int-snw-50618

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.079	2.99e-18	1.89e-05	3.41e-04

chia-screen-data-Fav-int-snw-50618 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
MCRS1	10445	14	-2.660	3.079	63	Yes	Yes
SYNCRIP	10492	9	-2.401	3.197	103	Yes	Yes
YAP1	10413	94	-4.256	3.538	53	Yes	-
INO80E	283899	10	-2.663	3.079	20	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
YY1	7528	24	-2.572	3.120	114	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
[ ITSN2 ]	50618	2	-2.012	3.079	50	Yes	-

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
YY1	7528	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
NFRKB	4798	MCRS1	10445	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
SYNCRIP	10492	ITSN2	50618	pp	--	int.I2D: Jorgensen_EphR
HNRNPU	3192	SYNCRIP	10492	pp	--	int.Mint: MI:0915(physical association)
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
YY1	7528	MCRS1	10445	pp	--	int.I2D: BioGrid
NFRKB	4798	YY1	7528	pp	--	int.I2D: BioGrid
MCRS1	10445	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
MCRS1	10445	ITSN2	50618	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NFRKB	4798	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid

Related GO terms (107)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0031011	Ino80 complex	6.98e-11	1.01e-06	8.839	4	6	14
GO:0070934	CRD-mediated mRNA stabilization	3.46e-06	4.99e-02	9.324	2	2	5
GO:0070937	CRD-mediated mRNA stability complex	5.19e-06	7.48e-02	9.061	2	3	6
GO:0006310	DNA recombination	7.20e-06	1.04e-01	6.209	3	7	65
GO:0044212	transcription regulatory region DNA binding	1.24e-04	1.00e+00	4.839	3	17	168
GO:0006355	regulation of transcription, DNA-templated	1.56e-04	1.00e+00	3.007	5	43	997
GO:0005654	nucleoplasm	2.30e-04	1.00e+00	2.889	5	64	1082
GO:0005515	protein binding	3.85e-04	1.00e+00	1.260	9	198	6024
GO:0006281	DNA repair	4.54e-04	1.00e+00	4.203	3	14	261
GO:0006396	RNA processing	5.81e-04	1.00e+00	5.764	2	5	59
GO:0060795	cell fate commitment involved in formation of primary germ layer	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	6.24e-04	1.00e+00	10.646	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	6.24e-04	1.00e+00	10.646	1	1	1
GO:0005634	nucleus	6.43e-04	1.00e+00	1.492	8	159	4559
GO:0003723	RNA binding	9.98e-04	1.00e+00	3.813	3	18	342
GO:0071013	catalytic step 2 spliceosome	1.01e-03	1.00e+00	5.361	2	7	78
GO:0034696	response to prostaglandin F	1.25e-03	1.00e+00	9.646	1	1	2
GO:0009786	regulation of asymmetric cell division	1.25e-03	1.00e+00	9.646	1	1	2
GO:0060242	contact inhibition	1.25e-03	1.00e+00	9.646	1	1	2
GO:0006403	RNA localization	1.25e-03	1.00e+00	9.646	1	1	2
GO:0001649	osteoblast differentiation	1.41e-03	1.00e+00	5.123	2	5	92
GO:0060913	cardiac cell fate determination	1.87e-03	1.00e+00	9.061	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.87e-03	1.00e+00	9.061	1	1	3
GO:0030529	ribonucleoprotein complex	2.08e-03	1.00e+00	4.839	2	5	112
GO:0097452	GAIT complex	2.49e-03	1.00e+00	8.646	1	1	4
GO:0001714	endodermal cell fate specification	3.12e-03	1.00e+00	8.324	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	3.74e-03	1.00e+00	8.061	1	1	6
GO:0006974	cellular response to DNA damage stimulus	3.74e-03	1.00e+00	4.408	2	7	151
GO:0000398	mRNA splicing, via spliceosome	4.39e-03	1.00e+00	4.289	2	15	164
GO:0003677	DNA binding	4.51e-03	1.00e+00	2.396	4	49	1218
GO:0005667	transcription factor complex	4.98e-03	1.00e+00	4.195	2	17	175
GO:0003714	transcription corepressor activity	5.15e-03	1.00e+00	4.170	2	11	178
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0000400	four-way junction DNA binding	5.60e-03	1.00e+00	7.476	1	1	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0010225	response to UV-C	5.60e-03	1.00e+00	7.476	1	2	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0035413	positive regulation of catenin import into nucleus	6.22e-03	1.00e+00	7.324	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	6.85e-03	1.00e+00	7.187	1	4	11
GO:0035198	miRNA binding	7.47e-03	1.00e+00	7.061	1	1	12
GO:0008143	poly(A) binding	7.47e-03	1.00e+00	7.061	1	2	12
GO:0071480	cellular response to gamma radiation	8.09e-03	1.00e+00	6.946	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	8.09e-03	1.00e+00	6.946	1	2	13
GO:0008380	RNA splicing	8.32e-03	1.00e+00	3.813	2	22	228
GO:0003713	transcription coactivator activity	8.97e-03	1.00e+00	3.757	2	24	237
GO:0043981	histone H4-K5 acetylation	9.32e-03	1.00e+00	6.739	1	5	15
GO:0001824	blastocyst development	9.32e-03	1.00e+00	6.739	1	2	15
GO:0043982	histone H4-K8 acetylation	9.32e-03	1.00e+00	6.739	1	5	15
GO:0048593	camera-type eye morphogenesis	9.94e-03	1.00e+00	6.646	1	1	16
GO:0051276	chromosome organization	9.94e-03	1.00e+00	6.646	1	2	16
GO:0043984	histone H4-K16 acetylation	1.18e-02	1.00e+00	6.398	1	5	19
GO:0000123	histone acetyltransferase complex	1.30e-02	1.00e+00	6.254	1	6	21
GO:0036464	cytoplasmic ribonucleoprotein granule	1.36e-02	1.00e+00	6.187	1	2	22
GO:0071346	cellular response to interferon-gamma	1.43e-02	1.00e+00	6.123	1	1	23
GO:0031519	PcG protein complex	1.55e-02	1.00e+00	6.002	1	1	25
GO:0035329	hippo signaling	1.61e-02	1.00e+00	5.946	1	5	26
GO:0071339	MLL1 complex	1.67e-02	1.00e+00	5.891	1	6	27
GO:0034644	cellular response to UV	1.86e-02	1.00e+00	5.739	1	1	30
GO:1903507	negative regulation of nucleic acid-templated transcription	1.98e-02	1.00e+00	5.646	1	2	32
GO:0044822	poly(A) RNA binding	2.35e-02	1.00e+00	2.187	3	50	1056
GO:0035019	somatic stem cell maintenance	2.47e-02	1.00e+00	5.324	1	6	40
GO:0017148	negative regulation of translation	2.47e-02	1.00e+00	5.324	1	2	40
GO:0006366	transcription from RNA polymerase II promoter	2.65e-02	1.00e+00	2.935	2	30	419
GO:0005070	SH3/SH2 adaptor activity	2.96e-02	1.00e+00	5.061	1	2	48
GO:0009611	response to wounding	3.20e-02	1.00e+00	4.946	1	5	52
GO:0000724	double-strand break repair via homologous recombination	3.38e-02	1.00e+00	4.865	1	2	55
GO:0009967	positive regulation of signal transduction	3.44e-02	1.00e+00	4.839	1	1	56
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	3.62e-02	1.00e+00	4.764	1	5	59
GO:0005089	Rho guanyl-nucleotide exchange factor activity	3.62e-02	1.00e+00	4.764	1	1	59
GO:0010468	regulation of gene expression	4.17e-02	1.00e+00	4.559	1	2	68
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.53e-02	1.00e+00	4.437	1	4	74
GO:0002020	protease binding	4.53e-02	1.00e+00	4.437	1	6	74
GO:0032321	positive regulation of Rho GTPase activity	5.00e-02	1.00e+00	4.289	1	1	82
GO:0009653	anatomical structure morphogenesis	5.06e-02	1.00e+00	4.271	1	2	83
GO:0009952	anterior/posterior pattern specification	5.06e-02	1.00e+00	4.271	1	4	83
GO:0006464	cellular protein modification process	5.12e-02	1.00e+00	4.254	1	4	84
GO:0006351	transcription, DNA-templated	5.33e-02	1.00e+00	1.733	3	57	1446
GO:0016363	nuclear matrix	5.54e-02	1.00e+00	4.138	1	6	91
GO:0010467	gene expression	6.23e-02	1.00e+00	2.260	2	45	669
GO:0006897	endocytosis	6.43e-02	1.00e+00	3.918	1	7	106
GO:0003700	sequence-specific DNA binding transcription factor activity	6.73e-02	1.00e+00	2.197	2	39	699
GO:0006325	chromatin organization	7.13e-02	1.00e+00	3.764	1	12	118
GO:0005730	nucleolus	7.30e-02	1.00e+00	1.551	3	66	1641
GO:0006260	DNA replication	7.30e-02	1.00e+00	3.727	1	3	121
GO:0031625	ubiquitin protein ligase binding	1.06e-01	1.00e+00	3.170	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.09e-01	1.00e+00	3.123	1	22	184
GO:0008134	transcription factor binding	1.41e-01	1.00e+00	2.727	1	18	242
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.629	1	13	259
GO:0007283	spermatogenesis	1.52e-01	1.00e+00	2.613	1	3	262
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.53e-01	1.00e+00	2.602	1	23	264
GO:0006954	inflammatory response	1.60e-01	1.00e+00	2.532	1	6	277
GO:0030154	cell differentiation	1.73e-01	1.00e+00	2.413	1	5	301
GO:0005737	cytoplasm	1.87e-01	1.00e+00	0.767	4	124	3767
GO:0008283	cell proliferation	1.87e-01	1.00e+00	2.289	1	14	328
GO:0043565	sequence-specific DNA binding	1.96e-01	1.00e+00	2.212	1	11	346
GO:0009986	cell surface	2.25e-01	1.00e+00	1.995	1	9	402
GO:0016020	membrane	2.83e-01	1.00e+00	0.931	2	46	1681
GO:0005509	calcium ion binding	2.87e-01	1.00e+00	1.594	1	11	531
GO:0016032	viral process	2.88e-01	1.00e+00	1.585	1	26	534
GO:0005783	endoplasmic reticulum	2.98e-01	1.00e+00	1.527	1	13	556
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.04e-01	1.00e+00	1.491	1	37	570
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.97e-01	1.00e+00	1.022	1	41	789
GO:0008270	zinc ion binding	4.75e-01	1.00e+00	0.685	1	27	997
GO:0005829	cytosol	4.79e-01	1.00e+00	0.361	2	86	2496
GO:0005524	ATP binding	5.72e-01	1.00e+00	0.304	1	31	1298
GO:0070062	extracellular vesicular exosome	8.06e-01	1.00e+00	-0.583	1	57	2400

chia-Fav

int-snw-50618

Statistics

Genes (9)

Interactions (12)

Related GO terms (107)