int-snw-79602

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.811	3.02e-15	6.46e-04	4.16e-03

chia-screen-data-Fav-int-snw-79602 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
LARS	51520	14	-2.574	3.157	105	Yes	Yes
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
MED19	219541	30	-2.657	3.449	115	Yes	-
EIF2S2	8894	9	-2.999	2.968	81	Yes	Yes
TMED10	10972	3	-1.992	3.104	106	-	-
LUC7L3	51747	33	-3.523	3.449	18	Yes	-
PHB	5245	15	-2.743	3.004	127	Yes	Yes
[ ADIPOR2 ]	79602	1	-1.455	2.811	12	-	-
ETF1	2107	3	-2.829	2.959	71	Yes	Yes
SCD	6319	1	-1.715	2.811	69	-	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
IPO4	79711	2	-1.739	2.842	177	-	-

Interactions (15)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
SCD	6319	ADIPOR2	79602	pp	--	int.I2D: BioGrid_Yeast
SCD	6319	TMED10	10972	pp	--	int.I2D: BioGrid_Yeast, MINT_Yeast, Tarassov_PCA, IntAct_Yeast
IPO4	79711	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
PSMD2	5708	LARS	51520	pp	--	int.I2D: BioGrid_Yeast
PHB	5245	TMED10	10972	pp	--	int.I2D: YeastLow
TMED10	10972	IPO4	79711	pp	--	int.I2D: IntAct_Yeast, YeastLow
ETF1	2107	IPO4	79711	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
SRSF3	6428	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
ETF1	2107	EIF2S2	8894	pp	--	int.I2D: BioGrid_Yeast, YeastLow
SCD	6319	IPO4	79711	pp	--	int.I2D: IntAct_Yeast
PSMD2	5708	SCD	6319	pp	--	int.I2D: BioGrid_Yeast
LUC7L3	51747	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
PSMD2	5708	IPO4	79711	pp	--	int.I2D: BioGrid_Yeast
PSMD2	5708	TMED10	10972	pp	--	int.I2D: IntAct_Yeast

Related GO terms (177)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010467	gene expression	1.99e-04	1.00e+00	3.052	5	45	669
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.01e-04	1.00e+00	10.116	1	1	1
GO:0048199	vesicle targeting, to, from or within Golgi	9.01e-04	1.00e+00	10.116	1	1	1
GO:0035964	COPI-coated vesicle budding	9.01e-04	1.00e+00	10.116	1	1	1
GO:0008079	translation termination factor activity	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.01e-04	1.00e+00	10.116	1	1	1
GO:1902003	regulation of beta-amyloid formation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.01e-04	1.00e+00	10.116	1	1	1
GO:0044822	poly(A) RNA binding	1.63e-03	1.00e+00	2.393	5	50	1056
GO:0070765	gamma-secretase complex	1.80e-03	1.00e+00	9.116	1	1	2
GO:0006429	leucyl-tRNA aminoacylation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0002176	male germ cell proliferation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009786	regulation of asymmetric cell division	1.80e-03	1.00e+00	9.116	1	1	2
GO:0004823	leucine-tRNA ligase activity	1.80e-03	1.00e+00	9.116	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	2.70e-03	1.00e+00	8.531	1	1	3
GO:0016149	translation release factor activity, codon specific	2.70e-03	1.00e+00	8.531	1	1	3
GO:0004768	stearoyl-CoA 9-desaturase activity	2.70e-03	1.00e+00	8.531	1	1	3
GO:0060913	cardiac cell fate determination	2.70e-03	1.00e+00	8.531	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.70e-03	1.00e+00	8.531	1	1	3
GO:0055100	adiponectin binding	2.70e-03	1.00e+00	8.531	1	1	3
GO:0003723	RNA binding	3.17e-03	1.00e+00	3.283	3	18	342
GO:0035459	cargo loading into vesicle	3.60e-03	1.00e+00	8.116	1	1	4
GO:0030137	COPI-coated vesicle	3.60e-03	1.00e+00	8.116	1	1	4
GO:0003747	translation release factor activity	3.60e-03	1.00e+00	8.116	1	2	4
GO:0030308	negative regulation of cell growth	4.26e-03	1.00e+00	4.334	2	6	110
GO:0001714	endodermal cell fate specification	4.50e-03	1.00e+00	7.794	1	1	5
GO:0043279	response to alkaloid	4.50e-03	1.00e+00	7.794	1	2	5
GO:0006449	regulation of translational termination	4.50e-03	1.00e+00	7.794	1	1	5
GO:0050847	progesterone receptor signaling pathway	5.40e-03	1.00e+00	7.531	1	2	6
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.40e-03	1.00e+00	7.531	1	1	6
GO:0033211	adiponectin-activated signaling pathway	5.40e-03	1.00e+00	7.531	1	1	6
GO:0006366	transcription from RNA polymerase II promoter	5.60e-03	1.00e+00	2.990	3	30	419
GO:0071354	cellular response to interleukin-6	6.29e-03	1.00e+00	7.308	1	2	7
GO:0002161	aminoacyl-tRNA editing activity	6.29e-03	1.00e+00	7.308	1	2	7
GO:0042981	regulation of apoptotic process	7.77e-03	1.00e+00	3.887	2	4	150
GO:0006450	regulation of translational fidelity	8.09e-03	1.00e+00	6.946	1	2	9
GO:0010944	negative regulation of transcription by competitive promoter binding	8.09e-03	1.00e+00	6.946	1	1	9
GO:0035413	positive regulation of catenin import into nucleus	8.98e-03	1.00e+00	6.794	1	2	10
GO:0045055	regulated secretory pathway	8.98e-03	1.00e+00	6.794	1	1	10
GO:0042589	zymogen granule membrane	8.98e-03	1.00e+00	6.794	1	1	10
GO:0044212	transcription regulatory region DNA binding	9.67e-03	1.00e+00	3.723	2	17	168
GO:0019395	fatty acid oxidation	9.87e-03	1.00e+00	6.656	1	2	11
GO:0060391	positive regulation of SMAD protein import into nucleus	9.87e-03	1.00e+00	6.656	1	4	11
GO:0006886	intracellular protein transport	1.00e-02	1.00e+00	3.698	2	4	171
GO:0016607	nuclear speck	1.01e-02	1.00e+00	3.689	2	12	172
GO:0030667	secretory granule membrane	1.08e-02	1.00e+00	6.531	1	2	12
GO:0030140	trans-Golgi network transport vesicle	1.08e-02	1.00e+00	6.531	1	1	12
GO:0005838	proteasome regulatory particle	1.08e-02	1.00e+00	6.531	1	1	12
GO:0035198	miRNA binding	1.08e-02	1.00e+00	6.531	1	1	12
GO:0060766	negative regulation of androgen receptor signaling pathway	1.17e-02	1.00e+00	6.415	1	3	13
GO:0048205	COPI coating of Golgi vesicle	1.17e-02	1.00e+00	6.415	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.17e-02	1.00e+00	6.415	1	2	13
GO:0030234	enzyme regulator activity	1.17e-02	1.00e+00	6.415	1	2	13
GO:0006479	protein methylation	1.26e-02	1.00e+00	6.308	1	2	14
GO:0005685	U1 snRNP	1.26e-02	1.00e+00	6.308	1	1	14
GO:0005654	nucleoplasm	1.30e-02	1.00e+00	2.036	4	64	1082
GO:0048208	COPII vesicle coating	1.34e-02	1.00e+00	6.209	1	1	15
GO:0001824	blastocyst development	1.34e-02	1.00e+00	6.209	1	2	15
GO:0006376	mRNA splice site selection	1.34e-02	1.00e+00	6.209	1	1	15
GO:0042562	hormone binding	1.43e-02	1.00e+00	6.116	1	1	16
GO:0043274	phospholipase binding	1.43e-02	1.00e+00	6.116	1	1	16
GO:0042176	regulation of protein catabolic process	1.43e-02	1.00e+00	6.116	1	2	16
GO:0006336	DNA replication-independent nucleosome assembly	1.43e-02	1.00e+00	6.116	1	2	16
GO:0022624	proteasome accessory complex	1.52e-02	1.00e+00	6.028	1	1	17
GO:0006335	DNA replication-dependent nucleosome assembly	1.52e-02	1.00e+00	6.028	1	2	17
GO:0009755	hormone-mediated signaling pathway	1.61e-02	1.00e+00	5.946	1	1	18
GO:0016071	mRNA metabolic process	1.66e-02	1.00e+00	3.315	2	8	223
GO:0008380	RNA splicing	1.73e-02	1.00e+00	3.283	2	22	228
GO:0006412	translation	1.76e-02	1.00e+00	3.270	2	8	230
GO:0016575	histone deacetylation	1.88e-02	1.00e+00	5.723	1	3	21
GO:0016070	RNA metabolic process	2.01e-02	1.00e+00	3.167	2	8	247
GO:0008135	translation factor activity, nucleic acid binding	2.14e-02	1.00e+00	5.531	1	3	24
GO:0046326	positive regulation of glucose import	2.14e-02	1.00e+00	5.531	1	1	24
GO:0008536	Ran GTPase binding	2.23e-02	1.00e+00	5.472	1	2	25
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.23e-02	1.00e+00	5.472	1	1	25
GO:0043022	ribosome binding	2.41e-02	1.00e+00	5.361	1	1	27
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	2.41e-02	1.00e+00	5.361	1	1	27
GO:0071897	DNA biosynthetic process	2.50e-02	1.00e+00	5.308	1	1	28
GO:0030658	transport vesicle membrane	2.85e-02	1.00e+00	5.116	1	1	32
GO:0006633	fatty acid biosynthetic process	2.85e-02	1.00e+00	5.116	1	1	32
GO:0019905	syntaxin binding	2.94e-02	1.00e+00	5.071	1	2	33
GO:0001104	RNA polymerase II transcription cofactor activity	2.94e-02	1.00e+00	5.071	1	8	33
GO:0005801	cis-Golgi network	2.94e-02	1.00e+00	5.071	1	1	33
GO:0016592	mediator complex	3.11e-02	1.00e+00	4.986	1	10	35
GO:0051259	protein oligomerization	3.46e-02	1.00e+00	4.830	1	2	39
GO:0035019	somatic stem cell maintenance	3.55e-02	1.00e+00	4.794	1	6	40
GO:0006418	tRNA aminoacylation for protein translation	3.72e-02	1.00e+00	4.723	1	3	42
GO:0031124	mRNA 3'-end processing	3.72e-02	1.00e+00	4.723	1	2	42
GO:0006369	termination of RNA polymerase II transcription	3.98e-02	1.00e+00	4.624	1	2	45
GO:0005515	protein binding	4.29e-02	1.00e+00	0.729	9	198	6024
GO:0007030	Golgi organization	4.33e-02	1.00e+00	4.501	1	3	49
GO:0003743	translation initiation factor activity	4.33e-02	1.00e+00	4.501	1	7	49
GO:0006521	regulation of cellular amino acid metabolic process	4.42e-02	1.00e+00	4.472	1	1	50
GO:0009611	response to wounding	4.59e-02	1.00e+00	4.415	1	5	52
GO:0006888	ER to Golgi vesicle-mediated transport	4.68e-02	1.00e+00	4.388	1	1	53
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	4.93e-02	1.00e+00	4.308	1	2	56
GO:0005643	nuclear pore	5.02e-02	1.00e+00	4.283	1	11	57
GO:0000502	proteasome complex	5.11e-02	1.00e+00	4.258	1	3	58
GO:0006406	mRNA export from nucleus	5.36e-02	1.00e+00	4.185	1	4	61
GO:0016020	membrane	5.55e-02	1.00e+00	1.401	4	46	1681
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.62e-02	1.00e+00	4.116	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.71e-02	1.00e+00	4.093	1	2	65
GO:0005829	cytosol	5.88e-02	1.00e+00	1.152	5	86	2496
GO:0010468	regulation of gene expression	5.96e-02	1.00e+00	4.028	1	2	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.13e-02	1.00e+00	3.986	1	2	70
GO:0007584	response to nutrient	6.22e-02	1.00e+00	3.966	1	3	71
GO:0042826	histone deacetylase binding	6.30e-02	1.00e+00	3.946	1	4	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.30e-02	1.00e+00	3.946	1	1	72
GO:0003729	mRNA binding	6.30e-02	1.00e+00	3.946	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	6.47e-02	1.00e+00	3.906	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.47e-02	1.00e+00	3.906	1	2	74
GO:0008584	male gonad development	6.56e-02	1.00e+00	3.887	1	3	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.56e-02	1.00e+00	3.887	1	1	75
GO:0044267	cellular protein metabolic process	6.62e-02	1.00e+00	2.227	2	20	474
GO:0007565	female pregnancy	6.81e-02	1.00e+00	3.830	1	2	78
GO:0001822	kidney development	6.81e-02	1.00e+00	3.830	1	3	78
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.89e-02	1.00e+00	3.812	1	2	79
GO:0009653	anatomical structure morphogenesis	7.23e-02	1.00e+00	3.741	1	2	83
GO:0006415	translational termination	7.57e-02	1.00e+00	3.673	1	2	87
GO:0042470	melanosome	7.90e-02	1.00e+00	3.608	1	2	91
GO:0001649	osteoblast differentiation	7.99e-02	1.00e+00	3.592	1	5	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.99e-02	1.00e+00	3.592	1	1	92
GO:0005783	endoplasmic reticulum	8.74e-02	1.00e+00	1.997	2	13	556
GO:0005506	iron ion binding	9.07e-02	1.00e+00	3.401	1	3	105
GO:0005789	endoplasmic reticulum membrane	9.12e-02	1.00e+00	1.961	2	9	570
GO:0005737	cytoplasm	9.60e-02	1.00e+00	0.821	6	124	3767
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	9.81e-02	1.00e+00	3.283	1	4	114
GO:0000209	protein polyubiquitination	9.97e-02	1.00e+00	3.258	1	3	116
GO:0000790	nuclear chromatin	1.10e-01	1.00e+00	3.104	1	6	129
GO:0006413	translational initiation	1.12e-01	1.00e+00	3.082	1	7	131
GO:0007507	heart development	1.18e-01	1.00e+00	2.997	1	7	139
GO:0000082	G1/S transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	3	149
GO:0000398	mRNA splicing, via spliceosome	1.38e-01	1.00e+00	2.758	1	15	164
GO:0034641	cellular nitrogen compound metabolic process	1.44e-01	1.00e+00	2.698	1	2	171
GO:0005667	transcription factor complex	1.47e-01	1.00e+00	2.664	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.49e-01	1.00e+00	2.640	1	5	178
GO:0032403	protein complex binding	1.53e-01	1.00e+00	2.600	1	6	183
GO:0004872	receptor activity	1.58e-01	1.00e+00	2.553	1	8	189
GO:0001701	in utero embryonic development	1.67e-01	1.00e+00	2.465	1	8	201
GO:0008134	transcription factor binding	1.98e-01	1.00e+00	2.197	1	18	242
GO:0000166	nucleotide binding	2.10e-01	1.00e+00	2.099	1	13	259
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.14e-01	1.00e+00	2.071	1	23	264
GO:0005743	mitochondrial inner membrane	2.23e-01	1.00e+00	2.002	1	6	277
GO:0019899	enzyme binding	2.23e-01	1.00e+00	2.002	1	9	277
GO:0006355	regulation of transcription, DNA-templated	2.25e-01	1.00e+00	1.154	2	43	997
GO:0043234	protein complex	2.36e-01	1.00e+00	1.911	1	11	295
GO:0016021	integral component of membrane	2.61e-01	1.00e+00	0.748	3	17	1982
GO:0015031	protein transport	2.67e-01	1.00e+00	1.702	1	11	341
GO:0043565	sequence-specific DNA binding	2.71e-01	1.00e+00	1.681	1	11	346
GO:0008285	negative regulation of cell proliferation	2.75e-01	1.00e+00	1.652	1	10	353
GO:0000139	Golgi membrane	2.81e-01	1.00e+00	1.620	1	7	361
GO:0005925	focal adhesion	2.84e-01	1.00e+00	1.600	1	9	366
GO:0046982	protein heterodimerization activity	2.93e-01	1.00e+00	1.546	1	8	380
GO:0000278	mitotic cell cycle	3.01e-01	1.00e+00	1.505	1	15	391
GO:0003677	DNA binding	3.02e-01	1.00e+00	0.865	2	49	1218
GO:0045892	negative regulation of transcription, DNA-templated	3.15e-01	1.00e+00	1.426	1	24	413
GO:0055114	oxidation-reduction process	3.19e-01	1.00e+00	1.401	1	10	420
GO:0043066	negative regulation of apoptotic process	3.22e-01	1.00e+00	1.388	1	16	424
GO:0045893	positive regulation of transcription, DNA-templated	3.55e-01	1.00e+00	1.215	1	24	478
GO:0042802	identical protein binding	3.58e-01	1.00e+00	1.197	1	19	484
GO:0070062	extracellular vesicular exosome	3.71e-01	1.00e+00	0.472	3	57	2400
GO:0016032	viral process	3.88e-01	1.00e+00	1.055	1	26	534
GO:0005634	nucleus	3.95e-01	1.00e+00	0.283	5	159	4559
GO:0006915	apoptotic process	4.00e-01	1.00e+00	0.999	1	12	555
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.08e-01	1.00e+00	0.961	1	37	570
GO:0005886	plasma membrane	4.19e-01	1.00e+00	0.366	3	49	2582
GO:0005794	Golgi apparatus	4.30e-01	1.00e+00	0.863	1	9	610
GO:0003700	sequence-specific DNA binding transcription factor activity	4.76e-01	1.00e+00	0.666	1	39	699
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.19e-01	1.00e+00	0.492	1	41	789
GO:0005887	integral component of plasma membrane	5.62e-01	1.00e+00	0.321	1	10	888
GO:0007165	signal transduction	5.70e-01	1.00e+00	0.291	1	13	907
GO:0005739	mitochondrion	6.06e-01	1.00e+00	0.153	1	23	998
GO:0044281	small molecule metabolic process	6.80e-01	1.00e+00	-0.126	1	20	1211
GO:0005524	ATP binding	7.07e-01	1.00e+00	-0.226	1	31	1298
GO:0046872	metal ion binding	7.09e-01	1.00e+00	-0.236	1	29	1307
GO:0005730	nucleolus	7.92e-01	1.00e+00	-0.565	1	66	1641

chia-Fav

int-snw-79602

Statistics

Genes (13)

Interactions (15)

Related GO terms (177)