int-snw-9221

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.033	1.03e-17	3.67e-05	5.46e-04

chia-screen-data-Fav-int-snw-9221 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
MED19	219541	30	-2.657	3.449	115	Yes	-
LUC7L3	51747	33	-3.523	3.449	18	Yes	-
MED24	9862	6	-2.482	3.033	39	Yes	-
MED13L	23389	12	-2.550	3.159	21	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
[ NOLC1 ]	9221	1	-1.985	3.033	23	-	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
MED24	9862	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
SRSF3	6428	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HCFC1	3054	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
LUC7L3	51747	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NOLC1	9221	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
MED13L	23389	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct

Related GO terms (99)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0001104	RNA polymerase II transcription cofactor activity	6.06e-07	8.75e-03	7.357	3	8	33
GO:0016592	mediator complex	7.27e-07	1.05e-02	7.272	3	10	35
GO:0006366	transcription from RNA polymerase II promoter	1.05e-06	1.52e-02	4.427	5	30	419
GO:0006357	regulation of transcription from RNA polymerase II promoter	3.17e-04	1.00e+00	4.357	3	23	264
GO:0060795	cell fate commitment involved in formation of primary germ layer	5.55e-04	1.00e+00	10.816	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	5.55e-04	1.00e+00	10.816	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	5.55e-04	1.00e+00	10.816	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	5.55e-04	1.00e+00	10.816	1	1	1
GO:0019046	release from viral latency	1.11e-03	1.00e+00	9.816	1	2	2
GO:0009786	regulation of asymmetric cell division	1.11e-03	1.00e+00	9.816	1	1	2
GO:0044822	poly(A) RNA binding	1.57e-03	1.00e+00	2.772	4	50	1056
GO:0060913	cardiac cell fate determination	1.66e-03	1.00e+00	9.231	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.66e-03	1.00e+00	9.231	1	1	3
GO:0005654	nucleoplasm	1.73e-03	1.00e+00	2.737	4	64	1082
GO:0007000	nucleolus organization	2.22e-03	1.00e+00	8.816	1	1	4
GO:0070461	SAGA-type complex	2.77e-03	1.00e+00	8.494	1	2	5
GO:0001714	endodermal cell fate specification	2.77e-03	1.00e+00	8.494	1	1	5
GO:0016607	nuclear speck	3.78e-03	1.00e+00	4.390	2	12	172
GO:0007049	cell cycle	3.86e-03	1.00e+00	4.373	2	6	174
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0043254	regulation of protein complex assembly	4.43e-03	1.00e+00	7.816	1	1	8
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	4.98e-03	1.00e+00	7.646	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	4.98e-03	1.00e+00	7.646	1	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	4.98e-03	1.00e+00	7.646	1	5	9
GO:0048188	Set1C/COMPASS complex	4.98e-03	1.00e+00	7.646	1	4	9
GO:0035413	positive regulation of catenin import into nucleus	5.53e-03	1.00e+00	7.494	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	6.09e-03	1.00e+00	7.357	1	4	11
GO:0008380	RNA splicing	6.54e-03	1.00e+00	3.983	2	22	228
GO:0035198	miRNA binding	6.64e-03	1.00e+00	7.231	1	1	12
GO:0042789	mRNA transcription from RNA polymerase II promoter	7.19e-03	1.00e+00	7.116	1	2	13
GO:0005685	U1 snRNP	7.74e-03	1.00e+00	7.009	1	1	14
GO:0030518	intracellular steroid hormone receptor signaling pathway	7.74e-03	1.00e+00	7.009	1	6	14
GO:0043981	histone H4-K5 acetylation	8.29e-03	1.00e+00	6.909	1	5	15
GO:0042809	vitamin D receptor binding	8.29e-03	1.00e+00	6.909	1	6	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	8.29e-03	1.00e+00	6.909	1	3	15
GO:0006376	mRNA splice site selection	8.29e-03	1.00e+00	6.909	1	1	15
GO:0001824	blastocyst development	8.29e-03	1.00e+00	6.909	1	2	15
GO:0043982	histone H4-K8 acetylation	8.29e-03	1.00e+00	6.909	1	5	15
GO:0043274	phospholipase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0043984	histone H4-K16 acetylation	1.05e-02	1.00e+00	6.568	1	5	19
GO:0000123	histone acetyltransferase complex	1.16e-02	1.00e+00	6.424	1	6	21
GO:0045787	positive regulation of cell cycle	1.21e-02	1.00e+00	6.357	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.21e-02	1.00e+00	6.357	1	4	22
GO:0016573	histone acetylation	1.27e-02	1.00e+00	6.293	1	2	23
GO:0046966	thyroid hormone receptor binding	1.43e-02	1.00e+00	6.116	1	6	26
GO:0071339	MLL1 complex	1.49e-02	1.00e+00	6.061	1	6	27
GO:0035019	somatic stem cell maintenance	2.20e-02	1.00e+00	5.494	1	6	40
GO:0030521	androgen receptor signaling pathway	2.25e-02	1.00e+00	5.459	1	5	41
GO:0031124	mRNA 3'-end processing	2.31e-02	1.00e+00	5.424	1	2	42
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	2.36e-02	1.00e+00	5.390	1	7	43
GO:0004402	histone acetyltransferase activity	2.36e-02	1.00e+00	5.390	1	6	43
GO:0003712	transcription cofactor activity	2.42e-02	1.00e+00	5.357	1	8	44
GO:0015030	Cajal body	2.42e-02	1.00e+00	5.357	1	2	44
GO:0006369	termination of RNA polymerase II transcription	2.47e-02	1.00e+00	5.324	1	2	45
GO:0019827	stem cell maintenance	2.58e-02	1.00e+00	5.261	1	7	47
GO:0009611	response to wounding	2.85e-02	1.00e+00	5.116	1	5	52
GO:0051291	protein heterooligomerization	3.06e-02	1.00e+00	5.009	1	4	56
GO:0006406	mRNA export from nucleus	3.33e-02	1.00e+00	4.885	1	4	61
GO:0010468	regulation of gene expression	3.71e-02	1.00e+00	4.729	1	2	68
GO:0003729	mRNA binding	3.93e-02	1.00e+00	4.646	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.03e-02	1.00e+00	4.607	1	4	74
GO:0009653	anatomical structure morphogenesis	4.51e-02	1.00e+00	4.441	1	2	83
GO:0050821	protein stabilization	4.78e-02	1.00e+00	4.357	1	3	88
GO:0010467	gene expression	4.99e-02	1.00e+00	2.430	2	45	669
GO:0006364	rRNA processing	5.10e-02	1.00e+00	4.261	1	3	94
GO:0005730	nucleolus	5.31e-02	1.00e+00	1.721	3	66	1641
GO:0003700	sequence-specific DNA binding transcription factor activity	5.41e-02	1.00e+00	2.367	2	39	699
GO:0006325	chromatin organization	6.36e-02	1.00e+00	3.933	1	12	118
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.72e-02	1.00e+00	2.192	2	41	789
GO:0005634	nucleus	7.14e-02	1.00e+00	0.984	5	159	4559
GO:0010628	positive regulation of gene expression	7.82e-02	1.00e+00	3.626	1	7	146
GO:0000398	mRNA splicing, via spliceosome	8.74e-02	1.00e+00	3.459	1	15	164
GO:0044212	transcription regulatory region DNA binding	8.95e-02	1.00e+00	3.424	1	17	168
GO:0005667	transcription factor complex	9.31e-02	1.00e+00	3.365	1	17	175
GO:0031625	ubiquitin protein ligase binding	9.46e-02	1.00e+00	3.340	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	9.76e-02	1.00e+00	3.293	1	22	184
GO:0004872	receptor activity	1.00e-01	1.00e+00	3.254	1	8	189
GO:0006355	regulation of transcription, DNA-templated	1.01e-01	1.00e+00	1.855	2	43	997
GO:0007067	mitotic nuclear division	1.19e-01	1.00e+00	2.990	1	6	227
GO:0003713	transcription coactivator activity	1.24e-01	1.00e+00	2.927	1	24	237
GO:0008134	transcription factor binding	1.27e-01	1.00e+00	2.897	1	18	242
GO:0043025	neuronal cell body	1.28e-01	1.00e+00	2.879	1	9	245
GO:0005737	cytoplasm	1.30e-01	1.00e+00	0.937	4	124	3767
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.799	1	13	259
GO:0003677	DNA binding	1.42e-01	1.00e+00	1.566	2	49	1218
GO:0005525	GTP binding	1.60e-01	1.00e+00	2.540	1	12	310
GO:0003682	chromatin binding	1.68e-01	1.00e+00	2.463	1	19	327
GO:0003723	RNA binding	1.75e-01	1.00e+00	2.398	1	18	342
GO:0043565	sequence-specific DNA binding	1.77e-01	1.00e+00	2.381	1	11	346
GO:0005925	focal adhesion	1.86e-01	1.00e+00	2.300	1	9	366
GO:0005515	protein binding	2.02e-01	1.00e+00	0.582	5	198	6024
GO:0045893	positive regulation of transcription, DNA-templated	2.36e-01	1.00e+00	1.915	1	24	478
GO:0042802	identical protein binding	2.39e-01	1.00e+00	1.897	1	19	484
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.76e-01	1.00e+00	1.661	1	37	570
GO:0005739	mitochondrion	4.37e-01	1.00e+00	0.853	1	23	998
GO:0005524	ATP binding	5.30e-01	1.00e+00	0.474	1	31	1298
GO:0016020	membrane	6.29e-01	1.00e+00	0.101	1	46	1681
GO:0005829	cytosol	7.81e-01	1.00e+00	-0.469	1	86	2496
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.518	1	49	2582

chia-Fav

int-snw-9221

Statistics

Genes (8)

Interactions (8)

Related GO terms (99)