meta-int-snw-55143

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-11277	wolf-screen-ratio-mammosphere-adherent	0.882	1.09e-07	9.11e-04	1.96e-03	10	9
int-snw-55143	wolf-screen-ratio-mammosphere-adherent	0.934	1.73e-15	2.51e-03	4.05e-02	13	10
reg-snw-4522	wolf-screen-ratio-mammosphere-adherent	0.815	1.50e-06	3.75e-03	6.95e-03	14	12
reg-snw-56655	wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03	8	7
reg-snw-317781	wolf-screen-ratio-mammosphere-adherent	0.823	1.13e-06	3.23e-03	6.07e-03	9	9
reg-snw-1434	wolf-screen-ratio-mammosphere-adherent	0.865	2.23e-07	1.35e-03	2.78e-03	9	7
reg-snw-6723	wolf-screen-ratio-mammosphere-adherent	0.840	5.77e-07	2.25e-03	4.41e-03	13	11
reg-snw-6418	wolf-screen-ratio-mammosphere-adherent	0.858	2.92e-07	1.56e-03	3.18e-03	8	6

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-55143 subnetwork

Genes (38)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
SRM	6723	13	-0.064	0.840	32	-	-
PSMB1	5689	61	0.688	0.901	113	Yes	-
PSMA2	5683	112	1.093	1.106	108	Yes	-
PHB2	11331	43	0.829	0.956	151	Yes	-
POLR2F	5435	62	0.891	0.956	26	Yes	-
SUMO2	6613	11	-0.466	0.983	199	-	-
CDCA8	55143	8	0.317	0.934	16	-	-
RRM1	6240	15	0.587	0.872	117	Yes	-
CSE1L	1434	41	0.304	0.865	54	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
DDX51	317781	53	0.059	0.823	210	Yes	-
CAD	790	91	0.807	0.973	400	-	-
EIF6	3692	67	0.700	0.876	316	Yes	-
CCNA2	890	54	0.550	0.973	246	Yes	-
EFTUD2	9343	93	0.883	0.956	108	Yes	-
TUBG1	7283	98	0.974	0.973	91	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
RAN	5901	89	0.632	0.899	258	Yes	-
FBL	2091	42	0.839	0.956	79	Yes	-
PRMT3	10196	49	0.431	0.815	26	-	-
MTHFD1	4522	49	0.194	0.815	26	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
PSMA1	5682	100	0.996	0.878	152	Yes	-
TREX1	11277	51	-0.051	0.882	91	Yes	-
POLE4	56655	63	0.177	0.828	56	-	-
PSMB3	5691	64	0.668	0.901	19	Yes	-
RPSA	3921	120	1.327	1.151	152	Yes	-
RPA1	6117	51	0.425	0.865	74	-	-
PGD	5226	89	1.201	1.106	152	Yes	-
ACO2	50	65	1.000	1.076	191	Yes	-
RUVBL1	8607	95	0.720	0.973	469	Yes	-
PSMD3	5709	100	0.986	1.106	201	Yes	-
SET	6418	6	0.317	0.858	30	-	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
RUVBL2	10856	95	0.693	0.956	532	Yes	-

Interactions (149)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACO2	50	RPA1	6117	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
RUVBL2	10856	CDCA8	55143	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	RUVBL1	8607	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMB1	5689	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
CSE1L	1434	RAN	5901	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG; int.HPRD: in vitro
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pp	--	int.I2D: BioGrid
CAD	790	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	TREX1	11277	pd	<	reg.ITFP.txt: no annot
ACTB	60	RUVBL1	8607	pp	--	int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PGD	5226	RAN	5901	pp	--	int.I2D: YeastLow
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
RPA1	6117	RUVBL1	8607	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1	6117	VARS	7407	pp	--	int.I2D: YeastLow
CAD	790	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RAN	5901	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
PSMB1	5689	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
RUVBL1	8607	CDCA8	55143	pd	>	reg.ITFP.txt: no annot
PSMB3	5691	PSMD3	5709	pp	--	int.I2D: YeastLow
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPA1	6117	TREX1	11277	pp	--	int.I2D: BCI; int.HPRD: in vitro
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
CCNA2	890	CSE1L	1434	pd	>	reg.ITFP.txt: no annot
RPA1	6117	RUVBL2	10856	pp	--	int.I2D: YeastLow
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMB1	5689	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast; int.Mint: MI:0915(physical association)
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
TREX1	11277	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
PSMA1	5682	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
SRM	6723	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
RPSA	3921	VARS	7407	pp	--	int.I2D: IntAct_Yeast
EIF6	3692	RRM1	6240	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
EIF6	3692	PGD	5226	pp	--	int.I2D: YeastLow
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
CSE1L	1434	RPA1	6117	pd	<	reg.ITFP.txt: no annot
SRM	6723	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
SET	6418	TREX1	11277	pp	--	int.I2D: BioGrid, INNATEDB
CCNA2	890	RRM1	6240	pd	>	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd; int.Ravasi: -; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
RPSA	3921	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
FBL	2091	PRMT3	10196	pp	--	int.I2D: BioGrid
ACO2	50	EIF6	3692	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1	4522	PRMT3	10196	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	SUMO2	6613	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	CAD	790	pp	--	int.I2D: IntAct_Yeast
CCNA2	890	SET	6418	pd	>	reg.ITFP.txt: no annot
PSMA1	5682	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	RUVBL2	10856	pp	--	int.I2D: YeastLow
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
CAD	790	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
ACTB	60	SET	6418	pp	--	int.I2D: IntAct_Worm, BioGrid_Mouse, BioGrid_Worm, BIND_Worm, MINT_Worm
CSE1L	1434	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
ACTB	60	FBL	2091	pp	--	int.I2D: MINT
PSMB1	5689	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
RPA1	6117	RRM1	6240	pd	>	reg.ITFP.txt: no annot
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMB7	5695	DDX51	317781	pd	<	reg.ITFP.txt: no annot
SRM	6723	VARS	7407	pd	<	reg.ITFP.txt: no annot
SRM	6723	VARS	7407	pp	--	int.I2D: YeastLow
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	VARS	7407	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
EIF6	3692	SRM	6723	pp	--	int.I2D: YeastLow
SUMO2	6613	RUVBL1	8607	pp	--	int.I2D: BioGrid
FBL	2091	RUVBL1	8607	pp	--	int.I2D: BioGrid
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
SUMO2	6613	CDCA8	55143	pp	--	int.I2D: BioGrid
RAN	5901	VARS	7407	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
CAD	790	RAN	5901	pp	--	int.I2D: IntAct_Yeast
PSMB3	5691	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1	4522	RPA1	6117	pd	<	reg.ITFP.txt: no annot
VARS	7407	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMB7	5695	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
RPSA	3921	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
PSMB1	5689	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
CAD	790	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	DDX51	317781	pd	<	reg.ITFP.txt: no annot
CCNA2	890	CDCA8	55143	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
PSMD11	5717	RUVBL2	10856	pp	--	int.I2D: YeastLow
FBL	2091	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
FBL	2091	RUVBL2	10856	pp	--	int.I2D: BioGrid
CAD	790	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
PSMB1	5689	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
ACO2	50	RUVBL1	8607	pp	--	int.I2D: YeastLow
PSMB1	5689	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	CSE1L	1434	pp	--	int.I2D: IntAct_Yeast
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
SRM	6723	DDX51	317781	pd	<	reg.ITFP.txt: no annot
EIF6	3692	PSMB1	5689	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMA2	5683	PSMB1	5689	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
ACTB	60	RPA1	6117	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMB3	5691	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMB7	5695	RPA1	6117	pd	<	reg.ITFP.txt: no annot
CAD	790	SUMO2	6613	pp	--	int.I2D: BioGrid
CCNA2	890	RPA1	6117	pp	--	int.I2D: BioGrid
EIF6	3692	DDX51	317781	pd	<	reg.ITFP.txt: no annot
EIF6	3692	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RAN	5901	TREX1	11277	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	RRM1	6240	pd	>	reg.ITFP.txt: no annot
RUVBL2	10856	TREX1	11277	pd	<>	reg.ITFP.txt: no annot
ACTB	60	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
TREX1	11277	CDCA8	55143	pd	>	reg.ITFP.txt: no annot
POLR2F	5435	VARS	7407	pd	<	reg.ITFP.txt: no annot
ACTB	60	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
RUVBL2	10856	PHB2	11331	pd	>	reg.ITFP.txt: no annot
RUVBL2	10856	PHB2	11331	pp	--	int.I2D: IntAct_Yeast
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6	3692	RUVBL1	8607	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct

Related GO terms (425)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.83e-15	2.98e-11	3.042	21	83	1095
GO:0000278	mitotic cell cycle	1.19e-13	1.94e-09	3.917	14	52	398
GO:0006521	regulation of cellular amino acid metabolic process	1.97e-13	3.21e-09	6.103	8	21	50
GO:0000502	proteasome complex	6.93e-13	1.13e-08	5.889	8	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.80e-12	2.94e-08	5.724	8	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.80e-12	2.94e-08	5.724	8	22	65
GO:0005839	proteasome core complex	1.92e-12	3.13e-08	7.162	6	11	18
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.35e-12	5.46e-08	5.617	8	24	70
GO:0004298	threonine-type endopeptidase activity	3.98e-12	6.50e-08	7.010	6	11	20
GO:0005829	cytosol	4.70e-12	7.67e-08	2.067	25	125	2562
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	4.74e-12	7.74e-08	5.557	8	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.31e-12	8.66e-08	5.537	8	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.37e-12	1.20e-07	5.480	8	23	77
GO:0010467	gene expression	8.54e-12	1.39e-07	3.268	15	58	669
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	9.11e-12	1.49e-07	5.443	8	25	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.79e-11	6.19e-07	5.192	8	23	94
GO:0000082	G1/S transition of mitotic cell cycle	4.77e-11	7.79e-07	4.688	9	33	150
GO:0016071	mRNA metabolic process	6.27e-11	1.02e-06	4.268	10	34	223
GO:0016070	RNA metabolic process	1.71e-10	2.79e-06	4.120	10	34	247
GO:0000209	protein polyubiquitination	2.09e-10	3.41e-06	4.889	8	21	116
GO:0034641	cellular nitrogen compound metabolic process	2.10e-10	3.44e-06	4.449	9	25	177
GO:0042981	regulation of apoptotic process	1.72e-09	2.81e-05	4.508	8	26	151
GO:0016032	viral process	1.88e-09	3.07e-05	3.255	12	55	540
GO:0070062	extracellular vesicular exosome	2.25e-09	3.67e-05	1.909	22	98	2516
GO:0005634	nucleus	3.46e-09	5.64e-05	1.367	29	131	4828
GO:0044281	small molecule metabolic process	7.74e-08	1.26e-03	2.315	15	57	1295
GO:0005730	nucleolus	3.74e-07	6.11e-03	2.029	16	70	1684
GO:0016020	membrane	3.66e-06	5.97e-02	1.884	15	80	1746
GO:0035267	NuA4 histone acetyltransferase complex	4.16e-06	6.80e-02	6.524	3	4	14
GO:0006915	apoptotic process	4.85e-06	7.91e-02	2.759	9	34	571
GO:0043066	negative regulation of apoptotic process	5.59e-06	9.13e-02	2.988	8	30	433
GO:0005515	protein binding	6.36e-06	1.04e-01	0.973	28	172	6127
GO:0006310	DNA recombination	1.72e-05	2.81e-01	4.680	4	4	67
GO:0006281	DNA repair	3.03e-05	4.94e-01	3.287	6	22	264
GO:0016363	nuclear matrix	6.03e-05	9.84e-01	4.223	4	11	92
GO:0043234	protein complex	6.17e-05	1.00e+00	3.103	6	17	300
GO:0000812	Swr1 complex	1.47e-04	1.00e+00	6.747	2	3	8
GO:0019773	proteasome core complex, alpha-subunit complex	1.47e-04	1.00e+00	6.747	2	5	8
GO:0006260	DNA replication	1.98e-04	1.00e+00	3.781	4	12	125
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.66e-04	1.00e+00	4.577	3	5	54
GO:0043968	histone H2A acetylation	3.43e-04	1.00e+00	6.162	2	3	12
GO:0005838	proteasome regulatory particle	3.43e-04	1.00e+00	6.162	2	7	12
GO:0031011	Ino80 complex	4.72e-04	1.00e+00	5.939	2	3	14
GO:0022624	proteasome accessory complex	7.02e-04	1.00e+00	5.659	2	9	17
GO:0006259	DNA metabolic process	8.80e-04	1.00e+00	5.499	2	3	19
GO:0003678	DNA helicase activity	8.80e-04	1.00e+00	5.499	2	3	19
GO:0006298	mismatch repair	9.77e-04	1.00e+00	5.425	2	6	20
GO:0043044	ATP-dependent chromatin remodeling	1.29e-03	1.00e+00	5.223	2	4	23
GO:0006206	pyrimidine nucleobase metabolic process	1.41e-03	1.00e+00	5.162	2	2	24
GO:0006611	protein export from nucleus	1.53e-03	1.00e+00	5.103	2	4	25
GO:0071339	MLL1 complex	1.79e-03	1.00e+00	4.992	2	3	27
GO:0043022	ribosome binding	1.92e-03	1.00e+00	4.939	2	3	28
GO:0043967	histone H4 acetylation	1.92e-03	1.00e+00	4.939	2	3	28
GO:0031492	nucleosomal DNA binding	1.92e-03	1.00e+00	4.939	2	4	28
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	2.33e-03	1.00e+00	8.747	1	1	1
GO:0070335	aspartate binding	2.33e-03	1.00e+00	8.747	1	1	1
GO:0008262	importin-alpha export receptor activity	2.33e-03	1.00e+00	8.747	1	1	1
GO:1990259	histone-glutamine methyltransferase activity	2.33e-03	1.00e+00	8.747	1	1	1
GO:0032558	adenyl deoxyribonucleotide binding	2.33e-03	1.00e+00	8.747	1	1	1
GO:1990258	histone glutamine methylation	2.33e-03	1.00e+00	8.747	1	1	1
GO:0004151	dihydroorotase activity	2.33e-03	1.00e+00	8.747	1	1	1
GO:0019521	D-gluconate metabolic process	2.33e-03	1.00e+00	8.747	1	1	1
GO:0000054	ribosomal subunit export from nucleus	2.33e-03	1.00e+00	8.747	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	2.33e-03	1.00e+00	8.747	1	1	1
GO:0016074	snoRNA metabolic process	2.33e-03	1.00e+00	8.747	1	1	1
GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	2.33e-03	1.00e+00	8.747	1	1	1
GO:0030529	ribonucleoprotein complex	2.34e-03	1.00e+00	3.499	3	8	114
GO:0006325	chromatin organization	2.91e-03	1.00e+00	3.389	3	4	123
GO:0032508	DNA duplex unwinding	4.29e-03	1.00e+00	4.354	2	4	42
GO:0004832	valine-tRNA ligase activity	4.65e-03	1.00e+00	7.747	1	1	2
GO:0051538	3 iron, 4 sulfur cluster binding	4.65e-03	1.00e+00	7.747	1	1	2
GO:0003994	aconitate hydratase activity	4.65e-03	1.00e+00	7.747	1	1	2
GO:0006407	rRNA export from nucleus	4.65e-03	1.00e+00	7.747	1	1	2
GO:0006438	valyl-tRNA aminoacylation	4.65e-03	1.00e+00	7.747	1	1	2
GO:0004766	spermidine synthase activity	4.65e-03	1.00e+00	7.747	1	1	2
GO:0000105	histidine biosynthetic process	4.65e-03	1.00e+00	7.747	1	1	2
GO:0008295	spermidine biosynthetic process	4.65e-03	1.00e+00	7.747	1	1	2
GO:0008296	3'-5'-exodeoxyribonuclease activity	4.65e-03	1.00e+00	7.747	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.65e-03	1.00e+00	7.747	1	1	2
GO:0019322	pentose biosynthetic process	4.65e-03	1.00e+00	7.747	1	1	2
GO:0005055	laminin receptor activity	4.65e-03	1.00e+00	7.747	1	1	2
GO:0070409	carbamoyl phosphate biosynthetic process	4.65e-03	1.00e+00	7.747	1	1	2
GO:0015030	Cajal body	4.91e-03	1.00e+00	4.255	2	2	45
GO:0006283	transcription-coupled nucleotide-excision repair	5.12e-03	1.00e+00	4.223	2	8	46
GO:0031100	organ regeneration	6.03e-03	1.00e+00	4.103	2	4	50
GO:0040008	regulation of growth	6.26e-03	1.00e+00	4.074	2	3	51
GO:0003684	damaged DNA binding	6.26e-03	1.00e+00	4.074	2	11	51
GO:0000398	mRNA splicing, via spliceosome	6.60e-03	1.00e+00	2.965	3	12	165
GO:0009263	deoxyribonucleotide biosynthetic process	6.97e-03	1.00e+00	7.162	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	6.97e-03	1.00e+00	7.162	1	1	3
GO:0071899	negative regulation of estrogen receptor binding	6.97e-03	1.00e+00	7.162	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	6.97e-03	1.00e+00	7.162	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	6.97e-03	1.00e+00	7.162	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	6.97e-03	1.00e+00	7.162	1	1	3
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	6.97e-03	1.00e+00	7.162	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	6.97e-03	1.00e+00	7.162	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	6.97e-03	1.00e+00	7.162	1	1	3
GO:0032481	positive regulation of type I interferon production	8.86e-03	1.00e+00	3.816	2	6	61
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.28e-03	1.00e+00	6.747	1	1	4
GO:0000212	meiotic spindle organization	9.28e-03	1.00e+00	6.747	1	1	4
GO:0030686	90S preribosome	9.28e-03	1.00e+00	6.747	1	1	4
GO:0019788	NEDD8 ligase activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0001652	granular component	9.28e-03	1.00e+00	6.747	1	1	4
GO:0016274	protein-arginine N-methyltransferase activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0031428	box C/D snoRNP complex	9.28e-03	1.00e+00	6.747	1	1	4
GO:0004329	formate-tetrahydrofolate ligase activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0034969	histone arginine methylation	9.28e-03	1.00e+00	6.747	1	1	4
GO:0006543	glutamine catabolic process	9.28e-03	1.00e+00	6.747	1	1	4
GO:0032133	chromosome passenger complex	9.28e-03	1.00e+00	6.747	1	1	4
GO:0009396	folic acid-containing compound biosynthetic process	9.28e-03	1.00e+00	6.747	1	1	4
GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	9.28e-03	1.00e+00	6.747	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	9.28e-03	1.00e+00	6.747	1	1	4
GO:0008853	exodeoxyribonuclease III activity	9.28e-03	1.00e+00	6.747	1	1	4
GO:0042995	cell projection	9.43e-03	1.00e+00	3.769	2	6	63
GO:0006289	nucleotide-excision repair	1.12e-02	1.00e+00	3.638	2	12	69
GO:0003697	single-stranded DNA binding	1.12e-02	1.00e+00	3.638	2	9	69
GO:0044822	poly(A) RNA binding	1.12e-02	1.00e+00	1.480	7	50	1078
GO:0005524	ATP binding	1.14e-02	1.00e+00	1.344	8	46	1354
GO:0051414	response to cortisol	1.16e-02	1.00e+00	6.425	1	1	5
GO:0003924	GTPase activity	1.16e-02	1.00e+00	2.666	3	9	203
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	1.16e-02	1.00e+00	6.425	1	2	5
GO:0042256	mature ribosome assembly	1.16e-02	1.00e+00	6.425	1	1	5
GO:0001940	male pronucleus	1.16e-02	1.00e+00	6.425	1	1	5
GO:0009086	methionine biosynthetic process	1.16e-02	1.00e+00	6.425	1	1	5
GO:0032407	MutSalpha complex binding	1.16e-02	1.00e+00	6.425	1	1	5
GO:0008622	epsilon DNA polymerase complex	1.16e-02	1.00e+00	6.425	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	1.16e-02	1.00e+00	6.425	1	1	5
GO:0071169	establishment of protein localization to chromatin	1.16e-02	1.00e+00	6.425	1	1	5
GO:0043248	proteasome assembly	1.16e-02	1.00e+00	6.425	1	1	5
GO:0006102	isocitrate metabolic process	1.16e-02	1.00e+00	6.425	1	1	5
GO:0030891	VCB complex	1.16e-02	1.00e+00	6.425	1	2	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	1.16e-02	1.00e+00	6.425	1	1	5
GO:0005827	polar microtubule	1.16e-02	1.00e+00	6.425	1	1	5
GO:0000730	DNA recombinase assembly	1.16e-02	1.00e+00	6.425	1	3	5
GO:0005638	lamin filament	1.16e-02	1.00e+00	6.425	1	1	5
GO:0005737	cytoplasm	1.20e-02	1.00e+00	0.789	16	98	3976
GO:0055086	nucleobase-containing small molecule metabolic process	1.25e-02	1.00e+00	3.557	2	5	73
GO:0060744	mammary gland branching involved in thelarche	1.39e-02	1.00e+00	6.162	1	1	6
GO:0006101	citrate metabolic process	1.39e-02	1.00e+00	6.162	1	1	6
GO:0043023	ribosomal large subunit binding	1.39e-02	1.00e+00	6.162	1	2	6
GO:0031466	Cul5-RING ubiquitin ligase complex	1.39e-02	1.00e+00	6.162	1	1	6
GO:0030957	Tat protein binding	1.39e-02	1.00e+00	6.162	1	4	6
GO:0046134	pyrimidine nucleoside biosynthetic process	1.39e-02	1.00e+00	6.162	1	1	6
GO:0032405	MutLalpha complex binding	1.39e-02	1.00e+00	6.162	1	2	6
GO:0008469	histone-arginine N-methyltransferase activity	1.39e-02	1.00e+00	6.162	1	1	6
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	1.39e-02	1.00e+00	6.162	1	1	6
GO:0006184	GTP catabolic process	1.44e-02	1.00e+00	2.550	3	9	220
GO:0006334	nucleosome assembly	1.45e-02	1.00e+00	3.443	2	4	79
GO:0071013	catalytic step 2 spliceosome	1.45e-02	1.00e+00	3.443	2	7	79
GO:0005681	spliceosomal complex	1.60e-02	1.00e+00	3.371	2	3	83
GO:0000028	ribosomal small subunit assembly	1.62e-02	1.00e+00	5.939	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	1.62e-02	1.00e+00	5.939	1	2	7
GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	1.62e-02	1.00e+00	5.939	1	1	7
GO:0001939	female pronucleus	1.62e-02	1.00e+00	5.939	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	1.62e-02	1.00e+00	5.939	1	2	7
GO:0035999	tetrahydrofolate interconversion	1.62e-02	1.00e+00	5.939	1	1	7
GO:0072341	modified amino acid binding	1.62e-02	1.00e+00	5.939	1	1	7
GO:0000930	gamma-tubulin complex	1.62e-02	1.00e+00	5.939	1	1	7
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.62e-02	1.00e+00	5.939	1	1	7
GO:0007067	mitotic nuclear division	1.64e-02	1.00e+00	2.480	3	13	231
GO:0008380	RNA splicing	1.66e-02	1.00e+00	2.473	3	13	232
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.85e-02	1.00e+00	5.747	1	2	8
GO:0001055	RNA polymerase II activity	1.85e-02	1.00e+00	5.747	1	3	8
GO:0035067	negative regulation of histone acetylation	1.85e-02	1.00e+00	5.747	1	1	8
GO:0070688	MLL5-L complex	1.85e-02	1.00e+00	5.747	1	1	8
GO:0045116	protein neddylation	1.85e-02	1.00e+00	5.747	1	2	8
GO:0000800	lateral element	1.85e-02	1.00e+00	5.747	1	1	8
GO:0006164	purine nucleotide biosynthetic process	1.85e-02	1.00e+00	5.747	1	2	8
GO:0016605	PML body	1.94e-02	1.00e+00	3.223	2	5	92
GO:0005200	structural constituent of cytoskeleton	1.98e-02	1.00e+00	3.207	2	7	93
GO:0001649	osteoblast differentiation	2.06e-02	1.00e+00	3.177	2	6	95
GO:0014075	response to amine	2.08e-02	1.00e+00	5.577	1	1	9
GO:0006228	UTP biosynthetic process	2.08e-02	1.00e+00	5.577	1	1	9
GO:0010389	regulation of G2/M transition of mitotic cell cycle	2.08e-02	1.00e+00	5.577	1	1	9
GO:0031000	response to caffeine	2.08e-02	1.00e+00	5.577	1	2	9
GO:0006364	rRNA processing	2.10e-02	1.00e+00	3.162	2	5	96
GO:0046655	folic acid metabolic process	2.30e-02	1.00e+00	5.425	1	1	10
GO:0006450	regulation of translational fidelity	2.30e-02	1.00e+00	5.425	1	2	10
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	2.30e-02	1.00e+00	5.425	1	1	10
GO:0006098	pentose-phosphate shunt	2.53e-02	1.00e+00	5.287	1	3	11
GO:0021846	cell proliferation in forebrain	2.53e-02	1.00e+00	5.287	1	1	11
GO:0010369	chromocenter	2.53e-02	1.00e+00	5.287	1	1	11
GO:0001054	RNA polymerase I activity	2.53e-02	1.00e+00	5.287	1	3	11
GO:0045120	pronucleus	2.53e-02	1.00e+00	5.287	1	1	11
GO:0019789	SUMO ligase activity	2.53e-02	1.00e+00	5.287	1	1	11
GO:0033762	response to glucagon	2.53e-02	1.00e+00	5.287	1	1	11
GO:0035458	cellular response to interferon-beta	2.53e-02	1.00e+00	5.287	1	2	11
GO:0051290	protein heterotetramerization	2.53e-02	1.00e+00	5.287	1	2	11
GO:0070935	3'-UTR-mediated mRNA stabilization	2.76e-02	1.00e+00	5.162	1	2	12
GO:0005736	DNA-directed RNA polymerase I complex	2.76e-02	1.00e+00	5.162	1	3	12
GO:0019058	viral life cycle	2.93e-02	1.00e+00	2.901	2	10	115
GO:0005635	nuclear envelope	2.98e-02	1.00e+00	2.889	2	6	116
GO:0042273	ribosomal large subunit biogenesis	2.99e-02	1.00e+00	5.046	1	4	13
GO:0007080	mitotic metaphase plate congression	2.99e-02	1.00e+00	5.046	1	1	13
GO:0032479	regulation of type I interferon production	2.99e-02	1.00e+00	5.046	1	2	13
GO:0005662	DNA replication factor A complex	2.99e-02	1.00e+00	5.046	1	3	13
GO:0030234	enzyme regulator activity	2.99e-02	1.00e+00	5.046	1	3	13
GO:0000738	DNA catabolic process, exonucleolytic	2.99e-02	1.00e+00	5.046	1	2	13
GO:0008266	poly(U) RNA binding	2.99e-02	1.00e+00	5.046	1	1	13
GO:0007020	microtubule nucleation	3.21e-02	1.00e+00	4.939	1	1	14
GO:0007095	mitotic G2 DNA damage checkpoint	3.21e-02	1.00e+00	4.939	1	1	14
GO:0006595	polyamine metabolic process	3.21e-02	1.00e+00	4.939	1	1	14
GO:0035066	positive regulation of histone acetylation	3.44e-02	1.00e+00	4.840	1	1	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	3.44e-02	1.00e+00	4.840	1	1	15
GO:0006261	DNA-dependent DNA replication	3.44e-02	1.00e+00	4.840	1	2	15
GO:0060749	mammary gland alveolus development	3.44e-02	1.00e+00	4.840	1	1	15
GO:0042176	regulation of protein catabolic process	3.66e-02	1.00e+00	4.747	1	3	16
GO:0005665	DNA-directed RNA polymerase II, core complex	3.66e-02	1.00e+00	4.747	1	4	16
GO:0050998	nitric-oxide synthase binding	3.66e-02	1.00e+00	4.747	1	1	16
GO:0051276	chromosome organization	3.66e-02	1.00e+00	4.747	1	4	16
GO:0001673	male germ cell nucleus	3.66e-02	1.00e+00	4.747	1	1	16
GO:0001056	RNA polymerase III activity	3.66e-02	1.00e+00	4.747	1	3	16
GO:0008408	3'-5' exonuclease activity	3.66e-02	1.00e+00	4.747	1	2	16
GO:0006413	translational initiation	3.72e-02	1.00e+00	2.713	2	12	131
GO:0000790	nuclear chromatin	3.83e-02	1.00e+00	2.691	2	7	133
GO:0010243	response to organonitrogen compound	3.89e-02	1.00e+00	4.659	1	2	17
GO:0006337	nucleosome disassembly	3.89e-02	1.00e+00	4.659	1	4	17
GO:0005666	DNA-directed RNA polymerase III complex	3.89e-02	1.00e+00	4.659	1	3	17
GO:0075733	intracellular transport of virus	3.89e-02	1.00e+00	4.659	1	2	17
GO:0007126	meiotic nuclear division	3.89e-02	1.00e+00	4.659	1	1	17
GO:0000086	G2/M transition of mitotic cell cycle	4.04e-02	1.00e+00	2.648	2	7	137
GO:0005525	GTP binding	4.04e-02	1.00e+00	1.974	3	11	328
GO:0006386	termination of RNA polymerase III transcription	4.11e-02	1.00e+00	4.577	1	3	18
GO:0071392	cellular response to estradiol stimulus	4.11e-02	1.00e+00	4.577	1	1	18
GO:0006541	glutamine metabolic process	4.11e-02	1.00e+00	4.577	1	1	18
GO:0031122	cytoplasmic microtubule organization	4.11e-02	1.00e+00	4.577	1	2	18
GO:0006385	transcription elongation from RNA polymerase III promoter	4.11e-02	1.00e+00	4.577	1	3	18
GO:0015949	nucleobase-containing small molecule interconversion	4.11e-02	1.00e+00	4.577	1	2	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	4.33e-02	1.00e+00	4.499	1	1	19
GO:0048863	stem cell differentiation	4.33e-02	1.00e+00	4.499	1	1	19
GO:0016887	ATPase activity	4.42e-02	1.00e+00	2.577	2	7	144
GO:0048873	homeostasis of number of cells within a tissue	4.56e-02	1.00e+00	4.425	1	1	20
GO:0008601	protein phosphatase type 2A regulator activity	4.56e-02	1.00e+00	4.425	1	3	20
GO:0005719	nuclear euchromatin	4.56e-02	1.00e+00	4.425	1	2	20
GO:0006457	protein folding	4.70e-02	1.00e+00	2.527	2	8	149
GO:0000718	nucleotide-excision repair, DNA damage removal	4.78e-02	1.00e+00	4.354	1	5	21
GO:0071364	cellular response to epidermal growth factor stimulus	4.78e-02	1.00e+00	4.354	1	1	21
GO:0003723	RNA binding	4.92e-02	1.00e+00	1.860	3	19	355
GO:0006297	nucleotide-excision repair, DNA gap filling	5.00e-02	1.00e+00	4.287	1	5	22
GO:0033574	response to testosterone	5.00e-02	1.00e+00	4.287	1	2	22
GO:0032201	telomere maintenance via semi-conservative replication	5.00e-02	1.00e+00	4.287	1	7	22
GO:0030863	cortical cytoskeleton	5.00e-02	1.00e+00	4.287	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	5.00e-02	1.00e+00	4.287	1	4	22
GO:0007052	mitotic spindle organization	5.00e-02	1.00e+00	4.287	1	2	22
GO:0031463	Cul3-RING ubiquitin ligase complex	5.22e-02	1.00e+00	4.223	1	2	23
GO:0043236	laminin binding	5.22e-02	1.00e+00	4.223	1	1	23
GO:0006513	protein monoubiquitination	5.22e-02	1.00e+00	4.223	1	1	23
GO:0000794	condensed nuclear chromosome	5.44e-02	1.00e+00	4.162	1	2	24
GO:0004864	protein phosphatase inhibitor activity	5.67e-02	1.00e+00	4.103	1	1	25
GO:0008536	Ran GTPase binding	5.67e-02	1.00e+00	4.103	1	2	25
GO:0005844	polysome	5.67e-02	1.00e+00	4.103	1	4	25
GO:0017144	drug metabolic process	5.67e-02	1.00e+00	4.103	1	1	25
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.82e-02	1.00e+00	2.354	2	5	168
GO:0000722	telomere maintenance via recombination	5.88e-02	1.00e+00	4.046	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	5.88e-02	1.00e+00	4.046	1	2	26
GO:0006730	one-carbon metabolic process	5.88e-02	1.00e+00	4.046	1	1	26
GO:0004003	ATP-dependent DNA helicase activity	6.10e-02	1.00e+00	3.992	1	3	27
GO:0006913	nucleocytoplasmic transport	6.10e-02	1.00e+00	3.992	1	2	27
GO:0016925	protein sumoylation	6.10e-02	1.00e+00	3.992	1	1	27
GO:0034080	CENP-A containing nucleosome assembly	6.10e-02	1.00e+00	3.992	1	2	27
GO:0030331	estrogen receptor binding	6.10e-02	1.00e+00	3.992	1	2	27
GO:0019894	kinesin binding	6.32e-02	1.00e+00	3.939	1	1	28
GO:0006099	tricarboxylic acid cycle	6.54e-02	1.00e+00	3.889	1	3	29
GO:0019005	SCF ubiquitin ligase complex	6.54e-02	1.00e+00	3.889	1	1	29
GO:0003730	mRNA 3'-UTR binding	6.54e-02	1.00e+00	3.889	1	2	29
GO:0003887	DNA-directed DNA polymerase activity	6.54e-02	1.00e+00	3.889	1	3	29
GO:0071897	DNA biosynthetic process	6.54e-02	1.00e+00	3.889	1	2	29
GO:0031625	ubiquitin protein ligase binding	6.57e-02	1.00e+00	2.255	2	13	180
GO:0006370	7-methylguanosine mRNA capping	6.76e-02	1.00e+00	3.840	1	4	30
GO:0006360	transcription from RNA polymerase I promoter	6.76e-02	1.00e+00	3.840	1	4	30
GO:0015629	actin cytoskeleton	6.76e-02	1.00e+00	2.231	2	5	183
GO:0045171	intercellular bridge	6.98e-02	1.00e+00	3.792	1	2	31
GO:0006271	DNA strand elongation involved in DNA replication	6.98e-02	1.00e+00	3.792	1	9	31
GO:0050661	NADP binding	7.19e-02	1.00e+00	3.747	1	1	32
GO:0031397	negative regulation of protein ubiquitination	7.19e-02	1.00e+00	3.747	1	1	32
GO:0034644	cellular response to UV	7.19e-02	1.00e+00	3.747	1	5	32
GO:0034332	adherens junction organization	8.06e-02	1.00e+00	3.577	1	1	36
GO:0001895	retina homeostasis	8.06e-02	1.00e+00	3.577	1	1	36
GO:0051084	'de novo' posttranslational protein folding	8.27e-02	1.00e+00	3.537	1	4	37
GO:0018107	peptidyl-threonine phosphorylation	8.27e-02	1.00e+00	3.537	1	1	37
GO:0051539	4 iron, 4 sulfur cluster binding	8.27e-02	1.00e+00	3.537	1	3	37
GO:0070527	platelet aggregation	8.49e-02	1.00e+00	3.499	1	2	38
GO:0050681	androgen receptor binding	8.49e-02	1.00e+00	3.499	1	4	38
GO:0008033	tRNA processing	8.70e-02	1.00e+00	3.461	1	1	39
GO:0006383	transcription from RNA polymerase III promoter	8.70e-02	1.00e+00	3.461	1	3	39
GO:0008026	ATP-dependent helicase activity	8.70e-02	1.00e+00	3.461	1	3	39
GO:0031490	chromatin DNA binding	8.70e-02	1.00e+00	3.461	1	2	39
GO:0006284	base-excision repair	8.70e-02	1.00e+00	3.461	1	7	39
GO:0022627	cytosolic small ribosomal subunit	8.70e-02	1.00e+00	3.461	1	3	39
GO:0032092	positive regulation of protein binding	8.70e-02	1.00e+00	3.461	1	3	39
GO:0007595	lactation	8.70e-02	1.00e+00	3.461	1	2	39
GO:0043195	terminal bouton	9.13e-02	1.00e+00	3.389	1	1	41
GO:0030521	androgen receptor signaling pathway	9.13e-02	1.00e+00	3.389	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	9.34e-02	1.00e+00	3.354	1	5	42
GO:0005739	mitochondrion	9.34e-02	1.00e+00	1.038	5	24	1046
GO:0014070	response to organic cyclic compound	9.55e-02	1.00e+00	3.320	1	3	43
GO:0010212	response to ionizing radiation	9.55e-02	1.00e+00	3.320	1	1	43
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	9.76e-02	1.00e+00	3.287	1	3	44
GO:0048146	positive regulation of fibroblast proliferation	9.76e-02	1.00e+00	3.287	1	2	44
GO:0007286	spermatid development	9.76e-02	1.00e+00	3.287	1	1	44
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9.76e-02	1.00e+00	3.287	1	2	44
GO:0050434	positive regulation of viral transcription	9.76e-02	1.00e+00	3.287	1	5	44
GO:0043966	histone H3 acetylation	9.97e-02	1.00e+00	3.255	1	2	45
GO:0055114	oxidation-reduction process	1.01e-01	1.00e+00	1.422	3	11	481
GO:0021762	substantia nigra development	1.02e-01	1.00e+00	3.223	1	1	46
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	1.04e-01	1.00e+00	3.192	1	3	47
GO:0042802	identical protein binding	1.05e-01	1.00e+00	1.392	3	18	491
GO:0019003	GDP binding	1.06e-01	1.00e+00	3.162	1	2	48
GO:0044267	cellular protein metabolic process	1.07e-01	1.00e+00	1.380	3	24	495
GO:0003743	translation initiation factor activity	1.08e-01	1.00e+00	3.132	1	4	49
GO:0035690	cellular response to drug	1.10e-01	1.00e+00	3.103	1	2	50
GO:0006091	generation of precursor metabolites and energy	1.12e-01	1.00e+00	3.074	1	3	51
GO:0000775	chromosome, centromeric region	1.14e-01	1.00e+00	3.046	1	2	52
GO:0008168	methyltransferase activity	1.14e-01	1.00e+00	3.046	1	1	52
GO:0060041	retina development in camera-type eye	1.16e-01	1.00e+00	3.019	1	3	53
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.18e-01	1.00e+00	2.992	1	2	54
GO:0043025	neuronal cell body	1.18e-01	1.00e+00	1.758	2	4	254
GO:0000226	microtubule cytoskeleton organization	1.21e-01	1.00e+00	2.965	1	3	55
GO:0000932	cytoplasmic mRNA processing body	1.23e-01	1.00e+00	2.939	1	3	56
GO:0000724	double-strand break repair via homologous recombination	1.25e-01	1.00e+00	2.914	1	6	57
GO:0030097	hemopoiesis	1.27e-01	1.00e+00	2.889	1	3	58
GO:0005840	ribosome	1.29e-01	1.00e+00	2.864	1	2	59
GO:0045216	cell-cell junction organization	1.29e-01	1.00e+00	2.864	1	2	59
GO:0000723	telomere maintenance	1.29e-01	1.00e+00	2.864	1	8	59
GO:0005643	nuclear pore	1.29e-01	1.00e+00	2.864	1	4	59
GO:0006302	double-strand break repair	1.35e-01	1.00e+00	2.792	1	8	62
GO:0006368	transcription elongation from RNA polymerase II promoter	1.45e-01	1.00e+00	2.680	1	6	67
GO:0006338	chromatin remodeling	1.47e-01	1.00e+00	2.659	1	4	68
GO:0050790	regulation of catalytic activity	1.49e-01	1.00e+00	2.638	1	3	69
GO:0042393	histone binding	1.53e-01	1.00e+00	2.597	1	3	71
GO:0034329	cell junction assembly	1.53e-01	1.00e+00	2.597	1	1	71
GO:0006200	ATP catabolic process	1.57e-01	1.00e+00	1.503	2	14	303
GO:0032355	response to estradiol	1.57e-01	1.00e+00	2.557	1	5	73
GO:0000785	chromatin	1.57e-01	1.00e+00	2.557	1	5	73
GO:0043086	negative regulation of catalytic activity	1.59e-01	1.00e+00	2.537	1	2	74
GO:0006767	water-soluble vitamin metabolic process	1.61e-01	1.00e+00	2.518	1	3	75
GO:0007265	Ras protein signal transduction	1.61e-01	1.00e+00	2.518	1	3	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	1.63e-01	1.00e+00	2.499	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	1.65e-01	1.00e+00	2.480	1	5	77
GO:0008584	male gonad development	1.65e-01	1.00e+00	2.480	1	2	77
GO:0006766	vitamin metabolic process	1.67e-01	1.00e+00	2.461	1	3	78
GO:0019901	protein kinase binding	1.71e-01	1.00e+00	1.425	2	21	320
GO:0007565	female pregnancy	1.71e-01	1.00e+00	2.425	1	2	80
GO:0019083	viral transcription	1.72e-01	1.00e+00	2.407	1	8	81
GO:0045087	innate immune response	1.72e-01	1.00e+00	1.065	3	20	616
GO:0001889	liver development	1.74e-01	1.00e+00	2.389	1	3	82
GO:0003682	chromatin binding	1.82e-01	1.00e+00	1.363	2	12	334
GO:0006415	translational termination	1.84e-01	1.00e+00	2.304	1	8	87
GO:0005813	centrosome	1.86e-01	1.00e+00	1.341	2	12	339
GO:0003690	double-stranded DNA binding	1.92e-01	1.00e+00	2.239	1	4	91
GO:0042470	melanosome	1.94e-01	1.00e+00	2.223	1	10	92
GO:0006928	cellular component movement	1.94e-01	1.00e+00	2.223	1	7	92
GO:0006414	translational elongation	1.95e-01	1.00e+00	2.207	1	11	93
GO:0051082	unfolded protein binding	1.99e-01	1.00e+00	2.177	1	6	95
GO:0071456	cellular response to hypoxia	2.05e-01	1.00e+00	2.132	1	4	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.16e-01	1.00e+00	2.046	1	8	104
GO:0014069	postsynaptic density	2.20e-01	1.00e+00	2.019	1	1	106
GO:0030496	midbody	2.25e-01	1.00e+00	1.978	1	4	109
GO:0005815	microtubule organizing center	2.27e-01	1.00e+00	1.965	1	4	110
GO:0015630	microtubule cytoskeleton	2.30e-01	1.00e+00	1.939	1	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.34e-01	1.00e+00	1.914	1	10	114
GO:0005819	spindle	2.34e-01	1.00e+00	1.914	1	7	114
GO:0072562	blood microparticle	2.38e-01	1.00e+00	1.889	1	4	116
GO:0044237	cellular metabolic process	2.41e-01	1.00e+00	1.864	1	3	118
GO:0043524	negative regulation of neuron apoptotic process	2.43e-01	1.00e+00	1.852	1	2	119
GO:0007219	Notch signaling pathway	2.54e-01	1.00e+00	1.781	1	4	125
GO:0005506	iron ion binding	2.57e-01	1.00e+00	1.758	1	3	127
GO:0006511	ubiquitin-dependent protein catabolic process	2.57e-01	1.00e+00	1.758	1	5	127
GO:0045892	negative regulation of transcription, DNA-templated	2.59e-01	1.00e+00	1.019	2	14	424
GO:0009615	response to virus	2.66e-01	1.00e+00	1.702	1	6	132
GO:0003735	structural constituent of ribosome	2.81e-01	1.00e+00	1.607	1	8	141
GO:0007507	heart development	2.81e-01	1.00e+00	1.607	1	5	141
GO:0061024	membrane organization	2.90e-01	1.00e+00	1.557	1	5	146
GO:0046777	protein autophosphorylation	3.09e-01	1.00e+00	1.443	1	3	158
GO:0045893	positive regulation of transcription, DNA-templated	3.14e-01	1.00e+00	0.819	2	17	487
GO:0006397	mRNA processing	3.27e-01	1.00e+00	1.346	1	3	169
GO:0030424	axon	3.32e-01	1.00e+00	1.320	1	3	172
GO:0016607	nuclear speck	3.36e-01	1.00e+00	1.295	1	4	175
GO:0004672	protein kinase activity	3.41e-01	1.00e+00	1.271	1	2	178
GO:0019904	protein domain specific binding	3.46e-01	1.00e+00	1.247	1	6	181
GO:0043687	post-translational protein modification	3.46e-01	1.00e+00	1.247	1	4	181
GO:0006367	transcription initiation from RNA polymerase II promoter	3.50e-01	1.00e+00	1.223	1	8	184
GO:0032403	protein complex binding	3.52e-01	1.00e+00	1.215	1	7	185
GO:0001701	in utero embryonic development	3.89e-01	1.00e+00	1.032	1	6	210
GO:0005622	intracellular	4.12e-01	1.00e+00	0.926	1	5	226
GO:0005759	mitochondrial matrix	4.21e-01	1.00e+00	0.882	1	12	233
GO:0042803	protein homodimerization activity	4.24e-01	1.00e+00	0.477	2	11	617
GO:0006412	translation	4.24e-01	1.00e+00	0.870	1	15	235
GO:0003713	transcription coactivator activity	4.29e-01	1.00e+00	0.846	1	10	239
GO:0005794	Golgi apparatus	4.50e-01	1.00e+00	0.402	2	14	650
GO:0004842	ubiquitin-protein transferase activity	4.52e-01	1.00e+00	0.747	1	4	256
GO:0000166	nucleotide binding	4.72e-01	1.00e+00	0.659	1	6	272
GO:0005975	carbohydrate metabolic process	4.75e-01	1.00e+00	0.648	1	5	274
GO:0006357	regulation of transcription from RNA polymerase II promoter	4.76e-01	1.00e+00	0.643	1	6	275
GO:0007283	spermatogenesis	4.77e-01	1.00e+00	0.638	1	6	276
GO:0019899	enzyme binding	4.92e-01	1.00e+00	0.577	1	11	288
GO:0007264	small GTPase mediated signal transduction	4.94e-01	1.00e+00	0.567	1	3	290
GO:0016567	protein ubiquitination	5.05e-01	1.00e+00	0.523	1	5	299
GO:0005743	mitochondrial inner membrane	5.06e-01	1.00e+00	0.518	1	5	300
GO:0005856	cytoskeleton	5.19e-01	1.00e+00	0.466	1	8	311
GO:0007411	axon guidance	5.37e-01	1.00e+00	0.393	1	9	327
GO:0008283	cell proliferation	5.41e-01	1.00e+00	0.376	1	12	331
GO:0043231	intracellular membrane-bounded organelle	5.42e-01	1.00e+00	0.371	1	8	332
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.70e-01	1.00e+00	0.083	2	19	811
GO:0043565	sequence-specific DNA binding	5.77e-01	1.00e+00	0.235	1	4	365
GO:0005925	focal adhesion	5.82e-01	1.00e+00	0.215	1	18	370
GO:0007155	cell adhesion	5.96e-01	1.00e+00	0.162	1	8	384
GO:0008284	positive regulation of cell proliferation	6.03e-01	1.00e+00	0.132	1	8	392
GO:0046982	protein heterodimerization activity	6.10e-01	1.00e+00	0.106	1	11	399
GO:0006366	transcription from RNA polymerase II promoter	6.34e-01	1.00e+00	0.015	1	12	425
GO:0007596	blood coagulation	6.66e-01	1.00e+00	-0.111	1	14	464
GO:0046872	metal ion binding	6.75e-01	1.00e+00	-0.185	3	24	1465
GO:0048471	perinuclear region of cytoplasm	7.10e-01	1.00e+00	-0.284	1	12	523
GO:0008270	zinc ion binding	7.20e-01	1.00e+00	-0.313	2	12	1067
GO:0006351	transcription, DNA-templated	7.28e-01	1.00e+00	-0.299	3	25	1585
GO:0005783	endoplasmic reticulum	7.65e-01	1.00e+00	-0.506	1	9	610
GO:0005789	endoplasmic reticulum membrane	7.80e-01	1.00e+00	-0.566	1	10	636
GO:0003677	DNA binding	8.34e-01	1.00e+00	-0.653	2	26	1351
GO:0007165	signal transduction	8.98e-01	1.00e+00	-1.145	1	17	950
GO:0005615	extracellular space	9.12e-01	1.00e+00	-1.234	1	17	1010
GO:0006355	regulation of transcription, DNA-templated	9.30e-01	1.00e+00	-1.362	1	17	1104
GO:0005886	plasma membrane	9.99e-01	1.00e+00	-2.722	1	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-55143

Interacting subnets

Genes (38)

Interactions (149)

Related GO terms (425)