reg-snw-2733

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.414	2.05e-08	1.08e-02	9.33e-03

chia-screen-data-Fav-reg-snw-2733 subnetwork

Genes (11)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
LCE1E	353135	7	-2.428	2.414	31	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
FUS	2521	11	-1.980	2.414	53	TF	-	-
[ GLE1 ]	2733	1	-1.704	2.414	37	-	-	-
TAF6L	10629	1	-1.931	2.414	16	TF	-	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
FUS	2521	HNRNPU	3192	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
FUS	2521	GLE1	2733	pd	>	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
FUS	2521	POLR2E	5434	pd	<>	reg.ITFP.txt: no annot
TAF6L	10629	LCE1E	353135	pd	>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
GLE1	2733	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GLE1	2733	TAF6L	10629	pd	<	reg.ITFP.txt: no annot

Related GO terms (141)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000398	mRNA splicing, via spliceosome	3.36e-04	1.00e+00	4.379	3	15	128
GO:0008380	RNA splicing	7.07e-04	1.00e+00	4.013	3	21	165
GO:0004832	valine-tRNA ligase activity	1.13e-03	1.00e+00	9.794	1	1	1
GO:0061383	trabecula morphogenesis	1.13e-03	1.00e+00	9.794	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.13e-03	1.00e+00	9.794	1	1	1
GO:0008175	tRNA methyltransferase activity	1.13e-03	1.00e+00	9.794	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.13e-03	1.00e+00	9.794	1	1	1
GO:0010467	gene expression	2.16e-03	1.00e+00	2.731	4	49	535
GO:0033688	regulation of osteoblast proliferation	2.25e-03	1.00e+00	8.794	1	1	2
GO:0001649	osteoblast differentiation	2.98e-03	1.00e+00	4.585	2	5	74
GO:0036089	cleavage furrow formation	4.50e-03	1.00e+00	7.794	1	1	4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	5.62e-03	1.00e+00	7.472	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	5.62e-03	1.00e+00	7.472	1	2	5
GO:0043931	ossification involved in bone maturation	5.62e-03	1.00e+00	7.472	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.62e-03	1.00e+00	7.472	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	5.62e-03	1.00e+00	7.472	1	1	5
GO:0050847	progesterone receptor signaling pathway	6.74e-03	1.00e+00	7.209	1	2	6
GO:0002181	cytoplasmic translation	6.74e-03	1.00e+00	7.209	1	1	6
GO:0001055	RNA polymerase II activity	6.74e-03	1.00e+00	7.209	1	3	6
GO:0016973	poly(A)+ mRNA export from nucleus	6.74e-03	1.00e+00	7.209	1	1	6
GO:0043297	apical junction assembly	6.74e-03	1.00e+00	7.209	1	1	6
GO:0030914	STAGA complex	6.74e-03	1.00e+00	7.209	1	2	6
GO:0070937	CRD-mediated mRNA stability complex	6.74e-03	1.00e+00	7.209	1	2	6
GO:0090307	spindle assembly involved in mitosis	8.98e-03	1.00e+00	6.794	1	2	8
GO:0006450	regulation of translational fidelity	8.98e-03	1.00e+00	6.794	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	8.98e-03	1.00e+00	6.794	1	1	8
GO:0010388	cullin deneddylation	8.98e-03	1.00e+00	6.794	1	4	8
GO:0043296	apical junction complex	8.98e-03	1.00e+00	6.794	1	1	8
GO:0071354	cellular response to interleukin-6	1.01e-02	1.00e+00	6.624	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	1.12e-02	1.00e+00	6.472	1	4	10
GO:0005095	GTPase inhibitor activity	1.12e-02	1.00e+00	6.472	1	1	10
GO:0050919	negative chemotaxis	1.12e-02	1.00e+00	6.472	1	1	10
GO:0001054	RNA polymerase I activity	1.12e-02	1.00e+00	6.472	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.23e-02	1.00e+00	6.335	1	4	11
GO:0005654	nucleoplasm	1.27e-02	1.00e+00	2.019	4	68	876
GO:0050772	positive regulation of axonogenesis	1.46e-02	1.00e+00	6.094	1	2	13
GO:0050770	regulation of axonogenesis	1.46e-02	1.00e+00	6.094	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.46e-02	1.00e+00	6.094	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.46e-02	1.00e+00	6.094	1	3	13
GO:0001056	RNA polymerase III activity	1.46e-02	1.00e+00	6.094	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.46e-02	1.00e+00	6.094	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.57e-02	1.00e+00	5.987	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.57e-02	1.00e+00	5.987	1	3	14
GO:0050771	negative regulation of axonogenesis	1.57e-02	1.00e+00	5.987	1	2	14
GO:0016575	histone deacetylation	1.57e-02	1.00e+00	5.987	1	2	14
GO:0003677	DNA binding	1.66e-02	1.00e+00	1.907	4	52	947
GO:0000188	inactivation of MAPK activity	1.68e-02	1.00e+00	5.887	1	1	15
GO:0006352	DNA-templated transcription, initiation	1.68e-02	1.00e+00	5.887	1	3	15
GO:0032467	positive regulation of cytokinesis	1.79e-02	1.00e+00	5.794	1	1	16
GO:0017022	myosin binding	1.79e-02	1.00e+00	5.794	1	2	16
GO:0003899	DNA-directed RNA polymerase activity	2.01e-02	1.00e+00	5.624	1	3	18
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	2.01e-02	1.00e+00	5.624	1	2	18
GO:0036464	cytoplasmic ribonucleoprotein granule	2.12e-02	1.00e+00	5.546	1	1	19
GO:0071897	DNA biosynthetic process	2.23e-02	1.00e+00	5.472	1	2	20
GO:0031424	keratinization	2.56e-02	1.00e+00	5.270	1	2	23
GO:0000118	histone deacetylase complex	2.56e-02	1.00e+00	5.270	1	3	23
GO:0006370	7-methylguanosine mRNA capping	2.67e-02	1.00e+00	5.209	1	5	24
GO:0008180	COP9 signalosome	2.67e-02	1.00e+00	5.209	1	6	24
GO:0051496	positive regulation of stress fiber assembly	2.89e-02	1.00e+00	5.094	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	3.00e-02	1.00e+00	5.039	1	4	27
GO:0003723	RNA binding	3.02e-02	1.00e+00	2.846	2	22	247
GO:0043966	histone H3 acetylation	3.11e-02	1.00e+00	4.987	1	4	28
GO:0006418	tRNA aminoacylation for protein translation	3.22e-02	1.00e+00	4.936	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	3.22e-02	1.00e+00	4.936	1	6	29
GO:0004402	histone acetyltransferase activity	3.33e-02	1.00e+00	4.887	1	3	30
GO:0032154	cleavage furrow	3.33e-02	1.00e+00	4.887	1	3	30
GO:0021762	substantia nigra development	3.77e-02	1.00e+00	4.707	1	1	34
GO:0007254	JNK cascade	3.77e-02	1.00e+00	4.707	1	1	34
GO:0050434	positive regulation of viral transcription	3.87e-02	1.00e+00	4.665	1	5	35
GO:0007266	Rho protein signal transduction	3.87e-02	1.00e+00	4.665	1	2	35
GO:0030334	regulation of cell migration	3.98e-02	1.00e+00	4.624	1	2	36
GO:0005515	protein binding	4.12e-02	1.00e+00	0.784	8	198	4124
GO:0006396	RNA processing	4.42e-02	1.00e+00	4.472	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	4.42e-02	1.00e+00	4.472	1	6	40
GO:0006406	mRNA export from nucleus	4.85e-02	1.00e+00	4.335	1	7	44
GO:0032481	positive regulation of type I interferon production	5.28e-02	1.00e+00	4.209	1	3	48
GO:0005643	nuclear pore	5.60e-02	1.00e+00	4.122	1	12	51
GO:0006368	transcription elongation from RNA polymerase II promoter	5.71e-02	1.00e+00	4.094	1	8	52
GO:0006289	nucleotide-excision repair	5.81e-02	1.00e+00	4.066	1	6	53
GO:0042802	identical protein binding	5.81e-02	1.00e+00	2.326	2	15	354
GO:0045666	positive regulation of neuron differentiation	5.81e-02	1.00e+00	4.066	1	3	53
GO:0006338	chromatin remodeling	6.03e-02	1.00e+00	4.013	1	7	55
GO:0042826	histone deacetylase binding	6.35e-02	1.00e+00	3.936	1	5	58
GO:0071013	catalytic step 2 spliceosome	6.66e-02	1.00e+00	3.863	1	5	61
GO:0030308	negative regulation of cell growth	7.61e-02	1.00e+00	3.665	1	3	70
GO:0006325	chromatin organization	7.61e-02	1.00e+00	3.665	1	4	70
GO:0030496	midbody	7.93e-02	1.00e+00	3.604	1	6	73
GO:0016032	viral process	8.12e-02	1.00e+00	2.053	2	30	428
GO:0051056	regulation of small GTPase mediated signal transduction	8.24e-02	1.00e+00	3.546	1	2	76
GO:0005938	cell cortex	8.34e-02	1.00e+00	3.527	1	6	77
GO:0030529	ribonucleoprotein complex	8.86e-02	1.00e+00	3.436	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	8.97e-02	1.00e+00	3.419	1	2	83
GO:0030027	lamellipodium	9.48e-02	1.00e+00	3.335	1	3	88
GO:0030036	actin cytoskeleton organization	9.69e-02	1.00e+00	3.302	1	4	90
GO:0007179	transforming growth factor beta receptor signaling pathway	1.14e-01	1.00e+00	3.053	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.15e-01	1.00e+00	3.039	1	2	108
GO:0042981	regulation of apoptotic process	1.19e-01	1.00e+00	2.987	1	4	112
GO:0007049	cell cycle	1.22e-01	1.00e+00	2.948	1	8	115
GO:0003924	GTPase activity	1.26e-01	1.00e+00	2.899	1	7	119
GO:0006184	GTP catabolic process	1.37e-01	1.00e+00	2.772	1	7	130
GO:0016020	membrane	1.46e-01	1.00e+00	1.142	3	56	1207
GO:0005737	cytoplasm	1.48e-01	1.00e+00	0.753	5	127	2633
GO:0030168	platelet activation	1.48e-01	1.00e+00	2.654	1	5	141
GO:0044212	transcription regulatory region DNA binding	1.50e-01	1.00e+00	2.634	1	13	143
GO:0005739	mitochondrion	1.67e-01	1.00e+00	1.430	2	32	659
GO:0006367	transcription initiation from RNA polymerase II promoter	1.67e-01	1.00e+00	2.463	1	18	161
GO:0007264	small GTPase mediated signal transduction	1.80e-01	1.00e+00	2.351	1	8	174
GO:0000166	nucleotide binding	1.81e-01	1.00e+00	2.335	1	13	176
GO:0003713	transcription coactivator activity	1.89e-01	1.00e+00	2.270	1	21	184
GO:0005856	cytoskeleton	1.94e-01	1.00e+00	2.224	1	8	190
GO:0005743	mitochondrial inner membrane	2.01e-01	1.00e+00	2.172	1	9	197
GO:0005525	GTP binding	2.01e-01	1.00e+00	2.172	1	12	197
GO:0048011	neurotrophin TRK receptor signaling pathway	2.03e-01	1.00e+00	2.157	1	8	199
GO:0015031	protein transport	2.06e-01	1.00e+00	2.129	1	10	203
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.06e-01	1.00e+00	2.129	1	14	203
GO:0006281	DNA repair	2.06e-01	1.00e+00	2.129	1	24	203
GO:0019899	enzyme binding	2.13e-01	1.00e+00	2.080	1	7	210
GO:0030054	cell junction	2.20e-01	1.00e+00	2.026	1	5	218
GO:0044822	poly(A) RNA binding	2.26e-01	1.00e+00	1.152	2	45	799
GO:0007411	axon guidance	2.37e-01	1.00e+00	1.905	1	8	237
GO:0046982	protein heterodimerization activity	2.61e-01	1.00e+00	1.744	1	11	265
GO:0005524	ATP binding	2.66e-01	1.00e+00	0.993	2	37	892
GO:0008285	negative regulation of cell proliferation	2.71e-01	1.00e+00	1.680	1	11	277
GO:0005925	focal adhesion	2.76e-01	1.00e+00	1.654	1	14	282
GO:0070062	extracellular vesicular exosome	2.78e-01	1.00e+00	0.699	3	51	1641
GO:0009986	cell surface	2.83e-01	1.00e+00	1.609	1	5	291
GO:0005634	nucleus	2.87e-01	1.00e+00	0.451	5	158	3246
GO:0045892	negative regulation of transcription, DNA-templated	3.05e-01	1.00e+00	1.486	1	17	317
GO:0007596	blood coagulation	3.22e-01	1.00e+00	1.389	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	3.24e-01	1.00e+00	1.380	1	23	341
GO:0005829	cytosol	3.26e-01	1.00e+00	0.576	3	88	1787
GO:0045893	positive regulation of transcription, DNA-templated	3.52e-01	1.00e+00	1.236	1	21	377
GO:0045087	innate immune response	4.06e-01	1.00e+00	0.974	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.09e-01	1.00e+00	0.961	1	29	456
GO:0005887	integral component of plasma membrane	4.87e-01	1.00e+00	0.627	1	8	575
GO:0007165	signal transduction	5.13e-01	1.00e+00	0.523	1	24	618
GO:0005615	extracellular space	5.32e-01	1.00e+00	0.447	1	15	651
GO:0006355	regulation of transcription, DNA-templated	5.67e-01	1.00e+00	0.312	1	31	715
GO:0008270	zinc ion binding	5.73e-01	1.00e+00	0.288	1	39	727
GO:0005886	plasma membrane	6.24e-01	1.00e+00	-0.007	2	46	1784
GO:0005730	nucleolus	7.69e-01	1.00e+00	-0.455	1	74	1217

chia-Fav

reg-snw-2733

Statistics

Genes (11)

Interactions (13)

Related GO terms (141)