Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
chia-screen-data-Fav | 3.119 | 9.89e-19 | 1.04e-05 | 2.23e-04 |
Gene Symbol | Entrez Gene ID | Frequency | chia-screen-data-Fav gene score | Best subnetwork score | Degree | Chia-Hits Primary | Chia-Hits Secondary |
---|---|---|---|---|---|---|---|
EP300 | 2033 | 22 | -2.274 | 3.120 | 415 | Yes | Yes |
PSMD2 | 5708 | 47 | -4.172 | 3.157 | 386 | Yes | Yes |
TCP1 | 6950 | 10 | -2.383 | 3.119 | 241 | Yes | - |
CDC42 | 998 | 9 | -2.199 | 3.119 | 265 | Yes | Yes |
YAP1 | 10413 | 94 | -4.256 | 3.538 | 53 | Yes | - |
[ NAP1L4 ] | 4676 | 4 | -1.947 | 3.119 | 187 | - | - |
HNRNPU | 3192 | 76 | -2.869 | 3.538 | 139 | Yes | - |
POU5F1 | 5460 | 133 | -5.148 | 3.538 | 179 | Yes | Yes |
DDIT3 | 1649 | 60 | -2.825 | 3.504 | 343 | Yes | Yes |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
EP300 | 2033 | HNRNPU | 3192 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo |
DDIT3 | 1649 | TCP1 | 6950 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HNRNPU | 3192 | YAP1 | 10413 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
PSMD2 | 5708 | TCP1 | 6950 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow |
DDIT3 | 1649 | NAP1L4 | 4676 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HNRNPU | 3192 | POU5F1 | 5460 | pp | -- | int.I2D: BioGrid_Mouse, IntAct_Mouse |
EP300 | 2033 | YAP1 | 10413 | pp | -- | int.I2D: BioGrid |
CDC42 | 998 | NAP1L4 | 4676 | pp | -- | int.I2D: BioGrid_Yeast |
NAP1L4 | 4676 | TCP1 | 6950 | pp | -- | int.I2D: YeastLow |
EP300 | 2033 | NAP1L4 | 4676 | pp | -- | int.I2D: BioGrid, HPRD; int.Ravasi: -; int.HPRD: in vitro, in vivo |
DDIT3 | 1649 | HNRNPU | 3192 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
DDIT3 | 1649 | EP300 | 2033 | pp | -- | int.Intact: MI:0915(physical association) |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0005654 | nucleoplasm | 1.21e-05 | 1.75e-01 | 3.152 | 6 | 64 | 1082 |
GO:0042789 | mRNA transcription from RNA polymerase II promoter | 2.69e-05 | 3.88e-01 | 7.946 | 2 | 2 | 13 |
GO:0042176 | regulation of protein catabolic process | 4.13e-05 | 5.96e-01 | 7.646 | 2 | 2 | 16 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 7.94e-05 | 1.00e+00 | 7.187 | 2 | 2 | 22 |
GO:0044212 | transcription regulatory region DNA binding | 1.24e-04 | 1.00e+00 | 4.839 | 3 | 17 | 168 |
GO:0043525 | positive regulation of neuron apoptotic process | 3.53e-04 | 1.00e+00 | 6.123 | 2 | 4 | 46 |
GO:0008134 | transcription factor binding | 3.64e-04 | 1.00e+00 | 4.312 | 3 | 18 | 242 |
GO:0005515 | protein binding | 3.85e-04 | 1.00e+00 | 1.260 | 9 | 198 | 6024 |
GO:1901985 | positive regulation of protein acetylation | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:2000016 | negative regulation of determination of dorsal identity | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0043969 | histone H2B acetylation | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0090308 | regulation of methylation-dependent chromatin silencing | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0090081 | regulation of heart induction by regulation of canonical Wnt signaling pathway | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0060965 | negative regulation of gene silencing by miRNA | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0060795 | cell fate commitment involved in formation of primary germ layer | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0060177 | regulation of angiotensin metabolic process | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:2000629 | negative regulation of miRNA metabolic process | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0071338 | positive regulation of hair follicle cell proliferation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0060242 | contact inhibition | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0009786 | regulation of asymmetric cell division | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0060661 | submandibular salivary gland formation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0090043 | regulation of tubulin deacetylation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 2 | 2 |
GO:0071389 | cellular response to mineralocorticoid stimulus | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0014737 | positive regulation of muscle atrophy | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0090135 | actin filament branching | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0035984 | cellular response to trichostatin A | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0044324 | regulation of transcription involved in anterior/posterior axis specification | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0005829 | cytosol | 1.39e-03 | 1.00e+00 | 1.946 | 6 | 86 | 2496 |
GO:0051082 | unfolded protein binding | 1.44e-03 | 1.00e+00 | 5.107 | 2 | 7 | 93 |
GO:0051683 | establishment of Golgi localization | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0034191 | apolipoprotein A-I receptor binding | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0018076 | N-terminal peptidyl-lysine acetylation | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0060913 | cardiac cell fate determination | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0003161 | cardiac conduction system development | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0010560 | positive regulation of glycoprotein biosynthetic process | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0003130 | BMP signaling pathway involved in heart induction | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0006355 | regulation of transcription, DNA-templated | 2.16e-03 | 1.00e+00 | 2.685 | 4 | 43 | 997 |
GO:0097157 | pre-mRNA intronic binding | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0048664 | neuron fate determination | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0018393 | internal peptidyl-lysine acetylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0007021 | tubulin complex assembly | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0060684 | epithelial-mesenchymal cell signaling | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0051835 | positive regulation of synapse structural plasticity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0072384 | organelle transport along microtubule | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0044822 | poly(A) RNA binding | 2.67e-03 | 1.00e+00 | 2.602 | 4 | 50 | 1056 |
GO:0001714 | endodermal cell fate specification | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0070934 | CRD-mediated mRNA stabilization | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 5 |
GO:0036336 | dendritic cell migration | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0035088 | establishment or maintenance of apical/basal cell polarity | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0065004 | protein-DNA complex assembly | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0031256 | leading edge membrane | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0060298 | positive regulation of sarcomere organization | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0032025 | response to cobalt ion | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0007097 | nuclear migration | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0003334 | keratinocyte development | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0006974 | cellular response to DNA damage stimulus | 3.74e-03 | 1.00e+00 | 4.408 | 2 | 7 | 151 |
GO:0070937 | CRD-mediated mRNA stability complex | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 3 | 6 |
GO:0060789 | hair follicle placode formation | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 2 | 6 |
GO:0048554 | positive regulation of metalloenzyme activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0043497 | regulation of protein heterodimerization activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0051988 | regulation of attachment of spindle microtubules to kinetochore | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 2 | 7 |
GO:0051489 | regulation of filopodium assembly | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 1 | 7 |
GO:0006475 | internal protein amino acid acetylation | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 1 | 7 |
GO:0003677 | DNA binding | 4.51e-03 | 1.00e+00 | 2.396 | 4 | 49 | 1218 |
GO:0005667 | transcription factor complex | 4.98e-03 | 1.00e+00 | 4.195 | 2 | 17 | 175 |
GO:0001955 | blood vessel maturation | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 8 |
GO:0003714 | transcription corepressor activity | 5.15e-03 | 1.00e+00 | 4.170 | 2 | 11 | 178 |
GO:0035259 | glucocorticoid receptor binding | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0045793 | positive regulation of cell size | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 2 | 9 |
GO:0060765 | regulation of androgen receptor signaling pathway | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0090136 | epithelial cell-cell adhesion | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0006983 | ER overload response | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 1 | 9 |
GO:0005832 | chaperonin-containing T-complex | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 2 | 9 |
GO:0002199 | zona pellucida receptor complex | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 10 |
GO:0031274 | positive regulation of pseudopodium assembly | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 10 |
GO:0035413 | positive regulation of catenin import into nucleus | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 10 |
GO:0016407 | acetyltransferase activity | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 2 | 10 |
GO:0060047 | heart contraction | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 10 |
GO:0010467 | gene expression | 6.76e-03 | 1.00e+00 | 2.845 | 3 | 45 | 669 |
GO:0045662 | negative regulation of myoblast differentiation | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 3 | 11 |
GO:0043923 | positive regulation by host of viral transcription | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 11 |
GO:0033160 | positive regulation of protein import into nucleus, translocation | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 3 | 11 |
GO:0042975 | peroxisome proliferator activated receptor binding | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 11 |
GO:0060391 | positive regulation of SMAD protein import into nucleus | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 4 | 11 |
GO:0005838 | proteasome regulatory particle | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 12 |
GO:0035198 | miRNA binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 12 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 7.64e-03 | 1.00e+00 | 2.782 | 3 | 39 | 699 |
GO:0071480 | cellular response to gamma radiation | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 13 |
GO:0016746 | transferase activity, transferring acyl groups | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 13 |
GO:0051019 | mitogen-activated protein kinase binding | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 13 |
GO:0030234 | enzyme regulator activity | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 13 |
GO:0031333 | negative regulation of protein complex assembly | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0031996 | thioesterase binding | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0070542 | response to fatty acid | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0000242 | pericentriolar material | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 1 | 14 |
GO:0032993 | protein-DNA complex | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 14 |
GO:0003713 | transcription coactivator activity | 8.97e-03 | 1.00e+00 | 3.757 | 2 | 24 | 237 |
GO:0030225 | macrophage differentiation | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:0001824 | blastocyst development | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:0051233 | spindle midzone | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 2 | 15 |
GO:1990090 | cellular response to nerve growth factor stimulus | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 15 |
GO:0030742 | GTP-dependent protein binding | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 1 | 17 |
GO:0090316 | positive regulation of intracellular protein transport | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 2 | 17 |
GO:0022624 | proteasome accessory complex | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 1 | 17 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 1.07e-02 | 1.00e+00 | 2.607 | 3 | 41 | 789 |
GO:0007088 | regulation of mitosis | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 18 |
GO:0045773 | positive regulation of axon extension | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 18 |
GO:0033613 | activating transcription factor binding | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 3 | 18 |
GO:0046847 | filopodium assembly | 1.18e-02 | 1.00e+00 | 6.398 | 1 | 1 | 19 |
GO:0035257 | nuclear hormone receptor binding | 1.18e-02 | 1.00e+00 | 6.398 | 1 | 1 | 19 |
GO:0071549 | cellular response to dexamethasone stimulus | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 20 |
GO:0010942 | positive regulation of cell death | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 20 |
GO:0032757 | positive regulation of interleukin-8 production | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 20 |
GO:0031435 | mitogen-activated protein kinase kinase kinase binding | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 1 | 21 |
GO:0032967 | positive regulation of collagen biosynthetic process | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 3 | 21 |
GO:0045862 | positive regulation of proteolysis | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 2 | 21 |
GO:0000123 | histone acetyltransferase complex | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 6 | 21 |
GO:0031424 | keratinization | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 22 |
GO:0003823 | antigen binding | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 2 | 22 |
GO:0005720 | nuclear heterochromatin | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 2 | 22 |
GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 3 | 23 |
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 1 | 23 |
GO:0002040 | sprouting angiogenesis | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 2 | 23 |
GO:0051017 | actin filament bundle assembly | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 1 | 23 |
GO:0007163 | establishment or maintenance of cell polarity | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 2 | 24 |
GO:0043388 | positive regulation of DNA binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 2 | 24 |
GO:0043425 | bHLH transcription factor binding | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 24 |
GO:0051059 | NF-kappaB binding | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 3 | 25 |
GO:0007339 | binding of sperm to zona pellucida | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 2 | 25 |
GO:0035329 | hippo signaling | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 5 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 26 |
GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 26 |
GO:0051209 | release of sequestered calcium ion into cytosol | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 26 |
GO:0048565 | digestive tract development | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 2 | 26 |
GO:0045859 | regulation of protein kinase activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 26 |
GO:0051149 | positive regulation of muscle cell differentiation | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 4 | 27 |
GO:0032467 | positive regulation of cytokinesis | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 2 | 27 |
GO:0034612 | response to tumor necrosis factor | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 2 | 27 |
GO:0043967 | histone H4 acetylation | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 27 |
GO:0031069 | hair follicle morphogenesis | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 1 | 27 |
GO:0050714 | positive regulation of protein secretion | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 3 | 28 |
GO:0072686 | mitotic spindle | 1.80e-02 | 1.00e+00 | 5.788 | 1 | 3 | 29 |
GO:0043565 | sequence-specific DNA binding | 1.85e-02 | 1.00e+00 | 3.212 | 2 | 11 | 346 |
GO:0031647 | regulation of protein stability | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 4 | 30 |
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 30 |
GO:0042594 | response to starvation | 1.92e-02 | 1.00e+00 | 5.692 | 1 | 4 | 31 |
GO:0043491 | protein kinase B signaling | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 32 |
GO:1903507 | negative regulation of nucleic acid-templated transcription | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 32 |
GO:0001756 | somitogenesis | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 33 |
GO:0071333 | cellular response to glucose stimulus | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 33 |
GO:0042692 | muscle cell differentiation | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 4 | 34 |
GO:0034332 | adherens junction organization | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 36 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 36 |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 36 |
GO:0045740 | positive regulation of DNA replication | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 2.29e-02 | 1.00e+00 | 5.437 | 1 | 5 | 37 |
GO:0000278 | mitotic cell cycle | 2.33e-02 | 1.00e+00 | 3.035 | 2 | 15 | 391 |
GO:0031490 | chromatin DNA binding | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 2 | 38 |
GO:0032092 | positive regulation of protein binding | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 38 |
GO:0046332 | SMAD binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 2 | 40 |
GO:0071320 | cellular response to cAMP | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 40 |
GO:0035019 | somatic stem cell maintenance | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 6 | 40 |
GO:0007519 | skeletal muscle tissue development | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 2 | 40 |
GO:0070301 | cellular response to hydrogen peroxide | 2.53e-02 | 1.00e+00 | 5.289 | 1 | 2 | 41 |
GO:0004402 | histone acetyltransferase activity | 2.65e-02 | 1.00e+00 | 5.220 | 1 | 6 | 43 |
GO:0021762 | substantia nigra development | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 44 |
GO:0034613 | cellular protein localization | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 44 |
GO:0045727 | positive regulation of translation | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 44 |
GO:0043966 | histone H3 acetylation | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 5 | 45 |
GO:0001047 | core promoter binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 5 | 45 |
GO:0044297 | cell body | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 2 | 46 |
GO:0007030 | Golgi organization | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 3 | 49 |
GO:0001669 | acrosomal vesicle | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 2 | 49 |
GO:0035690 | cellular response to drug | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 3 | 49 |
GO:0006521 | regulation of cellular amino acid metabolic process | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 50 |
GO:0006986 | response to unfolded protein | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 4 | 50 |
GO:0030175 | filopodium | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 50 |
GO:0034976 | response to endoplasmic reticulum stress | 3.14e-02 | 1.00e+00 | 4.974 | 1 | 2 | 51 |
GO:0045454 | cell redox homeostasis | 3.14e-02 | 1.00e+00 | 4.974 | 1 | 1 | 51 |
GO:0009611 | response to wounding | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 5 | 52 |
GO:0007623 | circadian rhythm | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 53 |
GO:0005634 | nucleus | 3.27e-02 | 1.00e+00 | 1.077 | 6 | 159 | 4559 |
GO:0044267 | cellular protein metabolic process | 3.33e-02 | 1.00e+00 | 2.757 | 2 | 20 | 474 |
GO:0051592 | response to calcium ion | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 1 | 55 |
GO:0002039 | p53 binding | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 4 | 55 |
GO:0046330 | positive regulation of JNK cascade | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 2 | 55 |
GO:0071300 | cellular response to retinoic acid | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 1 | 55 |
GO:0043627 | response to estrogen | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 5 | 56 |
GO:0000502 | proteasome complex | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 3 | 58 |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 3.62e-02 | 1.00e+00 | 4.764 | 1 | 2 | 59 |
GO:0006396 | RNA processing | 3.62e-02 | 1.00e+00 | 4.764 | 1 | 5 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 3.62e-02 | 1.00e+00 | 4.764 | 1 | 6 | 59 |
GO:0008013 | beta-catenin binding | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 9 | 60 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 3.74e-02 | 1.00e+00 | 4.715 | 1 | 2 | 61 |
GO:0032481 | positive regulation of type I interferon production | 3.74e-02 | 1.00e+00 | 4.715 | 1 | 6 | 61 |
GO:0030141 | secretory granule | 3.80e-02 | 1.00e+00 | 4.692 | 1 | 4 | 62 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 3.86e-02 | 1.00e+00 | 4.669 | 1 | 4 | 63 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 1 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 2 | 65 |
GO:0031295 | T cell costimulation | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 1 | 65 |
GO:0035264 | multicellular organism growth | 4.11e-02 | 1.00e+00 | 4.580 | 1 | 2 | 67 |
GO:0016032 | viral process | 4.14e-02 | 1.00e+00 | 2.585 | 2 | 26 | 534 |
GO:0010468 | regulation of gene expression | 4.17e-02 | 1.00e+00 | 4.559 | 1 | 2 | 68 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.29e-02 | 1.00e+00 | 4.517 | 1 | 2 | 70 |
GO:0006334 | nucleosome assembly | 4.41e-02 | 1.00e+00 | 4.476 | 1 | 3 | 72 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 4.41e-02 | 1.00e+00 | 4.476 | 1 | 1 | 72 |
GO:0030324 | lung development | 4.41e-02 | 1.00e+00 | 4.476 | 1 | 1 | 72 |
GO:0006915 | apoptotic process | 4.45e-02 | 1.00e+00 | 2.530 | 2 | 12 | 555 |
GO:0000785 | chromatin | 4.47e-02 | 1.00e+00 | 4.456 | 1 | 6 | 73 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 2 | 74 |
GO:0000981 | sequence-specific DNA binding RNA polymerase II transcription factor activity | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 4 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 2 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 4.59e-02 | 1.00e+00 | 4.417 | 1 | 1 | 75 |
GO:0060070 | canonical Wnt signaling pathway | 4.59e-02 | 1.00e+00 | 4.417 | 1 | 4 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 4.59e-02 | 1.00e+00 | 4.417 | 1 | 1 | 75 |
GO:0001889 | liver development | 4.70e-02 | 1.00e+00 | 4.379 | 1 | 3 | 77 |
GO:0010629 | negative regulation of gene expression | 4.70e-02 | 1.00e+00 | 4.379 | 1 | 4 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 7 | 78 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 4.82e-02 | 1.00e+00 | 4.342 | 1 | 2 | 79 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 4.82e-02 | 1.00e+00 | 4.342 | 1 | 2 | 79 |
GO:0045177 | apical part of cell | 4.94e-02 | 1.00e+00 | 4.306 | 1 | 3 | 81 |
GO:0009653 | anatomical structure morphogenesis | 5.06e-02 | 1.00e+00 | 4.271 | 1 | 2 | 83 |
GO:0045087 | innate immune response | 5.06e-02 | 1.00e+00 | 2.427 | 2 | 15 | 596 |
GO:0009887 | organ morphogenesis | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 5 | 86 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 8 | 86 |
GO:0045471 | response to ethanol | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 3 | 86 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 5.60e-02 | 1.00e+00 | 4.123 | 1 | 1 | 92 |
GO:0001649 | osteoblast differentiation | 5.60e-02 | 1.00e+00 | 4.123 | 1 | 5 | 92 |
GO:0071456 | cellular response to hypoxia | 5.60e-02 | 1.00e+00 | 4.123 | 1 | 3 | 92 |
GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity | 5.60e-02 | 1.00e+00 | 4.123 | 1 | 7 | 92 |
GO:0005770 | late endosome | 5.66e-02 | 1.00e+00 | 4.107 | 1 | 2 | 93 |
GO:0005737 | cytoplasm | 5.81e-02 | 1.00e+00 | 1.089 | 5 | 124 | 3767 |
GO:0051726 | regulation of cell cycle | 5.89e-02 | 1.00e+00 | 4.046 | 1 | 5 | 97 |
GO:0001934 | positive regulation of protein phosphorylation | 6.31e-02 | 1.00e+00 | 3.946 | 1 | 5 | 104 |
GO:0030496 | midbody | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 2 | 108 |
GO:0005815 | microtubule organizing center | 6.60e-02 | 1.00e+00 | 3.878 | 1 | 3 | 109 |
GO:0030529 | ribonucleoprotein complex | 6.78e-02 | 1.00e+00 | 3.839 | 1 | 5 | 112 |
GO:0051056 | regulation of small GTPase mediated signal transduction | 6.95e-02 | 1.00e+00 | 3.801 | 1 | 3 | 115 |
GO:0000209 | protein polyubiquitination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 3 | 116 |
GO:0006325 | chromatin organization | 7.13e-02 | 1.00e+00 | 3.764 | 1 | 12 | 118 |
GO:0007219 | Notch signaling pathway | 7.25e-02 | 1.00e+00 | 3.739 | 1 | 5 | 120 |
GO:0030036 | actin cytoskeleton organization | 7.42e-02 | 1.00e+00 | 3.704 | 1 | 3 | 123 |
GO:0007050 | cell cycle arrest | 7.48e-02 | 1.00e+00 | 3.692 | 1 | 5 | 124 |
GO:0016020 | membrane | 7.75e-02 | 1.00e+00 | 1.516 | 3 | 46 | 1681 |
GO:0005911 | cell-cell junction | 8.18e-02 | 1.00e+00 | 3.559 | 1 | 2 | 136 |
GO:0000086 | G2/M transition of mitotic cell cycle | 8.18e-02 | 1.00e+00 | 3.559 | 1 | 4 | 136 |
GO:0016055 | Wnt signaling pathway | 8.29e-02 | 1.00e+00 | 3.538 | 1 | 4 | 138 |
GO:0007507 | heart development | 8.35e-02 | 1.00e+00 | 3.527 | 1 | 7 | 139 |
GO:0006457 | protein folding | 8.58e-02 | 1.00e+00 | 3.486 | 1 | 7 | 143 |
GO:0010628 | positive regulation of gene expression | 8.75e-02 | 1.00e+00 | 3.456 | 1 | 7 | 146 |
GO:0001666 | response to hypoxia | 8.92e-02 | 1.00e+00 | 3.427 | 1 | 7 | 149 |
GO:0000082 | G1/S transition of mitotic cell cycle | 8.92e-02 | 1.00e+00 | 3.427 | 1 | 3 | 149 |
GO:0042981 | regulation of apoptotic process | 8.98e-02 | 1.00e+00 | 3.417 | 1 | 4 | 150 |
GO:0043005 | neuron projection | 9.38e-02 | 1.00e+00 | 3.352 | 1 | 3 | 157 |
GO:0000398 | mRNA splicing, via spliceosome | 9.78e-02 | 1.00e+00 | 3.289 | 1 | 15 | 164 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 9.84e-02 | 1.00e+00 | 3.280 | 1 | 12 | 165 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.02e-01 | 1.00e+00 | 3.228 | 1 | 2 | 171 |
GO:0031625 | ubiquitin protein ligase binding | 1.06e-01 | 1.00e+00 | 3.170 | 1 | 5 | 178 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 22 | 184 |
GO:0032403 | protein complex binding | 1.09e-01 | 1.00e+00 | 3.130 | 1 | 6 | 183 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.12e-01 | 1.00e+00 | 3.084 | 1 | 5 | 189 |
GO:0003924 | GTPase activity | 1.16e-01 | 1.00e+00 | 3.024 | 1 | 7 | 197 |
GO:0006184 | GTP catabolic process | 1.26e-01 | 1.00e+00 | 2.905 | 1 | 7 | 214 |
GO:0016071 | mRNA metabolic process | 1.31e-01 | 1.00e+00 | 2.845 | 1 | 8 | 223 |
GO:0008380 | RNA splicing | 1.34e-01 | 1.00e+00 | 2.813 | 1 | 22 | 228 |
GO:0007399 | nervous system development | 1.35e-01 | 1.00e+00 | 2.794 | 1 | 6 | 231 |
GO:0043025 | neuronal cell body | 1.43e-01 | 1.00e+00 | 2.710 | 1 | 9 | 245 |
GO:0016070 | RNA metabolic process | 1.44e-01 | 1.00e+00 | 2.698 | 1 | 8 | 247 |
GO:0005874 | microtubule | 1.45e-01 | 1.00e+00 | 2.686 | 1 | 7 | 249 |
GO:0007264 | small GTPase mediated signal transduction | 1.61e-01 | 1.00e+00 | 2.522 | 1 | 3 | 279 |
GO:0070062 | extracellular vesicular exosome | 1.78e-01 | 1.00e+00 | 1.002 | 3 | 57 | 2400 |
GO:0005525 | GTP binding | 1.78e-01 | 1.00e+00 | 2.370 | 1 | 12 | 310 |
GO:0019901 | protein kinase binding | 1.81e-01 | 1.00e+00 | 2.338 | 1 | 18 | 317 |
GO:0007411 | axon guidance | 1.82e-01 | 1.00e+00 | 2.329 | 1 | 5 | 319 |
GO:0005813 | centrosome | 1.86e-01 | 1.00e+00 | 2.297 | 1 | 7 | 326 |
GO:0008283 | cell proliferation | 1.87e-01 | 1.00e+00 | 2.289 | 1 | 14 | 328 |
GO:0003682 | chromatin binding | 1.87e-01 | 1.00e+00 | 2.293 | 1 | 19 | 327 |
GO:0005524 | ATP binding | 1.91e-01 | 1.00e+00 | 1.304 | 2 | 31 | 1298 |
GO:0003723 | RNA binding | 1.94e-01 | 1.00e+00 | 2.228 | 1 | 18 | 342 |
GO:0000139 | Golgi membrane | 2.04e-01 | 1.00e+00 | 2.150 | 1 | 7 | 361 |
GO:0005925 | focal adhesion | 2.07e-01 | 1.00e+00 | 2.130 | 1 | 9 | 366 |
GO:0046982 | protein heterodimerization activity | 2.14e-01 | 1.00e+00 | 2.076 | 1 | 8 | 380 |
GO:0009986 | cell surface | 2.25e-01 | 1.00e+00 | 1.995 | 1 | 9 | 402 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.30e-01 | 1.00e+00 | 1.956 | 1 | 24 | 413 |
GO:0006366 | transcription from RNA polymerase II promoter | 2.33e-01 | 1.00e+00 | 1.935 | 1 | 30 | 419 |
GO:0043066 | negative regulation of apoptotic process | 2.36e-01 | 1.00e+00 | 1.918 | 1 | 16 | 424 |
GO:0007596 | blood coagulation | 2.51e-01 | 1.00e+00 | 1.816 | 1 | 11 | 455 |
GO:0045893 | positive regulation of transcription, DNA-templated | 2.62e-01 | 1.00e+00 | 1.745 | 1 | 24 | 478 |
GO:0042802 | identical protein binding | 2.65e-01 | 1.00e+00 | 1.727 | 1 | 19 | 484 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 3.04e-01 | 1.00e+00 | 1.491 | 1 | 37 | 570 |
GO:0005794 | Golgi apparatus | 3.22e-01 | 1.00e+00 | 1.393 | 1 | 9 | 610 |
GO:0008270 | zinc ion binding | 4.75e-01 | 1.00e+00 | 0.685 | 1 | 27 | 997 |
GO:0044281 | small molecule metabolic process | 5.46e-01 | 1.00e+00 | 0.404 | 1 | 20 | 1211 |
GO:0006351 | transcription, DNA-templated | 6.14e-01 | 1.00e+00 | 0.148 | 1 | 57 | 1446 |
GO:0005730 | nucleolus | 6.63e-01 | 1.00e+00 | -0.034 | 1 | 66 | 1641 |
GO:0005886 | plasma membrane | 8.31e-01 | 1.00e+00 | -0.688 | 1 | 49 | 2582 |