reg-snw-10362

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.239	1.81e-07	3.68e-02	2.82e-02

chia-screen-data-Fav-reg-snw-10362 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
FBXL6	26233	28	-2.253	2.689	22	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
PGRMC1	10857	1	-1.680	2.239	7	-	-	-
[ HMG20B ]	10362	1	-1.457	2.239	25	TF	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
GTF2A2	2958	9	-1.938	2.377	41	TF	-	-
G6PC3	92579	2	-1.713	2.239	7	-	-	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
AP2S1	1175	5	-1.558	2.367	39	-	-	-

Interactions (14)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HMG20B	10362	PGRMC1	10857	pd	>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
HMG20B	10362	G6PC3	92579	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
AP2S1	1175	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
VARS	7407	FBXL6	26233	pd	>	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
AP2S1	1175	GTF2A2	2958	pd	<	reg.ITFP.txt: no annot
AP2S1	1175	VARS	7407	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
AP2S1	1175	HMG20B	10362	pd	<	reg.ITFP.txt: no annot

Related GO terms (169)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004832	valine-tRNA ligase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0061383	trabecula morphogenesis	1.33e-03	1.00e+00	9.553	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0008175	tRNA methyltransferase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0016032	viral process	1.90e-03	1.00e+00	2.811	4	30	428
GO:0006368	transcription elongation from RNA polymerase II promoter	2.09e-03	1.00e+00	4.853	2	8	52
GO:0045666	positive regulation of neuron differentiation	2.17e-03	1.00e+00	4.825	2	3	53
GO:0033688	regulation of osteoblast proliferation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	2.66e-03	1.00e+00	8.553	1	1	2
GO:0007411	axon guidance	3.37e-03	1.00e+00	3.249	3	8	237
GO:0004346	glucose-6-phosphatase activity	3.99e-03	1.00e+00	7.968	1	1	3
GO:0015760	glucose-6-phosphate transport	3.99e-03	1.00e+00	7.968	1	1	3
GO:0005654	nucleoplasm	4.01e-03	1.00e+00	2.100	5	68	876
GO:0001649	osteoblast differentiation	4.19e-03	1.00e+00	4.344	2	5	74
GO:0010467	gene expression	4.28e-03	1.00e+00	2.490	4	49	535
GO:0036089	cleavage furrow formation	5.32e-03	1.00e+00	7.553	1	1	4
GO:0033234	negative regulation of protein sumoylation	6.64e-03	1.00e+00	7.231	1	1	5
GO:0038027	apolipoprotein A-I-mediated signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.64e-03	1.00e+00	7.231	1	2	5
GO:0043931	ossification involved in bone maturation	6.64e-03	1.00e+00	7.231	1	1	5
GO:0005672	transcription factor TFIIA complex	6.64e-03	1.00e+00	7.231	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.64e-03	1.00e+00	7.231	1	1	5
GO:0050847	progesterone receptor signaling pathway	7.96e-03	1.00e+00	6.968	1	2	6
GO:0002181	cytoplasmic translation	7.96e-03	1.00e+00	6.968	1	1	6
GO:0001055	RNA polymerase II activity	7.96e-03	1.00e+00	6.968	1	3	6
GO:0051156	glucose 6-phosphate metabolic process	7.96e-03	1.00e+00	6.968	1	1	6
GO:0043297	apical junction assembly	7.96e-03	1.00e+00	6.968	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	7.96e-03	1.00e+00	6.968	1	2	6
GO:0035615	clathrin adaptor activity	9.28e-03	1.00e+00	6.746	1	1	7
GO:0007049	cell cycle	9.85e-03	1.00e+00	3.707	2	8	115
GO:0090307	spindle assembly involved in mitosis	1.06e-02	1.00e+00	6.553	1	2	8
GO:0006450	regulation of translational fidelity	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010388	cullin deneddylation	1.06e-02	1.00e+00	6.553	1	4	8
GO:0043296	apical junction complex	1.06e-02	1.00e+00	6.553	1	1	8
GO:0030122	AP-2 adaptor complex	1.19e-02	1.00e+00	6.383	1	2	9
GO:0071354	cellular response to interleukin-6	1.19e-02	1.00e+00	6.383	1	1	9
GO:0030100	regulation of endocytosis	1.19e-02	1.00e+00	6.383	1	1	9
GO:0048268	clathrin coat assembly	1.19e-02	1.00e+00	6.383	1	2	9
GO:0072583	clathrin-mediated endocytosis	1.19e-02	1.00e+00	6.383	1	1	9
GO:0000398	mRNA splicing, via spliceosome	1.21e-02	1.00e+00	3.553	2	15	128
GO:0005736	DNA-directed RNA polymerase I complex	1.32e-02	1.00e+00	6.231	1	4	10
GO:0005095	GTPase inhibitor activity	1.32e-02	1.00e+00	6.231	1	1	10
GO:0050919	negative chemotaxis	1.32e-02	1.00e+00	6.231	1	1	10
GO:0001054	RNA polymerase I activity	1.32e-02	1.00e+00	6.231	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.46e-02	1.00e+00	6.094	1	4	11
GO:0017025	TBP-class protein binding	1.59e-02	1.00e+00	5.968	1	1	12
GO:0050772	positive regulation of axonogenesis	1.72e-02	1.00e+00	5.853	1	2	13
GO:0050770	regulation of axonogenesis	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0001056	RNA polymerase III activity	1.72e-02	1.00e+00	5.853	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.72e-02	1.00e+00	5.853	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.85e-02	1.00e+00	5.746	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.85e-02	1.00e+00	5.746	1	3	14
GO:0050771	negative regulation of axonogenesis	1.85e-02	1.00e+00	5.746	1	2	14
GO:0016575	histone deacetylation	1.85e-02	1.00e+00	5.746	1	2	14
GO:0006367	transcription initiation from RNA polymerase II promoter	1.87e-02	1.00e+00	3.222	2	18	161
GO:0008380	RNA splicing	1.96e-02	1.00e+00	3.187	2	21	165
GO:0000188	inactivation of MAPK activity	1.98e-02	1.00e+00	5.646	1	1	15
GO:0032467	positive regulation of cytokinesis	2.11e-02	1.00e+00	5.553	1	1	16
GO:0017022	myosin binding	2.11e-02	1.00e+00	5.553	1	2	16
GO:0005496	steroid binding	2.24e-02	1.00e+00	5.466	1	1	17
GO:0003899	DNA-directed RNA polymerase activity	2.37e-02	1.00e+00	5.383	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	2.50e-02	1.00e+00	5.305	1	1	19
GO:0071897	DNA biosynthetic process	2.63e-02	1.00e+00	5.231	1	2	20
GO:0048011	neurotrophin TRK receptor signaling pathway	2.78e-02	1.00e+00	2.916	2	8	199
GO:0050690	regulation of defense response to virus by virus	2.89e-02	1.00e+00	5.094	1	1	22
GO:0001103	RNA polymerase II repressing transcription factor binding	3.02e-02	1.00e+00	5.029	1	2	23
GO:0030669	clathrin-coated endocytic vesicle membrane	3.02e-02	1.00e+00	5.029	1	1	23
GO:0006370	7-methylguanosine mRNA capping	3.15e-02	1.00e+00	4.968	1	5	24
GO:0008180	COP9 signalosome	3.15e-02	1.00e+00	4.968	1	6	24
GO:0030054	cell junction	3.29e-02	1.00e+00	2.785	2	5	218
GO:0051496	positive regulation of stress fiber assembly	3.41e-02	1.00e+00	4.853	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	3.54e-02	1.00e+00	4.798	1	4	27
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.67e-02	1.00e+00	4.746	1	2	28
GO:0006418	tRNA aminoacylation for protein translation	3.79e-02	1.00e+00	4.695	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	3.79e-02	1.00e+00	4.695	1	6	29
GO:0032154	cleavage furrow	3.92e-02	1.00e+00	4.646	1	3	30
GO:0006094	gluconeogenesis	4.05e-02	1.00e+00	4.599	1	1	31
GO:0035914	skeletal muscle cell differentiation	4.31e-02	1.00e+00	4.509	1	3	33
GO:0021762	substantia nigra development	4.44e-02	1.00e+00	4.466	1	1	34
GO:0007254	JNK cascade	4.44e-02	1.00e+00	4.466	1	1	34
GO:0008565	protein transporter activity	4.56e-02	1.00e+00	4.424	1	2	35
GO:0050434	positive regulation of viral transcription	4.56e-02	1.00e+00	4.424	1	5	35
GO:0007266	Rho protein signal transduction	4.56e-02	1.00e+00	4.424	1	2	35
GO:0008645	hexose transport	4.69e-02	1.00e+00	4.383	1	8	36
GO:0030334	regulation of cell migration	4.69e-02	1.00e+00	4.383	1	2	36
GO:0030666	endocytic vesicle membrane	4.69e-02	1.00e+00	4.383	1	1	36
GO:0046982	protein heterodimerization activity	4.70e-02	1.00e+00	2.503	2	11	265
GO:0006396	RNA processing	5.20e-02	1.00e+00	4.231	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	5.20e-02	1.00e+00	4.231	1	6	40
GO:0032481	positive regulation of type I interferon production	6.21e-02	1.00e+00	3.968	1	3	48
GO:0015758	glucose transport	6.21e-02	1.00e+00	3.968	1	8	48
GO:0016020	membrane	6.65e-02	1.00e+00	1.316	4	56	1207
GO:0006289	nucleotide-excision repair	6.83e-02	1.00e+00	3.825	1	6	53
GO:0005694	chromosome	7.08e-02	1.00e+00	3.772	1	4	55
GO:0016311	dephosphorylation	7.08e-02	1.00e+00	3.772	1	3	55
GO:0007596	blood coagulation	7.28e-02	1.00e+00	2.148	2	13	339
GO:0006366	transcription from RNA polymerase II promoter	7.36e-02	1.00e+00	2.139	2	23	341
GO:0042826	histone deacetylase binding	7.46e-02	1.00e+00	3.695	1	5	58
GO:0071013	catalytic step 2 spliceosome	7.83e-02	1.00e+00	3.622	1	5	61
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	8.20e-02	1.00e+00	3.553	1	3	64
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	8.57e-02	1.00e+00	3.487	1	5	67
GO:0016568	chromatin modification	8.69e-02	1.00e+00	3.466	1	3	68
GO:0030308	negative regulation of cell growth	8.93e-02	1.00e+00	3.424	1	3	70
GO:0005789	endoplasmic reticulum membrane	9.16e-02	1.00e+00	1.957	2	7	387
GO:0030496	midbody	9.30e-02	1.00e+00	3.363	1	6	73
GO:0051056	regulation of small GTPase mediated signal transduction	9.66e-02	1.00e+00	3.305	1	2	76
GO:0005938	cell cortex	9.79e-02	1.00e+00	3.286	1	6	77
GO:0030529	ribonucleoprotein complex	1.04e-01	1.00e+00	3.195	1	5	82
GO:0005215	transporter activity	1.04e-01	1.00e+00	3.195	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	1.05e-01	1.00e+00	3.178	1	2	83
GO:0030027	lamellipodium	1.11e-01	1.00e+00	3.094	1	3	88
GO:0020037	heme binding	1.11e-01	1.00e+00	3.094	1	3	88
GO:0006886	intracellular protein transport	1.12e-01	1.00e+00	3.077	1	2	89
GO:0030036	actin cytoskeleton organization	1.13e-01	1.00e+00	3.061	1	4	90
GO:0003677	DNA binding	1.25e-01	1.00e+00	1.251	3	52	947
GO:0005515	protein binding	1.30e-01	1.00e+00	0.543	8	198	4124
GO:0007179	transforming growth factor beta receptor signaling pathway	1.34e-01	1.00e+00	2.811	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.35e-01	1.00e+00	2.798	1	2	108
GO:0042981	regulation of apoptotic process	1.39e-01	1.00e+00	2.746	1	4	112
GO:0003924	GTPase activity	1.47e-01	1.00e+00	2.658	1	7	119
GO:0006184	GTP catabolic process	1.60e-01	1.00e+00	2.531	1	7	130
GO:0030168	platelet activation	1.72e-01	1.00e+00	2.413	1	5	141
GO:0007173	epidermal growth factor receptor signaling pathway	1.73e-01	1.00e+00	2.403	1	5	142
GO:0044212	transcription regulatory region DNA binding	1.75e-01	1.00e+00	2.393	1	13	143
GO:0005829	cytosol	2.02e-01	1.00e+00	0.750	4	88	1787
GO:0007264	small GTPase mediated signal transduction	2.09e-01	1.00e+00	2.110	1	8	174
GO:0004842	ubiquitin-protein transferase activity	2.14e-01	1.00e+00	2.069	1	17	179
GO:0005730	nucleolus	2.15e-01	1.00e+00	0.889	3	74	1217
GO:0005739	mitochondrion	2.17e-01	1.00e+00	1.189	2	32	659
GO:0003713	transcription coactivator activity	2.19e-01	1.00e+00	2.029	1	21	184
GO:0005975	carbohydrate metabolic process	2.21e-01	1.00e+00	2.014	1	10	186
GO:0016567	protein ubiquitination	2.23e-01	1.00e+00	1.998	1	14	188
GO:0005856	cytoskeleton	2.26e-01	1.00e+00	1.983	1	8	190
GO:0005743	mitochondrial inner membrane	2.33e-01	1.00e+00	1.931	1	9	197
GO:0005525	GTP binding	2.33e-01	1.00e+00	1.931	1	12	197
GO:0005634	nucleus	2.39e-01	1.00e+00	0.473	6	158	3246
GO:0006281	DNA repair	2.39e-01	1.00e+00	1.888	1	24	203
GO:0008134	transcription factor binding	2.45e-01	1.00e+00	1.846	1	10	209
GO:0006355	regulation of transcription, DNA-templated	2.46e-01	1.00e+00	1.071	2	31	715
GO:0019899	enzyme binding	2.46e-01	1.00e+00	1.839	1	7	210
GO:0007268	synaptic transmission	2.50e-01	1.00e+00	1.811	1	7	214
GO:0003723	RNA binding	2.83e-01	1.00e+00	1.605	1	22	247
GO:0006508	proteolysis	3.00e-01	1.00e+00	1.509	1	11	264
GO:0008285	negative regulation of cell proliferation	3.12e-01	1.00e+00	1.439	1	11	277
GO:0005925	focal adhesion	3.17e-01	1.00e+00	1.413	1	14	282
GO:0009986	cell surface	3.25e-01	1.00e+00	1.368	1	5	291
GO:0005524	ATP binding	3.36e-01	1.00e+00	0.752	2	37	892
GO:0045892	negative regulation of transcription, DNA-templated	3.49e-01	1.00e+00	1.245	1	17	317
GO:0055085	transmembrane transport	3.60e-01	1.00e+00	1.191	1	13	329
GO:0070062	extracellular vesicular exosome	3.77e-01	1.00e+00	0.458	3	51	1641
GO:0045893	positive regulation of transcription, DNA-templated	4.01e-01	1.00e+00	0.995	1	21	377
GO:0005783	endoplasmic reticulum	4.04e-01	1.00e+00	0.979	1	12	381
GO:0042803	protein homodimerization activity	4.42e-01	1.00e+00	0.811	1	13	428
GO:0045087	innate immune response	4.60e-01	1.00e+00	0.733	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.63e-01	1.00e+00	0.720	1	29	456
GO:0005887	integral component of plasma membrane	5.46e-01	1.00e+00	0.386	1	8	575
GO:0007165	signal transduction	5.73e-01	1.00e+00	0.282	1	24	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.88e-01	1.00e+00	0.222	1	29	644
GO:0016021	integral component of membrane	6.26e-01	1.00e+00	-0.023	2	19	1526
GO:0044822	poly(A) RNA binding	6.71e-01	1.00e+00	-0.089	1	45	799
GO:0044281	small molecule metabolic process	6.91e-01	1.00e+00	-0.168	1	35	844
GO:0005886	plasma membrane	7.17e-01	1.00e+00	-0.248	2	46	1784
GO:0005737	cytoplasm	7.24e-01	1.00e+00	-0.225	3	127	2633
GO:0006351	transcription, DNA-templated	7.81e-01	1.00e+00	-0.518	1	47	1076

chia-Fav

reg-snw-10362

Statistics

Genes (13)

Interactions (14)

Related GO terms (169)