int-snw-116113

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.873	6.48e-16	3.06e-04	2.45e-03

chia-screen-data-Fav-int-snw-116113 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
[ FOXP4 ]	116113	1	-0.722	2.873	4	-	-
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
DEGS1	8560	1	-0.943	2.873	13	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
DEGS1	8560	FOXP4	116113	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct
POU5F1	5460	FOXP4	116113	pp	--	int.I2D: BioGrid_Mouse
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse

Related GO terms (114)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006366	transcription from RNA polymerase II promoter	4.48e-05	6.46e-01	4.105	4	30	419
GO:0005654	nucleoplasm	1.09e-04	1.00e+00	3.059	5	64	1082
GO:0060795	cell fate commitment involved in formation of primary germ layer	5.55e-04	1.00e+00	10.816	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	5.55e-04	1.00e+00	10.816	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	5.55e-04	1.00e+00	10.816	1	1	1
GO:1901250	negative regulation of lung goblet cell differentiation	5.55e-04	1.00e+00	10.816	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	5.55e-04	1.00e+00	10.816	1	1	1
GO:0061140	lung secretory cell differentiation	5.55e-04	1.00e+00	10.816	1	1	1
GO:0019046	release from viral latency	1.11e-03	1.00e+00	9.816	1	2	2
GO:0009786	regulation of asymmetric cell division	1.11e-03	1.00e+00	9.816	1	1	2
GO:0060242	contact inhibition	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006355	regulation of transcription, DNA-templated	1.27e-03	1.00e+00	2.855	4	43	997
GO:0060913	cardiac cell fate determination	1.66e-03	1.00e+00	9.231	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.66e-03	1.00e+00	9.231	1	1	3
GO:0006636	unsaturated fatty acid biosynthetic process	2.22e-03	1.00e+00	8.816	1	1	4
GO:0070461	SAGA-type complex	2.77e-03	1.00e+00	8.494	1	2	5
GO:0001714	endodermal cell fate specification	2.77e-03	1.00e+00	8.494	1	1	5
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2.77e-03	1.00e+00	8.494	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	2.77e-03	1.00e+00	8.494	1	2	5
GO:0070937	CRD-mediated mRNA stability complex	3.32e-03	1.00e+00	8.231	1	3	6
GO:0000398	mRNA splicing, via spliceosome	3.44e-03	1.00e+00	4.459	2	15	164
GO:0044212	transcription regulatory region DNA binding	3.61e-03	1.00e+00	4.424	2	17	168
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0043254	regulation of protein complex assembly	4.43e-03	1.00e+00	7.816	1	1	8
GO:0010467	gene expression	4.67e-03	1.00e+00	3.015	3	45	669
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	4.98e-03	1.00e+00	7.646	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	4.98e-03	1.00e+00	7.646	1	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	4.98e-03	1.00e+00	7.646	1	5	9
GO:0048188	Set1C/COMPASS complex	4.98e-03	1.00e+00	7.646	1	4	9
GO:0048617	embryonic foregut morphogenesis	5.53e-03	1.00e+00	7.494	1	1	10
GO:0035413	positive regulation of catenin import into nucleus	5.53e-03	1.00e+00	7.494	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	6.09e-03	1.00e+00	7.357	1	4	11
GO:0008380	RNA splicing	6.54e-03	1.00e+00	3.983	2	22	228
GO:0035198	miRNA binding	6.64e-03	1.00e+00	7.231	1	1	12
GO:0003713	transcription coactivator activity	7.05e-03	1.00e+00	3.927	2	24	237
GO:0071480	cellular response to gamma radiation	7.19e-03	1.00e+00	7.116	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	7.19e-03	1.00e+00	7.116	1	2	13
GO:0031011	Ino80 complex	7.74e-03	1.00e+00	7.009	1	6	14
GO:0043981	histone H4-K5 acetylation	8.29e-03	1.00e+00	6.909	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	8.29e-03	1.00e+00	6.909	1	3	15
GO:0001824	blastocyst development	8.29e-03	1.00e+00	6.909	1	2	15
GO:0043982	histone H4-K8 acetylation	8.29e-03	1.00e+00	6.909	1	5	15
GO:0043274	phospholipase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0043984	histone H4-K16 acetylation	1.05e-02	1.00e+00	6.568	1	5	19
GO:0000123	histone acetyltransferase complex	1.16e-02	1.00e+00	6.424	1	6	21
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	2	22
GO:0045787	positive regulation of cell cycle	1.21e-02	1.00e+00	6.357	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.21e-02	1.00e+00	6.357	1	4	22
GO:0030148	sphingolipid biosynthetic process	1.43e-02	1.00e+00	6.116	1	1	26
GO:0035329	hippo signaling	1.43e-02	1.00e+00	6.116	1	5	26
GO:0003723	RNA binding	1.43e-02	1.00e+00	3.398	2	18	342
GO:0071339	MLL1 complex	1.49e-02	1.00e+00	6.061	1	6	27
GO:0005634	nucleus	1.49e-02	1.00e+00	1.247	6	159	4559
GO:0044822	poly(A) RNA binding	1.66e-02	1.00e+00	2.357	3	50	1056
GO:1903507	negative regulation of nucleic acid-templated transcription	1.76e-02	1.00e+00	5.816	1	2	32
GO:0035019	somatic stem cell maintenance	2.20e-02	1.00e+00	5.494	1	6	40
GO:0031124	mRNA 3'-end processing	2.31e-02	1.00e+00	5.424	1	2	42
GO:0003677	DNA binding	2.44e-02	1.00e+00	2.151	3	49	1218
GO:0006369	termination of RNA polymerase II transcription	2.47e-02	1.00e+00	5.324	1	2	45
GO:0009611	response to wounding	2.85e-02	1.00e+00	5.116	1	5	52
GO:0006396	RNA processing	3.23e-02	1.00e+00	4.933	1	5	59
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	3.23e-02	1.00e+00	4.933	1	5	59
GO:0006665	sphingolipid metabolic process	3.28e-02	1.00e+00	4.909	1	1	60
GO:0006406	mRNA export from nucleus	3.33e-02	1.00e+00	4.885	1	4	61
GO:0009055	electron carrier activity	3.55e-02	1.00e+00	4.794	1	2	65
GO:0006310	DNA recombination	3.55e-02	1.00e+00	4.794	1	7	65
GO:0010468	regulation of gene expression	3.71e-02	1.00e+00	4.729	1	2	68
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.73e-02	1.00e+00	2.661	2	37	570
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.03e-02	1.00e+00	4.607	1	4	74
GO:0002020	protease binding	4.03e-02	1.00e+00	4.607	1	6	74
GO:0071013	catalytic step 2 spliceosome	4.25e-02	1.00e+00	4.531	1	7	78
GO:0009653	anatomical structure morphogenesis	4.51e-02	1.00e+00	4.441	1	2	83
GO:0050821	protein stabilization	4.78e-02	1.00e+00	4.357	1	3	88
GO:0001649	osteoblast differentiation	4.99e-02	1.00e+00	4.293	1	5	92
GO:0003700	sequence-specific DNA binding transcription factor activity	5.41e-02	1.00e+00	2.367	2	39	699
GO:0016020	membrane	5.64e-02	1.00e+00	1.686	3	46	1681
GO:0030529	ribonucleoprotein complex	6.05e-02	1.00e+00	4.009	1	5	112
GO:0005515	protein binding	6.16e-02	1.00e+00	0.845	6	198	6024
GO:0006325	chromatin organization	6.36e-02	1.00e+00	3.933	1	12	118
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.72e-02	1.00e+00	2.192	2	41	789
GO:0007507	heart development	7.46e-02	1.00e+00	3.697	1	7	139
GO:0010628	positive regulation of gene expression	7.82e-02	1.00e+00	3.626	1	7	146
GO:0006974	cellular response to DNA damage stimulus	8.08e-02	1.00e+00	3.578	1	7	151
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.80e-02	1.00e+00	3.450	1	12	165
GO:0016607	nuclear speck	9.15e-02	1.00e+00	3.390	1	12	172
GO:0007049	cell cycle	9.26e-02	1.00e+00	3.373	1	6	174
GO:0005667	transcription factor complex	9.31e-02	1.00e+00	3.365	1	17	175
GO:0031625	ubiquitin protein ligase binding	9.46e-02	1.00e+00	3.340	1	5	178
GO:0003714	transcription corepressor activity	9.46e-02	1.00e+00	3.340	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	9.76e-02	1.00e+00	3.293	1	22	184
GO:0005739	mitochondrion	1.01e-01	1.00e+00	1.853	2	23	998
GO:0008134	transcription factor binding	1.27e-01	1.00e+00	2.897	1	18	242
GO:0043025	neuronal cell body	1.28e-01	1.00e+00	2.879	1	9	245
GO:0005737	cytoplasm	1.30e-01	1.00e+00	0.937	4	124	3767
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.799	1	13	259
GO:0006281	DNA repair	1.36e-01	1.00e+00	2.788	1	14	261
GO:0006954	inflammatory response	1.44e-01	1.00e+00	2.702	1	6	277
GO:0003682	chromatin binding	1.68e-01	1.00e+00	2.463	1	19	327
GO:0008283	cell proliferation	1.68e-01	1.00e+00	2.459	1	14	328
GO:0043565	sequence-specific DNA binding	1.77e-01	1.00e+00	2.381	1	11	346
GO:0046982	protein heterodimerization activity	1.92e-01	1.00e+00	2.246	1	8	380
GO:0009986	cell surface	2.02e-01	1.00e+00	2.165	1	9	402
GO:0055114	oxidation-reduction process	2.11e-01	1.00e+00	2.102	1	10	420
GO:0005730	nucleolus	2.29e-01	1.00e+00	1.136	2	66	1641
GO:0042802	identical protein binding	2.39e-01	1.00e+00	1.897	1	19	484
GO:0005783	endoplasmic reticulum	2.70e-01	1.00e+00	1.697	1	13	556
GO:0005789	endoplasmic reticulum membrane	2.76e-01	1.00e+00	1.661	1	9	570
GO:0042803	protein homodimerization activity	2.86e-01	1.00e+00	1.599	1	19	595
GO:0005887	integral component of plasma membrane	3.99e-01	1.00e+00	1.022	1	10	888
GO:0005829	cytosol	4.15e-01	1.00e+00	0.531	2	86	2496
GO:0044281	small molecule metabolic process	5.04e-01	1.00e+00	0.574	1	20	1211
GO:0005524	ATP binding	5.30e-01	1.00e+00	0.474	1	31	1298
GO:0046872	metal ion binding	5.32e-01	1.00e+00	0.464	1	29	1307
GO:0006351	transcription, DNA-templated	5.71e-01	1.00e+00	0.318	1	57	1446

chia-Fav

int-snw-116113

Statistics

Genes (8)

Interactions (7)

Related GO terms (114)