reg-snw-11333

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.430	1.64e-08	9.50e-03	8.31e-03

chia-screen-data-Fav-reg-snw-11333 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
[ PDAP1 ]	11333	1	-1.702	2.430	6	-	-	-
SNAP23	8773	4	-2.073	2.430	15	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
ARID4B	51742	3	-2.022	2.430	9	TF	Yes	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
POLR2E	5434	ARID4B	51742	pd	<>	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	SNAP23	8773	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	PDAP1	11333	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot

Related GO terms (139)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004832	valine-tRNA ligase activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0061383	trabecula morphogenesis	1.02e-03	1.00e+00	9.931	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.02e-03	1.00e+00	9.931	1	1	1
GO:0008175	tRNA methyltransferase activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.02e-03	1.00e+00	9.931	1	1	1
GO:0033688	regulation of osteoblast proliferation	2.05e-03	1.00e+00	8.931	1	1	2
GO:0001649	osteoblast differentiation	2.45e-03	1.00e+00	4.722	2	5	74
GO:0042582	azurophil granule	4.09e-03	1.00e+00	7.931	1	1	4
GO:0034773	histone H4-K20 trimethylation	4.09e-03	1.00e+00	7.931	1	1	4
GO:0036089	cleavage furrow formation	4.09e-03	1.00e+00	7.931	1	1	4
GO:0036124	histone H3-K9 trimethylation	4.09e-03	1.00e+00	7.931	1	2	4
GO:0038027	apolipoprotein A-I-mediated signaling pathway	5.11e-03	1.00e+00	7.610	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	5.11e-03	1.00e+00	7.610	1	2	5
GO:0043931	ossification involved in bone maturation	5.11e-03	1.00e+00	7.610	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.11e-03	1.00e+00	7.610	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	5.11e-03	1.00e+00	7.610	1	1	5
GO:0050847	progesterone receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	2	6
GO:0002181	cytoplasmic translation	6.13e-03	1.00e+00	7.347	1	1	6
GO:0001055	RNA polymerase II activity	6.13e-03	1.00e+00	7.347	1	3	6
GO:0043297	apical junction assembly	6.13e-03	1.00e+00	7.347	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	6.13e-03	1.00e+00	7.347	1	2	6
GO:0006903	vesicle targeting	6.13e-03	1.00e+00	7.347	1	1	6
GO:0042581	specific granule	7.15e-03	1.00e+00	7.124	1	1	7
GO:0000398	mRNA splicing, via spliceosome	7.16e-03	1.00e+00	3.931	2	15	128
GO:0090307	spindle assembly involved in mitosis	8.17e-03	1.00e+00	6.931	1	2	8
GO:0006450	regulation of translational fidelity	8.17e-03	1.00e+00	6.931	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	8.17e-03	1.00e+00	6.931	1	1	8
GO:0010388	cullin deneddylation	8.17e-03	1.00e+00	6.931	1	4	8
GO:0043296	apical junction complex	8.17e-03	1.00e+00	6.931	1	1	8
GO:0071354	cellular response to interleukin-6	9.18e-03	1.00e+00	6.762	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	1.02e-02	1.00e+00	6.610	1	4	10
GO:0005095	GTPase inhibitor activity	1.02e-02	1.00e+00	6.610	1	1	10
GO:0050919	negative chemotaxis	1.02e-02	1.00e+00	6.610	1	1	10
GO:0001054	RNA polymerase I activity	1.02e-02	1.00e+00	6.610	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.12e-02	1.00e+00	6.472	1	4	11
GO:0008380	RNA splicing	1.17e-02	1.00e+00	3.565	2	21	165
GO:0006349	regulation of gene expression by genetic imprinting	1.22e-02	1.00e+00	6.347	1	1	12
GO:0061025	membrane fusion	1.32e-02	1.00e+00	6.231	1	1	13
GO:0050772	positive regulation of axonogenesis	1.32e-02	1.00e+00	6.231	1	2	13
GO:0050770	regulation of axonogenesis	1.32e-02	1.00e+00	6.231	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.32e-02	1.00e+00	6.231	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.32e-02	1.00e+00	6.231	1	3	13
GO:0001056	RNA polymerase III activity	1.32e-02	1.00e+00	6.231	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.32e-02	1.00e+00	6.231	1	1	13
GO:0006386	termination of RNA polymerase III transcription	1.43e-02	1.00e+00	6.124	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.43e-02	1.00e+00	6.124	1	3	14
GO:0050771	negative regulation of axonogenesis	1.43e-02	1.00e+00	6.124	1	2	14
GO:0016575	histone deacetylation	1.43e-02	1.00e+00	6.124	1	2	14
GO:0010467	gene expression	1.47e-02	1.00e+00	2.453	3	49	535
GO:0000188	inactivation of MAPK activity	1.53e-02	1.00e+00	6.025	1	1	15
GO:0032467	positive regulation of cytokinesis	1.63e-02	1.00e+00	5.931	1	1	16
GO:0017022	myosin binding	1.63e-02	1.00e+00	5.931	1	2	16
GO:0003899	DNA-directed RNA polymerase activity	1.83e-02	1.00e+00	5.762	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	1.93e-02	1.00e+00	5.684	1	1	19
GO:0071897	DNA biosynthetic process	2.03e-02	1.00e+00	5.610	1	2	20
GO:0006370	7-methylguanosine mRNA capping	2.43e-02	1.00e+00	5.347	1	5	24
GO:0008180	COP9 signalosome	2.43e-02	1.00e+00	5.347	1	6	24
GO:0051496	positive regulation of stress fiber assembly	2.63e-02	1.00e+00	5.231	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	2.73e-02	1.00e+00	5.177	1	4	27
GO:0006418	tRNA aminoacylation for protein translation	2.93e-02	1.00e+00	5.073	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	2.93e-02	1.00e+00	5.073	1	6	29
GO:0032154	cleavage furrow	3.03e-02	1.00e+00	5.025	1	3	30
GO:0005925	focal adhesion	3.21e-02	1.00e+00	2.792	2	14	282
GO:0006892	post-Golgi vesicle-mediated transport	3.23e-02	1.00e+00	4.931	1	1	32
GO:0021762	substantia nigra development	3.43e-02	1.00e+00	4.844	1	1	34
GO:0007254	JNK cascade	3.43e-02	1.00e+00	4.844	1	1	34
GO:0050434	positive regulation of viral transcription	3.53e-02	1.00e+00	4.802	1	5	35
GO:0007266	Rho protein signal transduction	3.53e-02	1.00e+00	4.802	1	2	35
GO:0030334	regulation of cell migration	3.63e-02	1.00e+00	4.762	1	2	36
GO:0006396	RNA processing	4.02e-02	1.00e+00	4.610	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	4.02e-02	1.00e+00	4.610	1	6	40
GO:0006887	exocytosis	4.42e-02	1.00e+00	4.472	1	1	44
GO:0032481	positive regulation of type I interferon production	4.81e-02	1.00e+00	4.347	1	3	48
GO:0006368	transcription elongation from RNA polymerase II promoter	5.20e-02	1.00e+00	4.231	1	8	52
GO:0006289	nucleotide-excision repair	5.30e-02	1.00e+00	4.204	1	6	53
GO:0045666	positive regulation of neuron differentiation	5.30e-02	1.00e+00	4.204	1	3	53
GO:0005654	nucleoplasm	5.35e-02	1.00e+00	1.742	3	68	876
GO:0042826	histone deacetylase binding	5.79e-02	1.00e+00	4.073	1	5	58
GO:0071013	catalytic step 2 spliceosome	6.08e-02	1.00e+00	4.001	1	5	61
GO:0003677	DNA binding	6.50e-02	1.00e+00	1.629	3	52	947
GO:0016032	viral process	6.83e-02	1.00e+00	2.190	2	30	428
GO:0030308	negative regulation of cell growth	6.94e-02	1.00e+00	3.802	1	3	70
GO:0030496	midbody	7.23e-02	1.00e+00	3.742	1	6	73
GO:0005515	protein binding	7.32e-02	1.00e+00	0.729	7	198	4124
GO:0051056	regulation of small GTPase mediated signal transduction	7.52e-02	1.00e+00	3.684	1	2	76
GO:0005634	nucleus	7.55e-02	1.00e+00	0.852	6	158	3246
GO:0005938	cell cortex	7.61e-02	1.00e+00	3.665	1	6	77
GO:0030529	ribonucleoprotein complex	8.09e-02	1.00e+00	3.574	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	8.19e-02	1.00e+00	3.556	1	2	83
GO:0045202	synapse	8.19e-02	1.00e+00	3.556	1	3	83
GO:0030027	lamellipodium	8.66e-02	1.00e+00	3.472	1	3	88
GO:0061024	membrane organization	8.75e-02	1.00e+00	3.456	1	2	89
GO:0030036	actin cytoskeleton organization	8.85e-02	1.00e+00	3.440	1	4	90
GO:0005737	cytoplasm	1.03e-01	1.00e+00	0.891	5	127	2633
GO:0007179	transforming growth factor beta receptor signaling pathway	1.04e-01	1.00e+00	3.190	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.05e-01	1.00e+00	3.177	1	2	108
GO:0042981	regulation of apoptotic process	1.09e-01	1.00e+00	3.124	1	4	112
GO:0043005	neuron projection	1.10e-01	1.00e+00	3.111	1	6	113
GO:0007049	cell cycle	1.12e-01	1.00e+00	3.086	1	8	115
GO:0003924	GTPase activity	1.15e-01	1.00e+00	3.037	1	7	119
GO:0006184	GTP catabolic process	1.25e-01	1.00e+00	2.909	1	7	130
GO:0007165	signal transduction	1.28e-01	1.00e+00	1.660	2	24	618
GO:0030168	platelet activation	1.35e-01	1.00e+00	2.792	1	5	141
GO:0044212	transcription regulatory region DNA binding	1.37e-01	1.00e+00	2.772	1	13	143
GO:0005739	mitochondrion	1.43e-01	1.00e+00	1.567	2	32	659
GO:0006367	transcription initiation from RNA polymerase II promoter	1.53e-01	1.00e+00	2.601	1	18	161
GO:0006355	regulation of transcription, DNA-templated	1.63e-01	1.00e+00	1.450	2	31	715
GO:0007264	small GTPase mediated signal transduction	1.65e-01	1.00e+00	2.489	1	8	174
GO:0005575	cellular_component	1.76e-01	1.00e+00	2.385	1	4	187
GO:0005856	cytoskeleton	1.78e-01	1.00e+00	2.362	1	8	190
GO:0005743	mitochondrial inner membrane	1.84e-01	1.00e+00	2.309	1	9	197
GO:0005525	GTP binding	1.84e-01	1.00e+00	2.309	1	12	197
GO:0048011	neurotrophin TRK receptor signaling pathway	1.86e-01	1.00e+00	2.295	1	8	199
GO:0015031	protein transport	1.90e-01	1.00e+00	2.266	1	10	203
GO:0006281	DNA repair	1.90e-01	1.00e+00	2.266	1	24	203
GO:0044822	poly(A) RNA binding	1.95e-01	1.00e+00	1.289	2	45	799
GO:0019899	enzyme binding	1.95e-01	1.00e+00	2.217	1	7	210
GO:0030054	cell junction	2.02e-01	1.00e+00	2.163	1	5	218
GO:0007411	axon guidance	2.18e-01	1.00e+00	2.043	1	8	237
GO:0008283	cell proliferation	2.20e-01	1.00e+00	2.031	1	8	239
GO:0003723	RNA binding	2.26e-01	1.00e+00	1.983	1	22	247
GO:0070062	extracellular vesicular exosome	2.29e-01	1.00e+00	0.836	3	51	1641
GO:0005524	ATP binding	2.31e-01	1.00e+00	1.131	2	37	892
GO:0008150	biological_process	2.45e-01	1.00e+00	1.855	1	3	270
GO:0008285	negative regulation of cell proliferation	2.50e-01	1.00e+00	1.818	1	11	277
GO:0009986	cell surface	2.61e-01	1.00e+00	1.747	1	5	291
GO:0003674	molecular_function	2.66e-01	1.00e+00	1.717	1	4	297
GO:0005829	cytosol	2.72e-01	1.00e+00	0.713	3	88	1787
GO:0045892	negative regulation of transcription, DNA-templated	2.81e-01	1.00e+00	1.623	1	17	317
GO:0007596	blood coagulation	2.98e-01	1.00e+00	1.526	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	2.99e-01	1.00e+00	1.518	1	23	341
GO:0045893	positive regulation of transcription, DNA-templated	3.26e-01	1.00e+00	1.373	1	21	377
GO:0016020	membrane	3.56e-01	1.00e+00	0.694	2	56	1207
GO:0045087	innate immune response	3.78e-01	1.00e+00	1.111	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.099	1	29	456
GO:0005887	integral component of plasma membrane	4.55e-01	1.00e+00	0.764	1	8	575
GO:0005886	plasma membrane	5.70e-01	1.00e+00	0.131	2	46	1784
GO:0006351	transcription, DNA-templated	6.89e-01	1.00e+00	-0.140	1	47	1076
GO:0005730	nucleolus	7.36e-01	1.00e+00	-0.318	1	74	1217

chia-Fav

reg-snw-11333

Statistics

Genes (10)

Interactions (10)

Related GO terms (139)