reg-snw-1062

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.228	2.06e-07	3.94e-02	3.01e-02

chia-screen-data-Fav-reg-snw-1062 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
EXO1	9156	3	-1.521	2.312	159	TF	-	-
FBXL6	26233	28	-2.253	2.689	22	-	Yes	-
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
FOXM1	2305	9	-1.669	2.412	210	TF	-	-
SHFM1	7979	7	-2.366	2.389	3	-	Yes	-
TRAIP	10293	13	-2.546	2.454	30	TF	Yes	-
ALKBH8	91801	8	-2.147	2.410	5	-	Yes	-
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
[ CENPE ]	1062	1	-1.298	2.228	25	-	-	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes

Interactions (22)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CENPA	1058	FBXL6	26233	pd	>	reg.ITFP.txt: no annot
CENPA	1058	FOXM1	2305	pd	<>	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	ALKBH8	91801	pd	>	reg.ITFP.txt: no annot
EXO1	9156	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
EXO1	9156	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
CENPE	1062	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
FOXM1	2305	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
FOXM1	2305	SHFM1	7979	pd	>	reg.ITFP.txt: no annot
CENPE	1062	EXO1	9156	pd	<	reg.ITFP.txt: no annot
CENPA	1058	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
TRAIP	10293	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
FOXM1	2305	EXO1	9156	pd	<>	reg.ITFP.txt: no annot
CENPA	1058	EXO1	9156	pd	<>	reg.ITFP.txt: no annot
CENPA	1058	CENPE	1062	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
FOXM1	2305	TRAIP	10293	pd	<>	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
CENPE	1062	FOXM1	2305	pd	<	reg.ITFP.txt: no annot
CENPA	1058	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot

Related GO terms (182)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	2.20e-06	2.15e-02	9.347	2	2	2
GO:0000778	condensed nuclear chromosome kinetochore	6.60e-06	6.45e-02	8.762	2	2	3
GO:0000775	chromosome, centromeric region	3.02e-05	2.95e-01	5.574	3	6	41
GO:0008409	5'-3' exonuclease activity	4.60e-05	4.50e-01	7.539	2	2	7
GO:0051382	kinetochore assembly	4.60e-05	4.50e-01	7.539	2	2	7
GO:0006479	protein methylation	1.20e-04	1.00e+00	6.887	2	2	11
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	4.55e-04	1.00e+00	5.954	2	2	21
GO:0035312	5'-3' exodeoxyribonuclease activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0016149	translation release factor activity, codon specific	1.54e-03	1.00e+00	9.347	1	1	1
GO:0016300	tRNA (uracil) methyltransferase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0051908	double-stranded DNA 5'-3' exodeoxyribonuclease activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0000939	condensed chromosome inner kinetochore	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008079	translation termination factor activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0048256	flap endonuclease activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0045145	single-stranded DNA 5'-3' exodeoxyribonuclease activity	3.07e-03	1.00e+00	8.347	1	1	2
GO:0007079	mitotic chromosome movement towards spindle pole	3.07e-03	1.00e+00	8.347	1	1	2
GO:2000781	positive regulation of double-strand break repair	3.07e-03	1.00e+00	8.347	1	1	2
GO:0008611	ether lipid biosynthetic process	3.07e-03	1.00e+00	8.347	1	1	2
GO:0005515	protein binding	3.33e-03	1.00e+00	0.922	12	198	4124
GO:0006415	translational termination	4.07e-03	1.00e+00	4.369	2	2	63
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	4.60e-03	1.00e+00	7.762	1	1	3
GO:0036123	histone H3-K9 dimethylation	4.60e-03	1.00e+00	7.762	1	1	3
GO:0002098	tRNA wobble uridine modification	4.60e-03	1.00e+00	7.762	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	4.60e-03	1.00e+00	7.762	1	1	3
GO:0003723	RNA binding	5.81e-03	1.00e+00	2.983	3	22	247
GO:0097452	GAIT complex	6.13e-03	1.00e+00	7.347	1	2	4
GO:0006449	regulation of translational termination	6.13e-03	1.00e+00	7.347	1	1	4
GO:0030071	regulation of mitotic metaphase/anaphase transition	6.13e-03	1.00e+00	7.347	1	2	4
GO:0006333	chromatin assembly or disassembly	6.13e-03	1.00e+00	7.347	1	1	4
GO:0036124	histone H3-K9 trimethylation	6.13e-03	1.00e+00	7.347	1	2	4
GO:0043515	kinetochore binding	6.13e-03	1.00e+00	7.347	1	2	4
GO:0071156	regulation of cell cycle arrest	6.13e-03	1.00e+00	7.347	1	2	4
GO:1990023	mitotic spindle midzone	6.13e-03	1.00e+00	7.347	1	1	4
GO:0030529	ribonucleoprotein complex	6.81e-03	1.00e+00	3.989	2	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.14e-03	1.00e+00	3.954	2	5	84
GO:0004521	endoribonuclease activity	7.66e-03	1.00e+00	7.025	1	1	5
GO:0008610	lipid biosynthetic process	7.66e-03	1.00e+00	7.025	1	1	5
GO:0006398	histone mRNA 3'-end processing	7.66e-03	1.00e+00	7.025	1	1	5
GO:0090344	negative regulation of cell aging	7.66e-03	1.00e+00	7.025	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	7.66e-03	1.00e+00	7.025	1	2	5
GO:0032873	negative regulation of stress-activated MAPK cascade	7.66e-03	1.00e+00	7.025	1	1	5
GO:0000779	condensed chromosome, centromeric region	7.66e-03	1.00e+00	7.025	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	7.66e-03	1.00e+00	7.025	1	1	5
GO:0004523	RNA-DNA hybrid ribonuclease activity	7.66e-03	1.00e+00	7.025	1	1	5
GO:0043566	structure-specific DNA binding	9.18e-03	1.00e+00	6.762	1	1	6
GO:0042754	negative regulation of circadian rhythm	9.18e-03	1.00e+00	6.762	1	2	6
GO:0046974	histone methyltransferase activity (H3-K9 specific)	9.18e-03	1.00e+00	6.762	1	1	6
GO:0000940	condensed chromosome outer kinetochore	9.18e-03	1.00e+00	6.762	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	9.18e-03	1.00e+00	6.762	1	2	6
GO:0016446	somatic hypermutation of immunoglobulin genes	9.18e-03	1.00e+00	6.762	1	1	6
GO:0002455	humoral immune response mediated by circulating immunoglobulin	9.18e-03	1.00e+00	6.762	1	1	6
GO:0046578	regulation of Ras protein signal transduction	9.18e-03	1.00e+00	6.762	1	1	6
GO:0007140	male meiosis	1.07e-02	1.00e+00	6.539	1	1	7
GO:0000780	condensed nuclear chromosome, centromeric region	1.07e-02	1.00e+00	6.539	1	1	7
GO:0000278	mitotic cell cycle	1.12e-02	1.00e+00	2.637	3	28	314
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	1.22e-02	1.00e+00	6.347	1	1	8
GO:0071949	FAD binding	1.22e-02	1.00e+00	6.347	1	1	8
GO:0030488	tRNA methylation	1.37e-02	1.00e+00	6.177	1	2	9
GO:0006379	mRNA cleavage	1.37e-02	1.00e+00	6.177	1	2	9
GO:0032039	integrator complex	1.37e-02	1.00e+00	6.177	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.37e-02	1.00e+00	6.177	1	3	9
GO:0008143	poly(A) binding	1.53e-02	1.00e+00	6.025	1	2	10
GO:0000398	mRNA splicing, via spliceosome	1.60e-02	1.00e+00	3.347	2	15	128
GO:0007080	mitotic metaphase plate congression	1.68e-02	1.00e+00	5.887	1	1	11
GO:0000132	establishment of mitotic spindle orientation	1.83e-02	1.00e+00	5.762	1	2	12
GO:0004527	exonuclease activity	1.83e-02	1.00e+00	5.762	1	4	12
GO:0045190	isotype switching	1.98e-02	1.00e+00	5.646	1	1	13
GO:2000377	regulation of reactive oxygen species metabolic process	1.98e-02	1.00e+00	5.646	1	1	13
GO:0000738	DNA catabolic process, exonucleolytic	1.98e-02	1.00e+00	5.646	1	1	13
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	2.13e-02	1.00e+00	5.539	1	1	14
GO:0005782	peroxisomal matrix	2.43e-02	1.00e+00	5.347	1	1	16
GO:0008380	RNA splicing	2.58e-02	1.00e+00	2.980	2	21	165
GO:0043022	ribosome binding	2.58e-02	1.00e+00	5.259	1	2	17
GO:0006298	mismatch repair	2.58e-02	1.00e+00	5.259	1	1	17
GO:0006378	mRNA polyadenylation	2.73e-02	1.00e+00	5.177	1	3	18
GO:0004842	ubiquitin-protein transferase activity	3.00e-02	1.00e+00	2.863	2	17	179
GO:0034080	CENP-A containing nucleosome assembly	3.03e-02	1.00e+00	5.025	1	2	20
GO:0071346	cellular response to interferon-gamma	3.03e-02	1.00e+00	5.025	1	2	20
GO:0051321	meiotic cell cycle	3.03e-02	1.00e+00	5.025	1	1	20
GO:0005720	nuclear heterochromatin	3.03e-02	1.00e+00	5.025	1	3	20
GO:0016567	protein ubiquitination	3.28e-02	1.00e+00	2.792	2	14	188
GO:0000049	tRNA binding	3.48e-02	1.00e+00	4.823	1	2	23
GO:0000976	transcription regulatory region sequence-specific DNA binding	3.77e-02	1.00e+00	4.703	1	3	25
GO:0006281	DNA repair	3.78e-02	1.00e+00	2.681	2	24	203
GO:0005057	receptor signaling protein activity	3.92e-02	1.00e+00	4.646	1	2	26
GO:0005654	nucleoplasm	3.94e-02	1.00e+00	1.572	4	68	876
GO:0000737	DNA catabolic process, endonucleolytic	4.37e-02	1.00e+00	4.489	1	2	29
GO:0005778	peroxisomal membrane	4.37e-02	1.00e+00	4.489	1	3	29
GO:0090305	nucleic acid phosphodiester bond hydrolysis	4.66e-02	1.00e+00	4.392	1	6	31
GO:0005871	kinesin complex	4.66e-02	1.00e+00	4.392	1	3	31
GO:0017148	negative regulation of translation	4.95e-02	1.00e+00	4.302	1	5	33
GO:0000786	nucleosome	5.10e-02	1.00e+00	4.259	1	2	34
GO:0031124	mRNA 3'-end processing	5.25e-02	1.00e+00	4.217	1	4	35
GO:0045860	positive regulation of protein kinase activity	5.54e-02	1.00e+00	4.137	1	2	37
GO:0003682	chromatin binding	5.58e-02	1.00e+00	2.369	2	15	252
GO:0006369	termination of RNA polymerase II transcription	5.68e-02	1.00e+00	4.099	1	5	38
GO:0048511	rhythmic process	5.68e-02	1.00e+00	4.099	1	5	38
GO:0003777	microtubule motor activity	5.83e-02	1.00e+00	4.061	1	3	39
GO:0007018	microtubule-based movement	5.83e-02	1.00e+00	4.061	1	2	39
GO:0006396	RNA processing	5.98e-02	1.00e+00	4.025	1	4	40
GO:0000724	double-strand break repair via homologous recombination	6.27e-02	1.00e+00	3.954	1	5	42
GO:0006406	mRNA export from nucleus	6.55e-02	1.00e+00	3.887	1	7	44
GO:0001570	vasculogenesis	6.70e-02	1.00e+00	3.855	1	2	45
GO:0000502	proteasome complex	6.99e-02	1.00e+00	3.792	1	3	47
GO:0001558	regulation of cell growth	7.27e-02	1.00e+00	3.732	1	2	49
GO:0005777	peroxisome	7.42e-02	1.00e+00	3.703	1	2	50
GO:0006310	DNA recombination	7.42e-02	1.00e+00	3.703	1	8	50
GO:0006334	nucleosome assembly	7.56e-02	1.00e+00	3.674	1	4	51
GO:0055114	oxidation-reduction process	7.95e-02	1.00e+00	2.080	2	9	308
GO:0000776	kinetochore	8.13e-02	1.00e+00	3.565	1	8	55
GO:0006338	chromatin remodeling	8.13e-02	1.00e+00	3.565	1	7	55
GO:0005694	chromosome	8.13e-02	1.00e+00	3.565	1	4	55
GO:0045892	negative regulation of transcription, DNA-templated	8.35e-02	1.00e+00	2.038	2	17	317
GO:0000785	chromatin	8.70e-02	1.00e+00	3.464	1	6	59
GO:0071013	catalytic step 2 spliceosome	8.98e-02	1.00e+00	3.416	1	5	61
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	9.40e-02	1.00e+00	3.347	1	3	64
GO:0006366	transcription from RNA polymerase II promoter	9.47e-02	1.00e+00	1.933	2	23	341
GO:0008270	zinc ion binding	9.56e-02	1.00e+00	1.426	3	39	727
GO:0001889	liver development	1.04e-01	1.00e+00	3.197	1	4	71
GO:0030496	midbody	1.07e-01	1.00e+00	3.157	1	6	73
GO:0051726	regulation of cell cycle	1.07e-01	1.00e+00	3.157	1	3	73
GO:0001649	osteoblast differentiation	1.08e-01	1.00e+00	3.137	1	5	74
GO:0015630	microtubule cytoskeleton	1.09e-01	1.00e+00	3.118	1	5	75
GO:0071456	cellular response to hypoxia	1.11e-01	1.00e+00	3.099	1	2	76
GO:0042127	regulation of cell proliferation	1.16e-01	1.00e+00	3.025	1	4	80
GO:0044822	poly(A) RNA binding	1.19e-01	1.00e+00	1.289	3	45	799
GO:0044255	cellular lipid metabolic process	1.28e-01	1.00e+00	2.871	1	2	89
GO:0005506	iron ion binding	1.32e-01	1.00e+00	2.823	1	4	92
GO:0016032	viral process	1.38e-01	1.00e+00	1.605	2	30	428
GO:0000086	G2/M transition of mitotic cell cycle	1.39e-01	1.00e+00	2.747	1	7	97
GO:0008017	microtubule binding	1.39e-01	1.00e+00	2.747	1	9	97
GO:0016887	ATPase activity	1.43e-01	1.00e+00	2.703	1	5	100
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.53e-01	1.00e+00	1.514	2	29	456
GO:0007049	cell cycle	1.63e-01	1.00e+00	2.501	1	8	115
GO:0003924	GTPase activity	1.68e-01	1.00e+00	2.452	1	7	119
GO:0006974	cellular response to DNA damage stimulus	1.71e-01	1.00e+00	2.428	1	11	121
GO:0003677	DNA binding	1.72e-01	1.00e+00	1.044	3	52	947
GO:0000082	G1/S transition of mitotic cell cycle	1.76e-01	1.00e+00	2.381	1	4	125
GO:0006184	GTP catabolic process	1.82e-01	1.00e+00	2.324	1	7	130
GO:0010467	gene expression	1.97e-01	1.00e+00	1.283	2	49	535
GO:0044212	transcription regulatory region DNA binding	1.99e-01	1.00e+00	2.187	1	13	143
GO:0005622	intracellular	2.01e-01	1.00e+00	2.167	1	2	145
GO:0016874	ligase activity	2.02e-01	1.00e+00	2.157	1	11	146
GO:0005874	microtubule	2.23e-01	1.00e+00	1.998	1	10	163
GO:0016071	mRNA metabolic process	2.32e-01	1.00e+00	1.937	1	10	170
GO:0000166	nucleotide binding	2.39e-01	1.00e+00	1.887	1	13	176
GO:0006412	translation	2.41e-01	1.00e+00	1.871	1	12	178
GO:0008152	metabolic process	2.46e-01	1.00e+00	1.839	1	6	182
GO:0016070	RNA metabolic process	2.53e-01	1.00e+00	1.792	1	10	188
GO:0005525	GTP binding	2.64e-01	1.00e+00	1.724	1	12	197
GO:0035556	intracellular signal transduction	2.66e-01	1.00e+00	1.710	1	5	199
GO:0030154	cell differentiation	2.72e-01	1.00e+00	1.674	1	5	204
GO:0016020	membrane	2.81e-01	1.00e+00	0.694	3	56	1207
GO:0007275	multicellular organismal development	2.83e-01	1.00e+00	1.605	1	9	214
GO:0005730	nucleolus	2.85e-01	1.00e+00	0.682	3	74	1217
GO:0043231	intracellular membrane-bounded organelle	2.87e-01	1.00e+00	1.578	1	8	218
GO:0005829	cytosol	2.89e-01	1.00e+00	0.543	4	88	1787
GO:0006200	ATP catabolic process	2.89e-01	1.00e+00	1.572	1	13	219
GO:0019901	protein kinase binding	3.03e-01	1.00e+00	1.489	1	8	232
GO:0008283	cell proliferation	3.11e-01	1.00e+00	1.446	1	8	239
GO:0006508	proteolysis	3.37e-01	1.00e+00	1.302	1	11	264
GO:0046982	protein heterodimerization activity	3.38e-01	1.00e+00	1.297	1	11	265
GO:0043565	sequence-specific DNA binding	3.49e-01	1.00e+00	1.243	1	8	275
GO:0008284	positive regulation of cell proliferation	3.53e-01	1.00e+00	1.222	1	8	279
GO:0005634	nucleus	3.79e-01	1.00e+00	0.267	6	158	3246
GO:0007596	blood coagulation	4.12e-01	1.00e+00	0.941	1	13	339
GO:0048471	perinuclear region of cytoplasm	4.16e-01	1.00e+00	0.920	1	11	344
GO:0044267	cellular protein metabolic process	4.24e-01	1.00e+00	0.887	1	14	352
GO:0046872	metal ion binding	4.28e-01	1.00e+00	0.479	2	24	934
GO:0045893	positive regulation of transcription, DNA-templated	4.46e-01	1.00e+00	0.788	1	21	377
GO:0005783	endoplasmic reticulum	4.50e-01	1.00e+00	0.773	1	12	381
GO:0006915	apoptotic process	4.76e-01	1.00e+00	0.664	1	15	411
GO:0006351	transcription, DNA-templated	5.04e-01	1.00e+00	0.275	2	47	1076
GO:0003700	sequence-specific DNA binding transcription factor activity	6.02e-01	1.00e+00	0.162	1	22	582
GO:0007165	signal transduction	6.25e-01	1.00e+00	0.075	1	24	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.41e-01	1.00e+00	0.016	1	29	644
GO:0005739	mitochondrion	6.50e-01	1.00e+00	-0.018	1	32	659
GO:0006355	regulation of transcription, DNA-templated	6.81e-01	1.00e+00	-0.135	1	31	715
GO:0044281	small molecule metabolic process	7.43e-01	1.00e+00	-0.375	1	35	844
GO:0005524	ATP binding	7.63e-01	1.00e+00	-0.454	1	37	892
GO:0005737	cytoplasm	8.13e-01	1.00e+00	-0.431	3	127	2633

chia-Fav

reg-snw-1062

Statistics

Genes (15)

Interactions (22)

Related GO terms (182)