reg-snw-1841

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.802	2.40e-06	4.81e-03	8.67e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-1841 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PES1	23481	5	0.513	0.876	91	TF	Yes	-
[ DTYMK ]	1841	1	0.397	0.802	76	-	-	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
MCM5	4174	5	0.578	0.830	152	TF	Yes	-
PSMD3	5709	9	0.986	0.938	55	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
VARS	7407	7	0.549	0.938	124	TF	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-

Interactions (16)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
VARS	7407	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
DTYMK	1841	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
DTYMK	1841	PES1	23481	pd	<	reg.ITFP.txt: no annot
DTYMK	1841	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
RUVBL2	10856	PES1	23481	pd	<>	reg.ITFP.txt: no annot
DTYMK	1841	MCM5	4174	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
DTYMK	1841	VARS	7407	pd	<	reg.ITFP.txt: no annot

Related GO terms (147)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003678	DNA helicase activity	4.39e-07	4.28e-03	7.499	3	3	18
GO:0032508	DNA duplex unwinding	4.49e-06	4.39e-02	6.421	3	5	38
GO:0000812	Swr1 complex	1.58e-05	1.54e-01	8.276	2	2	7
GO:0031011	Ino80 complex	2.11e-05	2.06e-01	8.083	2	2	8
GO:0043968	histone H2A acetylation	3.39e-05	3.31e-01	7.762	2	2	10
GO:0005654	nucleoplasm	3.40e-05	3.32e-01	2.894	6	55	876
GO:0035267	NuA4 histone acetyltransferase complex	4.96e-05	4.84e-01	7.499	2	3	12
GO:0071339	MLL1 complex	1.15e-04	1.00e+00	6.914	2	2	18
GO:0043967	histone H4 acetylation	1.73e-04	1.00e+00	6.624	2	2	22
GO:0016020	membrane	2.12e-04	1.00e+00	2.431	6	38	1207
GO:0005730	nucleolus	2.22e-04	1.00e+00	2.419	6	41	1217
GO:0040008	regulation of growth	4.95e-04	1.00e+00	5.874	2	2	37
GO:0005524	ATP binding	5.80e-04	1.00e+00	2.605	5	23	892
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	8.68e-04	1.00e+00	5.469	2	3	49
GO:0006310	DNA recombination	9.04e-04	1.00e+00	5.440	2	6	50
GO:0004832	valine-tRNA ligase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006233	dTDP biosynthetic process	9.22e-04	1.00e+00	10.083	1	1	1
GO:0046940	nucleoside monophosphate phosphorylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006438	valyl-tRNA aminoacylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004798	thymidylate kinase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0050145	nucleoside phosphate kinase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006325	chromatin organization	1.77e-03	1.00e+00	4.954	2	3	70
GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.84e-03	1.00e+00	9.083	1	1	2
GO:0016363	nuclear matrix	1.92e-03	1.00e+00	4.894	2	7	73
GO:0000278	mitotic cell cycle	2.39e-03	1.00e+00	3.374	3	35	314
GO:0030529	ribonucleoprotein complex	2.41e-03	1.00e+00	4.726	2	4	82
GO:0071733	transcriptional activation by promoter-enhancer looping	2.76e-03	1.00e+00	8.499	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.76e-03	1.00e+00	8.499	1	1	3
GO:0070545	PeBoW complex	2.76e-03	1.00e+00	8.499	1	1	3
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006235	dTTP biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.76e-03	1.00e+00	8.499	1	1	3
GO:0030687	preribosome, large subunit precursor	2.76e-03	1.00e+00	8.499	1	1	3
GO:0016887	ATPase activity	3.57e-03	1.00e+00	4.440	2	6	100
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0071169	establishment of protein localization to chromatin	3.68e-03	1.00e+00	8.083	1	1	4
GO:0007000	nucleolus organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0042555	MCM complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0000082	G1/S transition of mitotic cell cycle	5.52e-03	1.00e+00	4.118	2	24	125
GO:0046939	nucleotide phosphorylation	6.44e-03	1.00e+00	7.276	1	1	7
GO:0006450	regulation of translational fidelity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0005838	proteasome regulatory particle	9.18e-03	1.00e+00	6.762	1	4	10
GO:0042273	ribosomal large subunit biogenesis	1.01e-02	1.00e+00	6.624	1	3	11
GO:0033365	protein localization to organelle	1.01e-02	1.00e+00	6.624	1	1	11
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0030234	enzyme regulator activity	1.01e-02	1.00e+00	6.624	1	2	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0010467	gene expression	1.07e-02	1.00e+00	2.605	3	31	535
GO:0015949	nucleobase-containing small molecule interconversion	1.10e-02	1.00e+00	6.499	1	2	12
GO:0045445	myoblast differentiation	1.19e-02	1.00e+00	6.383	1	2	13
GO:0071392	cellular response to estradiol stimulus	1.19e-02	1.00e+00	6.383	1	1	13
GO:0035066	positive regulation of histone acetylation	1.19e-02	1.00e+00	6.383	1	1	13
GO:0042176	regulation of protein catabolic process	1.28e-02	1.00e+00	6.276	1	2	14
GO:0022624	proteasome accessory complex	1.28e-02	1.00e+00	6.276	1	7	14
GO:0005829	cytosol	1.34e-02	1.00e+00	1.602	5	58	1787
GO:0006281	DNA repair	1.41e-02	1.00e+00	3.418	2	19	203
GO:0005719	nuclear euchromatin	1.47e-02	1.00e+00	6.083	1	1	16
GO:0000793	condensed chromosome	1.47e-02	1.00e+00	6.083	1	1	16
GO:0043021	ribonucleoprotein complex binding	1.56e-02	1.00e+00	5.996	1	1	17
GO:0006270	DNA replication initiation	1.56e-02	1.00e+00	5.996	1	4	17
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0046686	response to cadmium ion	1.83e-02	1.00e+00	5.762	1	1	20
GO:0008283	cell proliferation	1.92e-02	1.00e+00	3.183	2	6	239
GO:0004003	ATP-dependent DNA helicase activity	2.28e-02	1.00e+00	5.440	1	2	25
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0034644	cellular response to UV	2.55e-02	1.00e+00	5.276	1	2	28
GO:0071363	cellular response to growth factor stimulus	2.55e-02	1.00e+00	5.276	1	1	28
GO:0006418	tRNA aminoacylation for protein translation	2.64e-02	1.00e+00	5.225	1	1	29
GO:0006271	DNA strand elongation involved in DNA replication	2.64e-02	1.00e+00	5.225	1	8	29
GO:0031490	chromatin DNA binding	2.82e-02	1.00e+00	5.129	1	1	31
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.63e-02	1.00e+00	4.762	1	2	40
GO:0006521	regulation of cellular amino acid metabolic process	3.72e-02	1.00e+00	4.726	1	16	41
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	9	41
GO:0042802	identical protein binding	3.99e-02	1.00e+00	2.616	2	7	354
GO:0000502	proteasome complex	4.25e-02	1.00e+00	4.529	1	17	47
GO:0005758	mitochondrial intermembrane space	4.34e-02	1.00e+00	4.499	1	1	48
GO:0043627	response to estrogen	4.43e-02	1.00e+00	4.469	1	1	49
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	4.61e-02	1.00e+00	4.411	1	5	51
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.69e-02	1.00e+00	4.383	1	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.78e-02	1.00e+00	4.356	1	17	53
GO:0070062	extracellular vesicular exosome	4.92e-02	1.00e+00	1.403	4	43	1641
GO:0006338	chromatin remodeling	4.96e-02	1.00e+00	4.302	1	2	55
GO:0005681	spliceosomal complex	4.96e-02	1.00e+00	4.302	1	2	55
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.05e-02	1.00e+00	4.276	1	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.13e-02	1.00e+00	4.251	1	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.40e-02	1.00e+00	4.177	1	17	60
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	5	61
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.49e-02	1.00e+00	4.153	1	16	61
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.84e-02	1.00e+00	4.061	1	17	65
GO:0006364	rRNA processing	6.01e-02	1.00e+00	4.017	1	4	67
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0051082	unfolded protein binding	6.27e-02	1.00e+00	3.954	1	4	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.27e-02	1.00e+00	3.954	1	16	70
GO:0051726	regulation of cell cycle	6.53e-02	1.00e+00	3.894	1	2	73
GO:0005737	cytoplasm	6.58e-02	1.00e+00	1.043	5	50	2633
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	2	74
GO:0005815	microtubule organizing center	6.88e-02	1.00e+00	3.817	1	1	77
GO:0000209	protein polyubiquitination	8.17e-02	1.00e+00	3.560	1	16	92
GO:0006260	DNA replication	8.34e-02	1.00e+00	3.529	1	11	94
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	5	97
GO:0006457	protein folding	8.60e-02	1.00e+00	3.484	1	4	97
GO:0034641	cellular nitrogen compound metabolic process	9.28e-02	1.00e+00	3.369	1	18	105
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	18	112
GO:0007049	cell cycle	1.01e-01	1.00e+00	3.238	1	3	115
GO:0003924	GTPase activity	1.05e-01	1.00e+00	3.189	1	3	119
GO:0000398	mRNA splicing, via spliceosome	1.12e-01	1.00e+00	3.083	1	8	128
GO:0006184	GTP catabolic process	1.14e-01	1.00e+00	3.061	1	3	130
GO:0005759	mitochondrial matrix	1.21e-01	1.00e+00	2.965	1	5	139
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0005622	intracellular	1.26e-01	1.00e+00	2.904	1	1	145
GO:0005515	protein binding	1.26e-01	1.00e+00	0.659	6	76	4124
GO:0008380	RNA splicing	1.42e-01	1.00e+00	2.717	1	7	165
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	8	165
GO:0005634	nucleus	1.43e-01	1.00e+00	0.741	5	67	3246
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0016071	mRNA metabolic process	1.46e-01	1.00e+00	2.674	1	21	170
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	6	176
GO:0016070	RNA metabolic process	1.61e-01	1.00e+00	2.529	1	21	188
GO:0044822	poly(A) RNA binding	1.64e-01	1.00e+00	1.441	2	25	799
GO:0005525	GTP binding	1.68e-01	1.00e+00	2.461	1	5	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0043234	protein complex	1.78e-01	1.00e+00	2.369	1	8	210
GO:0044281	small molecule metabolic process	1.79e-01	1.00e+00	1.362	2	32	844
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	8	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	7	218
GO:0006200	ATP catabolic process	1.85e-01	1.00e+00	2.309	1	8	219
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	11	247
GO:0006351	transcription, DNA-templated	2.61e-01	1.00e+00	1.012	2	9	1076
GO:0043066	negative regulation of apoptotic process	2.61e-01	1.00e+00	1.753	1	20	322
GO:0006915	apoptotic process	3.21e-01	1.00e+00	1.400	1	21	411
GO:0005794	Golgi apparatus	3.24e-01	1.00e+00	1.387	1	5	415
GO:0016032	viral process	3.32e-01	1.00e+00	1.342	1	32	428
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.59e-01	1.00e+00	0.753	1	8	644
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	11	659
GO:0003677	DNA binding	6.01e-01	1.00e+00	0.196	1	18	947

Wolf-ratios-Mammosphere-Adherent

reg-snw-1841

Statistics

Genes (9)

Interactions (16)

Related GO terms (147)