meta-int-snw-2821

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-55854 tai-screen-luciferase 4.880 1.80e-26 2.35e-04 4.05e-04 5 3
int-snw-2821 tai-screen-luciferase 7.189 1.73e-180 9.22e-10 1.81e-04 17 15
reg-snw-60 tai-screen-luciferase 4.243 1.88e-19 3.43e-03 4.71e-03 12 5
reg-snw-1964 tai-screen-luciferase 4.532 1.75e-22 1.10e-03 1.69e-03 7 6
reg-snw-1121 tai-screen-luciferase 4.707 1.91e-24 5.19e-04 8.44e-04 5 3
reg-snw-1500 tai-screen-luciferase 4.226 2.77e-19 3.65e-03 4.98e-03 9 7
reg-snw-821 tai-screen-luciferase 4.344 1.76e-20 2.34e-03 3.35e-03 11 4
reg-snw-51164 tai-screen-luciferase 4.586 4.41e-23 8.78e-04 1.37e-03 6 4
reg-snw-57120 tai-screen-luciferase 4.450 1.33e-21 1.54e-03 2.29e-03 12 6
tai-screen-luciferase-meta-int-snw-2821 subnetwork

Genes (49)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 33-5.5457.555234--
CHMP2A 27243 33-9.0377.55541YesYes
RPS2 6187 16-3.2414.22613Yes-
DMD 1756 15-4.3384.24353--
COPA 1314 48-9.3955.672340YesYes
PAFAH1B1 5048 18-2.5834.58655Yes-
TNFRSF8 943 19-4.1064.45015--
EIF1AX 1964 14-3.0054.53243Yes-
CUL4B 8450 21-2.8095.269142--
HSF1 3297 46-4.1795.027209-Yes
ARFGEF1 10565 13-2.7224.34415--
CANX 821 17-1.9594.50465--
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RB1 5925 21-2.0854.707351--
EIF2S2 8894 31-4.3205.672103Yes-
ZC3H15 55854 143.2694.88011--
RPS16 6217 38-5.4444.880205--
CHM 1121 13-0.4834.7072--
CDC42 998 44-6.9604.707276YesYes
RPS11 6205 44-6.5887.555175Yes-
DCTN4 51164 13-1.8824.58619--
RPS6 6194 44-5.6038.046217Yes-
MRPS12 6183 35-5.4215.516341Yes-
RAN 5901 38-3.8094.325258YesYes
SERBP1 26135 35-4.6125.516106-Yes
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
HES4 57801 19-4.1534.45010--
GOPC 57120 191.7494.45068--
CAPRIN1 4076 14-2.2264.68842--
RPS24 6229 46-7.0348.389217Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS3A 6189 19-4.6477.189166Yes-
RPS4X 6191 44-6.7477.555263Yes-
PES1 23481 162.9174.22691--
DNAJC10 54431 13-2.3494.34411--
COPZ1 22818 48-8.3019.06313YesYes
YEATS4 8089 14-4.4444.53218YesYes
WDR46 9277 31-4.2904.226101YesYes
EIF2S3 1968 14-3.1444.53213Yes-
RPS27A 6233 45-5.6318.389344Yes-
EIF3M 10480 184.4514.88055Yes-
SRF 6722 151.9944.24323--
ACTB 60 15-1.7164.24323--
CTNND1 1500 16-2.6514.22653Yes-
GPI 2821 10-4.1307.18957--
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes

Interactions (150)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
TNFRSF8 943 RB1 5925 pd < reg.pazar.txt: no annot
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
EIF2S2 8894 PES1 23481 pp -- int.I2D: YeastLow
PAFAH1B1 5048 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
ACTB 60 RPS4X 6191 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 CANX 821 pd < reg.ITFP.txt: no annot
COPA 1314 RB1 5925 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pp -- int.Yu: muscle
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
COPA 1314 DCTN4 51164 pd > reg.ITFP.txt: no annot
CDC5L 988 CUL4B 8450 pd <> reg.ITFP.txt: no annot
RPS2 6187 RPS4X 6191 pp -- int.I2D: YeastHigh, YeastMedium, INTEROLOG
ACTB 60 RPS8 6202 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS9 6203 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RB1 5925 GOPC 57120 pd > reg.ITFP.txt: no annot
CANX 821 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
CANX 821 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
RB1 5925 HES4 57801 pd > reg.pazar.txt: no annot
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS13 6207 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 RPS11 6205 pp -- int.I2D: YeastMedium
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
CHM 1121 COPA 1314 pd < reg.ITFP.txt: no annot
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 EIF2S3 1968 pd > reg.ITFP.txt: no annot
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RB1 5925 SERBP1 26135 pd > reg.pazar.txt: no annot
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ACTB 60 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
MRPS12 6183 RPS2 6187 pp -- int.I2D: YeastMedium
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 ARFGEF1 10565 pp -- int.I2D: IntAct_Yeast
GPI 2821 RPS13 6207 pp -- int.I2D: IntAct_Yeast
ACTB 60 RPS24 6229 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS13 6207 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
GPI 2821 RPS27A 6233 pp -- int.I2D: Krogan_NonCore
RPS4X 6191 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS2 6187 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 ARFGEF1 10565 pp -- int.I2D: YeastLow
RPS3A 6189 RPS9 6203 pp -- int.I2D: IntAct
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 GOPC 57120 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 PES1 23481 pp -- int.I2D: IntAct_Yeast
PAFAH1B1 5048 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 GOPC 57120 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS2 6187 pp -- int.I2D: YeastMedium
CAPRIN1 4076 CKAP5 9793 pd < reg.ITFP.txt: no annot
RPS2 6187 RPS9 6203 pp -- int.I2D: BIND_Yeast
RPS24 6229 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ACTB 60 EIF3M 10480 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS3A 6189 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC42 998 ARFGEF1 10565 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
RPS2 6187 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CTNND1 1500 PES1 23481 pd <> reg.ITFP.txt: no annot
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
GPI 2821 RPS3A 6189 pp -- int.I2D: IntAct_Yeast
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 YEATS4 8089 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS9 6203 pp -- int.I2D: YeastMedium
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
ACTB 60 COPA 1314 pd < reg.ITFP.txt: no annot
ACTB 60 COPA 1314 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS13 6207 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
CAPRIN1 4076 CUL4B 8450 pd < reg.ITFP.txt: no annot
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS3A 6189 RPS4X 6191 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RPS2 6187 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 PES1 23481 pp -- int.I2D: IntAct_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RPS16 6217 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS2 6187 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
PAFAH1B1 5048 DCTN4 51164 pd > reg.ITFP.txt: no annot
DMD 1756 SRF 6722 pd < reg.pazar.txt: no annot;
reg.TRANSFAC.txt: no annot
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
CANX 821 RB1 5925 pd <> reg.ITFP.txt: no annot
RPS3A 6189 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
EIF2S3 1968 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
WDR46 9277 PES1 23481 pd <> reg.ITFP.txt: no annot
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RPS3A 6189 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PAFAH1B1 5048 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
CANX 821 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
ACTB 60 EIF1AX 1964 pp -- int.I2D: BioGrid_Yeast
CDC42 998 GOPC 57120 pp -- int.I2D: BioGrid
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
CANX 821 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
RPS2 6187 RPS11 6205 pp -- int.I2D: YeastMedium, INTEROLOG
ACTB 60 ARCN1 372 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 DNAJC10 54431 pd > reg.ITFP.txt: no annot
ACTB 60 YEATS4 8089 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
ACTB 60 RPS3A 6189 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RB1 5925 DCTN4 51164 pd > reg.ITFP.txt: no annot
COPA 1314 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 GOPC 57120 pd > reg.ITFP.txt: no annot
CTNND1 1500 RPS2 6187 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS16 6217 pp -- int.I2D: YeastMedium
RPS2 6187 RPS16 6217 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CUL4B 8450 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
CHM 1121 RB1 5925 pd < reg.ITFP.txt: no annot
RPS13 6207 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 RPS3A 6189 pp -- int.I2D: IntAct_Yeast
CANX 821 DCTN4 51164 pd > reg.ITFP.txt: no annot
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
EIF2S3 1968 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
EIF1AX 1964 EIF3M 10480 pd <> reg.ITFP.txt: no annot
CDC42 998 RB1 5925 pd < reg.pazar.txt: no annot
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
CANX 821 DNAJC10 54431 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
EIF3M 10480 ZC3H15 55854 pd > reg.ITFP.txt: no annot
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
ACTB 60 SRF 6722 pd < reg.pazar.txt: no annot;
reg.oreganno.txt: no annot
RAN 5901 PES1 23481 pd < reg.ITFP.txt: no annot
EIF2S3 1968 EIF2S2 8894 pp -- int.Intact: MI:0407(direct interaction);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Yu_GoldStd
RPS6 6194 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS27A 6233 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS6 6194 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 PAFAH1B1 5048 pd <> reg.ITFP.txt: no annot

Related GO terms (668)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006413translational initiation3.09e-225.05e-185.3461627131
GO:0022627cytosolic small ribosomal subunit4.59e-227.49e-186.679122139
GO:0019058viral life cycle1.81e-192.95e-155.3421425115
GO:0006412translation4.49e-187.32e-144.5031629235
GO:0019083viral transcription7.60e-181.24e-135.625122281
GO:0006415translational termination1.88e-173.07e-135.522122287
GO:0006414translational elongation4.37e-177.12e-135.426122293
GO:0003735structural constituent of ribosome1.71e-162.79e-124.9411324141
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.77e-162.89e-125.2641222104
GO:0044822poly(A) RNA binding4.76e-167.77e-122.89124421078
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay5.54e-169.04e-125.1321222114
GO:0005829cytosol6.37e-151.04e-102.05732742562
GO:0015935small ribosomal subunit2.67e-144.36e-107.1007917
GO:0044267cellular protein metabolic process3.14e-145.13e-103.5161729495
GO:0016020membrane2.43e-133.97e-092.31026481746
GO:0016071mRNA metabolic process1.86e-123.04e-084.1641229223
GO:0016070RNA metabolic process6.21e-121.01e-074.0161229247
GO:0016032viral process2.87e-114.68e-073.2101537540
GO:0010467gene expression5.04e-118.23e-072.9941636669
GO:0048205COPI coating of Golgi vesicle5.03e-088.20e-046.6794613
GO:0030126COPI vesicle coat5.03e-088.20e-046.6794613
GO:0005925focal adhesion1.19e-071.94e-033.1701023370
GO:0070062extracellular vesicular exosome1.86e-073.03e-031.60623512516
GO:0061024membrane organization2.49e-074.06e-033.997711146
GO:0036464cytoplasmic ribonucleoprotein granule5.04e-078.23e-035.9204522
GO:0006890retrograde vesicle-mediated transport, Golgi to ER8.66e-071.41e-025.7364625
GO:0005840ribosome8.77e-071.43e-024.81951059
GO:0030529ribonucleoprotein complex1.11e-061.82e-024.13268114
GO:0042274ribosomal small subunit biogenesis5.49e-068.96e-026.3803612
GO:0005515protein binding5.97e-069.74e-020.88634876127
GO:0003743translation initiation factor activity1.38e-052.24e-014.7654549
GO:0008135translation factor activity, nucleic acid binding4.92e-058.04e-015.3803424
GO:0005737cytoplasm4.94e-058.07e-011.06625653976
GO:0019843rRNA binding7.07e-051.00e+005.2103427
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.78e-051.00e+007.058235
GO:0033119negative regulation of RNA splicing8.78e-051.00e+007.058225
GO:0034332adherens junction organization1.69e-041.00e+004.7953436
GO:0007097nuclear migration1.84e-041.00e+006.572227
GO:0006364rRNA processing1.94e-041.00e+003.7954896
GO:0043234protein complex2.64e-041.00e+002.73669300
GO:0005730nucleolus3.05e-041.00e+001.46914361684
GO:0090136epithelial cell-cell adhesion3.14e-041.00e+006.210229
GO:0007067mitotic nuclear division6.25e-041.00e+002.85057231
GO:0035267NuA4 histone acetyltransferase complex7.85e-041.00e+005.5722214
GO:0048821erythrocyte development9.04e-041.00e+005.4732215
GO:0031369translation initiation factor binding9.04e-041.00e+005.4732215
GO:0050998nitric-oxide synthase binding1.03e-031.00e+005.3802316
GO:0075733intracellular transport of virus1.17e-031.00e+005.2922317
GO:0006891intra-Golgi vesicle-mediated transport1.17e-031.00e+005.2922317
GO:0017022myosin binding1.31e-031.00e+005.2102218
GO:0003729mRNA binding1.36e-031.00e+003.7753373
GO:0006886intracellular protein transport1.78e-031.00e+002.94546173
GO:0009306protein secretion1.79e-031.00e+004.9872221
GO:0005844polysome2.53e-031.00e+004.7362225
GO:0005200structural constituent of cytoskeleton2.73e-031.00e+003.4263693
GO:0030038contractile actin filament bundle assembly3.00e-031.00e+008.380111
GO:0045556positive regulation of TRAIL biosynthetic process3.00e-031.00e+008.380111
GO:0090287regulation of cellular response to growth factor stimulus3.00e-031.00e+008.380111
GO:0000235astral microtubule3.00e-031.00e+008.380111
GO:0004347glucose-6-phosphate isomerase activity3.00e-031.00e+008.380111
GO:0090284positive regulation of protein glycosylation in Golgi3.00e-031.00e+008.380111
GO:0019242methylglyoxal biosynthetic process3.00e-031.00e+008.380111
GO:0002183cytoplasmic translational initiation3.00e-031.00e+008.380111
GO:0090230regulation of centromere complex assembly3.00e-031.00e+008.380111
GO:0022605oogenesis stage3.00e-031.00e+008.380111
GO:0043004cytoplasmic sequestering of CFTR protein3.00e-031.00e+008.380111
GO:0021691cerebellar Purkinje cell layer maturation3.00e-031.00e+008.380111
GO:0051660establishment of centrosome localization3.00e-031.00e+008.380111
GO:0034975protein folding in endoplasmic reticulum3.00e-031.00e+008.380111
GO:0016866intramolecular transferase activity3.00e-031.00e+008.380111
GO:0046016positive regulation of transcription by glucose3.00e-031.00e+008.380111
GO:0046469platelet activating factor metabolic process3.00e-031.00e+008.380111
GO:0007093mitotic cell cycle checkpoint3.88e-031.00e+004.4262231
GO:0051219phosphoprotein binding4.14e-031.00e+004.3802432
GO:0007611learning or memory4.66e-031.00e+004.2922234
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway5.21e-031.00e+004.2102336
GO:0050681androgen receptor binding5.79e-031.00e+004.1322238
GO:0046185aldehyde catabolic process6.00e-031.00e+007.380112
GO:0010256endomembrane system organization6.00e-031.00e+007.380112
GO:0071987WD40-repeat domain binding6.00e-031.00e+007.380112
GO:0060661submandibular salivary gland formation6.00e-031.00e+007.380112
GO:0036035osteoclast development6.00e-031.00e+007.380112
GO:0014819regulation of skeletal muscle contraction6.00e-031.00e+007.380112
GO:0086001cardiac muscle cell action potential6.00e-031.00e+007.380112
GO:0071338positive regulation of hair follicle cell proliferation6.00e-031.00e+007.380112
GO:0051081nuclear envelope disassembly6.00e-031.00e+007.380112
GO:0002176male germ cell proliferation6.00e-031.00e+007.380112
GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)6.00e-031.00e+007.380112
GO:0072422signal transduction involved in DNA damage checkpoint6.00e-031.00e+007.380112
GO:0090135actin filament branching6.00e-031.00e+007.380112
GO:0031134sister chromatid biorientation6.00e-031.00e+007.380112
GO:0010736serum response element binding6.00e-031.00e+007.380112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis6.00e-031.00e+007.380112
GO:0021766hippocampus development6.10e-031.00e+004.0942339
GO:0030521androgen receptor signaling pathway6.72e-031.00e+004.0222341
GO:0034613cellular protein localization7.71e-031.00e+003.9202244
GO:0000086G2/M transition of mitotic cell cycle8.04e-031.00e+002.86736137
GO:0021762substantia nigra development8.40e-031.00e+003.8562246
GO:0008344adult locomotory behavior8.76e-031.00e+003.8252247
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding8.98e-031.00e+006.795113
GO:0014809regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion8.98e-031.00e+006.795113
GO:0060947cardiac vascular smooth muscle cell differentiation8.98e-031.00e+006.795113
GO:0003161cardiac conduction system development8.98e-031.00e+006.795113
GO:0071459protein localization to chromosome, centromeric region8.98e-031.00e+006.795113
GO:1900222negative regulation of beta-amyloid clearance8.98e-031.00e+006.795113
GO:1901385regulation of voltage-gated calcium channel activity8.98e-031.00e+006.795113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle8.98e-031.00e+006.795113
GO:0045505dynein intermediate chain binding8.98e-031.00e+006.795113
GO:0051683establishment of Golgi localization8.98e-031.00e+006.795123
GO:0070545PeBoW complex8.98e-031.00e+006.795113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb8.98e-031.00e+006.795113
GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.98e-031.00e+006.795113
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor8.98e-031.00e+006.795113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity8.98e-031.00e+006.795113
GO:0033561regulation of water loss via skin8.98e-031.00e+006.795113
GO:0005850eukaryotic translation initiation factor 2 complex8.98e-031.00e+006.795113
GO:0000056ribosomal small subunit export from nucleus8.98e-031.00e+006.795123
GO:0034663endoplasmic reticulum chaperone complex8.98e-031.00e+006.795113
GO:1902083negative regulation of peptidyl-cysteine S-nitrosylation8.98e-031.00e+006.795123
GO:0021540corpus callosum morphogenesis8.98e-031.00e+006.795113
GO:0030687preribosome, large subunit precursor8.98e-031.00e+006.795113
GO:0007030Golgi organization9.87e-031.00e+003.7362350
GO:0000082G1/S transition of mitotic cell cycle1.03e-021.00e+002.736311150
GO:0030175filopodium1.10e-021.00e+003.6522253
GO:0071922regulation of cohesin localization to chromatin1.20e-021.00e+006.380124
GO:0034191apolipoprotein A-I receptor binding1.20e-021.00e+006.380114
GO:0007000nucleolus organization1.20e-021.00e+006.380124
GO:0010669epithelial structure maintenance1.20e-021.00e+006.380114
GO:0060684epithelial-mesenchymal cell signaling1.20e-021.00e+006.380114
GO:0051835positive regulation of synapse structural plasticity1.20e-021.00e+006.380114
GO:0015036disulfide oxidoreductase activity1.20e-021.00e+006.380114
GO:0043550regulation of lipid kinase activity1.20e-021.00e+006.380114
GO:0016013syntrophin complex1.20e-021.00e+006.380124
GO:0090231regulation of spindle checkpoint1.20e-021.00e+006.380114
GO:0072384organelle transport along microtubule1.20e-021.00e+006.380124
GO:0003257positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation1.20e-021.00e+006.380114
GO:0048664neuron fate determination1.20e-021.00e+006.380114
GO:0010735positive regulation of transcription via serum response element binding1.20e-021.00e+006.380114
GO:0005968Rab-protein geranylgeranyltransferase complex1.20e-021.00e+006.380114
GO:0000055ribosomal large subunit export from nucleus1.20e-021.00e+006.380114
GO:0035189Rb-E2F complex1.20e-021.00e+006.380114
GO:0034088maintenance of mitotic sister chromatid cohesion1.20e-021.00e+006.380114
GO:0034349glial cell apoptotic process1.20e-021.00e+006.380114
GO:0016197endosomal transport1.31e-021.00e+003.5222358
GO:0045216cell-cell junction organization1.35e-021.00e+003.4972259
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.40e-021.00e+002.57234168
GO:0036336dendritic cell migration1.49e-021.00e+006.058115
GO:2000651positive regulation of sodium ion transmembrane transporter activity1.49e-021.00e+006.058115
GO:0035088establishment or maintenance of apical/basal cell polarity1.49e-021.00e+006.058115
GO:0048667cell morphogenesis involved in neuron differentiation1.49e-021.00e+006.058115
GO:1902188positive regulation of viral release from host cell1.49e-021.00e+006.058115
GO:0031256leading edge membrane1.49e-021.00e+006.058115
GO:0044233ER-mitochondrion membrane contact site1.49e-021.00e+006.058115
GO:0035912dorsal aorta morphogenesis1.49e-021.00e+006.058115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.49e-021.00e+006.058115
GO:0043043peptide biosynthetic process1.49e-021.00e+006.058115
GO:0031023microtubule organizing center organization1.49e-021.00e+006.058115
GO:0030424axon1.49e-021.00e+002.53834172
GO:0004663Rab geranylgeranyltransferase activity1.49e-021.00e+006.058115
GO:0019901protein kinase binding1.54e-021.00e+002.05849320
GO:0043353enucleate erythrocyte differentiation1.79e-021.00e+005.795116
GO:0007143female meiotic division1.79e-021.00e+005.795116
GO:0044458motile cilium assembly1.79e-021.00e+005.795116
GO:0002309T cell proliferation involved in immune response1.79e-021.00e+005.795116
GO:0045182translation regulator activity1.79e-021.00e+005.795126
GO:0051150regulation of smooth muscle cell differentiation1.79e-021.00e+005.795116
GO:0018344protein geranylgeranylation1.79e-021.00e+005.795116
GO:0060789hair follicle placode formation1.79e-021.00e+005.795116
GO:0008090retrograde axon cargo transport1.79e-021.00e+005.795116
GO:0051347positive regulation of transferase activity1.79e-021.00e+005.795116
GO:0048554positive regulation of metalloenzyme activity1.79e-021.00e+005.795116
GO:0048029monosaccharide binding1.79e-021.00e+005.795116
GO:0050792regulation of viral process1.79e-021.00e+005.795116
GO:0002181cytoplasmic translation1.79e-021.00e+005.795126
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.79e-021.00e+005.795116
GO:0001667ameboidal-type cell migration1.79e-021.00e+005.795116
GO:0000974Prp19 complex1.79e-021.00e+005.795116
GO:0030957Tat protein binding1.79e-021.00e+005.795116
GO:0034452dynactin binding1.79e-021.00e+005.795116
GO:0006924activation-induced cell death of T cells1.79e-021.00e+005.795126
GO:0034329cell junction assembly1.92e-021.00e+003.2302271
GO:0000785chromatin2.03e-021.00e+003.1902273
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoter2.08e-021.00e+005.572117
GO:0006893Golgi to plasma membrane transport2.08e-021.00e+005.572117
GO:0060055angiogenesis involved in wound healing2.08e-021.00e+005.572117
GO:0060136embryonic process involved in female pregnancy2.08e-021.00e+005.572117
GO:0043497regulation of protein heterodimerization activity2.08e-021.00e+005.572117
GO:0050658RNA transport2.08e-021.00e+005.572117
GO:0003334keratinocyte development2.08e-021.00e+005.572117
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.08e-021.00e+005.572117
GO:0070914UV-damage excision repair2.08e-021.00e+005.572117
GO:0001961positive regulation of cytokine-mediated signaling pathway2.08e-021.00e+005.572117
GO:0000028ribosomal small subunit assembly2.08e-021.00e+005.572137
GO:0034101erythrocyte homeostasis2.08e-021.00e+005.572117
GO:0002162dystroglycan binding2.08e-021.00e+005.572117
GO:0030157pancreatic juice secretion2.08e-021.00e+005.572117
GO:0071541eukaryotic translation initiation factor 3 complex, eIF3m2.08e-021.00e+005.572117
GO:0017145stem cell division2.08e-021.00e+005.572117
GO:0000930gamma-tubulin complex2.08e-021.00e+005.572117
GO:0034259negative regulation of Rho GTPase activity2.08e-021.00e+005.572117
GO:0031175neuron projection development2.13e-021.00e+003.1512275
GO:0003723RNA binding2.16e-021.00e+001.908410355
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.24e-021.00e+003.1132477
GO:0003924GTPase activity2.30e-021.00e+002.29936203
GO:0051156glucose 6-phosphate metabolic process2.38e-021.00e+005.380118
GO:0090009primitive streak formation2.38e-021.00e+005.380118
GO:0031512motile primary cilium2.38e-021.00e+005.380118
GO:0039702viral budding via host ESCRT complex2.38e-021.00e+005.380118
GO:0043589skin morphogenesis2.38e-021.00e+005.380118
GO:0007289spermatid nucleus differentiation2.38e-021.00e+005.380118
GO:0070688MLL5-L complex2.38e-021.00e+005.380118
GO:0005869dynactin complex2.38e-021.00e+005.380118
GO:0051489regulation of filopodium assembly2.38e-021.00e+005.380118
GO:0061003positive regulation of dendritic spine morphogenesis2.38e-021.00e+005.380118
GO:0043197dendritic spine2.57e-021.00e+003.0052283
GO:0097284hepatocyte apoptotic process2.67e-021.00e+005.210119
GO:0000983RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity2.67e-021.00e+005.210119
GO:0000075cell cycle checkpoint2.67e-021.00e+005.210119
GO:0021895cerebral cortex neuron differentiation2.67e-021.00e+005.210119
GO:0005915zonula adherens2.67e-021.00e+005.210119
GO:0030837negative regulation of actin filament polymerization2.67e-021.00e+005.210119
GO:0032319regulation of Rho GTPase activity2.67e-021.00e+005.210119
GO:0045059positive thymic T cell selection2.67e-021.00e+005.210119
GO:0007599hemostasis2.67e-021.00e+005.210119
GO:0006184GTP catabolic process2.83e-021.00e+002.18336220
GO:0034237protein kinase A regulatory subunit binding2.96e-021.00e+005.0581110
GO:0051787misfolded protein binding2.96e-021.00e+005.0581110
GO:0042535positive regulation of tumor necrosis factor biosynthetic process2.96e-021.00e+005.0581110
GO:0031274positive regulation of pseudopodium assembly2.96e-021.00e+005.0581210
GO:0001076RNA polymerase II transcription factor binding transcription factor activity2.96e-021.00e+005.0581110
GO:0090303positive regulation of wound healing2.96e-021.00e+005.0581110
GO:0061029eyelid development in camera-type eye2.96e-021.00e+005.0581110
GO:0001675acrosome assembly2.96e-021.00e+005.0581110
GO:0060218hematopoietic stem cell differentiation2.96e-021.00e+005.0581110
GO:0060047heart contraction2.96e-021.00e+005.0581110
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II3.11e-021.00e+002.8562392
GO:0016363nuclear matrix3.11e-021.00e+002.8562492
GO:0042470melanosome3.11e-021.00e+002.8562292
GO:0000278mitotic cell cycle3.12e-021.00e+001.743416398
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.24e-021.00e+002.8252794
GO:0045502dynein binding3.25e-021.00e+004.9201111
GO:0045176apical protein localization3.25e-021.00e+004.9201111
GO:0017166vinculin binding3.25e-021.00e+004.9201111
GO:0042551neuron maturation3.25e-021.00e+004.9201111
GO:0045651positive regulation of macrophage differentiation3.25e-021.00e+004.9201111
GO:0045120pronucleus3.25e-021.00e+004.9201111
GO:0035518histone H2A monoubiquitination3.25e-021.00e+004.9201211
GO:0002011morphogenesis of an epithelial sheet3.25e-021.00e+004.9201111
GO:0021819layer formation in cerebral cortex3.25e-021.00e+004.9201111
GO:0005634nucleus3.28e-021.00e+000.53521664828
GO:0001764neuron migration3.37e-021.00e+002.7952296
GO:0030426growth cone3.43e-021.00e+002.7802397
GO:0030425dendrite3.52e-021.00e+002.05833240
GO:0007051spindle organization3.54e-021.00e+004.7951112
GO:0051146striated muscle cell differentiation3.54e-021.00e+004.7951212
GO:0043149stress fiber assembly3.54e-021.00e+004.7951212
GO:0019082viral protein processing3.54e-021.00e+004.7951212
GO:0030140trans-Golgi network transport vesicle3.54e-021.00e+004.7951112
GO:0043968histone H2A acetylation3.54e-021.00e+004.7951112
GO:0072583clathrin-mediated endocytosis3.54e-021.00e+004.7951112
GO:0047496vesicle transport along microtubule3.54e-021.00e+004.7951112
GO:1903543positive regulation of exosomal secretion3.54e-021.00e+004.7951112
GO:0055003cardiac myofibril assembly3.54e-021.00e+004.7951112
GO:0008134transcription factor binding3.75e-021.00e+002.02235246
GO:0042789mRNA transcription from RNA polymerase II promoter3.83e-021.00e+004.6791113
GO:0001671ATPase activator activity3.83e-021.00e+004.6791113
GO:0043488regulation of mRNA stability3.83e-021.00e+004.6791113
GO:0033290eukaryotic 48S preinitiation complex3.83e-021.00e+004.6791113
GO:0042273ribosomal large subunit biogenesis3.83e-021.00e+004.6791113
GO:0031929TOR signaling3.83e-021.00e+004.6791113
GO:0032479regulation of type I interferon production3.83e-021.00e+004.6791213
GO:0005662DNA replication factor A complex3.83e-021.00e+004.6791113
GO:1900087positive regulation of G1/S transition of mitotic cell cycle3.83e-021.00e+004.6791113
GO:0060314regulation of ryanodine-sensitive calcium-release channel activity3.83e-021.00e+004.6791113
GO:0035855megakaryocyte development3.83e-021.00e+004.6791113
GO:0014069postsynaptic density4.03e-021.00e+002.65223106
GO:0043025neuronal cell body4.06e-021.00e+001.97635254
GO:0035371microtubule plus-end4.12e-021.00e+004.5721114
GO:0031333negative regulation of protein complex assembly4.12e-021.00e+004.5721114
GO:0016282eukaryotic 43S preinitiation complex4.12e-021.00e+004.5721114
GO:0060292long term synaptic depression4.12e-021.00e+004.5721114
GO:0048488synaptic vesicle endocytosis4.12e-021.00e+004.5721114
GO:0031996thioesterase binding4.12e-021.00e+004.5721114
GO:0034185apolipoprotein binding4.12e-021.00e+004.5721114
GO:0030496midbody4.24e-021.00e+002.61224109
GO:0005654nucleoplasm4.38e-021.00e+001.0907261095
GO:0030131clathrin adaptor complex4.41e-021.00e+004.4731115
GO:0002042cell migration involved in sprouting angiogenesis4.41e-021.00e+004.4731115
GO:0030225macrophage differentiation4.41e-021.00e+004.4731115
GO:0016514SWI/SNF complex4.41e-021.00e+004.4731115
GO:0045987positive regulation of smooth muscle contraction4.41e-021.00e+004.4731115
GO:0045445myoblast differentiation4.41e-021.00e+004.4731115
GO:0005852eukaryotic translation initiation factor 3 complex4.41e-021.00e+004.4731115
GO:0016010dystrophin-associated glycoprotein complex4.41e-021.00e+004.4731115
GO:2000114regulation of establishment of cell polarity4.41e-021.00e+004.4731115
GO:0051233spindle midzone4.41e-021.00e+004.4731215
GO:0048854brain morphogenesis4.41e-021.00e+004.4731115
GO:0060347heart trabecula formation4.41e-021.00e+004.4731115
GO:0032839dendrite cytoplasm4.70e-021.00e+004.3801116
GO:0007405neuroblast proliferation4.70e-021.00e+004.3801116
GO:0032012regulation of ARF protein signal transduction4.70e-021.00e+004.3801116
GO:0019226transmission of nerve impulse4.70e-021.00e+004.3801116
GO:0000132establishment of mitotic spindle orientation4.70e-021.00e+004.3801216
GO:0042176regulation of protein catabolic process4.70e-021.00e+004.3801416
GO:0033137negative regulation of peptidyl-serine phosphorylation4.70e-021.00e+004.3801116
GO:0030220platelet formation4.70e-021.00e+004.3801116
GO:0043623cellular protein complex assembly4.70e-021.00e+004.3801116
GO:0046716muscle cell cellular homeostasis4.70e-021.00e+004.3801116
GO:0050775positive regulation of dendrite morphogenesis4.70e-021.00e+004.3801116
GO:0043065positive regulation of apoptotic process4.90e-021.00e+001.86736274
GO:0006006glucose metabolic process4.96e-021.00e+002.48524119
GO:0035255ionotropic glutamate receptor binding4.99e-021.00e+004.2921117
GO:0010880regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum4.99e-021.00e+004.2921117
GO:0033365protein localization to organelle4.99e-021.00e+004.2921117
GO:0043274phospholipase binding4.99e-021.00e+004.2921117
GO:0019068virion assembly4.99e-021.00e+004.2921217
GO:0008306associative learning4.99e-021.00e+004.2921117
GO:0031527filopodium membrane4.99e-021.00e+004.2921117
GO:0001829trophectodermal cell differentiation4.99e-021.00e+004.2921117
GO:0030742GTP-dependent protein binding4.99e-021.00e+004.2921117
GO:0001731formation of translation preinitiation complex4.99e-021.00e+004.2921117
GO:0006612protein targeting to membrane5.27e-021.00e+004.2101218
GO:0045773positive regulation of axon extension5.27e-021.00e+004.2101118
GO:0005086ARF guanyl-nucleotide exchange factor activity5.27e-021.00e+004.2101118
GO:0006325chromatin organization5.27e-021.00e+002.43722123
GO:0090316positive regulation of intracellular protein transport5.27e-021.00e+004.2101118
GO:0030532small nuclear ribonucleoprotein complex5.27e-021.00e+004.2101118
GO:0006259DNA metabolic process5.56e-021.00e+004.1321119
GO:0007088regulation of mitosis5.56e-021.00e+004.1321119
GO:0017134fibroblast growth factor binding5.56e-021.00e+004.1321219
GO:0010881regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion5.56e-021.00e+004.1321119
GO:0030036actin cytoskeleton organization5.73e-021.00e+002.36923129
GO:2000134negative regulation of G1/S transition of mitotic cell cycle5.84e-021.00e+004.0581120
GO:0090398cellular senescence5.84e-021.00e+004.0581120
GO:0030544Hsp70 protein binding5.84e-021.00e+004.0581120
GO:0043473pigmentation5.84e-021.00e+004.0581220
GO:0000790nuclear chromatin6.05e-021.00e+002.32422133
GO:0043021ribonucleoprotein complex binding6.12e-021.00e+003.9871121
GO:0007369gastrulation6.12e-021.00e+003.9871121
GO:0015035protein disulfide oxidoreductase activity6.12e-021.00e+003.9871121
GO:0000793condensed chromosome6.12e-021.00e+003.9871221
GO:0043034costamere6.12e-021.00e+003.9871121
GO:0046847filopodium assembly6.12e-021.00e+003.9871121
GO:0007220Notch receptor processing6.40e-021.00e+003.9201222
GO:0005790smooth endoplasmic reticulum6.40e-021.00e+003.9201122
GO:0031435mitogen-activated protein kinase kinase kinase binding6.40e-021.00e+003.9201122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle6.40e-021.00e+003.9201122
GO:0030863cortical cytoskeleton6.40e-021.00e+003.9201122
GO:0007052mitotic spindle organization6.40e-021.00e+003.9201122
GO:1900026positive regulation of substrate adhesion-dependent cell spreading6.69e-021.00e+003.8561123
GO:0051491positive regulation of filopodium assembly6.69e-021.00e+003.8561223
GO:0002040sprouting angiogenesis6.69e-021.00e+003.8561123
GO:0045879negative regulation of smoothened signaling pathway6.69e-021.00e+003.8561123
GO:0051017actin filament bundle assembly6.69e-021.00e+003.8561123
GO:0008060ARF GTPase activator activity6.69e-021.00e+003.8561123
GO:0001892embryonic placenta development6.69e-021.00e+003.8561123
GO:0051297centrosome organization6.69e-021.00e+003.8561223
GO:0043044ATP-dependent chromatin remodeling6.69e-021.00e+003.8561123
GO:0005911cell-cell junction6.78e-021.00e+002.23022142
GO:0005761mitochondrial ribosome6.97e-021.00e+003.7951124
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress6.97e-021.00e+003.7951124
GO:0007163establishment or maintenance of cell polarity6.97e-021.00e+003.7951224
GO:0046329negative regulation of JNK cascade6.97e-021.00e+003.7951124
GO:0048471perinuclear region of cytoplasm7.13e-021.00e+001.34949523
GO:0006611protein export from nucleus7.25e-021.00e+003.7361125
GO:0032781positive regulation of ATPase activity7.25e-021.00e+003.7361125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway7.25e-021.00e+003.7361225
GO:0045296cadherin binding7.25e-021.00e+003.7361125
GO:0006457protein folding7.37e-021.00e+002.16123149
GO:0045931positive regulation of mitotic cell cycle7.53e-021.00e+003.6791226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia7.53e-021.00e+003.6791226
GO:0045214sarcomere organization7.53e-021.00e+003.6791126
GO:0045859regulation of protein kinase activity7.53e-021.00e+003.6791126
GO:0005978glycogen biosynthetic process7.53e-021.00e+003.6791226
GO:0048589developmental growth7.53e-021.00e+003.6791126
GO:0001707mesoderm formation7.53e-021.00e+003.6791126
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity7.53e-021.00e+003.6791226
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane7.53e-021.00e+003.6791126
GO:0042981regulation of apoptotic process7.54e-021.00e+002.14127151
GO:0005525GTP binding7.54e-021.00e+001.60736328
GO:0051149positive regulation of muscle cell differentiation7.80e-021.00e+003.6251227
GO:0032720negative regulation of tumor necrosis factor production7.80e-021.00e+003.6251127
GO:0007616long-term memory7.80e-021.00e+003.6251127
GO:0005083small GTPase regulator activity7.80e-021.00e+003.6251127
GO:0031424keratinization7.80e-021.00e+003.6251127
GO:0045184establishment of protein localization7.80e-021.00e+003.6251227
GO:0048565digestive tract development7.80e-021.00e+003.6251127
GO:0031069hair follicle morphogenesis7.80e-021.00e+003.6251127
GO:0003682chromatin binding7.86e-021.00e+001.58134334
GO:0005788endoplasmic reticulum lumen8.06e-021.00e+002.08522157
GO:0032467positive regulation of cytokinesis8.08e-021.00e+003.5721128
GO:0043967histone H4 acetylation8.08e-021.00e+003.5721228
GO:0031492nucleosomal DNA binding8.08e-021.00e+003.5721128
GO:0019894kinesin binding8.08e-021.00e+003.5721128
GO:0005875microtubule associated complex8.08e-021.00e+003.5721128
GO:0045597positive regulation of cell differentiation8.08e-021.00e+003.5721128
GO:0007017microtubule-based process8.08e-021.00e+003.5721228
GO:0005813centrosome8.14e-021.00e+001.56039339
GO:0005198structural molecule activity8.24e-021.00e+002.06725159
GO:0031252cell leading edge8.36e-021.00e+003.5221329
GO:0003730mRNA 3'-UTR binding8.36e-021.00e+003.5221129
GO:0034605cellular response to heat8.36e-021.00e+003.5221129
GO:0072686mitotic spindle8.36e-021.00e+003.5221129
GO:0043005neuron projection8.42e-021.00e+002.04926161
GO:0010977negative regulation of neuron projection development8.63e-021.00e+003.4731230
GO:0007346regulation of mitotic cell cycle8.63e-021.00e+003.4731330
GO:0031647regulation of protein stability8.63e-021.00e+003.4731130
GO:0002027regulation of heart rate8.63e-021.00e+003.4731230
GO:0040018positive regulation of multicellular organism growth8.63e-021.00e+003.4731130
GO:0010494cytoplasmic stress granule8.63e-021.00e+003.4731230
GO:0061077chaperone-mediated protein folding8.91e-021.00e+003.4261131
GO:0015031protein transport9.17e-021.00e+001.48534357
GO:0032480negative regulation of type I interferon production9.18e-021.00e+003.3801232
GO:0070830tight junction assembly9.45e-021.00e+003.3351133
GO:0033077T cell differentiation in thymus9.45e-021.00e+003.3351133
GO:0001569patterning of blood vessels9.73e-021.00e+003.2921134
GO:0001890placenta development9.73e-021.00e+003.2921134
GO:0042692muscle cell differentiation9.73e-021.00e+003.2921234
GO:0008285negative regulation of cell proliferation9.76e-021.00e+001.44533367
GO:0045211postsynaptic membrane9.88e-021.00e+001.91223177
GO:0048666neuron development1.00e-011.00e+003.2501135
GO:0071333cellular response to glucose stimulus1.00e-011.00e+003.2501235
GO:0009725response to hormone1.00e-011.00e+003.2501135
GO:0031625ubiquitin protein ligase binding1.02e-011.00e+001.88824180
GO:0051402neuron apoptotic process1.03e-011.00e+003.2101136
GO:0019904protein domain specific binding1.03e-011.00e+001.88023181
GO:0030433ER-associated ubiquitin-dependent protein catabolic process1.03e-011.00e+003.2101136
GO:0006446regulation of translational initiation1.03e-011.00e+003.2101236
GO:0001895retina homeostasis1.03e-011.00e+003.2101136
GO:0001102RNA polymerase II activating transcription factor binding1.05e-011.00e+003.1701137
GO:0051084'de novo' posttranslational protein folding1.05e-011.00e+003.1701237
GO:0005791rough endoplasmic reticulum1.05e-011.00e+003.1701137
GO:0001568blood vessel development1.08e-011.00e+003.1321238
GO:0070527platelet aggregation1.08e-011.00e+003.1321138
GO:0030049muscle filament sliding1.08e-011.00e+003.1321238
GO:0045740positive regulation of DNA replication1.08e-011.00e+003.1321138
GO:0006096glycolytic process1.11e-011.00e+003.0941139
GO:0043547positive regulation of GTPase activity1.11e-011.00e+001.81024190
GO:0032092positive regulation of protein binding1.11e-011.00e+003.0941139
GO:0031490chromatin DNA binding1.11e-011.00e+003.0941139
GO:0060048cardiac muscle contraction1.11e-011.00e+003.0941139
GO:0001933negative regulation of protein phosphorylation1.11e-011.00e+003.0941139
GO:0007173epidermal growth factor receptor signaling pathway1.12e-011.00e+001.80225191
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.13e-011.00e+003.0581140
GO:0051117ATPase binding1.16e-011.00e+003.0221241
GO:0008307structural constituent of muscle1.16e-011.00e+003.0221141
GO:0017148negative regulation of translation1.16e-011.00e+003.0221141
GO:0050885neuromuscular process controlling balance1.16e-011.00e+003.0221141
GO:0007249I-kappaB kinase/NF-kappaB signaling1.16e-011.00e+003.0221441
GO:0021987cerebral cortex development1.19e-011.00e+002.9871142
GO:0030155regulation of cell adhesion1.19e-011.00e+002.9871142
GO:0035914skeletal muscle cell differentiation1.19e-011.00e+002.9871142
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway1.21e-011.00e+002.9531243
GO:0007286spermatid development1.24e-011.00e+002.9201144
GO:0005871kinesin complex1.24e-011.00e+002.9201144
GO:0000139Golgi membrane1.24e-011.00e+001.29237408
GO:0050896response to stimulus1.24e-011.00e+002.9201144
GO:0006094gluconeogenesis1.27e-011.00e+002.8881145
GO:0016328lateral plasma membrane1.29e-011.00e+002.8561346
GO:0044297cell body1.29e-011.00e+002.8561146
GO:0043525positive regulation of neuron apoptotic process1.29e-011.00e+002.8561246
GO:0045727positive regulation of translation1.29e-011.00e+002.8561146
GO:0001047core promoter binding1.29e-011.00e+002.8561146
GO:0019003GDP binding1.35e-011.00e+002.7951148
GO:0001947heart looping1.37e-011.00e+002.7651149
GO:0034097response to cytokine1.40e-011.00e+002.7361150
GO:0043066negative regulation of apoptotic process1.40e-011.00e+001.206314433
GO:0001948glycoprotein binding1.40e-011.00e+002.7361250
GO:0040008regulation of growth1.42e-011.00e+002.7071151
GO:0007254JNK cascade1.42e-011.00e+002.7071351
GO:0003684damaged DNA binding1.42e-011.00e+002.7071251
GO:0045732positive regulation of protein catabolic process1.42e-011.00e+002.7071151
GO:0045454cell redox homeostasis1.45e-011.00e+002.6791152
GO:0006959humoral immune response1.45e-011.00e+002.6791152
GO:0034976response to endoplasmic reticulum stress1.45e-011.00e+002.6791152
GO:0016042lipid catabolic process1.45e-011.00e+002.6791252
GO:0006952defense response1.48e-011.00e+002.6521153
GO:0030666endocytic vesicle membrane1.50e-011.00e+002.6251254
GO:0051403stress-activated MAPK cascade1.50e-011.00e+002.6251454
GO:0019900kinase binding1.50e-011.00e+002.6251354
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.50e-011.00e+002.6251154
GO:0050680negative regulation of epithelial cell proliferation1.50e-011.00e+002.6251154
GO:0019221cytokine-mediated signaling pathway1.52e-011.00e+001.53425230
GO:0000226microtubule cytoskeleton organization1.53e-011.00e+002.5981155
GO:0046330positive regulation of JNK cascade1.53e-011.00e+002.5981155
GO:0006888ER to Golgi vesicle-mediated transport1.53e-011.00e+002.5981155
GO:0000932cytoplasmic mRNA processing body1.55e-011.00e+002.5721156
GO:0003713transcription coactivator activity1.61e-011.00e+001.47926239
GO:0051087chaperone binding1.63e-011.00e+002.4971159
GO:0005643nuclear pore1.63e-011.00e+002.4971159
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.63e-011.00e+002.4971159
GO:0010976positive regulation of neuron projection development1.65e-011.00e+002.4731260
GO:0032481positive regulation of type I interferon production1.68e-011.00e+002.4491361
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity1.68e-011.00e+002.4491161
GO:0033138positive regulation of peptidyl-serine phosphorylation1.68e-011.00e+002.4491161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.70e-011.00e+002.4261162
GO:0000776kinetochore1.73e-011.00e+002.4021363
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process1.73e-011.00e+002.4021263
GO:0006417regulation of translation1.73e-011.00e+002.4021463
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.75e-011.00e+002.3801264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.78e-011.00e+002.3571665
GO:0034146toll-like receptor 5 signaling pathway1.78e-011.00e+002.3571565
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.78e-011.00e+002.3571665
GO:0034166toll-like receptor 10 signaling pathway1.78e-011.00e+002.3571565
GO:0006469negative regulation of protein kinase activity1.78e-011.00e+002.3571165
GO:0045893positive regulation of transcription, DNA-templated1.79e-011.00e+001.03738487
GO:0071260cellular response to mechanical stimulus1.80e-011.00e+002.3351366
GO:0009636response to toxic substance1.80e-011.00e+002.3351166
GO:0031295T cell costimulation1.83e-011.00e+002.3141367
GO:0030141secretory granule1.83e-011.00e+002.3141267
GO:0006338chromatin remodeling1.85e-011.00e+002.2921268
GO:0045666positive regulation of neuron differentiation1.85e-011.00e+002.2921168
GO:0003700sequence-specific DNA binding transcription factor activity1.86e-011.00e+000.83349748
GO:0050790regulation of catalytic activity1.88e-011.00e+002.2711169
GO:0006887exocytosis1.88e-011.00e+002.2711169
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.90e-011.00e+002.2501870
GO:0035264multicellular organism growth1.90e-011.00e+002.2501170
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.93e-011.00e+002.2301571
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.93e-011.00e+002.2301571
GO:0042383sarcolemma1.93e-011.00e+002.2301271
GO:0006351transcription, DNA-templated1.94e-011.00e+000.5577171585
GO:0034162toll-like receptor 9 signaling pathway1.95e-011.00e+002.2101572
GO:0034134toll-like receptor 2 signaling pathway1.97e-011.00e+002.1901573
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.97e-011.00e+002.1901673
GO:0005975carbohydrate metabolic process1.99e-011.00e+001.28223274
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.00e-011.00e+002.1701874
GO:0005085guanyl-nucleotide exchange factor activity2.00e-011.00e+002.1701174
GO:0007265Ras protein signal transduction2.02e-011.00e+002.1511375
GO:0060070canonical Wnt signaling pathway2.02e-011.00e+002.1511275
GO:0035666TRIF-dependent toll-like receptor signaling pathway2.05e-011.00e+002.1321576
GO:0044325ion channel binding2.07e-011.00e+002.1131377
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.07e-011.00e+002.1131677
GO:0008584male gonad development2.07e-011.00e+002.1131177
GO:0002756MyD88-independent toll-like receptor signaling pathway2.09e-011.00e+002.0941578
GO:0017137Rab GTPase binding2.09e-011.00e+002.0941178
GO:0071013catalytic step 2 spliceosome2.12e-011.00e+002.0761179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process2.12e-011.00e+002.0761879
GO:0010629negative regulation of gene expression2.14e-011.00e+002.0581280
GO:0031902late endosome membrane2.14e-011.00e+002.0581180
GO:0002755MyD88-dependent toll-like receptor signaling pathway2.14e-011.00e+002.0581580
GO:0034138toll-like receptor 3 signaling pathway2.14e-011.00e+002.0581580
GO:0007264small GTPase mediated signal transduction2.16e-011.00e+001.20027290
GO:0045177apical part of cell2.19e-011.00e+002.0221182
GO:0030336negative regulation of cell migration2.21e-011.00e+002.0051283
GO:0007517muscle organ development2.21e-011.00e+002.0051183
GO:0005179hormone activity2.24e-011.00e+001.9871184
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.25e-011.00e+000.716411811
GO:0047485protein N-terminus binding2.28e-011.00e+001.9531186
GO:0007160cell-matrix adhesion2.33e-011.00e+001.9201188
GO:0050852T cell receptor signaling pathway2.33e-011.00e+001.9201288
GO:0090090negative regulation of canonical Wnt signaling pathway2.33e-011.00e+001.9201388
GO:0042593glucose homeostasis2.35e-011.00e+001.9041189
GO:0000187activation of MAPK activity2.38e-011.00e+001.8881390
GO:0000922spindle pole2.40e-011.00e+001.8721591
GO:0005856cytoskeleton2.40e-011.00e+001.09926311
GO:0018279protein N-linked glycosylation via asparagine2.40e-011.00e+001.8721191
GO:0016337single organismal cell-cell adhesion2.42e-011.00e+001.8561292
GO:0006928cellular component movement2.42e-011.00e+001.8561492
GO:0016605PML body2.42e-011.00e+001.8561292
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity2.45e-011.00e+001.8411193
GO:0001649osteoblast differentiation2.49e-011.00e+001.8101395
GO:0051082unfolded protein binding2.49e-011.00e+001.8101195
GO:0034142toll-like receptor 4 signaling pathway2.51e-011.00e+001.7951596
GO:0030154cell differentiation2.55e-011.00e+001.03523325
GO:0071456cellular response to hypoxia2.56e-011.00e+001.7651398
GO:0007411axon guidance2.57e-011.00e+001.02723327
GO:0051726regulation of cell cycle2.65e-011.00e+001.70712102
GO:0004888transmembrane signaling receptor activity2.67e-011.00e+001.69311103
GO:0005783endoplasmic reticulum2.77e-011.00e+000.71236610
GO:0005096GTPase activator activity2.78e-011.00e+001.62513108
GO:0002224toll-like receptor signaling pathway2.80e-011.00e+001.61215109
GO:0005938cell cortex2.80e-011.00e+001.61211109
GO:0045087innate immune response2.82e-011.00e+000.698311616
GO:0005815microtubule organizing center2.82e-011.00e+001.59814110
GO:0015630microtubule cytoskeleton2.87e-011.00e+001.57214112
GO:0030054cell junction2.90e-011.00e+000.90424356
GO:0005819spindle2.91e-011.00e+001.54714114
GO:0072562blood microparticle2.95e-011.00e+001.52211116
GO:0097190apoptotic signaling pathway2.95e-011.00e+001.52213116
GO:0000209protein polyubiquitination2.95e-011.00e+001.52217116
GO:0005802trans-Golgi network2.95e-011.00e+001.52212116
GO:0005635nuclear envelope2.95e-011.00e+001.52212116
GO:0043524negative regulation of neuron apoptotic process3.02e-011.00e+001.48511119
GO:0032496response to lipopolysaccharide3.08e-011.00e+001.44911122
GO:0016192vesicle-mediated transport3.08e-011.00e+001.44911122
GO:0051056regulation of small GTPase mediated signal transduction3.10e-011.00e+001.43713123
GO:0007568aging3.10e-011.00e+001.43712123
GO:0005794Golgi apparatus3.10e-011.00e+000.62038650
GO:0051092positive regulation of NF-kappaB transcription factor activity3.14e-011.00e+001.41413125
GO:0007219Notch signaling pathway3.14e-011.00e+001.41414125
GO:0007050cell cycle arrest3.16e-011.00e+001.40212126
GO:0006511ubiquitin-dependent protein catabolic process3.18e-011.00e+001.39113127
GO:0008201heparin binding3.18e-011.00e+001.39111127
GO:0030027lamellipodium3.25e-011.00e+001.35713130
GO:0007179transforming growth factor beta receptor signaling pathway3.25e-011.00e+001.35714130
GO:0046983protein dimerization activity3.27e-011.00e+001.34613131
GO:0008284positive regulation of cell proliferation3.30e-011.00e+000.76527392
GO:0045202synapse3.45e-011.00e+001.25011140
GO:0007507heart development3.47e-011.00e+001.24011141
GO:0016055Wnt signaling pathway3.47e-011.00e+001.24013141
GO:0008286insulin receptor signaling pathway3.53e-011.00e+001.21014144
GO:0008083growth factor activity3.55e-011.00e+001.20011145
GO:0005125cytokine activity3.57e-011.00e+001.19011146
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling3.60e-011.00e+001.17013148
GO:0010628positive regulation of gene expression3.62e-011.00e+001.16114149
GO:0008017microtubule binding3.64e-011.00e+001.15112150
GO:0001666response to hypoxia3.64e-011.00e+001.15111150
GO:0051260protein homooligomerization3.64e-011.00e+001.15112150
GO:0030246carbohydrate binding3.66e-011.00e+001.14111151
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription3.66e-011.00e+001.14112151
GO:0010008endosome membrane3.78e-011.00e+001.08512157
GO:0008543fibroblast growth factor receptor signaling pathway3.81e-011.00e+001.06713159
GO:0045121membrane raft3.85e-011.00e+001.04913161
GO:0008022protein C-terminus binding3.85e-011.00e+001.04914161
GO:0000398mRNA splicing, via spliceosome3.93e-011.00e+001.01312165
GO:0034220ion transmembrane transport3.96e-011.00e+000.99612167
GO:0007601visual perception3.98e-011.00e+000.98711168
GO:0038095Fc-epsilon receptor signaling pathway4.04e-011.00e+000.96213171
GO:0007420brain development4.05e-011.00e+000.95313172
GO:0007596blood coagulation4.08e-011.00e+000.52225464
GO:0016607nuclear speck4.11e-011.00e+000.92912175
GO:0031965nuclear membrane4.13e-011.00e+000.92012176
GO:0007049cell cycle4.14e-011.00e+000.91214177
GO:0043687post-translational protein modification4.21e-011.00e+000.88011181
GO:0015629actin cytoskeleton4.25e-011.00e+000.86413183
GO:0006367transcription initiation from RNA polymerase II promoter4.27e-011.00e+000.85615184
GO:0042802identical protein binding4.36e-011.00e+000.44024491
GO:0001525angiogenesis4.54e-011.00e+000.73613200
GO:0030168platelet activation4.62e-011.00e+000.70014205
GO:0001701in utero embryonic development4.70e-011.00e+000.66512210
GO:0005886plasma membrane4.85e-011.00e+000.0819242834
GO:0007399nervous system development5.24e-011.00e+000.44311245
GO:0000122negative regulation of transcription from RNA polymerase II promoter5.32e-011.00e+000.17829589
GO:0005509calcium ion binding5.32e-011.00e+000.17824589
GO:0006281DNA repair5.51e-011.00e+000.33515264
GO:0005102receptor binding5.56e-011.00e+000.31412268
GO:0042803protein homodimerization activity5.58e-011.00e+000.11124617
GO:0000166nucleotide binding5.62e-011.00e+000.29212272
GO:0048011neurotrophin TRK receptor signaling pathway5.63e-011.00e+000.28715273
GO:0003779actin binding5.66e-011.00e+000.27613275
GO:0007283spermatogenesis5.67e-011.00e+000.27112276
GO:0019899enzyme binding5.83e-011.00e+000.21015288
GO:0003677DNA binding5.87e-011.00e+00-0.0204141351
GO:0030198extracellular matrix organization5.91e-011.00e+000.17511295
GO:0005615extracellular space5.92e-011.00e+00-0.015331010
GO:0005575cellular_component6.24e-011.00e+000.04912322
GO:0008283cell proliferation6.34e-011.00e+000.00914331
GO:0043231intracellular membrane-bounded organelle6.35e-011.00e+000.00513332
GO:0007275multicellular organismal development6.48e-011.00e+00-0.04712344
GO:0006355regulation of transcription, DNA-templated6.53e-011.00e+00-0.1443101104
GO:0007268synaptic transmission6.58e-011.00e+00-0.08411353
GO:0007155cell adhesion6.89e-011.00e+00-0.20513384
GO:0009986cell surface7.23e-011.00e+00-0.34111422
GO:0045892negative regulation of transcription, DNA-templated7.25e-011.00e+00-0.34812424
GO:0006366transcription from RNA polymerase II promoter7.26e-011.00e+00-0.35213425
GO:0008150biological_process7.53e-011.00e+00-0.46313459
GO:0044281small molecule metabolic process7.57e-011.00e+00-0.3743161295
GO:0006468protein phosphorylation7.59e-011.00e+00-0.48816467
GO:0055114oxidation-reduction process7.70e-011.00e+00-0.53012481
GO:0007165signal transduction7.87e-011.00e+00-0.51227950
GO:0055085transmembrane transport7.92e-011.00e+00-0.62613514
GO:0006915apoptotic process8.26e-011.00e+00-0.77819571
GO:0046872metal ion binding8.28e-011.00e+00-0.5523141465
GO:0005789endoplasmic reticulum membrane8.58e-011.00e+00-0.93313636
GO:0005887integral component of plasma membrane9.49e-011.00e+00-1.52912961
GO:0008270zinc ion binding9.64e-011.00e+00-1.680171067
GO:0005524ATP binding9.86e-011.00e+00-2.0231191354
GO:0016021integral component of membrane1.00e+001.00e+00-2.898142483