reg-snw-84455

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.239	1.81e-07	3.67e-02	2.82e-02

chia-screen-data-Fav-reg-snw-84455 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
TDP1	55775	5	-1.669	2.428	52	-	-	-
KARS	3735	12	-1.759	2.428	123	TF	-	-
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
[ EFCAB7 ]	84455	1	-1.050	2.239	6	-	-	-
CENPQ	55166	20	-2.137	2.459	16	-	Yes	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
GTF3C3	9330	5	-1.450	2.428	62	TF	-	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
NR2C1	7181	1	-1.453	2.239	8	TF	-	-

Interactions (15)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NR2C1	7181	EFCAB7	84455	pd	>	reg.ITFP.txt: no annot
NR2C1	7181	CENPQ	55166	pd	>	reg.ITFP.txt: no annot
KARS	3735	GTF3C3	9330	pd	<>	reg.ITFP.txt: no annot
GTF3C3	9330	EFCAB7	84455	pd	>	reg.ITFP.txt: no annot
GTF3C3	9330	TDP1	55775	pd	>	reg.ITFP.txt: no annot
KARS	3735	PHB2	11331	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
KARS	3735	PHB	5245	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	TDP1	55775	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	KARS	3735	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
EIF2S2	8894	GTF3C3	9330	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot

Related GO terms (141)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	1.91e-06	1.86e-02	9.446	2	2	2
GO:0010467	gene expression	5.41e-05	5.28e-01	2.968	6	49	535
GO:0006479	protein methylation	1.04e-04	1.00e+00	6.987	2	2	11
GO:0003723	RNA binding	3.27e-04	1.00e+00	3.498	4	22	247
GO:0005654	nucleoplasm	8.19e-04	1.00e+00	2.256	6	68	876
GO:0005515	protein binding	1.09e-03	1.00e+00	1.021	12	198	4124
GO:0017005	3'-tyrosyl-DNA phosphodiesterase activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0016149	translation release factor activity, codon specific	1.43e-03	1.00e+00	9.446	1	1	1
GO:0006430	lysyl-tRNA aminoacylation	1.43e-03	1.00e+00	9.446	1	1	1
GO:0004824	lysine-tRNA ligase activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0008079	translation termination factor activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	2.87e-03	1.00e+00	8.446	1	1	2
GO:0015966	diadenosine tetraphosphate biosynthetic process	2.87e-03	1.00e+00	8.446	1	1	2
GO:0002176	male germ cell proliferation	2.87e-03	1.00e+00	8.446	1	1	2
GO:0042826	histone deacetylase binding	3.01e-03	1.00e+00	4.588	2	5	58
GO:0006415	translational termination	3.55e-03	1.00e+00	4.469	2	2	63
GO:0005850	eukaryotic translation initiation factor 2 complex	4.30e-03	1.00e+00	7.861	1	2	3
GO:0001649	osteoblast differentiation	4.86e-03	1.00e+00	4.237	2	5	74
GO:0097452	GAIT complex	5.72e-03	1.00e+00	7.446	1	2	4
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	5.72e-03	1.00e+00	7.446	1	1	4
GO:0006449	regulation of translational termination	5.72e-03	1.00e+00	7.446	1	1	4
GO:0000012	single strand break repair	5.72e-03	1.00e+00	7.446	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	5.72e-03	1.00e+00	7.446	1	1	4
GO:0030529	ribonucleoprotein complex	5.94e-03	1.00e+00	4.088	2	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.22e-03	1.00e+00	4.054	2	5	84
GO:0004521	endoribonuclease activity	7.15e-03	1.00e+00	7.124	1	1	5
GO:0042797	tRNA transcription from RNA polymerase III promoter	7.15e-03	1.00e+00	7.124	1	3	5
GO:0006398	histone mRNA 3'-end processing	7.15e-03	1.00e+00	7.124	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	7.15e-03	1.00e+00	7.124	1	2	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	7.15e-03	1.00e+00	7.124	1	1	5
GO:0060744	mammary gland branching involved in thelarche	7.15e-03	1.00e+00	7.124	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	7.15e-03	1.00e+00	7.124	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	7.15e-03	1.00e+00	7.124	1	1	5
GO:0000127	transcription factor TFIIIC complex	7.15e-03	1.00e+00	7.124	1	3	5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	7.15e-03	1.00e+00	7.124	1	3	5
GO:0050847	progesterone receptor signaling pathway	8.57e-03	1.00e+00	6.861	1	2	6
GO:0070937	CRD-mediated mRNA stability complex	8.57e-03	1.00e+00	6.861	1	2	6
GO:0008409	5'-3' exonuclease activity	1.00e-02	1.00e+00	6.639	1	2	7
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	1.00e-02	1.00e+00	6.639	1	2	7
GO:0010944	negative regulation of transcription by competitive promoter binding	1.14e-02	1.00e+00	6.446	1	1	8
GO:0010388	cullin deneddylation	1.14e-02	1.00e+00	6.446	1	4	8
GO:0006379	mRNA cleavage	1.28e-02	1.00e+00	6.276	1	2	9
GO:0071354	cellular response to interleukin-6	1.28e-02	1.00e+00	6.276	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.28e-02	1.00e+00	6.276	1	3	9
GO:0000398	mRNA splicing, via spliceosome	1.40e-02	1.00e+00	3.446	2	15	128
GO:0005095	GTPase inhibitor activity	1.43e-02	1.00e+00	6.124	1	1	10
GO:0008143	poly(A) binding	1.43e-02	1.00e+00	6.124	1	2	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.57e-02	1.00e+00	5.987	1	4	11
GO:0004527	exonuclease activity	1.71e-02	1.00e+00	5.861	1	4	12
GO:0060749	mammary gland alveolus development	1.85e-02	1.00e+00	5.746	1	1	13
GO:0016597	amino acid binding	1.99e-02	1.00e+00	5.639	1	1	14
GO:0016575	histone deacetylation	1.99e-02	1.00e+00	5.639	1	2	14
GO:0008135	translation factor activity, nucleic acid binding	2.13e-02	1.00e+00	5.539	1	4	15
GO:0000188	inactivation of MAPK activity	2.13e-02	1.00e+00	5.539	1	1	15
GO:0008380	RNA splicing	2.26e-02	1.00e+00	3.080	2	21	165
GO:0044822	poly(A) RNA binding	2.29e-02	1.00e+00	1.804	4	45	799
GO:0043022	ribosome binding	2.41e-02	1.00e+00	5.359	1	2	17
GO:0006378	mRNA polyadenylation	2.55e-02	1.00e+00	5.276	1	3	18
GO:0006412	translation	2.60e-02	1.00e+00	2.970	2	12	178
GO:0034080	CENP-A containing nucleosome assembly	2.83e-02	1.00e+00	5.124	1	2	20
GO:0071346	cellular response to interferon-gamma	2.83e-02	1.00e+00	5.124	1	2	20
GO:0071897	DNA biosynthetic process	2.83e-02	1.00e+00	5.124	1	2	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2.97e-02	1.00e+00	5.054	1	2	21
GO:0030331	estrogen receptor binding	3.11e-02	1.00e+00	4.987	1	2	22
GO:0005743	mitochondrial inner membrane	3.14e-02	1.00e+00	2.824	2	9	197
GO:0000049	tRNA binding	3.25e-02	1.00e+00	4.922	1	2	23
GO:0008180	COP9 signalosome	3.39e-02	1.00e+00	4.861	1	6	24
GO:0008033	tRNA processing	3.53e-02	1.00e+00	4.802	1	2	25
GO:0006418	tRNA aminoacylation for protein translation	4.08e-02	1.00e+00	4.588	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	4.08e-02	1.00e+00	4.588	1	6	29
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.36e-02	1.00e+00	4.492	1	6	31
GO:0045111	intermediate filament cytoskeleton	4.36e-02	1.00e+00	4.492	1	3	31
GO:0017148	negative regulation of translation	4.63e-02	1.00e+00	4.402	1	5	33
GO:0007254	JNK cascade	4.77e-02	1.00e+00	4.359	1	1	34
GO:0031124	mRNA 3'-end processing	4.91e-02	1.00e+00	4.317	1	4	35
GO:0003743	translation initiation factor activity	5.18e-02	1.00e+00	4.237	1	8	37
GO:0006369	termination of RNA polymerase II transcription	5.32e-02	1.00e+00	4.198	1	5	38
GO:0006396	RNA processing	5.59e-02	1.00e+00	4.124	1	4	40
GO:0000775	chromosome, centromeric region	5.72e-02	1.00e+00	4.088	1	6	41
GO:0003707	steroid hormone receptor activity	5.86e-02	1.00e+00	4.054	1	1	42
GO:0006406	mRNA export from nucleus	6.13e-02	1.00e+00	3.987	1	7	44
GO:0005739	mitochondrion	6.37e-02	1.00e+00	1.667	3	32	659
GO:0043401	steroid hormone mediated signaling pathway	6.54e-02	1.00e+00	3.891	1	1	47
GO:0006334	nucleosome assembly	7.07e-02	1.00e+00	3.774	1	4	51
GO:0006302	double-strand break repair	7.21e-02	1.00e+00	3.746	1	5	52
GO:0045892	negative regulation of transcription, DNA-templated	7.39e-02	1.00e+00	2.138	2	17	317
GO:0008584	male gonad development	7.87e-02	1.00e+00	3.613	1	1	57
GO:0003697	single-stranded DNA binding	7.87e-02	1.00e+00	3.613	1	4	57
GO:0071013	catalytic step 2 spliceosome	8.40e-02	1.00e+00	3.515	1	5	61
GO:0044267	cellular protein metabolic process	8.86e-02	1.00e+00	1.987	2	14	352
GO:0030308	negative regulation of cell growth	9.59e-02	1.00e+00	3.317	1	3	70
GO:0016363	nuclear matrix	9.98e-02	1.00e+00	3.256	1	10	73
GO:0015630	microtubule cytoskeleton	1.02e-01	1.00e+00	3.217	1	5	75
GO:0016605	PML body	1.08e-01	1.00e+00	3.142	1	5	79
GO:0003690	double-stranded DNA binding	1.13e-01	1.00e+00	3.071	1	6	83
GO:0016032	viral process	1.23e-01	1.00e+00	1.705	2	30	428
GO:0006413	translational initiation	1.33e-01	1.00e+00	2.817	1	6	99
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.37e-01	1.00e+00	1.613	2	29	456
GO:0046872	metal ion binding	1.44e-01	1.00e+00	1.164	3	24	934
GO:0005634	nucleus	1.48e-01	1.00e+00	0.589	7	158	3246
GO:0005737	cytoplasm	1.49e-01	1.00e+00	0.669	6	127	2633
GO:0042981	regulation of apoptotic process	1.49e-01	1.00e+00	2.639	1	4	112
GO:0007049	cell cycle	1.53e-01	1.00e+00	2.601	1	8	115
GO:0004872	receptor activity	1.54e-01	1.00e+00	2.588	1	4	116
GO:0003924	GTPase activity	1.58e-01	1.00e+00	2.551	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	1.65e-01	1.00e+00	2.480	1	4	125
GO:0006184	GTP catabolic process	1.71e-01	1.00e+00	2.424	1	7	130
GO:0005759	mitochondrial matrix	1.82e-01	1.00e+00	2.327	1	7	139
GO:0044212	transcription regulatory region DNA binding	1.87e-01	1.00e+00	2.286	1	13	143
GO:0005622	intracellular	1.89e-01	1.00e+00	2.266	1	2	145
GO:0001701	in utero embryonic development	2.00e-01	1.00e+00	2.179	1	7	154
GO:0006367	transcription initiation from RNA polymerase II promoter	2.08e-01	1.00e+00	2.115	1	18	161
GO:0016071	mRNA metabolic process	2.18e-01	1.00e+00	2.037	1	10	170
GO:0000166	nucleotide binding	2.25e-01	1.00e+00	1.987	1	13	176
GO:0016070	RNA metabolic process	2.38e-01	1.00e+00	1.891	1	10	188
GO:0005829	cytosol	2.45e-01	1.00e+00	0.643	4	88	1787
GO:0005525	GTP binding	2.48e-01	1.00e+00	1.824	1	12	197
GO:0006281	DNA repair	2.55e-01	1.00e+00	1.781	1	24	203
GO:0043234	protein complex	2.63e-01	1.00e+00	1.732	1	13	210
GO:0019899	enzyme binding	2.63e-01	1.00e+00	1.732	1	7	210
GO:0043565	sequence-specific DNA binding	3.30e-01	1.00e+00	1.343	1	8	275
GO:0008285	negative regulation of cell proliferation	3.32e-01	1.00e+00	1.332	1	11	277
GO:0000278	mitotic cell cycle	3.67e-01	1.00e+00	1.151	1	28	314
GO:0006366	transcription from RNA polymerase II promoter	3.92e-01	1.00e+00	1.032	1	23	341
GO:0003677	DNA binding	4.00e-01	1.00e+00	0.559	2	52	947
GO:0005509	calcium ion binding	4.01e-01	1.00e+00	0.991	1	9	351
GO:0045893	positive regulation of transcription, DNA-templated	4.24e-01	1.00e+00	0.888	1	21	377
GO:0005783	endoplasmic reticulum	4.27e-01	1.00e+00	0.872	1	12	381
GO:0042803	protein homodimerization activity	4.66e-01	1.00e+00	0.705	1	13	428
GO:0006351	transcription, DNA-templated	4.67e-01	1.00e+00	0.375	2	47	1076
GO:0016020	membrane	5.31e-01	1.00e+00	0.209	2	56	1207
GO:0005887	integral component of plasma membrane	5.73e-01	1.00e+00	0.279	1	8	575
GO:0003700	sequence-specific DNA binding transcription factor activity	5.77e-01	1.00e+00	0.261	1	22	582
GO:0007165	signal transduction	6.00e-01	1.00e+00	0.175	1	24	618
GO:0005576	extracellular region	6.27e-01	1.00e+00	0.073	1	15	663
GO:0006355	regulation of transcription, DNA-templated	6.55e-01	1.00e+00	-0.036	1	31	715
GO:0008270	zinc ion binding	6.62e-01	1.00e+00	-0.060	1	39	727
GO:0070062	extracellular vesicular exosome	7.09e-01	1.00e+00	-0.234	2	51	1641
GO:0005524	ATP binding	7.39e-01	1.00e+00	-0.355	1	37	892
GO:0005730	nucleolus	8.45e-01	1.00e+00	-0.803	1	74	1217
GO:0005886	plasma membrane	9.41e-01	1.00e+00	-1.355	1	46	1784

chia-Fav

reg-snw-84455

Statistics

Genes (14)

Interactions (15)

Related GO terms (141)