reg-snw-7334

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.284	1.05e-07	2.75e-02	2.15e-02

chia-screen-data-Fav-reg-snw-7334 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
APLP2	334	15	-2.732	2.389	4	-	Yes	Yes
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GTF2A2	2958	9	-1.938	2.377	41	TF	-	-
[ UBE2N ]	7334	1	-1.692	2.284	31	-	-	-
SFPQ	6421	15	-2.051	2.389	142	TF	Yes	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
APLP2	334	SFPQ	6421	pd	<	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
SFPQ	6421	UBE2N	7334	pd	>	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GTF2A2	2958	UBE2N	7334	pd	>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
POLR2E	5434	UBE2N	7334	pd	>	reg.ITFP.txt: no annot

Related GO terms (178)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0008380	RNA splicing	3.69e-04	1.00e+00	4.302	3	21	165
GO:0010467	gene expression	9.00e-04	1.00e+00	3.020	4	49	535
GO:0004832	valine-tRNA ligase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0061383	trabecula morphogenesis	9.22e-04	1.00e+00	10.083	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0033182	regulation of histone ubiquitination	9.22e-04	1.00e+00	10.083	1	1	1
GO:0008175	tRNA methyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0035370	UBC13-UEV1A complex	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006438	valyl-tRNA aminoacylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0031058	positive regulation of histone modification	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006368	transcription elongation from RNA polymerase II promoter	9.78e-04	1.00e+00	5.383	2	8	52
GO:0033688	regulation of osteoblast proliferation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0031372	UBC13-MMS2 complex	1.84e-03	1.00e+00	9.083	1	1	2
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.84e-03	1.00e+00	9.083	1	1	2
GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	2.76e-03	1.00e+00	8.499	1	1	3
GO:0046914	transition metal ion binding	2.76e-03	1.00e+00	8.499	1	1	3
GO:0016574	histone ubiquitination	3.68e-03	1.00e+00	8.083	1	1	4
GO:0036089	cleavage furrow formation	3.68e-03	1.00e+00	8.083	1	1	4
GO:0007176	regulation of epidermal growth factor-activated receptor activity	3.68e-03	1.00e+00	8.083	1	1	4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	4.15e-03	1.00e+00	4.329	2	2	108
GO:0038027	apolipoprotein A-I-mediated signaling pathway	4.60e-03	1.00e+00	7.762	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.60e-03	1.00e+00	7.762	1	2	5
GO:0043931	ossification involved in bone maturation	4.60e-03	1.00e+00	7.762	1	1	5
GO:0005672	transcription factor TFIIA complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0006282	regulation of DNA repair	4.60e-03	1.00e+00	7.762	1	2	5
GO:0002161	aminoacyl-tRNA editing activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000729	DNA double-strand break processing	4.60e-03	1.00e+00	7.762	1	2	5
GO:0042382	paraspeckles	4.60e-03	1.00e+00	7.762	1	3	5
GO:0002181	cytoplasmic translation	5.52e-03	1.00e+00	7.499	1	1	6
GO:0001055	RNA polymerase II activity	5.52e-03	1.00e+00	7.499	1	3	6
GO:0042754	negative regulation of circadian rhythm	5.52e-03	1.00e+00	7.499	1	2	6
GO:0043297	apical junction assembly	5.52e-03	1.00e+00	7.499	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	5.52e-03	1.00e+00	7.499	1	2	6
GO:0005654	nucleoplasm	5.61e-03	1.00e+00	2.309	4	68	876
GO:0016032	viral process	5.76e-03	1.00e+00	2.927	3	30	428
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	15	128
GO:0006301	postreplication repair	6.44e-03	1.00e+00	7.276	1	2	7
GO:0007617	mating behavior	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000380	alternative mRNA splicing, via spliceosome	6.44e-03	1.00e+00	7.276	1	2	7
GO:0006878	cellular copper ion homeostasis	7.35e-03	1.00e+00	7.083	1	1	8
GO:0090307	spindle assembly involved in mitosis	7.35e-03	1.00e+00	7.083	1	2	8
GO:0006450	regulation of translational fidelity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0043296	apical junction complex	7.35e-03	1.00e+00	7.083	1	1	8
GO:0006367	transcription initiation from RNA polymerase II promoter	9.01e-03	1.00e+00	3.753	2	18	161
GO:0001967	suckling behavior	9.18e-03	1.00e+00	6.762	1	4	10
GO:0005736	DNA-directed RNA polymerase I complex	9.18e-03	1.00e+00	6.762	1	4	10
GO:0050919	negative chemotaxis	9.18e-03	1.00e+00	6.762	1	1	10
GO:0001054	RNA polymerase I activity	9.18e-03	1.00e+00	6.762	1	4	10
GO:0017025	TBP-class protein binding	1.10e-02	1.00e+00	6.499	1	1	12
GO:0050772	positive regulation of axonogenesis	1.19e-02	1.00e+00	6.383	1	2	13
GO:0050770	regulation of axonogenesis	1.19e-02	1.00e+00	6.383	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.19e-02	1.00e+00	6.383	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.19e-02	1.00e+00	6.383	1	3	13
GO:0001056	RNA polymerase III activity	1.19e-02	1.00e+00	6.383	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.19e-02	1.00e+00	6.383	1	1	13
GO:0051443	positive regulation of ubiquitin-protein transferase activity	1.28e-02	1.00e+00	6.276	1	2	14
GO:0006386	termination of RNA polymerase III transcription	1.28e-02	1.00e+00	6.276	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.28e-02	1.00e+00	6.276	1	3	14
GO:0050771	negative regulation of axonogenesis	1.28e-02	1.00e+00	6.276	1	2	14
GO:0043393	regulation of protein binding	1.28e-02	1.00e+00	6.276	1	2	14
GO:0070932	histone H3 deacetylation	1.37e-02	1.00e+00	6.177	1	2	15
GO:0006281	DNA repair	1.41e-02	1.00e+00	3.418	2	24	203
GO:0032467	positive regulation of cytokinesis	1.47e-02	1.00e+00	6.083	1	1	16
GO:0017022	myosin binding	1.47e-02	1.00e+00	6.083	1	2	16
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1.56e-02	1.00e+00	5.996	1	1	17
GO:0030054	cell junction	1.61e-02	1.00e+00	3.315	2	5	218
GO:0003899	DNA-directed RNA polymerase activity	1.65e-02	1.00e+00	5.914	1	3	18
GO:0045739	positive regulation of DNA repair	1.65e-02	1.00e+00	5.914	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	1.74e-02	1.00e+00	5.836	1	1	19
GO:0001103	RNA polymerase II repressing transcription factor binding	2.10e-02	1.00e+00	5.560	1	2	23
GO:0006370	7-methylguanosine mRNA capping	2.19e-02	1.00e+00	5.499	1	5	24
GO:0070534	protein K63-linked ubiquitination	2.19e-02	1.00e+00	5.499	1	3	24
GO:0030901	midbrain development	2.28e-02	1.00e+00	5.440	1	1	25
GO:0000976	transcription regulatory region sequence-specific DNA binding	2.28e-02	1.00e+00	5.440	1	3	25
GO:0051496	positive regulation of stress fiber assembly	2.37e-02	1.00e+00	5.383	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	2.46e-02	1.00e+00	5.329	1	4	27
GO:0050885	neuromuscular process controlling balance	2.55e-02	1.00e+00	5.276	1	1	28
GO:0016881	acid-amino acid ligase activity	2.55e-02	1.00e+00	5.276	1	3	28
GO:0006418	tRNA aminoacylation for protein translation	2.64e-02	1.00e+00	5.225	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	2.64e-02	1.00e+00	5.225	1	6	29
GO:0042752	regulation of circadian rhythm	2.64e-02	1.00e+00	5.225	1	5	29
GO:0043130	ubiquitin binding	2.73e-02	1.00e+00	5.177	1	3	30
GO:0032154	cleavage furrow	2.73e-02	1.00e+00	5.177	1	3	30
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	2.82e-02	1.00e+00	5.129	1	1	31
GO:0021762	substantia nigra development	3.09e-02	1.00e+00	4.996	1	1	34
GO:0044822	poly(A) RNA binding	3.15e-02	1.00e+00	2.026	3	45	799
GO:0050434	positive regulation of viral transcription	3.18e-02	1.00e+00	4.954	1	5	35
GO:0007266	Rho protein signal transduction	3.18e-02	1.00e+00	4.954	1	2	35
GO:0030900	forebrain development	3.27e-02	1.00e+00	4.914	1	2	36
GO:0030334	regulation of cell migration	3.27e-02	1.00e+00	4.914	1	2	36
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	198	4124
GO:0048511	rhythmic process	3.45e-02	1.00e+00	4.836	1	5	38
GO:0006396	RNA processing	3.63e-02	1.00e+00	4.762	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0006366	transcription from RNA polymerase II promoter	3.72e-02	1.00e+00	2.670	2	23	341
GO:0004867	serine-type endopeptidase inhibitor activity	3.81e-02	1.00e+00	4.691	1	1	42
GO:0001047	core promoter binding	3.81e-02	1.00e+00	4.691	1	4	42
GO:0000724	double-strand break repair via homologous recombination	3.81e-02	1.00e+00	4.691	1	5	42
GO:0005634	nucleus	4.18e-02	1.00e+00	1.004	6	158	3246
GO:0005524	ATP binding	4.20e-02	1.00e+00	1.868	3	37	892
GO:0008203	cholesterol metabolic process	4.25e-02	1.00e+00	4.529	1	2	47
GO:0007626	locomotory behavior	4.25e-02	1.00e+00	4.529	1	1	47
GO:0032481	positive regulation of type I interferon production	4.34e-02	1.00e+00	4.499	1	3	48
GO:0000151	ubiquitin ligase complex	4.34e-02	1.00e+00	4.499	1	4	48
GO:0006310	DNA recombination	4.52e-02	1.00e+00	4.440	1	8	50
GO:0034146	toll-like receptor 5 signaling pathway	4.52e-02	1.00e+00	4.440	1	3	50
GO:0034166	toll-like receptor 10 signaling pathway	4.52e-02	1.00e+00	4.440	1	3	50
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	6	53
GO:0045666	positive regulation of neuron differentiation	4.78e-02	1.00e+00	4.356	1	3	53
GO:0003677	DNA binding	4.89e-02	1.00e+00	1.781	3	52	947
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	4.96e-02	1.00e+00	4.302	1	3	55
GO:0034162	toll-like receptor 9 signaling pathway	4.96e-02	1.00e+00	4.302	1	3	55
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	4.96e-02	1.00e+00	4.302	1	3	55
GO:0034134	toll-like receptor 2 signaling pathway	5.05e-02	1.00e+00	4.276	1	3	56
GO:0042826	histone deacetylase binding	5.22e-02	1.00e+00	4.225	1	5	58
GO:0000785	chromatin	5.31e-02	1.00e+00	4.201	1	6	59
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	5	61
GO:0006464	cellular protein modification process	5.49e-02	1.00e+00	4.153	1	4	61
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	5.49e-02	1.00e+00	4.153	1	4	61
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	6.01e-02	1.00e+00	4.017	1	5	67
GO:0050852	T cell receptor signaling pathway	6.10e-02	1.00e+00	3.996	1	2	68
GO:0045087	innate immune response	6.20e-02	1.00e+00	2.263	2	12	452
GO:0010951	negative regulation of endopeptidase activity	6.36e-02	1.00e+00	3.934	1	2	71
GO:0005829	cytosol	6.48e-02	1.00e+00	1.280	4	88	1787
GO:0030496	midbody	6.53e-02	1.00e+00	3.894	1	6	73
GO:0016363	nuclear matrix	6.53e-02	1.00e+00	3.894	1	10	73
GO:0034142	toll-like receptor 4 signaling pathway	6.53e-02	1.00e+00	3.894	1	3	73
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	5	74
GO:0051056	regulation of small GTPase mediated signal transduction	6.79e-02	1.00e+00	3.836	1	2	76
GO:0005938	cell cortex	6.88e-02	1.00e+00	3.817	1	6	77
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	7.40e-02	1.00e+00	3.708	1	2	83
GO:0002224	toll-like receptor signaling pathway	7.40e-02	1.00e+00	3.708	1	3	83
GO:0030027	lamellipodium	7.83e-02	1.00e+00	3.624	1	3	88
GO:0051092	positive regulation of NF-kappaB transcription factor activity	7.91e-02	1.00e+00	3.608	1	2	89
GO:0030036	actin cytoskeleton organization	8.00e-02	1.00e+00	3.592	1	4	90
GO:0008201	heparin binding	8.08e-02	1.00e+00	3.576	1	4	91
GO:0006511	ubiquitin-dependent protein catabolic process	8.17e-02	1.00e+00	3.560	1	6	92
GO:0007179	transforming growth factor beta receptor signaling pathway	9.44e-02	1.00e+00	3.342	1	5	107
GO:0006397	mRNA processing	9.70e-02	1.00e+00	3.302	1	12	110
GO:0003924	GTPase activity	1.05e-01	1.00e+00	3.189	1	7	119
GO:0006184	GTP catabolic process	1.14e-01	1.00e+00	3.061	1	7	130
GO:0038095	Fc-epsilon receptor signaling pathway	1.15e-01	1.00e+00	3.039	1	2	132
GO:0030168	platelet activation	1.23e-01	1.00e+00	2.944	1	5	141
GO:0044212	transcription regulatory region DNA binding	1.24e-01	1.00e+00	2.924	1	13	143
GO:0019221	cytokine-mediated signaling pathway	1.48e-01	1.00e+00	2.657	1	10	172
GO:0007264	small GTPase mediated signal transduction	1.49e-01	1.00e+00	2.641	1	8	174
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	13	176
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	17	179
GO:0003713	transcription coactivator activity	1.57e-01	1.00e+00	2.560	1	21	184
GO:0016567	protein ubiquitination	1.61e-01	1.00e+00	2.529	1	14	188
GO:0005856	cytoskeleton	1.62e-01	1.00e+00	2.514	1	8	190
GO:0005525	GTP binding	1.68e-01	1.00e+00	2.461	1	12	197
GO:0048011	neurotrophin TRK receptor signaling pathway	1.69e-01	1.00e+00	2.447	1	8	199
GO:0008134	transcription factor binding	1.77e-01	1.00e+00	2.376	1	10	209
GO:0043234	protein complex	1.78e-01	1.00e+00	2.369	1	13	210
GO:0070062	extracellular vesicular exosome	1.81e-01	1.00e+00	0.988	3	51	1641
GO:0030198	extracellular matrix organization	1.86e-01	1.00e+00	2.296	1	7	221
GO:0007186	G-protein coupled receptor signaling pathway	1.92e-01	1.00e+00	2.244	1	4	229
GO:0007411	axon guidance	1.98e-01	1.00e+00	2.195	1	8	237
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	22	247
GO:0046982	protein heterodimerization activity	2.19e-01	1.00e+00	2.034	1	11	265
GO:0006508	proteolysis	2.19e-01	1.00e+00	2.039	1	11	264
GO:0005925	focal adhesion	2.32e-01	1.00e+00	1.944	1	14	282
GO:0009986	cell surface	2.38e-01	1.00e+00	1.899	1	5	291
GO:0045892	negative regulation of transcription, DNA-templated	2.57e-01	1.00e+00	1.775	1	17	317
GO:0007596	blood coagulation	2.72e-01	1.00e+00	1.678	1	13	339
GO:0042802	identical protein binding	2.83e-01	1.00e+00	1.616	1	15	354
GO:0016020	membrane	3.08e-01	1.00e+00	0.846	2	56	1207
GO:0042803	protein homodimerization activity	3.32e-01	1.00e+00	1.342	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.50e-01	1.00e+00	1.251	1	29	456
GO:0005737	cytoplasm	4.54e-01	1.00e+00	0.306	3	127	2633
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.59e-01	1.00e+00	0.753	1	29	644
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	32	659
GO:0005886	plasma membrane	5.10e-01	1.00e+00	0.283	2	46	1784
GO:0006351	transcription, DNA-templated	6.50e-01	1.00e+00	0.012	1	47	1076
GO:0005730	nucleolus	6.98e-01	1.00e+00	-0.166	1	74	1217
GO:0016021	integral component of membrane	7.83e-01	1.00e+00	-0.492	1	19	1526

chia-Fav

reg-snw-7334

Statistics

Genes (9)

Interactions (9)

Related GO terms (178)