reg-snw-9063

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.308 7.88e-08 2.34e-02 1.86e-02
chia-screen-data-Fav-reg-snw-9063 subnetwork

Genes (16)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
DTX3L 151636 2-1.9072.30813TF--
NDUFA4L2 56901 44-2.4772.45921-Yes-
FOXJ3 22887 15-2.4072.36987TFYesYes
EIF2S2 8894 40-2.9992.45922-YesYes
NCBP1 4686 41-2.5102.45944-YesYes
PHB 5245 82-2.7432.68936-YesYes
REXO1 57455 12-2.3032.369130TFYes-
[ PIAS2 ] 9063 2-1.1362.30822TF--
KIAA1551 55196 6-1.8522.36935---
ENPP7 339221 10-2.5692.3696-YesYes
APC 324 5-2.2932.30831TFYes-
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
KLHL8 57563 4-1.9932.30830TF--
FBXO22 26263 36-1.7392.459208TF--
NCOA2 10499 4-1.7862.32695TF--

Interactions (18)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FBXO22 26263 KIAA1551 55196 pd > reg.ITFP.txt: no annot
FOXJ3 22887 REXO1 57455 pd <> reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
APC 324 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
FOXJ3 22887 KIAA1551 55196 pd > reg.ITFP.txt: no annot
APC 324 NCOA2 10499 pd <> reg.ITFP.txt: no annot
KIAA1551 55196 KLHL8 57563 pd < reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
KIAA1551 55196 DTX3L 151636 pd < reg.ITFP.txt: no annot
PIAS2 9063 KIAA1551 55196 pd > reg.ITFP.txt: no annot
REXO1 57455 ENPP7 339221 pd > reg.ITFP.txt: no annot
KIAA1551 55196 REXO1 57455 pd < reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
APC 324 KIAA1551 55196 pd > reg.ITFP.txt: no annot
NCOA2 10499 KIAA1551 55196 pd > reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot

Related GO terms (205)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0045667regulation of osteoblast differentiation7.01e-056.84e-017.253228
GO:0060766negative regulation of androgen receptor signaling pathway1.37e-041.00e+006.7942411
GO:0051171regulation of nitrogen compound metabolic process1.64e-031.00e+009.253111
GO:0042483negative regulation of odontogenesis1.64e-031.00e+009.253111
GO:0048742regulation of skeletal muscle fiber development3.27e-031.00e+008.253112
GO:0006684sphingomyelin metabolic process3.27e-031.00e+008.253112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process3.27e-031.00e+008.253112
GO:0005846nuclear cap binding complex3.27e-031.00e+008.253112
GO:0002176male germ cell proliferation3.27e-031.00e+008.253112
GO:0009798axis specification3.27e-031.00e+008.253112
GO:0005850eukaryotic translation initiation factor 2 complex4.91e-031.00e+007.668123
GO:0030375thyroid hormone receptor coactivator activity4.91e-031.00e+007.668113
GO:0004767sphingomyelin phosphodiesterase activity4.91e-031.00e+007.668113
GO:0019887protein kinase regulator activity4.91e-031.00e+007.668123
GO:0045292mRNA cis splicing, via spliceosome6.54e-031.00e+007.253114
GO:0031442positive regulation of mRNA 3'-end processing6.54e-031.00e+007.253114
GO:0006290pyrimidine dimer repair6.54e-031.00e+007.253124
GO:0007091metaphase/anaphase transition of mitotic cell cycle8.17e-031.00e+006.931125
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development8.17e-031.00e+006.931115
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic process8.17e-031.00e+006.931115
GO:0031274positive regulation of pseudopodium assembly8.17e-031.00e+006.931115
GO:0006282regulation of DNA repair8.17e-031.00e+006.931125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway8.17e-031.00e+006.931115
GO:0008285negative regulation of cell proliferation9.61e-031.00e+002.725311277
GO:0030858positive regulation of epithelial cell differentiation9.79e-031.00e+006.668116
GO:0050847progesterone receptor signaling pathway9.79e-031.00e+006.668126
GO:0045670regulation of osteoclast differentiation1.14e-021.00e+006.446117
GO:0000731DNA synthesis involved in DNA repair1.14e-021.00e+006.446117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.14e-021.00e+006.446117
GO:0006301postreplication repair1.14e-021.00e+006.446127
GO:0000339RNA cap binding1.14e-021.00e+006.446117
GO:0030877beta-catenin destruction complex1.14e-021.00e+006.446117
GO:2000273positive regulation of receptor activity1.30e-021.00e+006.253118
GO:0031116positive regulation of microtubule polymerization1.30e-021.00e+006.253118
GO:0005845mRNA cap binding complex1.30e-021.00e+006.253118
GO:0031122cytoplasmic microtubule organization1.30e-021.00e+006.253118
GO:0010944negative regulation of transcription by competitive promoter binding1.30e-021.00e+006.253118
GO:0010388cullin deneddylation1.30e-021.00e+006.253148
GO:0010390histone monoubiquitination1.30e-021.00e+006.253128
GO:0045295gamma-catenin binding1.47e-021.00e+006.083119
GO:0010225response to UV-C1.47e-021.00e+006.083129
GO:0019789SUMO ligase activity1.47e-021.00e+006.083119
GO:0032886regulation of microtubule-based process1.47e-021.00e+006.083119
GO:0044295axonal growth cone1.47e-021.00e+006.083119
GO:0006379mRNA cleavage1.47e-021.00e+006.083129
GO:0071354cellular response to interleukin-61.47e-021.00e+006.083119
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.47e-021.00e+006.083129
GO:0005634nucleus1.55e-021.00e+000.911101583246
GO:0005095GTPase inhibitor activity1.63e-021.00e+005.9311110
GO:0006974cellular response to DNA damage stimulus1.63e-021.00e+003.335211121
GO:0043409negative regulation of MAPK cascade1.63e-021.00e+005.9311110
GO:0051010microtubule plus-end binding1.79e-021.00e+005.7941211
GO:0007026negative regulation of microtubule depolymerization1.79e-021.00e+005.7941211
GO:0046716muscle cell cellular homeostasis1.79e-021.00e+005.7941111
GO:0008334histone mRNA metabolic process1.79e-021.00e+005.7941111
GO:0051276chromosome organization1.95e-021.00e+005.6681212
GO:0004527exonuclease activity1.95e-021.00e+005.6681412
GO:0035371microtubule plus-end2.11e-021.00e+005.5531213
GO:0010906regulation of glucose metabolic process2.11e-021.00e+005.5531113
GO:0008156negative regulation of DNA replication2.11e-021.00e+005.5531113
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity2.27e-021.00e+005.4461314
GO:0016575histone deacetylation2.27e-021.00e+005.4461214
GO:0008135translation factor activity, nucleic acid binding2.43e-021.00e+005.3471415
GO:0016922ligand-dependent nuclear receptor binding2.43e-021.00e+005.3471215
GO:0000188inactivation of MAPK activity2.43e-021.00e+005.3471115
GO:0000281mitotic cytokinesis2.43e-021.00e+005.3471315
GO:0031463Cul3-RING ubiquitin ligase complex2.59e-021.00e+005.2531116
GO:0003887DNA-directed DNA polymerase activity2.59e-021.00e+005.2531216
GO:0009954proximal/distal pattern formation2.75e-021.00e+005.1661217
GO:0009953dorsal/ventral pattern formation2.91e-021.00e+005.0831218
GO:0031047gene silencing by RNA2.91e-021.00e+005.0831218
GO:0035257nuclear hormone receptor binding2.91e-021.00e+005.0831118
GO:0016573histone acetylation3.07e-021.00e+005.0051119
GO:0006913nucleocytoplasmic transport3.23e-021.00e+004.9311220
GO:0045296cadherin binding3.23e-021.00e+004.9311220
GO:0071897DNA biosynthetic process3.23e-021.00e+004.9311220
GO:0034660ncRNA metabolic process3.23e-021.00e+004.9311120
GO:0001942hair follicle development3.39e-021.00e+004.8611221
GO:0004842ubiquitin-protein transferase activity3.39e-021.00e+002.770217179
GO:0016925protein sumoylation3.55e-021.00e+004.7941322
GO:0051781positive regulation of cell division3.55e-021.00e+004.7941222
GO:0000387spliceosomal snRNP assembly3.55e-021.00e+004.7941122
GO:0006687glycosphingolipid metabolic process3.55e-021.00e+004.7941122
GO:0003713transcription coactivator activity3.56e-021.00e+002.730221184
GO:0005881cytoplasmic microtubule3.86e-021.00e+004.6681324
GO:00063707-methylguanosine mRNA capping3.86e-021.00e+004.6681524
GO:0008180COP9 signalosome3.86e-021.00e+004.6681624
GO:0005902microvillus4.02e-021.00e+004.6101125
GO:0048538thymus development4.02e-021.00e+004.6101125
GO:0005913cell-cell adherens junction4.02e-021.00e+004.6101325
GO:0007094mitotic spindle assembly checkpoint4.02e-021.00e+004.6101425
GO:0009267cellular response to starvation4.18e-021.00e+004.5531126
GO:0033077T cell differentiation in thymus4.18e-021.00e+004.5531226
GO:0045785positive regulation of cell adhesion4.65e-021.00e+004.3951329
GO:0070830tight junction assembly4.65e-021.00e+004.3951129
GO:0006446regulation of translational initiation4.65e-021.00e+004.3951229
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity4.81e-021.00e+004.3471330
GO:0004402histone acetyltransferase activity4.81e-021.00e+004.3471330
GO:0050681androgen receptor binding4.81e-021.00e+004.3471230
GO:0005654nucleoplasm4.89e-021.00e+001.479468876
GO:0090305nucleic acid phosphodiester bond hydrolysis4.96e-021.00e+004.2991631
GO:0016328lateral plasma membrane4.96e-021.00e+004.2991231
GO:0006921cellular component disassembly involved in execution phase of apoptosis4.96e-021.00e+004.2991131
GO:0035019somatic stem cell maintenance5.12e-021.00e+004.2531332
GO:0007254JNK cascade5.43e-021.00e+004.1661134
GO:0060041retina development in camera-type eye5.43e-021.00e+004.1661134
GO:0045732positive regulation of protein catabolic process5.43e-021.00e+004.1661134
GO:0050434positive regulation of viral transcription5.59e-021.00e+004.1241535
GO:0030521androgen receptor signaling pathway5.59e-021.00e+004.1241335
GO:0031124mRNA 3'-end processing5.59e-021.00e+004.1241435
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process5.90e-021.00e+004.0441237
GO:0003743translation initiation factor activity5.90e-021.00e+004.0441837
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process6.05e-021.00e+004.0051438
GO:0006665sphingolipid metabolic process6.05e-021.00e+004.0051138
GO:0006369termination of RNA polymerase II transcription6.05e-021.00e+004.0051538
GO:0003723RNA binding6.06e-021.00e+002.305222247
GO:0003684damaged DNA binding6.52e-021.00e+003.8961141
GO:0006406mRNA export from nucleus6.98e-021.00e+003.7941744
GO:0007409axonogenesis7.13e-021.00e+003.7621245
GO:0008013beta-catenin binding7.13e-021.00e+003.7621345
GO:0032587ruffle membrane7.89e-021.00e+003.6101350
GO:0060070canonical Wnt signaling pathway8.04e-021.00e+003.5811151
GO:0001822kidney development8.19e-021.00e+003.5531352
GO:0006368transcription elongation from RNA polymerase II promoter8.19e-021.00e+003.5531852
GO:0006302double-strand break repair8.19e-021.00e+003.5531552
GO:0042393histone binding8.50e-021.00e+003.4991354
GO:0000776kinetochore8.65e-021.00e+003.4721855
GO:0008584male gonad development8.95e-021.00e+003.4211157
GO:0042826histone deacetylase binding9.10e-021.00e+003.3951558
GO:0090090negative regulation of canonical Wnt signaling pathway9.25e-021.00e+003.3711559
GO:0009952anterior/posterior pattern specification9.40e-021.00e+003.3471360
GO:0006464cellular protein modification process9.55e-021.00e+003.3231461
GO:0030018Z disc9.99e-021.00e+003.2531364
GO:0005923tight junction9.99e-021.00e+003.2531264
GO:0003676nucleic acid binding1.03e-011.00e+003.2091466
GO:0006355regulation of transcription, DNA-templated1.07e-011.00e+001.357331715
GO:0030308negative regulation of cell growth1.09e-011.00e+003.1241370
GO:0001649osteoblast differentiation1.15e-011.00e+003.0441574
GO:0016605PML body1.22e-011.00e+002.9501579
GO:0045893positive regulation of transcription, DNA-templated1.25e-011.00e+001.695221377
GO:0030529ribonucleoprotein complex1.26e-011.00e+002.8961582
GO:0005730nucleolus1.29e-011.00e+001.0044741217
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.29e-011.00e+002.8611584
GO:0030027lamellipodium1.35e-011.00e+002.7941388
GO:0044255cellular lipid metabolic process1.36e-011.00e+002.7781289
GO:0006461protein complex assembly1.39e-011.00e+002.7461291
GO:0000209protein polyubiquitination1.41e-011.00e+002.7301692
GO:0006511ubiquitin-dependent protein catabolic process1.41e-011.00e+002.7301692
GO:0007050cell cycle arrest1.41e-011.00e+002.7301492
GO:0006260DNA replication1.43e-011.00e+002.6991994
GO:0046983protein dimerization activity1.43e-011.00e+002.6991294
GO:0016477cell migration1.46e-011.00e+002.6681396
GO:0008017microtubule binding1.48e-011.00e+002.6531997
GO:0006413translational initiation1.51e-011.00e+002.6241699
GO:0030335positive regulation of cell migration1.53e-011.00e+002.59512101
GO:0042981regulation of apoptotic process1.69e-011.00e+002.44614112
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.70e-011.00e+001.421229456
GO:0007049cell cycle1.73e-011.00e+002.40818115
GO:0016607nuclear speck1.82e-011.00e+002.32318122
GO:0005515protein binding1.88e-011.00e+000.41491984124
GO:0000398mRNA splicing, via spliceosome1.90e-011.00e+002.253115128
GO:0031625ubiquitin protein ligase binding2.04e-011.00e+002.14517138
GO:0044212transcription regulatory region DNA binding2.10e-011.00e+002.094113143
GO:0016874ligase activity2.14e-011.00e+002.064111146
GO:0004871signal transducer activity2.17e-011.00e+002.04414148
GO:0010467gene expression2.18e-011.00e+001.190249535
GO:0001701in utero embryonic development2.25e-011.00e+001.98717154
GO:0008380RNA splicing2.39e-011.00e+001.887121165
GO:0005737cytoplasm2.45e-011.00e+000.47661272633
GO:0016071mRNA metabolic process2.45e-011.00e+001.844110170
GO:0006412translation2.55e-011.00e+001.778112178
GO:0006351transcription, DNA-templated2.55e-011.00e+000.7673471076
GO:0016567protein ubiquitination2.67e-011.00e+001.699114188
GO:0016070RNA metabolic process2.67e-011.00e+001.699110188
GO:0007165signal transduction2.69e-011.00e+000.982224618
GO:0005743mitochondrial inner membrane2.78e-011.00e+001.63119197
GO:0043065positive regulation of apoptotic process2.84e-011.00e+001.59517202
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.85e-011.00e+000.922229644
GO:0006281DNA repair2.86e-011.00e+001.588124203
GO:0008134transcription factor binding2.93e-011.00e+001.546110209
GO:0005739mitochondrion2.94e-011.00e+000.889232659
GO:0019899enzyme binding2.94e-011.00e+001.53917210
GO:0005813centrosome3.02e-011.00e+001.492110217
GO:0019901protein kinase binding3.20e-011.00e+001.39518232
GO:0007155cell adhesion3.33e-011.00e+001.32318244
GO:0008270zinc ion binding3.37e-011.00e+000.748239727
GO:0003682chromatin binding3.42e-011.00e+001.276115252
GO:0043565sequence-specific DNA binding3.67e-011.00e+001.15018275
GO:0044822poly(A) RNA binding3.81e-011.00e+000.611245799
GO:0044281small molecule metabolic process4.08e-011.00e+000.532235844
GO:0045892negative regulation of transcription, DNA-templated4.10e-011.00e+000.945117317
GO:0006366transcription from RNA polymerase II promoter4.34e-011.00e+000.840123341
GO:0044267cellular protein metabolic process4.44e-011.00e+000.794114352
GO:0046872metal ion binding4.61e-011.00e+000.386224934
GO:0006915apoptotic process4.98e-011.00e+000.570115411
GO:0005794Golgi apparatus5.01e-011.00e+000.55616415
GO:0016032viral process5.12e-011.00e+000.512130428
GO:0005886plasma membrane5.81e-011.00e+000.0373461784
GO:0005829cytosol5.82e-011.00e+000.0353881787
GO:0016020membrane6.06e-011.00e+000.0162561207
GO:0005887integral component of plasma membrane6.22e-011.00e+000.08618575
GO:0003700sequence-specific DNA binding transcription factor activity6.26e-011.00e+000.069122582
GO:0003677DNA binding8.05e-011.00e+00-0.634152947
GO:0016021integral component of membrane9.34e-011.00e+00-1.3221191526
GO:0070062extracellular vesicular exosome9.47e-011.00e+00-1.4271511641