meta-int-snw-10202

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-10202 wolf-screen-ratio-mammosphere-adherent 1.020 5.78e-19 3.38e-04 8.99e-03 14 13
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-1434 wolf-screen-ratio-mammosphere-adherent 0.865 2.23e-07 1.35e-03 2.78e-03 9 7
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
reg-snw-5686 wolf-screen-ratio-mammosphere-adherent 0.878 1.30e-07 1.01e-03 2.15e-03 5 4
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-10202 subnetwork

Genes (41)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
POLR2F 5435 620.8910.95626Yes-
CSE1L 1434 410.3040.86554Yes-
VARS 7407 860.5491.002204Yes-
DDX51 317781 530.0590.823210Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
CCNA2 890 540.5500.973246Yes-
PSMD1 5707 860.8360.830118Yes-
RPS11 6205 620.9931.113175Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
PRMT3 10196 490.4310.81526--
PSMA5 5686 350.3780.87833--
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
TREX1 11277 51-0.0510.88291Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
RPS3A 6189 400.8351.069166Yes-
CDC16 8881 530.9501.02080Yes-
RUVBL1 8607 950.7200.973469Yes-
DHRS2 10202 80.1601.02014--
PSMD3 5709 1000.9861.106201Yes-
RPL14 9045 491.2501.113166Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
SAP18 10284 201.1151.06957Yes-
PSMD6 9861 790.8480.878143Yes-

Interactions (200)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
RPS11 6205 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMA5 5686 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
CSE1L 1434 PSMD14 10213 pd < reg.ITFP.txt: no annot
CSE1L 1434 RAN 5901 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, HPRD, IntAct_Yeast, MIPS, IntAct, INTEROLOG;
int.HPRD: in vitro
CAD 790 CDC16 8881 pp -- int.I2D: IntAct_Yeast
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
PSMA5 5686 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMA5 5686 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BIND_Yeast, IntAct_Fly, Krogan_Core
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
CCNA2 890 CSE1L 1434 pd > reg.ITFP.txt: no annot
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
RPS3A 6189 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
RPS3A 6189 DHRS2 10202 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPA1 6117 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RPS3A 6189 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
RPS3A 6189 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
MTHFD1 4522 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPS3A 6189 SAP18 10284 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
RPS3A 6189 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMA5 5686 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastHigh, Yu_GoldStd, Krogan_Core, MINT_Yeast
CSE1L 1434 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA5 5686 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, YeastHigh
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
ACTB 60 DHRS2 10202 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
RPL14 9045 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
PSMA5 5686 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
RPS11 6205 DDX51 317781 pp -- int.I2D: IntAct_Yeast
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD6 9861 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA5 5686 POLE4 56655 pd < reg.ITFP.txt: no annot
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMA5 5686 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA3 5684 PSMA5 5686 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Mouse, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core, Tarassov_PCA
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMB3 5691 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMA5 5686 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastHigh
CCNA2 890 RPA1 6117 pp -- int.I2D: BioGrid
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
RPS11 6205 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (402)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.83e-242.99e-206.422142465
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.75e-249.39e-206.315142470
GO:0006521regulation of cellular amino acid metabolic process6.32e-241.03e-196.693132150
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.35e-232.20e-196.235142474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.65e-235.96e-196.140142579
GO:0000502proteasome complex5.55e-239.06e-196.479132258
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.86e-224.66e-186.315132265
GO:0016071mRNA metabolic process1.24e-212.02e-174.9231734223
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.48e-212.42e-176.148132373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.14e-215.12e-176.071132377
GO:0000082G1/S transition of mitotic cell cycle7.13e-211.16e-165.3151533150
GO:0016070RNA metabolic process7.23e-211.18e-164.7761734247
GO:0010467gene expression2.53e-204.13e-163.7102258669
GO:0002474antigen processing and presentation of peptide antigen via MHC class I5.00e-208.17e-165.783132394
GO:0005654nucleoplasm1.30e-192.13e-153.18425831095
GO:0016032viral process2.47e-194.02e-153.8822055540
GO:0000278mitotic cell cycle7.68e-191.25e-144.1701852398
GO:0000209protein polyubiquitination8.82e-191.44e-145.4791321116
GO:0042981regulation of apoptotic process3.04e-174.96e-135.0991326151
GO:0005839proteasome core complex3.29e-175.38e-137.46781118
GO:0004298threonine-type endopeptidase activity9.45e-171.54e-127.31581120
GO:0034641cellular nitrogen compound metabolic process2.49e-164.06e-124.8701325177
GO:0005829cytosol4.68e-157.64e-112.172291252562
GO:0043066negative regulation of apoptotic process6.03e-149.84e-103.7861530433
GO:0070062extracellular vesicular exosome4.01e-136.54e-092.09527982516
GO:0006915apoptotic process5.18e-118.46e-073.2871434571
GO:0022624proteasome accessory complex4.70e-107.68e-066.8715917
GO:0019773proteasome core complex, alpha-subunit complex2.38e-093.89e-057.637458
GO:0005730nucleolus3.17e-085.17e-042.08918701684
GO:0044281small molecule metabolic process3.45e-085.63e-042.29816571295
GO:0005634nucleus6.16e-081.01e-031.258291314828
GO:0016020membrane3.57e-075.83e-031.95517801746
GO:0005838proteasome regulatory particle3.19e-065.20e-026.6373712
GO:0006281DNA repair3.76e-066.14e-023.400722264
GO:0005515protein binding3.76e-066.14e-020.963301726127
GO:0035267NuA4 histone acetyltransferase complex5.25e-068.58e-026.4143414
GO:0019058viral life cycle9.74e-061.59e-014.113510115
GO:0006298mismatch repair1.63e-052.66e-015.9003620
GO:0006413translational initiation1.83e-052.99e-013.925512131
GO:0006310DNA recombination2.34e-053.82e-014.5714467
GO:0019083viral transcription4.96e-058.09e-014.2974881
GO:0000730DNA recombinase assembly6.13e-051.00e+007.315235
GO:0006415translational termination6.56e-051.00e+004.1944887
GO:0006414translational elongation8.51e-051.00e+004.09841193
GO:0022627cytosolic small ribosomal subunit1.26e-041.00e+004.9363339
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.31e-041.00e+003.93648104
GO:0000812Swr1 complex1.71e-041.00e+006.637238
GO:0005737cytoplasm1.83e-041.00e+001.07221983976
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.87e-041.00e+003.804410114
GO:0030529ribonucleoprotein complex1.87e-041.00e+003.80448114
GO:0006283transcription-coupled nucleotide-excision repair2.07e-041.00e+004.6983846
GO:0003684damaged DNA binding2.82e-041.00e+004.54931151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding3.34e-041.00e+004.4673554
GO:0000724double-strand break repair via homologous recombination3.92e-041.00e+004.3893657
GO:0043968histone H2A acetylation4.00e-041.00e+006.0522312
GO:0003735structural constituent of ribosome4.22e-041.00e+003.49748141
GO:0042273ribosomal large subunit biogenesis4.72e-041.00e+005.9362413
GO:0005662DNA replication factor A complex4.72e-041.00e+005.9362313
GO:0030234enzyme regulator activity4.72e-041.00e+005.9362313
GO:0031011Ino80 complex5.50e-041.00e+005.8302314
GO:0006289nucleotide-excision repair6.87e-041.00e+004.11331269
GO:0003697single-stranded DNA binding6.87e-041.00e+004.1133969
GO:0042176regulation of protein catabolic process7.23e-041.00e+005.6372316
GO:0006259DNA metabolic process1.02e-031.00e+005.3892319
GO:0003678DNA helicase activity1.02e-031.00e+005.3892319
GO:0044822poly(A) RNA binding1.18e-031.00e+001.7339501078
GO:0000718nucleotide-excision repair, DNA damage removal1.25e-031.00e+005.2452521
GO:0006297nucleotide-excision repair, DNA gap filling1.38e-031.00e+005.1772522
GO:0032201telomere maintenance via semi-conservative replication1.38e-031.00e+005.1772722
GO:0043044ATP-dependent chromatin remodeling1.51e-031.00e+005.1132423
GO:0016363nuclear matrix1.58e-031.00e+003.69831192
GO:0006611protein export from nucleus1.78e-031.00e+004.9932425
GO:0000722telomere maintenance via recombination1.93e-031.00e+004.9362726
GO:0071339MLL1 complex2.08e-031.00e+004.8822327
GO:0043022ribosome binding2.23e-031.00e+004.8302328
GO:0043967histone H4 acetylation2.23e-031.00e+004.8302328
GO:0031492nucleosomal DNA binding2.23e-031.00e+004.8302428
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.51e-031.00e+008.637111
GO:0070335aspartate binding2.51e-031.00e+008.637111
GO:0008262importin-alpha export receptor activity2.51e-031.00e+008.637111
GO:0008541proteasome regulatory particle, lid subcomplex2.51e-031.00e+008.637111
GO:0032558adenyl deoxyribonucleotide binding2.51e-031.00e+008.637111
GO:0004151dihydroorotase activity2.51e-031.00e+008.637111
GO:0000054ribosomal subunit export from nucleus2.51e-031.00e+008.637111
GO:0004070aspartate carbamoyltransferase activity2.51e-031.00e+008.637111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.51e-031.00e+008.637111
GO:0007067mitotic nuclear division2.63e-031.00e+002.785413231
GO:0008380RNA splicing2.67e-031.00e+002.779413232
GO:0006271DNA strand elongation involved in DNA replication2.73e-031.00e+004.6832931
GO:0006412translation2.79e-031.00e+002.760415235
GO:0006325chromatin organization3.61e-031.00e+003.27934123
GO:0006260DNA replication3.78e-031.00e+003.256312125
GO:0006284base-excision repair4.30e-031.00e+004.3512739
GO:0032508DNA duplex unwinding4.97e-031.00e+004.2452442
GO:0004832valine-tRNA ligase activity5.02e-031.00e+007.637112
GO:0006407rRNA export from nucleus5.02e-031.00e+007.637112
GO:0006438valyl-tRNA aminoacylation5.02e-031.00e+007.637112
GO:0000105histidine biosynthetic process5.02e-031.00e+007.637112
GO:0008207C21-steroid hormone metabolic process5.02e-031.00e+007.637112
GO:00082963'-5'-exodeoxyribonuclease activity5.02e-031.00e+007.637112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.02e-031.00e+007.637112
GO:0005055laminin receptor activity5.02e-031.00e+007.637112
GO:0070409carbamoyl phosphate biosynthetic process5.02e-031.00e+007.637112
GO:0016887ATPase activity5.61e-031.00e+003.05237144
GO:0031100organ regeneration6.99e-031.00e+003.9932450
GO:0040008regulation of growth7.26e-031.00e+003.9642351
GO:0061574ASAP complex7.52e-031.00e+007.052113
GO:0071899negative regulation of estrogen receptor binding7.52e-031.00e+007.052113
GO:0071733transcriptional activation by promoter-enhancer looping7.52e-031.00e+007.052113
GO:0000056ribosomal small subunit export from nucleus7.52e-031.00e+007.052113
GO:0044205'de novo' UMP biosynthetic process7.52e-031.00e+007.052113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process7.52e-031.00e+007.052113
GO:0044267cellular protein metabolic process7.66e-031.00e+002.008524495
GO:0000398mRNA splicing, via spliceosome8.16e-031.00e+002.856312165
GO:0005840ribosome9.62e-031.00e+003.7542259
GO:0000723telomere maintenance9.62e-031.00e+003.7542859
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.00e-021.00e+006.637114
GO:0000212meiotic spindle organization1.00e-021.00e+006.637114
GO:003068690S preribosome1.00e-021.00e+006.637114
GO:0019788NEDD8 ligase activity1.00e-021.00e+006.637114
GO:0016274protein-arginine N-methyltransferase activity1.00e-021.00e+006.637114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity1.00e-021.00e+006.637114
GO:0004329formate-tetrahydrofolate ligase activity1.00e-021.00e+006.637114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.00e-021.00e+006.637114
GO:0034969histone arginine methylation1.00e-021.00e+006.637114
GO:0006543glutamine catabolic process1.00e-021.00e+006.637114
GO:0009396folic acid-containing compound biosynthetic process1.00e-021.00e+006.637114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity1.00e-021.00e+006.637114
GO:0031467Cul7-RING ubiquitin ligase complex1.00e-021.00e+006.637114
GO:0004090carbonyl reductase (NADPH) activity1.00e-021.00e+006.637114
GO:0000055ribosomal large subunit export from nucleus1.00e-021.00e+006.637114
GO:0008853exodeoxyribonuclease III activity1.00e-021.00e+006.637114
GO:0032481positive regulation of type I interferon production1.03e-021.00e+003.7062661
GO:0006302double-strand break repair1.06e-021.00e+003.6832862
GO:0003723RNA binding1.18e-021.00e+002.165419355
GO:0051414response to cortisol1.25e-021.00e+006.315115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.25e-021.00e+006.315125
GO:0042256mature ribosome assembly1.25e-021.00e+006.315115
GO:0001940male pronucleus1.25e-021.00e+006.315115
GO:0009086methionine biosynthetic process1.25e-021.00e+006.315115
GO:0032407MutSalpha complex binding1.25e-021.00e+006.315115
GO:2000001regulation of DNA damage checkpoint1.25e-021.00e+006.315115
GO:0008622epsilon DNA polymerase complex1.25e-021.00e+006.315115
GO:0031461cullin-RING ubiquitin ligase complex1.25e-021.00e+006.315115
GO:0071169establishment of protein localization to chromatin1.25e-021.00e+006.315115
GO:0043248proteasome assembly1.25e-021.00e+006.315115
GO:0030891VCB complex1.25e-021.00e+006.315125
GO:0005827polar microtubule1.25e-021.00e+006.315115
GO:0005638lamin filament1.25e-021.00e+006.315115
GO:0061133endopeptidase activator activity1.25e-021.00e+006.315115
GO:0003924GTPase activity1.43e-021.00e+002.55739203
GO:0002181cytoplasmic translation1.50e-021.00e+006.052116
GO:0043023ribosomal large subunit binding1.50e-021.00e+006.052126
GO:0031466Cul5-RING ubiquitin ligase complex1.50e-021.00e+006.052116
GO:0030957Tat protein binding1.50e-021.00e+006.052146
GO:0046134pyrimidine nucleoside biosynthetic process1.50e-021.00e+006.052116
GO:0032405MutLalpha complex binding1.50e-021.00e+006.052126
GO:0008469histone-arginine N-methyltransferase activity1.50e-021.00e+006.052116
GO:0071013catalytic step 2 spliceosome1.68e-021.00e+003.3332779
GO:0010950positive regulation of endopeptidase activity1.75e-021.00e+005.830117
GO:0000028ribosomal small subunit assembly1.75e-021.00e+005.830117
GO:0002161aminoacyl-tRNA editing activity1.75e-021.00e+005.830127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.75e-021.00e+005.830117
GO:0001939female pronucleus1.75e-021.00e+005.830117
GO:0031462Cul2-RING ubiquitin ligase complex1.75e-021.00e+005.830127
GO:0035999tetrahydrofolate interconversion1.75e-021.00e+005.830117
GO:0072341modified amino acid binding1.75e-021.00e+005.830117
GO:0000930gamma-tubulin complex1.75e-021.00e+005.830117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.75e-021.00e+005.830117
GO:0006184GTP catabolic process1.77e-021.00e+002.44039220
GO:0005681spliceosomal complex1.84e-021.00e+003.2622383
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.99e-021.00e+005.637128
GO:0001055RNA polymerase II activity1.99e-021.00e+005.637138
GO:0070688MLL5-L complex1.99e-021.00e+005.637118
GO:0045116protein neddylation1.99e-021.00e+005.637128
GO:0000800lateral element1.99e-021.00e+005.637118
GO:0006164purine nucleotide biosynthetic process1.99e-021.00e+005.637128
GO:0014075response to amine2.24e-021.00e+005.467119
GO:0016605PML body2.24e-021.00e+003.1132592
GO:0006228UTP biosynthetic process2.24e-021.00e+005.467119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.24e-021.00e+005.467119
GO:0031000response to caffeine2.24e-021.00e+005.467129
GO:0005200structural constituent of cytoskeleton2.28e-021.00e+003.0982793
GO:0001649osteoblast differentiation2.37e-021.00e+003.0672695
GO:0006364rRNA processing2.42e-021.00e+003.0522596
GO:0070628proteasome binding2.48e-021.00e+005.3151110
GO:0046655folic acid metabolic process2.48e-021.00e+005.3151110
GO:0006450regulation of translational fidelity2.48e-021.00e+005.3151210
GO:0010569regulation of double-strand break repair via homologous recombination2.73e-021.00e+005.1771111
GO:0031571mitotic G1 DNA damage checkpoint2.73e-021.00e+005.1771311
GO:0001054RNA polymerase I activity2.73e-021.00e+005.1771311
GO:0045120pronucleus2.73e-021.00e+005.1771111
GO:0033762response to glucagon2.73e-021.00e+005.1771111
GO:0035458cellular response to interferon-beta2.73e-021.00e+005.1771211
GO:0061136regulation of proteasomal protein catabolic process2.97e-021.00e+005.0521112
GO:00709353'-UTR-mediated mRNA stabilization2.97e-021.00e+005.0521212
GO:0005736DNA-directed RNA polymerase I complex2.97e-021.00e+005.0521312
GO:0032479regulation of type I interferon production3.22e-021.00e+004.9361213
GO:0000738DNA catabolic process, exonucleolytic3.22e-021.00e+004.9361213
GO:0008266poly(U) RNA binding3.22e-021.00e+004.9361113
GO:0005635nuclear envelope3.43e-021.00e+002.77926116
GO:0007020microtubule nucleation3.46e-021.00e+004.8301114
GO:0007095mitotic G2 DNA damage checkpoint3.46e-021.00e+004.8301114
GO:0043011myeloid dendritic cell differentiation3.70e-021.00e+004.7301115
GO:0035066positive regulation of histone acetylation3.70e-021.00e+004.7301115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.70e-021.00e+004.7301115
GO:0048025negative regulation of mRNA splicing, via spliceosome3.70e-021.00e+004.7301115
GO:0006261DNA-dependent DNA replication3.70e-021.00e+004.7301215
GO:0043234protein complex3.92e-021.00e+001.993317300
GO:0005665DNA-directed RNA polymerase II, core complex3.95e-021.00e+004.6371416
GO:0050998nitric-oxide synthase binding3.95e-021.00e+004.6371116
GO:0001673male germ cell nucleus3.95e-021.00e+004.6371116
GO:0001056RNA polymerase III activity3.95e-021.00e+004.6371316
GO:00084083'-5' exonuclease activity3.95e-021.00e+004.6371216
GO:0006200ATP catabolic process4.02e-021.00e+001.979314303
GO:0006511ubiquitin-dependent protein catabolic process4.04e-021.00e+002.64825127
GO:0010243response to organonitrogen compound4.19e-021.00e+004.5491217
GO:0005666DNA-directed RNA polymerase III complex4.19e-021.00e+004.5491317
GO:0075733intracellular transport of virus4.19e-021.00e+004.5491217
GO:0007126meiotic nuclear division4.19e-021.00e+004.5491117
GO:0000790nuclear chromatin4.40e-021.00e+002.58227133
GO:0070536protein K63-linked deubiquitination4.43e-021.00e+004.4671118
GO:0006386termination of RNA polymerase III transcription4.43e-021.00e+004.4671318
GO:0071392cellular response to estradiol stimulus4.43e-021.00e+004.4671118
GO:0006541glutamine metabolic process4.43e-021.00e+004.4671118
GO:0031122cytoplasmic microtubule organization4.43e-021.00e+004.4671218
GO:0035861site of double-strand break4.43e-021.00e+004.4671118
GO:0006385transcription elongation from RNA polymerase III promoter4.43e-021.00e+004.4671318
GO:0006303double-strand break repair via nonhomologous end joining4.43e-021.00e+004.4671318
GO:0000086G2/M transition of mitotic cell cycle4.64e-021.00e+002.53927137
GO:0035145exon-exon junction complex4.67e-021.00e+004.3891219
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.67e-021.00e+004.3891119
GO:0048863stem cell differentiation4.67e-021.00e+004.3891119
GO:0007088regulation of mitosis4.67e-021.00e+004.3891119
GO:0005525GTP binding4.89e-021.00e+001.864311328
GO:0048873homeostasis of number of cells within a tissue4.91e-021.00e+004.3151120
GO:0005680anaphase-promoting complex4.91e-021.00e+004.3151420
GO:0005719nuclear euchromatin4.91e-021.00e+004.3151220
GO:0005524ATP binding4.97e-021.00e+001.0417461354
GO:0071364cellular response to epidermal growth factor stimulus5.15e-021.00e+004.2451121
GO:0005813centrosome5.30e-021.00e+001.817312339
GO:0006457protein folding5.38e-021.00e+002.41828149
GO:0033574response to testosterone5.39e-021.00e+004.1771222
GO:0030863cortical cytoskeleton5.39e-021.00e+004.1771122
GO:0036464cytoplasmic ribonucleoprotein granule5.39e-021.00e+004.1771422
GO:0007052mitotic spindle organization5.39e-021.00e+004.1771222
GO:0031463Cul3-RING ubiquitin ligase complex5.62e-021.00e+004.1131223
GO:0043236laminin binding5.62e-021.00e+004.1131123
GO:0006513protein monoubiquitination5.62e-021.00e+004.1131123
GO:0000794condensed nuclear chromosome5.86e-021.00e+004.0521224
GO:0006206pyrimidine nucleobase metabolic process5.86e-021.00e+004.0521224
GO:0008536Ran GTPase binding6.10e-021.00e+003.9931225
GO:0005844polysome6.10e-021.00e+003.9931425
GO:0017144drug metabolic process6.10e-021.00e+003.9931125
GO:0070979protein K11-linked ubiquitination6.34e-021.00e+003.9361326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.34e-021.00e+003.9361226
GO:0006730one-carbon metabolic process6.34e-021.00e+003.9361126
GO:0005925focal adhesion6.55e-021.00e+001.690318370
GO:0004003ATP-dependent DNA helicase activity6.57e-021.00e+003.8821327
GO:0034080CENP-A containing nucleosome assembly6.57e-021.00e+003.8821227
GO:0019843rRNA binding6.57e-021.00e+003.8821327
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.65e-021.00e+002.24525168
GO:0006397mRNA processing6.72e-021.00e+002.23623169
GO:0000118histone deacetylase complex6.81e-021.00e+003.8301128
GO:0019894kinesin binding6.81e-021.00e+003.8301128
GO:0000381regulation of alternative mRNA splicing, via spliceosome7.04e-021.00e+003.7791229
GO:0019005SCF ubiquitin ligase complex7.04e-021.00e+003.7791129
GO:0003730mRNA 3'-UTR binding7.04e-021.00e+003.7791229
GO:0003887DNA-directed DNA polymerase activity7.04e-021.00e+003.7791329
GO:0071897DNA biosynthetic process7.04e-021.00e+003.7791229
GO:0016607nuclear speck7.14e-021.00e+002.18624175
GO:00063707-methylguanosine mRNA capping7.27e-021.00e+003.7301430
GO:0006360transcription from RNA polymerase I promoter7.27e-021.00e+003.7301430
GO:0031625ubiquitin protein ligase binding7.50e-021.00e+002.145213180
GO:0007094mitotic spindle assembly checkpoint7.51e-021.00e+003.6831531
GO:0015629actin cytoskeleton7.71e-021.00e+002.12125183
GO:0031397negative regulation of protein ubiquitination7.74e-021.00e+003.6371132
GO:0034644cellular response to UV7.74e-021.00e+003.6371532
GO:1903507negative regulation of nucleic acid-templated transcription7.74e-021.00e+003.6371232
GO:0005876spindle microtubule8.20e-021.00e+003.5491334
GO:0034332adherens junction organization8.67e-021.00e+003.4671136
GO:0004221ubiquitin thiolesterase activity8.67e-021.00e+003.4671236
GO:0001895retina homeostasis8.67e-021.00e+003.4671136
GO:0034599cellular response to oxidative stress8.67e-021.00e+003.4671136
GO:0051084'de novo' posttranslational protein folding8.90e-021.00e+003.4271437
GO:0018107peptidyl-threonine phosphorylation8.90e-021.00e+003.4271137
GO:0070527platelet aggregation9.13e-021.00e+003.3891238
GO:0050681androgen receptor binding9.13e-021.00e+003.3891438
GO:0006383transcription from RNA polymerase III promoter9.35e-021.00e+003.3511339
GO:0008026ATP-dependent helicase activity9.35e-021.00e+003.3511339
GO:0031490chromatin DNA binding9.35e-021.00e+003.3511239
GO:0032092positive regulation of protein binding9.35e-021.00e+003.3511339
GO:0007595lactation9.35e-021.00e+003.3511239
GO:0000781chromosome, telomeric region9.58e-021.00e+003.3151240
GO:0043195terminal bouton9.81e-021.00e+003.2791141
GO:0030521androgen receptor signaling pathway9.81e-021.00e+003.2791241
GO:0006418tRNA aminoacylation for protein translation1.00e-011.00e+003.2451542
GO:0014070response to organic cyclic compound1.03e-011.00e+003.2111343
GO:0048146positive regulation of fibroblast proliferation1.05e-011.00e+003.1771244
GO:0007286spermatid development1.05e-011.00e+003.1771144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.05e-011.00e+003.1771244
GO:0050434positive regulation of viral transcription1.05e-011.00e+003.1771544
GO:0015030Cajal body1.07e-011.00e+003.1451245
GO:0043966histone H3 acetylation1.07e-011.00e+003.1451245
GO:0021762substantia nigra development1.09e-011.00e+003.1131146
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.12e-011.00e+003.0821347
GO:0019003GDP binding1.14e-011.00e+003.0521248
GO:0003743translation initiation factor activity1.16e-011.00e+003.0221449
GO:0022625cytosolic large ribosomal subunit1.16e-011.00e+003.0221549
GO:0035690cellular response to drug1.18e-011.00e+002.9931250
GO:0008168methyltransferase activity1.23e-011.00e+002.9361152
GO:0042802identical protein binding1.25e-011.00e+001.282318491
GO:0090305nucleic acid phosphodiester bond hydrolysis1.27e-011.00e+002.8821254
GO:0000226microtubule cytoskeleton organization1.29e-011.00e+002.8561355
GO:0000932cytoplasmic mRNA processing body1.32e-011.00e+002.8301356
GO:0030097hemopoiesis1.36e-011.00e+002.7791358
GO:0008237metallopeptidase activity1.36e-011.00e+002.7791158
GO:0045216cell-cell junction organization1.38e-011.00e+002.7541259
GO:0005643nuclear pore1.38e-011.00e+002.7541459
GO:0019903protein phosphatase binding1.47e-011.00e+002.6601463
GO:0042995cell projection1.47e-011.00e+002.6601663
GO:0006357regulation of transcription from RNA polymerase II promoter1.52e-011.00e+001.53426275
GO:0009636response to toxic substance1.53e-011.00e+002.5921166
GO:0006368transcription elongation from RNA polymerase II promoter1.55e-011.00e+002.5711667
GO:0006338chromatin remodeling1.58e-011.00e+002.5491468
GO:0019899enzyme binding1.63e-011.00e+001.467211288
GO:0034329cell junction assembly1.64e-011.00e+002.4871171
GO:0032355response to estradiol1.68e-011.00e+002.4471573
GO:0000785chromatin1.68e-011.00e+002.4471573
GO:0055086nucleobase-containing small molecule metabolic process1.68e-011.00e+002.4471573
GO:0006767water-soluble vitamin metabolic process1.72e-011.00e+002.4081375
GO:0007265Ras protein signal transduction1.72e-011.00e+002.4081375
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.74e-011.00e+002.3891376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.76e-011.00e+002.3701577
GO:0006766vitamin metabolic process1.79e-011.00e+002.3511378
GO:0006334nucleosome assembly1.81e-011.00e+002.3331479
GO:0007565female pregnancy1.83e-011.00e+002.3151280
GO:0001889liver development1.87e-011.00e+002.2791382
GO:0019901protein kinase binding1.92e-011.00e+001.315221320
GO:0047485protein N-terminus binding1.95e-011.00e+002.2111486
GO:0045087innate immune response2.01e-011.00e+000.955320616
GO:0008283cell proliferation2.02e-011.00e+001.266212331
GO:0003690double-stranded DNA binding2.05e-011.00e+002.1291491
GO:0003682chromatin binding2.05e-011.00e+001.253212334
GO:0042470melanosome2.07e-011.00e+002.11311092
GO:0006928cellular component movement2.07e-011.00e+002.1131792
GO:0051082unfolded protein binding2.13e-011.00e+002.0671695
GO:0071456cellular response to hypoxia2.19e-011.00e+002.0221498
GO:0014069postsynaptic density2.35e-011.00e+001.90911106
GO:0005815microtubule organizing center2.42e-011.00e+001.85614110
GO:0015630microtubule cytoskeleton2.46e-011.00e+001.83015112
GO:0005819spindle2.50e-011.00e+001.80417114
GO:0072562blood microparticle2.54e-011.00e+001.77914116
GO:0005739mitochondrion2.67e-011.00e+000.6064241046
GO:0007219Notch signaling pathway2.71e-011.00e+001.67114125
GO:0009615response to virus2.83e-011.00e+001.59216132
GO:0007507heart development3.00e-011.00e+001.49715141
GO:0061024membrane organization3.08e-011.00e+001.44715146
GO:0046777protein autophosphorylation3.29e-011.00e+001.33313158
GO:0055114oxidation-reduction process3.42e-011.00e+000.727211481
GO:0045893positive regulation of transcription, DNA-templated3.47e-011.00e+000.709217487
GO:0030424axon3.53e-011.00e+001.21113172
GO:0004672protein kinase activity3.62e-011.00e+001.16112178
GO:0003714transcription corepressor activity3.64e-011.00e+001.15317179
GO:0019904protein domain specific binding3.67e-011.00e+001.13716181
GO:0006367transcription initiation from RNA polymerase II promoter3.72e-011.00e+001.11318184
GO:0032403protein complex binding3.74e-011.00e+001.10617185
GO:0001701in utero embryonic development4.12e-011.00e+000.92316210
GO:0005622intracellular4.36e-011.00e+000.81715226
GO:0005759mitochondrial matrix4.46e-011.00e+000.773112233
GO:0003713transcription coactivator activity4.54e-011.00e+000.736110239
GO:0043025neuronal cell body4.75e-011.00e+000.64814254
GO:0004842ubiquitin-protein transferase activity4.77e-011.00e+000.63714256
GO:0005794Golgi apparatus4.90e-011.00e+000.293214650
GO:0000166nucleotide binding4.98e-011.00e+000.54916272
GO:0043065positive regulation of apoptotic process5.01e-011.00e+000.53918274
GO:0007283spermatogenesis5.03e-011.00e+000.52816276
GO:0046872metal ion binding5.09e-011.00e+000.1204241465
GO:0007264small GTPase mediated signal transduction5.21e-011.00e+000.45713290
GO:0016567protein ubiquitination5.32e-011.00e+000.41315299
GO:0005856cytoskeleton5.46e-011.00e+000.35618311
GO:0030154cell differentiation5.62e-011.00e+000.29315325
GO:0007411axon guidance5.64e-011.00e+000.28419327
GO:0043231intracellular membrane-bounded organelle5.70e-011.00e+000.26218332
GO:0043565sequence-specific DNA binding6.05e-011.00e+000.12514365
GO:0008285negative regulation of cell proliferation6.07e-011.00e+000.117111367
GO:0007155cell adhesion6.24e-011.00e+000.05218384
GO:0008284positive regulation of cell proliferation6.31e-011.00e+000.02218392
GO:0046982protein heterodimerization activity6.38e-011.00e+00-0.003111399
GO:0006508proteolysis6.48e-011.00e+00-0.04319410
GO:0006366transcription from RNA polymerase II promoter6.61e-011.00e+00-0.094112425
GO:0007596blood coagulation6.94e-011.00e+00-0.221114464
GO:0008270zinc ion binding7.59e-011.00e+00-0.4222121067
GO:0006351transcription, DNA-templated7.74e-011.00e+00-0.4083251585
GO:0042803protein homodimerization activity7.94e-011.00e+00-0.632111617
GO:0005789endoplasmic reticulum membrane8.04e-011.00e+00-0.676110636
GO:0045944positive regulation of transcription from RNA polymerase II promoter8.77e-011.00e+00-1.027119811
GO:0007165signal transduction9.15e-011.00e+00-1.255117950
GO:0005615extracellular space9.27e-011.00e+00-1.3431171010
GO:0006355regulation of transcription, DNA-templated9.44e-011.00e+00-1.4721171104
GO:0003677DNA binding9.71e-011.00e+00-1.7631261351
GO:0005886plasma membrane1.00e+001.00e+00-2.8321382834