Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.797 | 4.17e-15 | 7.53e-04 | 4.63e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
HCFC1 | 3054 | 40 | -2.925 | 3.449 | 71 | Yes | Yes |
TUBB4A | 10382 | 7 | -2.312 | 2.975 | 88 | Yes | - |
ZFP36 | 7538 | 10 | -2.968 | 2.869 | 24 | Yes | Yes |
NFKB1 | 4790 | 9 | -2.123 | 2.870 | 263 | Yes | - |
[ GDPD2 ] | 54857 | 1 | -1.255 | 2.797 | 4 | - | - |
HEXDC | 284004 | 1 | -1.478 | 2.797 | 10 | - | - |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
SRSF3 | 6428 | 73 | -2.992 | 3.538 | 54 | Yes | - |
NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
MAP3K1 | 4214 | 3 | -2.088 | 2.975 | 123 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
TUBB4A | 10382 | HEXDC | 284004 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
HCFC1 | 3054 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
NFKB1 | 4790 | ZFP36 | 7538 | pp | -- | int.I2D: BioGrid |
DDIT3 | 1649 | NFKB1 | 4790 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
NFKB1 | 4790 | TUBB4A | 10382 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
POU5F1 | 5460 | TUBB4A | 10382 | pp | -- | int.I2D: BioGrid |
DDIT3 | 1649 | TUBB4A | 10382 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
MAP3K1 | 4214 | TUBB4A | 10382 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT; int.Mint: MI:0915(physical association) |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
GDPD2 | 54857 | HEXDC | 284004 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, MINT, StelzlMedium, HPRD, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
NFKB1 | 4790 | NFRKB | 4798 | pp | -- | int.I2D: BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0044212 | transcription regulatory region DNA binding | 1.17e-05 | 1.69e-01 | 4.723 | 4 | 17 | 168 |
GO:0005654 | nucleoplasm | 1.51e-05 | 2.17e-01 | 2.844 | 7 | 64 | 1082 |
GO:0006366 | transcription from RNA polymerase II promoter | 2.14e-05 | 3.09e-01 | 3.727 | 5 | 30 | 419 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 5.82e-05 | 8.39e-01 | 7.415 | 2 | 2 | 13 |
GO:0042594 | response to starvation | 3.44e-04 | 1.00e+00 | 6.161 | 2 | 4 | 31 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0047394 | glycerophosphoinositol inositolphosphodiesterase activity | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0045083 | negative regulation of interleukin-12 biosynthetic process | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0005634 | nucleus | 1.03e-03 | 1.00e+00 | 1.283 | 10 | 159 | 4559 |
GO:0050728 | negative regulation of inflammatory response | 1.12e-03 | 1.00e+00 | 5.308 | 2 | 3 | 56 |
GO:0008134 | transcription factor binding | 1.18e-03 | 1.00e+00 | 3.782 | 3 | 18 | 242 |
GO:0006355 | regulation of transcription, DNA-templated | 1.26e-03 | 1.00e+00 | 2.476 | 5 | 43 | 997 |
GO:0034146 | toll-like receptor 5 signaling pathway | 1.51e-03 | 1.00e+00 | 5.093 | 2 | 4 | 65 |
GO:0071260 | cellular response to mechanical stimulus | 1.51e-03 | 1.00e+00 | 5.093 | 2 | 4 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 1.51e-03 | 1.00e+00 | 5.093 | 2 | 4 | 65 |
GO:0060242 | contact inhibition | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 1.80e-03 | 1.00e+00 | 4.966 | 2 | 4 | 71 |
GO:0019046 | release from viral latency | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 2 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 1.80e-03 | 1.00e+00 | 4.966 | 2 | 4 | 71 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0034162 | toll-like receptor 9 signaling pathway | 1.85e-03 | 1.00e+00 | 4.946 | 2 | 4 | 72 |
GO:0034134 | toll-like receptor 2 signaling pathway | 1.90e-03 | 1.00e+00 | 4.926 | 2 | 4 | 73 |
GO:0005515 | protein binding | 2.00e-03 | 1.00e+00 | 1.019 | 11 | 198 | 6024 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 2.28e-03 | 1.00e+00 | 4.794 | 2 | 5 | 80 |
GO:0010467 | gene expression | 2.34e-03 | 1.00e+00 | 2.730 | 4 | 45 | 669 |
GO:0004563 | beta-N-acetylhexosaminidase activity | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0033256 | I-kappaB/NF-kappaB complex | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0008889 | glycerophosphodiester phosphodiesterase activity | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0008545 | JUN kinase kinase activity | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:1900127 | positive regulation of hyaluronan biosynthetic process | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0050779 | RNA destabilization | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 2.75e-03 | 1.00e+00 | 2.666 | 4 | 39 | 699 |
GO:0005829 | cytosol | 2.99e-03 | 1.00e+00 | 1.638 | 7 | 86 | 2496 |
GO:0003677 | DNA binding | 3.08e-03 | 1.00e+00 | 2.187 | 5 | 49 | 1218 |
GO:0034142 | toll-like receptor 4 signaling pathway | 3.26e-03 | 1.00e+00 | 4.531 | 2 | 4 | 96 |
GO:0032680 | regulation of tumor necrosis factor production | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0010957 | negative regulation of vitamin D biosynthetic process | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0032375 | negative regulation of cholesterol transport | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0032269 | negative regulation of cellular protein metabolic process | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:2000630 | positive regulation of miRNA metabolic process | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0033269 | internode region of axon | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0002224 | toll-like receptor signaling pathway | 4.18e-03 | 1.00e+00 | 4.347 | 2 | 4 | 109 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 4.27e-03 | 1.00e+00 | 2.492 | 4 | 41 | 789 |
GO:0070461 | SAGA-type complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 2 | 5 |
GO:0001714 | endodermal cell fate specification | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0019957 | C-C chemokine binding | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 2 | 5 |
GO:0010884 | positive regulation of lipid storage | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0035925 | mRNA 3'-UTR AU-rich region binding | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0070937 | CRD-mediated mRNA stability complex | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 3 | 6 |
GO:0071354 | cellular response to interleukin-6 | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 2 | 7 |
GO:0001955 | blood vessel maturation | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0071316 | cellular response to nicotine | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0043254 | regulation of protein complex assembly | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0005737 | cytoplasm | 7.50e-03 | 1.00e+00 | 1.236 | 8 | 124 | 3767 |
GO:0006974 | cellular response to DNA damage stimulus | 7.87e-03 | 1.00e+00 | 3.877 | 2 | 7 | 151 |
GO:0043995 | histone acetyltransferase activity (H4-K5 specific) | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 5 | 9 |
GO:0046972 | histone acetyltransferase activity (H4-K16 specific) | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 5 | 9 |
GO:0035278 | negative regulation of translation involved in gene silencing by miRNA | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0048188 | Set1C/COMPASS complex | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 4 | 9 |
GO:0006983 | ER overload response | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0003382 | epithelial cell morphogenesis | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0000975 | regulatory region DNA binding | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 9 |
GO:0043996 | histone acetyltransferase activity (H4-K8 specific) | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 5 | 9 |
GO:0006071 | glycerol metabolic process | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0035413 | positive regulation of catenin import into nucleus | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 2 | 10 |
GO:0061029 | eyelid development in camera-type eye | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 2 | 10 |
GO:1900153 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 2 | 10 |
GO:0000398 | mRNA splicing, via spliceosome | 9.23e-03 | 1.00e+00 | 3.758 | 2 | 15 | 164 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 9.67e-03 | 1.00e+00 | 3.723 | 2 | 5 | 168 |
GO:0045662 | negative regulation of myoblast differentiation | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 3 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 4 | 11 |
GO:0060213 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 11 |
GO:0006402 | mRNA catabolic process | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0003714 | transcription corepressor activity | 1.08e-02 | 1.00e+00 | 3.640 | 2 | 11 | 178 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 3 | 12 |
GO:0035198 | miRNA binding | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0046688 | response to copper ion | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0044822 | poly(A) RNA binding | 1.20e-02 | 1.00e+00 | 2.071 | 4 | 50 | 1056 |
GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 14 |
GO:0031293 | membrane protein intracellular domain proteolysis | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 14 |
GO:0017091 | AU-rich element binding | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 14 |
GO:0031011 | Ino80 complex | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 6 | 14 |
GO:0071375 | cellular response to peptide hormone stimulus | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 2 | 14 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1.31e-02 | 1.00e+00 | 2.546 | 3 | 37 | 570 |
GO:0043981 | histone H4-K5 acetylation | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 5 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 3 | 15 |
GO:0001824 | blastocyst development | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 2 | 15 |
GO:0043982 | histone H4-K8 acetylation | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 5 | 15 |
GO:0043274 | phospholipase binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0043209 | myelin sheath | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0045638 | negative regulation of myeloid cell differentiation | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0004709 | MAP kinase kinase kinase activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 18 |
GO:0071889 | 14-3-3 protein binding | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 18 |
GO:0043984 | histone H4-K16 acetylation | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 5 | 19 |
GO:0008380 | RNA splicing | 1.73e-02 | 1.00e+00 | 3.283 | 2 | 22 | 228 |
GO:0032757 | positive regulation of interleukin-8 production | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 1 | 20 |
GO:0003713 | transcription coactivator activity | 1.86e-02 | 1.00e+00 | 3.227 | 2 | 24 | 237 |
GO:0000123 | histone acetyltransferase complex | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 6 | 21 |
GO:0008637 | apoptotic mitochondrial changes | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 2 | 21 |
GO:0045787 | positive regulation of cell cycle | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 22 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 4 | 22 |
GO:0043025 | neuronal cell body | 1.98e-02 | 1.00e+00 | 3.179 | 2 | 9 | 245 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 3 | 25 |
GO:0035329 | hippo signaling | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 5 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 1 | 26 |
GO:0000976 | transcription regulatory region sequence-specific DNA binding | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 3 | 26 |
GO:0007017 | microtubule-based process | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 2 | 27 |
GO:0071339 | MLL1 complex | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 6 | 27 |
GO:0051258 | protein polymerization | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 2 | 27 |
GO:0006954 | inflammatory response | 2.49e-02 | 1.00e+00 | 3.002 | 2 | 6 | 277 |
GO:0003727 | single-stranded RNA binding | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 2 | 28 |
GO:0010494 | cytoplasmic stress granule | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 2 | 30 |
GO:0071347 | cellular response to interleukin-1 | 2.76e-02 | 1.00e+00 | 5.161 | 1 | 2 | 31 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 2 | 32 |
GO:0031072 | heat shock protein binding | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 2 | 33 |
GO:0030838 | positive regulation of actin filament polymerization | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 1 | 34 |
GO:0019901 | protein kinase binding | 3.20e-02 | 1.00e+00 | 2.807 | 2 | 18 | 317 |
GO:0007257 | activation of JUN kinase activity | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 5 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.29e-02 | 1.00e+00 | 4.906 | 1 | 5 | 37 |
GO:0035019 | somatic stem cell maintenance | 3.55e-02 | 1.00e+00 | 4.794 | 1 | 6 | 40 |
GO:0003723 | RNA binding | 3.68e-02 | 1.00e+00 | 2.698 | 2 | 18 | 342 |
GO:0031124 | mRNA 3'-end processing | 3.72e-02 | 1.00e+00 | 4.723 | 1 | 2 | 42 |
GO:0043565 | sequence-specific DNA binding | 3.76e-02 | 1.00e+00 | 2.681 | 2 | 11 | 346 |
GO:0006369 | termination of RNA polymerase II transcription | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 2 | 45 |
GO:0043525 | positive regulation of neuron apoptotic process | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 4 | 46 |
GO:0090263 | positive regulation of canonical Wnt signaling pathway | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 3 | 48 |
GO:0006986 | response to unfolded protein | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 4 | 50 |
GO:0030334 | regulation of cell migration | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 5 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 4.50e-02 | 1.00e+00 | 4.443 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 4.50e-02 | 1.00e+00 | 4.443 | 1 | 1 | 51 |
GO:0009611 | response to wounding | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 5 | 52 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 4.68e-02 | 1.00e+00 | 4.388 | 1 | 4 | 53 |
GO:0000186 | activation of MAPKK activity | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 2 | 54 |
GO:0006396 | RNA processing | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 6 | 59 |
GO:0032481 | positive regulation of type I interferon production | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 6 | 61 |
GO:0006406 | mRNA export from nucleus | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 4 | 61 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 5.36e-02 | 1.00e+00 | 4.185 | 1 | 2 | 61 |
GO:0042060 | wound healing | 5.62e-02 | 1.00e+00 | 4.116 | 1 | 2 | 64 |
GO:0006310 | DNA recombination | 5.71e-02 | 1.00e+00 | 4.093 | 1 | 7 | 65 |
GO:0010468 | regulation of gene expression | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 2 | 68 |
GO:0003729 | mRNA binding | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 4 | 72 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 6.47e-02 | 1.00e+00 | 3.906 | 1 | 4 | 74 |
GO:0002020 | protease binding | 6.47e-02 | 1.00e+00 | 3.906 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.56e-02 | 1.00e+00 | 3.887 | 1 | 1 | 75 |
GO:0044267 | cellular protein metabolic process | 6.62e-02 | 1.00e+00 | 2.227 | 2 | 20 | 474 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 6.64e-02 | 1.00e+00 | 3.868 | 1 | 3 | 76 |
GO:0045893 | positive regulation of transcription, DNA-templated | 6.72e-02 | 1.00e+00 | 2.215 | 2 | 24 | 478 |
GO:0005929 | cilium | 6.72e-02 | 1.00e+00 | 3.849 | 1 | 2 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 6.81e-02 | 1.00e+00 | 3.830 | 1 | 7 | 78 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 6.81e-02 | 1.00e+00 | 3.830 | 1 | 3 | 78 |
GO:0034138 | toll-like receptor 3 signaling pathway | 6.89e-02 | 1.00e+00 | 3.812 | 1 | 3 | 79 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 6.89e-02 | 1.00e+00 | 3.812 | 1 | 2 | 79 |
GO:0071222 | cellular response to lipopolysaccharide | 7.06e-02 | 1.00e+00 | 3.776 | 1 | 4 | 81 |
GO:0009653 | anatomical structure morphogenesis | 7.23e-02 | 1.00e+00 | 3.741 | 1 | 2 | 83 |
GO:0050852 | T cell receptor signaling pathway | 7.40e-02 | 1.00e+00 | 3.706 | 1 | 2 | 85 |
GO:0003690 | double-stranded DNA binding | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 3 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 8 | 86 |
GO:0006979 | response to oxidative stress | 7.57e-02 | 1.00e+00 | 3.673 | 1 | 6 | 87 |
GO:0050821 | protein stabilization | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 3 | 88 |
GO:0006629 | lipid metabolic process | 7.82e-02 | 1.00e+00 | 3.624 | 1 | 1 | 90 |
GO:0005200 | structural constituent of cytoskeleton | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 6 | 91 |
GO:0001649 | osteoblast differentiation | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 5 | 92 |
GO:0005770 | late endosome | 8.07e-02 | 1.00e+00 | 3.576 | 1 | 2 | 93 |
GO:0030529 | ribonucleoprotein complex | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 5 | 112 |
GO:0045087 | innate immune response | 9.84e-02 | 1.00e+00 | 1.896 | 2 | 15 | 596 |
GO:0006325 | chromatin organization | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 12 | 118 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.06e-01 | 1.00e+00 | 3.161 | 1 | 5 | 124 |
GO:0007050 | cell cycle arrest | 1.06e-01 | 1.00e+00 | 3.161 | 1 | 5 | 124 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.09e-01 | 1.00e+00 | 3.116 | 1 | 11 | 128 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.16e-01 | 1.00e+00 | 3.028 | 1 | 4 | 136 |
GO:0016055 | Wnt signaling pathway | 1.18e-01 | 1.00e+00 | 3.007 | 1 | 4 | 138 |
GO:0006457 | protein folding | 1.22e-01 | 1.00e+00 | 2.956 | 1 | 7 | 143 |
GO:0010628 | positive regulation of gene expression | 1.24e-01 | 1.00e+00 | 2.926 | 1 | 7 | 146 |
GO:0016607 | nuclear speck | 1.44e-01 | 1.00e+00 | 2.689 | 1 | 12 | 172 |
GO:0007049 | cell cycle | 1.46e-01 | 1.00e+00 | 2.673 | 1 | 6 | 174 |
GO:0005667 | transcription factor complex | 1.47e-01 | 1.00e+00 | 2.664 | 1 | 17 | 175 |
GO:0004672 | protein kinase activity | 1.48e-01 | 1.00e+00 | 2.648 | 1 | 3 | 177 |
GO:0031625 | ubiquitin protein ligase binding | 1.49e-01 | 1.00e+00 | 2.640 | 1 | 5 | 178 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.54e-01 | 1.00e+00 | 2.592 | 1 | 22 | 184 |
GO:0003924 | GTPase activity | 1.64e-01 | 1.00e+00 | 2.494 | 1 | 7 | 197 |
GO:0006184 | GTP catabolic process | 1.77e-01 | 1.00e+00 | 2.374 | 1 | 7 | 214 |
GO:0005730 | nucleolus | 1.77e-01 | 1.00e+00 | 1.020 | 3 | 66 | 1641 |
GO:0016071 | mRNA metabolic process | 1.83e-01 | 1.00e+00 | 2.315 | 1 | 8 | 223 |
GO:0016070 | RNA metabolic process | 2.01e-01 | 1.00e+00 | 2.167 | 1 | 8 | 247 |
GO:0005874 | microtubule | 2.03e-01 | 1.00e+00 | 2.156 | 1 | 7 | 249 |
GO:0005975 | carbohydrate metabolic process | 2.06e-01 | 1.00e+00 | 2.133 | 1 | 8 | 253 |
GO:0000166 | nucleotide binding | 2.10e-01 | 1.00e+00 | 2.099 | 1 | 13 | 259 |
GO:0006281 | DNA repair | 2.11e-01 | 1.00e+00 | 2.088 | 1 | 14 | 261 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.17e-01 | 1.00e+00 | 2.044 | 1 | 7 | 269 |
GO:0005739 | mitochondrion | 2.26e-01 | 1.00e+00 | 1.153 | 2 | 23 | 998 |
GO:0005856 | cytoskeleton | 2.33e-01 | 1.00e+00 | 1.931 | 1 | 9 | 291 |
GO:0035556 | intracellular signal transduction | 2.41e-01 | 1.00e+00 | 1.872 | 1 | 9 | 303 |
GO:0005525 | GTP binding | 2.46e-01 | 1.00e+00 | 1.840 | 1 | 12 | 310 |
GO:0003682 | chromatin binding | 2.58e-01 | 1.00e+00 | 1.762 | 1 | 19 | 327 |
GO:0008283 | cell proliferation | 2.59e-01 | 1.00e+00 | 1.758 | 1 | 14 | 328 |
GO:0046982 | protein heterodimerization activity | 2.93e-01 | 1.00e+00 | 1.546 | 1 | 8 | 380 |
GO:0000278 | mitotic cell cycle | 3.01e-01 | 1.00e+00 | 1.505 | 1 | 15 | 391 |
GO:0009986 | cell surface | 3.08e-01 | 1.00e+00 | 1.465 | 1 | 9 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.15e-01 | 1.00e+00 | 1.426 | 1 | 24 | 413 |
GO:0043066 | negative regulation of apoptotic process | 3.22e-01 | 1.00e+00 | 1.388 | 1 | 16 | 424 |
GO:0005524 | ATP binding | 3.29e-01 | 1.00e+00 | 0.774 | 2 | 31 | 1298 |
GO:0046872 | metal ion binding | 3.32e-01 | 1.00e+00 | 0.764 | 2 | 29 | 1307 |
GO:0006468 | protein phosphorylation | 3.44e-01 | 1.00e+00 | 1.270 | 1 | 10 | 460 |
GO:0042802 | identical protein binding | 3.58e-01 | 1.00e+00 | 1.197 | 1 | 19 | 484 |
GO:0006915 | apoptotic process | 4.00e-01 | 1.00e+00 | 0.999 | 1 | 12 | 555 |
GO:0042803 | protein homodimerization activity | 4.22e-01 | 1.00e+00 | 0.899 | 1 | 19 | 595 |
GO:0016020 | membrane | 4.58e-01 | 1.00e+00 | 0.401 | 2 | 46 | 1681 |
GO:0008270 | zinc ion binding | 6.06e-01 | 1.00e+00 | 0.154 | 1 | 27 | 997 |
GO:0016021 | integral component of membrane | 8.54e-01 | 1.00e+00 | -0.837 | 1 | 17 | 1982 |
GO:0070062 | extracellular vesicular exosome | 9.06e-01 | 1.00e+00 | -1.113 | 1 | 57 | 2400 |
GO:0005886 | plasma membrane | 9.23e-01 | 1.00e+00 | -1.219 | 1 | 49 | 2582 |