reg-snw-4221

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.240 1.80e-07 3.66e-02 2.81e-02
chia-screen-data-Fav-reg-snw-4221 subnetwork

Genes (13)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
RNF40 9810 10-2.0822.49238TFYes-
DNAJC10 54431 1-2.2022.24011-Yes-
CAPRIN1 4076 2-1.9342.24042---
POLR2E 5434 30-2.0372.644201TFYes-
KLC3 147700 7-2.1302.290132TFYes-
SMARCA4 6597 2-1.3812.251114TF--
NFRKB 4798 3-3.1292.25110-YesYes
HNRNPU 3192 39-2.8692.64433-Yes-
C16orf13 84326 12-2.0902.49236-Yes-
[ MEN1 ] 4221 1-1.2262.24013---
GPS1 2873 86-3.6212.68936TFYesYes
DRG2 1819 15-2.5262.49211-Yes-
SYMPK 8189 11-1.8902.49251TF--

Interactions (15)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
DRG2 1819 SYMPK 8189 pd < reg.ITFP.txt: no annot
SMARCA4 6597 DNAJC10 54431 pd > reg.ITFP.txt: no annot
SYMPK 8189 C16orf13 84326 pd > reg.ITFP.txt: no annot
NFRKB 4798 SMARCA4 6597 pd < reg.ITFP.txt: no annot
CAPRIN1 4076 SMARCA4 6597 pd < reg.ITFP.txt: no annot
MEN1 4221 SMARCA4 6597 pd < reg.ITFP.txt: no annot
SMARCA4 6597 SYMPK 8189 pd <> reg.ITFP.txt: no annot
RNF40 9810 KLC3 147700 pd <> reg.ITFP.txt: no annot
MEN1 4221 SYMPK 8189 pd < reg.ITFP.txt: no annot
HNRNPU 3192 POLR2E 5434 pd < reg.ITFP.txt: no annot
POLR2E 5434 SMARCA4 6597 pd <> reg.ITFP.txt: no annot
GPS1 2873 C16orf13 84326 pd > reg.ITFP.txt: no annot
MEN1 4221 RNF40 9810 pd < reg.ITFP.txt: no annot
SYMPK 8189 RNF40 9810 pd <> reg.ITFP.txt: no annot
DRG2 1819 SMARCA4 6597 pd < reg.ITFP.txt: no annot

Related GO terms (218)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0001933negative regulation of protein phosphorylation6.97e-041.00e+005.6462330
GO:0015036disulfide oxidoreductase activity1.33e-031.00e+009.553111
GO:0001776leukocyte homeostasis1.33e-031.00e+009.553111
GO:0034975protein folding in endoplasmic reticulum1.33e-031.00e+009.553111
GO:0006281DNA repair2.17e-031.00e+003.473324203
GO:0006338chromatin remodeling2.33e-031.00e+004.7722755
GO:0001832blastocyst growth2.66e-031.00e+008.553112
GO:0007403glial cell fate determination2.66e-031.00e+008.553112
GO:0034663endoplasmic reticulum chaperone complex2.66e-031.00e+008.553112
GO:0035887aortic smooth muscle cell differentiation2.66e-031.00e+008.553122
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor2.66e-031.00e+008.553112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis2.66e-031.00e+008.553112
GO:0016020membrane2.79e-031.00e+001.9016561207
GO:0047485protein N-terminus binding3.25e-031.00e+004.5312665
GO:0031062positive regulation of histone methylation3.99e-031.00e+007.968113
GO:0001835blastocyst hatching3.99e-031.00e+007.968113
GO:0010424DNA methylation on cytosine within a CG sequence3.99e-031.00e+007.968113
GO:0005726perichromatin fibrils3.99e-031.00e+007.968113
GO:0003407neural retina development5.32e-031.00e+007.553124
GO:0048562embryonic organ morphogenesis5.32e-031.00e+007.553114
GO:0060318definitive erythrocyte differentiation5.32e-031.00e+007.553114
GO:0032925regulation of activin receptor signaling pathway5.32e-031.00e+007.553114
GO:0033503HULC complex5.32e-031.00e+007.553114
GO:0002051osteoblast fate commitment5.32e-031.00e+007.553114
GO:0051974negative regulation of telomerase activity6.64e-031.00e+007.231115
GO:0070307lens fiber cell development6.64e-031.00e+007.231115
GO:0070934CRD-mediated mRNA stabilization6.64e-031.00e+007.231125
GO:0030957Tat protein binding6.64e-031.00e+007.231115
GO:0000403Y-form DNA binding6.64e-031.00e+007.231115
GO:0048730epidermis morphogenesis6.64e-031.00e+007.231115
GO:0061003positive regulation of dendritic spine morphogenesis6.64e-031.00e+007.231115
GO:0001055RNA polymerase II activity7.96e-031.00e+006.968136
GO:0006346methylation-dependent chromatin silencing7.96e-031.00e+006.968116
GO:0070937CRD-mediated mRNA stability complex7.96e-031.00e+006.968126
GO:0001671ATPase activator activity7.96e-031.00e+006.968116
GO:0000400four-way junction DNA binding9.28e-031.00e+006.746137
GO:0033523histone H2B ubiquitination9.28e-031.00e+006.746117
GO:0043005neuron projection9.53e-031.00e+003.73326113
GO:0051787misfolded protein binding1.06e-021.00e+006.553128
GO:0031011Ino80 complex1.06e-021.00e+006.553138
GO:0008088axon cargo transport1.06e-021.00e+006.553118
GO:0010388cullin deneddylation1.06e-021.00e+006.553148
GO:0070182DNA polymerase binding1.06e-021.00e+006.553118
GO:0010390histone monoubiquitination1.06e-021.00e+006.553128
GO:0046621negative regulation of organ growth1.19e-021.00e+006.383119
GO:0034968histone lysine methylation1.19e-021.00e+006.383119
GO:0035253ciliary rootlet1.19e-021.00e+006.383119
GO:0000398mRNA splicing, via spliceosome1.21e-021.00e+003.553215128
GO:0043923positive regulation by host of viral transcription1.32e-021.00e+006.2311110
GO:0005736DNA-directed RNA polymerase I complex1.32e-021.00e+006.2311410
GO:0005095GTPase inhibitor activity1.32e-021.00e+006.2311110
GO:0071564npBAF complex1.32e-021.00e+006.2311310
GO:0035097histone methyltransferase complex1.32e-021.00e+006.2311110
GO:0001054RNA polymerase I activity1.32e-021.00e+006.2311410
GO:0035307positive regulation of protein dephosphorylation1.32e-021.00e+006.2311110
GO:0060766negative regulation of androgen receptor signaling pathway1.46e-021.00e+006.0941411
GO:0071565nBAF complex1.46e-021.00e+006.0941311
GO:0050775positive regulation of dendrite morphogenesis1.46e-021.00e+006.0941111
GO:0030544Hsp70 protein binding1.59e-021.00e+005.9681112
GO:0070577lysine-acetylated histone binding1.59e-021.00e+005.9681212
GO:0017075syntaxin-1 binding1.72e-021.00e+005.8531113
GO:0006337nucleosome disassembly1.72e-021.00e+005.8531213
GO:0016514SWI/SNF complex1.72e-021.00e+005.8531313
GO:0005666DNA-directed RNA polymerase III complex1.72e-021.00e+005.8531313
GO:0005665DNA-directed RNA polymerase II, core complex1.72e-021.00e+005.8531313
GO:0001056RNA polymerase III activity1.72e-021.00e+005.8531313
GO:0015035protein disulfide oxidoreductase activity1.72e-021.00e+005.8531113
GO:0060347heart trabecula formation1.72e-021.00e+005.8531113
GO:0006386termination of RNA polymerase III transcription1.85e-021.00e+005.7461314
GO:0060135maternal process involved in female pregnancy1.85e-021.00e+005.7461314
GO:0030902hindbrain development1.85e-021.00e+005.7461214
GO:0006385transcription elongation from RNA polymerase III promoter1.85e-021.00e+005.7461314
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activity1.85e-021.00e+005.7461314
GO:0031514motile cilium1.85e-021.00e+005.7461114
GO:0006367transcription initiation from RNA polymerase II promoter1.87e-021.00e+003.222218161
GO:0008380RNA splicing1.96e-021.00e+003.187221165
GO:2000134negative regulation of G1/S transition of mitotic cell cycle1.98e-021.00e+005.6461215
GO:0032781positive regulation of ATPase activity1.98e-021.00e+005.6461215
GO:0002076osteoblast development1.98e-021.00e+005.6461115
GO:0000188inactivation of MAPK activity1.98e-021.00e+005.6461115
GO:0018024histone-lysine N-methyltransferase activity1.98e-021.00e+005.6461115
GO:0005719nuclear euchromatin2.11e-021.00e+005.5531216
GO:0000792heterochromatin2.24e-021.00e+005.4661117
GO:0003899DNA-directed RNA polymerase activity2.37e-021.00e+005.3831318
GO:0070412R-SMAD binding2.37e-021.00e+005.3831118
GO:0006378mRNA polyadenylation2.37e-021.00e+005.3831318
GO:0035116embryonic hindlimb morphogenesis2.37e-021.00e+005.3831218
GO:0005654nucleoplasm2.38e-021.00e+001.778468876
GO:0046329negative regulation of JNK cascade2.50e-021.00e+005.3051119
GO:0001105RNA polymerase II transcription coactivator activity2.50e-021.00e+005.3051219
GO:0036464cytoplasmic ribonucleoprotein granule2.50e-021.00e+005.3051119
GO:0043044ATP-dependent chromatin remodeling2.63e-021.00e+005.2311320
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathway2.63e-021.00e+005.2311120
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress2.63e-021.00e+005.2311120
GO:0043388positive regulation of DNA binding2.76e-021.00e+005.1611221
GO:0019894kinesin binding2.76e-021.00e+005.1611121
GO:0051781positive regulation of cell division2.89e-021.00e+005.0941222
GO:0045668negative regulation of osteoblast differentiation2.89e-021.00e+005.0941122
GO:0030433ER-associated ubiquitin-dependent protein catabolic process2.89e-021.00e+005.0941122
GO:0030177positive regulation of Wnt signaling pathway3.02e-021.00e+005.0291123
GO:0043234protein complex3.07e-021.00e+002.839213210
GO:0010467gene expression3.10e-021.00e+002.075349535
GO:00063707-methylguanosine mRNA capping3.15e-021.00e+004.9681524
GO:0008180COP9 signalosome3.15e-021.00e+004.9681624
GO:0051117ATPase binding3.15e-021.00e+004.9681124
GO:0031492nucleosomal DNA binding3.28e-021.00e+004.9091325
GO:0005634nucleus3.40e-021.00e+000.88981583246
GO:0010332response to gamma radiation3.41e-021.00e+004.8531226
GO:0010494cytoplasmic stress granule3.41e-021.00e+004.8531426
GO:0006360transcription from RNA polymerase I promoter3.54e-021.00e+004.7981427
GO:0043966histone H3 acetylation3.67e-021.00e+004.7461428
GO:0048704embryonic skeletal system morphogenesis3.67e-021.00e+004.7461128
GO:0008094DNA-dependent ATPase activity3.79e-021.00e+004.6951629
GO:0006383transcription from RNA polymerase III promoter3.79e-021.00e+004.6951629
GO:0045786negative regulation of cell cycle3.92e-021.00e+004.6461330
GO:0050681androgen receptor binding3.92e-021.00e+004.6461230
GO:0032154cleavage furrow3.92e-021.00e+004.6461330
GO:0034976response to endoplasmic reticulum stress4.05e-021.00e+004.5991231
GO:0045454cell redox homeostasis4.05e-021.00e+004.5991331
GO:0005871kinesin complex4.05e-021.00e+004.5991331
GO:0003723RNA binding4.14e-021.00e+002.605222247
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process4.18e-021.00e+004.5531132
GO:0017148negative regulation of translation4.31e-021.00e+004.5091533
GO:0032092positive regulation of protein binding4.44e-021.00e+004.4661234
GO:0007254JNK cascade4.44e-021.00e+004.4661134
GO:0000902cell morphogenesis4.56e-021.00e+004.4241535
GO:0050434positive regulation of viral transcription4.56e-021.00e+004.4241535
GO:0005515protein binding4.61e-021.00e+000.71391984124
GO:0030900forebrain development4.69e-021.00e+004.3831236
GO:0009411response to UV4.69e-021.00e+004.3831336
GO:0030674protein binding, bridging4.82e-021.00e+004.3441137
GO:0030216keratinocyte differentiation4.95e-021.00e+004.3051138
GO:0019827stem cell maintenance5.07e-021.00e+004.2681439
GO:0003777microtubule motor activity5.07e-021.00e+004.2681339
GO:0006396RNA processing5.20e-021.00e+004.2311440
GO:0006283transcription-coupled nucleotide-excision repair5.20e-021.00e+004.2311640
GO:0045669positive regulation of osteoblast differentiation5.33e-021.00e+004.1951241
GO:0004386helicase activity5.45e-021.00e+004.1611342
GO:0000932cytoplasmic mRNA processing body5.58e-021.00e+004.1271343
GO:0051087chaperone binding5.83e-021.00e+004.0611345
GO:0001570vasculogenesis5.83e-021.00e+004.0611245
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity5.83e-021.00e+004.0611245
GO:0002039p53 binding5.83e-021.00e+004.0611445
GO:0060021palate development6.08e-021.00e+003.9981147
GO:0032481positive regulation of type I interferon production6.21e-021.00e+003.9681348
GO:0000151ubiquitin ligase complex6.21e-021.00e+003.9681448
GO:0030097hemopoiesis6.21e-021.00e+003.9681348
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.33e-021.00e+003.9381449
GO:0006310DNA recombination6.46e-021.00e+003.9091850
GO:0002020protease binding6.46e-021.00e+003.9091350
GO:0045892negative regulation of transcription, DNA-templated6.47e-021.00e+002.245217317
GO:0006368transcription elongation from RNA polymerase II promoter6.71e-021.00e+003.8531852
GO:0005730nucleolus6.82e-021.00e+001.3044741217
GO:0006289nucleotide-excision repair6.83e-021.00e+003.8251653
GO:0006366transcription from RNA polymerase II promoter7.36e-021.00e+002.139223341
GO:0000165MAPK cascade7.46e-021.00e+003.6951358
GO:0000785chromatin7.58e-021.00e+003.6701659
GO:0071013catalytic step 2 spliceosome7.83e-021.00e+003.6221561
GO:0005923tight junction8.20e-021.00e+003.5531264
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity8.57e-021.00e+003.4871567
GO:0030308negative regulation of cell growth8.93e-021.00e+003.4241370
GO:0001889liver development9.06e-021.00e+003.4031471
GO:0016363nuclear matrix9.30e-021.00e+003.36311073
GO:0001649osteoblast differentiation9.42e-021.00e+003.3441574
GO:0030529ribonucleoprotein complex1.04e-011.00e+003.1951582
GO:0003690double-stranded DNA binding1.05e-011.00e+003.1781683
GO:0005737cytoplasm1.09e-011.00e+000.77561272633
GO:0006511ubiquitin-dependent protein catabolic process1.16e-011.00e+003.0291692
GO:0007050cell cycle arrest1.16e-011.00e+003.0291492
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.21e-011.00e+001.720229456
GO:0008017microtubule binding1.22e-011.00e+002.9531997
GO:0003677DNA binding1.25e-011.00e+001.251352947
GO:0005788endoplasmic reticulum lumen1.30e-011.00e+002.85314104
GO:0007179transforming growth factor beta receptor signaling pathway1.34e-011.00e+002.81115107
GO:0000790nuclear chromatin1.36e-011.00e+002.78519109
GO:0007049cell cycle1.43e-011.00e+002.70718115
GO:0007420brain development1.47e-011.00e+002.65813119
GO:0006974cellular response to DNA damage stimulus1.50e-011.00e+002.634111121
GO:0032403protein complex binding1.60e-011.00e+002.53115130
GO:0003714transcription corepressor activity1.68e-011.00e+002.45515137
GO:0031625ubiquitin protein ligase binding1.69e-011.00e+002.44417138
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.73e-011.00e+002.40317142
GO:0044212transcription regulatory region DNA binding1.75e-011.00e+002.393113143
GO:0016874ligase activity1.78e-011.00e+002.363111146
GO:0005874microtubule1.97e-011.00e+002.204110163
GO:0030425dendrite2.00e-011.00e+002.17812166
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.10e-011.00e+001.222229644
GO:0004842ubiquitin-protein transferase activity2.14e-011.00e+002.069117179
GO:0008152metabolic process2.17e-011.00e+002.04516182
GO:0003713transcription coactivator activity2.19e-011.00e+002.029121184
GO:0006954inflammatory response2.20e-011.00e+002.02213185
GO:0005856cytoskeleton2.26e-011.00e+001.98318190
GO:0005525GTP binding2.33e-011.00e+001.931112197
GO:0006357regulation of transcription from RNA polymerase II promoter2.39e-011.00e+001.888114203
GO:0006200ATP catabolic process2.56e-011.00e+001.778113219
GO:0030198extracellular matrix organization2.58e-011.00e+001.76517221
GO:0007155cell adhesion2.80e-011.00e+001.62218244
GO:0003682chromatin binding2.88e-011.00e+001.576115252
GO:0044822poly(A) RNA binding2.88e-011.00e+000.911245799
GO:0043565sequence-specific DNA binding3.10e-011.00e+001.45018275
GO:0008285negative regulation of cell proliferation3.12e-011.00e+001.439111277
GO:0009986cell surface3.25e-011.00e+001.36815291
GO:0005524ATP binding3.36e-011.00e+000.752237892
GO:0055114oxidation-reduction process3.41e-011.00e+001.28619308
GO:0045893positive regulation of transcription, DNA-templated4.01e-011.00e+000.995121377
GO:0005783endoplasmic reticulum4.04e-011.00e+000.979112381
GO:0006351transcription, DNA-templated4.28e-011.00e+000.4822471076
GO:0005829cytosol4.35e-011.00e+000.3353881787
GO:0042803protein homodimerization activity4.42e-011.00e+000.811113428
GO:0016032viral process4.42e-011.00e+000.811130428
GO:0045087innate immune response4.60e-011.00e+000.733112452
GO:0005887integral component of plasma membrane5.46e-011.00e+000.38618575
GO:0007165signal transduction5.73e-011.00e+000.282124618
GO:0005615extracellular space5.92e-011.00e+000.206115651
GO:0005739mitochondrion5.97e-011.00e+000.189132659
GO:0006355regulation of transcription, DNA-templated6.28e-011.00e+000.071131715
GO:0008270zinc ion binding6.34e-011.00e+000.047139727
GO:0005886plasma membrane9.28e-011.00e+00-1.2481461784