	1.00e+00	6.209	1	1	11
GO:0042770	signal transduction in response to DNA damage	1.34e-02	1.00e+00	6.209	1	1	11
GO:0042307	positive regulation of protein import into nucleus	1.47e-02	1.00e+00	6.083	1	3	12
GO:0051146	striated muscle cell differentiation	1.47e-02	1.00e+00	6.083	1	1	12
GO:0001502	cartilage condensation	1.59e-02	1.00e+00	5.968	1	2	13
GO:0008380	RNA splicing	1.68e-02	1.00e+00	3.302	2	21	165
GO:0016597	amino acid binding	1.71e-02	1.00e+00	5.861	1	1	14
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.71e-02	1.00e+00	5.861	1	1	14
GO:0016575	histone deacetylation	1.71e-02	1.00e+00	5.861	1	2	14
GO:0016071	mRNA metabolic process	1.77e-02	1.00e+00	3.259	2	10	170
GO:0000188	inactivation of MAPK activity	1.83e-02	1.00e+00	5.762	1	1	15
GO:0000166	nucleotide binding	1.89e-02	1.00e+00	3.209	2	13	176
GO:0048010	vascular endothelial growth factor receptor signaling pathway	1.95e-02	1.00e+00	5.668	1	1	16
GO:0005782	peroxisomal matrix	1.95e-02	1.00e+00	5.668	1	1	16
GO:0043022	ribosome binding	2.07e-02	1.00e+00	5.581	1	2	17
GO:0045648	positive regulation of erythrocyte differentiation	2.07e-02	1.00e+00	5.581	1	2	17
GO:0016070	RNA metabolic process	2.14e-02	1.00e+00	3.114	2	10	188
GO:0005737	cytoplasm	2.16e-02	1.00e+00	1.113	7	127	2633
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	2.19e-02	1.00e+00	5.499	1	2	18
GO:0030316	osteoclast differentiation	2.19e-02	1.00e+00	5.499	1	1	18
GO:0006378	mRNA polyadenylation	2.19e-02	1.00e+00	5.499	1	3	18
GO:0035924	cellular response to vascular endothelial growth factor stimulus	2.19e-02	1.00e+00	5.499	1	1	18
GO:0071346	cellular response to interferon-gamma	2.43e-02	1.00e+00	5.347	1	2	20
GO:0005720	nuclear heterochromatin	2.43e-02	1.00e+00	5.347	1	3	20
GO:0071897	DNA biosynthetic process	2.43e-02	1.00e+00	5.347	1	2	20
GO:0000077	DNA damage checkpoint	2.55e-02	1.00e+00	5.276	1	4	21
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.55e-02	1.00e+00	5.276	1	1	21
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2.55e-02	1.00e+00	5.276	1	2	21
GO:0051149	positive regulation of muscle cell differentiation	2.67e-02	1.00e+00	5.209	1	2	22
GO:0002062	chondrocyte differentiation	2.67e-02	1.00e+00	5.209	1	2	22
GO:0009409	response to cold	2.67e-02	1.00e+00	5.209	1	1	22
GO:0000049	tRNA binding	2.79e-02	1.00e+00	5.145	1	2	23
GO:0008180	COP9 signalosome	2.91e-02	1.00e+00	5.083	1	6	24
GO:0071479	cellular response to ionizing radiation	2.91e-02	1.00e+00	5.083	1	2	24
GO:0008033	tRNA processing	3.03e-02	1.00e+00	5.025	1	2	25
GO:0003730	mRNA 3'-UTR binding	3.03e-02	1.00e+00	5.025	1	1	25
GO:0000976	transcription regulatory region sequence-specific DNA binding	3.03e-02	1.00e+00	5.025	1	3	25
GO:0010494	cytoplasmic stress granule	3.15e-02	1.00e+00	4.968	1	4	26
GO:0031663	lipopolysaccharide-mediated signaling pathway	3.27e-02	1.00e+00	4.914	1	1	27
GO:0042692	muscle cell differentiation	3.39e-02	1.00e+00	4.861	1	2	28
GO:0006418	tRNA aminoacylation for protein translation	3.51e-02	1.00e+00	4.810	1	4	29
GO:0005778	peroxisomal membrane	3.51e-02	1.00e+00	4.810	1	3	29
GO:0007519	skeletal muscle tissue development	3.98e-02	1.00e+00	4.624	1	2	33
GO:0007254	JNK cascade	4.10e-02	1.00e+00	4.581	1	1	34
GO:0000902	cell morphogenesis	4.22e-02	1.00e+00	4.539	1	5	35
GO:0045727	positive regulation of translation	4.22e-02	1.00e+00	4.539	1	1	35
GO:0031124	mRNA 3'-end processing	4.22e-02	1.00e+00	4.539	1	4	35
GO:0009411	response to UV	4.34e-02	1.00e+00	4.499	1	3	36
GO:0006369	termination of RNA polymerase II transcription	4.57e-02	1.00e+00	4.421	1	5	38
GO:0048511	rhythmic process	4.57e-02	1.00e+00	4.421	1	5	38
GO:0006396	RNA processing	4.81e-02	1.00e+00	4.347	1	4	40
GO:0000775	chromosome, centromeric region	4.93e-02	1.00e+00	4.311	1	6	41
GO:0051403	stress-activated MAPK cascade	5.04e-02	1.00e+00	4.276	1	2	42
GO:0006406	mRNA export from nucleus	5.28e-02	1.00e+00	4.209	1	7	44
GO:0045892	negative regulation of transcription, DNA-templated	5.59e-02	1.00e+00	2.360	2	17	317
GO:0005777	peroxisome	5.98e-02	1.00e+00	4.025	1	2	50
GO:0034146	toll-like receptor 5 signaling pathway	5.98e-02	1.00e+00	4.025	1	3	50
GO:0034166	toll-like receptor 10 signaling pathway	5.98e-02	1.00e+00	4.025	1	3	50
GO:0018105	peptidyl-serine phosphorylation	6.09e-02	1.00e+00	3.996	1	2	51
GO:0006338	chromatin remodeling	6.56e-02	1.00e+00	3.887	1	7	55
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	6.56e-02	1.00e+00	3.887	1	3	55
GO:0034162	toll-like receptor 9 signaling pathway	6.56e-02	1.00e+00	3.887	1	3	55
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	6.56e-02	1.00e+00	3.887	1	3	55
GO:0034134	toll-like receptor 2 signaling pathway	6.67e-02	1.00e+00	3.861	1	3	56
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	6.79e-02	1.00e+00	3.836	1	2	57
GO:0042826	histone deacetylase binding	6.90e-02	1.00e+00	3.810	1	5	58
GO:0006935	chemotaxis	6.90e-02	1.00e+00	3.810	1	2	58
GO:0002756	MyD88-independent toll-like receptor signaling pathway	6.90e-02	1.00e+00	3.810	1	2	58
GO:0034138	toll-like receptor 3 signaling pathway	7.02e-02	1.00e+00	3.786	1	2	59
GO:0090090	negative regulation of canonical Wnt signaling pathway	7.02e-02	1.00e+00	3.786	1	5	59
GO:0000785	chromatin	7.02e-02	1.00e+00	3.786	1	6	59
GO:0007265	Ras protein signal transduction	7.02e-02	1.00e+00	3.786	1	3	59
GO:0071013	catalytic step 2 spliceosome	7.25e-02	1.00e+00	3.738	1	5	61
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	7.25e-02	1.00e+00	3.738	1	4	61
GO:0000187	activation of MAPK activity	7.48e-02	1.00e+00	3.691	1	3	63
GO:0071222	cellular response to lipopolysaccharide	7.59e-02	1.00e+00	3.668	1	2	64
GO:0000922	spindle pole	8.05e-02	1.00e+00	3.581	1	4	68
GO:0006928	cellular component movement	8.28e-02	1.00e+00	3.539	1	6	70
GO:0030308	negative regulation of cell growth	8.28e-02	1.00e+00	3.539	1	3	70
GO:0034142	toll-like receptor 4 signaling pathway	8.62e-02	1.00e+00	3.479	1	3	73
GO:0006915	apoptotic process	8.83e-02	1.00e+00	1.985	2	15	411
GO:0015630	microtubule cytoskeleton	8.84e-02	1.00e+00	3.440	1	5	75
GO:0071456	cellular response to hypoxia	8.95e-02	1.00e+00	3.421	1	2	76
GO:0006006	glucose metabolic process	9.40e-02	1.00e+00	3.347	1	3	80
GO:0016032	viral process	9.46e-02	1.00e+00	1.927	2	30	428
GO:0002224	toll-like receptor signaling pathway	9.74e-02	1.00e+00	3.293	1	3	83
GO:0007166	cell surface receptor signaling pathway	1.04e-01	1.00e+00	3.193	1	3	89
GO:0044255	cellular lipid metabolic process	1.04e-01	1.00e+00	3.193	1	2	89
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.05e-01	1.00e+00	1.836	2	29	456
GO:0042981	regulation of apoptotic process	1.29e-01	1.00e+00	2.861	1	4	112
GO:0007049	cell cycle	1.33e-01	1.00e+00	2.823	1	8	115
GO:0003924	GTPase activity	1.37e-01	1.00e+00	2.774	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	1.43e-01	1.00e+00	2.703	1	4	125
GO:0006184	GTP catabolic process	1.49e-01	1.00e+00	2.646	1	7	130
GO:0005759	mitochondrial matrix	1.58e-01	1.00e+00	2.550	1	7	139
GO:0030168	platelet activation	1.60e-01	1.00e+00	2.529	1	5	141
GO:0044212	transcription regulatory region DNA binding	1.62e-01	1.00e+00	2.509	1	13	143
GO:0005622	intracellular	1.64e-01	1.00e+00	2.489	1	2	145
GO:0001525	angiogenesis	1.65e-01	1.00e+00	2.479	1	2	146
GO:0007165	signal transduction	1.74e-01	1.00e+00	1.397	2	24	618
GO:0005634	nucleus	1.76e-01	1.00e+00	0.589	6	158	3246
GO:0016020	membrane	1.78e-01	1.00e+00	1.016	3	56	1207
GO:0006412	translation	1.98e-01	1.00e+00	2.193	1	12	178
GO:0005743	mitochondrial inner membrane	2.17e-01	1.00e+00	2.046	1	9	197
GO:0004674	protein serine/threonine kinase activity	2.17e-01	1.00e+00	2.046	1	8	197
GO:0005525	GTP binding	2.17e-01	1.00e+00	2.046	1	12	197
GO:0048011	neurotrophin TRK receptor signaling pathway	2.19e-01	1.00e+00	2.032	1	8	199
GO:0035556	intracellular signal transduction	2.19e-01	1.00e+00	2.032	1	5	199
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.23e-01	1.00e+00	2.003	1	14	203
GO:0030154	cell differentiation	2.24e-01	1.00e+00	1.996	1	5	204
GO:0019899	enzyme binding	2.30e-01	1.00e+00	1.954	1	7	210
GO:0043231	intracellular membrane-bounded organelle	2.37e-01	1.00e+00	1.900	1	8	218
GO:0003682	chromatin binding	2.69e-01	1.00e+00	1.691	1	15	252
GO:0008285	negative regulation of cell proliferation	2.92e-01	1.00e+00	1.555	1	11	277
GO:0005524	ATP binding	3.01e-01	1.00e+00	0.868	2	37	892
GO:0055114	oxidation-reduction process	3.19e-01	1.00e+00	1.402	1	9	308
GO:0046872	metal ion binding	3.21e-01	1.00e+00	0.801	2	24	934
GO:0007596	blood coagulation	3.46e-01	1.00e+00	1.263	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	3.47e-01	1.00e+00	1.255	1	23	341
GO:0044267	cellular protein metabolic process	3.56e-01	1.00e+00	1.209	1	14	352
GO:0045893	positive regulation of transcription, DNA-templated	3.77e-01	1.00e+00	1.110	1	21	377
GO:0005783	endoplasmic reticulum	3.80e-01	1.00e+00	1.095	1	12	381
GO:0005829	cytosol	3.81e-01	1.00e+00	0.450	3	88	1787
GO:0006351	transcription, DNA-templated	3.88e-01	1.00e+00	0.597	2	47	1076
GO:0045087	innate immune response	4.34e-01	1.00e+00	0.848	1	12	452
GO:0005887	integral component of plasma membrane	5.17e-01	1.00e+00	0.501	1	8	575
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.59e-01	1.00e+00	0.338	1	29	644
GO:0005576	extracellular region	5.70e-01	1.00e+00	0.296	1	15	663
GO:0006355	regulation of transcription, DNA-templated	5.99e-01	1.00e+00	0.187	1	31	715
GO:0008270	zinc ion binding	6.05e-01	1.00e+00	0.163	1	39	727
GO:0070062	extracellular vesicular exosome	6.24e-01	1.00e+00	-0.012	2	51	1641
GO:0044281	small molecule metabolic process	6.62e-01	1.00e+00	-0.053	1	35	844
GO:0005730	nucleolus	7.98e-01	1.00e+00	-0.581	1	74	1217
GO:0005886	plasma membrane	9.11e-01	1.00e+00	-1.132	1	46	1784

chia-Fav

reg-snw-1153

Statistics

Genes (12)

Interactions (12)

Related GO terms (199)