int-snw-463

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.108	1.36e-18	1.23e-05	2.52e-04

chia-screen-data-Fav-int-snw-463 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
[ ZFHX3 ]	463	1	-1.296	3.108	8	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
SON	6651	9	-3.844	3.108	9	Yes	Yes
PRPF40A	55660	2	-1.511	3.108	199	-	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ZFHX3	463	PRPF40A	55660	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
SON	6651	PRPF40A	55660	pp	--	int.I2D: BIND, MINT, HPRD; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
ZFHX3	463	POU5F1	5460	pp	--	int.I2D: IntAct_Mouse
HNRNPU	3192	PRPF40A	55660	pp	--	int.I2D: BioGrid, Pawson1

Related GO terms (119)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006366	transcription from RNA polymerase II promoter	2.31e-06	3.33e-02	4.257	5	30	419
GO:0008380	RNA splicing	7.20e-06	1.04e-01	4.813	4	22	228
GO:0044212	transcription regulatory region DNA binding	1.24e-04	1.00e+00	4.839	3	17	168
GO:0016607	nuclear speck	1.33e-04	1.00e+00	4.805	3	12	172
GO:0006355	regulation of transcription, DNA-templated	1.56e-04	1.00e+00	3.007	5	43	997
GO:0044822	poly(A) RNA binding	2.05e-04	1.00e+00	2.924	5	50	1056
GO:0005654	nucleoplasm	2.30e-04	1.00e+00	2.889	5	64	1082
GO:0060795	cell fate commitment involved in formation of primary germ layer	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	6.24e-04	1.00e+00	10.646	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	6.24e-04	1.00e+00	10.646	1	1	1
GO:0005634	nucleus	6.43e-04	1.00e+00	1.492	8	159	4559
GO:0003723	RNA binding	9.98e-04	1.00e+00	3.813	3	18	342
GO:0019046	release from viral latency	1.25e-03	1.00e+00	9.646	1	2	2
GO:0009786	regulation of asymmetric cell division	1.25e-03	1.00e+00	9.646	1	1	2
GO:0060242	contact inhibition	1.25e-03	1.00e+00	9.646	1	1	2
GO:0060913	cardiac cell fate determination	1.87e-03	1.00e+00	9.061	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.87e-03	1.00e+00	9.061	1	1	3
GO:0070461	SAGA-type complex	3.12e-03	1.00e+00	8.324	1	2	5
GO:0001714	endodermal cell fate specification	3.12e-03	1.00e+00	8.324	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	3.12e-03	1.00e+00	8.324	1	2	5
GO:0050733	RS domain binding	3.74e-03	1.00e+00	8.061	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	3.74e-03	1.00e+00	8.061	1	3	6
GO:0006397	mRNA processing	4.18e-03	1.00e+00	4.324	2	10	160
GO:0000398	mRNA splicing, via spliceosome	4.39e-03	1.00e+00	4.289	2	15	164
GO:0003677	DNA binding	4.51e-03	1.00e+00	2.396	4	49	1218
GO:0007049	cell cycle	4.93e-03	1.00e+00	4.203	2	6	174
GO:0070688	MLL5-L complex	4.98e-03	1.00e+00	7.646	1	1	8
GO:0043254	regulation of protein complex assembly	4.98e-03	1.00e+00	7.646	1	1	8
GO:0005667	transcription factor complex	4.98e-03	1.00e+00	4.195	2	17	175
GO:0005515	protein binding	5.23e-03	1.00e+00	1.090	8	198	6024
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0048188	Set1C/COMPASS complex	5.60e-03	1.00e+00	7.476	1	4	9
GO:0035413	positive regulation of catenin import into nucleus	6.22e-03	1.00e+00	7.324	1	2	10
GO:0010467	gene expression	6.76e-03	1.00e+00	2.845	3	45	669
GO:0045662	negative regulation of myoblast differentiation	6.85e-03	1.00e+00	7.187	1	3	11
GO:0045663	positive regulation of myoblast differentiation	6.85e-03	1.00e+00	7.187	1	2	11
GO:0060391	positive regulation of SMAD protein import into nucleus	6.85e-03	1.00e+00	7.187	1	4	11
GO:0035198	miRNA binding	7.47e-03	1.00e+00	7.061	1	1	12
GO:0003700	sequence-specific DNA binding transcription factor activity	7.64e-03	1.00e+00	2.782	3	39	699
GO:0071480	cellular response to gamma radiation	8.09e-03	1.00e+00	6.946	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	8.09e-03	1.00e+00	6.946	1	2	13
GO:0031011	Ino80 complex	8.70e-03	1.00e+00	6.839	1	6	14
GO:0032465	regulation of cytokinesis	8.70e-03	1.00e+00	6.839	1	1	14
GO:0003713	transcription coactivator activity	8.97e-03	1.00e+00	3.757	2	24	237
GO:0043981	histone H4-K5 acetylation	9.32e-03	1.00e+00	6.739	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	9.32e-03	1.00e+00	6.739	1	3	15
GO:0001824	blastocyst development	9.32e-03	1.00e+00	6.739	1	2	15
GO:0043982	histone H4-K8 acetylation	9.32e-03	1.00e+00	6.739	1	5	15
GO:0043274	phospholipase binding	9.94e-03	1.00e+00	6.646	1	1	16
GO:0045664	regulation of neuron differentiation	1.12e-02	1.00e+00	6.476	1	1	18
GO:0070064	proline-rich region binding	1.12e-02	1.00e+00	6.476	1	1	18
GO:0043984	histone H4-K16 acetylation	1.18e-02	1.00e+00	6.398	1	5	19
GO:0000123	histone acetyltransferase complex	1.30e-02	1.00e+00	6.254	1	6	21
GO:0005730	nucleolus	1.31e-02	1.00e+00	1.966	4	66	1641
GO:0036464	cytoplasmic ribonucleoprotein granule	1.36e-02	1.00e+00	6.187	1	2	22
GO:0045787	positive regulation of cell cycle	1.36e-02	1.00e+00	6.187	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.36e-02	1.00e+00	6.187	1	4	22
GO:0043484	regulation of RNA splicing	1.36e-02	1.00e+00	6.187	1	1	22
GO:0035329	hippo signaling	1.61e-02	1.00e+00	5.946	1	5	26
GO:0071339	MLL1 complex	1.67e-02	1.00e+00	5.891	1	6	27
GO:0043565	sequence-specific DNA binding	1.85e-02	1.00e+00	3.212	2	11	346
GO:1903507	negative regulation of nucleic acid-templated transcription	1.98e-02	1.00e+00	5.646	1	2	32
GO:0035019	somatic stem cell maintenance	2.47e-02	1.00e+00	5.324	1	6	40
GO:0031124	mRNA 3'-end processing	2.59e-02	1.00e+00	5.254	1	2	42
GO:0006369	termination of RNA polymerase II transcription	2.77e-02	1.00e+00	5.154	1	2	45
GO:0000910	cytokinesis	3.14e-02	1.00e+00	4.974	1	2	51
GO:0009611	response to wounding	3.20e-02	1.00e+00	4.946	1	5	52
GO:0000226	microtubule cytoskeleton organization	3.20e-02	1.00e+00	4.946	1	2	52
GO:0006396	RNA processing	3.62e-02	1.00e+00	4.764	1	5	59
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	3.74e-02	1.00e+00	4.715	1	4	61
GO:0006406	mRNA export from nucleus	3.74e-02	1.00e+00	4.715	1	4	61
GO:0006310	DNA recombination	3.98e-02	1.00e+00	4.624	1	7	65
GO:0010468	regulation of gene expression	4.17e-02	1.00e+00	4.559	1	2	68
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.53e-02	1.00e+00	4.437	1	4	74
GO:0002020	protease binding	4.53e-02	1.00e+00	4.437	1	6	74
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.67e-02	1.00e+00	2.491	2	37	570
GO:0071013	catalytic step 2 spliceosome	4.76e-02	1.00e+00	4.361	1	7	78
GO:0051301	cell division	4.94e-02	1.00e+00	4.306	1	2	81
GO:0007517	muscle organ development	5.06e-02	1.00e+00	4.271	1	4	83
GO:0009653	anatomical structure morphogenesis	5.06e-02	1.00e+00	4.271	1	2	83
GO:0050821	protein stabilization	5.36e-02	1.00e+00	4.187	1	3	88
GO:0007010	cytoskeleton organization	5.54e-02	1.00e+00	4.138	1	4	91
GO:0016363	nuclear matrix	5.54e-02	1.00e+00	4.138	1	6	91
GO:0001649	osteoblast differentiation	5.60e-02	1.00e+00	4.123	1	5	92
GO:0005737	cytoplasm	5.81e-02	1.00e+00	1.089	5	124	3767
GO:0051726	regulation of cell cycle	5.89e-02	1.00e+00	4.046	1	5	97
GO:0008360	regulation of cell shape	6.25e-02	1.00e+00	3.960	1	4	103
GO:0003676	nucleic acid binding	6.48e-02	1.00e+00	3.905	1	2	107
GO:0030529	ribonucleoprotein complex	6.78e-02	1.00e+00	3.839	1	5	112
GO:0006325	chromatin organization	7.13e-02	1.00e+00	3.764	1	12	118
GO:0007050	cell cycle arrest	7.48e-02	1.00e+00	3.692	1	5	124
GO:0016477	cell migration	7.71e-02	1.00e+00	3.646	1	4	128
GO:0016020	membrane	7.75e-02	1.00e+00	1.516	3	46	1681
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	8.33e-02	1.00e+00	2.022	2	41	789
GO:0010628	positive regulation of gene expression	8.75e-02	1.00e+00	3.456	1	7	146
GO:0006974	cellular response to DNA damage stimulus	9.04e-02	1.00e+00	3.408	1	7	151
GO:0007420	brain development	9.95e-02	1.00e+00	3.262	1	2	167
GO:0031625	ubiquitin protein ligase binding	1.06e-01	1.00e+00	3.170	1	5	178
GO:0003714	transcription corepressor activity	1.06e-01	1.00e+00	3.170	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.09e-01	1.00e+00	3.123	1	22	184
GO:0005739	mitochondrion	1.25e-01	1.00e+00	1.683	2	23	998
GO:0008134	transcription factor binding	1.41e-01	1.00e+00	2.727	1	18	242
GO:0043025	neuronal cell body	1.43e-01	1.00e+00	2.710	1	9	245
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.629	1	13	259
GO:0006281	DNA repair	1.52e-01	1.00e+00	2.618	1	14	261
GO:0006954	inflammatory response	1.60e-01	1.00e+00	2.532	1	6	277
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.532	1	9	277
GO:0003682	chromatin binding	1.87e-01	1.00e+00	2.293	1	19	327
GO:0008283	cell proliferation	1.87e-01	1.00e+00	2.289	1	14	328
GO:0009986	cell surface	2.25e-01	1.00e+00	1.995	1	9	402
GO:0045892	negative regulation of transcription, DNA-templated	2.30e-01	1.00e+00	1.956	1	24	413
GO:0043066	negative regulation of apoptotic process	2.36e-01	1.00e+00	1.918	1	16	424
GO:0042802	identical protein binding	2.65e-01	1.00e+00	1.727	1	19	484
GO:0008270	zinc ion binding	4.75e-01	1.00e+00	0.685	1	27	997
GO:0005829	cytosol	4.79e-01	1.00e+00	0.361	2	86	2496
GO:0005524	ATP binding	5.72e-01	1.00e+00	0.304	1	31	1298

chia-Fav

int-snw-463

Statistics

Genes (9)

Interactions (9)

Related GO terms (119)