reg-snw-5905

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.303	8.29e-08	2.41e-02	1.91e-02

chia-screen-data-Fav-reg-snw-5905 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
SMU1	55234	1	-2.345	2.303	34	TF	Yes	-
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
XPNPEP1	7511	8	-1.779	2.386	76	TF	-	-
SMG7	9887	1	-1.753	2.303	58	TF	-	-
[ RANGAP1 ]	5905	3	-1.596	2.303	74	-	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
FUS	2521	11	-1.980	2.414	53	TF	-	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
NOLC1	9221	15	-1.985	2.503	113	TF	-	-

Interactions (18)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
FUS	2521	RANGAP1	5905	pd	>	reg.ITFP.txt: no annot
RANGAP1	5905	NOLC1	9221	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	RANGAP1	5905	pd	>	reg.ITFP.txt: no annot
FUS	2521	POLR2E	5434	pd	<>	reg.ITFP.txt: no annot
SMG7	9887	SMU1	55234	pd	<>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
NOLC1	9221	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
RANGAP1	5905	VARS	7407	pd	<	reg.ITFP.txt: no annot
RANGAP1	5905	SMG7	9887	pd	<	reg.ITFP.txt: no annot
FUS	2521	HNRNPU	3192	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	XPNPEP1	7511	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
RANGAP1	5905	XPNPEP1	7511	pd	<	reg.ITFP.txt: no annot

Related GO terms (151)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010467	gene expression	4.32e-04	1.00e+00	2.811	5	49	535
GO:0000398	mRNA splicing, via spliceosome	5.72e-04	1.00e+00	4.138	3	15	128
GO:0008380	RNA splicing	1.20e-03	1.00e+00	3.772	3	21	165
GO:0004832	valine-tRNA ligase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0061383	trabecula morphogenesis	1.33e-03	1.00e+00	9.553	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0008175	tRNA methyltransferase activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.33e-03	1.00e+00	9.553	1	1	1
GO:0005098	Ran GTPase activator activity	1.33e-03	1.00e+00	9.553	1	1	1
GO:0005737	cytoplasm	1.77e-03	1.00e+00	1.360	9	127	2633
GO:0033688	regulation of osteoblast proliferation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0035303	regulation of dephosphorylation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0032853	positive regulation of Ran GTPase activity	3.99e-03	1.00e+00	7.968	1	1	3
GO:0070006	metalloaminopeptidase activity	3.99e-03	1.00e+00	7.968	1	1	3
GO:0001649	osteoblast differentiation	4.19e-03	1.00e+00	4.344	2	5	74
GO:0036089	cleavage furrow formation	5.32e-03	1.00e+00	7.553	1	1	4
GO:0007000	nucleolus organization	5.32e-03	1.00e+00	7.553	1	1	4
GO:0010815	bradykinin catabolic process	5.32e-03	1.00e+00	7.553	1	1	4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.64e-03	1.00e+00	7.231	1	2	5
GO:0043931	ossification involved in bone maturation	6.64e-03	1.00e+00	7.231	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.64e-03	1.00e+00	7.231	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.64e-03	1.00e+00	7.231	1	1	5
GO:0050847	progesterone receptor signaling pathway	7.96e-03	1.00e+00	6.968	1	2	6
GO:0002181	cytoplasmic translation	7.96e-03	1.00e+00	6.968	1	1	6
GO:0001055	RNA polymerase II activity	7.96e-03	1.00e+00	6.968	1	3	6
GO:0043297	apical junction assembly	7.96e-03	1.00e+00	6.968	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	7.96e-03	1.00e+00	6.968	1	2	6
GO:0046826	negative regulation of protein export from nucleus	7.96e-03	1.00e+00	6.968	1	1	6
GO:0007049	cell cycle	9.85e-03	1.00e+00	3.707	2	8	115
GO:0090307	spindle assembly involved in mitosis	1.06e-02	1.00e+00	6.553	1	2	8
GO:0006450	regulation of translational fidelity	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010388	cullin deneddylation	1.06e-02	1.00e+00	6.553	1	4	8
GO:0043296	apical junction complex	1.06e-02	1.00e+00	6.553	1	1	8
GO:0071354	cellular response to interleukin-6	1.19e-02	1.00e+00	6.383	1	1	9
GO:0005515	protein binding	1.21e-02	1.00e+00	0.865	10	198	4124
GO:0005736	DNA-directed RNA polymerase I complex	1.32e-02	1.00e+00	6.231	1	4	10
GO:0005095	GTPase inhibitor activity	1.32e-02	1.00e+00	6.231	1	1	10
GO:0050919	negative chemotaxis	1.32e-02	1.00e+00	6.231	1	1	10
GO:0001054	RNA polymerase I activity	1.32e-02	1.00e+00	6.231	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.46e-02	1.00e+00	6.094	1	4	11
GO:0050772	positive regulation of axonogenesis	1.72e-02	1.00e+00	5.853	1	2	13
GO:0050770	regulation of axonogenesis	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.72e-02	1.00e+00	5.853	1	3	13
GO:0001056	RNA polymerase III activity	1.72e-02	1.00e+00	5.853	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.72e-02	1.00e+00	5.853	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.85e-02	1.00e+00	5.746	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.85e-02	1.00e+00	5.746	1	3	14
GO:0050771	negative regulation of axonogenesis	1.85e-02	1.00e+00	5.746	1	2	14
GO:0051721	protein phosphatase 2A binding	1.85e-02	1.00e+00	5.746	1	1	14
GO:0016575	histone deacetylation	1.85e-02	1.00e+00	5.746	1	2	14
GO:0004177	aminopeptidase activity	1.85e-02	1.00e+00	5.746	1	3	14
GO:0005829	cytosol	1.98e-02	1.00e+00	1.335	6	88	1787
GO:0000188	inactivation of MAPK activity	1.98e-02	1.00e+00	5.646	1	1	15
GO:0032467	positive regulation of cytokinesis	2.11e-02	1.00e+00	5.553	1	1	16
GO:0017022	myosin binding	2.11e-02	1.00e+00	5.553	1	2	16
GO:0003899	DNA-directed RNA polymerase activity	2.37e-02	1.00e+00	5.383	1	3	18
GO:0005654	nucleoplasm	2.38e-02	1.00e+00	1.778	4	68	876
GO:0036464	cytoplasmic ribonucleoprotein granule	2.50e-02	1.00e+00	5.305	1	1	19
GO:0071897	DNA biosynthetic process	2.63e-02	1.00e+00	5.231	1	2	20
GO:0005525	GTP binding	2.73e-02	1.00e+00	2.931	2	12	197
GO:0006370	7-methylguanosine mRNA capping	3.15e-02	1.00e+00	4.968	1	5	24
GO:0008180	COP9 signalosome	3.15e-02	1.00e+00	4.968	1	6	24
GO:0030145	manganese ion binding	3.41e-02	1.00e+00	4.853	1	3	26
GO:0051496	positive regulation of stress fiber assembly	3.41e-02	1.00e+00	4.853	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	3.54e-02	1.00e+00	4.798	1	4	27
GO:0006418	tRNA aminoacylation for protein translation	3.79e-02	1.00e+00	4.695	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	3.79e-02	1.00e+00	4.695	1	6	29
GO:0032154	cleavage furrow	3.92e-02	1.00e+00	4.646	1	3	30
GO:0045111	intermediate filament cytoskeleton	4.05e-02	1.00e+00	4.599	1	3	31
GO:0003723	RNA binding	4.14e-02	1.00e+00	2.605	2	22	247
GO:0015030	Cajal body	4.18e-02	1.00e+00	4.553	1	3	32
GO:0021762	substantia nigra development	4.44e-02	1.00e+00	4.466	1	1	34
GO:0007254	JNK cascade	4.44e-02	1.00e+00	4.466	1	1	34
GO:0050434	positive regulation of viral transcription	4.56e-02	1.00e+00	4.424	1	5	35
GO:0007266	Rho protein signal transduction	4.56e-02	1.00e+00	4.424	1	2	35
GO:0030334	regulation of cell migration	4.69e-02	1.00e+00	4.383	1	2	36
GO:0006396	RNA processing	5.20e-02	1.00e+00	4.231	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	5.20e-02	1.00e+00	4.231	1	6	40
GO:0006406	mRNA export from nucleus	5.71e-02	1.00e+00	4.094	1	7	44
GO:0032481	positive regulation of type I interferon production	6.21e-02	1.00e+00	3.968	1	3	48
GO:0005643	nuclear pore	6.58e-02	1.00e+00	3.881	1	12	51
GO:0006368	transcription elongation from RNA polymerase II promoter	6.71e-02	1.00e+00	3.853	1	8	52
GO:0006289	nucleotide-excision repair	6.83e-02	1.00e+00	3.825	1	6	53
GO:0045666	positive regulation of neuron differentiation	6.83e-02	1.00e+00	3.825	1	3	53
GO:0000776	kinetochore	7.08e-02	1.00e+00	3.772	1	8	55
GO:0000777	condensed chromosome kinetochore	7.33e-02	1.00e+00	3.720	1	6	57
GO:0042826	histone deacetylase binding	7.46e-02	1.00e+00	3.695	1	5	58
GO:0071013	catalytic step 2 spliceosome	7.83e-02	1.00e+00	3.622	1	5	61
GO:0044822	poly(A) RNA binding	8.42e-02	1.00e+00	1.496	3	45	799
GO:0006364	rRNA processing	8.57e-02	1.00e+00	3.487	1	2	67
GO:0000922	spindle pole	8.69e-02	1.00e+00	3.466	1	4	68
GO:0030308	negative regulation of cell growth	8.93e-02	1.00e+00	3.424	1	3	70
GO:0030496	midbody	9.30e-02	1.00e+00	3.363	1	6	73
GO:0051056	regulation of small GTPase mediated signal transduction	9.66e-02	1.00e+00	3.305	1	2	76
GO:0005938	cell cortex	9.79e-02	1.00e+00	3.286	1	6	77
GO:0005634	nucleus	1.02e-01	1.00e+00	0.696	7	158	3246
GO:0030529	ribonucleoprotein complex	1.04e-01	1.00e+00	3.195	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	1.05e-01	1.00e+00	3.178	1	2	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.06e-01	1.00e+00	3.161	1	5	84
GO:0005524	ATP binding	1.09e-01	1.00e+00	1.337	3	37	892
GO:0016032	viral process	1.09e-01	1.00e+00	1.811	2	30	428
GO:0030027	lamellipodium	1.11e-01	1.00e+00	3.094	1	3	88
GO:0030036	actin cytoskeleton organization	1.13e-01	1.00e+00	3.061	1	4	90
GO:0003677	DNA binding	1.25e-01	1.00e+00	1.251	3	52	947
GO:0007179	transforming growth factor beta receptor signaling pathway	1.34e-01	1.00e+00	2.811	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.35e-01	1.00e+00	2.798	1	2	108
GO:0042981	regulation of apoptotic process	1.39e-01	1.00e+00	2.746	1	4	112
GO:0003924	GTPase activity	1.47e-01	1.00e+00	2.658	1	7	119
GO:0031965	nuclear membrane	1.60e-01	1.00e+00	2.531	1	8	130
GO:0006184	GTP catabolic process	1.60e-01	1.00e+00	2.531	1	7	130
GO:0030168	platelet activation	1.72e-01	1.00e+00	2.413	1	5	141
GO:0044212	transcription regulatory region DNA binding	1.75e-01	1.00e+00	2.393	1	13	143
GO:0006367	transcription initiation from RNA polymerase II promoter	1.94e-01	1.00e+00	2.222	1	18	161
GO:0007165	signal transduction	1.97e-01	1.00e+00	1.282	2	24	618
GO:0007067	mitotic nuclear division	1.99e-01	1.00e+00	2.187	1	9	165
GO:0016071	mRNA metabolic process	2.04e-01	1.00e+00	2.144	1	10	170
GO:0007264	small GTPase mediated signal transduction	2.09e-01	1.00e+00	2.110	1	8	174
GO:0000166	nucleotide binding	2.11e-01	1.00e+00	2.094	1	13	176
GO:0005739	mitochondrion	2.17e-01	1.00e+00	1.189	2	32	659
GO:0016070	RNA metabolic process	2.23e-01	1.00e+00	1.998	1	10	188
GO:0005856	cytoskeleton	2.26e-01	1.00e+00	1.983	1	8	190
GO:0005743	mitochondrial inner membrane	2.33e-01	1.00e+00	1.931	1	9	197
GO:0048011	neurotrophin TRK receptor signaling pathway	2.35e-01	1.00e+00	1.916	1	8	199
GO:0006281	DNA repair	2.39e-01	1.00e+00	1.888	1	24	203
GO:0019899	enzyme binding	2.46e-01	1.00e+00	1.839	1	7	210
GO:0030054	cell junction	2.54e-01	1.00e+00	1.785	1	5	218
GO:0007411	axon guidance	2.74e-01	1.00e+00	1.664	1	8	237
GO:0006508	proteolysis	3.00e-01	1.00e+00	1.509	1	11	264
GO:0008285	negative regulation of cell proliferation	3.12e-01	1.00e+00	1.439	1	11	277
GO:0005925	focal adhesion	3.17e-01	1.00e+00	1.413	1	14	282
GO:0009986	cell surface	3.25e-01	1.00e+00	1.368	1	5	291
GO:0000278	mitotic cell cycle	3.46e-01	1.00e+00	1.258	1	28	314
GO:0045892	negative regulation of transcription, DNA-templated	3.49e-01	1.00e+00	1.245	1	17	317
GO:0007596	blood coagulation	3.68e-01	1.00e+00	1.148	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	3.70e-01	1.00e+00	1.139	1	23	341
GO:0048471	perinuclear region of cytoplasm	3.73e-01	1.00e+00	1.127	1	11	344
GO:0070062	extracellular vesicular exosome	3.77e-01	1.00e+00	0.458	3	51	1641
GO:0042802	identical protein binding	3.81e-01	1.00e+00	1.085	1	15	354
GO:0045893	positive regulation of transcription, DNA-templated	4.01e-01	1.00e+00	0.995	1	21	377
GO:0042803	protein homodimerization activity	4.42e-01	1.00e+00	0.811	1	13	428
GO:0045087	innate immune response	4.60e-01	1.00e+00	0.733	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.63e-01	1.00e+00	0.720	1	29	456
GO:0016020	membrane	4.90e-01	1.00e+00	0.316	2	56	1207
GO:0005730	nucleolus	4.95e-01	1.00e+00	0.304	2	74	1217
GO:0005887	integral component of plasma membrane	5.46e-01	1.00e+00	0.386	1	8	575
GO:0006355	regulation of transcription, DNA-templated	6.28e-01	1.00e+00	0.071	1	31	715
GO:0008270	zinc ion binding	6.34e-01	1.00e+00	0.047	1	39	727
GO:0005886	plasma membrane	9.28e-01	1.00e+00	-1.248	1	46	1784

chia-Fav

reg-snw-5905

Statistics

Genes (13)

Interactions (18)

Related GO terms (151)