int-snw-10980

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.797	4.21e-15	7.56e-04	4.65e-03

chia-screen-data-Fav-int-snw-10980 subnetwork

Genes (12)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
EP300	2033	22	-2.274	3.120	415	Yes	Yes
COPS2	9318	2	-2.531	3.043	46	Yes	-
COPS4	51138	3	-3.198	3.043	47	Yes	Yes
COPS3	8533	1	-1.873	2.797	39	-	-
NOD2	64127	1	-1.921	2.797	26	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
HMOX2	3163	1	-2.116	2.797	36	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
[ COPS6 ]	10980	1	-1.765	2.797	139	-	-
GPS1	2873	3	-3.621	3.043	26	Yes	Yes
KLHL8	57563	1	-1.993	2.797	5	-	-

Interactions (18)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
EP300	2033	HNRNPU	3192	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vitro, in vivo
GPS1	2873	COPS4	51138	pp	--	int.Intact: MI:0915(physical association); int.I2D: BIND, IntAct, MGI
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
COPS2	9318	COPS6	10980	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BIND, BioGrid, HPRD, IntAct, MGI; int.HPRD: in vitro
COPS6	10980	KLHL8	57563	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct
COPS3	8533	COPS6	10980	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, BIND, HPRD, IntAct, BCI, INNATEDB, MGI; int.HPRD: in vitro; int.DIP: MI:0915(physical association)
COPS6	10980	COPS4	51138	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Fly, BIND_Fly, FlyLow, HPRD, IntAct, IntAct_Fly, BIND, MGI, MINT_Fly; int.HPRD: in vitro
COPS2	9318	COPS4	51138	pp	--	int.I2D: BIND, HPRD, MGI; int.HPRD: in vitro, in vivo
GPS1	2873	COPS2	9318	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Worm, MGI, MINT_Worm, BioGrid_Worm, BIND, BIND_Worm, CORE_1, HPRD, IntAct, INNATEDB; int.HPRD: in vitro, yeast 2-hybrid
COPS6	10980	NOD2	64127	pp	--	int.I2D: INNATEDB
COPS3	8533	COPS4	51138	pp	--	int.I2D: BIND, HPRD, BioGrid, INNATEDB, MGI; int.HPRD: in vitro, in vivo; int.DIP: MI:0915(physical association)
GPS1	2873	COPS3	8533	pp	--	int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, INNATEDB, BioGrid, MGI; int.HPRD: in vitro, yeast 2-hybrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
EP300	2033	YAP1	10413	pp	--	int.I2D: BioGrid
GPS1	2873	COPS6	10980	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MGI; int.HPRD: in vitro
COPS3	8533	COPS2	9318	pp	--	int.I2D: BioGrid, BCI, HPRD, INNATEDB, MGI; int.HPRD: in vitro; int.DIP: MI:0915(physical association)
EP300	2033	COPS6	10980	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, IntAct, StelzlMedium; int.HPRD: yeast 2-hybrid
HMOX2	3163	COPS6	10980	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, MINT, StelzlMedium, IntAct; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid

Related GO terms (272)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010388	cullin deneddylation	1.92e-14	2.76e-10	9.383	5	5	9
GO:0008180	COP9 signalosome	9.85e-14	1.42e-09	7.729	6	7	34
GO:0005515	protein binding	4.97e-04	1.00e+00	1.134	11	198	6024
GO:0007254	JNK cascade	7.30e-04	1.00e+00	5.616	2	2	49
GO:0002367	cytokine production involved in immune response	8.32e-04	1.00e+00	10.231	1	1	1
GO:1901985	positive regulation of protein acetylation	8.32e-04	1.00e+00	10.231	1	1	1
GO:0032498	detection of muramyl dipeptide	8.32e-04	1.00e+00	10.231	1	1	1
GO:0035419	activation of MAPK activity involved in innate immune response	8.32e-04	1.00e+00	10.231	1	1	1
GO:0043969	histone H2B acetylation	8.32e-04	1.00e+00	10.231	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	8.32e-04	1.00e+00	10.231	1	1	1
GO:0032500	muramyl dipeptide binding	8.32e-04	1.00e+00	10.231	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	8.32e-04	1.00e+00	10.231	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	8.32e-04	1.00e+00	10.231	1	1	1
GO:0002710	negative regulation of T cell mediated immunity	8.32e-04	1.00e+00	10.231	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	8.32e-04	1.00e+00	10.231	1	1	1
GO:0060177	regulation of angiotensin metabolic process	8.32e-04	1.00e+00	10.231	1	1	1
GO:0071608	macrophage inflammatory protein-1 alpha production	8.32e-04	1.00e+00	10.231	1	1	1
GO:0002732	positive regulation of dendritic cell cytokine production	8.32e-04	1.00e+00	10.231	1	1	1
GO:2000629	negative regulation of miRNA metabolic process	8.32e-04	1.00e+00	10.231	1	1	1
GO:2000363	positive regulation of prostaglandin-E synthase activity	8.32e-04	1.00e+00	10.231	1	1	1
GO:0032701	negative regulation of interleukin-18 production	8.32e-04	1.00e+00	10.231	1	1	1
GO:0046645	positive regulation of gamma-delta T cell activation	8.32e-04	1.00e+00	10.231	1	1	1
GO:0060242	contact inhibition	1.66e-03	1.00e+00	9.231	1	1	2
GO:0009786	regulation of asymmetric cell division	1.66e-03	1.00e+00	9.231	1	1	2
GO:0090043	regulation of tubulin deacetylation	1.66e-03	1.00e+00	9.231	1	2	2
GO:0071389	cellular response to mineralocorticoid stimulus	1.66e-03	1.00e+00	9.231	1	1	2
GO:0006788	heme oxidation	1.66e-03	1.00e+00	9.231	1	2	2
GO:0014737	positive regulation of muscle atrophy	1.66e-03	1.00e+00	9.231	1	1	2
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	1.66e-03	1.00e+00	9.231	1	1	2
GO:0035984	cellular response to trichostatin A	1.66e-03	1.00e+00	9.231	1	1	2
GO:0004392	heme oxygenase (decyclizing) activity	1.66e-03	1.00e+00	9.231	1	2	2
GO:0090022	regulation of neutrophil chemotaxis	2.49e-03	1.00e+00	8.646	1	1	3
GO:0000338	protein deneddylation	2.49e-03	1.00e+00	8.646	1	1	3
GO:0018076	N-terminal peptidyl-lysine acetylation	2.49e-03	1.00e+00	8.646	1	1	3
GO:0071225	cellular response to muramyl dipeptide	2.49e-03	1.00e+00	8.646	1	1	3
GO:0060913	cardiac cell fate determination	2.49e-03	1.00e+00	8.646	1	1	3
GO:0010560	positive regulation of glycoprotein biosynthetic process	2.49e-03	1.00e+00	8.646	1	1	3
GO:0009595	detection of biotic stimulus	2.49e-03	1.00e+00	8.646	1	1	3
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	2.49e-03	1.00e+00	8.646	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.49e-03	1.00e+00	8.646	1	1	3
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	2.49e-03	1.00e+00	8.646	1	1	3
GO:0097157	pre-mRNA intronic binding	3.32e-03	1.00e+00	8.231	1	1	4
GO:0018393	internal peptidyl-lysine acetylation	3.32e-03	1.00e+00	8.231	1	1	4
GO:2000110	negative regulation of macrophage apoptotic process	3.32e-03	1.00e+00	8.231	1	1	4
GO:0071224	cellular response to peptidoglycan	3.32e-03	1.00e+00	8.231	1	1	4
GO:0050871	positive regulation of B cell activation	3.32e-03	1.00e+00	8.231	1	1	4
GO:0005737	cytoplasm	3.74e-03	1.00e+00	1.352	8	124	3767
GO:0001714	endodermal cell fate specification	4.15e-03	1.00e+00	7.909	1	1	5
GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	4.15e-03	1.00e+00	7.909	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.15e-03	1.00e+00	7.909	1	2	5
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	4.15e-03	1.00e+00	7.909	1	1	5
GO:0065004	protein-DNA complex assembly	4.15e-03	1.00e+00	7.909	1	1	5
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	4.15e-03	1.00e+00	7.909	1	1	5
GO:0002830	positive regulation of type 2 immune response	4.15e-03	1.00e+00	7.909	1	1	5
GO:0060298	positive regulation of sarcomere organization	4.15e-03	1.00e+00	7.909	1	1	5
GO:0032025	response to cobalt ion	4.15e-03	1.00e+00	7.909	1	1	5
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	4.98e-03	1.00e+00	7.646	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	4.98e-03	1.00e+00	7.646	1	3	6
GO:0042167	heme catabolic process	4.98e-03	1.00e+00	7.646	1	2	6
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	4.98e-03	1.00e+00	7.646	1	1	6
GO:0051353	positive regulation of oxidoreductase activity	5.81e-03	1.00e+00	7.424	1	1	7
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	5.81e-03	1.00e+00	7.424	1	1	7
GO:0032731	positive regulation of interleukin-1 beta production	5.81e-03	1.00e+00	7.424	1	1	7
GO:0006475	internal protein amino acid acetylation	5.81e-03	1.00e+00	7.424	1	1	7
GO:0001666	response to hypoxia	6.54e-03	1.00e+00	4.012	2	7	149
GO:0050700	CARD domain binding	6.64e-03	1.00e+00	7.231	1	1	8
GO:0035259	glucocorticoid receptor binding	7.47e-03	1.00e+00	7.061	1	1	9
GO:0045793	positive regulation of cell size	7.47e-03	1.00e+00	7.061	1	2	9
GO:0060765	regulation of androgen receptor signaling pathway	7.47e-03	1.00e+00	7.061	1	1	9
GO:0042834	peptidoglycan binding	7.47e-03	1.00e+00	7.061	1	1	9
GO:0032495	response to muramyl dipeptide	7.47e-03	1.00e+00	7.061	1	2	9
GO:0044212	transcription regulatory region DNA binding	8.24e-03	1.00e+00	3.839	2	17	168
GO:0032703	negative regulation of interleukin-2 production	8.29e-03	1.00e+00	6.909	1	1	10
GO:0035413	positive regulation of catenin import into nucleus	8.29e-03	1.00e+00	6.909	1	2	10
GO:0016407	acetyltransferase activity	8.29e-03	1.00e+00	6.909	1	2	10
GO:0005667	transcription factor complex	8.92e-03	1.00e+00	3.780	2	17	175
GO:0030277	maintenance of gastrointestinal epithelium	9.12e-03	1.00e+00	6.772	1	2	11
GO:0043923	positive regulation by host of viral transcription	9.12e-03	1.00e+00	6.772	1	1	11
GO:0032740	positive regulation of interleukin-17 production	9.12e-03	1.00e+00	6.772	1	2	11
GO:0033160	positive regulation of protein import into nucleus, translocation	9.12e-03	1.00e+00	6.772	1	3	11
GO:0042975	peroxisome proliferator activated receptor binding	9.12e-03	1.00e+00	6.772	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	9.12e-03	1.00e+00	6.772	1	4	11
GO:0003714	transcription corepressor activity	9.22e-03	1.00e+00	3.755	2	11	178
GO:0005654	nucleoplasm	9.57e-03	1.00e+00	2.152	4	64	1082
GO:0032874	positive regulation of stress-activated MAPK cascade	9.94e-03	1.00e+00	6.646	1	1	12
GO:0032695	negative regulation of interleukin-12 production	9.94e-03	1.00e+00	6.646	1	1	12
GO:0035198	miRNA binding	9.94e-03	1.00e+00	6.646	1	1	12
GO:0071480	cellular response to gamma radiation	1.08e-02	1.00e+00	6.531	1	1	13
GO:0009416	response to light stimulus	1.08e-02	1.00e+00	6.531	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.08e-02	1.00e+00	6.531	1	2	13
GO:0016746	transferase activity, transferring acyl groups	1.08e-02	1.00e+00	6.531	1	1	13
GO:0005095	GTPase inhibitor activity	1.08e-02	1.00e+00	6.531	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.08e-02	1.00e+00	6.531	1	2	13
GO:0016045	detection of bacterium	1.16e-02	1.00e+00	6.424	1	1	14
GO:0070542	response to fatty acid	1.16e-02	1.00e+00	6.424	1	1	14
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.16e-02	1.00e+00	6.424	1	1	14
GO:0032993	protein-DNA complex	1.16e-02	1.00e+00	6.424	1	2	14
GO:0001824	blastocyst development	1.24e-02	1.00e+00	6.324	1	2	15
GO:1990090	cellular response to nerve growth factor stimulus	1.24e-02	1.00e+00	6.324	1	1	15
GO:0002227	innate immune response in mucosa	1.32e-02	1.00e+00	6.231	1	2	16
GO:0005634	nucleus	1.33e-02	1.00e+00	1.077	8	159	4559
GO:0044130	negative regulation of growth of symbiont in host	1.41e-02	1.00e+00	6.144	1	1	17
GO:0050718	positive regulation of interleukin-1 beta secretion	1.49e-02	1.00e+00	6.061	1	1	18
GO:0045773	positive regulation of axon extension	1.49e-02	1.00e+00	6.061	1	1	18
GO:0033613	activating transcription factor binding	1.49e-02	1.00e+00	6.061	1	3	18
GO:0006778	porphyrin-containing compound metabolic process	1.49e-02	1.00e+00	6.061	1	2	18
GO:0032733	positive regulation of interleukin-10 production	1.57e-02	1.00e+00	5.983	1	2	19
GO:0035257	nuclear hormone receptor binding	1.57e-02	1.00e+00	5.983	1	1	19
GO:0003713	transcription coactivator activity	1.59e-02	1.00e+00	3.342	2	24	237
GO:0071549	cellular response to dexamethasone stimulus	1.65e-02	1.00e+00	5.909	1	3	20
GO:0010942	positive regulation of cell death	1.65e-02	1.00e+00	5.909	1	1	20
GO:0008134	transcription factor binding	1.66e-02	1.00e+00	3.312	2	18	242
GO:0045747	positive regulation of Notch signaling pathway	1.73e-02	1.00e+00	5.839	1	1	21
GO:0032967	positive regulation of collagen biosynthetic process	1.73e-02	1.00e+00	5.839	1	3	21
GO:0045862	positive regulation of proteolysis	1.73e-02	1.00e+00	5.839	1	2	21
GO:0000123	histone acetyltransferase complex	1.73e-02	1.00e+00	5.839	1	6	21
GO:0003823	antigen binding	1.82e-02	1.00e+00	5.772	1	2	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.82e-02	1.00e+00	5.772	1	2	22
GO:0050766	positive regulation of phagocytosis	1.90e-02	1.00e+00	5.708	1	1	23
GO:0031463	Cul3-RING ubiquitin ligase complex	1.90e-02	1.00e+00	5.708	1	1	23
GO:0032689	negative regulation of interferon-gamma production	1.98e-02	1.00e+00	5.646	1	1	24
GO:0043388	positive regulation of DNA binding	1.98e-02	1.00e+00	5.646	1	2	24
GO:0043425	bHLH transcription factor binding	1.98e-02	1.00e+00	5.646	1	1	24
GO:0043330	response to exogenous dsRNA	1.98e-02	1.00e+00	5.646	1	1	24
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	2.06e-02	1.00e+00	5.587	1	1	25
GO:0051059	NF-kappaB binding	2.06e-02	1.00e+00	5.587	1	3	25
GO:0032735	positive regulation of interleukin-12 production	2.06e-02	1.00e+00	5.587	1	2	25
GO:0035329	hippo signaling	2.14e-02	1.00e+00	5.531	1	5	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	2.14e-02	1.00e+00	5.531	1	1	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.14e-02	1.00e+00	5.531	1	3	26
GO:0048565	digestive tract development	2.14e-02	1.00e+00	5.531	1	2	26
GO:0032720	negative regulation of tumor necrosis factor production	2.22e-02	1.00e+00	5.476	1	2	27
GO:0000188	inactivation of MAPK activity	2.22e-02	1.00e+00	5.476	1	1	27
GO:0034612	response to tumor necrosis factor	2.22e-02	1.00e+00	5.476	1	2	27
GO:0043967	histone H4 acetylation	2.22e-02	1.00e+00	5.476	1	1	27
GO:0050714	positive regulation of protein secretion	2.31e-02	1.00e+00	5.424	1	3	28
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2.47e-02	1.00e+00	5.324	1	1	30
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.48e-02	1.00e+00	2.192	3	41	789
GO:0043491	protein kinase B signaling	2.63e-02	1.00e+00	5.231	1	2	32
GO:1903507	negative regulation of nucleic acid-templated transcription	2.63e-02	1.00e+00	5.231	1	2	32
GO:0001756	somitogenesis	2.71e-02	1.00e+00	5.187	1	1	33
GO:0071333	cellular response to glucose stimulus	2.71e-02	1.00e+00	5.187	1	1	33
GO:0008283	cell proliferation	2.93e-02	1.00e+00	2.874	2	14	328
GO:0001102	RNA polymerase II activating transcription factor binding	2.96e-02	1.00e+00	5.061	1	1	36
GO:0032755	positive regulation of interleukin-6 production	2.96e-02	1.00e+00	5.061	1	2	36
GO:0032760	positive regulation of tumor necrosis factor production	3.04e-02	1.00e+00	5.022	1	2	37
GO:0031490	chromatin DNA binding	3.12e-02	1.00e+00	4.983	1	2	38
GO:0071407	cellular response to organic cyclic compound	3.12e-02	1.00e+00	4.983	1	3	38
GO:0032092	positive regulation of protein binding	3.12e-02	1.00e+00	4.983	1	2	38
GO:0050681	androgen receptor binding	3.12e-02	1.00e+00	4.983	1	1	38
GO:0051259	protein oligomerization	3.20e-02	1.00e+00	4.946	1	2	39
GO:0046332	SMAD binding	3.28e-02	1.00e+00	4.909	1	2	40
GO:0071320	cellular response to cAMP	3.28e-02	1.00e+00	4.909	1	1	40
GO:0035019	somatic stem cell maintenance	3.28e-02	1.00e+00	4.909	1	6	40
GO:0007519	skeletal muscle tissue development	3.28e-02	1.00e+00	4.909	1	2	40
GO:0070301	cellular response to hydrogen peroxide	3.36e-02	1.00e+00	4.874	1	2	41
GO:0035914	skeletal muscle cell differentiation	3.36e-02	1.00e+00	4.874	1	2	41
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	3.52e-02	1.00e+00	4.805	1	1	43
GO:0004402	histone acetyltransferase activity	3.52e-02	1.00e+00	4.805	1	6	43
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3.60e-02	1.00e+00	4.772	1	4	44
GO:0045727	positive regulation of translation	3.60e-02	1.00e+00	4.772	1	2	44
GO:0043966	histone H3 acetylation	3.68e-02	1.00e+00	4.739	1	5	45
GO:0001047	core promoter binding	3.68e-02	1.00e+00	4.739	1	5	45
GO:0050727	regulation of inflammatory response	3.68e-02	1.00e+00	4.739	1	1	45
GO:0050830	defense response to Gram-positive bacterium	3.68e-02	1.00e+00	4.739	1	3	45
GO:0006952	defense response	3.84e-02	1.00e+00	4.677	1	2	47
GO:0005730	nucleolus	3.91e-02	1.00e+00	1.551	4	66	1641
GO:0035690	cellular response to drug	4.00e-02	1.00e+00	4.616	1	3	49
GO:0006879	cellular iron ion homeostasis	4.16e-02	1.00e+00	4.559	1	3	51
GO:0031398	positive regulation of protein ubiquitination	4.24e-02	1.00e+00	4.531	1	1	52
GO:0009611	response to wounding	4.24e-02	1.00e+00	4.531	1	5	52
GO:0009986	cell surface	4.25e-02	1.00e+00	2.580	2	9	402
GO:0007623	circadian rhythm	4.32e-02	1.00e+00	4.503	1	1	53
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	4.40e-02	1.00e+00	4.476	1	3	54
GO:0051403	stress-activated MAPK cascade	4.40e-02	1.00e+00	4.476	1	2	54
GO:0050679	positive regulation of epithelial cell proliferation	4.40e-02	1.00e+00	4.476	1	2	54
GO:0051592	response to calcium ion	4.48e-02	1.00e+00	4.450	1	1	55
GO:0002039	p53 binding	4.48e-02	1.00e+00	4.450	1	4	55
GO:0046330	positive regulation of JNK cascade	4.48e-02	1.00e+00	4.450	1	2	55
GO:0071300	cellular response to retinoic acid	4.48e-02	1.00e+00	4.450	1	1	55
GO:0006355	regulation of transcription, DNA-templated	4.53e-02	1.00e+00	1.855	3	43	997
GO:0043627	response to estrogen	4.56e-02	1.00e+00	4.424	1	5	56
GO:0006366	transcription from RNA polymerase II promoter	4.58e-02	1.00e+00	2.520	2	30	419
GO:0006396	RNA processing	4.80e-02	1.00e+00	4.348	1	5	59
GO:0042742	defense response to bacterium	4.88e-02	1.00e+00	4.324	1	5	60
GO:0008013	beta-catenin binding	4.88e-02	1.00e+00	4.324	1	9	60
GO:0032481	positive regulation of type I interferon production	4.96e-02	1.00e+00	4.300	1	6	61
GO:0032088	negative regulation of NF-kappaB transcription factor activity	5.12e-02	1.00e+00	4.254	1	3	63
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.12e-02	1.00e+00	4.254	1	4	63
GO:0034166	toll-like receptor 10 signaling pathway	5.28e-02	1.00e+00	4.209	1	4	65
GO:0034146	toll-like receptor 5 signaling pathway	5.28e-02	1.00e+00	4.209	1	4	65
GO:0010468	regulation of gene expression	5.52e-02	1.00e+00	4.144	1	2	68
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	5.75e-02	1.00e+00	4.081	1	4	71
GO:0007584	response to nutrient	5.75e-02	1.00e+00	4.081	1	3	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	5.75e-02	1.00e+00	4.081	1	4	71
GO:0034162	toll-like receptor 9 signaling pathway	5.83e-02	1.00e+00	4.061	1	4	72
GO:0030324	lung development	5.83e-02	1.00e+00	4.061	1	1	72
GO:0008021	synaptic vesicle	5.91e-02	1.00e+00	4.041	1	2	73
GO:0034134	toll-like receptor 2 signaling pathway	5.91e-02	1.00e+00	4.041	1	4	73
GO:0000785	chromatin	5.91e-02	1.00e+00	4.041	1	6	73
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	5.99e-02	1.00e+00	4.022	1	4	74
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	6.07e-02	1.00e+00	4.002	1	2	75
GO:0030182	neuron differentiation	6.15e-02	1.00e+00	3.983	1	1	76
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	6.15e-02	1.00e+00	3.983	1	3	76
GO:0001889	liver development	6.22e-02	1.00e+00	3.964	1	3	77
GO:0071013	catalytic step 2 spliceosome	6.30e-02	1.00e+00	3.946	1	7	78
GO:0002756	MyD88-independent toll-like receptor signaling pathway	6.30e-02	1.00e+00	3.946	1	3	78
GO:0034138	toll-like receptor 3 signaling pathway	6.38e-02	1.00e+00	3.927	1	3	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	6.46e-02	1.00e+00	3.909	1	5	80
GO:0009653	anatomical structure morphogenesis	6.69e-02	1.00e+00	3.856	1	2	83
GO:0009887	organ morphogenesis	6.93e-02	1.00e+00	3.805	1	5	86
GO:0045471	response to ethanol	6.93e-02	1.00e+00	3.805	1	3	86
GO:0016032	viral process	7.07e-02	1.00e+00	2.170	2	26	534
GO:0000187	activation of MAPK activity	7.24e-02	1.00e+00	3.739	1	3	90
GO:0001649	osteoblast differentiation	7.39e-02	1.00e+00	3.708	1	5	92
GO:0071456	cellular response to hypoxia	7.39e-02	1.00e+00	3.708	1	3	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	7.39e-02	1.00e+00	3.708	1	7	92
GO:0003677	DNA binding	7.43e-02	1.00e+00	1.566	3	49	1218
GO:0034142	toll-like receptor 4 signaling pathway	7.70e-02	1.00e+00	3.646	1	4	96
GO:0051726	regulation of cell cycle	7.78e-02	1.00e+00	3.631	1	5	97
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	7.92e-02	1.00e+00	2.076	2	37	570
GO:0001934	positive regulation of protein phosphorylation	8.32e-02	1.00e+00	3.531	1	5	104
GO:0070374	positive regulation of ERK1 and ERK2 cascade	8.47e-02	1.00e+00	3.503	1	1	106
GO:0045087	innate immune response	8.56e-02	1.00e+00	2.012	2	15	596
GO:0002224	toll-like receptor signaling pathway	8.70e-02	1.00e+00	3.463	1	4	109
GO:0030529	ribonucleoprotein complex	8.93e-02	1.00e+00	3.424	1	5	112
GO:0006325	chromatin organization	9.39e-02	1.00e+00	3.348	1	12	118
GO:0007219	Notch signaling pathway	9.54e-02	1.00e+00	3.324	1	5	120
GO:0032496	response to lipopolysaccharide	9.62e-02	1.00e+00	3.312	1	4	121
GO:0051092	positive regulation of NF-kappaB transcription factor activity	9.85e-02	1.00e+00	3.277	1	5	124
GO:0031982	vesicle	1.04e-01	1.00e+00	3.198	1	3	131
GO:0010467	gene expression	1.04e-01	1.00e+00	1.845	2	45	669
GO:0000086	G2/M transition of mitotic cell cycle	1.08e-01	1.00e+00	3.144	1	4	136
GO:0007507	heart development	1.10e-01	1.00e+00	3.112	1	7	139
GO:0003700	sequence-specific DNA binding transcription factor activity	1.12e-01	1.00e+00	1.782	2	39	699
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.14e-01	1.00e+00	3.051	1	4	145
GO:0006974	cellular response to DNA damage stimulus	1.19e-01	1.00e+00	2.993	1	7	151
GO:0000398	mRNA splicing, via spliceosome	1.28e-01	1.00e+00	2.874	1	15	164
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.29e-01	1.00e+00	2.865	1	12	165
GO:0007049	cell cycle	1.36e-01	1.00e+00	2.788	1	6	174
GO:0031625	ubiquitin protein ligase binding	1.38e-01	1.00e+00	2.755	1	5	178
GO:0032403	protein complex binding	1.42e-01	1.00e+00	2.715	1	6	183
GO:0006367	transcription initiation from RNA polymerase II promoter	1.43e-01	1.00e+00	2.708	1	22	184
GO:0001701	in utero embryonic development	1.55e-01	1.00e+00	2.580	1	8	201
GO:0004871	signal transducer activity	1.60e-01	1.00e+00	2.531	1	4	208
GO:0007165	signal transduction	1.72e-01	1.00e+00	1.406	2	13	907
GO:0008380	RNA splicing	1.74e-01	1.00e+00	2.398	1	22	228
GO:0007399	nervous system development	1.76e-01	1.00e+00	2.379	1	6	231
GO:0019899	enzyme binding	2.08e-01	1.00e+00	2.117	1	9	277
GO:0005856	cytoskeleton	2.17e-01	1.00e+00	2.046	1	9	291
GO:0044822	poly(A) RNA binding	2.18e-01	1.00e+00	1.187	2	50	1056
GO:0016567	protein ubiquitination	2.20e-01	1.00e+00	2.027	1	4	295
GO:0043234	protein complex	2.20e-01	1.00e+00	2.027	1	11	295
GO:0035556	intracellular signal transduction	2.25e-01	1.00e+00	1.988	1	9	303
GO:0019901	protein kinase binding	2.34e-01	1.00e+00	1.923	1	18	317
GO:0003682	chromatin binding	2.41e-01	1.00e+00	1.878	1	19	327
GO:0030054	cell junction	2.46e-01	1.00e+00	1.839	1	5	336
GO:0003723	RNA binding	2.50e-01	1.00e+00	1.813	1	18	342
GO:0043565	sequence-specific DNA binding	2.53e-01	1.00e+00	1.796	1	11	346
GO:0000278	mitotic cell cycle	2.81e-01	1.00e+00	1.620	1	15	391
GO:0005524	ATP binding	2.95e-01	1.00e+00	0.889	2	31	1298
GO:0055085	transmembrane transport	3.08e-01	1.00e+00	1.466	1	8	435
GO:0005829	cytosol	3.45e-01	1.00e+00	0.531	3	86	2496
GO:0006915	apoptotic process	3.76e-01	1.00e+00	1.115	1	12	555
GO:0005789	endoplasmic reticulum membrane	3.84e-01	1.00e+00	1.076	1	9	570
GO:0016020	membrane	4.16e-01	1.00e+00	0.516	2	46	1681
GO:0008270	zinc ion binding	5.77e-01	1.00e+00	0.270	1	27	997
GO:0070062	extracellular vesicular exosome	6.18e-01	1.00e+00	0.002	2	57	2400
GO:0044281	small molecule metabolic process	6.51e-01	1.00e+00	-0.011	1	20	1211
GO:0005886	plasma membrane	6.61e-01	1.00e+00	-0.103	2	49	2582
GO:0046872	metal ion binding	6.80e-01	1.00e+00	-0.121	1	29	1307
GO:0006351	transcription, DNA-templated	7.19e-01	1.00e+00	-0.267	1	57	1446

chia-Fav

int-snw-10980

Statistics

Genes (12)

Interactions (18)

Related GO terms (272)