int-snw-54993

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.834	1.69e-15	4.88e-04	3.41e-03

chia-screen-data-Fav-int-snw-54993 subnetwork

Genes (11)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
ZFP64	55734	3	-3.174	2.908	14	Yes	Yes
ZNF513	130557	2	-2.256	2.905	7	Yes	-
NKD2	85409	1	-1.284	2.834	52	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
FUS	2521	2	-1.980	3.004	136	-	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
[ ZSCAN2 ]	54993	1	-1.165	2.834	3	-	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NKD2	85409	ZNF513	130557	pp	--	int.I2D: BioGrid_Mouse
ZSCAN2	54993	ZNF513	130557	pp	--	int.I2D: BioGrid_Mouse
FUS	2521	NKD2	85409	pp	--	int.Intact: MI:0915(physical association)
ZSCAN2	54993	NKD2	85409	pp	--	int.I2D: BioGrid_Mouse
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
ZFP64	55734	ZNF513	130557	pp	--	int.I2D: BioGrid; int.Ravasi: -
POU5F1	5460	ZNF513	130557	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse

Related GO terms (118)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006355	regulation of transcription, DNA-templated	1.91e-06	2.75e-02	3.203	7	43	997
GO:0003677	DNA binding	7.34e-06	1.06e-01	2.914	7	49	1218
GO:0005654	nucleoplasm	5.85e-05	8.43e-01	2.862	6	64	1082
GO:0006366	transcription from RNA polymerase II promoter	1.97e-04	1.00e+00	3.646	4	30	419
GO:0000398	mRNA splicing, via spliceosome	2.23e-04	1.00e+00	4.584	3	15	164
GO:0044212	transcription regulatory region DNA binding	2.39e-04	1.00e+00	4.549	3	17	168
GO:0008380	RNA splicing	5.86e-04	1.00e+00	4.109	3	22	228
GO:0060795	cell fate commitment involved in formation of primary germ layer	7.63e-04	1.00e+00	10.357	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	7.63e-04	1.00e+00	10.357	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	7.63e-04	1.00e+00	10.357	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	7.63e-04	1.00e+00	10.357	1	1	1
GO:0005634	nucleus	8.85e-04	1.00e+00	1.372	9	159	4559
GO:0010467	gene expression	1.17e-03	1.00e+00	2.971	4	45	669
GO:0019046	release from viral latency	1.52e-03	1.00e+00	9.357	1	2	2
GO:0009786	regulation of asymmetric cell division	1.52e-03	1.00e+00	9.357	1	1	2
GO:0048210	Golgi vesicle fusion to target membrane	1.52e-03	1.00e+00	9.357	1	1	2
GO:0060242	contact inhibition	1.52e-03	1.00e+00	9.357	1	1	2
GO:0003723	RNA binding	1.89e-03	1.00e+00	3.524	3	18	342
GO:0060913	cardiac cell fate determination	2.29e-03	1.00e+00	8.772	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.29e-03	1.00e+00	8.772	1	1	3
GO:0070461	SAGA-type complex	3.81e-03	1.00e+00	8.035	1	2	5
GO:0001714	endodermal cell fate specification	3.81e-03	1.00e+00	8.035	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	3.81e-03	1.00e+00	8.035	1	2	5
GO:0010954	positive regulation of protein processing	3.81e-03	1.00e+00	8.035	1	1	5
GO:0070937	CRD-mediated mRNA stability complex	4.57e-03	1.00e+00	7.772	1	3	6
GO:0070688	MLL5-L complex	6.09e-03	1.00e+00	7.357	1	1	8
GO:0043254	regulation of protein complex assembly	6.09e-03	1.00e+00	7.357	1	1	8
GO:0044822	poly(A) RNA binding	6.21e-03	1.00e+00	2.312	4	50	1056
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	6.85e-03	1.00e+00	7.187	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	6.85e-03	1.00e+00	7.187	1	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	6.85e-03	1.00e+00	7.187	1	5	9
GO:0048188	Set1C/COMPASS complex	6.85e-03	1.00e+00	7.187	1	4	9
GO:0035413	positive regulation of catenin import into nucleus	7.60e-03	1.00e+00	7.035	1	2	10
GO:0031625	ubiquitin protein ligase binding	7.74e-03	1.00e+00	3.881	2	5	178
GO:0060391	positive regulation of SMAD protein import into nucleus	8.36e-03	1.00e+00	6.897	1	4	11
GO:0035198	miRNA binding	9.12e-03	1.00e+00	6.772	1	1	12
GO:0071480	cellular response to gamma radiation	9.87e-03	1.00e+00	6.656	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	9.87e-03	1.00e+00	6.656	1	2	13
GO:0031011	Ino80 complex	1.06e-02	1.00e+00	6.549	1	6	14
GO:0043981	histone H4-K5 acetylation	1.14e-02	1.00e+00	6.450	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	1.14e-02	1.00e+00	6.450	1	3	15
GO:0001824	blastocyst development	1.14e-02	1.00e+00	6.450	1	2	15
GO:0043982	histone H4-K8 acetylation	1.14e-02	1.00e+00	6.450	1	5	15
GO:0043274	phospholipase binding	1.21e-02	1.00e+00	6.357	1	1	16
GO:0003713	transcription coactivator activity	1.34e-02	1.00e+00	3.468	2	24	237
GO:0003700	sequence-specific DNA binding transcription factor activity	1.40e-02	1.00e+00	2.492	3	39	699
GO:0072661	protein targeting to plasma membrane	1.44e-02	1.00e+00	6.109	1	1	19
GO:0043984	histone H4-K16 acetylation	1.44e-02	1.00e+00	6.109	1	5	19
GO:0000123	histone acetyltransferase complex	1.59e-02	1.00e+00	5.964	1	6	21
GO:0000166	nucleotide binding	1.59e-02	1.00e+00	3.340	2	13	259
GO:0036464	cytoplasmic ribonucleoprotein granule	1.67e-02	1.00e+00	5.897	1	2	22
GO:0090004	positive regulation of establishment of protein localization to plasma membrane	1.67e-02	1.00e+00	5.897	1	1	22
GO:0045787	positive regulation of cell cycle	1.67e-02	1.00e+00	5.897	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.67e-02	1.00e+00	5.897	1	4	22
GO:0071944	cell periphery	1.74e-02	1.00e+00	5.833	1	1	23
GO:0019838	growth factor binding	1.89e-02	1.00e+00	5.713	1	1	25
GO:0035329	hippo signaling	1.97e-02	1.00e+00	5.656	1	5	26
GO:0071339	MLL1 complex	2.04e-02	1.00e+00	5.602	1	6	27
GO:1903507	negative regulation of nucleic acid-templated transcription	2.41e-02	1.00e+00	5.357	1	2	32
GO:0035019	somatic stem cell maintenance	3.01e-02	1.00e+00	5.035	1	6	40
GO:0050896	response to stimulus	3.01e-02	1.00e+00	5.035	1	2	40
GO:0031124	mRNA 3'-end processing	3.16e-02	1.00e+00	4.964	1	2	42
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.31e-02	1.00e+00	4.897	1	3	44
GO:0006369	termination of RNA polymerase II transcription	3.38e-02	1.00e+00	4.865	1	2	45
GO:0016328	lateral plasma membrane	3.45e-02	1.00e+00	4.833	1	3	46
GO:0060041	retina development in camera-type eye	3.82e-02	1.00e+00	4.684	1	2	51
GO:0005515	protein binding	3.84e-02	1.00e+00	0.800	8	198	6024
GO:0009611	response to wounding	3.90e-02	1.00e+00	4.656	1	5	52
GO:0006396	RNA processing	4.41e-02	1.00e+00	4.474	1	5	59
GO:0006406	mRNA export from nucleus	4.56e-02	1.00e+00	4.426	1	4	61
GO:0006887	exocytosis	4.78e-02	1.00e+00	4.357	1	2	64
GO:0006310	DNA recombination	4.85e-02	1.00e+00	4.334	1	7	65
GO:0042802	identical protein binding	5.06e-02	1.00e+00	2.438	2	19	484
GO:0010468	regulation of gene expression	5.07e-02	1.00e+00	4.269	1	2	68
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	5.50e-02	1.00e+00	4.147	1	4	74
GO:0002020	protease binding	5.50e-02	1.00e+00	4.147	1	6	74
GO:0071013	catalytic step 2 spliceosome	5.79e-02	1.00e+00	4.071	1	7	78
GO:0009653	anatomical structure morphogenesis	6.15e-02	1.00e+00	3.982	1	2	83
GO:0090090	negative regulation of canonical Wnt signaling pathway	6.37e-02	1.00e+00	3.930	1	8	86
GO:0050821	protein stabilization	6.51e-02	1.00e+00	3.897	1	3	88
GO:0001649	osteoblast differentiation	6.80e-02	1.00e+00	3.833	1	5	92
GO:0046872	metal ion binding	7.06e-02	1.00e+00	1.590	3	29	1307
GO:0031410	cytoplasmic vesicle	7.58e-02	1.00e+00	3.670	1	4	103
GO:0016023	cytoplasmic membrane-bounded vesicle	7.73e-02	1.00e+00	3.642	1	8	105
GO:0030529	ribonucleoprotein complex	8.22e-02	1.00e+00	3.549	1	5	112
GO:0006325	chromatin organization	8.64e-02	1.00e+00	3.474	1	12	118
GO:0006351	transcription, DNA-templated	9.00e-02	1.00e+00	1.444	3	57	1446
GO:0016323	basolateral plasma membrane	9.83e-02	1.00e+00	3.280	1	3	135
GO:0016055	Wnt signaling pathway	1.00e-01	1.00e+00	3.248	1	4	138
GO:0010628	positive regulation of gene expression	1.06e-01	1.00e+00	3.167	1	7	146
GO:0006974	cellular response to DNA damage stimulus	1.09e-01	1.00e+00	3.118	1	7	151
GO:0007601	visual perception	1.13e-01	1.00e+00	3.062	1	5	157
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.19e-01	1.00e+00	1.733	2	41	789
GO:0005730	nucleolus	1.21e-01	1.00e+00	1.261	3	66	1641
GO:0016607	nuclear speck	1.24e-01	1.00e+00	2.930	1	12	172
GO:0007049	cell cycle	1.25e-01	1.00e+00	2.914	1	6	174
GO:0005667	transcription factor complex	1.26e-01	1.00e+00	2.905	1	17	175
GO:0003714	transcription corepressor activity	1.28e-01	1.00e+00	2.881	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.32e-01	1.00e+00	2.833	1	22	184
GO:0005737	cytoplasm	1.33e-01	1.00e+00	0.799	5	124	3767
GO:0008134	transcription factor binding	1.70e-01	1.00e+00	2.438	1	18	242
GO:0043025	neuronal cell body	1.72e-01	1.00e+00	2.420	1	9	245
GO:0006281	DNA repair	1.82e-01	1.00e+00	2.329	1	14	261
GO:0007283	spermatogenesis	1.83e-01	1.00e+00	2.323	1	3	262
GO:0006954	inflammatory response	1.92e-01	1.00e+00	2.243	1	6	277
GO:0030154	cell differentiation	2.07e-01	1.00e+00	2.123	1	5	301
GO:0007275	multicellular organismal development	2.16e-01	1.00e+00	2.053	1	7	316
GO:0003682	chromatin binding	2.23e-01	1.00e+00	2.004	1	19	327
GO:0008283	cell proliferation	2.24e-01	1.00e+00	1.999	1	14	328
GO:0043565	sequence-specific DNA binding	2.34e-01	1.00e+00	1.922	1	11	346
GO:0009986	cell surface	2.67e-01	1.00e+00	1.706	1	9	402
GO:0005509	calcium ion binding	3.38e-01	1.00e+00	1.304	1	11	531
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.58e-01	1.00e+00	1.202	1	37	570
GO:0016020	membrane	3.73e-01	1.00e+00	0.642	2	46	1681
GO:0008270	zinc ion binding	5.45e-01	1.00e+00	0.395	1	27	997
GO:0005739	mitochondrion	5.46e-01	1.00e+00	0.394	1	23	998
GO:0005829	cytosol	5.92e-01	1.00e+00	0.071	2	86	2496
GO:0005524	ATP binding	6.46e-01	1.00e+00	0.015	1	31	1298

chia-Fav

int-snw-54993

Statistics

Genes (11)

Interactions (11)

Related GO terms (118)