reg-snw-7407

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.938	9.82e-09	2.39e-04	5.97e-04

wolf-screen-ratio-mammosphere-adherent-reg-snw-7407 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMB2	5690	23	0.877	0.956	52	-	Yes	-
[ VARS ]	7407	7	0.549	0.938	124	TF	Yes	-
RUVBL2	10856	20	0.693	0.956	187	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
POLR2F	5435	14	0.891	0.956	5	-	Yes	-
PSMD3	5709	9	0.986	0.938	55	TF	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-

Interactions (14)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	VARS	7407	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
VARS	7407	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot

Related GO terms (139)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.23e-05	1.20e-01	3.064	6	55	876
GO:0000812	Swr1 complex	1.23e-05	1.20e-01	8.446	2	2	7
GO:0031011	Ino80 complex	1.64e-05	1.60e-01	8.253	2	2	8
GO:0010467	gene expression	2.36e-05	2.31e-01	3.512	5	31	535
GO:0043968	histone H2A acetylation	2.63e-05	2.57e-01	7.931	2	2	10
GO:0035267	NuA4 histone acetyltransferase complex	3.86e-05	3.77e-01	7.668	2	3	12
GO:0005730	nucleolus	8.29e-05	8.10e-01	2.589	6	41	1217
GO:0003678	DNA helicase activity	8.93e-05	8.72e-01	7.083	2	3	18
GO:0071339	MLL1 complex	8.93e-05	8.72e-01	7.083	2	2	18
GO:0043967	histone H4 acetylation	1.35e-04	1.00e+00	6.794	2	2	22
GO:0040008	regulation of growth	3.86e-04	1.00e+00	6.044	2	2	37
GO:0032508	DNA duplex unwinding	4.07e-04	1.00e+00	6.005	2	5	38
GO:0006281	DNA repair	4.59e-04	1.00e+00	4.173	3	19	203
GO:0006521	regulation of cellular amino acid metabolic process	4.74e-04	1.00e+00	5.896	2	16	41
GO:0000502	proteasome complex	6.23e-04	1.00e+00	5.699	2	17	47
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.78e-04	1.00e+00	5.639	2	3	49
GO:0006310	DNA recombination	7.05e-04	1.00e+00	5.610	2	6	50
GO:0005829	cytosol	7.44e-04	1.00e+00	2.035	6	58	1787
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.63e-04	1.00e+00	5.553	2	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	7.93e-04	1.00e+00	5.525	2	17	53
GO:0004832	valine-tRNA ligase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0006438	valyl-tRNA aminoacylation	8.19e-04	1.00e+00	10.253	1	1	1
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.85e-04	1.00e+00	5.446	2	17	56
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	9.16e-04	1.00e+00	5.421	2	16	57
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.02e-03	1.00e+00	5.347	2	17	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.05e-03	1.00e+00	5.323	2	16	61
GO:0016020	membrane	1.16e-03	1.00e+00	2.338	5	38	1207
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.19e-03	1.00e+00	5.231	2	17	65
GO:0006325	chromatin organization	1.38e-03	1.00e+00	5.124	2	3	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.38e-03	1.00e+00	5.124	2	16	70
GO:0016363	nuclear matrix	1.50e-03	1.00e+00	5.064	2	7	73
GO:0000278	mitotic cell cycle	1.64e-03	1.00e+00	3.544	3	35	314
GO:0030529	ribonucleoprotein complex	1.89e-03	1.00e+00	4.896	2	4	82
GO:0000209	protein polyubiquitination	2.37e-03	1.00e+00	4.730	2	16	92
GO:0071733	transcriptional activation by promoter-enhancer looping	2.46e-03	1.00e+00	8.668	1	1	3
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	2.46e-03	1.00e+00	8.668	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	2.46e-03	1.00e+00	8.668	1	1	3
GO:0016887	ATPase activity	2.79e-03	1.00e+00	4.610	2	6	100
GO:0034641	cellular nitrogen compound metabolic process	3.07e-03	1.00e+00	4.539	2	18	105
GO:0000212	meiotic spindle organization	3.27e-03	1.00e+00	8.253	1	1	4
GO:0071169	establishment of protein localization to chromatin	3.27e-03	1.00e+00	8.253	1	1	4
GO:0042981	regulation of apoptotic process	3.49e-03	1.00e+00	4.446	2	18	112
GO:0016032	viral process	3.97e-03	1.00e+00	3.097	3	32	428
GO:0005827	polar microtubule	4.09e-03	1.00e+00	7.931	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000930	gamma-tubulin complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000082	G1/S transition of mitotic cell cycle	4.33e-03	1.00e+00	4.288	2	24	125
GO:0000398	mRNA splicing, via spliceosome	4.53e-03	1.00e+00	4.253	2	8	128
GO:0070062	extracellular vesicular exosome	4.77e-03	1.00e+00	1.895	5	43	1641
GO:0001055	RNA polymerase II activity	4.91e-03	1.00e+00	7.668	1	2	6
GO:0006450	regulation of translational fidelity	6.54e-03	1.00e+00	7.253	1	1	8
GO:0031122	cytoplasmic microtubule organization	6.54e-03	1.00e+00	7.253	1	2	8
GO:0008266	poly(U) RNA binding	7.35e-03	1.00e+00	7.083	1	1	9
GO:0008380	RNA splicing	7.43e-03	1.00e+00	3.887	2	7	165
GO:0016071	mRNA metabolic process	7.87e-03	1.00e+00	3.844	2	21	170
GO:0005736	DNA-directed RNA polymerase I complex	8.17e-03	1.00e+00	6.931	1	2	10
GO:0005838	proteasome regulatory particle	8.17e-03	1.00e+00	6.931	1	4	10
GO:0001054	RNA polymerase I activity	8.17e-03	1.00e+00	6.931	1	2	10
GO:0007020	microtubule nucleation	8.98e-03	1.00e+00	6.794	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	8.98e-03	1.00e+00	6.794	1	2	11
GO:0030234	enzyme regulator activity	8.98e-03	1.00e+00	6.794	1	2	11
GO:0045120	pronucleus	8.98e-03	1.00e+00	6.794	1	1	11
GO:0016070	RNA metabolic process	9.56e-03	1.00e+00	3.699	2	21	188
GO:0071392	cellular response to estradiol stimulus	1.06e-02	1.00e+00	6.553	1	1	13
GO:0005666	DNA-directed RNA polymerase III complex	1.06e-02	1.00e+00	6.553	1	2	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.06e-02	1.00e+00	6.553	1	2	13
GO:0001056	RNA polymerase III activity	1.06e-02	1.00e+00	6.553	1	2	13
GO:0035066	positive regulation of histone acetylation	1.06e-02	1.00e+00	6.553	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.14e-02	1.00e+00	6.446	1	2	14
GO:0010243	response to organonitrogen compound	1.14e-02	1.00e+00	6.446	1	1	14
GO:0042176	regulation of protein catabolic process	1.14e-02	1.00e+00	6.446	1	2	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.14e-02	1.00e+00	6.446	1	2	14
GO:0022624	proteasome accessory complex	1.14e-02	1.00e+00	6.446	1	7	14
GO:0005719	nuclear euchromatin	1.30e-02	1.00e+00	6.253	1	1	16
GO:0005839	proteasome core complex	1.30e-02	1.00e+00	6.253	1	9	16
GO:0004298	threonine-type endopeptidase activity	1.38e-02	1.00e+00	6.166	1	9	17
GO:0000794	condensed nuclear chromosome	1.47e-02	1.00e+00	6.083	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.63e-02	1.00e+00	5.931	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.63e-02	1.00e+00	5.931	1	2	20
GO:0005634	nucleus	1.93e-02	1.00e+00	1.174	6	67	3246
GO:0006370	7-methylguanosine mRNA capping	1.95e-02	1.00e+00	5.668	1	2	24
GO:0004003	ATP-dependent DNA helicase activity	2.03e-02	1.00e+00	5.610	1	2	25
GO:0003730	mRNA 3'-UTR binding	2.03e-02	1.00e+00	5.610	1	2	25
GO:0031492	nucleosomal DNA binding	2.03e-02	1.00e+00	5.610	1	2	25
GO:0006360	transcription from RNA polymerase I promoter	2.19e-02	1.00e+00	5.499	1	2	27
GO:0034644	cellular response to UV	2.27e-02	1.00e+00	5.446	1	2	28
GO:0006418	tRNA aminoacylation for protein translation	2.35e-02	1.00e+00	5.395	1	1	29
GO:0006383	transcription from RNA polymerase III promoter	2.35e-02	1.00e+00	5.395	1	2	29
GO:0031490	chromatin DNA binding	2.51e-02	1.00e+00	5.299	1	1	31
GO:0043066	negative regulation of apoptotic process	2.66e-02	1.00e+00	2.922	2	20	322
GO:0014070	response to organic cyclic compound	2.75e-02	1.00e+00	5.166	1	1	34
GO:0050434	positive regulation of viral transcription	2.83e-02	1.00e+00	5.124	1	2	35
GO:0000226	microtubule cytoskeleton organization	2.91e-02	1.00e+00	5.083	1	2	36
GO:0005524	ATP binding	3.00e-02	1.00e+00	2.037	3	23	892
GO:0042802	identical protein binding	3.17e-02	1.00e+00	2.786	2	7	354
GO:0006283	transcription-coupled nucleotide-excision repair	3.23e-02	1.00e+00	4.931	1	6	40
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.23e-02	1.00e+00	4.931	1	2	40
GO:0003684	damaged DNA binding	3.31e-02	1.00e+00	4.896	1	9	41
GO:0032481	positive regulation of type I interferon production	3.87e-02	1.00e+00	4.668	1	5	48
GO:0006334	nucleosome assembly	4.10e-02	1.00e+00	4.581	1	4	51
GO:0006368	transcription elongation from RNA polymerase II promoter	4.18e-02	1.00e+00	4.553	1	3	52
GO:0006915	apoptotic process	4.18e-02	1.00e+00	2.570	2	21	411
GO:0006289	nucleotide-excision repair	4.26e-02	1.00e+00	4.525	1	9	53
GO:0006338	chromatin remodeling	4.42e-02	1.00e+00	4.472	1	2	55
GO:0005681	spliceosomal complex	4.42e-02	1.00e+00	4.472	1	2	55
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	5	61
GO:0005200	structural constituent of cytoskeleton	5.44e-02	1.00e+00	4.166	1	2	68
GO:0051082	unfolded protein binding	5.59e-02	1.00e+00	4.124	1	4	70
GO:0001649	osteoblast differentiation	5.91e-02	1.00e+00	4.044	1	2	74
GO:0005815	microtubule organizing center	6.14e-02	1.00e+00	3.987	1	1	77
GO:0000086	G2/M transition of mitotic cell cycle	7.68e-02	1.00e+00	3.653	1	5	97
GO:0006457	protein folding	7.68e-02	1.00e+00	3.653	1	4	97
GO:0000790	nuclear chromatin	8.59e-02	1.00e+00	3.485	1	3	109
GO:0003924	GTPase activity	9.35e-02	1.00e+00	3.359	1	3	119
GO:0006184	GTP catabolic process	1.02e-01	1.00e+00	3.231	1	3	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.11e-01	1.00e+00	3.104	1	2	142
GO:0005622	intracellular	1.13e-01	1.00e+00	3.073	1	1	145
GO:0006367	transcription initiation from RNA polymerase II promoter	1.25e-01	1.00e+00	2.922	1	4	161
GO:0007067	mitotic nuclear division	1.27e-01	1.00e+00	2.887	1	8	165
GO:0007283	spermatogenesis	1.30e-01	1.00e+00	2.861	1	2	168
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.794	1	6	176
GO:0005737	cytoplasm	1.43e-01	1.00e+00	0.891	4	50	2633
GO:0044281	small molecule metabolic process	1.47e-01	1.00e+00	1.532	2	32	844
GO:0005525	GTP binding	1.50e-01	1.00e+00	2.631	1	5	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.55e-01	1.00e+00	2.588	1	1	203
GO:0043234	protein complex	1.60e-01	1.00e+00	2.539	1	8	210
GO:0043231	intracellular membrane-bounded organelle	1.65e-01	1.00e+00	2.485	1	7	218
GO:0005813	centrosome	1.65e-01	1.00e+00	2.492	1	8	217
GO:0006200	ATP catabolic process	1.66e-01	1.00e+00	2.479	1	8	219
GO:0003723	RNA binding	1.85e-01	1.00e+00	2.305	1	11	247
GO:0005515	protein binding	2.10e-01	1.00e+00	0.566	5	76	4124
GO:0006351	transcription, DNA-templated	2.18e-01	1.00e+00	1.182	2	9	1076
GO:0006366	transcription from RNA polymerase II promoter	2.48e-01	1.00e+00	1.840	1	6	341
GO:0005794	Golgi apparatus	2.94e-01	1.00e+00	1.556	1	5	415
GO:0045087	innate immune response	3.16e-01	1.00e+00	1.433	1	7	452
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.21e-01	1.00e+00	0.922	1	8	644
GO:0005739	mitochondrion	4.28e-01	1.00e+00	0.889	1	11	659
GO:0044822	poly(A) RNA binding	4.95e-01	1.00e+00	0.611	1	25	799
GO:0003677	DNA binding	5.58e-01	1.00e+00	0.366	1	18	947

Wolf-ratios-Mammosphere-Adherent

reg-snw-7407

Statistics

Genes (8)

Interactions (14)

Related GO terms (139)