meta-int-snw-5792

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-5792 wolf-screen-ratio-mammosphere-adherent 0.953 3.19e-16 1.66e-03 3.00e-02 12 10
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-1434 wolf-screen-ratio-mammosphere-adherent 0.865 2.23e-07 1.35e-03 2.78e-03 9 7
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
reg-snw-5686 wolf-screen-ratio-mammosphere-adherent 0.878 1.30e-07 1.01e-03 2.15e-03 5 4
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-5792 subnetwork

Genes (39)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
POLR2F 5435 620.8910.95626Yes-
RET 5979 8-0.7140.95340--
CSE1L 1434 410.3040.86554Yes-
VARS 7407 860.5491.002204Yes-
DDX51 317781 530.0590.823210Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
CCNA2 890 540.5500.973246Yes-
PSMD1 5707 860.8360.830118Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
PRMT3 10196 490.4310.81526--
PSMA5 5686 350.3780.87833--
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
TREX1 11277 51-0.0510.88291Yes-
BCAR1 9564 8-0.4540.95381-Yes
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
PTPRF 5792 8-0.3440.95328--
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-

Interactions (186)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMA5 5686 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
CSE1L 1434 PSMD14 10213 pd < reg.ITFP.txt: no annot
CSE1L 1434 RAN 5901 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG;
int.HPRD: in vitro
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
PSMA5 5686 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMA5 5686 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BIND_Yeast, IntAct_Fly, Krogan_Core
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
CCNA2 890 CSE1L 1434 pd > reg.ITFP.txt: no annot
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPA1 6117 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
PTPRF 5792 BCAR1 9564 pp -- int.I2D: HPRD;
int.HPRD: in vivo
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMA5 5686 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastHigh, Yu_GoldStd, Krogan_Core, MINT_Yeast
CSE1L 1434 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PTPRF 5792 RET 5979 pp -- int.I2D: BioGrid
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA5 5686 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, YeastHigh
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
PSMA5 5686 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD6 9861 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA5 5686 POLE4 56655 pd < reg.ITFP.txt: no annot
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMA5 5686 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA3 5684 PSMA5 5686 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Mouse, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core, Tarassov_PCA
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMB3 5691 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastHigh
CCNA2 890 RPA1 6117 pp -- int.I2D: BioGrid
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 BCAR1 9564 pp -- int.I2D: MINT

Related GO terms (451)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.88e-251.29e-206.494142465
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.48e-244.04e-206.387142470
GO:0006521regulation of cellular amino acid metabolic process2.93e-244.78e-206.766132150
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.81e-249.49e-206.307142474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.58e-232.57e-196.213142579
GO:0000502proteasome complex2.57e-234.20e-196.551132258
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.33e-222.16e-186.387132265
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.88e-221.12e-176.220132373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.46e-212.38e-176.143132377
GO:0000082G1/S transition of mitotic cell cycle2.87e-214.68e-175.3871533150
GO:0005654nucleoplasm2.17e-203.55e-163.25625831095
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.33e-203.80e-165.855132394
GO:0042981regulation of apoptotic process2.25e-193.68e-155.2781426151
GO:0000278mitotic cell cycle2.48e-194.05e-154.2421852398
GO:0000209protein polyubiquitination4.12e-196.72e-155.5511321116
GO:0005839proteasome core complex2.12e-173.47e-137.53981118
GO:0016071mRNA metabolic process5.85e-179.55e-134.7151434223
GO:0004298threonine-type endopeptidase activity6.09e-179.94e-137.38781120
GO:0010467gene expression1.09e-161.78e-123.5711958669
GO:0034641cellular nitrogen compound metabolic process1.17e-161.91e-124.9421325177
GO:0016070RNA metabolic process2.46e-164.02e-124.5681434247
GO:0016032viral process1.38e-152.26e-113.7201755540
GO:0005829cytosol9.62e-141.57e-092.141271252562
GO:0043066negative regulation of apoptotic process1.17e-111.91e-073.6511330433
GO:0006915apoptotic process2.37e-113.86e-073.3591434571
GO:0070062extracellular vesicular exosome6.90e-111.13e-061.99724982516
GO:0022624proteasome accessory complex3.62e-105.90e-066.9445917
GO:0019773proteasome core complex, alpha-subunit complex1.93e-093.16e-057.709458
GO:0044281small molecule metabolic process1.47e-082.40e-042.37016571295
GO:0005730nucleolus8.71e-081.42e-032.07917701684
GO:0005634nucleus1.81e-062.96e-021.172261314828
GO:0006281DNA repair2.64e-064.32e-023.472722264
GO:0005838proteasome regulatory particle2.73e-064.46e-026.7093712
GO:0035267NuA4 histone acetyltransferase complex4.51e-067.36e-026.4873414
GO:0016020membrane5.36e-068.75e-021.84615801746
GO:0006298mismatch repair1.40e-052.28e-015.9723620
GO:0005515protein binding1.45e-052.36e-010.935281726127
GO:0006310DNA recombination1.91e-053.12e-014.6434467
GO:0000730DNA recombinase assembly5.54e-059.04e-017.387235
GO:0000812Swr1 complex1.54e-041.00e+006.709238
GO:0006283transcription-coupled nucleotide-excision repair1.78e-041.00e+004.7703846
GO:0003684damaged DNA binding2.43e-041.00e+004.62231151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding2.88e-041.00e+004.5393554
GO:0000724double-strand break repair via homologous recombination3.38e-041.00e+004.4613657
GO:0043968histone H2A acetylation3.62e-041.00e+006.1242312
GO:0005662DNA replication factor A complex4.27e-041.00e+006.0092313
GO:0030234enzyme regulator activity4.27e-041.00e+006.0092313
GO:0031011Ino80 complex4.97e-041.00e+005.9022314
GO:0006289nucleotide-excision repair5.93e-041.00e+004.18531269
GO:0003697single-stranded DNA binding5.93e-041.00e+004.1853969
GO:0042176regulation of protein catabolic process6.54e-041.00e+005.7092316
GO:0006259DNA metabolic process9.27e-041.00e+005.4612319
GO:0003678DNA helicase activity9.27e-041.00e+005.4612319
GO:0000718nucleotide-excision repair, DNA damage removal1.14e-031.00e+005.3172521
GO:0006297nucleotide-excision repair, DNA gap filling1.25e-031.00e+005.2502522
GO:0032201telomere maintenance via semi-conservative replication1.25e-031.00e+005.2502722
GO:0043044ATP-dependent chromatin remodeling1.36e-031.00e+005.1852423
GO:0016363nuclear matrix1.37e-031.00e+003.77031192
GO:0006611protein export from nucleus1.61e-031.00e+005.0652425
GO:0000722telomere maintenance via recombination1.74e-031.00e+005.0092726
GO:0071339MLL1 complex1.88e-031.00e+004.9542327
GO:0043022ribosome binding2.02e-031.00e+004.9022328
GO:0043967histone H4 acetylation2.02e-031.00e+004.9022328
GO:0031492nucleosomal DNA binding2.02e-031.00e+004.9022428
GO:0007067mitotic nuclear division2.18e-031.00e+002.857413231
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.39e-031.00e+008.709111
GO:0070335aspartate binding2.39e-031.00e+008.709111
GO:0008262importin-alpha export receptor activity2.39e-031.00e+008.709111
GO:0008541proteasome regulatory particle, lid subcomplex2.39e-031.00e+008.709111
GO:0032558adenyl deoxyribonucleotide binding2.39e-031.00e+008.709111
GO:0004151dihydroorotase activity2.39e-031.00e+008.709111
GO:0000054ribosomal subunit export from nucleus2.39e-031.00e+008.709111
GO:0004070aspartate carbamoyltransferase activity2.39e-031.00e+008.709111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.39e-031.00e+008.709111
GO:0005737cytoplasm2.42e-031.00e+000.92218983976
GO:0006271DNA strand elongation involved in DNA replication2.48e-031.00e+004.7552931
GO:0030529ribonucleoprotein complex2.53e-031.00e+003.46138114
GO:0006325chromatin organization3.13e-031.00e+003.35134123
GO:0006260DNA replication3.28e-031.00e+003.328312125
GO:0006284base-excision repair3.90e-031.00e+004.4242739
GO:0032508DNA duplex unwinding4.51e-031.00e+004.3172442
GO:0004832valine-tRNA ligase activity4.77e-031.00e+007.709112
GO:0097021lymphocyte migration into lymphoid organs4.77e-031.00e+007.709112
GO:0006407rRNA export from nucleus4.77e-031.00e+007.709112
GO:0007497posterior midgut development4.77e-031.00e+007.709112
GO:0006438valyl-tRNA aminoacylation4.77e-031.00e+007.709112
GO:0000105histidine biosynthetic process4.77e-031.00e+007.709112
GO:00082963'-5'-exodeoxyribonuclease activity4.77e-031.00e+007.709112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.77e-031.00e+007.709112
GO:0005055laminin receptor activity4.77e-031.00e+007.709112
GO:0001838embryonic epithelial tube formation4.77e-031.00e+007.709112
GO:0070409carbamoyl phosphate biosynthetic process4.77e-031.00e+007.709112
GO:0016887ATPase activity4.87e-031.00e+003.12437144
GO:0031100organ regeneration6.34e-031.00e+004.0652450
GO:0040008regulation of growth6.59e-031.00e+004.0372351
GO:0000398mRNA splicing, via spliceosome7.10e-031.00e+002.928312165
GO:0071899negative regulation of estrogen receptor binding7.15e-031.00e+007.124113
GO:0014042positive regulation of neuron maturation7.15e-031.00e+007.124113
GO:0072300positive regulation of metanephric glomerulus development7.15e-031.00e+007.124113
GO:0071733transcriptional activation by promoter-enhancer looping7.15e-031.00e+007.124113
GO:0000056ribosomal small subunit export from nucleus7.15e-031.00e+007.124113
GO:1900121negative regulation of receptor binding7.15e-031.00e+007.124113
GO:0044205'de novo' UMP biosynthetic process7.15e-031.00e+007.124113
GO:0061146Peyer's patch morphogenesis7.15e-031.00e+007.124113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process7.15e-031.00e+007.124113
GO:0000723telomere maintenance8.74e-031.00e+003.8262859
GO:0032481positive regulation of type I interferon production9.32e-031.00e+003.7782661
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)9.52e-031.00e+006.709114
GO:0000212meiotic spindle organization9.52e-031.00e+006.709114
GO:003068690S preribosome9.52e-031.00e+006.709114
GO:0019788NEDD8 ligase activity9.52e-031.00e+006.709114
GO:0016274protein-arginine N-methyltransferase activity9.52e-031.00e+006.709114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity9.52e-031.00e+006.709114
GO:0004329formate-tetrahydrofolate ligase activity9.52e-031.00e+006.709114
GO:0043141ATP-dependent 5'-3' DNA helicase activity9.52e-031.00e+006.709114
GO:0034969histone arginine methylation9.52e-031.00e+006.709114
GO:0006543glutamine catabolic process9.52e-031.00e+006.709114
GO:0009396folic acid-containing compound biosynthetic process9.52e-031.00e+006.709114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity9.52e-031.00e+006.709114
GO:0031467Cul7-RING ubiquitin ligase complex9.52e-031.00e+006.709114
GO:0000055ribosomal large subunit export from nucleus9.52e-031.00e+006.709114
GO:0035799ureter maturation9.52e-031.00e+006.709114
GO:0008853exodeoxyribonuclease III activity9.52e-031.00e+006.709114
GO:0006302double-strand break repair9.61e-031.00e+003.7552862
GO:0051414response to cortisol1.19e-021.00e+006.387115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.19e-021.00e+006.387125
GO:0042256mature ribosome assembly1.19e-021.00e+006.387115
GO:0001940male pronucleus1.19e-021.00e+006.387115
GO:0009086methionine biosynthetic process1.19e-021.00e+006.387115
GO:0032407MutSalpha complex binding1.19e-021.00e+006.387115
GO:2000001regulation of DNA damage checkpoint1.19e-021.00e+006.387115
GO:0008622epsilon DNA polymerase complex1.19e-021.00e+006.387115
GO:0031461cullin-RING ubiquitin ligase complex1.19e-021.00e+006.387115
GO:0071169establishment of protein localization to chromatin1.19e-021.00e+006.387115
GO:0043248proteasome assembly1.19e-021.00e+006.387115
GO:0030891VCB complex1.19e-021.00e+006.387125
GO:0050851antigen receptor-mediated signaling pathway1.19e-021.00e+006.387115
GO:0005827polar microtubule1.19e-021.00e+006.387115
GO:0005638lamin filament1.19e-021.00e+006.387115
GO:0061133endopeptidase activator activity1.19e-021.00e+006.387115
GO:0003924GTPase activity1.25e-021.00e+002.62939203
GO:0005524ATP binding1.33e-021.00e+001.3068461354
GO:0043023ribosomal large subunit binding1.43e-021.00e+006.124126
GO:0031466Cul5-RING ubiquitin ligase complex1.43e-021.00e+006.124116
GO:0048012hepatocyte growth factor receptor signaling pathway1.43e-021.00e+006.124116
GO:0030957Tat protein binding1.43e-021.00e+006.124146
GO:0033619membrane protein proteolysis1.43e-021.00e+006.124116
GO:0046134pyrimidine nucleoside biosynthetic process1.43e-021.00e+006.124116
GO:0032405MutLalpha complex binding1.43e-021.00e+006.124126
GO:0008469histone-arginine N-methyltransferase activity1.43e-021.00e+006.124116
GO:0071013catalytic step 2 spliceosome1.53e-021.00e+003.4052779
GO:0006184GTP catabolic process1.55e-021.00e+002.51339220
GO:0010950positive regulation of endopeptidase activity1.66e-021.00e+005.902117
GO:0000028ribosomal small subunit assembly1.66e-021.00e+005.902117
GO:0002161aminoacyl-tRNA editing activity1.66e-021.00e+005.902127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.66e-021.00e+005.902117
GO:0001939female pronucleus1.66e-021.00e+005.902117
GO:0031462Cul2-RING ubiquitin ligase complex1.66e-021.00e+005.902127
GO:0035999tetrahydrofolate interconversion1.66e-021.00e+005.902117
GO:0035729cellular response to hepatocyte growth factor stimulus1.66e-021.00e+005.902117
GO:0072341modified amino acid binding1.66e-021.00e+005.902117
GO:0000930gamma-tubulin complex1.66e-021.00e+005.902117
GO:0007185transmembrane receptor protein tyrosine phosphatase signaling pathway1.66e-021.00e+005.902117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.66e-021.00e+005.902117
GO:0005681spliceosomal complex1.68e-021.00e+003.3342383
GO:0008380RNA splicing1.78e-021.00e+002.436313232
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.90e-021.00e+005.709128
GO:0001055RNA polymerase II activity1.90e-021.00e+005.709138
GO:0070688MLL5-L complex1.90e-021.00e+005.709118
GO:0045116protein neddylation1.90e-021.00e+005.709128
GO:0000800lateral element1.90e-021.00e+005.709118
GO:0006164purine nucleotide biosynthetic process1.90e-021.00e+005.709128
GO:0016605PML body2.03e-021.00e+003.1852592
GO:0005200structural constituent of cytoskeleton2.08e-021.00e+003.1702793
GO:0014075response to amine2.13e-021.00e+005.539119
GO:0045793positive regulation of cell size2.13e-021.00e+005.539129
GO:0006228UTP biosynthetic process2.13e-021.00e+005.539119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.13e-021.00e+005.539119
GO:0031000response to caffeine2.13e-021.00e+005.539129
GO:0070628proteasome binding2.36e-021.00e+005.3871110
GO:0046655folic acid metabolic process2.36e-021.00e+005.3871110
GO:0006450regulation of translational fidelity2.36e-021.00e+005.3871210
GO:0010569regulation of double-strand break repair via homologous recombination2.60e-021.00e+005.2501111
GO:0031571mitotic G1 DNA damage checkpoint2.60e-021.00e+005.2501311
GO:0042551neuron maturation2.60e-021.00e+005.2501211
GO:0033630positive regulation of cell adhesion mediated by integrin2.60e-021.00e+005.2501111
GO:0001054RNA polymerase I activity2.60e-021.00e+005.2501311
GO:0045120pronucleus2.60e-021.00e+005.2501111
GO:0033762response to glucagon2.60e-021.00e+005.2501111
GO:0035458cellular response to interferon-beta2.60e-021.00e+005.2501211
GO:0061136regulation of proteasomal protein catabolic process2.83e-021.00e+005.1241112
GO:00709353'-UTR-mediated mRNA stabilization2.83e-021.00e+005.1241212
GO:0005736DNA-directed RNA polymerase I complex2.83e-021.00e+005.1241312
GO:0048484enteric nervous system development2.83e-021.00e+005.1241112
GO:0042273ribosomal large subunit biogenesis3.06e-021.00e+005.0091413
GO:0060384innervation3.06e-021.00e+005.0091113
GO:0007158neuron cell-cell adhesion3.06e-021.00e+005.0091113
GO:0032479regulation of type I interferon production3.06e-021.00e+005.0091213
GO:0000738DNA catabolic process, exonucleolytic3.06e-021.00e+005.0091213
GO:0008266poly(U) RNA binding3.06e-021.00e+005.0091113
GO:0019058viral life cycle3.08e-021.00e+002.864210115
GO:0007020microtubule nucleation3.30e-021.00e+004.9021114
GO:0007095mitotic G2 DNA damage checkpoint3.30e-021.00e+004.9021114
GO:0043234protein complex3.45e-021.00e+002.065317300
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand3.53e-021.00e+004.8021215
GO:0035066positive regulation of histone acetylation3.53e-021.00e+004.8021115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.53e-021.00e+004.8021115
GO:0006261DNA-dependent DNA replication3.53e-021.00e+004.8021215
GO:0006200ATP catabolic process3.54e-021.00e+002.051314303
GO:0006511ubiquitin-dependent protein catabolic process3.69e-021.00e+002.72025127
GO:0005665DNA-directed RNA polymerase II, core complex3.76e-021.00e+004.7091416
GO:0050998nitric-oxide synthase binding3.76e-021.00e+004.7091116
GO:0048265response to pain3.76e-021.00e+004.7091116
GO:0001673male germ cell nucleus3.76e-021.00e+004.7091116
GO:0001056RNA polymerase III activity3.76e-021.00e+004.7091316
GO:00084083'-5' exonuclease activity3.76e-021.00e+004.7091216
GO:0030335positive regulation of cell migration3.85e-021.00e+002.68726130
GO:0006413translational initiation3.90e-021.00e+002.676212131
GO:0016477cell migration3.90e-021.00e+002.67626131
GO:0010243response to organonitrogen compound3.99e-021.00e+004.6221217
GO:0005666DNA-directed RNA polymerase III complex3.99e-021.00e+004.6221317
GO:0075733intracellular transport of virus3.99e-021.00e+004.6221217
GO:0007126meiotic nuclear division3.99e-021.00e+004.6221117
GO:0000790nuclear chromatin4.01e-021.00e+002.65427133
GO:0019901protein kinase binding4.06e-021.00e+001.972321320
GO:0070536protein K63-linked deubiquitination4.22e-021.00e+004.5391118
GO:0006386termination of RNA polymerase III transcription4.22e-021.00e+004.5391318
GO:0071392cellular response to estradiol stimulus4.22e-021.00e+004.5391118
GO:0006541glutamine metabolic process4.22e-021.00e+004.5391118
GO:0031122cytoplasmic microtubule organization4.22e-021.00e+004.5391218
GO:0035861site of double-strand break4.22e-021.00e+004.5391118
GO:0006385transcription elongation from RNA polymerase III promoter4.22e-021.00e+004.5391318
GO:0005001transmembrane receptor protein tyrosine phosphatase activity4.22e-021.00e+004.5391118
GO:0006303double-strand break repair via nonhomologous end joining4.22e-021.00e+004.5391318
GO:0000086G2/M transition of mitotic cell cycle4.23e-021.00e+002.61127137
GO:0005525GTP binding4.32e-021.00e+001.936311328
GO:0008283cell proliferation4.42e-021.00e+001.923312331
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.45e-021.00e+004.4611119
GO:0048863stem cell differentiation4.45e-021.00e+004.4611119
GO:0007088regulation of mitosis4.45e-021.00e+004.4611119
GO:0048873homeostasis of number of cells within a tissue4.67e-021.00e+004.3871120
GO:0005680anaphase-promoting complex4.67e-021.00e+004.3871420
GO:0005719nuclear euchromatin4.67e-021.00e+004.3871220
GO:0005813centrosome4.68e-021.00e+001.889312339
GO:0048010vascular endothelial growth factor receptor signaling pathway4.90e-021.00e+004.3171121
GO:0071364cellular response to epidermal growth factor stimulus4.90e-021.00e+004.3171121
GO:0006457protein folding4.92e-021.00e+002.49028149
GO:0033574response to testosterone5.13e-021.00e+004.2501222
GO:0030863cortical cytoskeleton5.13e-021.00e+004.2501122
GO:0036464cytoplasmic ribonucleoprotein granule5.13e-021.00e+004.2501422
GO:0007052mitotic spindle organization5.13e-021.00e+004.2501222
GO:0031463Cul3-RING ubiquitin ligase complex5.36e-021.00e+004.1851223
GO:0043236laminin binding5.36e-021.00e+004.1851123
GO:0006513protein monoubiquitination5.36e-021.00e+004.1851123
GO:0000794condensed nuclear chromosome5.58e-021.00e+004.1241224
GO:0006206pyrimidine nucleobase metabolic process5.58e-021.00e+004.1241224
GO:0008536Ran GTPase binding5.81e-021.00e+004.0651225
GO:0005844polysome5.81e-021.00e+004.0651425
GO:0017144drug metabolic process5.81e-021.00e+004.0651125
GO:0070979protein K11-linked ubiquitination6.04e-021.00e+004.0091326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.04e-021.00e+004.0091226
GO:0050770regulation of axonogenesis6.04e-021.00e+004.0091126
GO:0006730one-carbon metabolic process6.04e-021.00e+004.0091126
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.09e-021.00e+002.31725168
GO:0048008platelet-derived growth factor receptor signaling pathway6.26e-021.00e+003.9541127
GO:0004003ATP-dependent DNA helicase activity6.26e-021.00e+003.9541327
GO:0034080CENP-A containing nucleosome assembly6.26e-021.00e+003.9541227
GO:0007155cell adhesion6.34e-021.00e+001.70938384
GO:0019894kinesin binding6.48e-021.00e+003.9021128
GO:0019005SCF ubiquitin ligase complex6.71e-021.00e+003.8511129
GO:0003730mRNA 3'-UTR binding6.71e-021.00e+003.8511229
GO:0003887DNA-directed DNA polymerase activity6.71e-021.00e+003.8511329
GO:0071897DNA biosynthetic process6.71e-021.00e+003.8511229
GO:0031625ubiquitin protein ligase binding6.87e-021.00e+002.217213180
GO:00063707-methylguanosine mRNA capping6.93e-021.00e+003.8021430
GO:0050853B cell receptor signaling pathway6.93e-021.00e+003.8021130
GO:0006360transcription from RNA polymerase I promoter6.93e-021.00e+003.8021430
GO:0001755neural crest cell migration6.93e-021.00e+003.8021230
GO:0004714transmembrane receptor protein tyrosine kinase activity6.93e-021.00e+003.8021230
GO:0015629actin cytoskeleton7.07e-021.00e+002.19325183
GO:0007094mitotic spindle assembly checkpoint7.15e-021.00e+003.7551531
GO:0032403protein complex binding7.21e-021.00e+002.17827185
GO:0031397negative regulation of protein ubiquitination7.38e-021.00e+003.7091132
GO:0034644cellular response to UV7.38e-021.00e+003.7091532
GO:0005876spindle microtubule7.82e-021.00e+003.6221334
GO:0034332adherens junction organization8.26e-021.00e+003.5391136
GO:0004221ubiquitin thiolesterase activity8.26e-021.00e+003.5391236
GO:0001895retina homeostasis8.26e-021.00e+003.5391136
GO:0051084'de novo' posttranslational protein folding8.48e-021.00e+003.5001437
GO:0018107peptidyl-threonine phosphorylation8.48e-021.00e+003.5001137
GO:0010595positive regulation of endothelial cell migration8.70e-021.00e+003.4611138
GO:0070527platelet aggregation8.70e-021.00e+003.4611238
GO:0050681androgen receptor binding8.70e-021.00e+003.4611438
GO:0001657ureteric bud development8.92e-021.00e+003.4241139
GO:0006383transcription from RNA polymerase III promoter8.92e-021.00e+003.4241339
GO:0008026ATP-dependent helicase activity8.92e-021.00e+003.4241339
GO:0031490chromatin DNA binding8.92e-021.00e+003.4241239
GO:0022627cytosolic small ribosomal subunit8.92e-021.00e+003.4241339
GO:0032092positive regulation of protein binding8.92e-021.00e+003.4241339
GO:0007595lactation8.92e-021.00e+003.4241239
GO:0000781chromosome, telomeric region9.14e-021.00e+003.3871240
GO:0007015actin filament organization9.14e-021.00e+003.3871240
GO:0043195terminal bouton9.35e-021.00e+003.3511141
GO:0030521androgen receptor signaling pathway9.35e-021.00e+003.3511241
GO:0006418tRNA aminoacylation for protein translation9.57e-021.00e+003.3171542
GO:0030155regulation of cell adhesion9.57e-021.00e+003.3171342
GO:0014070response to organic cyclic compound9.79e-021.00e+003.2831343
GO:0048146positive regulation of fibroblast proliferation1.00e-011.00e+003.2501244
GO:0007286spermatid development1.00e-011.00e+003.2501144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.00e-011.00e+003.2501244
GO:0050434positive regulation of viral transcription1.00e-011.00e+003.2501544
GO:0015030Cajal body1.02e-011.00e+003.2171245
GO:0043966histone H3 acetylation1.02e-011.00e+003.2171245
GO:0021762substantia nigra development1.04e-011.00e+003.1851146
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.06e-011.00e+003.1541347
GO:0019003GDP binding1.09e-011.00e+003.1241248
GO:0045893positive regulation of transcription, DNA-templated1.10e-011.00e+001.366317487
GO:0003743translation initiation factor activity1.11e-011.00e+003.0941449
GO:0042802identical protein binding1.12e-011.00e+001.354318491
GO:0044822poly(A) RNA binding1.12e-011.00e+000.9575501078
GO:0035690cellular response to drug1.13e-011.00e+003.0651250
GO:0060326cell chemotaxis1.15e-011.00e+003.0371151
GO:0008168methyltransferase activity1.17e-011.00e+003.0091152
GO:0060041retina development in camera-type eye1.19e-011.00e+002.9811353
GO:0090305nucleic acid phosphodiester bond hydrolysis1.21e-011.00e+002.9541254
GO:0000226microtubule cytoskeleton organization1.23e-011.00e+002.9281355
GO:0000932cytoplasmic mRNA processing body1.26e-011.00e+002.9021356
GO:0071300cellular response to retinoic acid1.26e-011.00e+002.9021256
GO:0030097hemopoiesis1.30e-011.00e+002.8511358
GO:0008237metallopeptidase activity1.30e-011.00e+002.8511158
GO:0005840ribosome1.32e-011.00e+002.8261259
GO:0045216cell-cell junction organization1.32e-011.00e+002.8261259
GO:0005643nuclear pore1.32e-011.00e+002.8261459
GO:0010976positive regulation of neuron projection development1.34e-011.00e+002.8021160
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway1.36e-011.00e+002.7781261
GO:0019903protein phosphatase binding1.40e-011.00e+002.7321463
GO:0042995cell projection1.40e-011.00e+002.7321663
GO:0001558regulation of cell growth1.46e-011.00e+002.6651466
GO:0006368transcription elongation from RNA polymerase II promoter1.48e-011.00e+002.6431667
GO:0006338chromatin remodeling1.50e-011.00e+002.6221468
GO:0019899enzyme binding1.51e-011.00e+001.539211288
GO:0034329cell junction assembly1.57e-011.00e+002.5591171
GO:0000165MAPK cascade1.59e-011.00e+002.5391272
GO:0032355response to estradiol1.61e-011.00e+002.5191573
GO:0000785chromatin1.61e-011.00e+002.5191573
GO:0055086nucleobase-containing small molecule metabolic process1.61e-011.00e+002.5191573
GO:0006767water-soluble vitamin metabolic process1.65e-011.00e+002.4801375
GO:0007265Ras protein signal transduction1.65e-011.00e+002.4801375
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.67e-011.00e+002.4611376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.69e-011.00e+002.4421577
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.69e-011.00e+002.4421677
GO:0007229integrin-mediated signaling pathway1.71e-011.00e+002.4241278
GO:0006766vitamin metabolic process1.71e-011.00e+002.4241378
GO:0006334nucleosome assembly1.73e-011.00e+002.4051479
GO:0004725protein tyrosine phosphatase activity1.75e-011.00e+002.3871280
GO:0007565female pregnancy1.75e-011.00e+002.3871280
GO:0019083viral transcription1.77e-011.00e+002.3691881
GO:0051301cell division1.77e-011.00e+002.3691681
GO:0001889liver development1.79e-011.00e+002.3511382
GO:0001726ruffle1.79e-011.00e+002.3511482
GO:0004713protein tyrosine kinase activity1.79e-011.00e+002.3511282
GO:0045087innate immune response1.81e-011.00e+001.027320616
GO:0047485protein N-terminus binding1.86e-011.00e+002.2831486
GO:0006415translational termination1.88e-011.00e+002.2661887
GO:0050852T cell receptor signaling pathway1.90e-011.00e+002.2501288
GO:0003682chromatin binding1.90e-011.00e+001.325212334
GO:0003690double-stranded DNA binding1.96e-011.00e+002.2011491
GO:0042470melanosome1.98e-011.00e+002.18511092
GO:0006928cellular component movement1.98e-011.00e+002.1851792
GO:0006414translational elongation2.00e-011.00e+002.17011193
GO:0035335peptidyl-tyrosine dephosphorylation2.02e-011.00e+002.1541294
GO:0051082unfolded protein binding2.04e-011.00e+002.1391695
GO:0001649osteoblast differentiation2.04e-011.00e+002.1391695
GO:0006364rRNA processing2.06e-011.00e+002.1241596
GO:0003723RNA binding2.08e-011.00e+001.237219355
GO:0071456cellular response to hypoxia2.10e-011.00e+002.0941498
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.21e-011.00e+002.00918104
GO:0007156homophilic cell adhesion via plasma membrane adhesion molecules2.21e-011.00e+002.00911104
GO:0043235receptor complex2.21e-011.00e+002.00912104
GO:0005925focal adhesion2.21e-011.00e+001.178218370
GO:0014069postsynaptic density2.25e-011.00e+001.98111106
GO:0005815microtubule organizing center2.32e-011.00e+001.92814110
GO:0015630microtubule cytoskeleton2.36e-011.00e+001.90215112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.39e-011.00e+001.876110114
GO:0005819spindle2.39e-011.00e+001.87617114
GO:0017124SH3 domain binding2.41e-011.00e+001.86413115
GO:0005635nuclear envelope2.43e-011.00e+001.85116116
GO:0072562blood microparticle2.43e-011.00e+001.85114116
GO:0007219Notch signaling pathway2.59e-011.00e+001.74314125
GO:0008201heparin binding2.63e-011.00e+001.72012127
GO:0030027lamellipodium2.68e-011.00e+001.68714130
GO:0009615response to virus2.72e-011.00e+001.66516132
GO:0018108peptidyl-tyrosine phosphorylation2.73e-011.00e+001.65413133
GO:0003735structural constituent of ribosome2.87e-011.00e+001.56918141
GO:0007507heart development2.87e-011.00e+001.56915141
GO:0008286insulin receptor signaling pathway2.93e-011.00e+001.53916144
GO:0061024membrane organization2.96e-011.00e+001.51915146
GO:0007596blood coagulation3.05e-011.00e+000.851214464
GO:0010008endosome membrane3.14e-011.00e+001.41416157
GO:0046777protein autophosphorylation3.16e-011.00e+001.40513158
GO:0045121membrane raft3.21e-011.00e+001.37818161
GO:0044267cellular protein metabolic process3.32e-011.00e+000.758224495
GO:0006397mRNA processing3.34e-011.00e+001.30813169
GO:0030424axon3.39e-011.00e+001.28313172
GO:0016607nuclear speck3.44e-011.00e+001.25814175
GO:0004672protein kinase activity3.48e-011.00e+001.23312178
GO:0019904protein domain specific binding3.53e-011.00e+001.20916181
GO:0006367transcription initiation from RNA polymerase II promoter3.58e-011.00e+001.18518184
GO:0007173epidermal growth factor receptor signaling pathway3.68e-011.00e+001.13214191
GO:0004872receptor activity3.81e-011.00e+001.07213199
GO:0030168platelet activation3.90e-011.00e+001.03019205
GO:0001701in utero embryonic development3.97e-011.00e+000.99516210
GO:0004871signal transducer activity4.06e-011.00e+000.95414216
GO:0005622intracellular4.20e-011.00e+000.88915226
GO:0006412translation4.32e-011.00e+000.833115235
GO:0003713transcription coactivator activity4.38e-011.00e+000.808110239
GO:0043025neuronal cell body4.58e-011.00e+000.72014254
GO:0005739mitochondrion4.60e-011.00e+000.2633241046
GO:0004842ubiquitin-protein transferase activity4.61e-011.00e+000.70914256
GO:0005794Golgi apparatus4.64e-011.00e+000.365214650
GO:0046872metal ion binding4.69e-011.00e+000.1924241465
GO:0000166nucleotide binding4.81e-011.00e+000.62216272
GO:0048011neurotrophin TRK receptor signaling pathway4.82e-011.00e+000.61616273
GO:0006357regulation of transcription from RNA polymerase II promoter4.85e-011.00e+000.60616275
GO:0007283spermatogenesis4.86e-011.00e+000.60116276
GO:0042493response to drug5.01e-011.00e+000.539111288
GO:0007264small GTPase mediated signal transduction5.03e-011.00e+000.52913290
GO:0016567protein ubiquitination5.14e-011.00e+000.48515299
GO:0005856cytoskeleton5.28e-011.00e+000.42818311
GO:0007411axon guidance5.46e-011.00e+000.35619327
GO:0043231intracellular membrane-bounded organelle5.52e-011.00e+000.33418332
GO:0043565sequence-specific DNA binding5.87e-011.00e+000.19714365
GO:0007186G-protein coupled receptor signaling pathway5.89e-011.00e+000.18915367
GO:0008284positive regulation of cell proliferation6.13e-011.00e+000.09418392
GO:0046982protein heterodimerization activity6.20e-011.00e+000.069111399
GO:0006508proteolysis6.30e-011.00e+000.03019410
GO:0006366transcription from RNA polymerase II promoter6.43e-011.00e+00-0.022112425
GO:0007165signal transduction6.71e-011.00e+00-0.183217950
GO:0006468protein phosphorylation6.78e-011.00e+00-0.158110467
GO:0005887integral component of plasma membrane6.78e-011.00e+00-0.19927961
GO:0055114oxidation-reduction process6.89e-011.00e+00-0.201111481
GO:0008270zinc ion binding7.33e-011.00e+00-0.3502121067
GO:0005509calcium ion binding7.62e-011.00e+00-0.49318589
GO:0042803protein homodimerization activity7.78e-011.00e+00-0.560111617
GO:0005789endoplasmic reticulum membrane7.88e-011.00e+00-0.604110636
GO:0045944positive regulation of transcription from RNA polymerase II promoter8.63e-011.00e+00-0.955119811
GO:0006351transcription, DNA-templated9.04e-011.00e+00-0.9212251585
GO:0005615extracellular space9.17e-011.00e+00-1.2711171010
GO:0006355regulation of transcription, DNA-templated9.35e-011.00e+00-1.3991171104
GO:0003677DNA binding9.66e-011.00e+00-1.6911261351
GO:0005886plasma membrane9.95e-011.00e+00-1.7602382834