reg-snw-91746

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.300	8.63e-08	2.46e-02	1.95e-02

chia-screen-data-Fav-reg-snw-91746 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
[ YTHDC1 ]	91746	1	-1.232	2.300	3	TF	-	-
APLP2	334	15	-2.732	2.389	4	-	Yes	Yes
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
RBM25	58517	1	-1.871	2.300	12	TF	-	-
SNAP23	8773	4	-2.073	2.430	15	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
GSTO1	9446	1	-1.437	2.300	37	TF	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
SFPQ	6421	15	-2.051	2.389	142	TF	Yes	-

Interactions (14)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GSTO1	9446	YTHDC1	91746	pd	<>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
SFPQ	6421	GSTO1	9446	pd	<>	reg.ITFP.txt: no annot
POLR2E	5434	GSTO1	9446	pd	<>	reg.ITFP.txt: no annot
RBM25	58517	YTHDC1	91746	pd	<>	reg.ITFP.txt: no annot
APLP2	334	SFPQ	6421	pd	<	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
SNAP23	8773	GSTO1	9446	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	SNAP23	8773	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot

Related GO terms (186)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0008380	RNA splicing	4.99e-05	4.87e-01	4.187	4	21	165
GO:0004832	valine-tRNA ligase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0061383	trabecula morphogenesis	1.33e-03	1.00e+00	9.553	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0014810	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	1.33e-03	1.00e+00	9.553	1	1	1
GO:0008175	tRNA methyltransferase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0005515	protein binding	2.23e-03	1.00e+00	1.003	11	198	4124
GO:0042826	histone deacetylase binding	2.59e-03	1.00e+00	4.695	2	5	58
GO:0033688	regulation of osteoblast proliferation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0050610	methylarsonate reductase activity	2.66e-03	1.00e+00	8.553	1	1	2
GO:0045174	glutathione dehydrogenase (ascorbate) activity	2.66e-03	1.00e+00	8.553	1	1	2
GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	3.99e-03	1.00e+00	7.968	1	1	3
GO:0042178	xenobiotic catabolic process	3.99e-03	1.00e+00	7.968	1	1	3
GO:0046914	transition metal ion binding	3.99e-03	1.00e+00	7.968	1	1	3
GO:0001649	osteoblast differentiation	4.19e-03	1.00e+00	4.344	2	5	74
GO:0042582	azurophil granule	5.32e-03	1.00e+00	7.553	1	1	4
GO:0036089	cleavage furrow formation	5.32e-03	1.00e+00	7.553	1	1	4
GO:0007176	regulation of epidermal growth factor-activated receptor activity	5.32e-03	1.00e+00	7.553	1	1	4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.64e-03	1.00e+00	7.231	1	2	5
GO:0043931	ossification involved in bone maturation	6.64e-03	1.00e+00	7.231	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.64e-03	1.00e+00	7.231	1	1	5
GO:0042382	paraspeckles	6.64e-03	1.00e+00	7.231	1	3	5
GO:0050847	progesterone receptor signaling pathway	7.96e-03	1.00e+00	6.968	1	2	6
GO:0002181	cytoplasmic translation	7.96e-03	1.00e+00	6.968	1	1	6
GO:0001055	RNA polymerase II activity	7.96e-03	1.00e+00	6.968	1	3	6
GO:0042754	negative regulation of circadian rhythm	7.96e-03	1.00e+00	6.968	1	2	6
GO:0043297	apical junction assembly	7.96e-03	1.00e+00	6.968	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	7.96e-03	1.00e+00	6.968	1	2	6
GO:0006903	vesicle targeting	7.96e-03	1.00e+00	6.968	1	1	6
GO:0005634	nucleus	8.61e-03	1.00e+00	1.058	9	158	3246
GO:0006397	mRNA processing	9.04e-03	1.00e+00	3.772	2	12	110
GO:0019852	L-ascorbic acid metabolic process	9.28e-03	1.00e+00	6.746	1	1	7
GO:0007617	mating behavior	9.28e-03	1.00e+00	6.746	1	1	7
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	9.28e-03	1.00e+00	6.746	1	1	7
GO:0042581	specific granule	9.28e-03	1.00e+00	6.746	1	1	7
GO:0000380	alternative mRNA splicing, via spliceosome	9.28e-03	1.00e+00	6.746	1	2	7
GO:0042981	regulation of apoptotic process	9.36e-03	1.00e+00	3.746	2	4	112
GO:0006878	cellular copper ion homeostasis	1.06e-02	1.00e+00	6.553	1	1	8
GO:0090307	spindle assembly involved in mitosis	1.06e-02	1.00e+00	6.553	1	2	8
GO:0071243	cellular response to arsenic-containing substance	1.06e-02	1.00e+00	6.553	1	1	8
GO:0006450	regulation of translational fidelity	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010388	cullin deneddylation	1.06e-02	1.00e+00	6.553	1	4	8
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	1.06e-02	1.00e+00	6.553	1	1	8
GO:0043296	apical junction complex	1.06e-02	1.00e+00	6.553	1	1	8
GO:0071354	cellular response to interleukin-6	1.19e-02	1.00e+00	6.383	1	1	9
GO:0006376	mRNA splice site selection	1.19e-02	1.00e+00	6.383	1	1	9
GO:0000398	mRNA splicing, via spliceosome	1.21e-02	1.00e+00	3.553	2	15	128
GO:0001967	suckling behavior	1.32e-02	1.00e+00	6.231	1	4	10
GO:0005736	DNA-directed RNA polymerase I complex	1.32e-02	1.00e+00	6.231	1	4	10
GO:0005095	GTPase inhibitor activity	1.32e-02	1.00e+00	6.231	1	1	10
GO:0050919	negative chemotaxis	1.32e-02	1.00e+00	6.231	1	1	10
GO:0001054	RNA polymerase I activity	1.32e-02	1.00e+00	6.231	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.46e-02	1.00e+00	6.094	1	4	11
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	1.46e-02	1.00e+00	6.094	1	1	11
GO:0044212	transcription regulatory region DNA binding	1.49e-02	1.00e+00	3.393	2	13	143
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	1.59e-02	1.00e+00	5.968	1	1	12
GO:0061025	membrane fusion	1.72e-02	1.00e+00	5.853	1	1	13
GO:0050772	positive regulation of axonogenesis	1.72e-02	1.00e+00	5.853	1	2	13
GO:0050770	regulation of axonogenesis	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0001056	RNA polymerase III activity	1.72e-02	1.00e+00	5.853	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.72e-02	1.00e+00	5.853	1	1	13
GO:0044822	poly(A) RNA binding	1.75e-02	1.00e+00	1.911	4	45	799
GO:0006386	termination of RNA polymerase III transcription	1.85e-02	1.00e+00	5.746	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.85e-02	1.00e+00	5.746	1	3	14
GO:0050771	negative regulation of axonogenesis	1.85e-02	1.00e+00	5.746	1	2	14
GO:0004364	glutathione transferase activity	1.85e-02	1.00e+00	5.746	1	1	14
GO:0043393	regulation of protein binding	1.85e-02	1.00e+00	5.746	1	2	14
GO:0016575	histone deacetylation	1.85e-02	1.00e+00	5.746	1	2	14
GO:0000188	inactivation of MAPK activity	1.98e-02	1.00e+00	5.646	1	1	15
GO:1901687	glutathione derivative biosynthetic process	1.98e-02	1.00e+00	5.646	1	1	15
GO:0070932	histone H3 deacetylation	1.98e-02	1.00e+00	5.646	1	2	15
GO:0032467	positive regulation of cytokinesis	2.11e-02	1.00e+00	5.553	1	1	16
GO:0017022	myosin binding	2.11e-02	1.00e+00	5.553	1	2	16
GO:0000166	nucleotide binding	2.21e-02	1.00e+00	3.094	2	13	176
GO:0003899	DNA-directed RNA polymerase activity	2.37e-02	1.00e+00	5.383	1	3	18
GO:0005654	nucleoplasm	2.38e-02	1.00e+00	1.778	4	68	876
GO:0036464	cytoplasmic ribonucleoprotein granule	2.50e-02	1.00e+00	5.305	1	1	19
GO:0071897	DNA biosynthetic process	2.63e-02	1.00e+00	5.231	1	2	20
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	2.76e-02	1.00e+00	5.161	1	1	21
GO:0006281	DNA repair	2.89e-02	1.00e+00	2.888	2	24	203
GO:0016604	nuclear body	3.02e-02	1.00e+00	5.029	1	2	23
GO:0010467	gene expression	3.10e-02	1.00e+00	2.075	3	49	535
GO:0006370	7-methylguanosine mRNA capping	3.15e-02	1.00e+00	4.968	1	5	24
GO:0008180	COP9 signalosome	3.15e-02	1.00e+00	4.968	1	6	24
GO:0030901	midbrain development	3.28e-02	1.00e+00	4.909	1	1	25
GO:0000976	transcription regulatory region sequence-specific DNA binding	3.28e-02	1.00e+00	4.909	1	3	25
GO:0051496	positive regulation of stress fiber assembly	3.41e-02	1.00e+00	4.853	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	3.54e-02	1.00e+00	4.798	1	4	27
GO:0005737	cytoplasm	3.61e-02	1.00e+00	0.998	7	127	2633
GO:0050885	neuromuscular process controlling balance	3.67e-02	1.00e+00	4.746	1	1	28
GO:0006418	tRNA aminoacylation for protein translation	3.79e-02	1.00e+00	4.695	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	3.79e-02	1.00e+00	4.695	1	6	29
GO:0042752	regulation of circadian rhythm	3.79e-02	1.00e+00	4.695	1	5	29
GO:0032154	cleavage furrow	3.92e-02	1.00e+00	4.646	1	3	30
GO:0003723	RNA binding	4.14e-02	1.00e+00	2.605	2	22	247
GO:0006892	post-Golgi vesicle-mediated transport	4.18e-02	1.00e+00	4.553	1	1	32
GO:0021762	substantia nigra development	4.44e-02	1.00e+00	4.466	1	1	34
GO:0007254	JNK cascade	4.44e-02	1.00e+00	4.466	1	1	34
GO:0050434	positive regulation of viral transcription	4.56e-02	1.00e+00	4.424	1	5	35
GO:0007266	Rho protein signal transduction	4.56e-02	1.00e+00	4.424	1	2	35
GO:0030900	forebrain development	4.69e-02	1.00e+00	4.383	1	2	36
GO:0030334	regulation of cell migration	4.69e-02	1.00e+00	4.383	1	2	36
GO:0048511	rhythmic process	4.95e-02	1.00e+00	4.305	1	5	38
GO:0006396	RNA processing	5.20e-02	1.00e+00	4.231	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	5.20e-02	1.00e+00	4.231	1	6	40
GO:0016491	oxidoreductase activity	5.20e-02	1.00e+00	4.231	1	1	40
GO:0070062	extracellular vesicular exosome	5.26e-02	1.00e+00	1.195	5	51	1641
GO:0005925	focal adhesion	5.26e-02	1.00e+00	2.413	2	14	282
GO:0004867	serine-type endopeptidase inhibitor activity	5.45e-02	1.00e+00	4.161	1	1	42
GO:0001047	core promoter binding	5.45e-02	1.00e+00	4.161	1	4	42
GO:0006887	exocytosis	5.71e-02	1.00e+00	4.094	1	1	44
GO:0008203	cholesterol metabolic process	6.08e-02	1.00e+00	3.998	1	2	47
GO:0007626	locomotory behavior	6.08e-02	1.00e+00	3.998	1	1	47
GO:0032481	positive regulation of type I interferon production	6.21e-02	1.00e+00	3.968	1	3	48
GO:0006310	DNA recombination	6.46e-02	1.00e+00	3.909	1	8	50
GO:0045892	negative regulation of transcription, DNA-templated	6.47e-02	1.00e+00	2.245	2	17	317
GO:0006368	transcription elongation from RNA polymerase II promoter	6.71e-02	1.00e+00	3.853	1	8	52
GO:0006289	nucleotide-excision repair	6.83e-02	1.00e+00	3.825	1	6	53
GO:0045666	positive regulation of neuron differentiation	6.83e-02	1.00e+00	3.825	1	3	53
GO:0005681	spliceosomal complex	7.08e-02	1.00e+00	3.772	1	8	55
GO:0003729	mRNA binding	7.33e-02	1.00e+00	3.720	1	4	57
GO:0000785	chromatin	7.58e-02	1.00e+00	3.670	1	6	59
GO:0071013	catalytic step 2 spliceosome	7.83e-02	1.00e+00	3.622	1	5	61
GO:0030308	negative regulation of cell growth	8.93e-02	1.00e+00	3.424	1	3	70
GO:0010951	negative regulation of endopeptidase activity	9.06e-02	1.00e+00	3.403	1	2	71
GO:0030496	midbody	9.30e-02	1.00e+00	3.363	1	6	73
GO:0016363	nuclear matrix	9.30e-02	1.00e+00	3.363	1	10	73
GO:0051056	regulation of small GTPase mediated signal transduction	9.66e-02	1.00e+00	3.305	1	2	76
GO:0005938	cell cortex	9.79e-02	1.00e+00	3.286	1	6	77
GO:0030529	ribonucleoprotein complex	1.04e-01	1.00e+00	3.195	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	1.05e-01	1.00e+00	3.178	1	2	83
GO:0045202	synapse	1.05e-01	1.00e+00	3.178	1	3	83
GO:0016032	viral process	1.09e-01	1.00e+00	1.811	2	30	428
GO:0030027	lamellipodium	1.11e-01	1.00e+00	3.094	1	3	88
GO:0061024	membrane organization	1.12e-01	1.00e+00	3.077	1	2	89
GO:0030036	actin cytoskeleton organization	1.13e-01	1.00e+00	3.061	1	4	90
GO:0008201	heparin binding	1.15e-01	1.00e+00	3.045	1	4	91
GO:0006805	xenobiotic metabolic process	1.18e-01	1.00e+00	2.998	1	3	94
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.21e-01	1.00e+00	1.720	2	29	456
GO:0003677	DNA binding	1.25e-01	1.00e+00	1.251	3	52	947
GO:0007179	transforming growth factor beta receptor signaling pathway	1.34e-01	1.00e+00	2.811	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.35e-01	1.00e+00	2.798	1	2	108
GO:0043005	neuron projection	1.41e-01	1.00e+00	2.733	1	6	113
GO:0007049	cell cycle	1.43e-01	1.00e+00	2.707	1	8	115
GO:0003924	GTPase activity	1.47e-01	1.00e+00	2.658	1	7	119
GO:0016607	nuclear speck	1.51e-01	1.00e+00	2.622	1	8	122
GO:0006184	GTP catabolic process	1.60e-01	1.00e+00	2.531	1	7	130
GO:0030168	platelet activation	1.72e-01	1.00e+00	2.413	1	5	141
GO:0006367	transcription initiation from RNA polymerase II promoter	1.94e-01	1.00e+00	2.222	1	18	161
GO:0005829	cytosol	2.02e-01	1.00e+00	0.750	4	88	1787
GO:0007264	small GTPase mediated signal transduction	2.09e-01	1.00e+00	2.110	1	8	174
GO:0016020	membrane	2.11e-01	1.00e+00	0.901	3	56	1207
GO:0005739	mitochondrion	2.17e-01	1.00e+00	1.189	2	32	659
GO:0005856	cytoskeleton	2.26e-01	1.00e+00	1.983	1	8	190
GO:0005743	mitochondrial inner membrane	2.33e-01	1.00e+00	1.931	1	9	197
GO:0005525	GTP binding	2.33e-01	1.00e+00	1.931	1	12	197
GO:0048011	neurotrophin TRK receptor signaling pathway	2.35e-01	1.00e+00	1.916	1	8	199
GO:0015031	protein transport	2.39e-01	1.00e+00	1.888	1	10	203
GO:0019899	enzyme binding	2.46e-01	1.00e+00	1.839	1	7	210
GO:0030054	cell junction	2.54e-01	1.00e+00	1.785	1	5	218
GO:0030198	extracellular matrix organization	2.58e-01	1.00e+00	1.765	1	7	221
GO:0007186	G-protein coupled receptor signaling pathway	2.66e-01	1.00e+00	1.714	1	4	229
GO:0007411	axon guidance	2.74e-01	1.00e+00	1.664	1	8	237
GO:0008285	negative regulation of cell proliferation	3.12e-01	1.00e+00	1.439	1	11	277
GO:0009986	cell surface	3.25e-01	1.00e+00	1.368	1	5	291
GO:0005524	ATP binding	3.36e-01	1.00e+00	0.752	2	37	892
GO:0055114	oxidation-reduction process	3.41e-01	1.00e+00	1.286	1	9	308
GO:0007596	blood coagulation	3.68e-01	1.00e+00	1.148	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	3.70e-01	1.00e+00	1.139	1	23	341
GO:0042802	identical protein binding	3.81e-01	1.00e+00	1.085	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	4.01e-01	1.00e+00	0.995	1	21	377
GO:0005886	plasma membrane	4.33e-01	1.00e+00	0.337	3	46	1784
GO:0045087	innate immune response	4.60e-01	1.00e+00	0.733	1	12	452
GO:0005730	nucleolus	4.95e-01	1.00e+00	0.304	2	74	1217
GO:0005887	integral component of plasma membrane	5.46e-01	1.00e+00	0.386	1	8	575
GO:0007165	signal transduction	5.73e-01	1.00e+00	0.282	1	24	618
GO:0006355	regulation of transcription, DNA-templated	6.28e-01	1.00e+00	0.071	1	31	715
GO:0044281	small molecule metabolic process	6.91e-01	1.00e+00	-0.168	1	35	844
GO:0006351	transcription, DNA-templated	7.81e-01	1.00e+00	-0.518	1	47	1076
GO:0016021	integral component of membrane	8.90e-01	1.00e+00	-1.023	1	19	1526

chia-Fav

reg-snw-91746

Statistics

Genes (13)

Interactions (14)

Related GO terms (186)