Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.943 | 8.16e-16 | 2.09e-03 | 3.54e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
RUVBL1 | 8607 | 17 | 0.720 | 1.013 | 343 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
RPS11 | 6205 | 36 | 0.993 | 1.113 | 175 | Yes | - |
BCL6 | 604 | 1 | 0.496 | 0.943 | 92 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
RUVBL2 | 10856 | 5 | 0.693 | 1.003 | 345 | Yes | - |
[ YY1 ] | 7528 | 1 | 0.359 | 0.943 | 114 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
RPS11 | 6205 | RUVBL2 | 10856 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid |
ACTB | 60 | RUVBL1 | 8607 | pp | -- | int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast |
PSMD11 | 5717 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPSA | 3921 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid |
YY1 | 7528 | RUVBL1 | 8607 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association), MI:0407(direct interaction); int.I2D: BioGrid |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
RUVBL1 | 8607 | RUVBL2 | 10856 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd; int.Ravasi: -; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association) |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | YY1 | 7528 | pp | -- | int.Intact: MI:0914(association) |
PSMD11 | 5717 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
PSMD3 | 5709 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
YY1 | 7528 | RUVBL2 | 10856 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association), MI:0407(direct interaction); int.I2D: BioGrid |
BCL6 | 604 | YY1 | 7528 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, IntAct |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0035267 | NuA4 histone acetyltransferase complex | 2.07e-07 | 2.99e-03 | 7.893 | 3 | 4 | 14 |
GO:0031011 | Ino80 complex | 2.07e-07 | 2.99e-03 | 7.893 | 3 | 3 | 14 |
GO:0005654 | nucleoplasm | 8.95e-07 | 1.29e-02 | 3.036 | 8 | 76 | 1082 |
GO:0016071 | mRNA metabolic process | 9.83e-07 | 1.42e-02 | 4.637 | 5 | 31 | 223 |
GO:0016070 | RNA metabolic process | 1.63e-06 | 2.35e-02 | 4.489 | 5 | 32 | 247 |
GO:0016032 | viral process | 3.44e-06 | 4.96e-02 | 3.640 | 6 | 55 | 534 |
GO:0000082 | G1/S transition of mitotic cell cycle | 7.28e-06 | 1.05e-01 | 4.896 | 4 | 32 | 149 |
GO:0006521 | regulation of cellular amino acid metabolic process | 1.09e-05 | 1.58e-01 | 6.057 | 3 | 17 | 50 |
GO:0000502 | proteasome complex | 1.72e-05 | 2.47e-01 | 5.843 | 3 | 17 | 58 |
GO:0000812 | Swr1 complex | 2.09e-05 | 3.02e-01 | 8.116 | 2 | 3 | 8 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2.31e-05 | 3.33e-01 | 5.701 | 3 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.42e-05 | 3.49e-01 | 5.678 | 3 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.02e-05 | 4.36e-01 | 5.571 | 3 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 3.29e-05 | 4.75e-01 | 5.531 | 3 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.57e-05 | 5.15e-01 | 5.491 | 3 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 3.72e-05 | 5.37e-01 | 5.472 | 3 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 4.35e-05 | 6.27e-01 | 5.397 | 3 | 23 | 79 |
GO:0043968 | histone H2A acetylation | 4.92e-05 | 7.10e-01 | 7.531 | 2 | 3 | 12 |
GO:0005838 | proteasome regulatory particle | 4.92e-05 | 7.10e-01 | 7.531 | 2 | 7 | 12 |
GO:0006281 | DNA repair | 6.59e-05 | 9.50e-01 | 4.088 | 4 | 18 | 261 |
GO:0016363 | nuclear matrix | 6.64e-05 | 9.57e-01 | 5.193 | 3 | 12 | 91 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 6.86e-05 | 9.89e-01 | 5.177 | 3 | 21 | 92 |
GO:0003678 | DNA helicase activity | 1.01e-04 | 1.00e+00 | 7.028 | 2 | 3 | 17 |
GO:0022624 | proteasome accessory complex | 1.01e-04 | 1.00e+00 | 7.028 | 2 | 8 | 17 |
GO:0030529 | ribonucleoprotein complex | 1.23e-04 | 1.00e+00 | 4.893 | 3 | 8 | 112 |
GO:0000209 | protein polyubiquitination | 1.37e-04 | 1.00e+00 | 4.843 | 3 | 20 | 116 |
GO:0006325 | chromatin organization | 1.44e-04 | 1.00e+00 | 4.818 | 3 | 5 | 118 |
GO:0010467 | gene expression | 1.99e-04 | 1.00e+00 | 3.052 | 5 | 59 | 669 |
GO:0071339 | MLL1 complex | 2.60e-04 | 1.00e+00 | 6.361 | 2 | 3 | 27 |
GO:0043967 | histone H4 acetylation | 2.60e-04 | 1.00e+00 | 6.361 | 2 | 3 | 27 |
GO:0016020 | membrane | 2.61e-04 | 1.00e+00 | 2.208 | 7 | 90 | 1681 |
GO:0042981 | regulation of apoptotic process | 2.92e-04 | 1.00e+00 | 4.472 | 3 | 24 | 150 |
GO:0000278 | mitotic cell cycle | 3.13e-04 | 1.00e+00 | 3.505 | 4 | 48 | 391 |
GO:0034644 | cellular response to UV | 3.22e-04 | 1.00e+00 | 6.209 | 2 | 5 | 30 |
GO:0070062 | extracellular vesicular exosome | 3.39e-04 | 1.00e+00 | 1.887 | 8 | 104 | 2400 |
GO:0034641 | cellular nitrogen compound metabolic process | 4.29e-04 | 1.00e+00 | 4.283 | 3 | 20 | 171 |
GO:0031490 | chromatin DNA binding | 5.18e-04 | 1.00e+00 | 5.868 | 2 | 3 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 5.45e-04 | 1.00e+00 | 5.830 | 2 | 4 | 39 |
GO:0032508 | DNA duplex unwinding | 6.03e-04 | 1.00e+00 | 5.758 | 2 | 3 | 41 |
GO:0003684 | damaged DNA binding | 8.61e-04 | 1.00e+00 | 5.501 | 2 | 7 | 49 |
GO:0040008 | regulation of growth | 8.97e-04 | 1.00e+00 | 5.472 | 2 | 5 | 50 |
GO:0043380 | regulation of memory T cell differentiation | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1.01e-03 | 1.00e+00 | 5.388 | 2 | 5 | 53 |
GO:0005634 | nucleus | 1.03e-03 | 1.00e+00 | 1.283 | 10 | 136 | 4559 |
GO:0000724 | double-strand break repair via homologous recombination | 1.08e-03 | 1.00e+00 | 5.334 | 2 | 3 | 55 |
GO:0007283 | spermatogenesis | 1.48e-03 | 1.00e+00 | 3.667 | 3 | 8 | 262 |
GO:0006310 | DNA recombination | 1.51e-03 | 1.00e+00 | 5.093 | 2 | 2 | 65 |
GO:0034696 | response to prostaglandin F | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0032764 | negative regulation of mast cell cytokine production | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0006403 | RNA localization | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0045629 | negative regulation of T-helper 2 cell differentiation | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0003994 | aconitate hydratase activity | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 |
GO:0005515 | protein binding | 2.00e-03 | 1.00e+00 | 1.019 | 11 | 184 | 6024 |
GO:0019083 | viral transcription | 2.33e-03 | 1.00e+00 | 4.776 | 2 | 10 | 81 |
GO:0006415 | translational termination | 2.69e-03 | 1.00e+00 | 4.673 | 2 | 10 | 87 |
GO:0071733 | transcriptional activation by promoter-enhancer looping | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0071899 | negative regulation of estrogen receptor binding | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0048294 | negative regulation of isotype switching to IgE isotypes | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 |
GO:0005829 | cytosol | 2.99e-03 | 1.00e+00 | 1.638 | 7 | 132 | 2496 |
GO:0006414 | translational elongation | 3.06e-03 | 1.00e+00 | 4.576 | 2 | 13 | 93 |
GO:0043141 | ATP-dependent 5'-3' DNA helicase activity | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0002634 | regulation of germinal center formation | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0042092 | type 2 immune response | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 3.81e-03 | 1.00e+00 | 4.415 | 2 | 10 | 104 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0071169 | establishment of protein localization to chromatin | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 4.56e-03 | 1.00e+00 | 4.283 | 2 | 11 | 114 |
GO:0019058 | viral life cycle | 4.64e-03 | 1.00e+00 | 4.270 | 2 | 13 | 115 |
GO:0002903 | negative regulation of B cell apoptotic process | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 3 | 6 |
GO:0006101 | citrate metabolic process | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 |
GO:0043066 | negative regulation of apoptotic process | 5.79e-03 | 1.00e+00 | 2.973 | 3 | 31 | 424 |
GO:0006413 | translational initiation | 5.98e-03 | 1.00e+00 | 4.082 | 2 | 17 | 131 |
GO:0000028 | ribosomal small subunit assembly | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 2 | 7 |
GO:0003735 | structural constituent of ribosome | 6.52e-03 | 1.00e+00 | 4.018 | 2 | 10 | 137 |
GO:0016887 | ATPase activity | 6.80e-03 | 1.00e+00 | 3.986 | 2 | 7 | 140 |
GO:0006457 | protein folding | 7.09e-03 | 1.00e+00 | 3.956 | 2 | 7 | 143 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 4 | 8 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0002467 | germinal center formation | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 2 | 8 |
GO:0006974 | cellular response to DNA damage stimulus | 7.87e-03 | 1.00e+00 | 3.877 | 2 | 8 | 151 |
GO:0044267 | cellular protein metabolic process | 7.89e-03 | 1.00e+00 | 2.812 | 3 | 29 | 474 |
GO:0010225 | response to UV-C | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0000400 | four-way junction DNA binding | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 9 |
GO:0032319 | regulation of Rho GTPase activity | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 9 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 1 | 10 |
GO:0051272 | positive regulation of cellular component movement | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0035024 | negative regulation of Rho protein signal transduction | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 4 | 11 |
GO:0031625 | ubiquitin protein ligase binding | 1.08e-02 | 1.00e+00 | 3.640 | 2 | 14 | 178 |
GO:0001953 | negative regulation of cell-matrix adhesion | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 |
GO:0005730 | nucleolus | 1.11e-02 | 1.00e+00 | 1.757 | 5 | 69 | 1641 |
GO:0005662 | DNA replication factor A complex | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 3 | 13 |
GO:0006915 | apoptotic process | 1.21e-02 | 1.00e+00 | 2.584 | 3 | 33 | 555 |
GO:0048821 | erythrocyte development | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 15 |
GO:0035066 | positive regulation of histone acetylation | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 16 |
GO:0051276 | chromosome organization | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 16 |
GO:0048593 | camera-type eye morphogenesis | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 |
GO:0071392 | cellular response to estradiol stimulus | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 18 |
GO:0035861 | site of double-strand break | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 18 |
GO:0005657 | replication fork | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 18 |
GO:0005839 | proteasome core complex | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 8 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0005719 | nuclear euchromatin | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 2 | 19 |
GO:0001227 | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 |
GO:0004298 | threonine-type endopeptidase activity | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 8 | 19 |
GO:0006412 | translation | 1.76e-02 | 1.00e+00 | 3.270 | 2 | 20 | 230 |
GO:0006298 | mismatch repair | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 3 | 20 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 5 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 4 | 21 |
GO:0044281 | small molecule metabolic process | 1.91e-02 | 1.00e+00 | 1.874 | 4 | 58 | 1211 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 4 | 23 |
GO:0005844 | polysome | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 |
GO:0000060 | protein import into nucleus, translocation | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 5 | 24 |
GO:0034080 | CENP-A containing nucleosome assembly | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 1 | 25 |
GO:0000722 | telomere maintenance via recombination | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 5 | 25 |
GO:0031519 | PcG protein complex | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 4 | 25 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 2.28e-02 | 1.00e+00 | 3.071 | 2 | 8 | 264 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 3 | 26 |
GO:0004003 | ATP-dependent DNA helicase activity | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 2 | 27 |
GO:0019843 | rRNA binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 3 | 27 |
GO:0043022 | ribosome binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 4 | 27 |
GO:0006099 | tricarboxylic acid cycle | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.58e-02 | 1.00e+00 | 5.258 | 1 | 1 | 29 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 7 | 30 |
GO:0001895 | retina homeostasis | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 1 | 34 |
GO:0030890 | positive regulation of B cell proliferation | 3.11e-02 | 1.00e+00 | 4.986 | 1 | 1 | 35 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.11e-02 | 1.00e+00 | 4.986 | 1 | 3 | 35 |
GO:0034332 | adherens junction organization | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.29e-02 | 1.00e+00 | 4.906 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 3.29e-02 | 1.00e+00 | 4.906 | 1 | 3 | 37 |
GO:0070527 | platelet aggregation | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 2 | 38 |
GO:0006351 | transcription, DNA-templated | 3.44e-02 | 1.00e+00 | 1.618 | 4 | 31 | 1446 |
GO:0000781 | chromosome, telomeric region | 3.46e-02 | 1.00e+00 | 4.830 | 1 | 3 | 39 |
GO:0003723 | RNA binding | 3.68e-02 | 1.00e+00 | 2.698 | 2 | 20 | 342 |
GO:0021762 | substantia nigra development | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 2 | 44 |
GO:0050727 | regulation of inflammatory response | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 3 | 45 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 7 | 46 |
GO:0005925 | focal adhesion | 4.16e-02 | 1.00e+00 | 2.600 | 2 | 19 | 366 |
GO:0007266 | Rho protein signal transduction | 4.16e-02 | 1.00e+00 | 4.561 | 1 | 2 | 47 |
GO:0000902 | cell morphogenesis | 4.33e-02 | 1.00e+00 | 4.501 | 1 | 2 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 3 | 50 |
GO:0030183 | B cell differentiation | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 2 | 54 |
GO:0045216 | cell-cell junction organization | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 2 | 54 |
GO:0000723 | telomere maintenance | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 6 | 56 |
GO:0005840 | ribosome | 5.11e-02 | 1.00e+00 | 4.258 | 1 | 1 | 58 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 5.19e-02 | 1.00e+00 | 4.233 | 1 | 1 | 59 |
GO:0019903 | protein phosphatase binding | 5.45e-02 | 1.00e+00 | 4.161 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 5.45e-02 | 1.00e+00 | 4.161 | 1 | 4 | 62 |
GO:0006338 | chromatin remodeling | 5.79e-02 | 1.00e+00 | 4.071 | 1 | 5 | 66 |
GO:0006289 | nucleotide-excision repair | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 11 | 68 |
GO:0034329 | cell junction assembly | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 5 | 68 |
GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 6.22e-02 | 1.00e+00 | 3.966 | 1 | 1 | 71 |
GO:0006334 | nucleosome assembly | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 2 | 72 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 6.47e-02 | 1.00e+00 | 3.906 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.56e-02 | 1.00e+00 | 3.887 | 1 | 2 | 75 |
GO:0050776 | regulation of immune response | 6.64e-02 | 1.00e+00 | 3.868 | 1 | 1 | 76 |
GO:0009952 | anterior/posterior pattern specification | 7.23e-02 | 1.00e+00 | 3.741 | 1 | 1 | 83 |
GO:0047485 | protein N-terminus binding | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 5 | 86 |
GO:0016605 | PML body | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 3 | 88 |
GO:0006928 | cellular component movement | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 6 | 92 |
GO:0071456 | cellular response to hypoxia | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 6 | 92 |
GO:0051082 | unfolded protein binding | 8.07e-02 | 1.00e+00 | 3.576 | 1 | 5 | 93 |
GO:0014069 | postsynaptic density | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 4 | 105 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 9.12e-02 | 1.00e+00 | 1.961 | 2 | 16 | 570 |
GO:0005815 | microtubule organizing center | 9.39e-02 | 1.00e+00 | 3.347 | 1 | 5 | 109 |
GO:0030308 | negative regulation of cell growth | 9.48e-02 | 1.00e+00 | 3.334 | 1 | 6 | 110 |
GO:0072562 | blood microparticle | 9.56e-02 | 1.00e+00 | 3.321 | 1 | 3 | 111 |
GO:0044237 | cellular metabolic process | 1.01e-01 | 1.00e+00 | 3.245 | 1 | 5 | 117 |
GO:0007219 | Notch signaling pathway | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 1.04e-01 | 1.00e+00 | 3.197 | 1 | 9 | 121 |
GO:0030036 | actin cytoskeleton organization | 1.05e-01 | 1.00e+00 | 3.173 | 1 | 5 | 123 |
GO:0005524 | ATP binding | 1.05e-01 | 1.00e+00 | 1.359 | 3 | 60 | 1298 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.10e-01 | 1.00e+00 | 3.104 | 1 | 9 | 129 |
GO:0061024 | membrane organization | 1.23e-01 | 1.00e+00 | 2.936 | 1 | 7 | 145 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 1.29e-01 | 1.00e+00 | 1.666 | 2 | 11 | 699 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.39e-01 | 1.00e+00 | 2.749 | 1 | 7 | 165 |
GO:0030424 | axon | 1.40e-01 | 1.00e+00 | 2.741 | 1 | 4 | 166 |
GO:0044212 | transcription regulatory region DNA binding | 1.41e-01 | 1.00e+00 | 2.723 | 1 | 6 | 168 |
GO:0005667 | transcription factor complex | 1.47e-01 | 1.00e+00 | 2.664 | 1 | 4 | 175 |
GO:0003714 | transcription corepressor activity | 1.49e-01 | 1.00e+00 | 2.640 | 1 | 8 | 178 |
GO:0032403 | protein complex binding | 1.53e-01 | 1.00e+00 | 2.600 | 1 | 10 | 183 |
GO:0005622 | intracellular | 1.71e-01 | 1.00e+00 | 2.422 | 1 | 6 | 207 |
GO:0007067 | mitotic nuclear division | 1.86e-01 | 1.00e+00 | 2.289 | 1 | 14 | 227 |
GO:0005759 | mitochondrial matrix | 1.87e-01 | 1.00e+00 | 2.283 | 1 | 14 | 228 |
GO:0003713 | transcription coactivator activity | 1.94e-01 | 1.00e+00 | 2.227 | 1 | 10 | 237 |
GO:0004842 | ubiquitin-protein transferase activity | 2.07e-01 | 1.00e+00 | 2.121 | 1 | 6 | 255 |
GO:0043065 | positive regulation of apoptotic process | 2.16e-01 | 1.00e+00 | 2.050 | 1 | 10 | 268 |
GO:0006954 | inflammatory response | 2.23e-01 | 1.00e+00 | 2.002 | 1 | 7 | 277 |
GO:0019899 | enzyme binding | 2.23e-01 | 1.00e+00 | 2.002 | 1 | 12 | 277 |
GO:0008270 | zinc ion binding | 2.25e-01 | 1.00e+00 | 1.154 | 2 | 12 | 997 |
GO:0005856 | cytoskeleton | 2.33e-01 | 1.00e+00 | 1.931 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.34e-01 | 1.00e+00 | 1.926 | 1 | 15 | 292 |
GO:0005737 | cytoplasm | 2.35e-01 | 1.00e+00 | 0.558 | 5 | 110 | 3767 |
GO:0043234 | protein complex | 2.36e-01 | 1.00e+00 | 1.911 | 1 | 18 | 295 |
GO:0016567 | protein ubiquitination | 2.36e-01 | 1.00e+00 | 1.911 | 1 | 5 | 295 |
GO:0030154 | cell differentiation | 2.40e-01 | 1.00e+00 | 1.882 | 1 | 5 | 301 |
GO:0044822 | poly(A) RNA binding | 2.46e-01 | 1.00e+00 | 1.071 | 2 | 49 | 1056 |
GO:0019901 | protein kinase binding | 2.51e-01 | 1.00e+00 | 1.807 | 1 | 21 | 317 |
GO:0043231 | intracellular membrane-bounded organelle | 2.52e-01 | 1.00e+00 | 1.803 | 1 | 9 | 318 |
GO:0007411 | axon guidance | 2.52e-01 | 1.00e+00 | 1.798 | 1 | 13 | 319 |
GO:0005813 | centrosome | 2.57e-01 | 1.00e+00 | 1.767 | 1 | 14 | 326 |
GO:0003682 | chromatin binding | 2.58e-01 | 1.00e+00 | 1.762 | 1 | 11 | 327 |
GO:0043565 | sequence-specific DNA binding | 2.71e-01 | 1.00e+00 | 1.681 | 1 | 6 | 346 |
GO:0008285 | negative regulation of cell proliferation | 2.75e-01 | 1.00e+00 | 1.652 | 1 | 11 | 353 |
GO:0007155 | cell adhesion | 2.86e-01 | 1.00e+00 | 1.588 | 1 | 6 | 369 |
GO:0045892 | negative regulation of transcription, DNA-templated | 3.15e-01 | 1.00e+00 | 1.426 | 1 | 15 | 413 |
GO:0007596 | blood coagulation | 3.41e-01 | 1.00e+00 | 1.286 | 1 | 18 | 455 |
GO:0042802 | identical protein binding | 3.58e-01 | 1.00e+00 | 1.197 | 1 | 20 | 484 |
GO:0045087 | innate immune response | 4.22e-01 | 1.00e+00 | 0.896 | 1 | 24 | 596 |
GO:0005794 | Golgi apparatus | 4.30e-01 | 1.00e+00 | 0.863 | 1 | 15 | 610 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 5.19e-01 | 1.00e+00 | 0.492 | 1 | 19 | 789 |
GO:0005615 | extracellular space | 5.91e-01 | 1.00e+00 | 0.213 | 1 | 17 | 957 |
GO:0005739 | mitochondrion | 6.06e-01 | 1.00e+00 | 0.153 | 1 | 28 | 998 |
GO:0003677 | DNA binding | 6.83e-01 | 1.00e+00 | -0.135 | 1 | 28 | 1218 |
GO:0046872 | metal ion binding | 7.09e-01 | 1.00e+00 | -0.236 | 1 | 25 | 1307 |
GO:0005886 | plasma membrane | 9.23e-01 | 1.00e+00 | -1.219 | 1 | 45 | 2582 |