meta-int-snw-7528

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-11277	wolf-screen-ratio-mammosphere-adherent	0.882	1.09e-07	9.11e-04	1.96e-03	10	9
int-snw-7528	wolf-screen-ratio-mammosphere-adherent	0.943	8.16e-16	2.09e-03	3.54e-02	13	13
reg-snw-4522	wolf-screen-ratio-mammosphere-adherent	0.815	1.50e-06	3.75e-03	6.95e-03	14	12
reg-snw-317781	wolf-screen-ratio-mammosphere-adherent	0.823	1.13e-06	3.23e-03	6.07e-03	9	9
reg-snw-1841	wolf-screen-ratio-mammosphere-adherent	0.802	2.40e-06	4.81e-03	8.67e-03	9	8
reg-snw-1434	wolf-screen-ratio-mammosphere-adherent	0.865	2.23e-07	1.35e-03	2.78e-03	9	7
reg-snw-7407	wolf-screen-ratio-mammosphere-adherent	0.938	9.82e-09	2.39e-04	5.97e-04	8	8
reg-snw-6723	wolf-screen-ratio-mammosphere-adherent	0.840	5.77e-07	2.25e-03	4.41e-03	13	11

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-7528 subnetwork

Genes (37)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
SRM	6723	13	-0.064	0.840	32	-	-
PSMB1	5689	61	0.688	0.901	113	Yes	-
PHB2	11331	43	0.829	0.956	151	Yes	-
POLR2F	5435	62	0.891	0.956	26	Yes	-
CSE1L	1434	41	0.304	0.865	54	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
DDX51	317781	53	0.059	0.823	210	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
CAD	790	91	0.807	0.973	400	-	-
EIF6	3692	67	0.700	0.876	316	Yes	-
CCNA2	890	54	0.550	0.973	246	Yes	-
MCM5	4174	23	0.578	0.830	273	Yes	-
RPS11	6205	62	0.993	1.113	175	Yes	-
EFTUD2	9343	93	0.883	0.956	108	Yes	-
BCL6	604	8	0.496	0.943	92	Yes	-
TUBG1	7283	98	0.974	0.973	91	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
RAN	5901	89	0.632	0.899	258	Yes	-
FBL	2091	42	0.839	0.956	79	Yes	-
PRMT3	10196	49	0.431	0.815	26	-	-
MTHFD1	4522	49	0.194	0.815	26	Yes	-
DTYMK	1841	6	0.397	0.802	76	-	-
RBX1	9978	115	1.185	0.934	148	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
PSMA1	5682	100	0.996	0.878	152	Yes	-
TREX1	11277	51	-0.051	0.882	91	Yes	-
RPSA	3921	120	1.327	1.151	152	Yes	-
RPA1	6117	51	0.425	0.865	74	-	-
PES1	23481	17	0.513	0.876	254	Yes	-
ACO2	50	65	1.000	1.076	191	Yes	-
RUVBL1	8607	95	0.720	0.973	469	Yes	-
PSMD3	5709	100	0.986	1.106	201	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
RUVBL2	10856	95	0.693	0.956	532	Yes	-
YY1	7528	8	0.359	0.943	114	Yes	-

Interactions (137)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPS11	6205	RUVBL2	10856	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid
CAD	790	MCM5	4174	pd	<	reg.ITFP.txt: no annot
CAD	790	MCM5	4174	pp	--	int.I2D: IntAct_Yeast
ACO2	50	RPA1	6117	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMD11	5717	RUVBL1	8607	pp	--	int.I2D: YeastLow
EIF6	3692	MCM5	4174	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMB1	5689	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
CSE1L	1434	RAN	5901	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG; int.HPRD: in vitro
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pp	--	int.I2D: BioGrid
CAD	790	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	TREX1	11277	pd	<	reg.ITFP.txt: no annot
DTYMK	1841	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
ACTB	60	RUVBL1	8607	pp	--	int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
YY1	7528	RUVBL2	10856	pp	--	int.Intact: MI:0914(association), MI:0915(physical association), MI:0407(direct interaction); int.I2D: BioGrid
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
RPA1	6117	RUVBL1	8607	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1	6117	VARS	7407	pp	--	int.I2D: YeastLow
CAD	790	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RAN	5901	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPA1	6117	TREX1	11277	pp	--	int.I2D: BCI; int.HPRD: in vitro
MCM5	4174	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
CCNA2	890	CSE1L	1434	pd	>	reg.ITFP.txt: no annot
RPA1	6117	RUVBL2	10856	pp	--	int.I2D: YeastLow
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMB1	5689	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast; int.Mint: MI:0915(physical association)
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
TREX1	11277	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
SRM	6723	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
RPSA	3921	VARS	7407	pp	--	int.I2D: IntAct_Yeast
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
RUVBL2	10856	PES1	23481	pd	<>	reg.ITFP.txt: no annot
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
DTYMK	1841	PES1	23481	pd	<	reg.ITFP.txt: no annot
CSE1L	1434	RPA1	6117	pd	<	reg.ITFP.txt: no annot
SRM	6723	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd; int.Ravasi: -; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
RPSA	3921	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
MTHFD1	4522	PES1	23481	pp	--	int.I2D: IntAct_Yeast, YeastLow
MCM5	4174	RPA1	6117	pd	<>	reg.ITFP.txt: no annot
MCM5	4174	RPA1	6117	pp	--	int.I2D: BioGrid_Yeast
FBL	2091	PRMT3	10196	pp	--	int.I2D: BioGrid
ACO2	50	EIF6	3692	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1	4522	PRMT3	10196	pd	<	reg.ITFP.txt: no annot
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	CAD	790	pp	--	int.I2D: IntAct_Yeast
PSMA1	5682	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	RUVBL2	10856	pp	--	int.I2D: YeastLow
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
CAD	790	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
DTYMK	1841	MCM5	4174	pd	<	reg.ITFP.txt: no annot
CSE1L	1434	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	FBL	2091	pp	--	int.I2D: MINT
MCM5	4174	RPA2	6118	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: yeast 2-hybrid
PSMB1	5689	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	DDX51	317781	pd	<	reg.ITFP.txt: no annot
SRM	6723	VARS	7407	pd	<	reg.ITFP.txt: no annot
SRM	6723	VARS	7407	pp	--	int.I2D: YeastLow
MTHFD1	4522	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	VARS	7407	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
YY1	7528	RUVBL1	8607	pp	--	int.Intact: MI:0914(association), MI:0915(physical association), MI:0407(direct interaction); int.I2D: BioGrid
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
EIF6	3692	SRM	6723	pp	--	int.I2D: YeastLow
FBL	2091	RUVBL1	8607	pp	--	int.I2D: BioGrid
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
RPS11	6205	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
RAN	5901	VARS	7407	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	RAN	5901	pp	--	int.I2D: IntAct_Yeast
EIF6	3692	PES1	23481	pd	<	reg.ITFP.txt: no annot
EIF6	3692	PES1	23481	pp	--	int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, MIPS, YeastHigh
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1	4522	RPA1	6117	pd	<	reg.ITFP.txt: no annot
VARS	7407	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
ACO2	50	PES1	23481	pp	--	int.I2D: YeastLow
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMB7	5695	TREX1	11277	pd	<	reg.ITFP.txt: no annot
ACTB	60	YY1	7528	pp	--	int.Intact: MI:0914(association)
DTYMK	1841	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
RPSA	3921	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMB1	5689	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
CAD	790	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	RUVBL2	10856	pp	--	int.I2D: YeastLow
FBL	2091	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
FBL	2091	RUVBL2	10856	pp	--	int.I2D: BioGrid
RPA1	6117	RPA2	6118	pp	--	int.Intact: MI:0407(direct interaction), MI:0915(physical association); int.I2D: HPRD, BCI, BioGrid, BIND, IntAct; int.Transfac: -; int.HPRD: in vitro, in vivo
CAD	790	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
VARS	7407	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
PSMB1	5689	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
ACO2	50	RUVBL1	8607	pp	--	int.I2D: YeastLow
PSMB1	5689	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
CAD	790	PES1	23481	pd	<	reg.ITFP.txt: no annot
ACTB	60	CSE1L	1434	pp	--	int.I2D: IntAct_Yeast
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
SRM	6723	DDX51	317781	pd	<	reg.ITFP.txt: no annot
EIF6	3692	PSMB1	5689	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
DTYMK	1841	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
ACTB	60	RPA1	6117	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMB7	5695	RPA1	6117	pd	<	reg.ITFP.txt: no annot
CCNA2	890	RPA1	6117	pp	--	int.I2D: BioGrid
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
EIF6	3692	DDX51	317781	pd	<	reg.ITFP.txt: no annot
RAN	5901	TREX1	11277	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	TREX1	11277	pd	<>	reg.ITFP.txt: no annot
ACTB	60	MCM5	4174	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
POLR2F	5435	VARS	7407	pd	<	reg.ITFP.txt: no annot
ACTB	60	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
RAN	5901	PES1	23481	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	PHB2	11331	pd	>	reg.ITFP.txt: no annot
RUVBL2	10856	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
BCL6	604	YY1	7528	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, IntAct
EIF6	3692	RUVBL1	8607	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct

Related GO terms (455)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	2.42e-13	3.96e-09	2.936	19	83	1095
GO:0000082	G1/S transition of mitotic cell cycle	3.67e-11	5.99e-07	4.726	9	33	150
GO:0000278	mitotic cell cycle	7.65e-10	1.25e-05	3.608	11	52	398
GO:0010467	gene expression	1.18e-09	1.92e-05	3.100	13	58	669
GO:0006521	regulation of cellular amino acid metabolic process	1.31e-09	2.14e-05	5.726	6	21	50
GO:0000502	proteasome complex	3.30e-09	5.38e-05	5.512	6	22	58
GO:0005730	nucleolus	4.15e-09	6.78e-05	2.237	18	70	1684
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.65e-09	1.09e-04	5.348	6	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.65e-09	1.09e-04	5.348	6	22	65
GO:0016020	membrane	7.41e-09	1.21e-04	2.185	18	80	1746
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.05e-08	1.71e-04	5.241	6	24	70
GO:0005829	cytosol	1.19e-08	1.94e-04	1.854	21	125	2562
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.35e-08	2.21e-04	5.180	6	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.47e-08	2.40e-04	5.160	6	24	74
GO:0016032	viral process	1.84e-08	3.00e-04	3.168	11	55	540
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.87e-08	3.05e-04	5.103	6	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.19e-08	3.57e-04	5.066	6	25	79
GO:0016071	mRNA metabolic process	2.94e-08	4.80e-04	3.984	8	34	223
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.25e-08	1.02e-03	4.815	6	23	94
GO:0016070	RNA metabolic process	6.49e-08	1.06e-03	3.837	8	34	247
GO:0005839	proteasome core complex	6.68e-08	1.09e-03	6.615	4	11	18
GO:0004298	threonine-type endopeptidase activity	1.06e-07	1.72e-03	6.463	4	11	20
GO:0034641	cellular nitrogen compound metabolic process	1.23e-07	2.00e-03	4.125	7	25	177
GO:0000209	protein polyubiquitination	2.20e-07	3.59e-03	4.512	6	21	116
GO:0005634	nucleus	3.70e-07	6.04e-03	1.248	26	131	4828
GO:0070062	extracellular vesicular exosome	3.71e-07	6.05e-03	1.736	19	98	2516
GO:0042981	regulation of apoptotic process	1.04e-06	1.70e-02	4.132	6	26	151
GO:0006281	DNA repair	1.82e-06	2.97e-02	3.548	7	22	264
GO:0016363	nuclear matrix	1.93e-06	3.15e-02	4.583	5	11	92
GO:0035267	NuA4 histone acetyltransferase complex	3.84e-06	6.26e-02	6.563	3	4	14
GO:0031011	Ino80 complex	3.84e-06	6.26e-02	6.563	3	3	14
GO:0003678	DNA helicase activity	1.01e-05	1.65e-01	6.122	3	3	19
GO:0006298	mismatch repair	1.19e-05	1.94e-01	6.048	3	6	20
GO:0005515	protein binding	1.26e-05	2.06e-01	0.959	27	172	6127
GO:0006310	DNA recombination	1.55e-05	2.52e-01	4.719	4	4	67
GO:0044281	small molecule metabolic process	1.69e-05	2.76e-01	2.031	12	57	1295
GO:0006271	DNA strand elongation involved in DNA replication	4.61e-05	7.53e-01	5.416	3	9	31
GO:0000730	DNA recombinase assembly	4.98e-05	8.13e-01	7.463	2	3	5
GO:0032508	DNA duplex unwinding	1.16e-04	1.00e+00	4.978	3	4	42
GO:0000812	Swr1 complex	1.39e-04	1.00e+00	6.785	2	3	8
GO:0006283	transcription-coupled nucleotide-excision repair	1.52e-04	1.00e+00	4.846	3	8	46
GO:0006260	DNA replication	1.78e-04	1.00e+00	3.819	4	12	125
GO:0003684	damaged DNA binding	2.07e-04	1.00e+00	4.698	3	11	51
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.46e-04	1.00e+00	4.615	3	5	54
GO:0006915	apoptotic process	2.55e-04	1.00e+00	2.435	7	34	571
GO:0000724	double-strand break repair via homologous recombination	2.88e-04	1.00e+00	4.537	3	6	57
GO:0043968	histone H2A acetylation	3.25e-04	1.00e+00	6.200	2	3	12
GO:0005838	proteasome regulatory particle	3.25e-04	1.00e+00	6.200	2	7	12
GO:0042273	ribosomal large subunit biogenesis	3.84e-04	1.00e+00	6.085	2	4	13
GO:0005662	DNA replication factor A complex	3.84e-04	1.00e+00	6.085	2	3	13
GO:0043066	negative regulation of apoptotic process	3.90e-04	1.00e+00	2.612	6	30	433
GO:0006289	nucleotide-excision repair	5.07e-04	1.00e+00	4.261	3	12	69
GO:0003697	single-stranded DNA binding	5.07e-04	1.00e+00	4.261	3	9	69
GO:0022624	proteasome accessory complex	6.66e-04	1.00e+00	5.698	2	9	17
GO:0006259	DNA metabolic process	8.35e-04	1.00e+00	5.537	2	3	19
GO:0000718	nucleotide-excision repair, DNA damage removal	1.02e-03	1.00e+00	5.393	2	5	21
GO:0006297	nucleotide-excision repair, DNA gap filling	1.12e-03	1.00e+00	5.326	2	5	22
GO:0032201	telomere maintenance via semi-conservative replication	1.12e-03	1.00e+00	5.326	2	7	22
GO:0043044	ATP-dependent chromatin remodeling	1.23e-03	1.00e+00	5.261	2	4	23
GO:0001649	osteoblast differentiation	1.29e-03	1.00e+00	3.800	3	6	95
GO:0006364	rRNA processing	1.33e-03	1.00e+00	3.785	3	5	96
GO:0006611	protein export from nucleus	1.45e-03	1.00e+00	5.141	2	4	25
GO:0000722	telomere maintenance via recombination	1.57e-03	1.00e+00	5.085	2	7	26
GO:0071339	MLL1 complex	1.69e-03	1.00e+00	5.030	2	3	27
GO:0043022	ribosome binding	1.82e-03	1.00e+00	4.978	2	3	28
GO:0043967	histone H4 acetylation	1.82e-03	1.00e+00	4.978	2	3	28
GO:0031492	nucleosomal DNA binding	1.82e-03	1.00e+00	4.978	2	4	28
GO:0030529	ribonucleoprotein complex	2.17e-03	1.00e+00	3.537	3	8	114
GO:0019058	viral life cycle	2.22e-03	1.00e+00	3.524	3	10	115
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	2.27e-03	1.00e+00	8.785	1	1	1
GO:0070335	aspartate binding	2.27e-03	1.00e+00	8.785	1	1	1
GO:0008262	importin-alpha export receptor activity	2.27e-03	1.00e+00	8.785	1	1	1
GO:1990259	histone-glutamine methyltransferase activity	2.27e-03	1.00e+00	8.785	1	1	1
GO:0032558	adenyl deoxyribonucleotide binding	2.27e-03	1.00e+00	8.785	1	1	1
GO:1990258	histone glutamine methylation	2.27e-03	1.00e+00	8.785	1	1	1
GO:0004151	dihydroorotase activity	2.27e-03	1.00e+00	8.785	1	1	1
GO:0046940	nucleoside monophosphate phosphorylation	2.27e-03	1.00e+00	8.785	1	1	1
GO:0000054	ribosomal subunit export from nucleus	2.27e-03	1.00e+00	8.785	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	2.27e-03	1.00e+00	8.785	1	1	1
GO:0043380	regulation of memory T cell differentiation	2.27e-03	1.00e+00	8.785	1	1	1
GO:0016074	snoRNA metabolic process	2.27e-03	1.00e+00	8.785	1	1	1
GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	2.27e-03	1.00e+00	8.785	1	1	1
GO:0034644	cellular response to UV	2.38e-03	1.00e+00	4.785	2	5	32
GO:0044822	poly(A) RNA binding	2.44e-03	1.00e+00	1.711	8	50	1078
GO:0005524	ATP binding	2.68e-03	1.00e+00	1.552	9	46	1354
GO:0006325	chromatin organization	2.69e-03	1.00e+00	3.427	3	4	123
GO:0006413	translational initiation	3.22e-03	1.00e+00	3.337	3	12	131
GO:0031490	chromatin DNA binding	3.51e-03	1.00e+00	4.500	2	2	39
GO:0006284	base-excision repair	3.51e-03	1.00e+00	4.500	2	7	39
GO:0022627	cytosolic small ribosomal subunit	3.51e-03	1.00e+00	4.500	2	3	39
GO:0004832	valine-tRNA ligase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0006403	RNA localization	4.53e-03	1.00e+00	7.785	1	1	2
GO:0051538	3 iron, 4 sulfur cluster binding	4.53e-03	1.00e+00	7.785	1	1	2
GO:0006233	dTDP biosynthetic process	4.53e-03	1.00e+00	7.785	1	1	2
GO:0003994	aconitate hydratase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0006407	rRNA export from nucleus	4.53e-03	1.00e+00	7.785	1	1	2
GO:0006438	valyl-tRNA aminoacylation	4.53e-03	1.00e+00	7.785	1	1	2
GO:0004766	spermidine synthase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.53e-03	1.00e+00	7.785	1	1	2
GO:0050145	nucleoside phosphate kinase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0034696	response to prostaglandin F	4.53e-03	1.00e+00	7.785	1	1	2
GO:0000105	histidine biosynthetic process	4.53e-03	1.00e+00	7.785	1	1	2
GO:0032764	negative regulation of mast cell cytokine production	4.53e-03	1.00e+00	7.785	1	1	2
GO:0008295	spermidine biosynthetic process	4.53e-03	1.00e+00	7.785	1	1	2
GO:0008296	3'-5'-exodeoxyribonuclease activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.53e-03	1.00e+00	7.785	1	1	2
GO:0005055	laminin receptor activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0004798	thymidylate kinase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0070409	carbamoyl phosphate biosynthetic process	4.53e-03	1.00e+00	7.785	1	1	2
GO:0043234	protein complex	4.58e-03	1.00e+00	2.556	4	17	300
GO:0015030	Cajal body	4.66e-03	1.00e+00	4.293	2	2	45
GO:0031100	organ regeneration	5.72e-03	1.00e+00	4.141	2	4	50
GO:0040008	regulation of growth	5.95e-03	1.00e+00	4.113	2	3	51
GO:0000398	mRNA splicing, via spliceosome	6.13e-03	1.00e+00	3.004	3	12	165
GO:0045629	negative regulation of T-helper 2 cell differentiation	6.79e-03	1.00e+00	7.200	1	1	3
GO:0070545	PeBoW complex	6.79e-03	1.00e+00	7.200	1	1	3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.79e-03	1.00e+00	7.200	1	1	3
GO:0006235	dTTP biosynthetic process	6.79e-03	1.00e+00	7.200	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	6.79e-03	1.00e+00	7.200	1	1	3
GO:0048294	negative regulation of isotype switching to IgE isotypes	6.79e-03	1.00e+00	7.200	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	6.79e-03	1.00e+00	7.200	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	6.79e-03	1.00e+00	7.200	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	6.79e-03	1.00e+00	7.200	1	1	3
GO:0030687	preribosome, large subunit precursor	6.79e-03	1.00e+00	7.200	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	6.79e-03	1.00e+00	7.200	1	1	3
GO:0005840	ribosome	7.89e-03	1.00e+00	3.902	2	2	59
GO:0000723	telomere maintenance	7.89e-03	1.00e+00	3.902	2	8	59
GO:0003723	RNA binding	8.25e-03	1.00e+00	2.313	4	19	355
GO:0032481	positive regulation of type I interferon production	8.41e-03	1.00e+00	3.854	2	6	61
GO:0006302	double-strand break repair	8.68e-03	1.00e+00	3.831	2	8	62
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.04e-03	1.00e+00	6.785	1	1	4
GO:0000212	meiotic spindle organization	9.04e-03	1.00e+00	6.785	1	1	4
GO:0030686	90S preribosome	9.04e-03	1.00e+00	6.785	1	1	4
GO:0019788	NEDD8 ligase activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0001652	granular component	9.04e-03	1.00e+00	6.785	1	1	4
GO:0002634	regulation of germinal center formation	9.04e-03	1.00e+00	6.785	1	1	4
GO:0007000	nucleolus organization	9.04e-03	1.00e+00	6.785	1	1	4
GO:0016274	protein-arginine N-methyltransferase activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0042092	type 2 immune response	9.04e-03	1.00e+00	6.785	1	1	4
GO:0031428	box C/D snoRNP complex	9.04e-03	1.00e+00	6.785	1	1	4
GO:0004329	formate-tetrahydrofolate ligase activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0034969	histone arginine methylation	9.04e-03	1.00e+00	6.785	1	1	4
GO:0006543	glutamine catabolic process	9.04e-03	1.00e+00	6.785	1	1	4
GO:0009396	folic acid-containing compound biosynthetic process	9.04e-03	1.00e+00	6.785	1	1	4
GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	9.04e-03	1.00e+00	6.785	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	9.04e-03	1.00e+00	6.785	1	1	4
GO:0008853	exodeoxyribonuclease III activity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0003924	GTPase activity	1.08e-02	1.00e+00	2.705	3	9	203
GO:0051414	response to cortisol	1.13e-02	1.00e+00	6.463	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	1.13e-02	1.00e+00	6.463	1	2	5
GO:0042256	mature ribosome assembly	1.13e-02	1.00e+00	6.463	1	1	5
GO:0001940	male pronucleus	1.13e-02	1.00e+00	6.463	1	1	5
GO:0009086	methionine biosynthetic process	1.13e-02	1.00e+00	6.463	1	1	5
GO:0032407	MutSalpha complex binding	1.13e-02	1.00e+00	6.463	1	1	5
GO:2000001	regulation of DNA damage checkpoint	1.13e-02	1.00e+00	6.463	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	1.13e-02	1.00e+00	6.463	1	1	5
GO:0071169	establishment of protein localization to chromatin	1.13e-02	1.00e+00	6.463	1	1	5
GO:0043248	proteasome assembly	1.13e-02	1.00e+00	6.463	1	1	5
GO:0006102	isocitrate metabolic process	1.13e-02	1.00e+00	6.463	1	1	5
GO:0030891	VCB complex	1.13e-02	1.00e+00	6.463	1	2	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.13e-02	1.00e+00	6.463	1	1	5
GO:0005827	polar microtubule	1.13e-02	1.00e+00	6.463	1	1	5
GO:0005638	lamin filament	1.13e-02	1.00e+00	6.463	1	1	5
GO:0055086	nucleobase-containing small molecule metabolic process	1.19e-02	1.00e+00	3.595	2	5	73
GO:0006184	GTP catabolic process	1.34e-02	1.00e+00	2.589	3	9	220
GO:0060744	mammary gland branching involved in thelarche	1.35e-02	1.00e+00	6.200	1	1	6
GO:0006101	citrate metabolic process	1.35e-02	1.00e+00	6.200	1	1	6
GO:0043023	ribosomal large subunit binding	1.35e-02	1.00e+00	6.200	1	2	6
GO:0031466	Cul5-RING ubiquitin ligase complex	1.35e-02	1.00e+00	6.200	1	1	6
GO:0002903	negative regulation of B cell apoptotic process	1.35e-02	1.00e+00	6.200	1	1	6
GO:0030957	Tat protein binding	1.35e-02	1.00e+00	6.200	1	4	6
GO:0046134	pyrimidine nucleoside biosynthetic process	1.35e-02	1.00e+00	6.200	1	1	6
GO:0032405	MutLalpha complex binding	1.35e-02	1.00e+00	6.200	1	2	6
GO:0008469	histone-arginine N-methyltransferase activity	1.35e-02	1.00e+00	6.200	1	1	6
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	1.35e-02	1.00e+00	6.200	1	1	6
GO:0071013	catalytic step 2 spliceosome	1.38e-02	1.00e+00	3.481	2	7	79
GO:0019083	viral transcription	1.45e-02	1.00e+00	3.445	2	8	81
GO:0005681	spliceosomal complex	1.52e-02	1.00e+00	3.410	2	3	83
GO:0007067	mitotic nuclear division	1.53e-02	1.00e+00	2.518	3	13	231
GO:0008380	RNA splicing	1.54e-02	1.00e+00	2.512	3	13	232
GO:0000028	ribosomal small subunit assembly	1.58e-02	1.00e+00	5.978	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	1.58e-02	1.00e+00	5.978	1	2	7
GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	1.58e-02	1.00e+00	5.978	1	1	7
GO:0001939	female pronucleus	1.58e-02	1.00e+00	5.978	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	1.58e-02	1.00e+00	5.978	1	2	7
GO:0035999	tetrahydrofolate interconversion	1.58e-02	1.00e+00	5.978	1	1	7
GO:0072341	modified amino acid binding	1.58e-02	1.00e+00	5.978	1	1	7
GO:0000930	gamma-tubulin complex	1.58e-02	1.00e+00	5.978	1	1	7
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.58e-02	1.00e+00	5.978	1	1	7
GO:0006415	translational termination	1.66e-02	1.00e+00	3.342	2	8	87
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.80e-02	1.00e+00	5.785	1	2	8
GO:0001055	RNA polymerase II activity	1.80e-02	1.00e+00	5.785	1	3	8
GO:0070688	MLL5-L complex	1.80e-02	1.00e+00	5.785	1	1	8
GO:0045116	protein neddylation	1.80e-02	1.00e+00	5.785	1	2	8
GO:0000800	lateral element	1.80e-02	1.00e+00	5.785	1	1	8
GO:0019773	proteasome core complex, alpha-subunit complex	1.80e-02	1.00e+00	5.785	1	5	8
GO:0006164	purine nucleotide biosynthetic process	1.80e-02	1.00e+00	5.785	1	2	8
GO:0002467	germinal center formation	1.80e-02	1.00e+00	5.785	1	1	8
GO:0016605	PML body	1.84e-02	1.00e+00	3.261	2	5	92
GO:0006414	translational elongation	1.88e-02	1.00e+00	3.246	2	11	93
GO:0005200	structural constituent of cytoskeleton	1.88e-02	1.00e+00	3.246	2	7	93
GO:0014075	response to amine	2.02e-02	1.00e+00	5.615	1	1	9
GO:0042555	MCM complex	2.02e-02	1.00e+00	5.615	1	2	9
GO:0006228	UTP biosynthetic process	2.02e-02	1.00e+00	5.615	1	1	9
GO:0010389	regulation of G2/M transition of mitotic cell cycle	2.02e-02	1.00e+00	5.615	1	1	9
GO:0000400	four-way junction DNA binding	2.02e-02	1.00e+00	5.615	1	1	9
GO:0032319	regulation of Rho GTPase activity	2.02e-02	1.00e+00	5.615	1	2	9
GO:0031000	response to caffeine	2.02e-02	1.00e+00	5.615	1	2	9
GO:0046655	folic acid metabolic process	2.24e-02	1.00e+00	5.463	1	1	10
GO:0006450	regulation of translational fidelity	2.24e-02	1.00e+00	5.463	1	2	10
GO:0010225	response to UV-C	2.24e-02	1.00e+00	5.463	1	1	10
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	2.24e-02	1.00e+00	5.463	1	1	10
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.32e-02	1.00e+00	3.085	2	8	104
GO:0007283	spermatogenesis	2.43e-02	1.00e+00	2.261	3	6	276
GO:0010569	regulation of double-strand break repair via homologous recombination	2.47e-02	1.00e+00	5.326	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	2.47e-02	1.00e+00	5.326	1	3	11
GO:0001054	RNA polymerase I activity	2.47e-02	1.00e+00	5.326	1	3	11
GO:0045120	pronucleus	2.47e-02	1.00e+00	5.326	1	1	11
GO:0051272	positive regulation of cellular component movement	2.47e-02	1.00e+00	5.326	1	1	11
GO:0033762	response to glucagon	2.47e-02	1.00e+00	5.326	1	1	11
GO:0035024	negative regulation of Rho protein signal transduction	2.47e-02	1.00e+00	5.326	1	1	11
GO:0035458	cellular response to interferon-beta	2.47e-02	1.00e+00	5.326	1	2	11
GO:0070935	3'-UTR-mediated mRNA stabilization	2.69e-02	1.00e+00	5.200	1	2	12
GO:0005736	DNA-directed RNA polymerase I complex	2.69e-02	1.00e+00	5.200	1	3	12
GO:0001953	negative regulation of cell-matrix adhesion	2.69e-02	1.00e+00	5.200	1	1	12
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.75e-02	1.00e+00	2.952	2	10	114
GO:0032479	regulation of type I interferon production	2.91e-02	1.00e+00	5.085	1	2	13
GO:0046939	nucleotide phosphorylation	2.91e-02	1.00e+00	5.085	1	1	13
GO:0030234	enzyme regulator activity	2.91e-02	1.00e+00	5.085	1	3	13
GO:0000738	DNA catabolic process, exonucleolytic	2.91e-02	1.00e+00	5.085	1	2	13
GO:0008266	poly(U) RNA binding	2.91e-02	1.00e+00	5.085	1	1	13
GO:0007020	microtubule nucleation	3.13e-02	1.00e+00	4.978	1	1	14
GO:0007095	mitotic G2 DNA damage checkpoint	3.13e-02	1.00e+00	4.978	1	1	14
GO:0006595	polyamine metabolic process	3.13e-02	1.00e+00	4.978	1	1	14
GO:0045445	myoblast differentiation	3.35e-02	1.00e+00	4.878	1	2	15
GO:0048821	erythrocyte development	3.35e-02	1.00e+00	4.878	1	1	15
GO:0035066	positive regulation of histone acetylation	3.35e-02	1.00e+00	4.878	1	1	15
GO:0006261	DNA-dependent DNA replication	3.35e-02	1.00e+00	4.878	1	2	15
GO:0060749	mammary gland alveolus development	3.35e-02	1.00e+00	4.878	1	1	15
GO:0042176	regulation of protein catabolic process	3.57e-02	1.00e+00	4.785	1	3	16
GO:0005665	DNA-directed RNA polymerase II, core complex	3.57e-02	1.00e+00	4.785	1	4	16
GO:0050998	nitric-oxide synthase binding	3.57e-02	1.00e+00	4.785	1	1	16
GO:0051276	chromosome organization	3.57e-02	1.00e+00	4.785	1	4	16
GO:0001673	male germ cell nucleus	3.57e-02	1.00e+00	4.785	1	1	16
GO:0001056	RNA polymerase III activity	3.57e-02	1.00e+00	4.785	1	3	16
GO:0008408	3'-5' exonuclease activity	3.57e-02	1.00e+00	4.785	1	2	16
GO:0000790	nuclear chromatin	3.65e-02	1.00e+00	2.730	2	7	133
GO:0005525	GTP binding	3.78e-02	1.00e+00	2.012	3	11	328
GO:0010243	response to organonitrogen compound	3.79e-02	1.00e+00	4.698	1	2	17
GO:0005666	DNA-directed RNA polymerase III complex	3.79e-02	1.00e+00	4.698	1	3	17
GO:0033365	protein localization to organelle	3.79e-02	1.00e+00	4.698	1	1	17
GO:0075733	intracellular transport of virus	3.79e-02	1.00e+00	4.698	1	2	17
GO:0048593	camera-type eye morphogenesis	3.79e-02	1.00e+00	4.698	1	1	17
GO:0007126	meiotic nuclear division	3.79e-02	1.00e+00	4.698	1	1	17
GO:0000086	G2/M transition of mitotic cell cycle	3.85e-02	1.00e+00	2.687	2	7	137
GO:0008283	cell proliferation	3.87e-02	1.00e+00	1.999	3	12	331
GO:0003682	chromatin binding	3.95e-02	1.00e+00	1.986	3	12	334
GO:0006386	termination of RNA polymerase III transcription	4.00e-02	1.00e+00	4.615	1	3	18
GO:0071392	cellular response to estradiol stimulus	4.00e-02	1.00e+00	4.615	1	1	18
GO:0006541	glutamine metabolic process	4.00e-02	1.00e+00	4.615	1	1	18
GO:0031122	cytoplasmic microtubule organization	4.00e-02	1.00e+00	4.615	1	2	18
GO:0035861	site of double-strand break	4.00e-02	1.00e+00	4.615	1	1	18
GO:0006385	transcription elongation from RNA polymerase III promoter	4.00e-02	1.00e+00	4.615	1	3	18
GO:0015949	nucleobase-containing small molecule interconversion	4.00e-02	1.00e+00	4.615	1	2	18
GO:0005657	replication fork	4.00e-02	1.00e+00	4.615	1	3	18
GO:0003735	structural constituent of ribosome	4.05e-02	1.00e+00	2.645	2	8	141
GO:0016887	ATPase activity	4.21e-02	1.00e+00	2.615	2	7	144
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	4.22e-02	1.00e+00	4.537	1	1	19
GO:0048863	stem cell differentiation	4.22e-02	1.00e+00	4.537	1	1	19
GO:0048873	homeostasis of number of cells within a tissue	4.44e-02	1.00e+00	4.463	1	1	20
GO:0005719	nuclear euchromatin	4.44e-02	1.00e+00	4.463	1	2	20
GO:0001227	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	4.44e-02	1.00e+00	4.463	1	1	20
GO:0006457	protein folding	4.48e-02	1.00e+00	2.566	2	8	149
GO:0043021	ribonucleoprotein complex binding	4.66e-02	1.00e+00	4.393	1	1	21
GO:0071364	cellular response to epidermal growth factor stimulus	4.66e-02	1.00e+00	4.393	1	1	21
GO:0000793	condensed chromosome	4.66e-02	1.00e+00	4.393	1	1	21
GO:0005737	cytoplasm	4.73e-02	1.00e+00	0.635	14	98	3976
GO:0046686	response to cadmium ion	4.87e-02	1.00e+00	4.326	1	3	22
GO:0033574	response to testosterone	4.87e-02	1.00e+00	4.326	1	2	22
GO:0030863	cortical cytoskeleton	4.87e-02	1.00e+00	4.326	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	4.87e-02	1.00e+00	4.326	1	4	22
GO:0006270	DNA replication initiation	4.87e-02	1.00e+00	4.326	1	5	22
GO:0007052	mitotic spindle organization	4.87e-02	1.00e+00	4.326	1	2	22
GO:0006974	cellular response to DNA damage stimulus	4.97e-02	1.00e+00	2.481	2	8	158
GO:0031463	Cul3-RING ubiquitin ligase complex	5.09e-02	1.00e+00	4.261	1	2	23
GO:0043236	laminin binding	5.09e-02	1.00e+00	4.261	1	1	23
GO:0006513	protein monoubiquitination	5.09e-02	1.00e+00	4.261	1	1	23
GO:0000794	condensed nuclear chromosome	5.30e-02	1.00e+00	4.200	1	2	24
GO:0006206	pyrimidine nucleobase metabolic process	5.30e-02	1.00e+00	4.200	1	2	24
GO:0000060	protein import into nucleus, translocation	5.30e-02	1.00e+00	4.200	1	4	24
GO:0031519	PcG protein complex	5.52e-02	1.00e+00	4.141	1	4	25
GO:0008536	Ran GTPase binding	5.52e-02	1.00e+00	4.141	1	2	25
GO:0005844	polysome	5.52e-02	1.00e+00	4.141	1	4	25
GO:0017144	drug metabolic process	5.52e-02	1.00e+00	4.141	1	1	25
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.55e-02	1.00e+00	2.393	2	5	168
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	5.73e-02	1.00e+00	4.085	1	2	26
GO:0006730	one-carbon metabolic process	5.73e-02	1.00e+00	4.085	1	1	26
GO:0004003	ATP-dependent DNA helicase activity	5.95e-02	1.00e+00	4.030	1	3	27
GO:0034080	CENP-A containing nucleosome assembly	5.95e-02	1.00e+00	4.030	1	2	27
GO:0030331	estrogen receptor binding	5.95e-02	1.00e+00	4.030	1	2	27
GO:0019843	rRNA binding	5.95e-02	1.00e+00	4.030	1	3	27
GO:0019894	kinesin binding	6.16e-02	1.00e+00	3.978	1	1	28
GO:0031625	ubiquitin protein ligase binding	6.26e-02	1.00e+00	2.293	2	13	180
GO:0006099	tricarboxylic acid cycle	6.38e-02	1.00e+00	3.927	1	3	29
GO:0019005	SCF ubiquitin ligase complex	6.38e-02	1.00e+00	3.927	1	1	29
GO:0003730	mRNA 3'-UTR binding	6.38e-02	1.00e+00	3.927	1	2	29
GO:0006370	7-methylguanosine mRNA capping	6.59e-02	1.00e+00	3.878	1	4	30
GO:0006360	transcription from RNA polymerase I promoter	6.59e-02	1.00e+00	3.878	1	4	30
GO:0031397	negative regulation of protein ubiquitination	7.01e-02	1.00e+00	3.785	1	1	32
GO:0030890	positive regulation of B cell proliferation	7.64e-02	1.00e+00	3.656	1	1	35
GO:0034332	adherens junction organization	7.85e-02	1.00e+00	3.615	1	1	36
GO:0001895	retina homeostasis	7.85e-02	1.00e+00	3.615	1	1	36
GO:0051084	'de novo' posttranslational protein folding	8.06e-02	1.00e+00	3.576	1	4	37
GO:0018107	peptidyl-threonine phosphorylation	8.06e-02	1.00e+00	3.576	1	1	37
GO:0051539	4 iron, 4 sulfur cluster binding	8.06e-02	1.00e+00	3.576	1	3	37
GO:0070527	platelet aggregation	8.27e-02	1.00e+00	3.537	1	2	38
GO:0050681	androgen receptor binding	8.27e-02	1.00e+00	3.537	1	4	38
GO:0008033	tRNA processing	8.48e-02	1.00e+00	3.500	1	1	39
GO:0006383	transcription from RNA polymerase III promoter	8.48e-02	1.00e+00	3.500	1	3	39
GO:0008026	ATP-dependent helicase activity	8.48e-02	1.00e+00	3.500	1	3	39
GO:0032092	positive regulation of protein binding	8.48e-02	1.00e+00	3.500	1	3	39
GO:0007595	lactation	8.48e-02	1.00e+00	3.500	1	2	39
GO:0000781	chromosome, telomeric region	8.69e-02	1.00e+00	3.463	1	2	40
GO:0043195	terminal bouton	8.90e-02	1.00e+00	3.427	1	1	41
GO:0030521	androgen receptor signaling pathway	8.90e-02	1.00e+00	3.427	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	9.10e-02	1.00e+00	3.393	1	5	42
GO:0071363	cellular response to growth factor stimulus	9.10e-02	1.00e+00	3.393	1	2	42
GO:0014070	response to organic cyclic compound	9.31e-02	1.00e+00	3.359	1	3	43
GO:0048146	positive regulation of fibroblast proliferation	9.52e-02	1.00e+00	3.326	1	2	44
GO:0007286	spermatid development	9.52e-02	1.00e+00	3.326	1	1	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9.52e-02	1.00e+00	3.326	1	2	44
GO:0050434	positive regulation of viral transcription	9.52e-02	1.00e+00	3.326	1	5	44
GO:0005759	mitochondrial matrix	9.76e-02	1.00e+00	1.921	2	12	233
GO:0006412	translation	9.90e-02	1.00e+00	1.908	2	15	235
GO:0042802	identical protein binding	9.92e-02	1.00e+00	1.430	3	18	491
GO:0021762	substantia nigra development	9.93e-02	1.00e+00	3.261	1	1	46
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	1.01e-01	1.00e+00	3.230	1	3	47
GO:0050727	regulation of inflammatory response	1.01e-01	1.00e+00	3.230	1	3	47
GO:0044267	cellular protein metabolic process	1.01e-01	1.00e+00	1.419	3	24	495
GO:0003713	transcription coactivator activity	1.02e-01	1.00e+00	1.884	2	10	239
GO:0019003	GDP binding	1.03e-01	1.00e+00	3.200	1	2	48
GO:0007266	Rho protein signal transduction	1.03e-01	1.00e+00	3.200	1	2	48
GO:0003743	translation initiation factor activity	1.05e-01	1.00e+00	3.170	1	4	49
GO:0035690	cellular response to drug	1.07e-01	1.00e+00	3.141	1	2	50
GO:0006091	generation of precursor metabolites and energy	1.09e-01	1.00e+00	3.113	1	3	51
GO:0000902	cell morphogenesis	1.09e-01	1.00e+00	3.113	1	2	51
GO:0008168	methyltransferase activity	1.11e-01	1.00e+00	3.085	1	1	52
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.16e-01	1.00e+00	3.030	1	2	54
GO:0000226	microtubule cytoskeleton organization	1.18e-01	1.00e+00	3.004	1	3	55
GO:0043627	response to estrogen	1.22e-01	1.00e+00	2.952	1	2	57
GO:0030097	hemopoiesis	1.24e-01	1.00e+00	2.927	1	3	58
GO:0045216	cell-cell junction organization	1.26e-01	1.00e+00	2.902	1	2	59
GO:0030183	B cell differentiation	1.26e-01	1.00e+00	2.902	1	1	59
GO:0005643	nuclear pore	1.26e-01	1.00e+00	2.902	1	4	59
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.28e-01	1.00e+00	1.682	2	6	275
GO:0005758	mitochondrial intermembrane space	1.31e-01	1.00e+00	2.831	1	1	62
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.31e-01	1.00e+00	2.831	1	1	62
GO:0019903	protein phosphatase binding	1.33e-01	1.00e+00	2.808	1	4	63
GO:0042995	cell projection	1.33e-01	1.00e+00	2.808	1	6	63
GO:0019899	enzyme binding	1.38e-01	1.00e+00	1.615	2	11	288
GO:0006368	transcription elongation from RNA polymerase II promoter	1.41e-01	1.00e+00	2.719	1	6	67
GO:0006338	chromatin remodeling	1.43e-01	1.00e+00	2.698	1	4	68
GO:0034329	cell junction assembly	1.49e-01	1.00e+00	2.635	1	1	71
GO:0006200	ATP catabolic process	1.50e-01	1.00e+00	1.542	2	14	303
GO:0032355	response to estradiol	1.53e-01	1.00e+00	2.595	1	5	73
GO:0000785	chromatin	1.53e-01	1.00e+00	2.595	1	5	73
GO:0006767	water-soluble vitamin metabolic process	1.57e-01	1.00e+00	2.556	1	3	75
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1.57e-01	1.00e+00	2.556	1	1	75
GO:0007265	Ras protein signal transduction	1.57e-01	1.00e+00	2.556	1	3	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	1.59e-01	1.00e+00	2.537	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	1.61e-01	1.00e+00	2.518	1	5	77
GO:0045087	innate immune response	1.63e-01	1.00e+00	1.103	3	20	616
GO:0006766	vitamin metabolic process	1.63e-01	1.00e+00	2.500	1	3	78
GO:0019901	protein kinase binding	1.64e-01	1.00e+00	1.463	2	21	320
GO:0050776	regulation of immune response	1.65e-01	1.00e+00	2.481	1	1	79
GO:0006334	nucleosome assembly	1.65e-01	1.00e+00	2.481	1	4	79
GO:0007565	female pregnancy	1.66e-01	1.00e+00	2.463	1	2	80
GO:0001889	liver development	1.70e-01	1.00e+00	2.427	1	3	82
GO:0009952	anterior/posterior pattern specification	1.74e-01	1.00e+00	2.393	1	2	84
GO:0047485	protein N-terminus binding	1.78e-01	1.00e+00	2.359	1	4	86
GO:0005813	centrosome	1.79e-01	1.00e+00	1.380	2	12	339
GO:0003690	double-stranded DNA binding	1.87e-01	1.00e+00	2.277	1	4	91
GO:0042470	melanosome	1.89e-01	1.00e+00	2.261	1	10	92
GO:0006928	cellular component movement	1.89e-01	1.00e+00	2.261	1	7	92
GO:0051082	unfolded protein binding	1.94e-01	1.00e+00	2.215	1	6	95
GO:0071456	cellular response to hypoxia	2.00e-01	1.00e+00	2.170	1	4	98
GO:0005925	focal adhesion	2.04e-01	1.00e+00	1.254	2	18	370
GO:0051726	regulation of cell cycle	2.07e-01	1.00e+00	2.113	1	3	102
GO:0005739	mitochondrion	2.11e-01	1.00e+00	0.754	4	24	1046
GO:0014069	postsynaptic density	2.14e-01	1.00e+00	2.057	1	1	106
GO:0005815	microtubule organizing center	2.22e-01	1.00e+00	2.004	1	4	110
GO:0015630	microtubule cytoskeleton	2.25e-01	1.00e+00	1.978	1	5	112
GO:0030308	negative regulation of cell growth	2.27e-01	1.00e+00	1.965	1	6	113
GO:0005635	nuclear envelope	2.32e-01	1.00e+00	1.927	1	6	116
GO:0072562	blood microparticle	2.32e-01	1.00e+00	1.927	1	4	116
GO:0044237	cellular metabolic process	2.36e-01	1.00e+00	1.902	1	3	118
GO:0007219	Notch signaling pathway	2.48e-01	1.00e+00	1.819	1	4	125
GO:0045892	negative regulation of transcription, DNA-templated	2.50e-01	1.00e+00	1.057	2	14	424
GO:0005506	iron ion binding	2.51e-01	1.00e+00	1.796	1	3	127
GO:0006511	ubiquitin-dependent protein catabolic process	2.51e-01	1.00e+00	1.796	1	5	127
GO:0030036	actin cytoskeleton organization	2.55e-01	1.00e+00	1.774	1	5	129
GO:0007507	heart development	2.75e-01	1.00e+00	1.645	1	5	141
GO:0061024	membrane organization	2.83e-01	1.00e+00	1.595	1	5	146
GO:0006351	transcription, DNA-templated	2.88e-01	1.00e+00	0.477	5	25	1585
GO:0046777	protein autophosphorylation	3.03e-01	1.00e+00	1.481	1	3	158
GO:0045893	positive regulation of transcription, DNA-templated	3.03e-01	1.00e+00	0.857	2	17	487
GO:0006397	mRNA processing	3.20e-01	1.00e+00	1.384	1	3	169
GO:0044212	transcription regulatory region DNA binding	3.23e-01	1.00e+00	1.367	1	6	171
GO:0030424	axon	3.25e-01	1.00e+00	1.359	1	3	172
GO:0016607	nuclear speck	3.29e-01	1.00e+00	1.334	1	4	175
GO:0007049	cell cycle	3.32e-01	1.00e+00	1.317	1	3	177
GO:0004672	protein kinase activity	3.34e-01	1.00e+00	1.309	1	2	178
GO:0005667	transcription factor complex	3.34e-01	1.00e+00	1.309	1	6	178
GO:0003714	transcription corepressor activity	3.35e-01	1.00e+00	1.301	1	7	179
GO:0019904	protein domain specific binding	3.38e-01	1.00e+00	1.285	1	6	181
GO:0015629	actin cytoskeleton	3.41e-01	1.00e+00	1.269	1	5	183
GO:0006367	transcription initiation from RNA polymerase II promoter	3.43e-01	1.00e+00	1.261	1	8	184
GO:0032403	protein complex binding	3.44e-01	1.00e+00	1.254	1	7	185
GO:0001701	in utero embryonic development	3.81e-01	1.00e+00	1.071	1	6	210
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.88e-01	1.00e+00	0.583	2	12	589
GO:0005622	intracellular	4.03e-01	1.00e+00	0.965	1	5	226
GO:0042803	protein homodimerization activity	4.11e-01	1.00e+00	0.516	2	11	617
GO:0046872	metal ion binding	4.28e-01	1.00e+00	0.268	4	24	1465
GO:0008270	zinc ion binding	4.39e-01	1.00e+00	0.311	3	12	1067
GO:0043025	neuronal cell body	4.41e-01	1.00e+00	0.796	1	4	254
GO:0004842	ubiquitin-protein transferase activity	4.43e-01	1.00e+00	0.785	1	4	256
GO:0000166	nucleotide binding	4.63e-01	1.00e+00	0.698	1	6	272
GO:0043065	positive regulation of apoptotic process	4.66e-01	1.00e+00	0.687	1	8	274
GO:0006954	inflammatory response	4.84e-01	1.00e+00	0.610	1	6	289
GO:0007264	small GTPase mediated signal transduction	4.85e-01	1.00e+00	0.605	1	3	290
GO:0016567	protein ubiquitination	4.96e-01	1.00e+00	0.561	1	5	299
GO:0005743	mitochondrial inner membrane	4.97e-01	1.00e+00	0.556	1	5	300
GO:0005856	cytoskeleton	5.10e-01	1.00e+00	0.504	1	8	311
GO:0003700	sequence-specific DNA binding transcription factor activity	5.11e-01	1.00e+00	0.238	2	11	748
GO:0030154	cell differentiation	5.25e-01	1.00e+00	0.441	1	5	325
GO:0007411	axon guidance	5.27e-01	1.00e+00	0.432	1	9	327
GO:0043231	intracellular membrane-bounded organelle	5.33e-01	1.00e+00	0.410	1	8	332
GO:0043565	sequence-specific DNA binding	5.67e-01	1.00e+00	0.273	1	4	365
GO:0008285	negative regulation of cell proliferation	5.69e-01	1.00e+00	0.265	1	11	367
GO:0007155	cell adhesion	5.86e-01	1.00e+00	0.200	1	8	384
GO:0008284	positive regulation of cell proliferation	5.94e-01	1.00e+00	0.170	1	8	392
GO:0003677	DNA binding	6.01e-01	1.00e+00	-0.030	3	26	1351
GO:0006366	transcription from RNA polymerase II promoter	6.24e-01	1.00e+00	0.054	1	12	425
GO:0007596	blood coagulation	6.56e-01	1.00e+00	-0.073	1	14	464
GO:0055114	oxidation-reduction process	6.70e-01	1.00e+00	-0.125	1	11	481
GO:0005789	endoplasmic reticulum membrane	7.71e-01	1.00e+00	-0.528	1	10	636
GO:0005794	Golgi apparatus	7.78e-01	1.00e+00	-0.559	1	14	650
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	8.49e-01	1.00e+00	-0.879	1	19	811
GO:0007165	signal transduction	8.92e-01	1.00e+00	-1.107	1	17	950
GO:0005615	extracellular space	9.06e-01	1.00e+00	-1.195	1	17	1010
GO:0006355	regulation of transcription, DNA-templated	9.25e-01	1.00e+00	-1.324	1	17	1104
GO:0005886	plasma membrane	9.99e-01	1.00e+00	-2.684	1	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-7528

Interacting subnets

Genes (37)

Interactions (137)

Related GO terms (455)