int-snw-3883

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.804	3.55e-15	6.98e-04	4.39e-03

chia-screen-data-Fav-int-snw-3883 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
TGFB1	7040	2	-1.997	2.821	60	-	-
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
TCP1	6950	10	-2.383	3.119	241	Yes	-
MCRS1	10445	14	-2.660	3.079	63	Yes	Yes
[ KRT33A ]	3883	1	-1.279	2.804	4	-	-
SYNCRIP	10492	9	-2.401	3.197	103	Yes	Yes
EPS15	2060	2	-1.912	2.837	75	-	-
SH3BP4	23677	2	-2.354	2.837	33	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
INO80E	283899	10	-2.663	3.079	20	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
ITSN2	50618	2	-2.012	3.079	50	Yes	-
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (17)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFRKB	4798	MCRS1	10445	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
SYNCRIP	10492	ITSN2	50618	pp	--	int.I2D: Jorgensen_EphR
DDIT3	1649	TCP1	6950	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	SYNCRIP	10492	pp	--	int.Mint: MI:0915(physical association)
EPS15	2060	TGFB1	7040	pp	--	int.I2D: BioGrid
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
TCP1	6950	SH3BP4	23677	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
EPS15	2060	KRT33A	3883	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
MCRS1	10445	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
PSMD2	5708	TCP1	6950	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow
EPS15	2060	ITSN2	50618	pp	--	int.I2D: Jorgensen_EphR
MCRS1	10445	ITSN2	50618	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
EPS15	2060	SH3BP4	23677	pp	--	int.I2D: BIND, MINT; int.Mint: MI:0915(physical association)
NFRKB	4798	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid

Related GO terms (342)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0031011	Ino80 complex	3.29e-07	4.75e-03	7.687	3	6	14
GO:0070934	CRD-mediated mRNA stabilization	1.01e-05	1.45e-01	8.587	2	2	5
GO:0070937	CRD-mediated mRNA stability complex	1.51e-05	2.18e-01	8.324	2	3	6
GO:0006310	DNA recombination	3.82e-05	5.52e-01	5.472	3	7	65
GO:0005515	protein binding	4.46e-05	6.44e-01	1.160	14	198	6024
GO:0005654	nucleoplasm	4.94e-05	7.12e-01	2.637	7	64	1082
GO:0045662	negative regulation of myoblast differentiation	5.52e-05	7.97e-01	7.450	2	3	11
GO:0060391	positive regulation of SMAD protein import into nucleus	5.52e-05	7.97e-01	7.450	2	4	11
GO:0042789	mRNA transcription from RNA polymerase II promoter	7.82e-05	1.00e+00	7.209	2	2	13
GO:0006897	endocytosis	1.65e-04	1.00e+00	4.766	3	7	106
GO:0006355	regulation of transcription, DNA-templated	3.13e-04	1.00e+00	2.533	6	43	997
GO:0044212	transcription regulatory region DNA binding	6.37e-04	1.00e+00	4.102	3	17	168
GO:2000016	negative regulation of determination of dorsal identity	1.04e-03	1.00e+00	9.909	1	1	1
GO:0009817	defense response to fungus, incompatible interaction	1.04e-03	1.00e+00	9.909	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	1.04e-03	1.00e+00	9.909	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	1.04e-03	1.00e+00	9.909	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	1.04e-03	1.00e+00	9.909	1	1	1
GO:0043090	amino acid import	1.04e-03	1.00e+00	9.909	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1.04e-03	1.00e+00	9.909	1	1	1
GO:0010742	macrophage derived foam cell differentiation	1.04e-03	1.00e+00	9.909	1	1	1
GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity	1.04e-03	1.00e+00	9.909	1	1	1
GO:0061035	regulation of cartilage development	1.04e-03	1.00e+00	9.909	1	1	1
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.04e-03	1.00e+00	9.909	1	1	1
GO:0060751	branch elongation involved in mammary gland duct branching	1.04e-03	1.00e+00	9.909	1	1	1
GO:0005905	coated pit	1.20e-03	1.00e+00	5.265	2	6	50
GO:0009611	response to wounding	1.30e-03	1.00e+00	5.209	2	5	52
GO:0006396	RNA processing	1.67e-03	1.00e+00	5.027	2	5	59
GO:0060242	contact inhibition	2.08e-03	1.00e+00	8.909	1	1	2
GO:0045066	regulatory T cell differentiation	2.08e-03	1.00e+00	8.909	1	1	2
GO:0048298	positive regulation of isotype switching to IgA isotypes	2.08e-03	1.00e+00	8.909	1	1	2
GO:0060312	regulation of blood vessel remodeling	2.08e-03	1.00e+00	8.909	1	1	2
GO:0032943	mononuclear cell proliferation	2.08e-03	1.00e+00	8.909	1	1	2
GO:0046732	active induction of host immune response by virus	2.08e-03	1.00e+00	8.909	1	1	2
GO:1901203	positive regulation of extracellular matrix assembly	2.08e-03	1.00e+00	8.909	1	1	2
GO:0009786	regulation of asymmetric cell division	2.08e-03	1.00e+00	8.909	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2.08e-03	1.00e+00	8.909	1	1	2
GO:2000628	regulation of miRNA metabolic process	2.08e-03	1.00e+00	8.909	1	1	2
GO:0043932	ossification involved in bone remodeling	2.08e-03	1.00e+00	8.909	1	1	2
GO:0019049	evasion or tolerance of host defenses by virus	2.08e-03	1.00e+00	8.909	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	2.08e-03	1.00e+00	8.909	1	1	2
GO:0006281	DNA repair	2.27e-03	1.00e+00	3.466	3	14	261
GO:0071013	catalytic step 2 spliceosome	2.90e-03	1.00e+00	4.624	2	7	78
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	3.12e-03	1.00e+00	8.324	1	1	3
GO:0042306	regulation of protein import into nucleus	3.12e-03	1.00e+00	8.324	1	2	3
GO:0060913	cardiac cell fate determination	3.12e-03	1.00e+00	8.324	1	1	3
GO:0002513	tolerance induction to self antigen	3.12e-03	1.00e+00	8.324	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	3.12e-03	1.00e+00	8.324	1	1	3
GO:0061462	protein localization to lysosome	3.12e-03	1.00e+00	8.324	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	3.12e-03	1.00e+00	8.324	1	1	3
GO:0001649	osteoblast differentiation	4.00e-03	1.00e+00	4.386	2	5	92
GO:0010936	negative regulation of macrophage cytokine production	4.15e-03	1.00e+00	7.909	1	1	4
GO:0097452	GAIT complex	4.15e-03	1.00e+00	7.909	1	1	4
GO:0051152	positive regulation of smooth muscle cell differentiation	4.15e-03	1.00e+00	7.909	1	1	4
GO:0060364	frontal suture morphogenesis	4.15e-03	1.00e+00	7.909	1	1	4
GO:0007021	tubulin complex assembly	4.15e-03	1.00e+00	7.909	1	1	4
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	4.15e-03	1.00e+00	7.909	1	1	4
GO:0010716	negative regulation of extracellular matrix disassembly	4.15e-03	1.00e+00	7.909	1	2	4
GO:0031536	positive regulation of exit from mitosis	4.15e-03	1.00e+00	7.909	1	1	4
GO:0001714	endodermal cell fate specification	5.19e-03	1.00e+00	7.587	1	1	5
GO:0007182	common-partner SMAD protein phosphorylation	5.19e-03	1.00e+00	7.587	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	5.19e-03	1.00e+00	7.587	1	1	5
GO:0042482	positive regulation of odontogenesis	5.19e-03	1.00e+00	7.587	1	1	5
GO:0051098	regulation of binding	5.19e-03	1.00e+00	7.587	1	1	5
GO:0016202	regulation of striated muscle tissue development	5.19e-03	1.00e+00	7.587	1	1	5
GO:0051101	regulation of DNA binding	5.19e-03	1.00e+00	7.587	1	1	5
GO:0005634	nucleus	5.55e-03	1.00e+00	1.077	10	159	4559
GO:0030308	negative regulation of cell growth	5.67e-03	1.00e+00	4.128	2	6	110
GO:0030529	ribonucleoprotein complex	5.87e-03	1.00e+00	4.102	2	5	112
GO:0060744	mammary gland branching involved in thelarche	6.22e-03	1.00e+00	7.324	1	2	6
GO:0085029	extracellular matrix assembly	6.22e-03	1.00e+00	7.324	1	1	6
GO:0007435	salivary gland morphogenesis	6.22e-03	1.00e+00	7.324	1	1	6
GO:0007406	negative regulation of neuroblast proliferation	6.22e-03	1.00e+00	7.324	1	1	6
GO:0071204	histone pre-mRNA 3'end processing complex	6.22e-03	1.00e+00	7.324	1	1	6
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	6.22e-03	1.00e+00	7.324	1	2	6
GO:0007050	cell cycle arrest	7.16e-03	1.00e+00	3.955	2	5	124
GO:0032930	positive regulation of superoxide anion generation	7.26e-03	1.00e+00	7.102	1	2	7
GO:0050765	negative regulation of phagocytosis	7.26e-03	1.00e+00	7.102	1	1	7
GO:0007184	SMAD protein import into nucleus	7.26e-03	1.00e+00	7.102	1	1	7
GO:0005114	type II transforming growth factor beta receptor binding	7.26e-03	1.00e+00	7.102	1	1	7
GO:0005092	GDP-dissociation inhibitor activity	7.26e-03	1.00e+00	7.102	1	1	7
GO:0032801	receptor catabolic process	7.26e-03	1.00e+00	7.102	1	1	7
GO:0070723	response to cholesterol	7.26e-03	1.00e+00	7.102	1	1	7
GO:0001955	blood vessel maturation	8.29e-03	1.00e+00	6.909	1	1	8
GO:0034616	response to laminar fluid shear stress	8.29e-03	1.00e+00	6.909	1	1	8
GO:0048642	negative regulation of skeletal muscle tissue development	8.29e-03	1.00e+00	6.909	1	1	8
GO:0010763	positive regulation of fibroblast migration	8.29e-03	1.00e+00	6.909	1	1	8
GO:0007183	SMAD protein complex assembly	8.29e-03	1.00e+00	6.909	1	1	8
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	9.32e-03	1.00e+00	6.739	1	5	9
GO:2000679	positive regulation of transcription regulatory region DNA binding	9.32e-03	1.00e+00	6.739	1	1	9
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	9.32e-03	1.00e+00	6.739	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	9.32e-03	1.00e+00	6.739	1	5	9
GO:0006983	ER overload response	9.32e-03	1.00e+00	6.739	1	1	9
GO:0031065	positive regulation of histone deacetylation	9.32e-03	1.00e+00	6.739	1	2	9
GO:0005832	chaperonin-containing T-complex	9.32e-03	1.00e+00	6.739	1	2	9
GO:0002199	zona pellucida receptor complex	1.04e-02	1.00e+00	6.587	1	2	10
GO:0030122	AP-2 adaptor complex	1.04e-02	1.00e+00	6.587	1	1	10
GO:0035413	positive regulation of catenin import into nucleus	1.04e-02	1.00e+00	6.587	1	2	10
GO:0034260	negative regulation of GTPase activity	1.04e-02	1.00e+00	6.587	1	2	10
GO:0006974	cellular response to DNA damage stimulus	1.05e-02	1.00e+00	3.671	2	7	151
GO:0022408	negative regulation of cell-cell adhesion	1.14e-02	1.00e+00	6.450	1	1	11
GO:0070306	lens fiber cell differentiation	1.14e-02	1.00e+00	6.450	1	1	11
GO:0016050	vesicle organization	1.14e-02	1.00e+00	6.450	1	1	11
GO:0008354	germ cell migration	1.14e-02	1.00e+00	6.450	1	1	11
GO:0006895	Golgi to endosome transport	1.14e-02	1.00e+00	6.450	1	1	11
GO:0032740	positive regulation of interleukin-17 production	1.14e-02	1.00e+00	6.450	1	2	11
GO:0000398	mRNA splicing, via spliceosome	1.22e-02	1.00e+00	3.552	2	15	164
GO:2000249	regulation of actin cytoskeleton reorganization	1.24e-02	1.00e+00	6.324	1	1	12
GO:0043537	negative regulation of blood vessel endothelial cell migration	1.24e-02	1.00e+00	6.324	1	1	12
GO:0008143	poly(A) binding	1.24e-02	1.00e+00	6.324	1	2	12
GO:0060389	pathway-restricted SMAD protein phosphorylation	1.24e-02	1.00e+00	6.324	1	1	12
GO:0005838	proteasome regulatory particle	1.24e-02	1.00e+00	6.324	1	1	12
GO:0035198	miRNA binding	1.24e-02	1.00e+00	6.324	1	1	12
GO:0019048	modulation by virus of host morphology or physiology	1.24e-02	1.00e+00	6.324	1	1	12
GO:0071480	cellular response to gamma radiation	1.34e-02	1.00e+00	6.209	1	1	13
GO:0002028	regulation of sodium ion transport	1.34e-02	1.00e+00	6.209	1	1	13
GO:0048268	clathrin coat assembly	1.34e-02	1.00e+00	6.209	1	2	13
GO:0030214	hyaluronan catabolic process	1.34e-02	1.00e+00	6.209	1	1	13
GO:0050921	positive regulation of chemotaxis	1.34e-02	1.00e+00	6.209	1	1	13
GO:0031334	positive regulation of protein complex assembly	1.34e-02	1.00e+00	6.209	1	2	13
GO:0030234	enzyme regulator activity	1.34e-02	1.00e+00	6.209	1	2	13
GO:0003714	transcription corepressor activity	1.43e-02	1.00e+00	3.433	2	11	178
GO:0033280	response to vitamin D	1.45e-02	1.00e+00	6.102	1	1	14
GO:0030279	negative regulation of ossification	1.45e-02	1.00e+00	6.102	1	2	14
GO:0032270	positive regulation of cellular protein metabolic process	1.45e-02	1.00e+00	6.102	1	1	14
GO:0017016	Ras GTPase binding	1.45e-02	1.00e+00	6.102	1	1	14
GO:0000242	pericentriolar material	1.45e-02	1.00e+00	6.102	1	1	14
GO:0042307	positive regulation of protein import into nucleus	1.55e-02	1.00e+00	6.002	1	4	15
GO:0043011	myeloid dendritic cell differentiation	1.55e-02	1.00e+00	6.002	1	2	15
GO:0035066	positive regulation of histone acetylation	1.55e-02	1.00e+00	6.002	1	1	15
GO:0032456	endocytic recycling	1.55e-02	1.00e+00	6.002	1	1	15
GO:0043981	histone H4-K5 acetylation	1.55e-02	1.00e+00	6.002	1	5	15
GO:0001824	blastocyst development	1.55e-02	1.00e+00	6.002	1	2	15
GO:0043982	histone H4-K8 acetylation	1.55e-02	1.00e+00	6.002	1	5	15
GO:0007173	epidermal growth factor receptor signaling pathway	1.60e-02	1.00e+00	3.347	2	5	189
GO:0042176	regulation of protein catabolic process	1.65e-02	1.00e+00	5.909	1	2	16
GO:0048535	lymph node development	1.65e-02	1.00e+00	5.909	1	1	16
GO:0006796	phosphate-containing compound metabolic process	1.75e-02	1.00e+00	5.822	1	1	17
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1.75e-02	1.00e+00	5.822	1	1	17
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1.75e-02	1.00e+00	5.822	1	1	17
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.75e-02	1.00e+00	5.822	1	3	17
GO:0022624	proteasome accessory complex	1.75e-02	1.00e+00	5.822	1	1	17
GO:0035307	positive regulation of protein dephosphorylation	1.75e-02	1.00e+00	5.822	1	1	17
GO:0006754	ATP biosynthetic process	1.86e-02	1.00e+00	5.739	1	2	18
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	1.86e-02	1.00e+00	5.739	1	1	18
GO:0071158	positive regulation of cell cycle arrest	1.96e-02	1.00e+00	5.661	1	2	19
GO:0043984	histone H4-K16 acetylation	1.96e-02	1.00e+00	5.661	1	5	19
GO:0044822	poly(A) RNA binding	2.03e-02	1.00e+00	1.865	4	50	1056
GO:0071549	cellular response to dexamethasone stimulus	2.06e-02	1.00e+00	5.587	1	3	20
GO:0045930	negative regulation of mitotic cell cycle	2.06e-02	1.00e+00	5.587	1	1	20
GO:0032007	negative regulation of TOR signaling	2.06e-02	1.00e+00	5.587	1	1	20
GO:0008156	negative regulation of DNA replication	2.06e-02	1.00e+00	5.587	1	1	20
GO:0032757	positive regulation of interleukin-8 production	2.06e-02	1.00e+00	5.587	1	1	20
GO:0007492	endoderm development	2.16e-02	1.00e+00	5.517	1	2	21
GO:0010575	positive regulation vascular endothelial growth factor production	2.16e-02	1.00e+00	5.517	1	1	21
GO:0032967	positive regulation of collagen biosynthetic process	2.16e-02	1.00e+00	5.517	1	3	21
GO:0043029	T cell homeostasis	2.16e-02	1.00e+00	5.517	1	1	21
GO:0000123	histone acetyltransferase complex	2.16e-02	1.00e+00	5.517	1	6	21
GO:0031593	polyubiquitin binding	2.26e-02	1.00e+00	5.450	1	1	22
GO:0003823	antigen binding	2.26e-02	1.00e+00	5.450	1	2	22
GO:0005720	nuclear heterochromatin	2.26e-02	1.00e+00	5.450	1	2	22
GO:0060170	ciliary membrane	2.26e-02	1.00e+00	5.450	1	1	22
GO:0010508	positive regulation of autophagy	2.26e-02	1.00e+00	5.450	1	2	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.26e-02	1.00e+00	5.450	1	2	22
GO:0008380	RNA splicing	2.28e-02	1.00e+00	3.076	2	22	228
GO:0071346	cellular response to interferon-gamma	2.37e-02	1.00e+00	5.386	1	1	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.37e-02	1.00e+00	5.386	1	1	23
GO:0000060	protein import into nucleus, translocation	2.47e-02	1.00e+00	5.324	1	1	24
GO:0008134	transcription factor binding	2.55e-02	1.00e+00	2.990	2	18	242
GO:0006611	protein export from nucleus	2.57e-02	1.00e+00	5.265	1	3	25
GO:0010718	positive regulation of epithelial to mesenchymal transition	2.57e-02	1.00e+00	5.265	1	4	25
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	2.57e-02	1.00e+00	5.265	1	3	25
GO:0007339	binding of sperm to zona pellucida	2.57e-02	1.00e+00	5.265	1	2	25
GO:0035329	hippo signaling	2.67e-02	1.00e+00	5.209	1	5	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.67e-02	1.00e+00	5.209	1	3	26
GO:0051209	release of sequestered calcium ion into cytosol	2.67e-02	1.00e+00	5.209	1	1	26
GO:0048565	digestive tract development	2.67e-02	1.00e+00	5.209	1	2	26
GO:0071339	MLL1 complex	2.77e-02	1.00e+00	5.154	1	6	27
GO:0009314	response to radiation	2.77e-02	1.00e+00	5.154	1	1	27
GO:0050714	positive regulation of protein secretion	2.87e-02	1.00e+00	5.102	1	3	28
GO:0010467	gene expression	2.98e-02	1.00e+00	2.108	3	45	669
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.98e-02	1.00e+00	5.051	1	2	29
GO:0030501	positive regulation of bone mineralization	2.98e-02	1.00e+00	5.051	1	1	29
GO:0042130	negative regulation of T cell proliferation	3.08e-02	1.00e+00	5.002	1	1	30
GO:0060325	face morphogenesis	3.18e-02	1.00e+00	4.955	1	1	31
GO:0042594	response to starvation	3.18e-02	1.00e+00	4.955	1	4	31
GO:0007093	mitotic cell cycle checkpoint	3.18e-02	1.00e+00	4.955	1	1	31
GO:0005829	cytosol	3.24e-02	1.00e+00	1.209	6	86	2496
GO:0003677	DNA binding	3.25e-02	1.00e+00	1.659	4	49	1218
GO:0006954	inflammatory response	3.27e-02	1.00e+00	2.795	2	6	277
GO:0032570	response to progesterone	3.28e-02	1.00e+00	4.909	1	1	32
GO:0043491	protein kinase B signaling	3.28e-02	1.00e+00	4.909	1	2	32
GO:0002062	chondrocyte differentiation	3.28e-02	1.00e+00	4.909	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	3.28e-02	1.00e+00	4.909	1	2	32
GO:0001837	epithelial to mesenchymal transition	3.38e-02	1.00e+00	4.865	1	2	33
GO:0045599	negative regulation of fat cell differentiation	3.58e-02	1.00e+00	4.780	1	2	35
GO:0042552	myelination	3.58e-02	1.00e+00	4.780	1	4	35
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.68e-02	1.00e+00	4.739	1	2	36
GO:0001933	negative regulation of protein phosphorylation	3.68e-02	1.00e+00	4.739	1	2	36
GO:0071560	cellular response to transforming growth factor beta stimulus	3.68e-02	1.00e+00	4.739	1	3	36
GO:0051084	'de novo' posttranslational protein folding	3.78e-02	1.00e+00	4.700	1	5	37
GO:0048839	inner ear development	3.78e-02	1.00e+00	4.700	1	1	37
GO:0005902	microvillus	3.88e-02	1.00e+00	4.661	1	3	38
GO:0001657	ureteric bud development	3.88e-02	1.00e+00	4.661	1	2	38
GO:0097191	extrinsic apoptotic signaling pathway	3.88e-02	1.00e+00	4.661	1	1	38
GO:0071407	cellular response to organic cyclic compound	3.88e-02	1.00e+00	4.661	1	3	38
GO:0045786	negative regulation of cell cycle	3.98e-02	1.00e+00	4.624	1	3	39
GO:0035019	somatic stem cell maintenance	4.08e-02	1.00e+00	4.587	1	6	40
GO:0017148	negative regulation of translation	4.08e-02	1.00e+00	4.587	1	2	40
GO:0030136	clathrin-coated vesicle	4.28e-02	1.00e+00	4.517	1	5	42
GO:0071230	cellular response to amino acid stimulus	4.28e-02	1.00e+00	4.517	1	1	42
GO:0008283	cell proliferation	4.45e-02	1.00e+00	2.552	2	14	328
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.53e-02	1.00e+00	1.870	3	41	789
GO:0044297	cell body	4.68e-02	1.00e+00	4.386	1	2	46
GO:0043525	positive regulation of neuron apoptotic process	4.68e-02	1.00e+00	4.386	1	4	46
GO:0043406	positive regulation of MAP kinase activity	4.68e-02	1.00e+00	4.386	1	2	46
GO:0003723	RNA binding	4.80e-02	1.00e+00	2.491	2	18	342
GO:0005070	SH3/SH2 adaptor activity	4.88e-02	1.00e+00	4.324	1	2	48
GO:0031093	platelet alpha granule lumen	4.88e-02	1.00e+00	4.324	1	2	48
GO:0043565	sequence-specific DNA binding	4.90e-02	1.00e+00	2.475	2	11	346
GO:0001669	acrosomal vesicle	4.98e-02	1.00e+00	4.294	1	2	49
GO:0016049	cell growth	4.98e-02	1.00e+00	4.294	1	3	49
GO:0006521	regulation of cellular amino acid metabolic process	5.08e-02	1.00e+00	4.265	1	1	50
GO:0006986	response to unfolded protein	5.08e-02	1.00e+00	4.265	1	4	50
GO:0031100	organ regeneration	5.08e-02	1.00e+00	4.265	1	1	50
GO:0001948	glycoprotein binding	5.08e-02	1.00e+00	4.265	1	2	50
GO:0008285	negative regulation of cell proliferation	5.08e-02	1.00e+00	2.446	2	10	353
GO:0030334	regulation of cell migration	5.08e-02	1.00e+00	4.265	1	5	50
GO:0034976	response to endoplasmic reticulum stress	5.18e-02	1.00e+00	4.237	1	2	51
GO:0045454	cell redox homeostasis	5.18e-02	1.00e+00	4.237	1	1	51
GO:0050680	negative regulation of epithelial cell proliferation	5.18e-02	1.00e+00	4.237	1	2	51
GO:0045216	cell-cell junction organization	5.47e-02	1.00e+00	4.154	1	2	54
GO:0002244	hematopoietic progenitor cell differentiation	5.47e-02	1.00e+00	4.154	1	1	54
GO:0050679	positive regulation of epithelial cell proliferation	5.47e-02	1.00e+00	4.154	1	2	54
GO:0009967	positive regulation of signal transduction	5.67e-02	1.00e+00	4.102	1	1	56
GO:0046982	protein heterodimerization activity	5.80e-02	1.00e+00	2.339	2	8	380
GO:0000502	proteasome complex	5.87e-02	1.00e+00	4.051	1	3	58
GO:0033138	positive regulation of peptidyl-serine phosphorylation	5.97e-02	1.00e+00	4.027	1	2	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.97e-02	1.00e+00	4.027	1	6	59
GO:0005089	Rho guanyl-nucleotide exchange factor activity	5.97e-02	1.00e+00	4.027	1	1	59
GO:0005882	intermediate filament	6.16e-02	1.00e+00	3.978	1	2	61
GO:0006987	activation of signaling protein activity involved in unfolded protein response	6.16e-02	1.00e+00	3.978	1	2	61
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	6.16e-02	1.00e+00	3.978	1	2	61
GO:0009986	cell surface	6.41e-02	1.00e+00	2.258	2	9	402
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.46e-02	1.00e+00	3.909	1	1	64
GO:0009749	response to glucose	6.46e-02	1.00e+00	3.909	1	7	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.55e-02	1.00e+00	3.887	1	2	65
GO:0045892	negative regulation of transcription, DNA-templated	6.72e-02	1.00e+00	2.219	2	24	413
GO:0010468	regulation of gene expression	6.85e-02	1.00e+00	3.822	1	2	68
GO:0006366	transcription from RNA polymerase II promoter	6.89e-02	1.00e+00	2.198	2	30	419
GO:0050790	regulation of catalytic activity	6.94e-02	1.00e+00	3.801	1	1	69
GO:0005737	cytoplasm	6.98e-02	1.00e+00	0.837	7	124	3767
GO:0006874	cellular calcium ion homeostasis	7.04e-02	1.00e+00	3.780	1	2	70
GO:0051897	positive regulation of protein kinase B signaling	7.04e-02	1.00e+00	3.780	1	2	70
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.04e-02	1.00e+00	3.780	1	2	70
GO:0032355	response to estradiol	7.14e-02	1.00e+00	3.759	1	3	71
GO:0000165	MAPK cascade	7.24e-02	1.00e+00	3.739	1	2	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	7.24e-02	1.00e+00	3.739	1	1	72
GO:0005796	Golgi lumen	7.24e-02	1.00e+00	3.739	1	3	72
GO:0002020	protease binding	7.43e-02	1.00e+00	3.700	1	6	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	7.43e-02	1.00e+00	3.700	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.43e-02	1.00e+00	3.700	1	2	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.53e-02	1.00e+00	3.680	1	1	75
GO:0031901	early endosome membrane	7.53e-02	1.00e+00	3.680	1	1	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.53e-02	1.00e+00	3.680	1	1	75
GO:0010629	negative regulation of gene expression	7.72e-02	1.00e+00	3.642	1	4	77
GO:0007565	female pregnancy	7.82e-02	1.00e+00	3.624	1	2	78
GO:0030968	endoplasmic reticulum unfolded protein response	7.91e-02	1.00e+00	3.605	1	2	79
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	7.91e-02	1.00e+00	3.605	1	2	79
GO:0002576	platelet degranulation	8.20e-02	1.00e+00	3.552	1	2	82
GO:0032321	positive regulation of Rho GTPase activity	8.20e-02	1.00e+00	3.552	1	1	82
GO:0009653	anatomical structure morphogenesis	8.30e-02	1.00e+00	3.534	1	2	83
GO:0006464	cellular protein modification process	8.39e-02	1.00e+00	3.517	1	4	84
GO:0044267	cellular protein metabolic process	8.54e-02	1.00e+00	2.020	2	20	474
GO:0047485	protein N-terminus binding	8.58e-02	1.00e+00	3.483	1	3	86
GO:0090090	negative regulation of canonical Wnt signaling pathway	8.58e-02	1.00e+00	3.483	1	8	86
GO:0045893	positive regulation of transcription, DNA-templated	8.66e-02	1.00e+00	2.008	2	24	478
GO:0016020	membrane	8.80e-02	1.00e+00	1.194	4	46	1681
GO:0042802	identical protein binding	8.85e-02	1.00e+00	1.990	2	19	484
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	9.16e-02	1.00e+00	3.386	1	1	92
GO:0051082	unfolded protein binding	9.25e-02	1.00e+00	3.370	1	7	93
GO:0005770	late endosome	9.25e-02	1.00e+00	3.370	1	2	93
GO:0001934	positive regulation of protein phosphorylation	1.03e-01	1.00e+00	3.209	1	5	104
GO:0005509	calcium ion binding	1.04e-01	1.00e+00	1.857	2	11	531
GO:0016032	viral process	1.05e-01	1.00e+00	1.848	2	26	534
GO:0072562	blood microparticle	1.09e-01	1.00e+00	3.115	1	3	111
GO:0017124	SH3 domain binding	1.11e-01	1.00e+00	3.089	1	1	113
GO:0019058	viral life cycle	1.13e-01	1.00e+00	3.064	1	1	115
GO:0000209	protein polyubiquitination	1.14e-01	1.00e+00	3.051	1	3	116
GO:0007568	aging	1.15e-01	1.00e+00	3.039	1	2	117
GO:0006325	chromatin organization	1.16e-01	1.00e+00	3.027	1	12	118
GO:0006260	DNA replication	1.19e-01	1.00e+00	2.990	1	3	121
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.22e-01	1.00e+00	2.955	1	5	124
GO:0030335	positive regulation of cell migration	1.24e-01	1.00e+00	2.921	1	5	127
GO:0007179	transforming growth factor beta receptor signaling pathway	1.25e-01	1.00e+00	2.909	1	11	128
GO:0016055	Wnt signaling pathway	1.34e-01	1.00e+00	2.801	1	4	138
GO:0005125	cytokine activity	1.34e-01	1.00e+00	2.801	1	2	138
GO:0008083	growth factor activity	1.37e-01	1.00e+00	2.770	1	3	141
GO:0006457	protein folding	1.39e-01	1.00e+00	2.749	1	7	143
GO:0010628	positive regulation of gene expression	1.42e-01	1.00e+00	2.719	1	7	146
GO:0001666	response to hypoxia	1.44e-01	1.00e+00	2.690	1	7	149
GO:0000082	G1/S transition of mitotic cell cycle	1.44e-01	1.00e+00	2.690	1	3	149
GO:0005198	structural molecule activity	1.45e-01	1.00e+00	2.680	1	3	150
GO:0042981	regulation of apoptotic process	1.45e-01	1.00e+00	2.680	1	4	150
GO:0005578	proteinaceous extracellular matrix	1.54e-01	1.00e+00	2.587	1	4	160
GO:0030424	axon	1.59e-01	1.00e+00	2.534	1	4	166
GO:0003700	sequence-specific DNA binding transcription factor activity	1.63e-01	1.00e+00	1.460	2	39	699
GO:0034641	cellular nitrogen compound metabolic process	1.64e-01	1.00e+00	2.491	1	2	171
GO:0005667	transcription factor complex	1.67e-01	1.00e+00	2.458	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.70e-01	1.00e+00	2.433	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.75e-01	1.00e+00	2.386	1	22	184
GO:0030168	platelet activation	1.93e-01	1.00e+00	2.230	1	6	205
GO:0016071	mRNA metabolic process	2.09e-01	1.00e+00	2.108	1	8	223
GO:0003713	transcription coactivator activity	2.20e-01	1.00e+00	2.020	1	24	237
GO:0043025	neuronal cell body	2.27e-01	1.00e+00	1.973	1	9	245
GO:0016070	RNA metabolic process	2.28e-01	1.00e+00	1.961	1	8	247
GO:0005874	microtubule	2.30e-01	1.00e+00	1.949	1	7	249
GO:0070062	extracellular vesicular exosome	2.31e-01	1.00e+00	0.680	4	57	2400
GO:0000166	nucleotide binding	2.38e-01	1.00e+00	1.892	1	13	259
GO:0005730	nucleolus	2.39e-01	1.00e+00	0.814	3	66	1641
GO:0043065	positive regulation of apoptotic process	2.45e-01	1.00e+00	1.843	1	7	268
GO:0019899	enzyme binding	2.53e-01	1.00e+00	1.795	1	9	277
GO:0030198	extracellular matrix organization	2.57e-01	1.00e+00	1.765	1	6	283
GO:0042493	response to drug	2.58e-01	1.00e+00	1.759	1	6	284
GO:0005615	extracellular space	2.62e-01	1.00e+00	1.007	2	20	957
GO:0043231	intracellular membrane-bounded organelle	2.84e-01	1.00e+00	1.596	1	6	318
GO:0005813	centrosome	2.90e-01	1.00e+00	1.560	1	7	326
GO:0015031	protein transport	3.02e-01	1.00e+00	1.496	1	11	341
GO:0008284	positive regulation of cell proliferation	3.32e-01	1.00e+00	1.332	1	10	382
GO:0000278	mitotic cell cycle	3.38e-01	1.00e+00	1.298	1	15	391
GO:0043066	negative regulation of apoptotic process	3.61e-01	1.00e+00	1.181	1	16	424
GO:0007596	blood coagulation	3.82e-01	1.00e+00	1.079	1	11	455
GO:0006468	protein phosphorylation	3.85e-01	1.00e+00	1.064	1	10	460
GO:0005524	ATP binding	3.97e-01	1.00e+00	0.567	2	31	1298
GO:0006915	apoptotic process	4.45e-01	1.00e+00	0.793	1	12	555
GO:0005783	endoplasmic reticulum	4.46e-01	1.00e+00	0.790	1	13	556
GO:0006351	transcription, DNA-templated	4.52e-01	1.00e+00	0.411	2	57	1446
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.54e-01	1.00e+00	0.754	1	37	570
GO:0042803	protein homodimerization activity	4.69e-01	1.00e+00	0.692	1	19	595
GO:0005794	Golgi apparatus	4.77e-01	1.00e+00	0.657	1	9	610
GO:0005576	extracellular region	6.37e-01	1.00e+00	0.030	1	13	942
GO:0044281	small molecule metabolic process	7.32e-01	1.00e+00	-0.333	1	20	1211
GO:0005886	plasma membrane	7.79e-01	1.00e+00	-0.425	2	49	2582

chia-Fav

int-snw-3883

Statistics

Genes (15)

Interactions (17)

Related GO terms (342)