Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.869 | 7.06e-16 | 3.19e-04 | 2.52e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
HCFC1 | 3054 | 40 | -2.925 | 3.449 | 71 | Yes | Yes |
[ SALL1 ] | 6299 | 1 | -1.285 | 2.869 | 9 | - | - |
ZFP36 | 7538 | 10 | -2.968 | 2.869 | 24 | Yes | Yes |
PHB | 5245 | 15 | -2.743 | 3.004 | 127 | Yes | Yes |
HDAC1 | 3065 | 2 | -1.712 | 2.869 | 566 | - | - |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
BCL6B | 255877 | 2 | -2.723 | 2.869 | 3 | Yes | Yes |
SRSF3 | 6428 | 73 | -2.992 | 3.538 | 54 | Yes | - |
NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
CDX2 | 1045 | 3 | -2.037 | 2.955 | 33 | Yes | Yes |
SON | 6651 | 9 | -3.844 | 3.108 | 9 | Yes | Yes |
CDK12 | 51755 | 6 | -2.714 | 2.944 | 15 | Yes | - |
SUMO1 | 7341 | 7 | -1.696 | 3.050 | 439 | - | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
HDAC1 | 3065 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
SUMO1 | 7341 | CDK12 | 51755 | pp | -- | int.I2D: BioGrid |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
CDX2 | 1045 | SALL1 | 6299 | pp | -- | int.I2D: I2D-c_Mouse |
HCFC1 | 3054 | HDAC1 | 3065 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BCI, BioGrid, IntAct; int.Ravasi: - |
HCFC1 | 3054 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
HNRNPU | 3192 | SUMO1 | 7341 | pp | -- | int.I2D: BioGrid |
HDAC1 | 3065 | PHB | 5245 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.HPRD: in vivo |
SALL1 | 6299 | SUMO1 | 7341 | pp | -- | int.I2D: BioGrid, BIND |
SON | 6651 | SUMO1 | 7341 | pp | -- | int.I2D: BioGrid |
HDAC1 | 3065 | ZFP36 | 7538 | pp | -- | int.I2D: BioGrid |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
POU5F1 | 5460 | SUMO1 | 7341 | pp | -- | int.I2D: BioGrid, BioGrid_Mouse |
HDAC1 | 3065 | SALL1 | 6299 | pp | -- | int.I2D: HPRD; int.Ravasi: -; int.HPRD: in vivo |
CDX2 | 1045 | HDAC1 | 3065 | pp | -- | int.I2D: I2D-c_Mouse |
POU5F1 | 5460 | SALL1 | 6299 | pp | -- | int.I2D: IntAct_Mouse |
HDAC1 | 3065 | BCL6B | 255877 | pp | -- | int.I2D: BioGrid |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 7.08e-07 | 1.02e-02 | 3.562 | 7 | 37 | 570 |
GO:0005634 | nucleus | 1.04e-06 | 1.50e-02 | 1.562 | 14 | 159 | 4559 |
GO:0016575 | histone deacetylation | 1.20e-06 | 1.73e-02 | 7.102 | 3 | 3 | 21 |
GO:0005654 | nucleoplasm | 3.91e-06 | 5.63e-02 | 2.830 | 8 | 64 | 1082 |
GO:0044212 | transcription regulatory region DNA binding | 2.19e-05 | 3.16e-01 | 4.517 | 4 | 17 | 168 |
GO:0016607 | nuclear speck | 2.41e-05 | 3.47e-01 | 4.483 | 4 | 12 | 172 |
GO:0006366 | transcription from RNA polymerase II promoter | 4.77e-05 | 6.88e-01 | 3.520 | 5 | 30 | 419 |
GO:0008380 | RNA splicing | 7.24e-05 | 1.00e+00 | 4.076 | 4 | 22 | 228 |
GO:0060766 | negative regulation of androgen receptor signaling pathway | 7.82e-05 | 1.00e+00 | 7.209 | 2 | 3 | 13 |
GO:0003677 | DNA binding | 1.06e-04 | 1.00e+00 | 2.466 | 7 | 49 | 1218 |
GO:0016581 | NuRD complex | 1.20e-04 | 1.00e+00 | 6.909 | 2 | 2 | 16 |
GO:0004407 | histone deacetylase activity | 1.20e-04 | 1.00e+00 | 6.909 | 2 | 2 | 16 |
GO:0044822 | poly(A) RNA binding | 4.27e-04 | 1.00e+00 | 2.450 | 6 | 50 | 1056 |
GO:0010467 | gene expression | 4.31e-04 | 1.00e+00 | 2.845 | 5 | 45 | 669 |
GO:0005515 | protein binding | 4.61e-04 | 1.00e+00 | 1.053 | 13 | 198 | 6024 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 5.27e-04 | 1.00e+00 | 2.782 | 5 | 39 | 699 |
GO:0005730 | nucleolus | 6.85e-04 | 1.00e+00 | 2.036 | 7 | 66 | 1641 |
GO:0045892 | negative regulation of transcription, DNA-templated | 7.04e-04 | 1.00e+00 | 3.219 | 4 | 24 | 413 |
GO:0035019 | somatic stem cell maintenance | 7.70e-04 | 1.00e+00 | 5.587 | 2 | 6 | 40 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0031129 | inductive cell-cell signaling | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0072073 | kidney epithelium development | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:0042733 | embryonic digit morphogenesis | 1.06e-03 | 1.00e+00 | 5.355 | 2 | 2 | 47 |
GO:0045893 | positive regulation of transcription, DNA-templated | 1.22e-03 | 1.00e+00 | 3.008 | 4 | 24 | 478 |
GO:0008134 | transcription factor binding | 1.83e-03 | 1.00e+00 | 3.575 | 3 | 18 | 242 |
GO:0060242 | contact inhibition | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0019046 | release from viral latency | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 2 | 2 |
GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0090204 | protein localization to nuclear pore | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0061034 | olfactory bulb mitral cell layer development | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0072092 | ureteric bud invasion | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0002944 | cyclin K-CDK12 complex | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0042826 | histone deacetylase binding | 2.47e-03 | 1.00e+00 | 4.739 | 2 | 4 | 72 |
GO:0006355 | regulation of transcription, DNA-templated | 2.61e-03 | 1.00e+00 | 2.270 | 5 | 43 | 997 |
GO:0060913 | cardiac cell fate determination | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0001650 | fibrillar center | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0050779 | RNA destabilization | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0019908 | nuclear cyclin-dependent protein kinase holoenzyme complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0061198 | fungiform papilla formation | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0021553 | olfactory nerve development | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0001649 | osteoblast differentiation | 4.00e-03 | 1.00e+00 | 4.386 | 2 | 5 | 92 |
GO:0032680 | regulation of tumor necrosis factor production | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0030578 | PML body organization | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0021889 | olfactory bulb interneuron differentiation | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0051726 | regulation of cell cycle | 4.44e-03 | 1.00e+00 | 4.309 | 2 | 5 | 97 |
GO:0003723 | RNA binding | 4.86e-03 | 1.00e+00 | 3.076 | 3 | 18 | 342 |
GO:0070461 | SAGA-type complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 2 | 5 |
GO:0001714 | endodermal cell fate specification | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0019957 | C-C chemokine binding | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 2 | 5 |
GO:0035925 | mRNA 3'-UTR AU-rich region binding | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0043405 | regulation of MAP kinase activity | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0005737 | cytoplasm | 5.73e-03 | 1.00e+00 | 1.200 | 9 | 124 | 3767 |
GO:0050847 | progesterone receptor signaling pathway | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 6 |
GO:0050733 | RS domain binding | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0070937 | CRD-mediated mRNA stability complex | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 3 | 6 |
GO:0060789 | hair follicle placode formation | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 6 |
GO:0019213 | deacetylase activity | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0071354 | cellular response to interleukin-6 | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 2 | 7 |
GO:0003337 | mesenchymal to epithelial transition involved in metanephros morphogenesis | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
GO:0010870 | positive regulation of receptor biosynthetic process | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
GO:2000177 | regulation of neural precursor cell proliferation | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.47e-03 | 1.00e+00 | 2.285 | 4 | 41 | 789 |
GO:0009913 | epidermal cell differentiation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0035137 | hindlimb morphogenesis | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0043254 | regulation of protein complex assembly | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0042473 | outer ear morphogenesis | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0043996 | histone acetyltransferase activity (H4-K8 specific) | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 5 | 9 |
GO:0010832 | negative regulation of myotube differentiation | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0043995 | histone acetyltransferase activity (H4-K5 specific) | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 5 | 9 |
GO:0006476 | protein deacetylation | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0046972 | histone acetyltransferase activity (H4-K16 specific) | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 5 | 9 |
GO:0035278 | negative regulation of translation involved in gene silencing by miRNA | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0048188 | Set1C/COMPASS complex | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 4 | 9 |
GO:0035136 | forelimb morphogenesis | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0010944 | negative regulation of transcription by competitive promoter binding | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0060711 | labyrinthine layer development | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 3 | 9 |
GO:0033558 | protein deacetylase activity | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 10 |
GO:0035413 | positive regulation of catenin import into nucleus | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 10 |
GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 1 | 10 |
GO:0061029 | eyelid development in camera-type eye | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 2 | 10 |
GO:0010369 | chromocenter | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 2 | 11 |
GO:0019789 | SUMO ligase activity | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 4 | 11 |
GO:0006397 | mRNA processing | 1.17e-02 | 1.00e+00 | 3.587 | 2 | 10 | 160 |
GO:0000398 | mRNA splicing, via spliceosome | 1.22e-02 | 1.00e+00 | 3.552 | 2 | 15 | 164 |
GO:0046970 | NAD-dependent histone deacetylase activity (H4-K16 specific) | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0006402 | mRNA catabolic process | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 12 |
GO:0016580 | Sin3 complex | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0043922 | negative regulation by host of viral transcription | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0097372 | NAD-dependent histone deacetylase activity (H3-K18 specific) | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0032041 | NAD-dependent histone deacetylase activity (H3-K14 specific) | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
GO:0061647 | histone H3-K9 modification | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 2 | 13 |
GO:0046969 | NAD-dependent histone deacetylase activity (H3-K9 specific) | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
GO:0031334 | positive regulation of protein complex assembly | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 2 | 13 |
GO:0031625 | ubiquitin protein ligase binding | 1.43e-02 | 1.00e+00 | 3.433 | 2 | 5 | 178 |
GO:0003714 | transcription corepressor activity | 1.43e-02 | 1.00e+00 | 3.433 | 2 | 11 | 178 |
GO:0003281 | ventricular septum development | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 14 |
GO:0031011 | Ino80 complex | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 6 | 14 |
GO:0048566 | embryonic digestive tract development | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 1 | 14 |
GO:0017091 | AU-rich element binding | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 14 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.52e-02 | 1.00e+00 | 3.386 | 2 | 22 | 184 |
GO:0043981 | histone H4-K5 acetylation | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 5 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 3 | 15 |
GO:0001824 | blastocyst development | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 2 | 15 |
GO:0043982 | histone H4-K8 acetylation | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 5 | 15 |
GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0060173 | limb development | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0043274 | phospholipase binding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0060334 | regulation of interferon-gamma-mediated signaling pathway | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0045638 | negative regulation of myeloid cell differentiation | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0001829 | trophectodermal cell differentiation | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 2 | 17 |
GO:0070933 | histone H4 deacetylation | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 1 | 17 |
GO:0030332 | cyclin binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 18 |
GO:0071889 | 14-3-3 protein binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 18 |
GO:0033613 | activating transcription factor binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 3 | 18 |
GO:0043984 | histone H4-K16 acetylation | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 5 | 19 |
GO:0001106 | RNA polymerase II transcription corepressor activity | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 2 | 21 |
GO:0030325 | adrenal gland development | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 1 | 21 |
GO:0000123 | histone acetyltransferase complex | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 6 | 21 |
GO:0070932 | histone H3 deacetylation | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 2 | 21 |
GO:0043484 | regulation of RNA splicing | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 1 | 22 |
GO:0000792 | heterochromatin | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 1 | 22 |
GO:0045787 | positive regulation of cell cycle | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 2 | 22 |
GO:0045879 | negative regulation of smoothened signaling pathway | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 2 | 22 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 2 | 23 |
GO:0003713 | transcription coactivator activity | 2.45e-02 | 1.00e+00 | 3.020 | 2 | 24 | 237 |
GO:0000794 | condensed nuclear chromosome | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 24 |
GO:0016925 | protein sumoylation | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 2 | 25 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 3 | 25 |
GO:0008406 | gonad development | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 1 | 25 |
GO:0035329 | hippo signaling | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 5 | 26 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 3 | 26 |
GO:0043392 | negative regulation of DNA binding | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 4 | 26 |
GO:0030177 | positive regulation of Wnt signaling pathway | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 1 | 27 |
GO:0001103 | RNA polymerase II repressing transcription factor binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 2 | 27 |
GO:0021983 | pituitary gland development | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 2 | 27 |
GO:0045597 | positive regulation of cell differentiation | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 1 | 27 |
GO:0071339 | MLL1 complex | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 6 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 2 | 27 |
GO:0003727 | single-stranded RNA binding | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 2 | 28 |
GO:0070491 | repressing transcription factor binding | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 2 | 28 |
GO:0000118 | histone deacetylase complex | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
GO:0071897 | DNA biosynthetic process | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
GO:0006281 | DNA repair | 2.93e-02 | 1.00e+00 | 2.881 | 2 | 14 | 261 |
GO:0008333 | endosome to lysosome transport | 2.98e-02 | 1.00e+00 | 5.051 | 1 | 2 | 29 |
GO:0010494 | cytoplasmic stress granule | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 30 |
GO:0004693 | cyclin-dependent protein serine/threonine kinase activity | 3.18e-02 | 1.00e+00 | 4.955 | 1 | 1 | 31 |
GO:0042594 | response to starvation | 3.18e-02 | 1.00e+00 | 4.955 | 1 | 4 | 31 |
GO:0019899 | enzyme binding | 3.27e-02 | 1.00e+00 | 2.795 | 2 | 9 | 277 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 2 | 32 |
GO:0001568 | blood vessel development | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 2 | 35 |
GO:0032880 | regulation of protein localization | 3.78e-02 | 1.00e+00 | 4.700 | 1 | 2 | 37 |
GO:0001657 | ureteric bud development | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 2 | 38 |
GO:0045786 | negative regulation of cell cycle | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 3 | 39 |
GO:0031124 | mRNA 3'-end processing | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 2 | 42 |
GO:0001658 | branching involved in ureteric bud morphogenesis | 4.38e-02 | 1.00e+00 | 4.483 | 1 | 3 | 43 |
GO:0003682 | chromatin binding | 4.43e-02 | 1.00e+00 | 2.556 | 2 | 19 | 327 |
GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 44 |
GO:0001047 | core promoter binding | 4.58e-02 | 1.00e+00 | 4.417 | 1 | 5 | 45 |
GO:0006369 | termination of RNA polymerase II transcription | 4.58e-02 | 1.00e+00 | 4.417 | 1 | 2 | 45 |
GO:0043565 | sequence-specific DNA binding | 4.90e-02 | 1.00e+00 | 2.475 | 2 | 11 | 346 |
GO:0032922 | circadian regulation of gene expression | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 1 | 49 |
GO:0000910 | cytokinesis | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 2 | 51 |
GO:0017053 | transcriptional repressor complex | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 2 | 51 |
GO:0000226 | microtubule cytoskeleton organization | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 2 | 52 |
GO:0009611 | response to wounding | 5.28e-02 | 1.00e+00 | 4.209 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 5 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 4 | 53 |
GO:0042475 | odontogenesis of dentin-containing tooth | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 1 | 55 |
GO:0050728 | negative regulation of inflammatory response | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 3 | 56 |
GO:0005643 | nuclear pore | 5.77e-02 | 1.00e+00 | 4.076 | 1 | 11 | 57 |
GO:0008284 | positive regulation of cell proliferation | 5.85e-02 | 1.00e+00 | 2.332 | 2 | 10 | 382 |
GO:0006396 | RNA processing | 5.97e-02 | 1.00e+00 | 4.027 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.97e-02 | 1.00e+00 | 4.027 | 1 | 6 | 59 |
GO:0008013 | beta-catenin binding | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 9 | 60 |
GO:0006406 | mRNA export from nucleus | 6.16e-02 | 1.00e+00 | 3.978 | 1 | 4 | 61 |
GO:0060333 | interferon-gamma-mediated signaling pathway | 6.26e-02 | 1.00e+00 | 3.955 | 1 | 3 | 62 |
GO:0045666 | positive regulation of neuron differentiation | 6.36e-02 | 1.00e+00 | 3.932 | 1 | 3 | 63 |
GO:0006310 | DNA recombination | 6.55e-02 | 1.00e+00 | 3.887 | 1 | 7 | 65 |
GO:0006338 | chromatin remodeling | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 3 | 66 |
GO:0010468 | regulation of gene expression | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 2 | 68 |
GO:0043066 | negative regulation of apoptotic process | 7.03e-02 | 1.00e+00 | 2.181 | 2 | 16 | 424 |
GO:0060021 | palate development | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 1 | 72 |
GO:0003729 | mRNA binding | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 4 | 72 |
GO:0000785 | chromatin | 7.33e-02 | 1.00e+00 | 3.719 | 1 | 6 | 73 |
GO:0002020 | protease binding | 7.43e-02 | 1.00e+00 | 3.700 | 1 | 6 | 74 |
GO:0001843 | neural tube closure | 7.43e-02 | 1.00e+00 | 3.700 | 1 | 2 | 74 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 7.43e-02 | 1.00e+00 | 3.700 | 1 | 4 | 74 |
GO:0001822 | kidney development | 7.82e-02 | 1.00e+00 | 3.624 | 1 | 3 | 78 |
GO:0071013 | catalytic step 2 spliceosome | 7.82e-02 | 1.00e+00 | 3.624 | 1 | 7 | 78 |
GO:0009653 | anatomical structure morphogenesis | 8.30e-02 | 1.00e+00 | 3.534 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 8.30e-02 | 1.00e+00 | 3.534 | 1 | 4 | 83 |
GO:0009887 | organ morphogenesis | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 5 | 86 |
GO:0003690 | double-stranded DNA binding | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 3 | 86 |
GO:0050821 | protein stabilization | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 3 | 88 |
GO:0016605 | PML body | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 3 | 88 |
GO:0016568 | chromatin modification | 9.73e-02 | 1.00e+00 | 3.294 | 1 | 4 | 98 |
GO:0003676 | nucleic acid binding | 1.06e-01 | 1.00e+00 | 3.168 | 1 | 2 | 107 |
GO:0030308 | negative regulation of cell growth | 1.09e-01 | 1.00e+00 | 3.128 | 1 | 6 | 110 |
GO:0030529 | ribonucleoprotein complex | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 5 | 112 |
GO:0006325 | chromatin organization | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 12 | 118 |
GO:0007219 | Notch signaling pathway | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 5 | 120 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.25e-01 | 1.00e+00 | 2.909 | 1 | 11 | 128 |
GO:0000790 | nuclear chromatin | 1.26e-01 | 1.00e+00 | 2.898 | 1 | 6 | 129 |
GO:0045202 | synapse | 1.33e-01 | 1.00e+00 | 2.822 | 1 | 5 | 136 |
GO:0007507 | heart development | 1.35e-01 | 1.00e+00 | 2.790 | 1 | 7 | 139 |
GO:0010628 | positive regulation of gene expression | 1.42e-01 | 1.00e+00 | 2.719 | 1 | 7 | 146 |
GO:0042981 | regulation of apoptotic process | 1.45e-01 | 1.00e+00 | 2.680 | 1 | 4 | 150 |
GO:0006974 | cellular response to DNA damage stimulus | 1.46e-01 | 1.00e+00 | 2.671 | 1 | 7 | 151 |
GO:0046872 | metal ion binding | 1.49e-01 | 1.00e+00 | 1.142 | 3 | 29 | 1307 |
GO:0046777 | protein autophosphorylation | 1.52e-01 | 1.00e+00 | 2.605 | 1 | 4 | 158 |
GO:0043687 | post-translational protein modification | 1.56e-01 | 1.00e+00 | 2.569 | 1 | 5 | 162 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.59e-01 | 1.00e+00 | 2.543 | 1 | 12 | 165 |
GO:0031965 | nuclear membrane | 1.61e-01 | 1.00e+00 | 2.517 | 1 | 10 | 168 |
GO:0005667 | transcription factor complex | 1.67e-01 | 1.00e+00 | 2.458 | 1 | 17 | 175 |
GO:0007049 | cell cycle | 1.67e-01 | 1.00e+00 | 2.466 | 1 | 6 | 174 |
GO:0004672 | protein kinase activity | 1.69e-01 | 1.00e+00 | 2.442 | 1 | 3 | 177 |
GO:0019221 | cytokine-mediated signaling pathway | 2.07e-01 | 1.00e+00 | 2.121 | 1 | 8 | 221 |
GO:0016071 | mRNA metabolic process | 2.09e-01 | 1.00e+00 | 2.108 | 1 | 8 | 223 |
GO:0030425 | dendrite | 2.14e-01 | 1.00e+00 | 2.064 | 1 | 6 | 230 |
GO:0043025 | neuronal cell body | 2.27e-01 | 1.00e+00 | 1.973 | 1 | 9 | 245 |
GO:0016070 | RNA metabolic process | 2.28e-01 | 1.00e+00 | 1.961 | 1 | 8 | 247 |
GO:0000166 | nucleotide binding | 2.38e-01 | 1.00e+00 | 1.892 | 1 | 13 | 259 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.46e-01 | 1.00e+00 | 1.838 | 1 | 7 | 269 |
GO:0016020 | membrane | 2.51e-01 | 1.00e+00 | 0.779 | 3 | 46 | 1681 |
GO:0005743 | mitochondrial inner membrane | 2.53e-01 | 1.00e+00 | 1.795 | 1 | 6 | 277 |
GO:0006954 | inflammatory response | 2.53e-01 | 1.00e+00 | 1.795 | 1 | 6 | 277 |
GO:0005829 | cytosol | 2.54e-01 | 1.00e+00 | 0.624 | 4 | 86 | 2496 |
GO:0043234 | protein complex | 2.67e-01 | 1.00e+00 | 1.705 | 1 | 11 | 295 |
GO:0035556 | intracellular signal transduction | 2.73e-01 | 1.00e+00 | 1.666 | 1 | 9 | 303 |
GO:0005739 | mitochondrion | 2.79e-01 | 1.00e+00 | 0.946 | 2 | 23 | 998 |
GO:0019901 | protein kinase binding | 2.84e-01 | 1.00e+00 | 1.601 | 1 | 18 | 317 |
GO:0008283 | cell proliferation | 2.92e-01 | 1.00e+00 | 1.552 | 1 | 14 | 328 |
GO:0008285 | negative regulation of cell proliferation | 3.11e-01 | 1.00e+00 | 1.446 | 1 | 10 | 353 |
GO:0000278 | mitotic cell cycle | 3.38e-01 | 1.00e+00 | 1.298 | 1 | 15 | 391 |
GO:0009986 | cell surface | 3.46e-01 | 1.00e+00 | 1.258 | 1 | 9 | 402 |
GO:0007596 | blood coagulation | 3.82e-01 | 1.00e+00 | 1.079 | 1 | 11 | 455 |
GO:0044267 | cellular protein metabolic process | 3.94e-01 | 1.00e+00 | 1.020 | 1 | 20 | 474 |
GO:0005524 | ATP binding | 3.97e-01 | 1.00e+00 | 0.567 | 2 | 31 | 1298 |
GO:0042802 | identical protein binding | 4.01e-01 | 1.00e+00 | 0.990 | 1 | 19 | 484 |
GO:0016032 | viral process | 4.32e-01 | 1.00e+00 | 0.848 | 1 | 26 | 534 |
GO:0006351 | transcription, DNA-templated | 4.52e-01 | 1.00e+00 | 0.411 | 2 | 57 | 1446 |
GO:0005887 | integral component of plasma membrane | 6.15e-01 | 1.00e+00 | 0.115 | 1 | 10 | 888 |
GO:0007165 | signal transduction | 6.23e-01 | 1.00e+00 | 0.084 | 1 | 13 | 907 |
GO:0070062 | extracellular vesicular exosome | 9.35e-01 | 1.00e+00 | -1.320 | 1 | 57 | 2400 |