reg-snw-90480

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.431 1.64e-08 9.48e-03 8.30e-03
chia-screen-data-Fav-reg-snw-90480 subnetwork

Genes (8)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
[ GADD45GIP1 ] 90480 1-1.0922.4316---
VARS 7407 60-2.3662.689124TFYes-
FBXL6 26233 28-2.2532.68922-Yes-
HNRNPU 3192 39-2.8692.64433-Yes-
GPS1 2873 86-3.6212.68936TFYesYes
PHB 5245 82-2.7432.68936-YesYes
POLR2E 5434 30-2.0372.644201TFYes-
FTSJ1 24140 43-2.4632.68935-YesYes

Interactions (8)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PHB 5245 VARS 7407 pd < reg.ITFP.txt: no annot
VARS 7407 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLR2E 5434 FTSJ1 24140 pd > reg.ITFP.txt: no annot
POLR2E 5434 VARS 7407 pd <> reg.ITFP.txt: no annot
VARS 7407 GADD45GIP1 90480 pd > reg.ITFP.txt: no annot
HNRNPU 3192 POLR2E 5434 pd < reg.ITFP.txt: no annot
VARS 7407 FBXL6 26233 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot

Related GO terms (82)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0004832valine-tRNA ligase activity8.19e-041.00e+0010.253111
GO:0002128tRNA nucleoside ribose methylation8.19e-041.00e+0010.253111
GO:0006438valyl-tRNA aminoacylation8.19e-041.00e+0010.253111
GO:0008175tRNA methyltransferase activity8.19e-041.00e+0010.253111
GO:0001649osteoblast differentiation1.54e-031.00e+005.0442574
GO:0007049cell cycle3.68e-031.00e+004.40828115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway4.09e-031.00e+007.931115
GO:0002161aminoacyl-tRNA editing activity4.09e-031.00e+007.931115
GO:0070934CRD-mediated mRNA stabilization4.09e-031.00e+007.931125
GO:0000398mRNA splicing, via spliceosome4.53e-031.00e+004.253215128
GO:0050847progesterone receptor signaling pathway4.91e-031.00e+007.668126
GO:0002181cytoplasmic translation4.91e-031.00e+007.668116
GO:0070937CRD-mediated mRNA stability complex4.91e-031.00e+007.668126
GO:0001055RNA polymerase II activity4.91e-031.00e+007.668136
GO:0010944negative regulation of transcription by competitive promoter binding6.54e-031.00e+007.253118
GO:0010388cullin deneddylation6.54e-031.00e+007.253148
GO:0006450regulation of translational fidelity6.54e-031.00e+007.253118
GO:0071354cellular response to interleukin-67.35e-031.00e+007.083119
GO:0008380RNA splicing7.43e-031.00e+003.887221165
GO:0010467gene expression7.44e-031.00e+002.775349535
GO:0005736DNA-directed RNA polymerase I complex8.17e-031.00e+006.9311410
GO:0001054RNA polymerase I activity8.17e-031.00e+006.9311410
GO:0005095GTPase inhibitor activity8.17e-031.00e+006.9311110
GO:0060766negative regulation of androgen receptor signaling pathway8.98e-031.00e+006.7941411
GO:0005665DNA-directed RNA polymerase II, core complex1.06e-021.00e+006.5531313
GO:0001056RNA polymerase III activity1.06e-021.00e+006.5531313
GO:0005666DNA-directed RNA polymerase III complex1.06e-021.00e+006.5531313
GO:0006385transcription elongation from RNA polymerase III promoter1.14e-021.00e+006.4461314
GO:0006386termination of RNA polymerase III transcription1.14e-021.00e+006.4461314
GO:0016575histone deacetylation1.14e-021.00e+006.4461214
GO:0000188inactivation of MAPK activity1.22e-021.00e+006.3471115
GO:0005739mitochondrion1.33e-021.00e+002.474332659
GO:0003899DNA-directed RNA polymerase activity1.47e-021.00e+006.0831318
GO:0036464cytoplasmic ribonucleoprotein granule1.55e-021.00e+006.0051119
GO:0071897DNA biosynthetic process1.63e-021.00e+005.9311220
GO:0008180COP9 signalosome1.95e-021.00e+005.6681624
GO:00063707-methylguanosine mRNA capping1.95e-021.00e+005.6681524
GO:0006360transcription from RNA polymerase I promoter2.19e-021.00e+005.4991427
GO:0006418tRNA aminoacylation for protein translation2.35e-021.00e+005.3951429
GO:0006383transcription from RNA polymerase III promoter2.35e-021.00e+005.3951629
GO:0007254JNK cascade2.75e-021.00e+005.1661134
GO:0050434positive regulation of viral transcription2.83e-021.00e+005.1241535
GO:0005654nucleoplasm2.86e-021.00e+002.064368876
GO:0006396RNA processing3.23e-021.00e+004.9311440
GO:0006283transcription-coupled nucleotide-excision repair3.23e-021.00e+004.9311640
GO:0032481positive regulation of type I interferon production3.87e-021.00e+004.6681348
GO:0006368transcription elongation from RNA polymerase II promoter4.18e-021.00e+004.5531852
GO:0006289nucleotide-excision repair4.26e-021.00e+004.5251653
GO:0016032viral process4.50e-021.00e+002.512230428
GO:0042826histone deacetylase binding4.66e-021.00e+004.3951558
GO:0071013catalytic step 2 spliceosome4.89e-021.00e+004.3231561
GO:0030308negative regulation of cell growth5.59e-021.00e+004.1241370
GO:0030529ribonucleoprotein complex6.53e-021.00e+003.8961582
GO:0005634nucleus8.69e-021.00e+000.91151583246
GO:0042981regulation of apoptotic process8.82e-021.00e+003.44614112
GO:0044212transcription regulatory region DNA binding1.11e-011.00e+003.094113143
GO:0006367transcription initiation from RNA polymerase II promoter1.25e-011.00e+002.922118161
GO:0004842ubiquitin-protein transferase activity1.38e-011.00e+002.770117179
GO:0016567protein ubiquitination1.44e-011.00e+002.699114188
GO:0005743mitochondrial inner membrane1.50e-011.00e+002.63119197
GO:0006281DNA repair1.55e-011.00e+002.588124203
GO:0019899enzyme binding1.60e-011.00e+002.53917210
GO:0005524ATP binding1.61e-011.00e+001.453237892
GO:0003677DNA binding1.78e-011.00e+001.366252947
GO:0003723RNA binding1.85e-011.00e+002.305122247
GO:0006508proteolysis1.97e-011.00e+002.209111264
GO:0008285negative regulation of cell proliferation2.06e-011.00e+002.140111277
GO:0005515protein binding2.10e-011.00e+000.56651984124
GO:0009986cell surface2.15e-011.00e+002.06915291
GO:0045892negative regulation of transcription, DNA-templated2.32e-011.00e+001.945117317
GO:0006366transcription from RNA polymerase II promoter2.48e-011.00e+001.840123341
GO:0016020membrane2.59e-011.00e+001.0162561207
GO:0045893positive regulation of transcription, DNA-templated2.70e-011.00e+001.695121377
GO:0045087innate immune response3.16e-011.00e+001.433112452
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.18e-011.00e+001.421129456
GO:0005737cytoplasm3.71e-011.00e+000.47631272633
GO:0005887integral component of plasma membrane3.85e-011.00e+001.08618575
GO:0007165signal transduction4.07e-011.00e+000.982124618
GO:0005829cytosol4.46e-011.00e+000.4502881787
GO:0006355regulation of transcription, DNA-templated4.56e-011.00e+000.772131715
GO:0044822poly(A) RNA binding4.95e-011.00e+000.611145799
GO:0070062extracellular vesicular exosome7.71e-011.00e+00-0.4271511641