meta-int-snw-1455

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-1455 wolf-screen-ratio-mammosphere-adherent 0.994 6.85e-18 6.35e-04 1.46e-02 16 15
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-1994 wolf-screen-ratio-mammosphere-adherent 0.809 1.87e-06 4.21e-03 7.70e-03 6 6
reg-snw-1478 wolf-screen-ratio-mammosphere-adherent 0.940 8.80e-09 2.25e-04 5.65e-04 7 7
reg-snw-2237 wolf-screen-ratio-mammosphere-adherent 0.894 6.72e-08 6.99e-04 1.55e-03 9 8
reg-snw-5925 wolf-screen-ratio-mammosphere-adherent 0.802 2.42e-06 4.82e-03 8.69e-03 8 5
reg-snw-9134 wolf-screen-ratio-mammosphere-adherent 0.872 1.64e-07 1.14e-03 2.40e-03 8 7
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-1455 subnetwork

Genes (41)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree Transcription factor wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
CCNE2 9134 5-0.1640.872126TF--
PSMB1 5689 610.6880.901113-Yes-
PSMA3 5684 900.5330.815238-Yes-
PPCS 79717 31-0.5690.8022--Yes
DDX18 8886 250.6601.013215TFYes-
PSMA2 5683 1121.0931.106108-Yes-
RRM1 6240 150.5870.872117-Yes-
VARS 7407 860.5491.002204TFYes-
LPIN3 64900 8-0.6250.99439--Yes
TFRC 7037 310.7300.80217---
ADH5 128 160.6330.99443-Yes-
RPA2 6118 961.2501.15176-Yes-
CAD 790 910.8070.973400---
RB1 5925 31-0.1020.802351TF--
RSL24D1 51187 381.3001.02059-Yes-
CCNA2 890 540.5500.973246TFYes-
EIF2S2 8894 391.0750.940103-Yes-
EFTUD2 9343 930.8830.956108-Yes-
TUBG1 7283 980.9740.97391-Yes-
PSMD11 5717 1241.0951.106218TFYes-
RAN 5901 890.6320.899258-Yes-
FEN1 2237 100.0140.89489---
CSNK1G2 1455 8-0.0840.99490---
RBX1 9978 1151.1850.934148TFYes-
POLA1 5422 170.5930.894114TFYes-
PPIE 10450 310.5670.80241TF--
HNRNPC 3183 1081.8120.973181-Yes-
PSMB7 5695 1180.9820.93490-Yes-
TREX1 11277 51-0.0510.88291TFYes-
OGDH 4967 720.8470.802126-Yes-
POLE4 56655 630.1770.82856TF--
PSMB3 5691 640.6680.90119-Yes-
RPSA 3921 1201.3271.151152-Yes-
PGD 5226 891.2011.106152-Yes-
RUVBL1 8607 950.7200.973469TFYes-
ELAVL1 1994 30.5170.809215TFYes-
CLTC 1213 560.8841.138247-Yes-
CSTF2 1478 10-0.0500.94098TF-Yes
PSMB2 5690 1160.8770.956169-Yes-
ACTB 60 1341.1531.151610-Yes-
RUVBL2 10856 950.6930.956532TFYes-

Interactions (127)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
ADH5 128 DDX18 8886 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
FEN1 2237 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
RB1 5925 PPCS 79717 pd > reg.pazar.txt: no annot
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
RB1 5925 RPA2 6118 pd > reg.pazar.txt: no annot
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
CLTC 1213 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
ELAVL1 1994 PSMB2 5690 pd > reg.ITFP.txt: no annot
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PGD 5226 RB1 5925 pd < reg.pazar.txt: no annot
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
RBX1 9978 PPIE 10450 pd <> reg.ITFP.txt: no annot
CSNK1G2 1455 PSMA3 5684 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
ELAVL1 1994 RAN 5901 pd > reg.ITFP.txt: no annot
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
CLTC 1213 RUVBL1 8607 pp -- int.I2D: MINT_Worm, IntAct_Worm
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
FEN1 2237 PSMD11 5717 pd < reg.ITFP.txt: no annot
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
CSNK1G2 1455 DDX18 8886 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
CCNA2 890 RRM1 6240 pd > reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
OGDH 4967 RB1 5925 pd < reg.ITFP.txt: no annot
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMD11 5717 DDX18 8886 pp -- int.I2D: YeastLow
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
CSTF2 1478 FEN1 2237 pd > reg.ITFP.txt: no annot
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
RUVBL1 8607 DDX18 8886 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
ADH5 128 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
CSTF2 1478 EFTUD2 9343 pd > reg.ITFP.txt: no annot
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
OGDH 4967 DDX18 8886 pp -- int.I2D: YeastLow
CCNA2 890 RB1 5925 pp -- int.I2D: IntAct
CAD 790 LPIN3 64900 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
FEN1 2237 CCNE2 9134 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
FEN1 2237 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
ELAVL1 1994 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
ELAVL1 1994 FEN1 2237 pd > reg.ITFP.txt: no annot
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
CCNA2 890 FEN1 2237 pd > reg.ITFP.txt: no annot
CCNA2 890 FEN1 2237 pp -- int.I2D: BioGrid
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
DDX18 8886 RSL24D1 51187 pp -- int.I2D: YeastLow, BioGrid_Yeast
CCNA2 890 CCNE2 9134 pd <> reg.ITFP.txt: no annot
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PPIE 10450 pd < reg.ITFP.txt: no annot
ELAVL1 1994 DDX18 8886 pd <> reg.ITFP.txt: no annot
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
FEN1 2237 POLA1 5422 pd < reg.ITFP.txt: no annot
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
RB1 5925 TFRC 7037 pd > reg.ITFP.txt: no annot
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 RAN 5901 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
RRM1 6240 CCNE2 9134 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
RB1 5925 PPIE 10450 pd > reg.pazar.txt: no annot
POLA1 5422 RB1 5925 pp -- int.I2D: BCI, BioGrid, HPRD;
int.HPRD: in vitro, in vivo
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMD11 5717 RRM1 6240 pd > reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
PGD 5226 DDX18 8886 pp -- int.I2D: YeastLow
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
CSNK1G2 1455 LPIN3 64900 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (511)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005654nucleoplasm5.20e-178.49e-133.06423831095
GO:0000278mitotic cell cycle1.76e-142.87e-103.9071552398
GO:0000082G1/S transition of mitotic cell cycle6.80e-141.11e-094.8681133150
GO:0005839proteasome core complex3.11e-125.08e-087.05261118
GO:0004298threonine-type endopeptidase activity6.48e-121.06e-076.90061120
GO:0010467gene expression3.12e-115.10e-073.1581558669
GO:0006521regulation of cellular amino acid metabolic process3.40e-115.54e-075.80072150
GO:0000502proteasome complex1.01e-101.64e-065.58672258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.30e-103.76e-065.42272465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.30e-103.76e-065.42272265
GO:0016032viral process3.72e-106.07e-063.2611355540
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.93e-106.41e-065.31572470
GO:0005829cytosol4.45e-107.26e-061.899241252562
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent5.31e-108.67e-065.25472373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.86e-109.56e-065.23572474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I7.78e-101.27e-055.17772377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process9.35e-101.53e-055.14072579
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.21e-095.24e-054.89072394
GO:0016071mRNA metabolic process3.39e-095.52e-054.006934223
GO:0016070RNA metabolic process8.27e-091.35e-043.858934247
GO:0034641cellular nitrogen compound metabolic process1.15e-081.88e-044.169825177
GO:0000209protein polyubiquitination1.41e-082.29e-044.586721116
GO:0042981regulation of apoptotic process8.72e-081.42e-034.206726151
GO:0005515protein binding1.41e-072.30e-031.056321726127
GO:0044281small molecule metabolic process2.53e-074.12e-032.20515571295
GO:0070062extracellular vesicular exosome5.37e-078.76e-031.66220982516
GO:0005634nucleus1.65e-062.70e-021.155271314828
GO:0016020membrane2.08e-063.40e-021.86716801746
GO:0006281DNA repair3.76e-066.14e-023.400722264
GO:0035267NuA4 histone acetyltransferase complex5.25e-068.58e-026.4143414
GO:0006260DNA replication1.46e-052.38e-013.993512125
GO:0032201telomere maintenance via semi-conservative replication2.19e-053.58e-015.7623722
GO:0000722telomere maintenance via recombination3.68e-056.00e-015.5213726
GO:0044822poly(A) RNA binding4.98e-058.12e-012.02211501078
GO:0006271DNA strand elongation involved in DNA replication6.30e-051.00e+005.2683931
GO:0016363nuclear matrix8.16e-051.00e+004.11341192
GO:0043066negative regulation of apoptotic process9.08e-051.00e+002.686730433
GO:0019901protein kinase binding1.37e-041.00e+002.900621320
GO:0005730nucleolus1.58e-041.00e+001.62013701684
GO:0000812Swr1 complex1.71e-041.00e+006.637238
GO:0019773proteasome core complex, alpha-subunit complex1.71e-041.00e+006.637258
GO:0000075cell cycle checkpoint2.19e-041.00e+006.467229
GO:0003684damaged DNA binding2.82e-041.00e+004.54931151
GO:0003725double-stranded RNA binding3.34e-041.00e+004.4673654
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding3.34e-041.00e+004.4673554
GO:00709353'-UTR-mediated mRNA stabilization4.00e-041.00e+006.0522212
GO:0043968histone H2A acetylation4.00e-041.00e+006.0522312
GO:0000723telomere maintenance4.34e-041.00e+004.3393859
GO:0000738DNA catabolic process, exonucleolytic4.72e-041.00e+005.9362213
GO:0006915apoptotic process4.94e-041.00e+002.287734571
GO:0031011Ino80 complex5.50e-041.00e+005.8302314
GO:0000166nucleotide binding5.68e-041.00e+002.87156272
GO:0006310DNA recombination6.30e-041.00e+004.1563467
GO:00084083'-5' exonuclease activity7.23e-041.00e+005.6372216
GO:0000398mRNA splicing, via spliceosome7.62e-041.00e+003.271412165
GO:0000785chromatin8.10e-041.00e+004.0323573
GO:0006259DNA metabolic process1.02e-031.00e+005.3892319
GO:0071013catalytic step 2 spliceosome1.02e-031.00e+003.9183779
GO:0003678DNA helicase activity1.02e-031.00e+005.3892319
GO:0006298mismatch repair1.14e-031.00e+005.3152620
GO:0006297nucleotide-excision repair, DNA gap filling1.38e-031.00e+005.1772522
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle1.38e-031.00e+005.1772322
GO:0006270DNA replication initiation1.38e-031.00e+005.1772522
GO:0043044ATP-dependent chromatin remodeling1.51e-031.00e+005.1132423
GO:0042470melanosome1.58e-031.00e+003.69831092
GO:0006206pyrimidine nucleobase metabolic process1.64e-031.00e+005.0522224
GO:0003723RNA binding1.86e-031.00e+002.487519355
GO:0071339MLL1 complex2.08e-031.00e+004.8822327
GO:0043967histone H4 acetylation2.23e-031.00e+004.8302328
GO:0031492nucleosomal DNA binding2.23e-031.00e+004.8302428
GO:0003730mRNA 3'-UTR binding2.39e-031.00e+004.7792229
GO:0003887DNA-directed DNA polymerase activity2.39e-031.00e+004.7792329
GO:0018467formaldehyde dehydrogenase activity2.51e-031.00e+008.637111
GO:0008309double-stranded DNA exodeoxyribonuclease activity2.51e-031.00e+008.637111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.51e-031.00e+008.637111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity2.51e-031.00e+008.637111
GO:0070335aspartate binding2.51e-031.00e+008.637111
GO:0051903S-(hydroxymethyl)glutathione dehydrogenase activity2.51e-031.00e+008.637111
GO:0032558adenyl deoxyribonucleotide binding2.51e-031.00e+008.637111
GO:0090230regulation of centromere complex assembly2.51e-031.00e+008.637111
GO:0004151dihydroorotase activity2.51e-031.00e+008.637111
GO:0004632phosphopantothenate--cysteine ligase activity2.51e-031.00e+008.637111
GO:0019521D-gluconate metabolic process2.51e-031.00e+008.637111
GO:0004070aspartate carbamoyltransferase activity2.51e-031.00e+008.637111
GO:0007067mitotic nuclear division2.63e-031.00e+002.785413231
GO:0051219phosphoprotein binding2.91e-031.00e+004.6372332
GO:0033572transferrin transport2.91e-031.00e+004.6372632
GO:0030529ribonucleoprotein complex2.92e-031.00e+003.38938114
GO:0005635nuclear envelope3.06e-031.00e+003.36436116
GO:0006325chromatin organization3.61e-031.00e+003.27934123
GO:0050681androgen receptor binding4.09e-031.00e+004.3892438
GO:0006284base-excision repair4.30e-031.00e+004.3512739
GO:0030521androgen receptor signaling pathway4.75e-031.00e+004.2792241
GO:0032508DNA duplex unwinding4.97e-031.00e+004.2452442
GO:0004832valine-tRNA ligase activity5.02e-031.00e+007.637112
GO:0006272leading strand elongation5.02e-031.00e+007.637122
GO:0045252oxoglutarate dehydrogenase complex5.02e-031.00e+007.637122
GO:0002176male germ cell proliferation5.02e-031.00e+007.637112
GO:0097286iron ion import5.02e-031.00e+007.637112
GO:0006407rRNA export from nucleus5.02e-031.00e+007.637112
GO:0006438valyl-tRNA aminoacylation5.02e-031.00e+007.637112
GO:0046294formaldehyde catabolic process5.02e-031.00e+007.637112
GO:0071920cleavage body5.02e-031.00e+007.637112
GO:0061034olfactory bulb mitral cell layer development5.02e-031.00e+007.637112
GO:00082963'-5'-exodeoxyribonuclease activity5.02e-031.00e+007.637112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.02e-031.00e+007.637112
GO:0004998transferrin receptor activity5.02e-031.00e+007.637112
GO:0019322pentose biosynthetic process5.02e-031.00e+007.637112
GO:0031134sister chromatid biorientation5.02e-031.00e+007.637112
GO:0005055laminin receptor activity5.02e-031.00e+007.637112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis5.02e-031.00e+007.637122
GO:0070409carbamoyl phosphate biosynthetic process5.02e-031.00e+007.637112
GO:0006457protein folding6.17e-031.00e+003.00338149
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity6.20e-031.00e+004.0822347
GO:0043234protein complex6.64e-031.00e+002.408417300
GO:0031100organ regeneration6.99e-031.00e+003.9932450
GO:0040008regulation of growth7.26e-031.00e+003.9642351
GO:0042802identical protein binding7.41e-031.00e+002.019518491
GO:0009263deoxyribonucleotide biosynthetic process7.52e-031.00e+007.052113
GO:0018119peptidyl-cysteine S-nitrosylation7.52e-031.00e+007.052113
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity7.52e-031.00e+007.052113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb7.52e-031.00e+007.052113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity7.52e-031.00e+007.052113
GO:0071459protein localization to chromosome, centromeric region7.52e-031.00e+007.052113
GO:0071899negative regulation of estrogen receptor binding7.52e-031.00e+007.052113
GO:0005850eukaryotic translation initiation factor 2 complex7.52e-031.00e+007.052113
GO:1900126negative regulation of hyaluronan biosynthetic process7.52e-031.00e+007.052113
GO:0071733transcriptional activation by promoter-enhancer looping7.52e-031.00e+007.052113
GO:0000056ribosomal small subunit export from nucleus7.52e-031.00e+007.052113
GO:0009051pentose-phosphate shunt, oxidative branch7.52e-031.00e+007.052113
GO:0004748ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor7.52e-031.00e+007.052113
GO:0044205'de novo' UMP biosynthetic process7.52e-031.00e+007.052113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle7.52e-031.00e+007.052113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process7.52e-031.00e+007.052113
GO:0071439clathrin complex7.52e-031.00e+007.052113
GO:0090305nucleic acid phosphodiester bond hydrolysis8.11e-031.00e+003.8822254
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.00e-021.00e+006.637114
GO:0000212meiotic spindle organization1.00e-021.00e+006.637114
GO:003068690S preribosome1.00e-021.00e+006.637114
GO:0005658alpha DNA polymerase:primase complex1.00e-021.00e+006.637114
GO:0071922regulation of cohesin localization to chromatin1.00e-021.00e+006.637114
GO:0032051clathrin light chain binding1.00e-021.00e+006.637114
GO:0043137DNA replication, removal of RNA primer1.00e-021.00e+006.637114
GO:0019788NEDD8 ligase activity1.00e-021.00e+006.637114
GO:0051409response to nitrosative stress1.00e-021.00e+006.637114
GO:0006068ethanol catabolic process1.00e-021.00e+006.637114
GO:0043141ATP-dependent 5'-3' DNA helicase activity1.00e-021.00e+006.637114
GO:0006104succinyl-CoA metabolic process1.00e-021.00e+006.637114
GO:0006543glutamine catabolic process1.00e-021.00e+006.637114
GO:0031467Cul7-RING ubiquitin ligase complex1.00e-021.00e+006.637114
GO:0043550regulation of lipid kinase activity1.00e-021.00e+006.637114
GO:0000055ribosomal large subunit export from nucleus1.00e-021.00e+006.637114
GO:0035189Rb-E2F complex1.00e-021.00e+006.637114
GO:0034349glial cell apoptotic process1.00e-021.00e+006.637114
GO:0034088maintenance of mitotic sister chromatid cohesion1.00e-021.00e+006.637114
GO:0008853exodeoxyribonuclease III activity1.00e-021.00e+006.637114
GO:0006273lagging strand elongation1.00e-021.00e+006.637114
GO:0003896DNA primase activity1.00e-021.00e+006.637124
GO:1903077negative regulation of protein localization to plasma membrane1.00e-021.00e+006.637114
GO:0031625ubiquitin protein ligase binding1.03e-021.00e+002.730313180
GO:0006302double-strand break repair1.06e-021.00e+003.6832862
GO:0042995cell projection1.09e-021.00e+003.6602663
GO:0051414response to cortisol1.25e-021.00e+006.315115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.25e-021.00e+006.315125
GO:0001940male pronucleus1.25e-021.00e+006.315115
GO:0001882nucleoside binding1.25e-021.00e+006.315115
GO:0032407MutSalpha complex binding1.25e-021.00e+006.315115
GO:2000001regulation of DNA damage checkpoint1.25e-021.00e+006.315115
GO:0008622epsilon DNA polymerase complex1.25e-021.00e+006.315115
GO:0006269DNA replication, synthesis of RNA primer1.25e-021.00e+006.315125
GO:0031461cullin-RING ubiquitin ligase complex1.25e-021.00e+006.315115
GO:0071169establishment of protein localization to chromatin1.25e-021.00e+006.315115
GO:0043248proteasome assembly1.25e-021.00e+006.315115
GO:0048667cell morphogenesis involved in neuron differentiation1.25e-021.00e+006.315115
GO:0004022alcohol dehydrogenase (NAD) activity1.25e-021.00e+006.315115
GO:0030891VCB complex1.25e-021.00e+006.315125
GO:00171085'-flap endonuclease activity1.25e-021.00e+006.315115
GO:0005827polar microtubule1.25e-021.00e+006.315115
GO:0000730DNA recombinase assembly1.25e-021.00e+006.315135
GO:0006734NADH metabolic process1.25e-021.00e+006.315115
GO:0004523RNA-DNA hybrid ribonuclease activity1.25e-021.00e+006.315115
GO:0030976thiamine pyrophosphate binding1.25e-021.00e+006.315115
GO:0006338chromatin remodeling1.26e-021.00e+003.5492468
GO:0003697single-stranded DNA binding1.30e-021.00e+003.5282969
GO:0003924GTPase activity1.43e-021.00e+002.55739203
GO:0055086nucleobase-containing small molecule metabolic process1.45e-021.00e+003.4472573
GO:0043353enucleate erythrocyte differentiation1.50e-021.00e+006.052116
GO:0009108coenzyme biosynthetic process1.50e-021.00e+006.052116
GO:0030130clathrin coat of trans-Golgi network vesicle1.50e-021.00e+006.052116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.50e-021.00e+006.052116
GO:0035925mRNA 3'-UTR AU-rich region binding1.50e-021.00e+006.052116
GO:0021860pyramidal neuron development1.50e-021.00e+006.052116
GO:0030118clathrin coat1.50e-021.00e+006.052116
GO:0031466Cul5-RING ubiquitin ligase complex1.50e-021.00e+006.052116
GO:0021695cerebellar cortex development1.50e-021.00e+006.052116
GO:0030957Tat protein binding1.50e-021.00e+006.052146
GO:0046134pyrimidine nucleoside biosynthetic process1.50e-021.00e+006.052116
GO:0032405MutLalpha complex binding1.50e-021.00e+006.052126
GO:0007265Ras protein signal transduction1.52e-021.00e+003.4082375
GO:0008584male gonad development1.60e-021.00e+003.3702277
GO:0000028ribosomal small subunit assembly1.75e-021.00e+005.830117
GO:0002161aminoacyl-tRNA editing activity1.75e-021.00e+005.830127
GO:0001939female pronucleus1.75e-021.00e+005.830117
GO:0031462Cul2-RING ubiquitin ligase complex1.75e-021.00e+005.830127
GO:0030132clathrin coat of coated pit1.75e-021.00e+005.830117
GO:0000930gamma-tubulin complex1.75e-021.00e+005.830117
GO:0016018cyclosporin A binding1.75e-021.00e+005.830117
GO:0006184GTP catabolic process1.77e-021.00e+002.44039220
GO:0005524ATP binding1.78e-021.00e+001.2348461354
GO:0005681spliceosomal complex1.84e-021.00e+003.2622383
GO:0006898receptor-mediated endocytosis1.97e-021.00e+003.2112286
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.99e-021.00e+005.637128
GO:0070688MLL5-L complex1.99e-021.00e+005.637118
GO:0006554lysine catabolic process1.99e-021.00e+005.637128
GO:0045116protein neddylation1.99e-021.00e+005.637128
GO:0008380RNA splicing2.03e-021.00e+002.364313232
GO:0003690double-stranded DNA binding2.19e-021.00e+003.1292491
GO:00084095'-3' exonuclease activity2.24e-021.00e+005.467119
GO:0014075response to amine2.24e-021.00e+005.467119
GO:0003016respiratory system process2.24e-021.00e+005.467119
GO:0005847mRNA cleavage and polyadenylation specificity factor complex2.24e-021.00e+005.467119
GO:0015937coenzyme A biosynthetic process2.24e-021.00e+005.467119
GO:0016538cyclin-dependent protein serine/threonine kinase regulator activity2.24e-021.00e+005.467119
GO:0016605PML body2.24e-021.00e+003.1132592
GO:0097284hepatocyte apoptotic process2.24e-021.00e+005.467129
GO:0006228UTP biosynthetic process2.24e-021.00e+005.467119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.24e-021.00e+005.467119
GO:0031000response to caffeine2.24e-021.00e+005.467129
GO:0005200structural constituent of cytoskeleton2.28e-021.00e+003.0982793
GO:0001649osteoblast differentiation2.37e-021.00e+003.0672695
GO:0006379mRNA cleavage2.48e-021.00e+005.3151110
GO:0006450regulation of translational fidelity2.48e-021.00e+005.3151210
GO:0008195phosphatidate phosphatase activity2.48e-021.00e+005.3151110
GO:0000731DNA synthesis involved in DNA repair2.48e-021.00e+005.3151110
GO:0015939pantothenate metabolic process2.48e-021.00e+005.3151110
GO:0006069ethanol oxidation2.48e-021.00e+005.3151110
GO:0051775response to redox state2.48e-021.00e+005.3151110
GO:0021756striatum development2.48e-021.00e+005.3151110
GO:0006098pentose-phosphate shunt2.73e-021.00e+005.1771311
GO:0021846cell proliferation in forebrain2.73e-021.00e+005.1771111
GO:0010569regulation of double-strand break repair via homologous recombination2.73e-021.00e+005.1771111
GO:0031571mitotic G1 DNA damage checkpoint2.73e-021.00e+005.1771311
GO:0042551neuron maturation2.73e-021.00e+005.1771211
GO:0045651positive regulation of macrophage differentiation2.73e-021.00e+005.1771211
GO:0045120pronucleus2.73e-021.00e+005.1771111
GO:0033762response to glucagon2.73e-021.00e+005.1771111
GO:2000036regulation of stem cell maintenance2.73e-021.00e+005.1771211
GO:0035458cellular response to interferon-beta2.73e-021.00e+005.1771211
GO:0051290protein heterotetramerization2.73e-021.00e+005.1771211
GO:0019985translesion synthesis2.97e-021.00e+005.0521212
GO:0009650UV protection2.97e-021.00e+005.0521112
GO:0048255mRNA stabilization2.97e-021.00e+005.0521112
GO:0051146striated muscle cell differentiation2.97e-021.00e+005.0521112
GO:0021794thalamus development2.97e-021.00e+005.0521112
GO:0005838proteasome regulatory particle2.97e-021.00e+005.0521712
GO:0032479regulation of type I interferon production3.22e-021.00e+004.9361213
GO:0006646phosphatidylethanolamine biosynthetic process3.22e-021.00e+004.9361213
GO:0005662DNA replication factor A complex3.22e-021.00e+004.9361313
GO:0045780positive regulation of bone resorption3.22e-021.00e+004.9361113
GO:0008266poly(U) RNA binding3.22e-021.00e+004.9361113
GO:0005819spindle3.32e-021.00e+002.80427114
GO:0019058viral life cycle3.38e-021.00e+002.791210115
GO:0072562blood microparticle3.43e-021.00e+002.77924116
GO:0005504fatty acid binding3.46e-021.00e+004.8301114
GO:0004527exonuclease activity3.46e-021.00e+004.8301114
GO:0007020microtubule nucleation3.46e-021.00e+004.8301114
GO:0007095mitotic G2 DNA damage checkpoint3.46e-021.00e+004.8301114
GO:0045445myoblast differentiation3.70e-021.00e+004.7301215
GO:0035066positive regulation of histone acetylation3.70e-021.00e+004.7301115
GO:0017091AU-rich element binding3.70e-021.00e+004.7301115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.70e-021.00e+004.7301115
GO:0016514SWI/SNF complex3.70e-021.00e+004.7301315
GO:0050998nitric-oxide synthase binding3.95e-021.00e+004.6371116
GO:00061032-oxoglutarate metabolic process3.95e-021.00e+004.6371116
GO:0010243response to organonitrogen compound4.19e-021.00e+004.5491217
GO:0045070positive regulation of viral genome replication4.19e-021.00e+004.5491117
GO:0045777positive regulation of blood pressure4.19e-021.00e+004.5491117
GO:0075733intracellular transport of virus4.19e-021.00e+004.5491217
GO:0022624proteasome accessory complex4.19e-021.00e+004.5491917
GO:0006413translational initiation4.28e-021.00e+002.603212131
GO:0000790nuclear chromatin4.40e-021.00e+002.58227133
GO:0071392cellular response to estradiol stimulus4.43e-021.00e+004.4671118
GO:0006541glutamine metabolic process4.43e-021.00e+004.4671118
GO:0031122cytoplasmic microtubule organization4.43e-021.00e+004.4671218
GO:0035861site of double-strand break4.43e-021.00e+004.4671118
GO:0004004ATP-dependent RNA helicase activity4.43e-021.00e+004.4671218
GO:0006303double-strand break repair via nonhomologous end joining4.43e-021.00e+004.4671318
GO:0015949nucleobase-containing small molecule interconversion4.43e-021.00e+004.4671218
GO:0031982vesicle4.45e-021.00e+002.571210134
GO:0000086G2/M transition of mitotic cell cycle4.64e-021.00e+002.53927137
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.67e-021.00e+004.3891119
GO:0048863stem cell differentiation4.67e-021.00e+004.3891119
GO:0005525GTP binding4.89e-021.00e+001.864311328
GO:2000134negative regulation of G1/S transition of mitotic cell cycle4.91e-021.00e+004.3151220
GO:0005719nuclear euchromatin4.91e-021.00e+004.3151220
GO:0016887ATPase activity5.07e-021.00e+002.46727144
GO:0000718nucleotide-excision repair, DNA damage removal5.15e-021.00e+004.2451521
GO:0071364cellular response to epidermal growth factor stimulus5.15e-021.00e+004.2451121
GO:0061024membrane organization5.19e-021.00e+002.44725146
GO:0030316osteoclast differentiation5.39e-021.00e+004.1771222
GO:0006378mRNA polyadenylation5.39e-021.00e+004.1771122
GO:0006656phosphatidylcholine biosynthetic process5.39e-021.00e+004.1771322
GO:0033574response to testosterone5.39e-021.00e+004.1771222
GO:0030863cortical cytoskeleton5.39e-021.00e+004.1771122
GO:0036464cytoplasmic ribonucleoprotein granule5.39e-021.00e+004.1771422
GO:0007052mitotic spindle organization5.39e-021.00e+004.1771222
GO:0031463Cul3-RING ubiquitin ligase complex5.62e-021.00e+004.1131223
GO:0043236laminin binding5.62e-021.00e+004.1131123
GO:0006513protein monoubiquitination5.62e-021.00e+004.1131123
GO:0045879negative regulation of smoothened signaling pathway5.62e-021.00e+004.1131123
GO:0008135translation factor activity, nucleic acid binding5.86e-021.00e+004.0521424
GO:0000794condensed nuclear chromosome5.86e-021.00e+004.0521224
GO:0046777protein autophosphorylation5.97e-021.00e+002.33323158
GO:0006611protein export from nucleus6.10e-021.00e+003.9931425
GO:0017144drug metabolic process6.10e-021.00e+003.9931125
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.34e-021.00e+003.9361226
GO:0030148sphingolipid biosynthetic process6.34e-021.00e+003.9361126
GO:0004519endonuclease activity6.34e-021.00e+003.9361126
GO:0004003ATP-dependent DNA helicase activity6.57e-021.00e+003.8821327
GO:0034080CENP-A containing nucleosome assembly6.57e-021.00e+003.8821227
GO:0048565digestive tract development6.57e-021.00e+003.8821127
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.65e-021.00e+002.24525168
GO:0043022ribosome binding6.81e-021.00e+003.8301328
GO:0019894kinesin binding6.81e-021.00e+003.8301128
GO:0006099tricarboxylic acid cycle7.04e-021.00e+003.7791329
GO:0019005SCF ubiquitin ligase complex7.04e-021.00e+003.7791129
GO:0030669clathrin-coated endocytic vesicle membrane7.04e-021.00e+003.7791129
GO:0071897DNA biosynthetic process7.04e-021.00e+003.7791229
GO:0000287magnesium ion binding7.07e-021.00e+002.19425174
GO:0042254ribosome biogenesis7.27e-021.00e+003.7301130
GO:0007346regulation of mitotic cell cycle7.27e-021.00e+003.7301330
GO:0031623receptor internalization7.51e-021.00e+003.6831131
GO:0007093mitotic cell cycle checkpoint7.51e-021.00e+003.6831231
GO:0050661NADP binding7.74e-021.00e+003.6371132
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolytic7.74e-021.00e+003.6371132
GO:0034644cellular response to UV7.74e-021.00e+003.6371532
GO:0031072heat shock protein binding7.97e-021.00e+003.5921233
GO:0000413protein peptidyl-prolyl isomerization8.20e-021.00e+003.5491134
GO:0003755peptidyl-prolyl cis-trans isomerase activity8.20e-021.00e+003.5491134
GO:0042277peptide binding8.44e-021.00e+003.5081235
GO:0032588trans-Golgi network membrane8.67e-021.00e+003.4671136
GO:0034332adherens junction organization8.67e-021.00e+003.4671136
GO:0051402neuron apoptotic process8.67e-021.00e+003.4671236
GO:0001895retina homeostasis8.67e-021.00e+003.4671136
GO:0001102RNA polymerase II activating transcription factor binding8.90e-021.00e+003.4271437
GO:0051084'de novo' posttranslational protein folding8.90e-021.00e+003.4271437
GO:0018107peptidyl-threonine phosphorylation8.90e-021.00e+003.4271137
GO:00515394 iron, 4 sulfur cluster binding8.90e-021.00e+003.4271337
GO:0070527platelet aggregation9.13e-021.00e+003.3891238
GO:0021766hippocampus development9.35e-021.00e+003.3511439
GO:0000737DNA catabolic process, endonucleolytic9.35e-021.00e+003.3511239
GO:0031490chromatin DNA binding9.35e-021.00e+003.3511239
GO:0006096glycolytic process9.35e-021.00e+003.3511439
GO:0022627cytosolic small ribosomal subunit9.35e-021.00e+003.3511339
GO:0032092positive regulation of protein binding9.35e-021.00e+003.3511339
GO:0007595lactation9.35e-021.00e+003.3511239
GO:0000781chromosome, telomeric region9.58e-021.00e+003.3151240
GO:0030145manganese ion binding9.81e-021.00e+003.2791141
GO:0043195terminal bouton9.81e-021.00e+003.2791141
GO:0006418tRNA aminoacylation for protein translation1.00e-011.00e+003.2451542
GO:0031124mRNA 3'-end processing1.00e-011.00e+003.2451242
GO:0035914skeletal muscle cell differentiation1.00e-011.00e+003.2451142
GO:0005737cytoplasm1.03e-011.00e+000.48714983976
GO:0014070response to organic cyclic compound1.03e-011.00e+003.2111343
GO:0010212response to ionizing radiation1.03e-011.00e+003.2111143
GO:0048146positive regulation of fibroblast proliferation1.05e-011.00e+003.1771244
GO:0007286spermatid development1.05e-011.00e+003.1771144
GO:0006892post-Golgi vesicle-mediated transport1.05e-011.00e+003.1771244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.05e-011.00e+003.1771244
GO:0015030Cajal body1.07e-011.00e+003.1451245
GO:0043966histone H3 acetylation1.07e-011.00e+003.1451245
GO:0006369termination of RNA polymerase II transcription1.07e-011.00e+003.1451245
GO:0006631fatty acid metabolic process1.07e-011.00e+003.1451145
GO:0021762substantia nigra development1.09e-011.00e+003.1131146
GO:0030136clathrin-coated vesicle1.09e-011.00e+003.1131146
GO:0001047core promoter binding1.09e-011.00e+003.1131246
GO:0006283transcription-coupled nucleotide-excision repair1.09e-011.00e+003.1131846
GO:0045727positive regulation of translation1.09e-011.00e+003.1131446
GO:0019003GDP binding1.14e-011.00e+003.0521248
GO:0003743translation initiation factor activity1.16e-011.00e+003.0221449
GO:0001523retinoid metabolic process1.18e-011.00e+002.9931250
GO:0001948glycoprotein binding1.18e-011.00e+002.9931350
GO:0006412translation1.18e-011.00e+001.760215235
GO:0035690cellular response to drug1.18e-011.00e+002.9931250
GO:0005739mitochondrion1.20e-011.00e+000.9285241046
GO:0006091generation of precursor metabolites and energy1.21e-011.00e+002.9641351
GO:0005905coated pit1.21e-011.00e+002.9641251
GO:0003713transcription coactivator activity1.21e-011.00e+001.736210239
GO:0045893positive regulation of transcription, DNA-templated1.23e-011.00e+001.294317487
GO:0060041retina development in camera-type eye1.25e-011.00e+002.9091353
GO:0019900kinase binding1.27e-011.00e+002.8821154
GO:0044267cellular protein metabolic process1.27e-011.00e+001.271324495
GO:0050680negative regulation of epithelial cell proliferation1.27e-011.00e+002.8821154
GO:0000226microtubule cytoskeleton organization1.29e-011.00e+002.8561355
GO:0000932cytoplasmic mRNA processing body1.32e-011.00e+002.8301356
GO:0007613memory1.32e-011.00e+002.8301256
GO:0043025neuronal cell body1.33e-011.00e+001.64824254
GO:0006879cellular iron ion homeostasis1.34e-011.00e+002.8041557
GO:0000724double-strand break repair via homologous recombination1.34e-011.00e+002.8041657
GO:0051087chaperone binding1.38e-011.00e+002.7541659
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.38e-011.00e+002.7541459
GO:0045216cell-cell junction organization1.38e-011.00e+002.7541259
GO:0005643nuclear pore1.38e-011.00e+002.7541459
GO:0031966mitochondrial membrane1.38e-011.00e+002.7541159
GO:0032481positive regulation of type I interferon production1.42e-011.00e+002.7061661
GO:0019903protein phosphatase binding1.47e-011.00e+002.6601463
GO:0006469negative regulation of protein kinase activity1.51e-011.00e+002.6151265
GO:0001558regulation of cell growth1.53e-011.00e+002.5921466
GO:0006665sphingolipid metabolic process1.58e-011.00e+002.5491268
GO:0009055electron carrier activity1.58e-011.00e+002.5491168
GO:0006289nucleotide-excision repair1.60e-011.00e+002.52811269
GO:0019899enzyme binding1.63e-011.00e+001.467211288
GO:0034329cell junction assembly1.64e-011.00e+002.4871171
GO:0055037recycling endosome1.68e-011.00e+002.4471273
GO:0032355response to estradiol1.68e-011.00e+002.4471573
GO:0003729mRNA binding1.68e-011.00e+002.4471473
GO:0006767water-soluble vitamin metabolic process1.72e-011.00e+002.4081375
GO:0031175neuron projection development1.72e-011.00e+002.4081175
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.74e-011.00e+002.3891376
GO:0046474glycerophospholipid biosynthetic process1.74e-011.00e+002.3891376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.76e-011.00e+002.3701577
GO:0006200ATP catabolic process1.76e-011.00e+001.394214303
GO:0006766vitamin metabolic process1.79e-011.00e+002.3511378
GO:0006334nucleosome assembly1.81e-011.00e+002.3331479
GO:0007565female pregnancy1.83e-011.00e+002.3151280
GO:0019083viral transcription1.85e-011.00e+002.2971881
GO:0051301cell division1.85e-011.00e+002.2971681
GO:0001889liver development1.87e-011.00e+002.2791382
GO:0047485protein N-terminus binding1.95e-011.00e+002.2111486
GO:0006415translational termination1.97e-011.00e+002.1941887
GO:0043231intracellular membrane-bounded organelle2.03e-011.00e+001.26228332
GO:0003682chromatin binding2.05e-011.00e+001.253212334
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II2.07e-011.00e+002.1131492
GO:0006928cellular component movement2.07e-011.00e+002.1131792
GO:0006414translational elongation2.09e-011.00e+002.09811193
GO:0016311dephosphorylation2.11e-011.00e+002.0821394
GO:0051082unfolded protein binding2.13e-011.00e+002.0671695
GO:0071456cellular response to hypoxia2.19e-011.00e+002.0221498
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.31e-011.00e+001.93618104
GO:0014069postsynaptic density2.35e-011.00e+001.90911106
GO:0016023cytoplasmic membrane-bounded vesicle2.37e-011.00e+001.89513107
GO:0005925focal adhesion2.38e-011.00e+001.106218370
GO:0005815microtubule organizing center2.42e-011.00e+001.85614110
GO:0042127regulation of cell proliferation2.44e-011.00e+001.84214111
GO:0015630microtubule cytoskeleton2.46e-011.00e+001.83015112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.50e-011.00e+001.804110114
GO:0044237cellular metabolic process2.58e-011.00e+001.75413118
GO:0046982protein heterodimerization activity2.65e-011.00e+000.997211399
GO:0032496response to lipopolysaccharide2.65e-011.00e+001.70614122
GO:0007568aging2.67e-011.00e+001.69413123
GO:0007219Notch signaling pathway2.71e-011.00e+001.67114125
GO:0007050cell cycle arrest2.73e-011.00e+001.66017126
GO:0006511ubiquitin-dependent protein catabolic process2.74e-011.00e+001.64815127
GO:0009615response to virus2.83e-011.00e+001.59216132
GO:0006644phospholipid metabolic process2.93e-011.00e+001.53915137
GO:0003735structural constituent of ribosome3.00e-011.00e+001.49718141
GO:0016055Wnt signaling pathway3.00e-011.00e+001.49716141
GO:0007507heart development3.00e-011.00e+001.49715141
GO:0005198structural molecule activity3.31e-011.00e+001.32414159
GO:0055114oxidation-reduction process3.42e-011.00e+000.727211481
GO:0006397mRNA processing3.48e-011.00e+001.23613169
GO:0030424axon3.53e-011.00e+001.21113172
GO:0006886intracellular protein transport3.54e-011.00e+001.20214173
GO:0005768endosome3.56e-011.00e+001.19415174
GO:0016607nuclear speck3.58e-011.00e+001.18614175
GO:0004672protein kinase activity3.62e-011.00e+001.16112178
GO:0019904protein domain specific binding3.67e-011.00e+001.13716181
GO:0009897external side of plasma membrane3.71e-011.00e+001.12114183
GO:0015629actin cytoskeleton3.71e-011.00e+001.12115183
GO:0032403protein complex binding3.74e-011.00e+001.10617185
GO:0001701in utero embryonic development4.12e-011.00e+000.92316210
GO:0005622intracellular4.36e-011.00e+000.81715226
GO:0005759mitochondrial matrix4.46e-011.00e+000.773112233
GO:0042803protein homodimerization activity4.62e-011.00e+000.368211617
GO:0045087innate immune response4.62e-011.00e+000.370220616
GO:0008134transcription factor binding4.64e-011.00e+000.69418246
GO:0004842ubiquitin-protein transferase activity4.77e-011.00e+000.63714256
GO:0005789endoplasmic reticulum membrane4.78e-011.00e+000.324210636
GO:0005794Golgi apparatus4.90e-011.00e+000.293214650
GO:0005975carbohydrate metabolic process5.01e-011.00e+000.53915274
GO:0006357regulation of transcription from RNA polymerase II promoter5.02e-011.00e+000.53416275
GO:0007283spermatogenesis5.03e-011.00e+000.52816276
GO:0008270zinc ion binding5.07e-011.00e+000.1633121067
GO:0046872metal ion binding5.09e-011.00e+000.1204241465
GO:0007264small GTPase mediated signal transduction5.21e-011.00e+000.45713290
GO:0016567protein ubiquitination5.32e-011.00e+000.41315299
GO:0005856cytoskeleton5.46e-011.00e+000.35618311
GO:0004674protein serine/threonine kinase activity5.47e-011.00e+000.35116312
GO:0007411axon guidance5.64e-011.00e+000.28419327
GO:0008283cell proliferation5.69e-011.00e+000.266112331
GO:0005813centrosome5.78e-011.00e+000.232112339
GO:0007275multicellular organismal development5.83e-011.00e+000.21115344
GO:0043565sequence-specific DNA binding6.05e-011.00e+000.12514365
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.11e-011.00e+00-0.027219811
GO:0007155cell adhesion6.24e-011.00e+000.05218384
GO:0009986cell surface6.59e-011.00e+00-0.08419422
GO:0045892negative regulation of transcription, DNA-templated6.61e-011.00e+00-0.091114424
GO:0006366transcription from RNA polymerase II promoter6.61e-011.00e+00-0.094112425
GO:0003677DNA binding6.71e-011.00e+00-0.1783261351
GO:0007596blood coagulation6.94e-011.00e+00-0.221114464
GO:0006468protein phosphorylation6.96e-011.00e+00-0.230110467
GO:0007165signal transduction6.98e-011.00e+00-0.255217950
GO:0005615extracellular space7.30e-011.00e+00-0.3432171010
GO:0055085transmembrane transport7.31e-011.00e+00-0.36918514
GO:0048471perinuclear region of cytoplasm7.37e-011.00e+00-0.394112523
GO:0006351transcription, DNA-templated7.74e-011.00e+00-0.4083251585
GO:0003700sequence-specific DNA binding transcription factor activity8.54e-011.00e+00-0.910111748
GO:0005887integral component of plasma membrane9.17e-011.00e+00-1.27217961
GO:0005576extracellular region9.35e-011.00e+00-1.398191049
GO:0006355regulation of transcription, DNA-templated9.44e-011.00e+00-1.4721171104
GO:0005886plasma membrane9.82e-011.00e+00-1.2473382834