int-snw-9650

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.847	1.22e-15	4.17e-04	3.05e-03

chia-screen-data-Fav-int-snw-9650 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
TUBB4A	10382	7	-2.312	2.975	88	Yes	-
EP300	2033	22	-2.274	3.120	415	Yes	Yes
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
TCP1	6950	10	-2.383	3.119	241	Yes	-
PRDX6	9588	2	-2.364	2.976	65	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
VARS	7407	2	-2.366	2.847	80	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
GSTP1	2950	3	-2.251	2.955	59	Yes	-
[ MTFR1 ]	9650	1	-1.375	2.847	4	-	-
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes
H1FX	8971	7	-2.421	3.504	35	Yes	Yes

Interactions (17)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EP300	2033	HNRNPU	3192	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo
DDIT3	1649	TCP1	6950	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	H1FX	8971	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
PSMD2	5708	VARS	7407	pp	--	int.I2D: BioGrid_Yeast
POU5F1	5460	TUBB4A	10382	pp	--	int.I2D: BioGrid
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	GSTP1	2950	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
PSMD2	5708	TCP1	6950	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow
DDIT3	1649	PRDX6	9588	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	TUBB4A	10382	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	MTFR1	9650	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
TCP1	6950	VARS	7407	pp	--	int.I2D: IntAct_Yeast
DDIT3	1649	EP300	2033	pp	--	int.Intact: MI:0915(physical association)
DDIT3	1649	VARS	7407	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
EP300	2033	YAP1	10413	pp	--	int.I2D: BioGrid

Related GO terms (289)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005829	cytosol	5.02e-05	7.24e-01	2.000	9	86	2496
GO:0042789	mRNA transcription from RNA polymerase II promoter	5.82e-05	8.39e-01	7.415	2	2	13
GO:0005654	nucleoplasm	1.90e-04	1.00e+00	2.621	6	64	1082
GO:0044212	transcription regulatory region DNA binding	4.07e-04	1.00e+00	4.308	3	17	168
GO:0051084	'de novo' posttranslational protein folding	4.91e-04	1.00e+00	5.906	2	5	37
GO:0070664	negative regulation of leukocyte proliferation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0035732	nitric oxide storage	9.01e-04	1.00e+00	10.116	1	1	1
GO:1901985	positive regulation of protein acetylation	9.01e-04	1.00e+00	10.116	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	9.01e-04	1.00e+00	10.116	1	1	1
GO:0043969	histone H2B acetylation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.01e-04	1.00e+00	10.116	1	1	1
GO:0097057	TRAF2-GSTP1 complex	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.01e-04	1.00e+00	10.116	1	1	1
GO:0070026	nitric oxide binding	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060177	regulation of angiotensin metabolic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:0035731	dinitrosyl-iron complex binding	9.01e-04	1.00e+00	10.116	1	1	1
GO:0035730	S-nitrosoglutathione binding	9.01e-04	1.00e+00	10.116	1	1	1
GO:2000629	negative regulation of miRNA metabolic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:0008134	transcription factor binding	1.18e-03	1.00e+00	3.782	3	18	242
GO:0004832	valine-tRNA ligase activity	1.80e-03	1.00e+00	9.116	1	1	2
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	1.80e-03	1.00e+00	9.116	1	1	2
GO:0060242	contact inhibition	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009890	negative regulation of biosynthetic process	1.80e-03	1.00e+00	9.116	1	1	2
GO:0006438	valyl-tRNA aminoacylation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009786	regulation of asymmetric cell division	1.80e-03	1.00e+00	9.116	1	1	2
GO:0090043	regulation of tubulin deacetylation	1.80e-03	1.00e+00	9.116	1	2	2
GO:0019207	kinase regulator activity	1.80e-03	1.00e+00	9.116	1	1	2
GO:0071389	cellular response to mineralocorticoid stimulus	1.80e-03	1.00e+00	9.116	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	1.80e-03	1.00e+00	9.116	1	1	2
GO:0014737	positive regulation of muscle atrophy	1.80e-03	1.00e+00	9.116	1	1	2
GO:0035984	cellular response to trichostatin A	1.80e-03	1.00e+00	9.116	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	1.80e-03	1.00e+00	9.116	1	1	2
GO:0010467	gene expression	2.34e-03	1.00e+00	2.730	4	45	669
GO:0035726	common myeloid progenitor cell proliferation	2.70e-03	1.00e+00	8.531	1	1	3
GO:0018076	N-terminal peptidyl-lysine acetylation	2.70e-03	1.00e+00	8.531	1	1	3
GO:0051920	peroxiredoxin activity	2.70e-03	1.00e+00	8.531	1	1	3
GO:0060913	cardiac cell fate determination	2.70e-03	1.00e+00	8.531	1	1	3
GO:0010560	positive regulation of glycoprotein biosynthetic process	2.70e-03	1.00e+00	8.531	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.70e-03	1.00e+00	8.531	1	1	3
GO:0003677	DNA binding	3.08e-03	1.00e+00	2.187	5	49	1218
GO:0097157	pre-mRNA intronic binding	3.60e-03	1.00e+00	8.116	1	1	4
GO:0018393	internal peptidyl-lysine acetylation	3.60e-03	1.00e+00	8.116	1	1	4
GO:0007021	tubulin complex assembly	3.60e-03	1.00e+00	8.116	1	1	4
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	3.60e-03	1.00e+00	8.116	1	1	4
GO:0033269	internode region of axon	3.60e-03	1.00e+00	8.116	1	1	4
GO:0001714	endodermal cell fate specification	4.50e-03	1.00e+00	7.794	1	1	5
GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	4.50e-03	1.00e+00	7.794	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	4.50e-03	1.00e+00	7.794	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.50e-03	1.00e+00	7.794	1	2	5
GO:0065004	protein-DNA complex assembly	4.50e-03	1.00e+00	7.794	1	1	5
GO:0060298	positive regulation of sarcomere organization	4.50e-03	1.00e+00	7.794	1	1	5
GO:0032025	response to cobalt ion	4.50e-03	1.00e+00	7.794	1	1	5
GO:0000278	mitotic cell cycle	4.62e-03	1.00e+00	3.090	3	15	391
GO:0032873	negative regulation of stress-activated MAPK cascade	5.40e-03	1.00e+00	7.531	1	2	6
GO:0070937	CRD-mediated mRNA stability complex	5.40e-03	1.00e+00	7.531	1	3	6
GO:0032691	negative regulation of interleukin-1 beta production	5.40e-03	1.00e+00	7.531	1	1	6
GO:0008432	JUN kinase binding	5.40e-03	1.00e+00	7.531	1	1	6
GO:0032930	positive regulation of superoxide anion generation	6.29e-03	1.00e+00	7.308	1	2	7
GO:0002161	aminoacyl-tRNA editing activity	6.29e-03	1.00e+00	7.308	1	2	7
GO:0002674	negative regulation of acute inflammatory response	6.29e-03	1.00e+00	7.308	1	1	7
GO:0006475	internal protein amino acid acetylation	6.29e-03	1.00e+00	7.308	1	1	7
GO:0000086	G2/M transition of mitotic cell cycle	6.43e-03	1.00e+00	4.028	2	4	136
GO:0006457	protein folding	7.09e-03	1.00e+00	3.956	2	7	143
GO:0032872	regulation of stress-activated MAPK cascade	7.19e-03	1.00e+00	7.116	1	1	8
GO:0001955	blood vessel maturation	7.19e-03	1.00e+00	7.116	1	1	8
GO:0006974	cellular response to DNA damage stimulus	7.87e-03	1.00e+00	3.877	2	7	151
GO:0044267	cellular protein metabolic process	7.89e-03	1.00e+00	2.812	3	20	474
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	8.09e-03	1.00e+00	6.946	1	1	9
GO:0006450	regulation of translational fidelity	8.09e-03	1.00e+00	6.946	1	2	9
GO:0035259	glucocorticoid receptor binding	8.09e-03	1.00e+00	6.946	1	1	9
GO:0045793	positive regulation of cell size	8.09e-03	1.00e+00	6.946	1	2	9
GO:0000302	response to reactive oxygen species	8.09e-03	1.00e+00	6.946	1	1	9
GO:0060765	regulation of androgen receptor signaling pathway	8.09e-03	1.00e+00	6.946	1	1	9
GO:0006983	ER overload response	8.09e-03	1.00e+00	6.946	1	1	9
GO:0005832	chaperonin-containing T-complex	8.09e-03	1.00e+00	6.946	1	2	9
GO:0002199	zona pellucida receptor complex	8.98e-03	1.00e+00	6.794	1	2	10
GO:0035413	positive regulation of catenin import into nucleus	8.98e-03	1.00e+00	6.794	1	2	10
GO:0016407	acetyltransferase activity	8.98e-03	1.00e+00	6.794	1	2	10
GO:0006355	regulation of transcription, DNA-templated	9.80e-03	1.00e+00	2.154	4	43	997
GO:0009395	phospholipid catabolic process	9.87e-03	1.00e+00	6.656	1	1	11
GO:0045662	negative regulation of myoblast differentiation	9.87e-03	1.00e+00	6.656	1	3	11
GO:0043923	positive regulation by host of viral transcription	9.87e-03	1.00e+00	6.656	1	1	11
GO:0004623	phospholipase A2 activity	9.87e-03	1.00e+00	6.656	1	1	11
GO:0033160	positive regulation of protein import into nucleus, translocation	9.87e-03	1.00e+00	6.656	1	3	11
GO:0042975	peroxisome proliferator activated receptor binding	9.87e-03	1.00e+00	6.656	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	9.87e-03	1.00e+00	6.656	1	4	11
GO:0005667	transcription factor complex	1.05e-02	1.00e+00	3.664	2	17	175
GO:0003714	transcription corepressor activity	1.08e-02	1.00e+00	3.640	2	11	178
GO:0005838	proteasome regulatory particle	1.08e-02	1.00e+00	6.531	1	1	12
GO:0035198	miRNA binding	1.08e-02	1.00e+00	6.531	1	1	12
GO:0000266	mitochondrial fission	1.08e-02	1.00e+00	6.531	1	1	12
GO:0005515	protein binding	1.11e-02	1.00e+00	0.881	10	198	6024
GO:0043508	negative regulation of JUN kinase activity	1.17e-02	1.00e+00	6.415	1	1	13
GO:0071480	cellular response to gamma radiation	1.17e-02	1.00e+00	6.415	1	1	13
GO:0016746	transferase activity, transferring acyl groups	1.17e-02	1.00e+00	6.415	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.17e-02	1.00e+00	6.415	1	2	13
GO:0043409	negative regulation of MAPK cascade	1.17e-02	1.00e+00	6.415	1	2	13
GO:0004602	glutathione peroxidase activity	1.17e-02	1.00e+00	6.415	1	1	13
GO:0030234	enzyme regulator activity	1.17e-02	1.00e+00	6.415	1	2	13
GO:0044822	poly(A) RNA binding	1.20e-02	1.00e+00	2.071	4	50	1056
GO:0016209	antioxidant activity	1.26e-02	1.00e+00	6.308	1	2	14
GO:0070542	response to fatty acid	1.26e-02	1.00e+00	6.308	1	1	14
GO:0000242	pericentriolar material	1.26e-02	1.00e+00	6.308	1	1	14
GO:0032993	protein-DNA complex	1.26e-02	1.00e+00	6.308	1	2	14
GO:0001824	blastocyst development	1.34e-02	1.00e+00	6.209	1	2	15
GO:1990090	cellular response to nerve growth factor stimulus	1.34e-02	1.00e+00	6.209	1	1	15
GO:0042176	regulation of protein catabolic process	1.43e-02	1.00e+00	6.116	1	2	16
GO:0043209	myelin sheath	1.43e-02	1.00e+00	6.116	1	1	16
GO:0009060	aerobic respiration	1.52e-02	1.00e+00	6.028	1	1	17
GO:0070372	regulation of ERK1 and ERK2 cascade	1.52e-02	1.00e+00	6.028	1	2	17
GO:0022624	proteasome accessory complex	1.52e-02	1.00e+00	6.028	1	1	17
GO:0042744	hydrogen peroxide catabolic process	1.61e-02	1.00e+00	5.946	1	1	18
GO:0045773	positive regulation of axon extension	1.61e-02	1.00e+00	5.946	1	1	18
GO:0033613	activating transcription factor binding	1.61e-02	1.00e+00	5.946	1	3	18
GO:0004364	glutathione transferase activity	1.61e-02	1.00e+00	5.946	1	1	18
GO:0035257	nuclear hormone receptor binding	1.70e-02	1.00e+00	5.868	1	1	19
GO:0071549	cellular response to dexamethasone stimulus	1.79e-02	1.00e+00	5.794	1	3	20
GO:0010942	positive regulation of cell death	1.79e-02	1.00e+00	5.794	1	1	20
GO:0032757	positive regulation of interleukin-8 production	1.79e-02	1.00e+00	5.794	1	1	20
GO:1901687	glutathione derivative biosynthetic process	1.79e-02	1.00e+00	5.794	1	1	20
GO:0003713	transcription coactivator activity	1.86e-02	1.00e+00	3.227	2	24	237
GO:0032967	positive regulation of collagen biosynthetic process	1.88e-02	1.00e+00	5.723	1	3	21
GO:0045862	positive regulation of proteolysis	1.88e-02	1.00e+00	5.723	1	2	21
GO:0000123	histone acetyltransferase complex	1.88e-02	1.00e+00	5.723	1	6	21
GO:0003823	antigen binding	1.97e-02	1.00e+00	5.656	1	2	22
GO:0005720	nuclear heterochromatin	1.97e-02	1.00e+00	5.656	1	2	22
GO:0048147	negative regulation of fibroblast proliferation	1.97e-02	1.00e+00	5.656	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.97e-02	1.00e+00	5.656	1	2	22
GO:0005874	microtubule	2.04e-02	1.00e+00	3.156	2	7	249
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.05e-02	1.00e+00	5.592	1	1	23
GO:0043388	positive regulation of DNA binding	2.14e-02	1.00e+00	5.531	1	2	24
GO:0043425	bHLH transcription factor binding	2.14e-02	1.00e+00	5.531	1	1	24
GO:0051059	NF-kappaB binding	2.23e-02	1.00e+00	5.472	1	3	25
GO:0007339	binding of sperm to zona pellucida	2.23e-02	1.00e+00	5.472	1	2	25
GO:0003700	sequence-specific DNA binding transcription factor activity	2.25e-02	1.00e+00	2.251	3	39	699
GO:0035329	hippo signaling	2.32e-02	1.00e+00	5.415	1	5	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.32e-02	1.00e+00	5.415	1	1	26
GO:0051209	release of sequestered calcium ion into cytosol	2.32e-02	1.00e+00	5.415	1	1	26
GO:0048565	digestive tract development	2.32e-02	1.00e+00	5.415	1	2	26
GO:0032720	negative regulation of tumor necrosis factor production	2.41e-02	1.00e+00	5.361	1	2	27
GO:0034612	response to tumor necrosis factor	2.41e-02	1.00e+00	5.361	1	2	27
GO:0007017	microtubule-based process	2.41e-02	1.00e+00	5.361	1	2	27
GO:0006749	glutathione metabolic process	2.41e-02	1.00e+00	5.361	1	1	27
GO:0043967	histone H4 acetylation	2.41e-02	1.00e+00	5.361	1	1	27
GO:0051258	protein polymerization	2.41e-02	1.00e+00	5.361	1	2	27
GO:0050714	positive regulation of protein secretion	2.50e-02	1.00e+00	5.308	1	3	28
GO:0005634	nucleus	2.51e-02	1.00e+00	0.961	8	159	4559
GO:0007005	mitochondrion organization	2.67e-02	1.00e+00	5.209	1	1	30
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.67e-02	1.00e+00	5.209	1	1	30
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	2.67e-02	1.00e+00	5.209	1	2	30
GO:0042594	response to starvation	2.76e-02	1.00e+00	5.161	1	4	31
GO:0070373	negative regulation of ERK1 and ERK2 cascade	2.76e-02	1.00e+00	5.161	1	1	31
GO:0043407	negative regulation of MAP kinase activity	2.85e-02	1.00e+00	5.116	1	1	32
GO:0043491	protein kinase B signaling	2.85e-02	1.00e+00	5.116	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	2.85e-02	1.00e+00	5.116	1	2	32
GO:0001756	somitogenesis	2.94e-02	1.00e+00	5.071	1	1	33
GO:0071333	cellular response to glucose stimulus	2.94e-02	1.00e+00	5.071	1	1	33
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.09e-02	1.00e+00	2.077	3	41	789
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	3.11e-02	1.00e+00	4.986	1	2	35
GO:0001102	RNA polymerase II activating transcription factor binding	3.20e-02	1.00e+00	4.946	1	1	36
GO:0031490	chromatin DNA binding	3.37e-02	1.00e+00	4.868	1	2	38
GO:0032092	positive regulation of protein binding	3.37e-02	1.00e+00	4.868	1	2	38
GO:0050681	androgen receptor binding	3.37e-02	1.00e+00	4.868	1	1	38
GO:0046332	SMAD binding	3.55e-02	1.00e+00	4.794	1	2	40
GO:0071320	cellular response to cAMP	3.55e-02	1.00e+00	4.794	1	1	40
GO:0035019	somatic stem cell maintenance	3.55e-02	1.00e+00	4.794	1	6	40
GO:0007519	skeletal muscle tissue development	3.55e-02	1.00e+00	4.794	1	2	40
GO:0070301	cellular response to hydrogen peroxide	3.63e-02	1.00e+00	4.758	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	3.72e-02	1.00e+00	4.723	1	3	42
GO:0043565	sequence-specific DNA binding	3.76e-02	1.00e+00	2.681	2	11	346
GO:0004402	histone acetyltransferase activity	3.81e-02	1.00e+00	4.689	1	6	43
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.90e-02	1.00e+00	4.656	1	4	44
GO:0045727	positive regulation of translation	3.90e-02	1.00e+00	4.656	1	2	44
GO:0043966	histone H3 acetylation	3.98e-02	1.00e+00	4.624	1	5	45
GO:0001047	core promoter binding	3.98e-02	1.00e+00	4.624	1	5	45
GO:0044297	cell body	4.07e-02	1.00e+00	4.592	1	2	46
GO:0043525	positive regulation of neuron apoptotic process	4.07e-02	1.00e+00	4.592	1	4	46
GO:0001669	acrosomal vesicle	4.33e-02	1.00e+00	4.501	1	2	49
GO:0035690	cellular response to drug	4.33e-02	1.00e+00	4.501	1	3	49
GO:0006521	regulation of cellular amino acid metabolic process	4.42e-02	1.00e+00	4.472	1	1	50
GO:0006986	response to unfolded protein	4.42e-02	1.00e+00	4.472	1	4	50
GO:0034976	response to endoplasmic reticulum stress	4.50e-02	1.00e+00	4.443	1	2	51
GO:0045454	cell redox homeostasis	4.50e-02	1.00e+00	4.443	1	1	51
GO:0009611	response to wounding	4.59e-02	1.00e+00	4.415	1	5	52
GO:0007623	circadian rhythm	4.68e-02	1.00e+00	4.388	1	1	53
GO:0051592	response to calcium ion	4.85e-02	1.00e+00	4.334	1	1	55
GO:0002039	p53 binding	4.85e-02	1.00e+00	4.334	1	4	55
GO:0071300	cellular response to retinoic acid	4.85e-02	1.00e+00	4.334	1	1	55
GO:0043627	response to estrogen	4.93e-02	1.00e+00	4.308	1	5	56
GO:0070062	extracellular vesicular exosome	5.08e-02	1.00e+00	1.209	5	57	2400
GO:0000502	proteasome complex	5.11e-02	1.00e+00	4.258	1	3	58
GO:0006396	RNA processing	5.19e-02	1.00e+00	4.233	1	5	59
GO:0000786	nucleosome	5.19e-02	1.00e+00	4.233	1	2	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.19e-02	1.00e+00	4.233	1	6	59
GO:0008013	beta-catenin binding	5.28e-02	1.00e+00	4.209	1	9	60
GO:0006987	activation of signaling protein activity involved in unfolded protein response	5.36e-02	1.00e+00	4.185	1	2	61
GO:0032481	positive regulation of type I interferon production	5.36e-02	1.00e+00	4.185	1	6	61
GO:0043066	negative regulation of apoptotic process	5.43e-02	1.00e+00	2.388	2	16	424
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.53e-02	1.00e+00	4.138	1	4	63
GO:0005739	mitochondrion	5.60e-02	1.00e+00	1.738	3	23	998
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.62e-02	1.00e+00	4.116	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.71e-02	1.00e+00	4.093	1	2	65
GO:0006469	negative regulation of protein kinase activity	5.71e-02	1.00e+00	4.093	1	4	65
GO:0010468	regulation of gene expression	5.96e-02	1.00e+00	4.028	1	2	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.13e-02	1.00e+00	3.986	1	2	70
GO:0006334	nucleosome assembly	6.30e-02	1.00e+00	3.946	1	3	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.30e-02	1.00e+00	3.946	1	1	72
GO:0030324	lung development	6.30e-02	1.00e+00	3.946	1	1	72
GO:0000785	chromatin	6.39e-02	1.00e+00	3.926	1	6	73
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	6.47e-02	1.00e+00	3.906	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.47e-02	1.00e+00	3.906	1	2	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	6.56e-02	1.00e+00	3.887	1	1	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.56e-02	1.00e+00	3.887	1	1	75
GO:0001889	liver development	6.72e-02	1.00e+00	3.849	1	3	77
GO:0005929	cilium	6.72e-02	1.00e+00	3.849	1	2	77
GO:0071013	catalytic step 2 spliceosome	6.81e-02	1.00e+00	3.830	1	7	78
GO:0030968	endoplasmic reticulum unfolded protein response	6.89e-02	1.00e+00	3.812	1	2	79
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.89e-02	1.00e+00	3.812	1	2	79
GO:0071222	cellular response to lipopolysaccharide	7.06e-02	1.00e+00	3.776	1	4	81
GO:0009653	anatomical structure morphogenesis	7.23e-02	1.00e+00	3.741	1	2	83
GO:0009887	organ morphogenesis	7.48e-02	1.00e+00	3.689	1	5	86
GO:0090090	negative regulation of canonical Wnt signaling pathway	7.48e-02	1.00e+00	3.689	1	8	86
GO:0045471	response to ethanol	7.48e-02	1.00e+00	3.689	1	3	86
GO:0006979	response to oxidative stress	7.57e-02	1.00e+00	3.673	1	6	87
GO:0005200	structural constituent of cytoskeleton	7.90e-02	1.00e+00	3.608	1	6	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.99e-02	1.00e+00	3.592	1	1	92
GO:0001649	osteoblast differentiation	7.99e-02	1.00e+00	3.592	1	5	92
GO:0071456	cellular response to hypoxia	7.99e-02	1.00e+00	3.592	1	3	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	7.99e-02	1.00e+00	3.592	1	7	92
GO:0051082	unfolded protein binding	8.07e-02	1.00e+00	3.576	1	7	93
GO:0005770	late endosome	8.07e-02	1.00e+00	3.576	1	2	93
GO:0016032	viral process	8.15e-02	1.00e+00	2.055	2	26	534
GO:0007417	central nervous system development	8.32e-02	1.00e+00	3.531	1	5	96
GO:0051726	regulation of cell cycle	8.40e-02	1.00e+00	3.516	1	5	97
GO:0006915	apoptotic process	8.71e-02	1.00e+00	1.999	2	12	555
GO:0006805	xenobiotic metabolic process	8.90e-02	1.00e+00	3.429	1	2	103
GO:0001934	positive regulation of protein phosphorylation	8.98e-02	1.00e+00	3.415	1	5	104
GO:0016023	cytoplasmic membrane-bounded vesicle	9.07e-02	1.00e+00	3.401	1	8	105
GO:0005737	cytoplasm	9.60e-02	1.00e+00	0.821	6	124	3767
GO:0030529	ribonucleoprotein complex	9.64e-02	1.00e+00	3.308	1	5	112
GO:0000209	protein polyubiquitination	9.97e-02	1.00e+00	3.258	1	3	116
GO:0006325	chromatin organization	1.01e-01	1.00e+00	3.233	1	12	118
GO:0007219	Notch signaling pathway	1.03e-01	1.00e+00	3.209	1	5	120
GO:0005524	ATP binding	1.05e-01	1.00e+00	1.359	3	31	1298
GO:0007050	cell cycle arrest	1.06e-01	1.00e+00	3.161	1	5	124
GO:0031982	vesicle	1.12e-01	1.00e+00	3.082	1	3	131
GO:0016055	Wnt signaling pathway	1.18e-01	1.00e+00	3.007	1	4	138
GO:0007507	heart development	1.18e-01	1.00e+00	2.997	1	7	139
GO:0001666	response to hypoxia	1.26e-01	1.00e+00	2.896	1	7	149
GO:0000082	G1/S transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	3	149
GO:0042981	regulation of apoptotic process	1.27e-01	1.00e+00	2.887	1	4	150
GO:0000398	mRNA splicing, via spliceosome	1.38e-01	1.00e+00	2.758	1	15	164
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.39e-01	1.00e+00	2.749	1	12	165
GO:0034641	cellular nitrogen compound metabolic process	1.44e-01	1.00e+00	2.698	1	2	171
GO:0005764	lysosome	1.44e-01	1.00e+00	2.689	1	2	172
GO:0031625	ubiquitin protein ligase binding	1.49e-01	1.00e+00	2.640	1	5	178
GO:0032403	protein complex binding	1.53e-01	1.00e+00	2.600	1	6	183
GO:0006367	transcription initiation from RNA polymerase II promoter	1.54e-01	1.00e+00	2.592	1	22	184
GO:0003924	GTPase activity	1.64e-01	1.00e+00	2.494	1	7	197
GO:0005622	intracellular	1.71e-01	1.00e+00	2.422	1	6	207
GO:0006184	GTP catabolic process	1.77e-01	1.00e+00	2.374	1	7	214
GO:0016071	mRNA metabolic process	1.83e-01	1.00e+00	2.315	1	8	223
GO:0016020	membrane	1.87e-01	1.00e+00	0.986	3	46	1681
GO:0008380	RNA splicing	1.87e-01	1.00e+00	2.283	1	22	228
GO:0007399	nervous system development	1.89e-01	1.00e+00	2.264	1	6	231
GO:0043025	neuronal cell body	2.00e-01	1.00e+00	2.179	1	9	245
GO:0016070	RNA metabolic process	2.01e-01	1.00e+00	2.167	1	8	247
GO:0005615	extracellular space	2.12e-01	1.00e+00	1.213	2	20	957
GO:0005525	GTP binding	2.46e-01	1.00e+00	1.840	1	12	310
GO:0005813	centrosome	2.57e-01	1.00e+00	1.767	1	7	326
GO:0003682	chromatin binding	2.58e-01	1.00e+00	1.762	1	19	327
GO:0008283	cell proliferation	2.59e-01	1.00e+00	1.758	1	14	328
GO:0003723	RNA binding	2.68e-01	1.00e+00	1.698	1	18	342
GO:0046982	protein heterodimerization activity	2.93e-01	1.00e+00	1.546	1	8	380
GO:0044281	small molecule metabolic process	2.99e-01	1.00e+00	0.874	2	20	1211
GO:0009986	cell surface	3.08e-01	1.00e+00	1.465	1	9	402
GO:0045892	negative regulation of transcription, DNA-templated	3.15e-01	1.00e+00	1.426	1	24	413
GO:0006366	transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.405	1	30	419
GO:0055114	oxidation-reduction process	3.19e-01	1.00e+00	1.401	1	10	420
GO:0045893	positive regulation of transcription, DNA-templated	3.55e-01	1.00e+00	1.215	1	24	478
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.08e-01	1.00e+00	0.961	1	37	570
GO:0045087	innate immune response	4.22e-01	1.00e+00	0.896	1	15	596
GO:0005794	Golgi apparatus	4.30e-01	1.00e+00	0.863	1	9	610
GO:0005730	nucleolus	4.45e-01	1.00e+00	0.435	2	66	1641
GO:0008270	zinc ion binding	6.06e-01	1.00e+00	0.154	1	27	997
GO:0005886	plasma membrane	7.05e-01	1.00e+00	-0.219	2	49	2582
GO:0006351	transcription, DNA-templated	7.47e-01	1.00e+00	-0.382	1	57	1446

chia-Fav

int-snw-9650

Statistics

Genes (13)

Interactions (17)

Related GO terms (289)