int-snw-6334

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.813	2.82e-15	6.25e-04	4.06e-03

chia-screen-data-Fav-int-snw-6334 subnetwork

Genes (16)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
EIF2S2	8894	9	-2.999	2.968	81	Yes	Yes
PHB2	11331	5	-2.236	2.994	140	Yes	-
[ SCN8A ]	6334	1	-1.173	2.813	5	-	-
PHB	5245	15	-2.743	3.004	127	Yes	Yes
ICT1	3396	2	-2.210	2.813	208	Yes	-
TADA2B	93624	11	-3.061	3.082	19	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
EIF2B2	8892	8	-2.462	2.968	95	Yes	Yes
APC	324	13	-2.293	3.004	353	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
GSTP1	2950	3	-2.251	2.955	59	Yes	-
MAPK14	1432	4	-1.902	2.955	272	-	-
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes
FUBP1	8880	3	-2.414	2.955	23	Yes	Yes

Interactions (18)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EIF2B2	8892	TADA2B	93624	pp	--	int.I2D: BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly, MINT_Fly
ICT1	3396	PHB2	11331	pp	--	int.I2D: BioGrid
MAPK14	1432	DDIT3	1649	pp	--	int.I2D: BCI, BioGrid, HPRD; int.HPRD: in vitro
PHB	5245	SCN8A	6334	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
MAPK14	1432	FUBP1	8880	pp	--	int.I2D: BioGrid
PHB	5245	PHB2	11331	pp	--	int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast
MAPK14	1432	EIF2B2	8892	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
PSMD2	5708	EIF2B2	8892	pp	--	int.I2D: IntAct_Yeast
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
APC	324	PHB	5245	pp	--	int.I2D: Jorgensen_EphR
DDIT3	1649	GSTP1	2950	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
ICT1	3396	PHB	5245	pp	--	int.I2D: BioGrid
EIF2B2	8892	EIF2S2	8894	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh
MAPK14	1432	GSTP1	2950	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BCI
MAPK14	1432	SCN8A	6334	pp	--	int.I2D: HPRD; int.HPRD: in vivo
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
PSMD2	5708	PHB2	11331	pp	--	int.I2D: IntAct_Yeast

Related GO terms (352)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0044212	transcription regulatory region DNA binding	2.90e-05	4.18e-01	4.424	4	17	168
GO:0010467	gene expression	5.23e-05	7.54e-01	3.015	6	45	669
GO:0005654	nucleoplasm	8.21e-05	1.00e+00	2.544	7	64	1082
GO:0042789	mRNA transcription from RNA polymerase II promoter	8.94e-05	1.00e+00	7.116	2	2	13
GO:0043409	negative regulation of MAPK cascade	8.94e-05	1.00e+00	7.116	2	2	13
GO:0090090	negative regulation of canonical Wnt signaling pathway	1.08e-04	1.00e+00	4.975	3	8	86
GO:0005829	cytosol	4.86e-04	1.00e+00	1.701	9	86	2496
GO:0006974	cellular response to DNA damage stimulus	5.70e-04	1.00e+00	4.163	3	7	151
GO:0042552	myelination	6.72e-04	1.00e+00	5.687	2	4	35
GO:0035019	somatic stem cell maintenance	8.78e-04	1.00e+00	5.494	2	6	40
GO:0070664	negative regulation of leukocyte proliferation	1.11e-03	1.00e+00	9.816	1	1	1
GO:0070126	mitochondrial translational termination	1.11e-03	1.00e+00	9.816	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	1.11e-03	1.00e+00	9.816	1	1	1
GO:0035732	nitric oxide storage	1.11e-03	1.00e+00	9.816	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	1.11e-03	1.00e+00	9.816	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	1.11e-03	1.00e+00	9.816	1	1	1
GO:0097057	TRAF2-GSTP1 complex	1.11e-03	1.00e+00	9.816	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	1.11e-03	1.00e+00	9.816	1	1	1
GO:0042483	negative regulation of odontogenesis	1.11e-03	1.00e+00	9.816	1	1	1
GO:0070026	nitric oxide binding	1.11e-03	1.00e+00	9.816	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1.11e-03	1.00e+00	9.816	1	1	1
GO:0035731	dinitrosyl-iron complex binding	1.11e-03	1.00e+00	9.816	1	1	1
GO:0016150	translation release factor activity, codon nonspecific	1.11e-03	1.00e+00	9.816	1	1	1
GO:0038066	p38MAPK cascade	1.11e-03	1.00e+00	9.816	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	1.11e-03	1.00e+00	9.816	1	1	1
GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	1.11e-03	1.00e+00	9.816	1	1	1
GO:0035730	S-nitrosoglutathione binding	1.11e-03	1.00e+00	9.816	1	1	1
GO:0003743	translation initiation factor activity	1.32e-03	1.00e+00	5.201	2	7	49
GO:0005515	protein binding	1.51e-03	1.00e+00	0.960	13	198	6024
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	2.22e-03	1.00e+00	8.816	1	1	2
GO:0060242	contact inhibition	2.22e-03	1.00e+00	8.816	1	1	2
GO:0009890	negative regulation of biosynthetic process	2.22e-03	1.00e+00	8.816	1	1	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	2.22e-03	1.00e+00	8.816	1	1	2
GO:0002176	male germ cell proliferation	2.22e-03	1.00e+00	8.816	1	1	2
GO:0009786	regulation of asymmetric cell division	2.22e-03	1.00e+00	8.816	1	1	2
GO:0019207	kinase regulator activity	2.22e-03	1.00e+00	8.816	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2.22e-03	1.00e+00	8.816	1	1	2
GO:0009798	axis specification	2.22e-03	1.00e+00	8.816	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	2.22e-03	1.00e+00	8.816	1	1	2
GO:0035726	common myeloid progenitor cell proliferation	3.32e-03	1.00e+00	8.231	1	1	3
GO:0060913	cardiac cell fate determination	3.32e-03	1.00e+00	8.231	1	1	3
GO:0005850	eukaryotic translation initiation factor 2 complex	3.32e-03	1.00e+00	8.231	1	1	3
GO:0090400	stress-induced premature senescence	3.32e-03	1.00e+00	8.231	1	1	3
GO:0004045	aminoacyl-tRNA hydrolase activity	3.32e-03	1.00e+00	8.231	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	3.32e-03	1.00e+00	8.231	1	1	3
GO:0071222	cellular response to lipopolysaccharide	3.55e-03	1.00e+00	4.476	2	4	81
GO:0006355	regulation of transcription, DNA-templated	3.59e-03	1.00e+00	2.177	5	43	997
GO:0005739	mitochondrion	3.60e-03	1.00e+00	2.175	5	23	998
GO:0051716	cellular response to stimulus	4.43e-03	1.00e+00	7.816	1	4	4
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	4.43e-03	1.00e+00	7.816	1	1	4
GO:0046523	S-methyl-5-thioribose-1-phosphate isomerase activity	4.43e-03	1.00e+00	7.816	1	3	4
GO:0019887	protein kinase regulator activity	4.43e-03	1.00e+00	7.816	1	1	4
GO:0001649	osteoblast differentiation	4.56e-03	1.00e+00	4.293	2	5	92
GO:0007417	central nervous system development	4.95e-03	1.00e+00	4.231	2	5	96
GO:0070461	SAGA-type complex	5.54e-03	1.00e+00	7.494	1	2	5
GO:0001714	endodermal cell fate specification	5.54e-03	1.00e+00	7.494	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	5.54e-03	1.00e+00	7.494	1	2	5
GO:0043620	regulation of DNA-templated transcription in response to stress	5.54e-03	1.00e+00	7.494	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	5.54e-03	1.00e+00	7.494	1	2	5
GO:0051525	NFAT protein binding	5.54e-03	1.00e+00	7.494	1	2	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	5.54e-03	1.00e+00	7.494	1	1	5
GO:1901741	positive regulation of myoblast fusion	5.54e-03	1.00e+00	7.494	1	1	5
GO:0030858	positive regulation of epithelial cell differentiation	6.64e-03	1.00e+00	7.231	1	1	6
GO:0050847	progesterone receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	2	6
GO:0060744	mammary gland branching involved in thelarche	6.64e-03	1.00e+00	7.231	1	2	6
GO:0032873	negative regulation of stress-activated MAPK cascade	6.64e-03	1.00e+00	7.231	1	2	6
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	6.64e-03	1.00e+00	7.231	1	3	6
GO:0032691	negative regulation of interleukin-1 beta production	6.64e-03	1.00e+00	7.231	1	1	6
GO:0005851	eukaryotic translation initiation factor 2B complex	6.64e-03	1.00e+00	7.231	1	4	6
GO:0008432	JUN kinase binding	6.64e-03	1.00e+00	7.231	1	1	6
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	6.64e-03	1.00e+00	7.231	1	2	6
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	7.74e-03	1.00e+00	7.009	1	2	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	7.74e-03	1.00e+00	7.009	1	1	7
GO:0071354	cellular response to interleukin-6	7.74e-03	1.00e+00	7.009	1	2	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	7.74e-03	1.00e+00	7.009	1	2	7
GO:0032930	positive regulation of superoxide anion generation	7.74e-03	1.00e+00	7.009	1	2	7
GO:0002674	negative regulation of acute inflammatory response	7.74e-03	1.00e+00	7.009	1	1	7
GO:0007050	cell cycle arrest	8.13e-03	1.00e+00	3.862	2	5	124
GO:0032872	regulation of stress-activated MAPK cascade	8.84e-03	1.00e+00	6.816	1	1	8
GO:0045670	regulation of osteoclast differentiation	8.84e-03	1.00e+00	6.816	1	2	8
GO:0001955	blood vessel maturation	8.84e-03	1.00e+00	6.816	1	1	8
GO:0010831	positive regulation of myotube differentiation	8.84e-03	1.00e+00	6.816	1	1	8
GO:0006413	translational initiation	9.04e-03	1.00e+00	3.783	2	7	131
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	9.54e-03	1.00e+00	2.192	4	41	789
GO:0045892	negative regulation of transcription, DNA-templated	9.89e-03	1.00e+00	2.711	3	24	413
GO:0045667	regulation of osteoblast differentiation	9.94e-03	1.00e+00	6.646	1	1	9
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	9.94e-03	1.00e+00	6.646	1	1	9
GO:0000302	response to reactive oxygen species	9.94e-03	1.00e+00	6.646	1	1	9
GO:0019509	L-methionine biosynthetic process from methylthioadenosine	9.94e-03	1.00e+00	6.646	1	3	9
GO:0006983	ER overload response	9.94e-03	1.00e+00	6.646	1	1	9
GO:0010944	negative regulation of transcription by competitive promoter binding	9.94e-03	1.00e+00	6.646	1	1	9
GO:0032495	response to muramyl dipeptide	9.94e-03	1.00e+00	6.646	1	2	9
GO:0005634	nucleus	1.06e-02	1.00e+00	0.984	10	159	4559
GO:0043194	axon initial segment	1.10e-02	1.00e+00	6.494	1	1	10
GO:0031274	positive regulation of pseudopodium assembly	1.10e-02	1.00e+00	6.494	1	2	10
GO:0001518	voltage-gated sodium channel complex	1.10e-02	1.00e+00	6.494	1	1	10
GO:0035413	positive regulation of catenin import into nucleus	1.10e-02	1.00e+00	6.494	1	2	10
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	1.10e-02	1.00e+00	6.494	1	2	10
GO:0030877	beta-catenin destruction complex	1.10e-02	1.00e+00	6.494	1	2	10
GO:0042981	regulation of apoptotic process	1.17e-02	1.00e+00	3.587	2	4	150
GO:0045663	positive regulation of myoblast differentiation	1.21e-02	1.00e+00	6.357	1	2	11
GO:0051010	microtubule plus-end binding	1.21e-02	1.00e+00	6.357	1	1	11
GO:0045662	negative regulation of myoblast differentiation	1.21e-02	1.00e+00	6.357	1	3	11
GO:0019395	fatty acid oxidation	1.21e-02	1.00e+00	6.357	1	2	11
GO:0004707	MAP kinase activity	1.21e-02	1.00e+00	6.357	1	1	11
GO:0031116	positive regulation of microtubule polymerization	1.21e-02	1.00e+00	6.357	1	1	11
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	1.21e-02	1.00e+00	6.357	1	1	11
GO:0042770	signal transduction in response to DNA damage	1.21e-02	1.00e+00	6.357	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.21e-02	1.00e+00	6.357	1	4	11
GO:0032886	regulation of microtubule-based process	1.32e-02	1.00e+00	6.231	1	1	12
GO:0070935	3'-UTR-mediated mRNA stabilization	1.32e-02	1.00e+00	6.231	1	3	12
GO:0051146	striated muscle cell differentiation	1.32e-02	1.00e+00	6.231	1	1	12
GO:0045295	gamma-catenin binding	1.32e-02	1.00e+00	6.231	1	1	12
GO:0050905	neuromuscular process	1.32e-02	1.00e+00	6.231	1	1	12
GO:0005838	proteasome regulatory particle	1.32e-02	1.00e+00	6.231	1	1	12
GO:0035198	miRNA binding	1.32e-02	1.00e+00	6.231	1	1	12
GO:0043508	negative regulation of JUN kinase activity	1.43e-02	1.00e+00	6.116	1	1	13
GO:0071480	cellular response to gamma radiation	1.43e-02	1.00e+00	6.116	1	1	13
GO:0004708	MAP kinase kinase activity	1.43e-02	1.00e+00	6.116	1	1	13
GO:0060766	negative regulation of androgen receptor signaling pathway	1.43e-02	1.00e+00	6.116	1	3	13
GO:0044295	axonal growth cone	1.43e-02	1.00e+00	6.116	1	1	13
GO:0030914	STAGA complex	1.43e-02	1.00e+00	6.116	1	3	13
GO:0030234	enzyme regulator activity	1.43e-02	1.00e+00	6.116	1	2	13
GO:0044267	cellular protein metabolic process	1.44e-02	1.00e+00	2.512	3	20	474
GO:0035371	microtubule plus-end	1.54e-02	1.00e+00	6.009	1	1	14
GO:0005762	mitochondrial large ribosomal subunit	1.54e-02	1.00e+00	6.009	1	1	14
GO:0003714	transcription corepressor activity	1.62e-02	1.00e+00	3.340	2	11	178
GO:0042307	positive regulation of protein import into nucleus	1.65e-02	1.00e+00	5.909	1	4	15
GO:0001824	blastocyst development	1.65e-02	1.00e+00	5.909	1	2	15
GO:0060749	mammary gland alveolus development	1.65e-02	1.00e+00	5.909	1	2	15
GO:0007026	negative regulation of microtubule depolymerization	1.76e-02	1.00e+00	5.816	1	1	16
GO:0033268	node of Ranvier	1.76e-02	1.00e+00	5.816	1	2	16
GO:0042176	regulation of protein catabolic process	1.76e-02	1.00e+00	5.816	1	2	16
GO:0046716	muscle cell cellular homeostasis	1.76e-02	1.00e+00	5.816	1	1	16
GO:0051276	chromosome organization	1.76e-02	1.00e+00	5.816	1	2	16
GO:0005248	voltage-gated sodium channel activity	1.76e-02	1.00e+00	5.816	1	1	16
GO:0070372	regulation of ERK1 and ERK2 cascade	1.87e-02	1.00e+00	5.729	1	2	17
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.87e-02	1.00e+00	5.729	1	3	17
GO:0022624	proteasome accessory complex	1.87e-02	1.00e+00	5.729	1	1	17
GO:0019228	neuronal action potential	1.98e-02	1.00e+00	5.646	1	1	18
GO:0031122	cytoplasmic microtubule organization	1.98e-02	1.00e+00	5.646	1	1	18
GO:0004364	glutathione transferase activity	1.98e-02	1.00e+00	5.646	1	1	18
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	2.09e-02	1.00e+00	5.568	1	2	19
GO:0006915	apoptotic process	2.18e-02	1.00e+00	2.285	3	12	555
GO:0048010	vascular endothelial growth factor receptor signaling pathway	2.20e-02	1.00e+00	5.494	1	1	20
GO:0001502	cartilage condensation	2.20e-02	1.00e+00	5.494	1	1	20
GO:0032757	positive regulation of interleukin-8 production	2.20e-02	1.00e+00	5.494	1	1	20
GO:0035924	cellular response to vascular endothelial growth factor stimulus	2.20e-02	1.00e+00	5.494	1	1	20
GO:1901687	glutathione derivative biosynthetic process	2.20e-02	1.00e+00	5.494	1	1	20
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	2.20e-02	1.00e+00	5.494	1	3	20
GO:0014003	oligodendrocyte development	2.20e-02	1.00e+00	5.494	1	5	20
GO:0045648	positive regulation of erythrocyte differentiation	2.31e-02	1.00e+00	5.424	1	1	21
GO:0009954	proximal/distal pattern formation	2.31e-02	1.00e+00	5.424	1	1	21
GO:0016575	histone deacetylation	2.31e-02	1.00e+00	5.424	1	3	21
GO:0000281	mitotic cytokinesis	2.31e-02	1.00e+00	5.424	1	2	21
GO:0030316	osteoclast differentiation	2.41e-02	1.00e+00	5.357	1	2	22
GO:0048147	negative regulation of fibroblast proliferation	2.41e-02	1.00e+00	5.357	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.41e-02	1.00e+00	5.357	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	2.41e-02	1.00e+00	5.357	1	4	22
GO:0016071	mRNA metabolic process	2.48e-02	1.00e+00	3.015	2	8	223
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.52e-02	1.00e+00	5.293	1	1	23
GO:0071479	cellular response to ionizing radiation	2.52e-02	1.00e+00	5.293	1	1	23
GO:2000379	positive regulation of reactive oxygen species metabolic process	2.52e-02	1.00e+00	5.293	1	2	23
GO:0044822	poly(A) RNA binding	2.56e-02	1.00e+00	1.772	4	50	1056
GO:0006412	translation	2.62e-02	1.00e+00	2.971	2	8	230
GO:0008135	translation factor activity, nucleic acid binding	2.63e-02	1.00e+00	5.231	1	3	24
GO:0045296	cadherin binding	2.63e-02	1.00e+00	5.231	1	3	24
GO:0007422	peripheral nervous system development	2.74e-02	1.00e+00	5.172	1	2	25
GO:0086010	membrane depolarization during action potential	2.74e-02	1.00e+00	5.172	1	2	25
GO:0035329	hippo signaling	2.85e-02	1.00e+00	5.116	1	5	26
GO:0051209	release of sequestered calcium ion into cytosol	2.85e-02	1.00e+00	5.116	1	1	26
GO:0008134	transcription factor binding	2.88e-02	1.00e+00	2.897	2	18	242
GO:0051149	positive regulation of muscle cell differentiation	2.96e-02	1.00e+00	5.061	1	4	27
GO:0032720	negative regulation of tumor necrosis factor production	2.96e-02	1.00e+00	5.061	1	2	27
GO:0000077	DNA damage checkpoint	2.96e-02	1.00e+00	5.061	1	1	27
GO:0030331	estrogen receptor binding	2.96e-02	1.00e+00	5.061	1	2	27
GO:0006749	glutathione metabolic process	2.96e-02	1.00e+00	5.061	1	1	27
GO:0016070	RNA metabolic process	2.99e-02	1.00e+00	2.868	2	8	247
GO:0007628	adult walking behavior	3.06e-02	1.00e+00	5.009	1	3	28
GO:0071897	DNA biosynthetic process	3.06e-02	1.00e+00	5.009	1	1	28
GO:0070830	tight junction assembly	3.06e-02	1.00e+00	5.009	1	1	28
GO:0005913	cell-cell adherens junction	3.17e-02	1.00e+00	4.958	1	3	29
GO:0031663	lipopolysaccharide-mediated signaling pathway	3.17e-02	1.00e+00	4.958	1	2	29
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	3.28e-02	1.00e+00	4.909	1	2	30
GO:0009953	dorsal/ventral pattern formation	3.39e-02	1.00e+00	4.862	1	2	31
GO:0042594	response to starvation	3.39e-02	1.00e+00	4.862	1	4	31
GO:0070373	negative regulation of ERK1 and ERK2 cascade	3.39e-02	1.00e+00	4.862	1	1	31
GO:0007094	mitotic spindle assembly checkpoint	3.39e-02	1.00e+00	4.862	1	3	31
GO:0043407	negative regulation of MAP kinase activity	3.49e-02	1.00e+00	4.816	1	1	32
GO:0002062	chondrocyte differentiation	3.49e-02	1.00e+00	4.816	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.49e-02	1.00e+00	4.816	1	2	32
GO:0033077	T cell differentiation in thymus	3.60e-02	1.00e+00	4.772	1	1	33
GO:0005743	mitochondrial inner membrane	3.69e-02	1.00e+00	2.702	2	6	277
GO:0042692	muscle cell differentiation	3.71e-02	1.00e+00	4.729	1	4	34
GO:0001942	hair follicle development	3.81e-02	1.00e+00	4.687	1	2	35
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	3.81e-02	1.00e+00	4.687	1	2	35
GO:0048538	thymus development	3.92e-02	1.00e+00	4.646	1	2	36
GO:0006446	regulation of translational initiation	3.92e-02	1.00e+00	4.646	1	4	36
GO:0003700	sequence-specific DNA binding transcription factor activity	3.96e-02	1.00e+00	1.952	3	39	699
GO:0001541	ovarian follicle development	4.03e-02	1.00e+00	4.607	1	2	37
GO:0003677	DNA binding	4.05e-02	1.00e+00	1.566	4	49	1218
GO:0051781	positive regulation of cell division	4.24e-02	1.00e+00	4.531	1	1	39
GO:0005881	cytoplasmic microtubule	4.35e-02	1.00e+00	4.494	1	1	40
GO:0045785	positive regulation of cell adhesion	4.35e-02	1.00e+00	4.494	1	2	40
GO:0009408	response to heat	4.35e-02	1.00e+00	4.494	1	6	40
GO:0007519	skeletal muscle tissue development	4.35e-02	1.00e+00	4.494	1	2	40
GO:0043434	response to peptide hormone	4.88e-02	1.00e+00	4.324	1	5	45
GO:0005524	ATP binding	4.95e-02	1.00e+00	1.474	4	31	1298
GO:0016328	lateral plasma membrane	4.99e-02	1.00e+00	4.293	1	3	46
GO:0043525	positive regulation of neuron apoptotic process	4.99e-02	1.00e+00	4.293	1	4	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	5.09e-02	1.00e+00	4.261	1	2	47
GO:0006814	sodium ion transport	5.30e-02	1.00e+00	4.201	1	1	49
GO:0000902	cell morphogenesis	5.30e-02	1.00e+00	4.201	1	4	49
GO:0006521	regulation of cellular amino acid metabolic process	5.41e-02	1.00e+00	4.172	1	1	50
GO:0006986	response to unfolded protein	5.41e-02	1.00e+00	4.172	1	4	50
GO:0003723	RNA binding	5.41e-02	1.00e+00	2.398	2	18	342
GO:0045732	positive regulation of protein catabolic process	5.41e-02	1.00e+00	4.172	1	1	50
GO:0060041	retina development in camera-type eye	5.51e-02	1.00e+00	4.144	1	2	51
GO:0034976	response to endoplasmic reticulum stress	5.51e-02	1.00e+00	4.144	1	2	51
GO:0045454	cell redox homeostasis	5.51e-02	1.00e+00	4.144	1	1	51
GO:0043565	sequence-specific DNA binding	5.52e-02	1.00e+00	2.381	2	11	346
GO:0009611	response to wounding	5.62e-02	1.00e+00	4.116	1	5	52
GO:0035725	sodium ion transmembrane transport	5.62e-02	1.00e+00	4.116	1	1	52
GO:0008285	negative regulation of cell proliferation	5.72e-02	1.00e+00	2.353	2	10	353
GO:0051403	stress-activated MAPK cascade	5.83e-02	1.00e+00	4.061	1	2	54
GO:0000502	proteasome complex	6.25e-02	1.00e+00	3.958	1	3	58
GO:0006396	RNA processing	6.35e-02	1.00e+00	3.933	1	5	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	6.35e-02	1.00e+00	3.933	1	6	59
GO:0008013	beta-catenin binding	6.46e-02	1.00e+00	3.909	1	9	60
GO:0006987	activation of signaling protein activity involved in unfolded protein response	6.56e-02	1.00e+00	3.885	1	2	61
GO:0000776	kinetochore	6.77e-02	1.00e+00	3.839	1	5	63
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.87e-02	1.00e+00	3.816	1	1	64
GO:0009749	response to glucose	6.87e-02	1.00e+00	3.816	1	7	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.98e-02	1.00e+00	3.794	1	2	65
GO:0009636	response to toxic substance	6.98e-02	1.00e+00	3.794	1	1	65
GO:0034166	toll-like receptor 10 signaling pathway	6.98e-02	1.00e+00	3.794	1	4	65
GO:0007409	axonogenesis	6.98e-02	1.00e+00	3.794	1	2	65
GO:0006469	negative regulation of protein kinase activity	6.98e-02	1.00e+00	3.794	1	4	65
GO:0034146	toll-like receptor 5 signaling pathway	6.98e-02	1.00e+00	3.794	1	4	65
GO:0003697	single-stranded DNA binding	7.29e-02	1.00e+00	3.729	1	5	68
GO:0010468	regulation of gene expression	7.29e-02	1.00e+00	3.729	1	2	68
GO:0018105	peptidyl-serine phosphorylation	7.39e-02	1.00e+00	3.708	1	2	69
GO:0032587	ruffle membrane	7.49e-02	1.00e+00	3.687	1	3	70
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.49e-02	1.00e+00	3.687	1	2	70
GO:0005085	guanyl-nucleotide exchange factor activity	7.60e-02	1.00e+00	3.666	1	5	71
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	7.60e-02	1.00e+00	3.666	1	4	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	7.60e-02	1.00e+00	3.666	1	4	71
GO:0034162	toll-like receptor 9 signaling pathway	7.70e-02	1.00e+00	3.646	1	4	72
GO:0042826	histone deacetylase binding	7.70e-02	1.00e+00	3.646	1	4	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	7.70e-02	1.00e+00	3.646	1	1	72
GO:0006366	transcription from RNA polymerase II promoter	7.73e-02	1.00e+00	2.105	2	30	419
GO:0034134	toll-like receptor 2 signaling pathway	7.80e-02	1.00e+00	3.626	1	4	73
GO:0043066	negative regulation of apoptotic process	7.89e-02	1.00e+00	2.088	2	16	424
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	7.90e-02	1.00e+00	3.607	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.90e-02	1.00e+00	3.607	1	2	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	8.01e-02	1.00e+00	3.587	1	1	75
GO:0060070	canonical Wnt signaling pathway	8.01e-02	1.00e+00	3.587	1	4	75
GO:0008584	male gonad development	8.01e-02	1.00e+00	3.587	1	3	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	8.01e-02	1.00e+00	3.587	1	1	75
GO:0007265	Ras protein signal transduction	8.01e-02	1.00e+00	3.587	1	3	75
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	8.11e-02	1.00e+00	3.568	1	3	76
GO:0001822	kidney development	8.31e-02	1.00e+00	3.531	1	3	78
GO:0071013	catalytic step 2 spliceosome	8.31e-02	1.00e+00	3.531	1	7	78
GO:0002756	MyD88-independent toll-like receptor signaling pathway	8.31e-02	1.00e+00	3.531	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	8.42e-02	1.00e+00	3.512	1	3	79
GO:0030968	endoplasmic reticulum unfolded protein response	8.42e-02	1.00e+00	3.512	1	2	79
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.42e-02	1.00e+00	3.512	1	2	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	8.52e-02	1.00e+00	3.494	1	5	80
GO:0009653	anatomical structure morphogenesis	8.82e-02	1.00e+00	3.441	1	2	83
GO:0007517	muscle organ development	8.82e-02	1.00e+00	3.441	1	4	83
GO:0009952	anterior/posterior pattern specification	8.82e-02	1.00e+00	3.441	1	4	83
GO:0005923	tight junction	9.13e-02	1.00e+00	3.390	1	2	86
GO:0000922	spindle pole	9.23e-02	1.00e+00	3.373	1	4	87
GO:0000187	activation of MAPK activity	9.53e-02	1.00e+00	3.324	1	3	90
GO:0016363	nuclear matrix	9.64e-02	1.00e+00	3.308	1	6	91
GO:0006928	cellular component movement	9.64e-02	1.00e+00	3.308	1	3	91
GO:0045893	positive regulation of transcription, DNA-templated	9.69e-02	1.00e+00	1.915	2	24	478
GO:0005737	cytoplasm	9.70e-02	1.00e+00	0.744	7	124	3767
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	9.74e-02	1.00e+00	3.293	1	1	92
GO:0005770	late endosome	9.84e-02	1.00e+00	3.277	1	2	93
GO:0034142	toll-like receptor 4 signaling pathway	1.01e-01	1.00e+00	3.231	1	4	96
GO:0030018	Z disc	1.02e-01	1.00e+00	3.216	1	4	97
GO:0034765	regulation of ion transmembrane transport	1.03e-01	1.00e+00	3.201	1	2	98
GO:0006805	xenobiotic metabolic process	1.08e-01	1.00e+00	3.130	1	2	103
GO:0007605	sensory perception of sound	1.09e-01	1.00e+00	3.116	1	2	104
GO:0006935	chemotaxis	1.10e-01	1.00e+00	3.102	1	3	105
GO:0016023	cytoplasmic membrane-bounded vesicle	1.10e-01	1.00e+00	3.102	1	8	105
GO:0070062	extracellular vesicular exosome	1.13e-01	1.00e+00	0.909	5	57	2400
GO:0002224	toll-like receptor signaling pathway	1.14e-01	1.00e+00	3.048	1	4	109
GO:0030308	negative regulation of cell growth	1.15e-01	1.00e+00	3.035	1	6	110
GO:0006461	protein complex assembly	1.16e-01	1.00e+00	3.022	1	4	111
GO:0030529	ribonucleoprotein complex	1.17e-01	1.00e+00	3.009	1	5	112
GO:0000209	protein polyubiquitination	1.21e-01	1.00e+00	2.958	1	3	116
GO:0006006	glucose metabolic process	1.23e-01	1.00e+00	2.933	1	5	118
GO:0006325	chromatin organization	1.23e-01	1.00e+00	2.933	1	12	118
GO:0030027	lamellipodium	1.30e-01	1.00e+00	2.850	1	7	125
GO:0030335	positive regulation of cell migration	1.32e-01	1.00e+00	2.827	1	5	127
GO:0016477	cell migration	1.33e-01	1.00e+00	2.816	1	4	128
GO:0031982	vesicle	1.36e-01	1.00e+00	2.783	1	3	131
GO:0016055	Wnt signaling pathway	1.43e-01	1.00e+00	2.708	1	4	138
GO:0010628	positive regulation of gene expression	1.50e-01	1.00e+00	2.626	1	7	146
GO:0008017	microtubule binding	1.51e-01	1.00e+00	2.616	1	2	147
GO:0007166	cell surface receptor signaling pathway	1.51e-01	1.00e+00	2.616	1	4	147
GO:0000082	G1/S transition of mitotic cell cycle	1.53e-01	1.00e+00	2.597	1	3	149
GO:0000398	mRNA splicing, via spliceosome	1.67e-01	1.00e+00	2.459	1	15	164
GO:0034641	cellular nitrogen compound metabolic process	1.74e-01	1.00e+00	2.398	1	2	171
GO:0005667	transcription factor complex	1.78e-01	1.00e+00	2.365	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.80e-01	1.00e+00	2.340	1	5	178
GO:0043547	positive regulation of GTPase activity	1.82e-01	1.00e+00	2.324	1	9	180
GO:0006367	transcription initiation from RNA polymerase II promoter	1.86e-01	1.00e+00	2.293	1	22	184
GO:0001525	angiogenesis	1.92e-01	1.00e+00	2.239	1	7	191
GO:0001701	in utero embryonic development	2.01e-01	1.00e+00	2.165	1	8	201
GO:0030168	platelet activation	2.05e-01	1.00e+00	2.137	1	6	205
GO:0005622	intracellular	2.07e-01	1.00e+00	2.123	1	6	207
GO:0006351	transcription, DNA-templated	2.12e-01	1.00e+00	0.903	3	57	1446
GO:0008380	RNA splicing	2.25e-01	1.00e+00	1.983	1	22	228
GO:0030425	dendrite	2.27e-01	1.00e+00	1.971	1	6	230
GO:0007399	nervous system development	2.28e-01	1.00e+00	1.964	1	6	231
GO:0003713	transcription coactivator activity	2.33e-01	1.00e+00	1.927	1	24	237
GO:0043025	neuronal cell body	2.40e-01	1.00e+00	1.879	1	9	245
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.56e-01	1.00e+00	1.772	1	23	264
GO:0043065	positive regulation of apoptotic process	2.59e-01	1.00e+00	1.750	1	7	268
GO:0048011	neurotrophin TRK receptor signaling pathway	2.60e-01	1.00e+00	1.745	1	7	269
GO:0007165	signal transduction	2.66e-01	1.00e+00	0.991	2	13	907
GO:0019899	enzyme binding	2.67e-01	1.00e+00	1.702	1	9	277
GO:0043234	protein complex	2.82e-01	1.00e+00	1.612	1	11	295
GO:0016020	membrane	2.84e-01	1.00e+00	0.686	3	46	1681
GO:0035556	intracellular signal transduction	2.88e-01	1.00e+00	1.573	1	9	303
GO:0004674	protein serine/threonine kinase activity	2.92e-01	1.00e+00	1.549	1	6	308
GO:0005525	GTP binding	2.94e-01	1.00e+00	1.540	1	12	310
GO:0019901	protein kinase binding	2.99e-01	1.00e+00	1.508	1	18	317
GO:0007411	axon guidance	3.01e-01	1.00e+00	1.499	1	5	319
GO:0005813	centrosome	3.06e-01	1.00e+00	1.467	1	7	326
GO:0003682	chromatin binding	3.07e-01	1.00e+00	1.463	1	19	327
GO:0008283	cell proliferation	3.08e-01	1.00e+00	1.459	1	14	328
GO:0007155	cell adhesion	3.40e-01	1.00e+00	1.289	1	5	369
GO:0046982	protein heterodimerization activity	3.48e-01	1.00e+00	1.246	1	8	380
GO:0000278	mitotic cell cycle	3.56e-01	1.00e+00	1.205	1	15	391
GO:0009986	cell surface	3.64e-01	1.00e+00	1.165	1	9	402
GO:0044281	small molecule metabolic process	3.94e-01	1.00e+00	0.574	2	20	1211
GO:0007596	blood coagulation	4.01e-01	1.00e+00	0.986	1	11	455
GO:0016032	viral process	4.53e-01	1.00e+00	0.755	1	26	534
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.76e-01	1.00e+00	0.661	1	37	570
GO:0045087	innate immune response	4.91e-01	1.00e+00	0.597	1	15	596
GO:0005886	plasma membrane	5.66e-01	1.00e+00	0.067	3	49	2582
GO:0005887	integral component of plasma membrane	6.38e-01	1.00e+00	0.022	1	10	888
GO:0005615	extracellular space	6.67e-01	1.00e+00	-0.086	1	20	957
GO:0008270	zinc ion binding	6.82e-01	1.00e+00	-0.145	1	27	997
GO:0046872	metal ion binding	7.81e-01	1.00e+00	-0.536	1	29	1307
GO:0005730	nucleolus	8.55e-01	1.00e+00	-0.864	1	66	1641
GO:0016021	integral component of membrane	9.06e-01	1.00e+00	-1.137	1	17	1982

chia-Fav

int-snw-6334

Statistics

Genes (16)

Interactions (18)

Related GO terms (352)