reg-snw-8458

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.382	3.10e-08	1.38e-02	1.16e-02

chia-screen-data-Fav-reg-snw-8458 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
TPR	7175	10	-2.638	2.445	36	TF	Yes	Yes
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
MED28	80306	8	-2.404	2.445	6	-	Yes	-
CBLL1	79872	9	-1.897	2.445	38	TF	-	-
[ TTF2 ]	8458	6	-1.646	2.382	76	TF	-	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CBLL1	79872	MED28	80306	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
NCBP1	4686	TPR	7175	pd	<	reg.ITFP.txt: no annot
NCBP1	4686	CBLL1	79872	pd	<	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
TTF2	8458	CBLL1	79872	pd	<>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
TTF2	8458	AGPS	8540	pd	>	reg.ITFP.txt: no annot

Related GO terms (159)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006369	termination of RNA polymerase II transcription	4.49e-06	4.39e-02	6.421	3	5	38
GO:0008380	RNA splicing	9.27e-06	9.05e-02	4.717	4	21	165
GO:0006379	mRNA cleavage	2.71e-05	2.65e-01	7.914	2	2	9
GO:0003723	RNA binding	4.56e-05	4.45e-01	4.135	4	22	247
GO:0030529	ribonucleoprotein complex	4.62e-05	4.51e-01	5.311	3	5	82
GO:0000398	mRNA splicing, via spliceosome	1.74e-04	1.00e+00	4.668	3	15	128
GO:0031124	mRNA 3'-end processing	4.42e-04	1.00e+00	5.954	2	4	35
GO:0006406	mRNA export from nucleus	7.00e-04	1.00e+00	5.624	2	7	44
GO:0016149	translation release factor activity, codon specific	9.22e-04	1.00e+00	10.083	1	1	1
GO:1901673	regulation of spindle assembly involved in mitosis	9.22e-04	1.00e+00	10.083	1	1	1
GO:0043578	nuclear matrix organization	9.22e-04	1.00e+00	10.083	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0008079	translation termination factor activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006404	RNA import into nucleus	9.22e-04	1.00e+00	10.083	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	9.22e-04	1.00e+00	10.083	1	1	1
GO:0000189	MAPK import into nucleus	1.84e-03	1.00e+00	9.083	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	1.84e-03	1.00e+00	9.083	1	1	2
GO:0003747	translation release factor activity	1.84e-03	1.00e+00	9.083	1	2	2
GO:0006353	DNA-templated transcription, termination	1.84e-03	1.00e+00	9.083	1	1	2
GO:0042306	regulation of protein import into nucleus	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005846	nuclear cap binding complex	1.84e-03	1.00e+00	9.083	1	1	2
GO:0070840	dynein complex binding	1.84e-03	1.00e+00	9.083	1	1	2
GO:0008611	ether lipid biosynthetic process	1.84e-03	1.00e+00	9.083	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	1.84e-03	1.00e+00	9.083	1	1	2
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.53e-03	1.00e+00	4.691	2	5	84
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006405	RNA export from nucleus	2.76e-03	1.00e+00	8.499	1	1	3
GO:0010793	regulation of mRNA export from nucleus	2.76e-03	1.00e+00	8.499	1	1	3
GO:0051151	negative regulation of smooth muscle cell differentiation	3.68e-03	1.00e+00	8.083	1	1	4
GO:0045292	mRNA cis splicing, via spliceosome	3.68e-03	1.00e+00	8.083	1	1	4
GO:0097452	GAIT complex	3.68e-03	1.00e+00	8.083	1	2	4
GO:0031442	positive regulation of mRNA 3'-end processing	3.68e-03	1.00e+00	8.083	1	1	4
GO:0006449	regulation of translational termination	3.68e-03	1.00e+00	8.083	1	1	4
GO:0006999	nuclear pore organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0070849	response to epidermal growth factor	3.68e-03	1.00e+00	8.083	1	1	4
GO:0044615	nuclear pore nuclear basket	3.68e-03	1.00e+00	8.083	1	1	4
GO:0044822	poly(A) RNA binding	4.01e-03	1.00e+00	2.441	4	45	799
GO:0004521	endoribonuclease activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0008610	lipid biosynthetic process	4.60e-03	1.00e+00	7.762	1	1	5
GO:0006398	histone mRNA 3'-end processing	4.60e-03	1.00e+00	7.762	1	1	5
GO:0046825	regulation of protein export from nucleus	4.60e-03	1.00e+00	7.762	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.60e-03	1.00e+00	7.762	1	2	5
GO:0043495	protein anchor	4.60e-03	1.00e+00	7.762	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.52e-03	1.00e+00	7.499	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	5.52e-03	1.00e+00	7.499	1	2	6
GO:0005654	nucleoplasm	5.61e-03	1.00e+00	2.309	4	68	876
GO:0005515	protein binding	5.67e-03	1.00e+00	1.074	8	198	4124
GO:0016032	viral process	5.76e-03	1.00e+00	2.927	3	30	428
GO:0008409	5'-3' exonuclease activity	6.44e-03	1.00e+00	7.276	1	2	7
GO:0000339	RNA cap binding	6.44e-03	1.00e+00	7.276	1	1	7
GO:0005868	cytoplasmic dynein complex	6.44e-03	1.00e+00	7.276	1	1	7
GO:0005845	mRNA cap binding complex	7.35e-03	1.00e+00	7.083	1	1	8
GO:0042405	nuclear inclusion body	7.35e-03	1.00e+00	7.083	1	1	8
GO:0051292	nuclear pore complex assembly	7.35e-03	1.00e+00	7.083	1	4	8
GO:0071949	FAD binding	7.35e-03	1.00e+00	7.083	1	1	8
GO:0035457	cellular response to interferon-alpha	7.35e-03	1.00e+00	7.083	1	1	8
GO:0045947	negative regulation of translational initiation	8.27e-03	1.00e+00	6.914	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	8.27e-03	1.00e+00	6.914	1	3	9
GO:0008143	poly(A) binding	9.18e-03	1.00e+00	6.762	1	2	10
GO:0016071	mRNA metabolic process	1.00e-02	1.00e+00	3.674	2	10	170
GO:0006479	protein methylation	1.01e-02	1.00e+00	6.624	1	2	11
GO:0051019	mitogen-activated protein kinase binding	1.01e-02	1.00e+00	6.624	1	1	11
GO:0008023	transcription elongation factor complex	1.01e-02	1.00e+00	6.624	1	2	11
GO:0008334	histone mRNA metabolic process	1.01e-02	1.00e+00	6.624	1	1	11
GO:0090316	positive regulation of intracellular protein transport	1.01e-02	1.00e+00	6.624	1	1	11
GO:0045807	positive regulation of endocytosis	1.01e-02	1.00e+00	6.624	1	1	11
GO:0005487	nucleocytoplasmic transporter activity	1.01e-02	1.00e+00	6.624	1	2	11
GO:0046827	positive regulation of protein export from nucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0010467	gene expression	1.07e-02	1.00e+00	2.605	3	49	535
GO:0042307	positive regulation of protein import into nucleus	1.10e-02	1.00e+00	6.499	1	3	12
GO:0034399	nuclear periphery	1.10e-02	1.00e+00	6.499	1	3	12
GO:0016070	RNA metabolic process	1.21e-02	1.00e+00	3.529	2	10	188
GO:0030864	cortical actin cytoskeleton	1.47e-02	1.00e+00	6.083	1	1	16
GO:0005782	peroxisomal matrix	1.47e-02	1.00e+00	6.083	1	1	16
GO:0043022	ribosome binding	1.56e-02	1.00e+00	5.996	1	2	17
GO:0006611	protein export from nucleus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0031047	gene silencing by RNA	1.65e-02	1.00e+00	5.914	1	2	18
GO:0006378	mRNA polyadenylation	1.65e-02	1.00e+00	5.914	1	3	18
GO:0015631	tubulin binding	1.83e-02	1.00e+00	5.762	1	1	20
GO:0071346	cellular response to interferon-gamma	1.83e-02	1.00e+00	5.762	1	2	20
GO:0072686	mitotic spindle	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034660	ncRNA metabolic process	1.83e-02	1.00e+00	5.762	1	1	20
GO:0031647	regulation of protein stability	1.92e-02	1.00e+00	5.691	1	2	21
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	1.92e-02	1.00e+00	5.691	1	2	21
GO:0006606	protein import into nucleus	2.01e-02	1.00e+00	5.624	1	3	22
GO:0000387	spliceosomal snRNP assembly	2.01e-02	1.00e+00	5.624	1	1	22
GO:0034605	cellular response to heat	2.01e-02	1.00e+00	5.624	1	1	22
GO:0007162	negative regulation of cell adhesion	2.19e-02	1.00e+00	5.499	1	2	24
GO:0006370	7-methylguanosine mRNA capping	2.19e-02	1.00e+00	5.499	1	5	24
GO:0016592	mediator complex	2.28e-02	1.00e+00	5.440	1	6	25
GO:0010827	regulation of glucose transport	2.28e-02	1.00e+00	5.440	1	7	25
GO:0007094	mitotic spindle assembly checkpoint	2.28e-02	1.00e+00	5.440	1	4	25
GO:0031072	heat shock protein binding	2.55e-02	1.00e+00	5.276	1	1	28
GO:0008094	DNA-dependent ATPase activity	2.64e-02	1.00e+00	5.225	1	6	29
GO:0008026	ATP-dependent helicase activity	2.64e-02	1.00e+00	5.225	1	3	29
GO:0005778	peroxisomal membrane	2.64e-02	1.00e+00	5.225	1	3	29
GO:0006446	regulation of translational initiation	2.64e-02	1.00e+00	5.225	1	2	29
GO:0019898	extrinsic component of membrane	2.73e-02	1.00e+00	5.177	1	1	30
GO:0007077	mitotic nuclear envelope disassembly	2.91e-02	1.00e+00	5.083	1	9	32
GO:0017148	negative regulation of translation	3.00e-02	1.00e+00	5.039	1	5	33
GO:0050434	positive regulation of viral transcription	3.18e-02	1.00e+00	4.954	1	5	35
GO:0008645	hexose transport	3.27e-02	1.00e+00	4.914	1	8	36
GO:0019827	stem cell maintenance	3.54e-02	1.00e+00	4.798	1	4	39
GO:0006396	RNA processing	3.63e-02	1.00e+00	4.762	1	4	40
GO:0006366	transcription from RNA polymerase II promoter	3.72e-02	1.00e+00	2.670	2	23	341
GO:0015758	glucose transport	4.34e-02	1.00e+00	4.499	1	8	48
GO:0000151	ubiquitin ligase complex	4.34e-02	1.00e+00	4.499	1	4	48
GO:0005777	peroxisome	4.52e-02	1.00e+00	4.440	1	2	50
GO:0005643	nuclear pore	4.61e-02	1.00e+00	4.411	1	12	51
GO:0006368	transcription elongation from RNA polymerase II promoter	4.69e-02	1.00e+00	4.383	1	8	52
GO:0000776	kinetochore	4.96e-02	1.00e+00	4.302	1	8	55
GO:0005681	spliceosomal complex	4.96e-02	1.00e+00	4.302	1	8	55
GO:0003729	mRNA binding	5.13e-02	1.00e+00	4.251	1	4	57
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	5	61
GO:0016337	single organismal cell-cell adhesion	5.57e-02	1.00e+00	4.129	1	3	62
GO:0006415	translational termination	5.66e-02	1.00e+00	4.106	1	2	63
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	5	74
GO:0005215	transporter activity	7.31e-02	1.00e+00	3.726	1	5	82
GO:0005635	nuclear envelope	7.40e-02	1.00e+00	3.708	1	6	83
GO:0044255	cellular lipid metabolic process	7.91e-02	1.00e+00	3.608	1	2	89
GO:0030335	positive regulation of cell migration	8.94e-02	1.00e+00	3.425	1	2	101
GO:0016020	membrane	8.94e-02	1.00e+00	1.431	3	56	1207
GO:0006397	mRNA processing	9.70e-02	1.00e+00	3.302	1	12	110
GO:0031965	nuclear membrane	1.14e-01	1.00e+00	3.061	1	8	130
GO:0005739	mitochondrion	1.19e-01	1.00e+00	1.719	2	32	659
GO:0016874	ligase activity	1.27e-01	1.00e+00	2.894	1	11	146
GO:0006355	regulation of transcription, DNA-templated	1.37e-01	1.00e+00	1.602	2	31	715
GO:0008270	zinc ion binding	1.41e-01	1.00e+00	1.578	2	39	727
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	9	165
GO:0019221	cytokine-mediated signaling pathway	1.48e-01	1.00e+00	2.657	1	10	172
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	13	176
GO:0006412	translation	1.53e-01	1.00e+00	2.608	1	12	178
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	17	179
GO:0003779	actin binding	1.53e-01	1.00e+00	2.600	1	3	179
GO:0005975	carbohydrate metabolic process	1.59e-01	1.00e+00	2.544	1	10	186
GO:0016567	protein ubiquitination	1.61e-01	1.00e+00	2.529	1	14	188
GO:0044281	small molecule metabolic process	1.79e-01	1.00e+00	1.362	2	35	844
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	8	218
GO:0006200	ATP catabolic process	1.85e-01	1.00e+00	2.309	1	13	219
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	127	2633
GO:0003682	chromatin binding	2.10e-01	1.00e+00	2.106	1	15	252
GO:0055114	oxidation-reduction process	2.51e-01	1.00e+00	1.817	1	9	308
GO:0000278	mitotic cell cycle	2.55e-01	1.00e+00	1.789	1	28	314
GO:0055085	transmembrane transport	2.66e-01	1.00e+00	1.722	1	13	329
GO:0044267	cellular protein metabolic process	2.81e-01	1.00e+00	1.624	1	14	352
GO:0042802	identical protein binding	2.83e-01	1.00e+00	1.616	1	15	354
GO:0005783	endoplasmic reticulum	3.01e-01	1.00e+00	1.510	1	12	381
GO:0005730	nucleolus	3.11e-01	1.00e+00	0.834	2	74	1217
GO:0042803	protein homodimerization activity	3.32e-01	1.00e+00	1.342	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.50e-01	1.00e+00	1.251	1	29	456
GO:0005829	cytosol	5.11e-01	1.00e+00	0.280	2	88	1787
GO:0005524	ATP binding	5.78e-01	1.00e+00	0.283	1	37	892
GO:0046872	metal ion binding	5.96e-01	1.00e+00	0.216	1	24	934
GO:0003677	DNA binding	6.01e-01	1.00e+00	0.196	1	52	947
GO:0005634	nucleus	6.21e-01	1.00e+00	0.004	3	158	3246
GO:0006351	transcription, DNA-templated	6.50e-01	1.00e+00	0.012	1	47	1076
GO:0005886	plasma membrane	8.37e-01	1.00e+00	-0.717	1	46	1784

chia-Fav

reg-snw-8458

Statistics

Genes (9)

Interactions (8)

Related GO terms (159)