reg-snw-80830

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.230 2.02e-07 3.89e-02 2.97e-02
chia-screen-data-Fav-reg-snw-80830 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
PHB 5245 82-2.7432.68936-YesYes
VDAC2 7417 1-1.8922.2308---
KIAA1551 55196 6-1.8522.36935---
ENPP7 339221 10-2.5692.3696-YesYes
APC 324 5-2.2932.30831TFYes-
KLHL8 57563 4-1.9932.30830TF--
FBXO22 26263 36-1.7392.459208TF--
DTX3L 151636 2-1.9072.30813TF--
FOXJ3 22887 15-2.4072.36987TFYesYes
NCBP1 4686 41-2.5102.45944-YesYes
EIF2S2 8894 40-2.9992.45922-YesYes
COPS3 8533 8-1.8732.43579TF--
REXO1 57455 12-2.3032.369130TFYes-
[ APOL6 ] 80830 1-0.2762.2301---
EIF2B3 8891 8-2.5462.4354-YesYes
GPS1 2873 86-3.6212.68936TFYesYes
POLH 5429 36-2.5862.45924-YesYes
NCOA2 10499 4-1.7862.32695TF--

Interactions (21)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
FOXJ3 22887 REXO1 57455 pd <> reg.ITFP.txt: no annot
NCBP1 4686 FBXO22 26263 pd < reg.ITFP.txt: no annot
APC 324 FOXJ3 22887 pd <> reg.ITFP.txt: no annot
FOXJ3 22887 KIAA1551 55196 pd > reg.ITFP.txt: no annot
KIAA1551 55196 KLHL8 57563 pd < reg.ITFP.txt: no annot
KIAA1551 55196 DTX3L 151636 pd < reg.ITFP.txt: no annot
APC 324 KIAA1551 55196 pd > reg.ITFP.txt: no annot
VDAC2 7417 COPS3 8533 pd < reg.ITFP.txt: no annot
APOL6 80830 DTX3L 151636 pd < reg.ITFP.txt: no annot
VDAC2 7417 DTX3L 151636 pd < reg.ITFP.txt: no annot
EIF2S2 8894 FBXO22 26263 pd < reg.ITFP.txt: no annot
FBXO22 26263 KIAA1551 55196 pd > reg.ITFP.txt: no annot
FBXO22 26263 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot
REXO1 57455 ENPP7 339221 pd > reg.ITFP.txt: no annot
PHB 5245 FBXO22 26263 pd < reg.ITFP.txt: no annot
NCOA2 10499 KIAA1551 55196 pd > reg.ITFP.txt: no annot
POLH 5429 FBXO22 26263 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
COPS3 8533 EIF2B3 8891 pd > reg.ITFP.txt: no annot
APC 324 NCOA2 10499 pd <> reg.ITFP.txt: no annot
KIAA1551 55196 REXO1 57455 pd < reg.ITFP.txt: no annot

Related GO terms (223)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0010388cullin deneddylation9.97e-059.74e-017.005248
GO:0008135translation factor activity, nucleic acid binding3.71e-041.00e+006.0992415
GO:0008180COP9 signalosome9.65e-041.00e+005.4212624
GO:0051171regulation of nitrogen compound metabolic process1.95e-031.00e+009.005111
GO:0042483negative regulation of odontogenesis1.95e-031.00e+009.005111
GO:0032272negative regulation of protein polymerization1.95e-031.00e+009.005111
GO:0003743translation initiation factor activity2.29e-031.00e+004.7962837
GO:0048742regulation of skeletal muscle fiber development3.89e-031.00e+008.005112
GO:0051716cellular response to stimulus3.89e-031.00e+008.005112
GO:0006684sphingomyelin metabolic process3.89e-031.00e+008.005112
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic process3.89e-031.00e+008.005112
GO:0005846nuclear cap binding complex3.89e-031.00e+008.005112
GO:0002176male germ cell proliferation3.89e-031.00e+008.005112
GO:0009798axis specification3.89e-031.00e+008.005112
GO:0005850eukaryotic translation initiation factor 2 complex5.83e-031.00e+007.421123
GO:0030375thyroid hormone receptor coactivator activity5.83e-031.00e+007.421113
GO:0004767sphingomyelin phosphodiesterase activity5.83e-031.00e+007.421113
GO:0019887protein kinase regulator activity5.83e-031.00e+007.421123
GO:0045292mRNA cis splicing, via spliceosome7.76e-031.00e+007.005114
GO:0031442positive regulation of mRNA 3'-end processing7.76e-031.00e+007.005114
GO:0006290pyrimidine dimer repair7.76e-031.00e+007.005124
GO:0032057negative regulation of translational initiation in response to stress7.76e-031.00e+007.005114
GO:0005851eukaryotic translation initiation factor 2B complex7.76e-031.00e+007.005124
GO:0008308voltage-gated anion channel activity7.76e-031.00e+007.005114
GO:0016779nucleotidyltransferase activity7.76e-031.00e+007.005114
GO:0007091metaphase/anaphase transition of mitotic cell cycle9.69e-031.00e+006.684125
GO:0015288porin activity9.69e-031.00e+006.684115
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland development9.69e-031.00e+006.684115
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic process9.69e-031.00e+006.684115
GO:0031274positive regulation of pseudopodium assembly9.69e-031.00e+006.684115
GO:0006282regulation of DNA repair9.69e-031.00e+006.684125
GO:2000323negative regulation of glucocorticoid receptor signaling pathway9.69e-031.00e+006.684115
GO:0030858positive regulation of epithelial cell differentiation1.16e-021.00e+006.421116
GO:0050847progesterone receptor signaling pathway1.16e-021.00e+006.421126
GO:0006820anion transport1.16e-021.00e+006.421116
GO:0045670regulation of osteoclast differentiation1.35e-021.00e+006.198117
GO:0000731DNA synthesis involved in DNA repair1.35e-021.00e+006.198117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.35e-021.00e+006.198117
GO:0006301postreplication repair1.35e-021.00e+006.198127
GO:0000339RNA cap binding1.35e-021.00e+006.198117
GO:0030877beta-catenin destruction complex1.35e-021.00e+006.198117
GO:2000273positive regulation of receptor activity1.55e-021.00e+006.005118
GO:0031116positive regulation of microtubule polymerization1.55e-021.00e+006.005118
GO:0005845mRNA cap binding complex1.55e-021.00e+006.005118
GO:0045667regulation of osteoblast differentiation1.55e-021.00e+006.005128
GO:0031122cytoplasmic microtubule organization1.55e-021.00e+006.005118
GO:0010944negative regulation of transcription by competitive promoter binding1.55e-021.00e+006.005118
GO:0010390histone monoubiquitination1.55e-021.00e+006.005128
GO:0046930pore complex1.55e-021.00e+006.005118
GO:0008285negative regulation of cell proliferation1.56e-021.00e+002.477311277
GO:0006413translational initiation1.56e-021.00e+003.3762699
GO:0045295gamma-catenin binding1.74e-021.00e+005.836119
GO:0010225response to UV-C1.74e-021.00e+005.836129
GO:0032886regulation of microtubule-based process1.74e-021.00e+005.836119
GO:0044295axonal growth cone1.74e-021.00e+005.836119
GO:0006379mRNA cleavage1.74e-021.00e+005.836129
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process1.74e-021.00e+005.836129
GO:0071354cellular response to interleukin-61.74e-021.00e+005.836119
GO:0005095GTPase inhibitor activity1.93e-021.00e+005.6841110
GO:0009416response to light stimulus1.93e-021.00e+005.6841110
GO:0043409negative regulation of MAPK cascade1.93e-021.00e+005.6841110
GO:0060766negative regulation of androgen receptor signaling pathway2.12e-021.00e+005.5461411
GO:0051010microtubule plus-end binding2.12e-021.00e+005.5461211
GO:0007026negative regulation of microtubule depolymerization2.12e-021.00e+005.5461211
GO:0046716muscle cell cellular homeostasis2.12e-021.00e+005.5461111
GO:0008334histone mRNA metabolic process2.12e-021.00e+005.5461111
GO:0006974cellular response to DNA damage stimulus2.27e-021.00e+003.087211121
GO:0051276chromosome organization2.31e-021.00e+005.4211212
GO:0004527exonuclease activity2.31e-021.00e+005.4211412
GO:0035371microtubule plus-end2.50e-021.00e+005.3051213
GO:0010906regulation of glucose metabolic process2.50e-021.00e+005.3051113
GO:0008156negative regulation of DNA replication2.50e-021.00e+005.3051113
GO:0044070regulation of anion transport2.69e-021.00e+005.1981114
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity2.69e-021.00e+005.1981314
GO:0016575histone deacetylation2.69e-021.00e+005.1981214
GO:0016922ligand-dependent nuclear receptor binding2.88e-021.00e+005.0991215
GO:0000188inactivation of MAPK activity2.88e-021.00e+005.0991115
GO:0014003oligodendrocyte development2.88e-021.00e+005.0991115
GO:0000281mitotic cytokinesis2.88e-021.00e+005.0991315
GO:0031463Cul3-RING ubiquitin ligase complex3.07e-021.00e+005.0051116
GO:0003887DNA-directed DNA polymerase activity3.07e-021.00e+005.0051216
GO:0009954proximal/distal pattern formation3.26e-021.00e+004.9181217
GO:0009953dorsal/ventral pattern formation3.45e-021.00e+004.8361218
GO:0031047gene silencing by RNA3.45e-021.00e+004.8361218
GO:2001243negative regulation of intrinsic apoptotic signaling pathway3.45e-021.00e+004.8361118
GO:0035257nuclear hormone receptor binding3.45e-021.00e+004.8361118
GO:0001701in utero embryonic development3.55e-021.00e+002.73927154
GO:0016573histone acetylation3.64e-021.00e+004.7581119
GO:0006913nucleocytoplasmic transport3.82e-021.00e+004.6841220
GO:0045296cadherin binding3.82e-021.00e+004.6841220
GO:0071897DNA biosynthetic process3.82e-021.00e+004.6841220
GO:0034660ncRNA metabolic process3.82e-021.00e+004.6841120
GO:0001942hair follicle development4.01e-021.00e+004.6131221
GO:0051781positive regulation of cell division4.20e-021.00e+004.5461222
GO:0000387spliceosomal snRNP assembly4.20e-021.00e+004.5461122
GO:0006687glycosphingolipid metabolic process4.20e-021.00e+004.5461122
GO:0005737cytoplasm4.54e-021.00e+000.81391272633
GO:0005881cytoplasmic microtubule4.57e-021.00e+004.4211324
GO:00063707-methylguanosine mRNA capping4.57e-021.00e+004.4211524
GO:0006412translation4.61e-021.00e+002.530212178
GO:0004842ubiquitin-protein transferase activity4.66e-021.00e+002.522217179
GO:0005902microvillus4.76e-021.00e+004.3621125
GO:0048538thymus development4.76e-021.00e+004.3621125
GO:0005913cell-cell adherens junction4.76e-021.00e+004.3621325
GO:0007094mitotic spindle assembly checkpoint4.76e-021.00e+004.3621425
GO:0009267cellular response to starvation4.94e-021.00e+004.3051126
GO:0033077T cell differentiation in thymus4.94e-021.00e+004.3051226
GO:0045785positive regulation of cell adhesion5.50e-021.00e+004.1471329
GO:0070830tight junction assembly5.50e-021.00e+004.1471129
GO:0006446regulation of translational initiation5.50e-021.00e+004.1471229
GO:0005743mitochondrial inner membrane5.53e-021.00e+002.38329197
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity5.68e-021.00e+004.0991330
GO:0004402histone acetyltransferase activity5.68e-021.00e+004.0991330
GO:0009408response to heat5.87e-021.00e+004.0511131
GO:0042645mitochondrial nucleoid5.87e-021.00e+004.0511131
GO:0090305nucleic acid phosphodiester bond hydrolysis5.87e-021.00e+004.0511631
GO:0016328lateral plasma membrane5.87e-021.00e+004.0511231
GO:0006921cellular component disassembly involved in execution phase of apoptosis5.87e-021.00e+004.0511131
GO:0042157lipoprotein metabolic process6.05e-021.00e+004.0051432
GO:0035019somatic stem cell maintenance6.05e-021.00e+004.0051332
GO:0005634nucleus6.35e-021.00e+000.663101583246
GO:0006869lipid transport6.42e-021.00e+003.9181234
GO:0007254JNK cascade6.42e-021.00e+003.9181134
GO:0060041retina development in camera-type eye6.42e-021.00e+003.9181134
GO:0045732positive regulation of protein catabolic process6.42e-021.00e+003.9181134
GO:0050434positive regulation of viral transcription6.60e-021.00e+003.8761535
GO:0031124mRNA 3'-end processing6.60e-021.00e+003.8761435
GO:0043434response to peptide hormone6.78e-021.00e+003.8361136
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process6.97e-021.00e+003.7961237
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process7.15e-021.00e+003.7581438
GO:0006665sphingolipid metabolic process7.15e-021.00e+003.7581138
GO:0006369termination of RNA polymerase II transcription7.15e-021.00e+003.7581538
GO:0003684damaged DNA binding7.69e-021.00e+003.6481141
GO:0005085guanyl-nucleotide exchange factor activity8.05e-021.00e+003.5791243
GO:0003723RNA binding8.22e-021.00e+002.057222247
GO:0006406mRNA export from nucleus8.23e-021.00e+003.5461744
GO:0010467gene expression8.25e-021.00e+001.527349535
GO:0009749response to glucose8.41e-021.00e+003.5141145
GO:0007409axonogenesis8.41e-021.00e+003.5141245
GO:0008013beta-catenin binding8.41e-021.00e+003.5141345
GO:0005654nucleoplasm8.43e-021.00e+001.231468876
GO:0032587ruffle membrane9.30e-021.00e+003.3621350
GO:0060070canonical Wnt signaling pathway9.48e-021.00e+003.3331151
GO:0001822kidney development9.66e-021.00e+003.3051352
GO:0006368transcription elongation from RNA polymerase II promoter9.66e-021.00e+003.3051852
GO:0006302double-strand break repair9.66e-021.00e+003.3051552
GO:0042393histone binding1.00e-011.00e+003.2511354
GO:0000776kinetochore1.02e-011.00e+003.2241855
GO:0008584male gonad development1.05e-011.00e+003.1731157
GO:0042826histone deacetylase binding1.07e-011.00e+003.1471558
GO:0090090negative regulation of canonical Wnt signaling pathway1.09e-011.00e+003.1231559
GO:0009952anterior/posterior pattern specification1.11e-011.00e+003.0991360
GO:0006464cellular protein modification process1.12e-011.00e+003.0751461
GO:0007165signal transduction1.15e-011.00e+001.319324618
GO:0030018Z disc1.18e-011.00e+003.0051364
GO:0005923tight junction1.18e-011.00e+003.0051264
GO:0003676nucleic acid binding1.21e-011.00e+002.9611466
GO:0005515protein binding1.25e-011.00e+000.455111984124
GO:0030308negative regulation of cell growth1.28e-011.00e+002.8761370
GO:0005739mitochondrion1.33e-011.00e+001.226332659
GO:0008289lipid binding1.33e-011.00e+002.8161473
GO:0001649osteoblast differentiation1.35e-011.00e+002.7961574
GO:0005741mitochondrial outer membrane1.43e-011.00e+002.7021279
GO:0030529ribonucleoprotein complex1.48e-011.00e+002.6481582
GO:0044267cellular protein metabolic process1.48e-011.00e+001.546214352
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.52e-011.00e+002.6131584
GO:0030027lamellipodium1.58e-011.00e+002.5461388
GO:0006355regulation of transcription, DNA-templated1.58e-011.00e+001.109331715
GO:0044255cellular lipid metabolic process1.60e-011.00e+002.5301289
GO:0006461protein complex assembly1.63e-011.00e+002.4981291
GO:0000209protein polyubiquitination1.65e-011.00e+002.4821692
GO:0006511ubiquitin-dependent protein catabolic process1.65e-011.00e+002.4821692
GO:0007050cell cycle arrest1.65e-011.00e+002.4821492
GO:0006260DNA replication1.68e-011.00e+002.4511994
GO:0046983protein dimerization activity1.68e-011.00e+002.4511294
GO:0016477cell migration1.71e-011.00e+002.4211396
GO:0008017microtubule binding1.73e-011.00e+002.4061997
GO:0030335positive regulation of cell migration1.79e-011.00e+002.34712101
GO:0043547positive regulation of GTPase activity1.97e-011.00e+002.19812112
GO:0042981regulation of apoptotic process1.97e-011.00e+002.19814112
GO:0007049cell cycle2.02e-011.00e+002.16018115
GO:0005730nucleolus2.05e-011.00e+000.7564741217
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.22e-011.00e+001.173229456
GO:0000398mRNA splicing, via spliceosome2.22e-011.00e+002.005115128
GO:0044212transcription regulatory region DNA binding2.45e-011.00e+001.846113143
GO:0016874ligase activity2.49e-011.00e+001.816111146
GO:0004871signal transducer activity2.52e-011.00e+001.79614148
GO:0008380RNA splicing2.77e-011.00e+001.639121165
GO:0016071mRNA metabolic process2.84e-011.00e+001.596110170
GO:0000166nucleotide binding2.92e-011.00e+001.546113176
GO:0003713transcription coactivator activity3.04e-011.00e+001.482121184
GO:0016567protein ubiquitination3.09e-011.00e+001.451114188
GO:0016070RNA metabolic process3.09e-011.00e+001.451110188
GO:0043065positive regulation of apoptotic process3.28e-011.00e+001.34717202
GO:0006281DNA repair3.29e-011.00e+001.340124203
GO:0008134transcription factor binding3.37e-011.00e+001.298110209
GO:0019899enzyme binding3.39e-011.00e+001.29117210
GO:0005813centrosome3.48e-011.00e+001.244110217
GO:0019901protein kinase binding3.67e-011.00e+001.14718232
GO:0007155cell adhesion3.82e-011.00e+001.07518244
GO:0003682chromatin binding3.92e-011.00e+001.028115252
GO:0043565sequence-specific DNA binding4.19e-011.00e+000.90218275
GO:0045892negative regulation of transcription, DNA-templated4.66e-011.00e+000.697117317
GO:0044822poly(A) RNA binding4.68e-011.00e+000.363245799
GO:0005829cytosol4.69e-011.00e+000.2024881787
GO:0055085transmembrane transport4.79e-011.00e+000.644113329
GO:0006366transcription from RNA polymerase II promoter4.91e-011.00e+000.592123341
GO:0044281small molecule metabolic process4.98e-011.00e+000.284235844
GO:0045893positive regulation of transcription, DNA-templated5.27e-011.00e+000.447121377
GO:0046872metal ion binding5.55e-011.00e+000.138224934
GO:0006915apoptotic process5.59e-011.00e+000.322115411
GO:0005794Golgi apparatus5.62e-011.00e+000.30916415
GO:0016032viral process5.74e-011.00e+000.264130428
GO:0006351transcription, DNA-templated6.35e-011.00e+00-0.0662471076
GO:0005887integral component of plasma membrane6.85e-011.00e+00-0.16218575
GO:0003700sequence-specific DNA binding transcription factor activity6.89e-011.00e+00-0.179122582
GO:0016020membrane7.00e-011.00e+00-0.2322561207
GO:0005886plasma membrane7.02e-011.00e+00-0.2103461784
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.27e-011.00e+00-0.325129644
GO:0005576extracellular region7.37e-011.00e+00-0.367115663
GO:0008270zinc ion binding7.70e-011.00e+00-0.500139727
GO:0070062extracellular vesicular exosome8.54e-011.00e+00-0.6752511641
GO:0016021integral component of membrane9.61e-011.00e+00-1.5701191526