Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 2.818 | 2.52e-15 | 5.92e-04 | 3.91e-03 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
PXN | 5829 | 19 | -2.554 | 3.193 | 206 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
APC | 324 | 13 | -2.293 | 3.004 | 353 | Yes | - |
NFRKB | 4798 | 48 | -3.129 | 3.108 | 23 | Yes | Yes |
SRSF3 | 6428 | 73 | -2.992 | 3.538 | 54 | Yes | - |
LDB2 | 9079 | 2 | -2.380 | 2.818 | 27 | Yes | - |
MVP | 9961 | 16 | -2.846 | 3.193 | 20 | Yes | Yes |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
[ SERPINH1 ] | 871 | 1 | -1.447 | 2.818 | 37 | - | - |
CTBP1 | 1487 | 2 | -1.678 | 2.818 | 95 | - | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
CTBP1 | 1487 | EP300 | 2033 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.Ravasi: -; int.HPRD: in vitro, in vivo |
NFRKB | 4798 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
PXN | 5829 | SRSF3 | 6428 | pp | -- | int.I2D: BIND |
APC | 324 | CTBP1 | 1487 | pp | -- | int.I2D: BCI, BioGrid, HPRD, Jorgensen_EphR, BIND; int.Ravasi: -; int.HPRD: in vitro, in vivo |
SERPINH1 | 871 | CTBP1 | 1487 | pp | -- | int.I2D: BioGrid |
APC | 324 | PXN | 5829 | pp | -- | int.I2D: MINT, MINT_Mouse; int.Mint: MI:0914(association) |
SERPINH1 | 871 | PXN | 5829 | pp | -- | int.I2D: BIND |
CTBP1 | 1487 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
POU5F1 | 5460 | SRSF3 | 6428 | pp | -- | int.I2D: BioGrid |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
PXN | 5829 | MVP | 9961 | pp | -- | int.I2D: BIND |
CTBP1 | 1487 | LDB2 | 9079 | pp | -- | int.Ravasi: - |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0035019 | somatic stem cell maintenance | 3.21e-06 | 4.63e-02 | 6.620 | 3 | 6 | 40 |
GO:0005667 | transcription factor complex | 6.47e-06 | 9.33e-02 | 4.905 | 4 | 17 | 175 |
GO:0008013 | beta-catenin binding | 1.10e-05 | 1.59e-01 | 6.035 | 3 | 9 | 60 |
GO:0001942 | hair follicle development | 3.10e-04 | 1.00e+00 | 6.227 | 2 | 2 | 35 |
GO:0008134 | transcription factor binding | 6.97e-04 | 1.00e+00 | 4.023 | 3 | 18 | 242 |
GO:0023057 | negative regulation of signaling | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:1901985 | positive regulation of protein acetylation | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0051435 | BH4 domain binding | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0042483 | negative regulation of odontogenesis | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0044089 | positive regulation of cellular component biogenesis | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0051171 | regulation of nitrogen compound metabolic process | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0072376 | protein activation cascade | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0034401 | regulation of transcription by chromatin organization | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0005634 | nucleus | 8.85e-04 | 1.00e+00 | 1.372 | 9 | 159 | 4559 |
GO:0060242 | contact inhibition | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0019901 | protein kinase binding | 1.52e-03 | 1.00e+00 | 3.633 | 3 | 18 | 317 |
GO:0090241 | negative regulation of histone H4 acetylation | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 2 | 2 |
GO:0044337 | canonical Wnt signaling pathway involved in positive regulation of apoptotic process | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 2 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0035984 | cellular response to trichostatin A | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0009798 | axis specification | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:0051726 | regulation of cell cycle | 2.37e-03 | 1.00e+00 | 4.757 | 2 | 5 | 97 |
GO:0097157 | pre-mRNA intronic binding | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0010669 | epithelial structure maintenance | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0038127 | ERBB signaling pathway | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0019887 | protein kinase regulator activity | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0006366 | transcription from RNA polymerase II promoter | 3.38e-03 | 1.00e+00 | 3.231 | 3 | 30 | 419 |
GO:0001714 | endodermal cell fate specification | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 2 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0032964 | collagen biosynthetic process | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0030027 | lamellipodium | 3.89e-03 | 1.00e+00 | 4.391 | 2 | 7 | 125 |
GO:0030858 | positive regulation of epithelial cell differentiation | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0006355 | regulation of transcription, DNA-templated | 5.05e-03 | 1.00e+00 | 2.395 | 4 | 43 | 997 |
GO:0007091 | metaphase/anaphase transition of mitotic cell cycle | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 2 | 7 |
GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0051988 | regulation of attachment of spindle microtubules to kinetochore | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 2 | 7 |
GO:0061099 | negative regulation of protein tyrosine kinase activity | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0030274 | LIM domain binding | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0006475 | internal protein amino acid acetylation | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0006974 | cellular response to DNA damage stimulus | 5.63e-03 | 1.00e+00 | 4.118 | 2 | 7 | 151 |
GO:0045670 | regulation of osteoclast differentiation | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0035067 | negative regulation of histone acetylation | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0007172 | signal complex assembly | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 1 | 8 |
GO:0060396 | growth hormone receptor signaling pathway | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 1 | 8 |
GO:0051604 | protein maturation | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0005654 | nucleoplasm | 6.78e-03 | 1.00e+00 | 2.277 | 4 | 64 | 1082 |
GO:0045667 | regulation of osteoblast differentiation | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 9 |
GO:0031953 | negative regulation of protein autophosphorylation | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 9 |
GO:0035259 | glucocorticoid receptor binding | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 2 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 9 |
GO:0031065 | positive regulation of histone deacetylation | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 2 | 9 |
GO:0044212 | transcription regulatory region DNA binding | 6.92e-03 | 1.00e+00 | 3.964 | 2 | 17 | 168 |
GO:0031274 | positive regulation of pseudopodium assembly | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 2 | 10 |
GO:0050872 | white fat cell differentiation | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 10 |
GO:0035413 | positive regulation of catenin import into nucleus | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 2 | 10 |
GO:0030877 | beta-catenin destruction complex | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 2 | 10 |
GO:0005515 | protein binding | 8.30e-03 | 1.00e+00 | 0.970 | 9 | 198 | 6024 |
GO:0051010 | microtubule plus-end binding | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0017166 | vinculin binding | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0031116 | positive regulation of microtubule polymerization | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0043923 | positive regulation by host of viral transcription | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 3 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 4 | 11 |
GO:0032886 | regulation of microtubule-based process | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 12 |
GO:0045295 | gamma-catenin binding | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 12 |
GO:0019079 | viral genome replication | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 2 | 12 |
GO:0035198 | miRNA binding | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 12 |
GO:0005737 | cytoplasm | 9.75e-03 | 1.00e+00 | 1.285 | 7 | 124 | 3767 |
GO:0071480 | cellular response to gamma radiation | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 13 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 13 |
GO:0044295 | axonal growth cone | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 13 |
GO:0043409 | negative regulation of MAPK cascade | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 13 |
GO:0035371 | microtubule plus-end | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 14 |
GO:0031011 | Ino80 complex | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 6 | 14 |
GO:0070542 | response to fatty acid | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 14 |
GO:0034614 | cellular response to reactive oxygen species | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 2 | 14 |
GO:0032993 | protein-DNA complex | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 2 | 14 |
GO:0001824 | blastocyst development | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 2 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 15 |
GO:0007026 | negative regulation of microtubule depolymerization | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0046716 | muscle cell cellular homeostasis | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0043274 | phospholipase binding | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0051276 | chromosome organization | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 2 | 16 |
GO:0003713 | transcription coactivator activity | 1.34e-02 | 1.00e+00 | 3.468 | 2 | 24 | 237 |
GO:0031122 | cytoplasmic microtubule organization | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 18 |
GO:0045773 | positive regulation of axon extension | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 3 | 18 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 1.40e-02 | 1.00e+00 | 2.492 | 3 | 39 | 699 |
GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 2 | 19 |
GO:0035257 | nuclear hormone receptor binding | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 1 | 20 |
GO:0001106 | RNA polymerase II transcription corepressor activity | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 2 | 21 |
GO:0032967 | positive regulation of collagen biosynthetic process | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 2 | 21 |
GO:0048041 | focal adhesion assembly | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 1 | 21 |
GO:0000123 | histone acetyltransferase complex | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 6 | 21 |
GO:0009954 | proximal/distal pattern formation | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 1 | 21 |
GO:0000281 | mitotic cytokinesis | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 2 | 21 |
GO:0003823 | antigen binding | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 2 | 22 |
GO:0043388 | positive regulation of DNA binding | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 24 |
GO:0045296 | cadherin binding | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 3 | 24 |
GO:0043425 | bHLH transcription factor binding | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 24 |
GO:0051059 | NF-kappaB binding | 1.89e-02 | 1.00e+00 | 5.713 | 1 | 3 | 25 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.93e-02 | 1.00e+00 | 2.318 | 3 | 41 | 789 |
GO:0035329 | hippo signaling | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 5 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 26 |
GO:0048754 | branching morphogenesis of an epithelial tube | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 27 |
GO:0034612 | response to tumor necrosis factor | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 27 |
GO:0005875 | microtubule associated complex | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 28 |
GO:0050714 | positive regulation of protein secretion | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 3 | 28 |
GO:0030162 | regulation of proteolysis | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 2 | 28 |
GO:0070491 | repressing transcription factor binding | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 2 | 28 |
GO:0070830 | tight junction assembly | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 28 |
GO:0005913 | cell-cell adherens junction | 2.19e-02 | 1.00e+00 | 5.499 | 1 | 3 | 29 |
GO:0030032 | lamellipodium assembly | 2.19e-02 | 1.00e+00 | 5.499 | 1 | 1 | 29 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 1 | 30 |
GO:0009953 | dorsal/ventral pattern formation | 2.34e-02 | 1.00e+00 | 5.402 | 1 | 2 | 31 |
GO:0007094 | mitotic spindle assembly checkpoint | 2.34e-02 | 1.00e+00 | 5.402 | 1 | 3 | 31 |
GO:0043491 | protein kinase B signaling | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 2 | 32 |
GO:0051287 | NAD binding | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 2 | 32 |
GO:0008283 | cell proliferation | 2.48e-02 | 1.00e+00 | 2.999 | 2 | 14 | 328 |
GO:0001756 | somitogenesis | 2.49e-02 | 1.00e+00 | 5.312 | 1 | 1 | 33 |
GO:0033077 | T cell differentiation in thymus | 2.49e-02 | 1.00e+00 | 5.312 | 1 | 1 | 33 |
GO:0071333 | cellular response to glucose stimulus | 2.49e-02 | 1.00e+00 | 5.312 | 1 | 1 | 33 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 36 |
GO:0034446 | substrate adhesion-dependent cell spreading | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 36 |
GO:0048538 | thymus development | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 36 |
GO:0030199 | collagen fibril organization | 2.79e-02 | 1.00e+00 | 5.147 | 1 | 2 | 37 |
GO:0008285 | negative regulation of cell proliferation | 2.84e-02 | 1.00e+00 | 2.893 | 2 | 10 | 353 |
GO:0005730 | nucleolus | 2.86e-02 | 1.00e+00 | 1.676 | 4 | 66 | 1641 |
GO:0031490 | chromatin DNA binding | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 2 | 38 |
GO:0032092 | positive regulation of protein binding | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 1 | 38 |
GO:0051781 | positive regulation of cell division | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 1 | 39 |
GO:0005881 | cytoplasmic microtubule | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 1 | 40 |
GO:0045785 | positive regulation of cell adhesion | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 2 | 40 |
GO:0046332 | SMAD binding | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 1 | 40 |
GO:0007519 | skeletal muscle tissue development | 3.01e-02 | 1.00e+00 | 5.035 | 1 | 2 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 3.08e-02 | 1.00e+00 | 4.999 | 1 | 2 | 41 |
GO:0007155 | cell adhesion | 3.08e-02 | 1.00e+00 | 2.829 | 2 | 5 | 369 |
GO:0031124 | mRNA 3'-end processing | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 2 | 42 |
GO:0004402 | histone acetyltransferase activity | 3.23e-02 | 1.00e+00 | 4.930 | 1 | 6 | 43 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 3.31e-02 | 1.00e+00 | 4.897 | 1 | 4 | 44 |
GO:0003712 | transcription cofactor activity | 3.31e-02 | 1.00e+00 | 4.897 | 1 | 8 | 44 |
GO:0045727 | positive regulation of translation | 3.31e-02 | 1.00e+00 | 4.897 | 1 | 2 | 44 |
GO:0043966 | histone H3 acetylation | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 5 | 45 |
GO:0006369 | termination of RNA polymerase II transcription | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 2 | 45 |
GO:0016328 | lateral plasma membrane | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 3 | 46 |
GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 3.53e-02 | 1.00e+00 | 4.802 | 1 | 2 | 47 |
GO:0007030 | Golgi organization | 3.68e-02 | 1.00e+00 | 4.742 | 1 | 3 | 49 |
GO:0035690 | cellular response to drug | 3.68e-02 | 1.00e+00 | 4.742 | 1 | 3 | 49 |
GO:0006986 | response to unfolded protein | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 4 | 50 |
GO:0045732 | positive regulation of protein catabolic process | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 1 | 50 |
GO:0060041 | retina development in camera-type eye | 3.82e-02 | 1.00e+00 | 4.684 | 1 | 2 | 51 |
GO:0017053 | transcriptional repressor complex | 3.82e-02 | 1.00e+00 | 4.684 | 1 | 2 | 51 |
GO:0051028 | mRNA transport | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 4 | 52 |
GO:0009611 | response to wounding | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 3.97e-02 | 1.00e+00 | 4.629 | 1 | 1 | 53 |
GO:0005518 | collagen binding | 4.04e-02 | 1.00e+00 | 4.602 | 1 | 2 | 54 |
GO:0051592 | response to calcium ion | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 1 | 55 |
GO:0002039 | p53 binding | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 4 | 55 |
GO:0001725 | stress fiber | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 4 | 55 |
GO:0071300 | cellular response to retinoic acid | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 1 | 55 |
GO:0044822 | poly(A) RNA binding | 4.14e-02 | 1.00e+00 | 1.897 | 3 | 50 | 1056 |
GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 2 | 56 |
GO:0043627 | response to estrogen | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 5 | 56 |
GO:0005643 | nuclear pore | 4.26e-02 | 1.00e+00 | 4.524 | 1 | 11 | 57 |
GO:0032481 | positive regulation of type I interferon production | 4.56e-02 | 1.00e+00 | 4.426 | 1 | 6 | 61 |
GO:0006406 | mRNA export from nucleus | 4.56e-02 | 1.00e+00 | 4.426 | 1 | 4 | 61 |
GO:0019903 | protein phosphatase binding | 4.63e-02 | 1.00e+00 | 4.402 | 1 | 2 | 62 |
GO:0004867 | serine-type endopeptidase inhibitor activity | 4.70e-02 | 1.00e+00 | 4.379 | 1 | 3 | 63 |
GO:0000776 | kinetochore | 4.70e-02 | 1.00e+00 | 4.379 | 1 | 5 | 63 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 4.70e-02 | 1.00e+00 | 4.379 | 1 | 4 | 63 |
GO:0006310 | DNA recombination | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 7 | 65 |
GO:0007409 | axonogenesis | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 2 | 65 |
GO:0010468 | regulation of gene expression | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 2 | 68 |
GO:0034329 | cell junction assembly | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 3 | 68 |
GO:0032587 | ruffle membrane | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 3 | 70 |
GO:0030324 | lung development | 5.36e-02 | 1.00e+00 | 4.187 | 1 | 1 | 72 |
GO:0000785 | chromatin | 5.43e-02 | 1.00e+00 | 4.167 | 1 | 6 | 73 |
GO:0002020 | protease binding | 5.50e-02 | 1.00e+00 | 4.147 | 1 | 6 | 74 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 5.50e-02 | 1.00e+00 | 4.147 | 1 | 4 | 74 |
GO:0060070 | canonical Wnt signaling pathway | 5.58e-02 | 1.00e+00 | 4.128 | 1 | 4 | 75 |
GO:0001889 | liver development | 5.72e-02 | 1.00e+00 | 4.090 | 1 | 3 | 77 |
GO:0001822 | kidney development | 5.79e-02 | 1.00e+00 | 4.071 | 1 | 3 | 78 |
GO:0007229 | integrin-mediated signaling pathway | 5.79e-02 | 1.00e+00 | 4.071 | 1 | 3 | 78 |
GO:0003677 | DNA binding | 5.93e-02 | 1.00e+00 | 1.691 | 3 | 49 | 1218 |
GO:0009653 | anatomical structure morphogenesis | 6.15e-02 | 1.00e+00 | 3.982 | 1 | 2 | 83 |
GO:0009952 | anterior/posterior pattern specification | 6.15e-02 | 1.00e+00 | 3.982 | 1 | 4 | 83 |
GO:0005923 | tight junction | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 2 | 86 |
GO:0009887 | organ morphogenesis | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 5 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 3 | 86 |
GO:0006936 | muscle contraction | 6.44e-02 | 1.00e+00 | 3.914 | 1 | 3 | 87 |
GO:0006915 | apoptotic process | 6.46e-02 | 1.00e+00 | 2.240 | 2 | 12 | 555 |
GO:0000187 | activation of MAPK activity | 6.66e-02 | 1.00e+00 | 3.865 | 1 | 3 | 90 |
GO:0007010 | cytoskeleton organization | 6.73e-02 | 1.00e+00 | 3.849 | 1 | 4 | 91 |
GO:0006928 | cellular component movement | 6.73e-02 | 1.00e+00 | 3.849 | 1 | 3 | 91 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 6.77e-02 | 1.00e+00 | 2.202 | 2 | 37 | 570 |
GO:0071456 | cellular response to hypoxia | 6.80e-02 | 1.00e+00 | 3.833 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 6.80e-02 | 1.00e+00 | 3.833 | 1 | 7 | 92 |
GO:0051082 | unfolded protein binding | 6.87e-02 | 1.00e+00 | 3.817 | 1 | 7 | 93 |
GO:0005178 | integrin binding | 7.09e-02 | 1.00e+00 | 3.772 | 1 | 4 | 96 |
GO:0008360 | regulation of cell shape | 7.58e-02 | 1.00e+00 | 3.670 | 1 | 4 | 103 |
GO:0001934 | positive regulation of protein phosphorylation | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 5 | 104 |
GO:0010951 | negative regulation of endopeptidase activity | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 6 | 104 |
GO:0005938 | cell cortex | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 5 | 104 |
GO:0006461 | protein complex assembly | 8.15e-02 | 1.00e+00 | 3.562 | 1 | 4 | 111 |
GO:0030529 | ribonucleoprotein complex | 8.22e-02 | 1.00e+00 | 3.549 | 1 | 5 | 112 |
GO:0006325 | chromatin organization | 8.64e-02 | 1.00e+00 | 3.474 | 1 | 12 | 118 |
GO:0007219 | Notch signaling pathway | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 5 | 120 |
GO:0010467 | gene expression | 8.95e-02 | 1.00e+00 | 1.971 | 2 | 45 | 669 |
GO:0007050 | cell cycle arrest | 9.06e-02 | 1.00e+00 | 3.402 | 1 | 5 | 124 |
GO:0030335 | positive regulation of cell migration | 9.27e-02 | 1.00e+00 | 3.368 | 1 | 5 | 127 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 9.34e-02 | 1.00e+00 | 3.357 | 1 | 11 | 128 |
GO:0016477 | cell migration | 9.34e-02 | 1.00e+00 | 3.357 | 1 | 4 | 128 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 9.62e-02 | 1.00e+00 | 3.312 | 1 | 4 | 132 |
GO:0000086 | G2/M transition of mitotic cell cycle | 9.90e-02 | 1.00e+00 | 3.269 | 1 | 4 | 136 |
GO:0007507 | heart development | 1.01e-01 | 1.00e+00 | 3.238 | 1 | 7 | 139 |
GO:0005788 | endoplasmic reticulum lumen | 1.05e-01 | 1.00e+00 | 3.177 | 1 | 5 | 145 |
GO:0008017 | microtubule binding | 1.07e-01 | 1.00e+00 | 3.157 | 1 | 2 | 147 |
GO:0005829 | cytosol | 1.07e-01 | 1.00e+00 | 1.071 | 4 | 86 | 2496 |
GO:0001666 | response to hypoxia | 1.08e-01 | 1.00e+00 | 3.137 | 1 | 7 | 149 |
GO:0008022 | protein C-terminus binding | 1.16e-01 | 1.00e+00 | 3.026 | 1 | 8 | 161 |
GO:0000398 | mRNA splicing, via spliceosome | 1.18e-01 | 1.00e+00 | 2.999 | 1 | 15 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 12 | 165 |
GO:0016607 | nuclear speck | 1.24e-01 | 1.00e+00 | 2.930 | 1 | 12 | 172 |
GO:0019904 | protein domain specific binding | 1.28e-01 | 1.00e+00 | 2.873 | 1 | 8 | 179 |
GO:0031625 | ubiquitin protein ligase binding | 1.28e-01 | 1.00e+00 | 2.881 | 1 | 5 | 178 |
GO:0003714 | transcription corepressor activity | 1.28e-01 | 1.00e+00 | 2.881 | 1 | 11 | 178 |
GO:0032403 | protein complex binding | 1.31e-01 | 1.00e+00 | 2.841 | 1 | 6 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.32e-01 | 1.00e+00 | 2.833 | 1 | 22 | 184 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.35e-01 | 1.00e+00 | 2.794 | 1 | 5 | 189 |
GO:0008380 | RNA splicing | 1.61e-01 | 1.00e+00 | 2.524 | 1 | 22 | 228 |
GO:0007399 | nervous system development | 1.63e-01 | 1.00e+00 | 2.505 | 1 | 6 | 231 |
GO:0008270 | zinc ion binding | 1.74e-01 | 1.00e+00 | 1.395 | 2 | 27 | 997 |
GO:0000166 | nucleotide binding | 1.81e-01 | 1.00e+00 | 2.340 | 1 | 13 | 259 |
GO:0006281 | DNA repair | 1.82e-01 | 1.00e+00 | 2.329 | 1 | 14 | 261 |
GO:0043065 | positive regulation of apoptotic process | 1.86e-01 | 1.00e+00 | 2.291 | 1 | 7 | 268 |
GO:0006954 | inflammatory response | 1.92e-01 | 1.00e+00 | 2.243 | 1 | 6 | 277 |
GO:0019899 | enzyme binding | 1.92e-01 | 1.00e+00 | 2.243 | 1 | 9 | 277 |
GO:0030198 | extracellular matrix organization | 1.96e-01 | 1.00e+00 | 2.212 | 1 | 6 | 283 |
GO:0005856 | cytoskeleton | 2.01e-01 | 1.00e+00 | 2.172 | 1 | 9 | 291 |
GO:0005813 | centrosome | 2.22e-01 | 1.00e+00 | 2.008 | 1 | 7 | 326 |
GO:0003682 | chromatin binding | 2.23e-01 | 1.00e+00 | 2.004 | 1 | 19 | 327 |
GO:0015031 | protein transport | 2.31e-01 | 1.00e+00 | 1.943 | 1 | 11 | 341 |
GO:0003723 | RNA binding | 2.32e-01 | 1.00e+00 | 1.939 | 1 | 18 | 342 |
GO:0043565 | sequence-specific DNA binding | 2.34e-01 | 1.00e+00 | 1.922 | 1 | 11 | 346 |
GO:0005925 | focal adhesion | 2.46e-01 | 1.00e+00 | 1.841 | 1 | 9 | 366 |
GO:0000278 | mitotic cell cycle | 2.61e-01 | 1.00e+00 | 1.746 | 1 | 15 | 391 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.74e-01 | 1.00e+00 | 1.667 | 1 | 24 | 413 |
GO:0055114 | oxidation-reduction process | 2.78e-01 | 1.00e+00 | 1.642 | 1 | 10 | 420 |
GO:0006468 | protein phosphorylation | 3.00e-01 | 1.00e+00 | 1.511 | 1 | 10 | 460 |
GO:0006351 | transcription, DNA-templated | 3.04e-01 | 1.00e+00 | 0.859 | 2 | 57 | 1446 |
GO:0048471 | perinuclear region of cytoplasm | 3.23e-01 | 1.00e+00 | 1.385 | 1 | 8 | 502 |
GO:0016032 | viral process | 3.40e-01 | 1.00e+00 | 1.296 | 1 | 26 | 534 |
GO:0005783 | endoplasmic reticulum | 3.51e-01 | 1.00e+00 | 1.238 | 1 | 13 | 556 |
GO:0042803 | protein homodimerization activity | 3.71e-01 | 1.00e+00 | 1.140 | 1 | 19 | 595 |
GO:0045087 | innate immune response | 3.71e-01 | 1.00e+00 | 1.137 | 1 | 15 | 596 |
GO:0007165 | signal transduction | 5.11e-01 | 1.00e+00 | 0.532 | 1 | 13 | 907 |
GO:0005615 | extracellular space | 5.30e-01 | 1.00e+00 | 0.454 | 1 | 20 | 957 |
GO:0070062 | extracellular vesicular exosome | 5.68e-01 | 1.00e+00 | 0.128 | 2 | 57 | 2400 |
GO:0005886 | plasma membrane | 6.12e-01 | 1.00e+00 | 0.022 | 2 | 49 | 2582 |
GO:0016020 | membrane | 7.44e-01 | 1.00e+00 | -0.358 | 1 | 46 | 1681 |