reg-snw-6418

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.858	2.92e-07	1.56e-03	3.18e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-6418 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	25	0.807	0.973	67	-	-	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
PSMD11	5717	15	1.095	0.940	35	TF	Yes	-
CCNA2	890	10	0.550	0.973	246	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
[ SET ]	6418	1	0.317	0.858	30	-	-	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
RRM1	6240	3	0.587	0.872	78	-	Yes	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	RRM1	6240	pd	>	reg.ITFP.txt: no annot
CCNA2	890	RRM1	6240	pd	>	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
CCNA2	890	SET	6418	pd	>	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot

Related GO terms (160)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000278	mitotic cell cycle	1.72e-06	1.68e-02	4.281	5	35	314
GO:0005654	nucleoplasm	1.23e-05	1.20e-01	3.064	6	55	876
GO:0006206	pyrimidine nucleobase metabolic process	7.94e-05	7.75e-01	7.166	2	2	17
GO:0042995	cell projection	4.74e-04	1.00e+00	5.896	2	2	41
GO:0043234	protein complex	5.07e-04	1.00e+00	4.124	3	8	210
GO:0031100	organ regeneration	5.46e-04	1.00e+00	5.794	2	2	44
GO:0006334	nucleosome assembly	7.34e-04	1.00e+00	5.581	2	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	7.34e-04	1.00e+00	5.581	2	5	51
GO:0005829	cytosol	7.44e-04	1.00e+00	2.035	6	58	1787
GO:0004151	dihydroorotase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0070335	aspartate binding	8.19e-04	1.00e+00	10.253	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	8.19e-04	1.00e+00	10.253	1	1	1
GO:0016363	nuclear matrix	1.50e-03	1.00e+00	5.064	2	7	73
GO:0009263	deoxyribonucleotide biosynthetic process	1.64e-03	1.00e+00	9.253	1	1	2
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	1.64e-03	1.00e+00	9.253	1	1	2
GO:0006543	glutamine catabolic process	2.46e-03	1.00e+00	8.668	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006260	DNA replication	2.47e-03	1.00e+00	4.699	2	11	94
GO:0000086	G2/M transition of mitotic cell cycle	2.63e-03	1.00e+00	4.653	2	5	97
GO:0051414	response to cortisol	3.27e-03	1.00e+00	8.253	1	1	4
GO:0000212	meiotic spindle organization	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006228	UTP biosynthetic process	3.27e-03	1.00e+00	8.253	1	1	4
GO:0043248	proteasome assembly	3.27e-03	1.00e+00	8.253	1	1	4
GO:0001940	male pronucleus	3.27e-03	1.00e+00	8.253	1	1	4
GO:0014075	response to amine	4.09e-03	1.00e+00	7.931	1	1	5
GO:0005827	polar microtubule	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000930	gamma-tubulin complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0001939	female pronucleus	4.09e-03	1.00e+00	7.931	1	1	5
GO:0070062	extracellular vesicular exosome	4.77e-03	1.00e+00	1.895	5	43	1641
GO:0046134	pyrimidine nucleoside biosynthetic process	4.91e-03	1.00e+00	7.668	1	1	6
GO:0031000	response to caffeine	4.91e-03	1.00e+00	7.668	1	1	6
GO:0010389	regulation of G2/M transition of mitotic cell cycle	5.72e-03	1.00e+00	7.446	1	1	7
GO:0033762	response to glucagon	5.72e-03	1.00e+00	7.446	1	1	7
GO:0000812	Swr1 complex	5.72e-03	1.00e+00	7.446	1	2	7
GO:0031122	cytoplasmic microtubule organization	6.54e-03	1.00e+00	7.253	1	2	8
GO:0051290	protein heterotetramerization	6.54e-03	1.00e+00	7.253	1	1	8
GO:0035067	negative regulation of histone acetylation	6.54e-03	1.00e+00	7.253	1	1	8
GO:0031011	Ino80 complex	6.54e-03	1.00e+00	7.253	1	2	8
GO:0021846	cell proliferation in forebrain	7.35e-03	1.00e+00	7.083	1	1	9
GO:0008266	poly(U) RNA binding	7.35e-03	1.00e+00	7.083	1	1	9
GO:0007067	mitotic nuclear division	7.43e-03	1.00e+00	3.887	2	8	165
GO:0010467	gene expression	7.44e-03	1.00e+00	2.775	3	31	535
GO:0016071	mRNA metabolic process	7.87e-03	1.00e+00	3.844	2	21	170
GO:0043025	neuronal cell body	7.96e-03	1.00e+00	3.836	2	3	171
GO:0006541	glutamine metabolic process	8.17e-03	1.00e+00	6.931	1	1	10
GO:0004864	protein phosphatase inhibitor activity	8.17e-03	1.00e+00	6.931	1	1	10
GO:0043968	histone H2A acetylation	8.17e-03	1.00e+00	6.931	1	2	10
GO:0005838	proteasome regulatory particle	8.17e-03	1.00e+00	6.931	1	4	10
GO:0007020	microtubule nucleation	8.98e-03	1.00e+00	6.794	1	1	11
GO:0008601	protein phosphatase type 2A regulator activity	8.98e-03	1.00e+00	6.794	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	8.98e-03	1.00e+00	6.794	1	2	11
GO:0045120	pronucleus	8.98e-03	1.00e+00	6.794	1	1	11
GO:0016070	RNA metabolic process	9.56e-03	1.00e+00	3.699	2	21	188
GO:0035267	NuA4 histone acetyltransferase complex	9.79e-03	1.00e+00	6.668	1	3	12
GO:0048863	stem cell differentiation	9.79e-03	1.00e+00	6.668	1	1	12
GO:0015949	nucleobase-containing small molecule interconversion	9.79e-03	1.00e+00	6.668	1	2	12
GO:0006337	nucleosome disassembly	1.06e-02	1.00e+00	6.553	1	2	13
GO:0007095	mitotic G2 DNA damage checkpoint	1.06e-02	1.00e+00	6.553	1	1	13
GO:0016020	membrane	1.08e-02	1.00e+00	2.016	4	38	1207
GO:0022624	proteasome accessory complex	1.14e-02	1.00e+00	6.446	1	7	14
GO:0005515	protein binding	1.21e-02	1.00e+00	1.051	7	76	4124
GO:0071364	cellular response to epidermal growth factor stimulus	1.47e-02	1.00e+00	6.083	1	1	18
GO:0003678	DNA helicase activity	1.47e-02	1.00e+00	6.083	1	3	18
GO:0071339	MLL1 complex	1.47e-02	1.00e+00	6.083	1	2	18
GO:0033574	response to testosterone	1.47e-02	1.00e+00	6.083	1	1	18
GO:0000794	condensed nuclear chromosome	1.47e-02	1.00e+00	6.083	1	3	18
GO:0043044	ATP-dependent chromatin remodeling	1.63e-02	1.00e+00	5.931	1	2	20
GO:0006913	nucleocytoplasmic transport	1.63e-02	1.00e+00	5.931	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.63e-02	1.00e+00	5.931	1	2	20
GO:0017144	drug metabolic process	1.71e-02	1.00e+00	5.861	1	1	21
GO:0043967	histone H4 acetylation	1.79e-02	1.00e+00	5.794	1	2	22
GO:0005634	nucleus	1.93e-02	1.00e+00	1.174	6	67	3246
GO:0003730	mRNA 3'-UTR binding	2.03e-02	1.00e+00	5.610	1	2	25
GO:0031492	nucleosomal DNA binding	2.03e-02	1.00e+00	5.610	1	2	25
GO:0018107	peptidyl-threonine phosphorylation	2.35e-02	1.00e+00	5.395	1	2	29
GO:0010212	response to ionizing radiation	2.43e-02	1.00e+00	5.347	1	1	30
GO:0043195	terminal bouton	2.51e-02	1.00e+00	5.299	1	1	31
GO:0044281	small molecule metabolic process	2.59e-02	1.00e+00	2.117	3	32	844
GO:0007595	lactation	2.59e-02	1.00e+00	5.253	1	2	32
GO:0060041	retina development in camera-type eye	2.75e-02	1.00e+00	5.166	1	2	34
GO:0048146	positive regulation of fibroblast proliferation	2.83e-02	1.00e+00	5.124	1	1	35
GO:0000226	microtubule cytoskeleton organization	2.91e-02	1.00e+00	5.083	1	2	36
GO:0040008	regulation of growth	2.99e-02	1.00e+00	5.044	1	2	37
GO:0005524	ATP binding	3.00e-02	1.00e+00	2.037	3	23	892
GO:0035690	cellular response to drug	3.07e-02	1.00e+00	5.005	1	2	38
GO:0032508	DNA duplex unwinding	3.07e-02	1.00e+00	5.005	1	5	38
GO:0042802	identical protein binding	3.17e-02	1.00e+00	2.786	2	7	354
GO:0006521	regulation of cellular amino acid metabolic process	3.31e-02	1.00e+00	4.896	1	16	41
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	3.31e-02	1.00e+00	4.896	1	2	41
GO:0043086	negative regulation of catalytic activity	3.63e-02	1.00e+00	4.762	1	2	45
GO:0050790	regulation of catalytic activity	3.63e-02	1.00e+00	4.762	1	1	45
GO:0005737	cytoplasm	3.74e-02	1.00e+00	1.213	5	50	2633
GO:0000502	proteasome complex	3.79e-02	1.00e+00	4.699	1	17	47
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.95e-02	1.00e+00	4.639	1	3	49
GO:0006310	DNA recombination	4.03e-02	1.00e+00	4.610	1	6	50
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.18e-02	1.00e+00	4.553	1	17	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.26e-02	1.00e+00	4.525	1	17	53
GO:0042393	histone binding	4.34e-02	1.00e+00	4.499	1	3	54
GO:0005681	spliceosomal complex	4.42e-02	1.00e+00	4.472	1	2	55
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.50e-02	1.00e+00	4.446	1	17	56
GO:0008584	male gonad development	4.58e-02	1.00e+00	4.421	1	2	57
GO:0032355	response to estradiol	4.58e-02	1.00e+00	4.421	1	1	57
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	4.58e-02	1.00e+00	4.421	1	16	57
GO:0007265	Ras protein signal transduction	4.73e-02	1.00e+00	4.371	1	3	59
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.81e-02	1.00e+00	4.347	1	17	60
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	5	61
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.89e-02	1.00e+00	4.323	1	16	61
GO:0007565	female pregnancy	5.13e-02	1.00e+00	4.253	1	2	64
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.20e-02	1.00e+00	4.231	1	17	65
GO:0005200	structural constituent of cytoskeleton	5.44e-02	1.00e+00	4.166	1	2	68
GO:0006325	chromatin organization	5.59e-02	1.00e+00	4.124	1	3	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	5.59e-02	1.00e+00	4.124	1	16	70
GO:0001889	liver development	5.67e-02	1.00e+00	4.104	1	1	71
GO:0001649	osteoblast differentiation	5.91e-02	1.00e+00	4.044	1	2	74
GO:0005815	microtubule organizing center	6.14e-02	1.00e+00	3.987	1	1	77
GO:0030529	ribonucleoprotein complex	6.53e-02	1.00e+00	3.896	1	4	82
GO:0005635	nuclear envelope	6.60e-02	1.00e+00	3.878	1	4	83
GO:0043524	negative regulation of neuron apoptotic process	6.76e-02	1.00e+00	3.844	1	1	85
GO:0000209	protein polyubiquitination	7.30e-02	1.00e+00	3.730	1	16	92
GO:0006511	ubiquitin-dependent protein catabolic process	7.30e-02	1.00e+00	3.730	1	2	92
GO:0016887	ATPase activity	7.91e-02	1.00e+00	3.610	1	6	100
GO:0034641	cellular nitrogen compound metabolic process	8.29e-02	1.00e+00	3.539	1	18	105
GO:0007507	heart development	8.36e-02	1.00e+00	3.525	1	1	106
GO:0046777	protein autophosphorylation	8.36e-02	1.00e+00	3.525	1	2	106
GO:0000790	nuclear chromatin	8.59e-02	1.00e+00	3.485	1	3	109
GO:0042981	regulation of apoptotic process	8.82e-02	1.00e+00	3.446	1	18	112
GO:0003924	GTPase activity	9.35e-02	1.00e+00	3.359	1	3	119
GO:0004672	protein kinase activity	9.80e-02	1.00e+00	3.288	1	2	125
GO:0000082	G1/S transition of mitotic cell cycle	9.80e-02	1.00e+00	3.288	1	24	125
GO:0000398	mRNA splicing, via spliceosome	1.00e-01	1.00e+00	3.253	1	8	128
GO:0006184	GTP catabolic process	1.02e-01	1.00e+00	3.231	1	3	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.11e-01	1.00e+00	3.104	1	2	142
GO:0008380	RNA splicing	1.27e-01	1.00e+00	2.887	1	7	165
GO:0007283	spermatogenesis	1.30e-01	1.00e+00	2.861	1	2	168
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.794	1	6	176
GO:0005525	GTP binding	1.50e-01	1.00e+00	2.631	1	5	197
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.55e-01	1.00e+00	2.588	1	1	203
GO:0006281	DNA repair	1.55e-01	1.00e+00	2.588	1	19	203
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.539	1	4	210
GO:0043231	intracellular membrane-bounded organelle	1.65e-01	1.00e+00	2.485	1	7	218
GO:0005813	centrosome	1.65e-01	1.00e+00	2.492	1	8	217
GO:0019901	protein kinase binding	1.75e-01	1.00e+00	2.395	1	11	232
GO:0003723	RNA binding	1.85e-01	1.00e+00	2.305	1	11	247
GO:0055114	oxidation-reduction process	2.26e-01	1.00e+00	1.987	1	3	308
GO:0045892	negative regulation of transcription, DNA-templated	2.32e-01	1.00e+00	1.945	1	7	317
GO:0043066	negative regulation of apoptotic process	2.35e-01	1.00e+00	1.922	1	20	322
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	5	344
GO:0005730	nucleolus	2.63e-01	1.00e+00	1.004	2	41	1217
GO:0045893	positive regulation of transcription, DNA-templated	2.70e-01	1.00e+00	1.695	1	10	377
GO:0005783	endoplasmic reticulum	2.73e-01	1.00e+00	1.680	1	3	381
GO:0006915	apoptotic process	2.91e-01	1.00e+00	1.570	1	21	411
GO:0005794	Golgi apparatus	2.94e-01	1.00e+00	1.556	1	5	415
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	32	428
GO:0008270	zinc ion binding	4.62e-01	1.00e+00	0.748	1	7	727
GO:0044822	poly(A) RNA binding	4.95e-01	1.00e+00	0.611	1	25	799
GO:0003677	DNA binding	5.58e-01	1.00e+00	0.366	1	18	947
GO:0006351	transcription, DNA-templated	6.07e-01	1.00e+00	0.182	1	9	1076

Wolf-ratios-Mammosphere-Adherent

reg-snw-6418

Statistics

Genes (8)

Interactions (8)

Related GO terms (160)