Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.789 | 5.18e-15 | 8.34e-04 | 4.99e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
HCFC1 | 3054 | 40 | -2.925 | 3.449 | 71 | Yes | Yes |
[ CHGB ] | 1114 | 1 | -1.440 | 2.789 | 31 | - | - |
LARS | 51520 | 14 | -2.574 | 3.157 | 105 | Yes | Yes |
MED19 | 219541 | 30 | -2.657 | 3.449 | 115 | Yes | - |
POLR2L | 5441 | 2 | -1.972 | 3.159 | 63 | - | - |
MED28 | 80306 | 16 | -2.404 | 3.216 | 80 | Yes | - |
POLR2D | 5433 | 3 | -1.998 | 3.216 | 36 | - | - |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
APLP2 | 334 | 12 | -2.732 | 3.206 | 35 | Yes | Yes |
PSMD2 | 5708 | 47 | -4.172 | 3.157 | 386 | Yes | Yes |
EIF2S2 | 8894 | 9 | -2.999 | 2.968 | 81 | Yes | Yes |
EIF2S3 | 1968 | 1 | -1.940 | 2.789 | 198 | - | - |
LUC7L3 | 51747 | 33 | -3.523 | 3.449 | 18 | Yes | - |
POLR2E | 5434 | 4 | -2.037 | 3.157 | 115 | Yes | - |
MED12 | 9968 | 14 | -2.465 | 3.206 | 65 | Yes | - |
POLR2H | 5437 | 1 | -1.960 | 2.789 | 41 | - | - |
SRSF3 | 6428 | 73 | -2.992 | 3.538 | 54 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
CHGB | 1114 | POLR2E | 5434 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, MINT, StelzlLow; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
SRSF3 | 6428 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
POLR2D | 5433 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
POLR2E | 5434 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
POLR2D | 5433 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
HCFC1 | 3054 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
POLR2D | 5433 | POLR2H | 5437 | pp | -- | int.I2D: BCI, BioGrid, BIND, HPRD; int.Ravasi: -; int.HPRD: in vitro |
POLR2E | 5434 | POLR2L | 5441 | pp | -- | int.I2D: BCI, BioGrid, BioGrid_Yeast, HPRD, Krogan_Core, MINT_Yeast, YeastMedium, BIND; int.Ravasi: -; int.HPRD: in vitro |
HCFC1 | 3054 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
EIF2S3 | 1968 | LARS | 51520 | pp | -- | int.I2D: YeastLow |
POLR2E | 5434 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
MED28 | 80306 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
POLR2L | 5441 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
YAP1 | 10413 | MED28 | 80306 | pp | -- | int.I2D: MINT; int.Mint: MI:0915(physical association) |
APLP2 | 334 | MED12 | 9968 | pp | -- | int.I2D: MINT; int.Mint: MI:0407(direct interaction) |
POLR2H | 5437 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
EIF2S3 | 1968 | EIF2S2 | 8894 | pp | -- | int.Intact: MI:0407(direct interaction); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Yu_GoldStd |
EIF2S3 | 1968 | PSMD2 | 5708 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
POLR2E | 5434 | MED12 | 9968 | pp | -- | int.I2D: BioGrid |
MED12 | 9968 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
MED12 | 9968 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
POLR2E | 5434 | POLR2H | 5437 | pp | -- | int.I2D: BCI, BioGrid, BIND, HPRD; int.Ravasi: -; int.HPRD: in vitro |
POLR2H | 5437 | POLR2L | 5441 | pp | -- | int.I2D: BCI, BIND, HPRD, BioGrid; int.Ravasi: -; int.HPRD: in vitro |
LUC7L3 | 51747 | MED19 | 219541 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
POLR2D | 5433 | POLR2E | 5434 | pp | -- | int.I2D: BCI, BioGrid, BIND, HPRD; int.Ravasi: -; int.HPRD: in vitro |
PSMD2 | 5708 | LARS | 51520 | pp | -- | int.I2D: BioGrid_Yeast |
EIF2S3 | 1968 | POLR2E | 5434 | pp | -- | int.I2D: YeastLow |
POLR2L | 5441 | MED28 | 80306 | pp | -- | int.I2D: BioGrid |
POLR2D | 5433 | POLR2L | 5441 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BIND, HPRD; int.Ravasi: -; int.HPRD: in vitro |
POLR2E | 5434 | LARS | 51520 | pp | -- | int.I2D: YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0010467 | gene expression | 4.66e-11 | 6.73e-07 | 3.720 | 11 | 45 | 669 |
GO:0005665 | DNA-directed RNA polymerase II, core complex | 3.06e-09 | 4.42e-05 | 7.646 | 4 | 4 | 16 |
GO:0006366 | transcription from RNA polymerase II promoter | 1.61e-08 | 2.32e-04 | 3.935 | 8 | 30 | 419 |
GO:0006370 | 7-methylguanosine mRNA capping | 4.56e-08 | 6.58e-04 | 6.739 | 4 | 5 | 30 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 6.49e-08 | 9.37e-04 | 4.708 | 6 | 22 | 184 |
GO:0001055 | RNA polymerase II activity | 9.10e-08 | 1.31e-03 | 8.231 | 3 | 3 | 8 |
GO:0005654 | nucleoplasm | 1.36e-07 | 1.96e-03 | 2.889 | 10 | 64 | 1082 |
GO:0050434 | positive regulation of viral transcription | 2.23e-07 | 3.22e-03 | 6.187 | 4 | 5 | 44 |
GO:0008380 | RNA splicing | 2.31e-07 | 3.34e-03 | 4.398 | 6 | 22 | 228 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 2.68e-07 | 3.87e-03 | 6.123 | 4 | 4 | 46 |
GO:0001054 | RNA polymerase I activity | 2.68e-07 | 3.86e-03 | 7.772 | 3 | 3 | 11 |
GO:0005736 | DNA-directed RNA polymerase I complex | 3.57e-07 | 5.14e-03 | 7.646 | 3 | 3 | 12 |
GO:0001056 | RNA polymerase III activity | 9.05e-07 | 1.30e-02 | 7.231 | 3 | 3 | 16 |
GO:0005666 | DNA-directed RNA polymerase III complex | 1.10e-06 | 1.58e-02 | 7.144 | 3 | 3 | 17 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 1.24e-06 | 1.79e-02 | 5.580 | 4 | 6 | 67 |
GO:0006289 | nucleotide-excision repair | 1.32e-06 | 1.90e-02 | 5.559 | 4 | 5 | 68 |
GO:0006386 | termination of RNA polymerase III transcription | 1.32e-06 | 1.90e-02 | 7.061 | 3 | 3 | 18 |
GO:0006385 | transcription elongation from RNA polymerase III promoter | 1.32e-06 | 1.90e-02 | 7.061 | 3 | 3 | 18 |
GO:0000398 | mRNA splicing, via spliceosome | 1.36e-06 | 1.96e-02 | 4.611 | 5 | 15 | 164 |
GO:0003899 | DNA-directed RNA polymerase activity | 3.69e-06 | 5.32e-02 | 6.587 | 3 | 3 | 25 |
GO:0006360 | transcription from RNA polymerase I promoter | 6.49e-06 | 9.36e-02 | 6.324 | 3 | 3 | 30 |
GO:0016592 | mediator complex | 1.04e-05 | 1.50e-01 | 6.102 | 3 | 10 | 35 |
GO:0006383 | transcription from RNA polymerase III promoter | 1.45e-05 | 2.09e-01 | 5.946 | 3 | 3 | 39 |
GO:0032481 | positive regulation of type I interferon production | 5.61e-05 | 8.10e-01 | 5.300 | 3 | 6 | 61 |
GO:0006281 | DNA repair | 2.63e-04 | 1.00e+00 | 3.618 | 4 | 14 | 261 |
GO:0016032 | viral process | 3.92e-04 | 1.00e+00 | 2.907 | 5 | 26 | 534 |
GO:0008135 | translation factor activity, nucleic acid binding | 3.99e-04 | 1.00e+00 | 6.061 | 2 | 3 | 24 |
GO:0001104 | RNA polymerase II transcription cofactor activity | 7.59e-04 | 1.00e+00 | 5.602 | 2 | 8 | 33 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0005829 | cytosol | 1.48e-03 | 1.00e+00 | 1.531 | 9 | 86 | 2496 |
GO:0019827 | stem cell maintenance | 1.54e-03 | 1.00e+00 | 5.092 | 2 | 7 | 47 |
GO:0003743 | translation initiation factor activity | 1.67e-03 | 1.00e+00 | 5.031 | 2 | 7 | 49 |
GO:0005515 | protein binding | 2.10e-03 | 1.00e+00 | 0.897 | 14 | 198 | 6024 |
GO:0005634 | nucleus | 2.35e-03 | 1.00e+00 | 1.077 | 12 | 159 | 4559 |
GO:0006429 | leucyl-tRNA aminoacylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0031990 | mRNA export from nucleus in response to heat stress | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 2 |
GO:0019046 | release from viral latency | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 2 |
GO:0002176 | male germ cell proliferation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0004823 | leucine-tRNA ligase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0003677 | DNA binding | 2.74e-03 | 1.00e+00 | 1.981 | 6 | 49 | 1218 |
GO:0003713 | transcription coactivator activity | 2.98e-03 | 1.00e+00 | 3.342 | 3 | 24 | 237 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0046914 | transition metal ion binding | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0090245 | axis elongation involved in somitogenesis | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0014044 | Schwann cell development | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0051151 | negative regulation of smooth muscle cell differentiation | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0070461 | SAGA-type complex | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 2 | 5 |
GO:0001714 | endodermal cell fate specification | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0007176 | regulation of epidermal growth factor-activated receptor activity | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0006356 | regulation of transcription from RNA polymerase I promoter | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0002161 | aminoacyl-tRNA editing activity | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0007617 | mating behavior | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0043254 | regulation of protein complex assembly | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0043995 | histone acetyltransferase activity (H4-K5 specific) | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 5 | 9 |
GO:0046972 | histone acetyltransferase activity (H4-K16 specific) | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 5 | 9 |
GO:0048188 | Set1C/COMPASS complex | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 4 | 9 |
GO:0006450 | regulation of translational fidelity | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0043996 | histone acetyltransferase activity (H4-K8 specific) | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 5 | 9 |
GO:0006413 | translational initiation | 1.14e-02 | 1.00e+00 | 3.613 | 2 | 7 | 131 |
GO:0035413 | positive regulation of catenin import into nucleus | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 10 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 10 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 4 | 11 |
GO:0006878 | cellular copper ion homeostasis | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0005838 | proteasome regulatory particle | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0045948 | positive regulation of translational initiation | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 12 |
GO:0071480 | cellular response to gamma radiation | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 13 |
GO:0030234 | enzyme regulator activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 13 |
GO:0001967 | suckling behavior | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0030518 | intracellular steroid hormone receptor signaling pathway | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 6 | 14 |
GO:0005685 | U1 snRNP | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 14 |
GO:0044212 | transcription regulatory region DNA binding | 1.83e-02 | 1.00e+00 | 3.254 | 2 | 17 | 168 |
GO:0043981 | histone H4-K5 acetylation | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 5 | 15 |
GO:0031369 | translation initiation factor binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 15 |
GO:0042809 | vitamin D receptor binding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 6 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 3 | 15 |
GO:0001824 | blastocyst development | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 15 |
GO:0043982 | histone H4-K8 acetylation | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 5 | 15 |
GO:0006376 | mRNA splice site selection | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 15 |
GO:0016607 | nuclear speck | 1.91e-02 | 1.00e+00 | 3.220 | 2 | 12 | 172 |
GO:0043274 | phospholipase binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 16 |
GO:0001190 | RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 16 |
GO:0022624 | proteasome accessory complex | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 1 | 17 |
GO:0043984 | histone H4-K16 acetylation | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 5 | 19 |
GO:0014003 | oligodendrocyte development | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 5 | 20 |
GO:0043393 | regulation of protein binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 20 |
GO:0000123 | histone acetyltransferase complex | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 6 | 21 |
GO:0045787 | positive regulation of cell cycle | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 22 |
GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 22 |
GO:0030864 | cortical actin cytoskeleton | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 23 |
GO:0006362 | transcription elongation from RNA polymerase I promoter | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 23 |
GO:0006363 | termination of RNA polymerase I transcription | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 1 | 24 |
GO:0006355 | regulation of transcription, DNA-templated | 3.18e-02 | 1.00e+00 | 1.685 | 4 | 43 | 997 |
GO:0035329 | hippo signaling | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 5 | 26 |
GO:0006361 | transcription initiation from RNA polymerase I promoter | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 26 |
GO:0046966 | thyroid hormone receptor binding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 6 | 26 |
GO:0006412 | translation | 3.28e-02 | 1.00e+00 | 2.801 | 2 | 8 | 230 |
GO:0071339 | MLL1 complex | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 6 | 27 |
GO:0003727 | single-stranded RNA binding | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 2 | 28 |
GO:0030901 | midbrain development | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 1 | 29 |
GO:0045087 | innate immune response | 3.61e-02 | 1.00e+00 | 2.012 | 3 | 15 | 596 |
GO:0044822 | poly(A) RNA binding | 3.83e-02 | 1.00e+00 | 1.602 | 4 | 50 | 1056 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 32 |
GO:0000166 | nucleotide binding | 4.07e-02 | 1.00e+00 | 2.629 | 2 | 13 | 259 |
GO:0030178 | negative regulation of Wnt signaling pathway | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 4 | 35 |
GO:0035019 | somatic stem cell maintenance | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 6 | 40 |
GO:0050885 | neuromuscular process controlling balance | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 2 | 40 |
GO:0030521 | androgen receptor signaling pathway | 5.00e-02 | 1.00e+00 | 4.289 | 1 | 5 | 41 |
GO:0016020 | membrane | 5.01e-02 | 1.00e+00 | 1.253 | 5 | 46 | 1681 |
GO:0006418 | tRNA aminoacylation for protein translation | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 3 | 42 |
GO:0031124 | mRNA 3'-end processing | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 2 | 42 |
GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 7 | 43 |
GO:0003712 | transcription cofactor activity | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 8 | 44 |
GO:0006369 | termination of RNA polymerase II transcription | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 2 | 45 |
GO:0030900 | forebrain development | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 1 | 49 |
GO:0006521 | regulation of cellular amino acid metabolic process | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 1 | 50 |
GO:0003682 | chromatin binding | 6.18e-02 | 1.00e+00 | 2.293 | 2 | 19 | 327 |
GO:0009611 | response to wounding | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 5 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 4 | 53 |
GO:0000932 | cytoplasmic mRNA processing body | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 4 | 54 |
GO:0003723 | RNA binding | 6.68e-02 | 1.00e+00 | 2.228 | 2 | 18 | 342 |
GO:0008203 | cholesterol metabolic process | 6.88e-02 | 1.00e+00 | 3.813 | 1 | 2 | 57 |
GO:0000502 | proteasome complex | 7.00e-02 | 1.00e+00 | 3.788 | 1 | 3 | 58 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.21e-02 | 1.00e+00 | 1.607 | 3 | 41 | 789 |
GO:0008013 | beta-catenin binding | 7.23e-02 | 1.00e+00 | 3.739 | 1 | 9 | 60 |
GO:0006406 | mRNA export from nucleus | 7.35e-02 | 1.00e+00 | 3.715 | 1 | 4 | 61 |
GO:0030141 | secretory granule | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 4 | 62 |
GO:0004867 | serine-type endopeptidase inhibitor activity | 7.58e-02 | 1.00e+00 | 3.669 | 1 | 3 | 63 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 7.70e-02 | 1.00e+00 | 3.646 | 1 | 1 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.81e-02 | 1.00e+00 | 3.624 | 1 | 2 | 65 |
GO:0010468 | regulation of gene expression | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 2 | 68 |
GO:0003697 | single-stranded DNA binding | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 5 | 68 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.39e-02 | 1.00e+00 | 3.517 | 1 | 2 | 70 |
GO:0007626 | locomotory behavior | 8.50e-02 | 1.00e+00 | 3.496 | 1 | 2 | 71 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 1 | 72 |
GO:0003729 | mRNA binding | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 4 | 72 |
GO:0001843 | neural tube closure | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 2 | 74 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 2 | 74 |
GO:0008584 | male gonad development | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 3 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 1 | 75 |
GO:0060070 | canonical Wnt signaling pathway | 8.96e-02 | 1.00e+00 | 3.417 | 1 | 4 | 75 |
GO:0005179 | hormone activity | 9.42e-02 | 1.00e+00 | 3.342 | 1 | 1 | 79 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 9.42e-02 | 1.00e+00 | 3.342 | 1 | 2 | 79 |
GO:0009653 | anatomical structure morphogenesis | 9.87e-02 | 1.00e+00 | 3.271 | 1 | 2 | 83 |
GO:0050821 | protein stabilization | 1.04e-01 | 1.00e+00 | 3.187 | 1 | 3 | 88 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 1 | 92 |
GO:0044267 | cellular protein metabolic process | 1.17e-01 | 1.00e+00 | 1.757 | 2 | 20 | 474 |
GO:0042802 | identical protein binding | 1.21e-01 | 1.00e+00 | 1.727 | 2 | 19 | 484 |
GO:0010951 | negative regulation of endopeptidase activity | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 6 | 104 |
GO:0000209 | protein polyubiquitination | 1.35e-01 | 1.00e+00 | 2.788 | 1 | 3 | 116 |
GO:0006325 | chromatin organization | 1.38e-01 | 1.00e+00 | 2.764 | 1 | 12 | 118 |
GO:0008201 | heparin binding | 1.42e-01 | 1.00e+00 | 2.715 | 1 | 1 | 122 |
GO:0007507 | heart development | 1.60e-01 | 1.00e+00 | 2.527 | 1 | 7 | 139 |
GO:0010628 | positive regulation of gene expression | 1.67e-01 | 1.00e+00 | 2.456 | 1 | 7 | 146 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.71e-01 | 1.00e+00 | 2.427 | 1 | 3 | 149 |
GO:0042981 | regulation of apoptotic process | 1.72e-01 | 1.00e+00 | 2.417 | 1 | 4 | 150 |
GO:0006974 | cellular response to DNA damage stimulus | 1.73e-01 | 1.00e+00 | 2.408 | 1 | 7 | 151 |
GO:0008022 | protein C-terminus binding | 1.83e-01 | 1.00e+00 | 2.315 | 1 | 8 | 161 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.93e-01 | 1.00e+00 | 2.228 | 1 | 2 | 171 |
GO:0007049 | cell cycle | 1.96e-01 | 1.00e+00 | 2.203 | 1 | 6 | 174 |
GO:0005667 | transcription factor complex | 1.97e-01 | 1.00e+00 | 2.195 | 1 | 17 | 175 |
GO:0031625 | ubiquitin protein ligase binding | 2.00e-01 | 1.00e+00 | 2.170 | 1 | 5 | 178 |
GO:0003714 | transcription corepressor activity | 2.00e-01 | 1.00e+00 | 2.170 | 1 | 11 | 178 |
GO:0019904 | protein domain specific binding | 2.01e-01 | 1.00e+00 | 2.162 | 1 | 8 | 179 |
GO:0004872 | receptor activity | 2.11e-01 | 1.00e+00 | 2.084 | 1 | 8 | 189 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 2.16e-01 | 1.00e+00 | 1.197 | 2 | 39 | 699 |
GO:0003924 | GTPase activity | 2.19e-01 | 1.00e+00 | 2.024 | 1 | 7 | 197 |
GO:0001701 | in utero embryonic development | 2.23e-01 | 1.00e+00 | 1.995 | 1 | 8 | 201 |
GO:0006184 | GTP catabolic process | 2.36e-01 | 1.00e+00 | 1.905 | 1 | 7 | 214 |
GO:0016071 | mRNA metabolic process | 2.45e-01 | 1.00e+00 | 1.845 | 1 | 8 | 223 |
GO:0008134 | transcription factor binding | 2.63e-01 | 1.00e+00 | 1.727 | 1 | 18 | 242 |
GO:0043025 | neuronal cell body | 2.66e-01 | 1.00e+00 | 1.710 | 1 | 9 | 245 |
GO:0016070 | RNA metabolic process | 2.67e-01 | 1.00e+00 | 1.698 | 1 | 8 | 247 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 2.83e-01 | 1.00e+00 | 1.602 | 1 | 23 | 264 |
GO:0003779 | actin binding | 2.85e-01 | 1.00e+00 | 1.591 | 1 | 10 | 266 |
GO:0030198 | extracellular matrix organization | 3.00e-01 | 1.00e+00 | 1.502 | 1 | 6 | 283 |
GO:0007186 | G-protein coupled receptor signaling pathway | 3.05e-01 | 1.00e+00 | 1.471 | 1 | 1 | 289 |
GO:0005525 | GTP binding | 3.24e-01 | 1.00e+00 | 1.370 | 1 | 12 | 310 |
GO:0008283 | cell proliferation | 3.39e-01 | 1.00e+00 | 1.289 | 1 | 14 | 328 |
GO:0043565 | sequence-specific DNA binding | 3.54e-01 | 1.00e+00 | 1.212 | 1 | 11 | 346 |
GO:0005925 | focal adhesion | 3.71e-01 | 1.00e+00 | 1.130 | 1 | 9 | 366 |
GO:0000278 | mitotic cell cycle | 3.90e-01 | 1.00e+00 | 1.035 | 1 | 15 | 391 |
GO:0043066 | negative regulation of apoptotic process | 4.16e-01 | 1.00e+00 | 0.918 | 1 | 16 | 424 |
GO:0045893 | positive regulation of transcription, DNA-templated | 4.55e-01 | 1.00e+00 | 0.745 | 1 | 24 | 478 |
GO:0006915 | apoptotic process | 5.07e-01 | 1.00e+00 | 0.530 | 1 | 12 | 555 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 5.16e-01 | 1.00e+00 | 0.491 | 1 | 37 | 570 |
GO:0005737 | cytoplasm | 5.25e-01 | 1.00e+00 | 0.089 | 5 | 124 | 3767 |
GO:0070062 | extracellular vesicular exosome | 5.96e-01 | 1.00e+00 | 0.002 | 3 | 57 | 2400 |
GO:0005730 | nucleolus | 6.24e-01 | 1.00e+00 | -0.034 | 2 | 66 | 1641 |
GO:0005576 | extracellular region | 7.04e-01 | 1.00e+00 | -0.233 | 1 | 13 | 942 |
GO:0005739 | mitochondrion | 7.25e-01 | 1.00e+00 | -0.317 | 1 | 23 | 998 |
GO:0008270 | zinc ion binding | 7.25e-01 | 1.00e+00 | -0.315 | 1 | 27 | 997 |
GO:0044281 | small molecule metabolic process | 7.94e-01 | 1.00e+00 | -0.596 | 1 | 20 | 1211 |
GO:0005524 | ATP binding | 8.17e-01 | 1.00e+00 | -0.696 | 1 | 31 | 1298 |
GO:0046872 | metal ion binding | 8.19e-01 | 1.00e+00 | -0.706 | 1 | 29 | 1307 |
GO:0006351 | transcription, DNA-templated | 8.51e-01 | 1.00e+00 | -0.852 | 1 | 57 | 1446 |
GO:0005886 | plasma membrane | 8.59e-01 | 1.00e+00 | -0.688 | 2 | 49 | 2582 |
GO:0016021 | integral component of membrane | 9.30e-01 | 1.00e+00 | -1.307 | 1 | 17 | 1982 |