Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.870 | 6.97e-16 | 3.17e-04 | 2.51e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EMX1 | 2016 | 4 | -2.369 | 3.216 | 19 | Yes | - |
FTL | 2512 | 2 | -2.396 | 2.922 | 25 | Yes | Yes |
KDM4B | 23030 | 5 | -3.892 | 3.216 | 5 | Yes | - |
CDC42 | 998 | 9 | -2.199 | 3.119 | 265 | Yes | Yes |
NFKB1 | 4790 | 9 | -2.123 | 2.870 | 263 | Yes | - |
NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
YY1 | 7528 | 24 | -2.572 | 3.120 | 114 | Yes | Yes |
[ SPI1 ] | 6688 | 2 | -2.003 | 2.870 | 115 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
CDC42 | 998 | SPI1 | 6688 | pp | -- | int.I2D: INNATEDB_Mouse |
NFRKB | 4798 | YY1 | 7528 | pp | -- | int.I2D: BioGrid |
FTL | 2512 | SPI1 | 6688 | pp | -- | int.I2D: IntAct |
NFKB1 | 4790 | SPI1 | 6688 | pp | -- | int.I2D: HPRD, BCI; int.Ravasi: -; int.HPRD: in vitro |
NFKB1 | 4790 | YY1 | 7528 | pp | -- | int.Intact: MI:0915(physical association) |
EMX1 | 2016 | KDM4B | 23030 | pp | -- | int.I2D: BioGrid_Mouse |
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
NFKB1 | 4790 | NFRKB | 4798 | pp | -- | int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro |
SPI1 | 6688 | YY1 | 7528 | pp | -- | int.Mysickova: lymph_node |
EMX1 | 2016 | SPI1 | 6688 | pp | -- | int.I2D: BioGrid_Mouse |
POU5F1 | 5460 | SPI1 | 6688 | pp | -- | int.Mysickova: lymph_node |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0031011 | Ino80 complex | 3.14e-05 | 4.53e-01 | 7.839 | 2 | 6 | 14 |
GO:0030225 | macrophage differentiation | 3.62e-05 | 5.22e-01 | 7.739 | 2 | 2 | 15 |
GO:0006366 | transcription from RNA polymerase II promoter | 7.88e-05 | 1.00e+00 | 3.935 | 4 | 30 | 419 |
GO:0044212 | transcription regulatory region DNA binding | 1.24e-04 | 1.00e+00 | 4.839 | 3 | 17 | 168 |
GO:0035019 | somatic stem cell maintenance | 2.67e-04 | 1.00e+00 | 6.324 | 2 | 6 | 40 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 5.67e-04 | 1.00e+00 | 3.197 | 4 | 39 | 699 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 5.81e-04 | 1.00e+00 | 5.764 | 2 | 5 | 59 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0045083 | negative regulation of interleukin-12 biosynthetic process | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 9.13e-04 | 1.00e+00 | 5.437 | 2 | 4 | 74 |
GO:0034696 | response to prostaglandin F | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0008043 | intracellular ferritin complex | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0071338 | positive regulation of hair follicle cell proliferation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0090241 | negative regulation of histone H4 acetylation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 2 | 2 |
GO:0006403 | RNA localization | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0090135 | actin filament branching | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0060661 | submandibular salivary gland formation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0033256 | I-kappaB/NF-kappaB complex | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0051683 | establishment of Golgi localization | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0044027 | hypermethylation of CpG island | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0034191 | apolipoprotein A-I receptor binding | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0003161 | cardiac conduction system development | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:1900127 | positive regulation of hyaluronan biosynthetic process | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0006355 | regulation of transcription, DNA-templated | 2.16e-03 | 1.00e+00 | 2.685 | 4 | 43 | 997 |
GO:0010957 | negative regulation of vitamin D biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0032375 | negative regulation of cholesterol transport | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0045646 | regulation of erythrocyte differentiation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0032269 | negative regulation of cellular protein metabolic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:2000630 | positive regulation of miRNA metabolic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0030098 | lymphocyte differentiation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0060684 | epithelial-mesenchymal cell signaling | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0051835 | positive regulation of synapse structural plasticity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0048664 | neuron fate determination | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0072384 | organelle transport along microtubule | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0001714 | endodermal cell fate specification | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0035088 | establishment or maintenance of apical/basal cell polarity | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0021796 | cerebral cortex regionalization | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:1990138 | neuron projection extension | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0051525 | NFAT protein binding | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 5 |
GO:0036336 | dendritic cell migration | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0010884 | positive regulation of lipid storage | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0031256 | leading edge membrane | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0045347 | negative regulation of MHC class II biosynthetic process | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0060033 | anatomical structure regression | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0060789 | hair follicle placode formation | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 2 | 6 |
GO:0007097 | nuclear migration | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0002320 | lymphoid progenitor cell differentiation | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0003334 | keratinocyte development | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:1902262 | apoptotic process involved in patterning of blood vessels | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0048554 | positive regulation of metalloenzyme activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0043497 | regulation of protein heterodimerization activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 4.31e-03 | 1.00e+00 | 3.076 | 3 | 37 | 570 |
GO:0071354 | cellular response to interleukin-6 | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 2 | 7 |
GO:0051988 | regulation of attachment of spindle microtubules to kinetochore | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 2 | 7 |
GO:0045814 | negative regulation of gene expression, epigenetic | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 2 | 7 |
GO:0051489 | regulation of filopodium assembly | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 1 | 7 |
GO:0005667 | transcription factor complex | 4.98e-03 | 1.00e+00 | 4.195 | 2 | 17 | 175 |
GO:0071316 | cellular response to nicotine | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 8 |
GO:0005515 | protein binding | 5.23e-03 | 1.00e+00 | 1.090 | 8 | 198 | 6024 |
GO:0008199 | ferric iron binding | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0010225 | response to UV-C | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 2 | 9 |
GO:0090136 | epithelial cell-cell adhesion | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0000975 | regulatory region DNA binding | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 2 | 9 |
GO:0000400 | four-way junction DNA binding | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0006826 | iron ion transport | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0030851 | granulocyte differentiation | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0021895 | cerebral cortex neuron differentiation | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0035413 | positive regulation of catenin import into nucleus | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 10 |
GO:0031274 | positive regulation of pseudopodium assembly | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 10 |
GO:0060047 | heart contraction | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 10 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 4 | 11 |
GO:0035198 | miRNA binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 12 |
GO:0051213 | dioxygenase activity | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 13 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 13 |
GO:0046688 | response to copper ion | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 13 |
GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0031293 | membrane protein intracellular domain proteolysis | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0031333 | negative regulation of protein complex assembly | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0031996 | thioesterase binding | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0071375 | cellular response to peptide hormone stimulus | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 14 |
GO:0043011 | myeloid dendritic cell differentiation | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:0001824 | blastocyst development | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:0051233 | spindle midzone | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:0048854 | brain morphogenesis | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:0008134 | transcription factor binding | 9.34e-03 | 1.00e+00 | 3.727 | 2 | 18 | 242 |
GO:0042176 | regulation of protein catabolic process | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 16 |
GO:0051276 | chromosome organization | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 16 |
GO:0048593 | camera-type eye morphogenesis | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 16 |
GO:0030742 | GTP-dependent protein binding | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 1 | 17 |
GO:0090316 | positive regulation of intracellular protein transport | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 2 | 17 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.07e-02 | 1.00e+00 | 2.607 | 3 | 41 | 789 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 1.10e-02 | 1.00e+00 | 3.602 | 2 | 23 | 264 |
GO:0007088 | regulation of mitosis | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 18 |
GO:0046847 | filopodium assembly | 1.18e-02 | 1.00e+00 | 6.398 | 1 | 1 | 19 |
GO:0006954 | inflammatory response | 1.21e-02 | 1.00e+00 | 3.532 | 2 | 6 | 277 |
GO:0055072 | iron ion homeostasis | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 2 | 21 |
GO:0031435 | mitogen-activated protein kinase kinase kinase binding | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 1 | 21 |
GO:0031424 | keratinization | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 2 | 22 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 4 | 22 |
GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 3 | 23 |
GO:0002040 | sprouting angiogenesis | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 2 | 23 |
GO:0051017 | actin filament bundle assembly | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 1 | 23 |
GO:0007163 | establishment or maintenance of cell polarity | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 2 | 24 |
GO:0031519 | PcG protein complex | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 1 | 25 |
GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 26 |
GO:0045859 | regulation of protein kinase activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 26 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 26 |
GO:0051149 | positive regulation of muscle cell differentiation | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 4 | 27 |
GO:0032467 | positive regulation of cytokinesis | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 2 | 27 |
GO:0031069 | hair follicle morphogenesis | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 27 |
GO:0072686 | mitotic spindle | 1.80e-02 | 1.00e+00 | 5.788 | 1 | 3 | 29 |
GO:0003723 | RNA binding | 1.81e-02 | 1.00e+00 | 3.228 | 2 | 18 | 342 |
GO:0043565 | sequence-specific DNA binding | 1.85e-02 | 1.00e+00 | 3.212 | 2 | 11 | 346 |
GO:0034644 | cellular response to UV | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 30 |
GO:0031647 | regulation of protein stability | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 4 | 30 |
GO:0071347 | cellular response to interleukin-1 | 1.92e-02 | 1.00e+00 | 5.692 | 1 | 2 | 31 |
GO:0031072 | heat shock protein binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 33 |
GO:0001085 | RNA polymerase II transcription factor binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 33 |
GO:0005925 | focal adhesion | 2.05e-02 | 1.00e+00 | 3.130 | 2 | 9 | 366 |
GO:0042692 | muscle cell differentiation | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 4 | 34 |
GO:0034332 | adherens junction organization | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 36 |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 36 |
GO:0045740 | positive regulation of DNA replication | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 36 |
GO:0030218 | erythrocyte differentiation | 2.29e-02 | 1.00e+00 | 5.437 | 1 | 1 | 37 |
GO:0006892 | post-Golgi vesicle-mediated transport | 2.65e-02 | 1.00e+00 | 5.220 | 1 | 2 | 43 |
GO:0021762 | substantia nigra development | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 44 |
GO:0034613 | cellular protein localization | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 44 |
GO:0043966 | histone H3 acetylation | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 5 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 4 | 46 |
GO:0090263 | positive regulation of canonical Wnt signaling pathway | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 48 |
GO:0007030 | Golgi organization | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 3 | 49 |
GO:0030175 | filopodium | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 50 |
GO:0006879 | cellular iron ion homeostasis | 3.14e-02 | 1.00e+00 | 4.974 | 1 | 3 | 51 |
GO:0009611 | response to wounding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 5 | 53 |
GO:0005634 | nucleus | 3.27e-02 | 1.00e+00 | 1.077 | 6 | 159 | 4559 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.38e-02 | 1.00e+00 | 2.745 | 2 | 24 | 478 |
GO:0046330 | positive regulation of JNK cascade | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 2 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 2 | 55 |
GO:0003677 | DNA binding | 3.43e-02 | 1.00e+00 | 1.981 | 3 | 49 | 1218 |
GO:0050728 | negative regulation of inflammatory response | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 3 | 56 |
GO:0042802 | identical protein binding | 3.46e-02 | 1.00e+00 | 2.727 | 2 | 19 | 484 |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 3.62e-02 | 1.00e+00 | 4.764 | 1 | 2 | 59 |
GO:0032481 | positive regulation of type I interferon production | 3.74e-02 | 1.00e+00 | 4.715 | 1 | 6 | 61 |
GO:0003705 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity | 3.74e-02 | 1.00e+00 | 4.715 | 1 | 4 | 61 |
GO:0030141 | secretory granule | 3.80e-02 | 1.00e+00 | 4.692 | 1 | 4 | 62 |
GO:0006310 | DNA recombination | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 7 | 65 |
GO:0034146 | toll-like receptor 5 signaling pathway | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 4 | 65 |
GO:0071260 | cellular response to mechanical stimulus | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 4 | 65 |
GO:0031295 | T cell costimulation | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 1 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 4 | 65 |
GO:0035264 | multicellular organism growth | 4.11e-02 | 1.00e+00 | 4.580 | 1 | 2 | 67 |
GO:0010468 | regulation of gene expression | 4.17e-02 | 1.00e+00 | 4.559 | 1 | 2 | 68 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 4.35e-02 | 1.00e+00 | 4.496 | 1 | 4 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 4.35e-02 | 1.00e+00 | 4.496 | 1 | 4 | 71 |
GO:0034162 | toll-like receptor 9 signaling pathway | 4.41e-02 | 1.00e+00 | 4.476 | 1 | 4 | 72 |
GO:0009791 | post-embryonic development | 4.47e-02 | 1.00e+00 | 4.456 | 1 | 3 | 73 |
GO:0034134 | toll-like receptor 2 signaling pathway | 4.47e-02 | 1.00e+00 | 4.456 | 1 | 4 | 73 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 2 | 74 |
GO:0002020 | protease binding | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 6 | 74 |
GO:0060070 | canonical Wnt signaling pathway | 4.59e-02 | 1.00e+00 | 4.417 | 1 | 4 | 75 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 3 | 76 |
GO:0010629 | negative regulation of gene expression | 4.70e-02 | 1.00e+00 | 4.379 | 1 | 4 | 77 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 3 | 78 |
GO:0034138 | toll-like receptor 3 signaling pathway | 4.82e-02 | 1.00e+00 | 4.342 | 1 | 3 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 5 | 80 |
GO:0045177 | apical part of cell | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 3 | 81 |
GO:0071222 | cellular response to lipopolysaccharide | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 4 | 81 |
GO:0009653 | anatomical structure morphogenesis | 5.06e-02 | 1.00e+00 | 4.271 | 1 | 2 | 83 |
GO:0045087 | innate immune response | 5.06e-02 | 1.00e+00 | 2.427 | 2 | 15 | 596 |
GO:0009952 | anterior/posterior pattern specification | 5.06e-02 | 1.00e+00 | 4.271 | 1 | 4 | 83 |
GO:0050852 | T cell receptor signaling pathway | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 2 | 85 |
GO:0003690 | double-stranded DNA binding | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 3 | 86 |
GO:0006979 | response to oxidative stress | 5.30e-02 | 1.00e+00 | 4.203 | 1 | 6 | 87 |
GO:0005829 | cytosol | 5.42e-02 | 1.00e+00 | 1.361 | 4 | 86 | 2496 |
GO:0016363 | nuclear matrix | 5.54e-02 | 1.00e+00 | 4.138 | 1 | 6 | 91 |
GO:0034142 | toll-like receptor 4 signaling pathway | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 4 | 96 |
GO:0016568 | chromatin modification | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 4 | 98 |
GO:0005506 | iron ion binding | 6.37e-02 | 1.00e+00 | 3.932 | 1 | 3 | 105 |
GO:0030496 | midbody | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 2 | 108 |
GO:0002224 | toll-like receptor signaling pathway | 6.60e-02 | 1.00e+00 | 3.878 | 1 | 4 | 109 |
GO:0005815 | microtubule organizing center | 6.60e-02 | 1.00e+00 | 3.878 | 1 | 3 | 109 |
GO:0051056 | regulation of small GTPase mediated signal transduction | 6.95e-02 | 1.00e+00 | 3.801 | 1 | 3 | 115 |
GO:0030036 | actin cytoskeleton organization | 7.42e-02 | 1.00e+00 | 3.704 | 1 | 3 | 123 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 7.48e-02 | 1.00e+00 | 3.692 | 1 | 5 | 124 |
GO:0000790 | nuclear chromatin | 7.77e-02 | 1.00e+00 | 3.635 | 1 | 6 | 129 |
GO:0005911 | cell-cell junction | 8.18e-02 | 1.00e+00 | 3.559 | 1 | 2 | 136 |
GO:0061024 | membrane organization | 8.69e-02 | 1.00e+00 | 3.466 | 1 | 4 | 145 |
GO:0010628 | positive regulation of gene expression | 8.75e-02 | 1.00e+00 | 3.456 | 1 | 7 | 146 |
GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 8.81e-02 | 1.00e+00 | 3.446 | 1 | 6 | 147 |
GO:0006974 | cellular response to DNA damage stimulus | 9.04e-02 | 1.00e+00 | 3.408 | 1 | 7 | 151 |
GO:0043005 | neuron projection | 9.38e-02 | 1.00e+00 | 3.352 | 1 | 3 | 157 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 9.84e-02 | 1.00e+00 | 3.280 | 1 | 12 | 165 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 5 | 168 |
GO:0031625 | ubiquitin protein ligase binding | 1.06e-01 | 1.00e+00 | 3.170 | 1 | 5 | 178 |
GO:0003714 | transcription corepressor activity | 1.06e-01 | 1.00e+00 | 3.170 | 1 | 11 | 178 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.12e-01 | 1.00e+00 | 3.084 | 1 | 5 | 189 |
GO:0003924 | GTPase activity | 1.16e-01 | 1.00e+00 | 3.024 | 1 | 7 | 197 |
GO:0001701 | in utero embryonic development | 1.19e-01 | 1.00e+00 | 2.995 | 1 | 8 | 201 |
GO:0008270 | zinc ion binding | 1.24e-01 | 1.00e+00 | 1.685 | 2 | 27 | 997 |
GO:0006184 | GTP catabolic process | 1.26e-01 | 1.00e+00 | 2.905 | 1 | 7 | 214 |
GO:0003713 | transcription coactivator activity | 1.39e-01 | 1.00e+00 | 2.757 | 1 | 24 | 237 |
GO:0005654 | nucleoplasm | 1.42e-01 | 1.00e+00 | 1.567 | 2 | 64 | 1082 |
GO:0043025 | neuronal cell body | 1.43e-01 | 1.00e+00 | 2.710 | 1 | 9 | 245 |
GO:0007283 | spermatogenesis | 1.52e-01 | 1.00e+00 | 2.613 | 1 | 3 | 262 |
GO:0006281 | DNA repair | 1.52e-01 | 1.00e+00 | 2.618 | 1 | 14 | 261 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 1.56e-01 | 1.00e+00 | 2.575 | 1 | 7 | 269 |
GO:0007264 | small GTPase mediated signal transduction | 1.61e-01 | 1.00e+00 | 2.522 | 1 | 3 | 279 |
GO:0042493 | response to drug | 1.64e-01 | 1.00e+00 | 2.496 | 1 | 6 | 284 |
GO:0030154 | cell differentiation | 1.73e-01 | 1.00e+00 | 2.413 | 1 | 5 | 301 |
GO:0005525 | GTP binding | 1.78e-01 | 1.00e+00 | 2.370 | 1 | 12 | 310 |
GO:0019901 | protein kinase binding | 1.81e-01 | 1.00e+00 | 2.338 | 1 | 18 | 317 |
GO:0007411 | axon guidance | 1.82e-01 | 1.00e+00 | 2.329 | 1 | 5 | 319 |
GO:0005737 | cytoplasm | 1.87e-01 | 1.00e+00 | 0.767 | 4 | 124 | 3767 |
GO:0030054 | cell junction | 1.91e-01 | 1.00e+00 | 2.254 | 1 | 5 | 336 |
GO:0000139 | Golgi membrane | 2.04e-01 | 1.00e+00 | 2.150 | 1 | 7 | 361 |
GO:0006351 | transcription, DNA-templated | 2.26e-01 | 1.00e+00 | 1.148 | 2 | 57 | 1446 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.30e-01 | 1.00e+00 | 1.956 | 1 | 24 | 413 |
GO:0055114 | oxidation-reduction process | 2.34e-01 | 1.00e+00 | 1.932 | 1 | 10 | 420 |
GO:0043066 | negative regulation of apoptotic process | 2.36e-01 | 1.00e+00 | 1.918 | 1 | 16 | 424 |
GO:0055085 | transmembrane transport | 2.41e-01 | 1.00e+00 | 1.881 | 1 | 8 | 435 |
GO:0007596 | blood coagulation | 2.51e-01 | 1.00e+00 | 1.816 | 1 | 11 | 455 |
GO:0005730 | nucleolus | 2.73e-01 | 1.00e+00 | 0.966 | 2 | 66 | 1641 |
GO:0016020 | membrane | 2.83e-01 | 1.00e+00 | 0.931 | 2 | 46 | 1681 |
GO:0006915 | apoptotic process | 2.98e-01 | 1.00e+00 | 1.530 | 1 | 12 | 555 |
GO:0042803 | protein homodimerization activity | 3.16e-01 | 1.00e+00 | 1.429 | 1 | 19 | 595 |
GO:0070062 | extracellular vesicular exosome | 4.56e-01 | 1.00e+00 | 0.417 | 2 | 57 | 2400 |
GO:0005739 | mitochondrion | 4.76e-01 | 1.00e+00 | 0.683 | 1 | 23 | 998 |
GO:0044822 | poly(A) RNA binding | 4.96e-01 | 1.00e+00 | 0.602 | 1 | 50 | 1056 |
GO:0005886 | plasma membrane | 8.31e-01 | 1.00e+00 | -0.688 | 1 | 49 | 2582 |