reg-snw-5434

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.644	8.58e-10	1.48e-03	1.62e-03

chia-screen-data-Fav-reg-snw-5434 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
[ POLR2E ]	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot

Related GO terms (120)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004832	valine-tRNA ligase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0061383	trabecula morphogenesis	7.17e-04	1.00e+00	10.446	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	7.17e-04	1.00e+00	10.446	1	1	1
GO:0006438	valyl-tRNA aminoacylation	7.17e-04	1.00e+00	10.446	1	1	1
GO:0008175	tRNA methyltransferase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0001649	osteoblast differentiation	1.16e-03	1.00e+00	5.237	2	5	74
GO:0033688	regulation of osteoblast proliferation	1.43e-03	1.00e+00	9.446	1	1	2
GO:0036089	cleavage furrow formation	2.86e-03	1.00e+00	8.446	1	1	4
GO:0000398	mRNA splicing, via spliceosome	3.43e-03	1.00e+00	4.446	2	15	128
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	3.58e-03	1.00e+00	8.124	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	3.58e-03	1.00e+00	8.124	1	1	5
GO:0038027	apolipoprotein A-I-mediated signaling pathway	3.58e-03	1.00e+00	8.124	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	3.58e-03	1.00e+00	8.124	1	2	5
GO:0043931	ossification involved in bone maturation	3.58e-03	1.00e+00	8.124	1	1	5
GO:0050847	progesterone receptor signaling pathway	4.29e-03	1.00e+00	7.861	1	2	6
GO:0002181	cytoplasmic translation	4.29e-03	1.00e+00	7.861	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	4.29e-03	1.00e+00	7.861	1	2	6
GO:0001055	RNA polymerase II activity	4.29e-03	1.00e+00	7.861	1	3	6
GO:0043297	apical junction assembly	4.29e-03	1.00e+00	7.861	1	1	6
GO:0010467	gene expression	4.85e-03	1.00e+00	2.968	3	49	535
GO:0008380	RNA splicing	5.64e-03	1.00e+00	4.080	2	21	165
GO:0010944	negative regulation of transcription by competitive promoter binding	5.72e-03	1.00e+00	7.446	1	1	8
GO:0010388	cullin deneddylation	5.72e-03	1.00e+00	7.446	1	4	8
GO:0090307	spindle assembly involved in mitosis	5.72e-03	1.00e+00	7.446	1	2	8
GO:0006450	regulation of translational fidelity	5.72e-03	1.00e+00	7.446	1	1	8
GO:0043296	apical junction complex	5.72e-03	1.00e+00	7.446	1	1	8
GO:0071354	cellular response to interleukin-6	6.44e-03	1.00e+00	7.276	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	7.15e-03	1.00e+00	7.124	1	4	10
GO:0001054	RNA polymerase I activity	7.15e-03	1.00e+00	7.124	1	4	10
GO:0005095	GTPase inhibitor activity	7.15e-03	1.00e+00	7.124	1	1	10
GO:0050919	negative chemotaxis	7.15e-03	1.00e+00	7.124	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	7.86e-03	1.00e+00	6.987	1	4	11
GO:0005665	DNA-directed RNA polymerase II, core complex	9.28e-03	1.00e+00	6.746	1	3	13
GO:0001056	RNA polymerase III activity	9.28e-03	1.00e+00	6.746	1	3	13
GO:0050772	positive regulation of axonogenesis	9.28e-03	1.00e+00	6.746	1	2	13
GO:0050770	regulation of axonogenesis	9.28e-03	1.00e+00	6.746	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	9.28e-03	1.00e+00	6.746	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	9.28e-03	1.00e+00	6.746	1	1	13
GO:0006385	transcription elongation from RNA polymerase III promoter	1.00e-02	1.00e+00	6.639	1	3	14
GO:0006386	termination of RNA polymerase III transcription	1.00e-02	1.00e+00	6.639	1	3	14
GO:0050771	negative regulation of axonogenesis	1.00e-02	1.00e+00	6.639	1	2	14
GO:0016575	histone deacetylation	1.00e-02	1.00e+00	6.639	1	2	14
GO:0000188	inactivation of MAPK activity	1.07e-02	1.00e+00	6.539	1	1	15
GO:0032467	positive regulation of cytokinesis	1.14e-02	1.00e+00	6.446	1	1	16
GO:0017022	myosin binding	1.14e-02	1.00e+00	6.446	1	2	16
GO:0003899	DNA-directed RNA polymerase activity	1.28e-02	1.00e+00	6.276	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	1.35e-02	1.00e+00	6.198	1	1	19
GO:0071897	DNA biosynthetic process	1.43e-02	1.00e+00	6.124	1	2	20
GO:0008180	COP9 signalosome	1.71e-02	1.00e+00	5.861	1	6	24
GO:0006370	7-methylguanosine mRNA capping	1.71e-02	1.00e+00	5.861	1	5	24
GO:0051496	positive regulation of stress fiber assembly	1.85e-02	1.00e+00	5.746	1	2	26
GO:0005654	nucleoplasm	1.91e-02	1.00e+00	2.256	3	68	876
GO:0006360	transcription from RNA polymerase I promoter	1.92e-02	1.00e+00	5.691	1	4	27
GO:0006418	tRNA aminoacylation for protein translation	2.06e-02	1.00e+00	5.588	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	2.06e-02	1.00e+00	5.588	1	6	29
GO:0032154	cleavage furrow	2.13e-02	1.00e+00	5.539	1	3	30
GO:0021762	substantia nigra development	2.41e-02	1.00e+00	5.359	1	1	34
GO:0007254	JNK cascade	2.41e-02	1.00e+00	5.359	1	1	34
GO:0007266	Rho protein signal transduction	2.48e-02	1.00e+00	5.317	1	2	35
GO:0050434	positive regulation of viral transcription	2.48e-02	1.00e+00	5.317	1	5	35
GO:0030334	regulation of cell migration	2.55e-02	1.00e+00	5.276	1	2	36
GO:0006396	RNA processing	2.83e-02	1.00e+00	5.124	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	2.83e-02	1.00e+00	5.124	1	6	40
GO:0032481	positive regulation of type I interferon production	3.39e-02	1.00e+00	4.861	1	3	48
GO:0016032	viral process	3.48e-02	1.00e+00	2.705	2	30	428
GO:0006368	transcription elongation from RNA polymerase II promoter	3.67e-02	1.00e+00	4.746	1	8	52
GO:0045666	positive regulation of neuron differentiation	3.74e-02	1.00e+00	4.718	1	3	53
GO:0006289	nucleotide-excision repair	3.74e-02	1.00e+00	4.718	1	6	53
GO:0042826	histone deacetylase binding	4.09e-02	1.00e+00	4.588	1	5	58
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0030308	negative regulation of cell growth	4.91e-02	1.00e+00	4.317	1	3	70
GO:0030496	midbody	5.12e-02	1.00e+00	4.256	1	6	73
GO:0051056	regulation of small GTPase mediated signal transduction	5.32e-02	1.00e+00	4.198	1	2	76
GO:0005938	cell cortex	5.39e-02	1.00e+00	4.179	1	6	77
GO:0030529	ribonucleoprotein complex	5.73e-02	1.00e+00	4.088	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	5.80e-02	1.00e+00	4.071	1	2	83
GO:0030027	lamellipodium	6.14e-02	1.00e+00	3.987	1	3	88
GO:0030036	actin cytoskeleton organization	6.28e-02	1.00e+00	3.954	1	4	90
GO:0007179	transforming growth factor beta receptor signaling pathway	7.42e-02	1.00e+00	3.705	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	7.49e-02	1.00e+00	3.691	1	2	108
GO:0005739	mitochondrion	7.61e-02	1.00e+00	2.082	2	32	659
GO:0042981	regulation of apoptotic process	7.76e-02	1.00e+00	3.639	1	4	112
GO:0007049	cell cycle	7.96e-02	1.00e+00	3.601	1	8	115
GO:0003924	GTPase activity	8.23e-02	1.00e+00	3.551	1	7	119
GO:0006184	GTP catabolic process	8.96e-02	1.00e+00	3.424	1	7	130
GO:0030168	platelet activation	9.68e-02	1.00e+00	3.306	1	5	141
GO:0044212	transcription regulatory region DNA binding	9.81e-02	1.00e+00	3.286	1	13	143
GO:0006367	transcription initiation from RNA polymerase II promoter	1.10e-01	1.00e+00	3.115	1	18	161
GO:0007264	small GTPase mediated signal transduction	1.18e-01	1.00e+00	3.003	1	8	174
GO:0005515	protein binding	1.19e-01	1.00e+00	0.758	5	198	4124
GO:0005829	cytosol	1.20e-01	1.00e+00	1.228	3	88	1787
GO:0005524	ATP binding	1.29e-01	1.00e+00	1.645	2	37	892
GO:0005856	cytoskeleton	1.29e-01	1.00e+00	2.876	1	8	190
GO:0005743	mitochondrial inner membrane	1.33e-01	1.00e+00	2.824	1	9	197
GO:0005525	GTP binding	1.33e-01	1.00e+00	2.824	1	12	197
GO:0048011	neurotrophin TRK receptor signaling pathway	1.34e-01	1.00e+00	2.809	1	8	199
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	24	203
GO:0019899	enzyme binding	1.41e-01	1.00e+00	2.732	1	7	210
GO:0003677	DNA binding	1.42e-01	1.00e+00	1.559	2	52	947
GO:0030054	cell junction	1.46e-01	1.00e+00	2.678	1	5	218
GO:0007411	axon guidance	1.58e-01	1.00e+00	2.557	1	8	237
GO:0003723	RNA binding	1.64e-01	1.00e+00	2.498	1	22	247
GO:0005634	nucleus	1.72e-01	1.00e+00	0.782	4	158	3246
GO:0008285	negative regulation of cell proliferation	1.82e-01	1.00e+00	2.332	1	11	277
GO:0005925	focal adhesion	1.86e-01	1.00e+00	2.306	1	14	282
GO:0009986	cell surface	1.91e-01	1.00e+00	2.261	1	5	291
GO:0045892	negative regulation of transcription, DNA-templated	2.06e-01	1.00e+00	2.138	1	17	317
GO:0016020	membrane	2.11e-01	1.00e+00	1.209	2	56	1207
GO:0007596	blood coagulation	2.19e-01	1.00e+00	2.041	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	2.20e-01	1.00e+00	2.032	1	23	341
GO:0045893	positive regulation of transcription, DNA-templated	2.41e-01	1.00e+00	1.888	1	21	377
GO:0045087	innate immune response	2.82e-01	1.00e+00	1.626	1	12	452
GO:0005737	cytoplasm	2.85e-01	1.00e+00	0.669	3	127	2633
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.85e-01	1.00e+00	1.613	1	29	456
GO:0070062	extracellular vesicular exosome	3.34e-01	1.00e+00	0.766	2	51	1641
GO:0005887	integral component of plasma membrane	3.46e-01	1.00e+00	1.279	1	8	575
GO:0007165	signal transduction	3.67e-01	1.00e+00	1.175	1	24	618
GO:0006355	regulation of transcription, DNA-templated	4.13e-01	1.00e+00	0.964	1	31	715
GO:0044822	poly(A) RNA binding	4.50e-01	1.00e+00	0.804	1	45	799
GO:0005886	plasma membrane	7.57e-01	1.00e+00	-0.355	1	46	1784

chia-Fav

reg-snw-5434

Statistics

Genes (7)

Interactions (7)

Related GO terms (120)