Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.953 | 3.19e-16 | 1.66e-03 | 3.00e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
[ PTPRF ] | 5792 | 1 | -0.344 | 0.953 | 28 | - | - |
CDC16 | 8881 | 25 | 0.950 | 1.020 | 80 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
RET | 5979 | 1 | -0.714 | 0.953 | 40 | - | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
BCAR1 | 9564 | 2 | -0.454 | 0.953 | 81 | - | Yes |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PTPRF | 5792 | RET | 5979 | pp | -- | int.I2D: BioGrid |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | CDC16 | 8881 | pp | -- | int.I2D: YeastLow |
PTPRF | 5792 | BCAR1 | 9564 | pp | -- | int.I2D: HPRD; int.HPRD: in vivo |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | BCAR1 | 9564 | pp | -- | int.I2D: MINT |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.23e-09 | 1.77e-05 | 6.531 | 5 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.80e-09 | 2.59e-05 | 6.424 | 5 | 22 | 70 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.39e-09 | 3.44e-05 | 6.344 | 5 | 22 | 74 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.33e-09 | 4.81e-05 | 6.249 | 5 | 23 | 79 |
GO:0006521 | regulation of cellular amino acid metabolic process | 6.20e-08 | 8.94e-04 | 6.587 | 4 | 17 | 50 |
GO:0000082 | G1/S transition of mitotic cell cycle | 8.22e-08 | 1.19e-03 | 5.334 | 5 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 8.50e-08 | 1.23e-03 | 5.324 | 5 | 24 | 150 |
GO:0000502 | proteasome complex | 1.14e-07 | 1.64e-03 | 6.373 | 4 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.70e-07 | 2.45e-03 | 6.231 | 4 | 19 | 64 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 2.74e-07 | 3.95e-03 | 6.061 | 4 | 20 | 72 |
GO:0000278 | mitotic cell cycle | 3.07e-07 | 4.44e-03 | 4.205 | 6 | 48 | 391 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 3.23e-07 | 4.67e-03 | 6.002 | 4 | 20 | 75 |
GO:0005654 | nucleoplasm | 3.69e-07 | 5.32e-03 | 3.152 | 8 | 76 | 1082 |
GO:0016071 | mRNA metabolic process | 6.13e-07 | 8.84e-03 | 4.752 | 5 | 31 | 223 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 7.38e-07 | 1.06e-02 | 5.708 | 4 | 21 | 92 |
GO:0016070 | RNA metabolic process | 1.02e-06 | 1.46e-02 | 4.605 | 5 | 32 | 247 |
GO:0000209 | protein polyubiquitination | 1.87e-06 | 2.70e-02 | 5.373 | 4 | 20 | 116 |
GO:0016032 | viral process | 1.91e-06 | 2.76e-02 | 3.755 | 6 | 55 | 534 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.77e-06 | 1.26e-01 | 4.813 | 4 | 20 | 171 |
GO:0005829 | cytosol | 1.83e-05 | 2.63e-01 | 2.116 | 9 | 132 | 2496 |
GO:0005838 | proteasome regulatory particle | 4.17e-05 | 6.01e-01 | 7.646 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 8.57e-05 | 1.00e+00 | 7.144 | 2 | 8 | 17 |
GO:0005839 | proteasome core complex | 9.64e-05 | 1.00e+00 | 7.061 | 2 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 1.08e-04 | 1.00e+00 | 6.983 | 2 | 8 | 19 |
GO:0010467 | gene expression | 1.28e-04 | 1.00e+00 | 3.167 | 5 | 59 | 669 |
GO:0043066 | negative regulation of apoptotic process | 3.02e-04 | 1.00e+00 | 3.503 | 4 | 31 | 424 |
GO:0006915 | apoptotic process | 8.39e-04 | 1.00e+00 | 3.115 | 4 | 33 | 555 |
GO:0070062 | extracellular vesicular exosome | 1.27e-03 | 1.00e+00 | 1.810 | 7 | 104 | 2400 |
GO:0097021 | lymphocyte migration into lymphoid organs | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0007497 | posterior midgut development | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0001838 | embryonic epithelial tube formation | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:1900121 | negative regulation of receptor binding | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0061146 | Peyer's patch morphogenesis | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0014042 | positive regulation of neuron maturation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0072300 | positive regulation of metanephric glomerulus development | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0007155 | cell adhesion | 3.08e-03 | 1.00e+00 | 3.289 | 3 | 6 | 369 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0035799 | ureter maturation | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0005515 | protein binding | 4.10e-03 | 1.00e+00 | 0.997 | 10 | 184 | 6024 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 2 | 5 |
GO:0033619 | membrane protein proteolysis | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0050851 | antigen receptor-mediated signaling pathway | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0000730 | DNA recombinase assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0030335 | positive regulation of cell migration | 4.79e-03 | 1.00e+00 | 4.242 | 2 | 7 | 127 |
GO:0016477 | cell migration | 4.87e-03 | 1.00e+00 | 4.231 | 2 | 5 | 128 |
GO:0048012 | hepatocyte growth factor receptor signaling pathway | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0000028 | ribosomal small subunit assembly | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0035729 | cellular response to hepatocyte growth factor stimulus | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 7 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 4 | 8 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0045793 | positive regulation of cell size | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0005730 | nucleolus | 7.54e-03 | 1.00e+00 | 1.873 | 5 | 69 | 1641 |
GO:0048484 | enteric nervous system development | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0042551 | neuron maturation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 4 | 11 |
GO:0033630 | positive regulation of cell adhesion mediated by integrin | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0031625 | ubiquitin protein ligase binding | 9.22e-03 | 1.00e+00 | 3.755 | 2 | 14 | 178 |
GO:0032403 | protein complex binding | 9.72e-03 | 1.00e+00 | 3.715 | 2 | 10 | 183 |
GO:0060384 | innervation | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 12 |
GO:0005662 | DNA replication factor A complex | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0007158 | neuron cell-cell adhesion | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 3 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 4 | 14 |
GO:0048265 | response to pain | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 14 |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 3 | 16 |
GO:0044281 | small molecule metabolic process | 1.42e-02 | 1.00e+00 | 1.989 | 4 | 58 | 1211 |
GO:0007088 | regulation of mitosis | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0035861 | site of double-strand break | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0048010 | vascular endothelial growth factor receptor signaling pathway | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 20 |
GO:0005680 | anaphase-promoting complex | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 4 | 20 |
GO:0006298 | mismatch repair | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 20 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 5 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0005844 | polysome | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0006281 | DNA repair | 1.91e-02 | 1.00e+00 | 3.203 | 2 | 18 | 261 |
GO:0000722 | telomere maintenance via recombination | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 5 | 25 |
GO:0070979 | protein K11-linked ubiquitination | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 6 | 26 |
GO:0050770 | regulation of axonogenesis | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 3 | 26 |
GO:0048008 | platelet-derived growth factor receptor signaling pathway | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 27 |
GO:0043022 | ribosome binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 27 |
GO:0001755 | neural crest cell migration | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 28 |
GO:0019894 | kinesin binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 1 | 29 |
GO:0050853 | B cell receptor signaling pathway | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 1 | 29 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 7 | 30 |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 2 | 30 |
GO:0007094 | mitotic spindle assembly checkpoint | 2.55e-02 | 1.00e+00 | 5.277 | 1 | 4 | 31 |
GO:0019901 | protein kinase binding | 2.75e-02 | 1.00e+00 | 2.923 | 2 | 21 | 317 |
GO:0001895 | retina homeostasis | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 |
GO:0005876 | spindle microtubule | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0005813 | centrosome | 2.89e-02 | 1.00e+00 | 2.882 | 2 | 14 | 326 |
GO:0008283 | cell proliferation | 2.93e-02 | 1.00e+00 | 2.874 | 2 | 14 | 328 |
GO:0034332 | adherens junction organization | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 4 | 37 |
GO:0007015 | actin filament organization | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 2 | 37 |
GO:0006284 | base-excision repair | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 3 | 37 |
GO:0001657 | ureteric bud development | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 38 |
GO:0070527 | platelet aggregation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0010595 | positive regulation of endothelial cell migration | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 39 |
GO:0000781 | chromosome, telomeric region | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 3 | 39 |
GO:0030155 | regulation of cell adhesion | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 2 | 42 |
GO:0005925 | focal adhesion | 3.58e-02 | 1.00e+00 | 2.715 | 2 | 19 | 366 |
GO:0021762 | substantia nigra development | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.76e-02 | 1.00e+00 | 4.708 | 1 | 7 | 46 |
GO:0003684 | damaged DNA binding | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 7 | 49 |
GO:0060326 | cell chemotaxis | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 50 |
GO:0060041 | retina development in camera-type eye | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 2 | 51 |
GO:0016020 | membrane | 4.22e-02 | 1.00e+00 | 1.516 | 4 | 90 | 1681 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 54 |
GO:0071300 | cellular response to retinoic acid | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 2 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 6 | 56 |
GO:0010976 | positive regulation of neuron projection development | 4.72e-02 | 1.00e+00 | 4.373 | 1 | 1 | 58 |
GO:0001558 | regulation of cell growth | 4.96e-02 | 1.00e+00 | 4.300 | 1 | 2 | 61 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 4.96e-02 | 1.00e+00 | 4.300 | 1 | 2 | 61 |
GO:0019903 | protein phosphatase binding | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0007596 | blood coagulation | 5.32e-02 | 1.00e+00 | 2.401 | 2 | 18 | 455 |
GO:0006289 | nucleotide-excision repair | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 11 | 68 |
GO:0034329 | cell junction assembly | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 5 | 68 |
GO:0044267 | cellular protein metabolic process | 5.72e-02 | 1.00e+00 | 2.342 | 2 | 29 | 474 |
GO:0000165 | MAPK cascade | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 2 | 72 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 2 | 75 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 6.22e-02 | 1.00e+00 | 3.964 | 1 | 7 | 77 |
GO:0004725 | protein tyrosine phosphatase activity | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 1 | 78 |
GO:0007229 | integrin-mediated signaling pathway | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 2 | 78 |
GO:0001726 | ruffle | 6.46e-02 | 1.00e+00 | 3.909 | 1 | 4 | 80 |
GO:0051301 | cell division | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 5 | 81 |
GO:0019083 | viral transcription | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 10 | 81 |
GO:0004713 | protein tyrosine kinase activity | 6.62e-02 | 1.00e+00 | 3.874 | 1 | 5 | 82 |
GO:0050852 | T cell receptor signaling pathway | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 4 | 85 |
GO:0047485 | protein N-terminus binding | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 5 | 86 |
GO:0006415 | translational termination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 10 | 87 |
GO:0016605 | PML body | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 3 | 88 |
GO:0006928 | cellular component movement | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 7 | 91 |
GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 1 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 8 | 91 |
GO:0071456 | cellular response to hypoxia | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 6 | 92 |
GO:0035335 | peptidyl-tyrosine dephosphorylation | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 1 | 92 |
GO:0006414 | translational elongation | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 13 | 93 |
GO:0043235 | receptor complex | 7.94e-02 | 1.00e+00 | 3.602 | 1 | 2 | 99 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 8.40e-02 | 1.00e+00 | 3.517 | 1 | 3 | 105 |
GO:0015630 | microtubule cytoskeleton | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 8.86e-02 | 1.00e+00 | 3.437 | 1 | 3 | 111 |
GO:0030529 | ribonucleoprotein complex | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 8 | 112 |
GO:0005819 | spindle | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 7 | 112 |
GO:0017124 | SH3 domain binding | 9.01e-02 | 1.00e+00 | 3.411 | 1 | 3 | 113 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.09e-02 | 1.00e+00 | 3.398 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 13 | 115 |
GO:0006325 | chromatin organization | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 9.54e-02 | 1.00e+00 | 3.324 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 9.62e-02 | 1.00e+00 | 3.312 | 1 | 9 | 121 |
GO:0008201 | heparin binding | 9.69e-02 | 1.00e+00 | 3.300 | 1 | 4 | 122 |
GO:0030027 | lamellipodium | 9.92e-02 | 1.00e+00 | 3.265 | 1 | 4 | 125 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 9 | 129 |
GO:0006413 | translational initiation | 1.04e-01 | 1.00e+00 | 3.198 | 1 | 17 | 131 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 1.04e-01 | 1.00e+00 | 3.187 | 1 | 7 | 132 |
GO:0003735 | structural constituent of ribosome | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 10 | 137 |
GO:0008286 | insulin receptor signaling pathway | 1.12e-01 | 1.00e+00 | 3.081 | 1 | 7 | 142 |
GO:0006457 | protein folding | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.14e-01 | 1.00e+00 | 3.051 | 1 | 7 | 145 |
GO:0010008 | endosome membrane | 1.19e-01 | 1.00e+00 | 2.993 | 1 | 7 | 151 |
GO:0045121 | membrane raft | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 8 | 156 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 7 | 165 |
GO:0030424 | axon | 1.30e-01 | 1.00e+00 | 2.856 | 1 | 4 | 166 |
GO:0005634 | nucleus | 1.45e-01 | 1.00e+00 | 0.662 | 6 | 136 | 4559 |
GO:0004872 | receptor activity | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 2 | 189 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 12 | 189 |
GO:0030168 | platelet activation | 1.58e-01 | 1.00e+00 | 2.552 | 1 | 10 | 205 |
GO:0004871 | signal transducer activity | 1.60e-01 | 1.00e+00 | 2.531 | 1 | 4 | 208 |
GO:0005887 | integral component of plasma membrane | 1.66e-01 | 1.00e+00 | 1.437 | 2 | 6 | 888 |
GO:0007067 | mitotic nuclear division | 1.73e-01 | 1.00e+00 | 2.405 | 1 | 14 | 227 |
GO:0006412 | translation | 1.75e-01 | 1.00e+00 | 2.386 | 1 | 20 | 230 |
GO:0005737 | cytoplasm | 1.81e-01 | 1.00e+00 | 0.674 | 5 | 110 | 3767 |
GO:0004842 | ubiquitin-protein transferase activity | 1.93e-01 | 1.00e+00 | 2.237 | 1 | 6 | 255 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 2.02e-01 | 1.00e+00 | 2.160 | 1 | 15 | 269 |
GO:0019899 | enzyme binding | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 12 | 277 |
GO:0042493 | response to drug | 2.12e-01 | 1.00e+00 | 2.081 | 1 | 13 | 284 |
GO:0007186 | G-protein coupled receptor signaling pathway | 2.16e-01 | 1.00e+00 | 2.056 | 1 | 7 | 289 |
GO:0005856 | cytoskeleton | 2.17e-01 | 1.00e+00 | 2.046 | 1 | 12 | 291 |
GO:0043234 | protein complex | 2.20e-01 | 1.00e+00 | 2.027 | 1 | 18 | 295 |
GO:0016567 | protein ubiquitination | 2.20e-01 | 1.00e+00 | 2.027 | 1 | 5 | 295 |
GO:0007411 | axon guidance | 2.35e-01 | 1.00e+00 | 1.914 | 1 | 13 | 319 |
GO:0003723 | RNA binding | 2.50e-01 | 1.00e+00 | 1.813 | 1 | 20 | 342 |
GO:0005524 | ATP binding | 2.95e-01 | 1.00e+00 | 0.889 | 2 | 60 | 1298 |
GO:0006468 | protein phosphorylation | 3.22e-01 | 1.00e+00 | 1.386 | 1 | 18 | 460 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.33e-01 | 1.00e+00 | 1.330 | 1 | 13 | 478 |
GO:0005509 | calcium ion binding | 3.63e-01 | 1.00e+00 | 1.179 | 1 | 5 | 531 |
GO:0045087 | innate immune response | 3.97e-01 | 1.00e+00 | 1.012 | 1 | 24 | 596 |
GO:0007165 | signal transduction | 5.41e-01 | 1.00e+00 | 0.406 | 1 | 24 | 907 |
GO:0005615 | extracellular space | 5.61e-01 | 1.00e+00 | 0.329 | 1 | 17 | 957 |
GO:0008270 | zinc ion binding | 5.77e-01 | 1.00e+00 | 0.270 | 1 | 12 | 997 |
GO:0044822 | poly(A) RNA binding | 5.99e-01 | 1.00e+00 | 0.187 | 1 | 49 | 1056 |
GO:0005886 | plasma membrane | 6.61e-01 | 1.00e+00 | -0.103 | 2 | 45 | 2582 |