meta-reg-snw-6169

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-56848 tai-screen-luciferase 6.375 2.94e-136 3.59e-07 2.58e-03 24 19
reg-snw-6169 tai-screen-luciferase 4.851 3.99e-26 2.70e-04 4.60e-04 8 5
int-snw-10296 tai-screen-luciferase 6.413 3.70e-138 2.79e-07 2.32e-03 18 15
int-snw-6150 tai-screen-luciferase 6.375 3.15e-136 3.60e-07 2.59e-03 23 17
int-snw-51382 tai-screen-luciferase 7.286 3.65e-186 4.21e-10 1.27e-04 13 12
int-snw-51741 tai-screen-luciferase 6.174 2.67e-126 1.32e-06 4.54e-03 24 19
tai-screen-luciferase-meta-reg-snw-6169 subnetwork

Genes (47)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 33-5.5457.555234--
MAPK8 5599 28-4.4036.468153--
CHMP2A 27243 33-9.0377.55541YesYes
RPS15 6209 30-5.0407.011116Yes-
COPA 1314 48-9.3955.672340YesYes
RNF20 56254 28-4.5646.17418--
RPS29 6235 17-8.3866.59729--
HSF1 3297 46-4.1795.027209-Yes
SRC 6714 28-2.8066.174419Yes-
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RPS16 6217 38-5.4444.880205--
EIF2S2 8894 31-4.3205.672103Yes-
CDC42 998 44-6.9604.707276YesYes
MAEA 10296 13-2.7936.41343--
ARL1 400 18-4.1428.046110-Yes
RPS11 6205 44-6.5887.555175Yes-
RPS6 6194 44-5.6038.046217Yes-
MRPS12 6183 35-5.4215.516341Yes-
TLK2 11011 21-4.0115.67214--
YBX1 4904 24-3.0335.516296--
RAN 5901 38-3.8094.325258YesYes
UBB 7314 30-4.2896.428147--
MAP3K14 9020 15-3.4626.375138-Yes
COPB1 1315 39-6.2219.063118YesYes
RPS23 6228 21-4.4856.375118Yes-
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
RPL38 6169 6-1.9924.8514Yes-
RPS24 6229 46-7.0348.389217Yes-
RPAP2 79871 153.1116.37549--
TCERG1 10915 28-3.8086.17458Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS4X 6191 44-6.7477.555263Yes-
COPZ1 22818 48-8.3019.06313YesYes
ATP6V1D 51382 30-4.1317.286149--
RPS15A 6210 36-5.4137.555177Yes-
WDR46 9277 31-4.2904.226101YesYes
WWOX 51741 28-2.4486.17438--
RPS27A 6233 45-5.6318.389344Yes-
RPS7 6201 15-4.3826.375165Yes-
SKP1 6500 26-3.7506.413203--
NFKBIB 4793 28-3.9786.17478--
SPHK2 56848 17-3.0106.37537--
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes
MRPL23 6150 15-2.5716.3759--

Interactions (137)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 SKP1 6500 pp -- int.I2D: BioGrid_Yeast, YeastLow
YBX1 4904 RPS23 6228 pp -- int.Intact: MI:0914(association)
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
RPS13 6207 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS7 6201 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
TCERG1 10915 WWOX 51741 pp -- int.I2D: BioGrid, MINT, Pawson1;
int.Mint: MI:0915(physical association)
EIF2S2 8894 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
SRC 6714 CKAP5 9793 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
YBX1 4904 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
YBX1 4904 RPS7 6201 pp -- int.Intact: MI:0914(association)
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RPS15 6209 RPS23 6228 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS7 6201 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS11 6205 pp -- int.Intact: MI:0914(association)
CDC42 998 UBB 7314 pp -- int.I2D: SOURAV_MAPK_HIGH
NFKBIB 4793 UBB 7314 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
SKP1 6500 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS6 6194 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS4X 6191 pp -- int.Intact: MI:0914(association)
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS23 6228 pp -- int.I2D: YeastLow, BioGrid_Yeast
RPS24 6229 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS15A 6210 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS13 6207 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
UBB 7314 WWOX 51741 pp -- int.I2D: BCI, HPRD;
int.HPRD: in vivo
UBB 7314 RNF20 56254 pp -- int.Intact: MI:0220(ubiquitination reaction);
int.I2D: IntAct
MRPS12 6183 RPS15 6209 pp -- int.I2D: YeastMedium
RPS8 6202 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 SKP1 6500 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 WWOX 51741 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
MAEA 10296 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
MRPL23 6150 MRPS12 6183 pd <> reg.ITFP.txt: no annot
ARL1 400 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS8 6202 pp -- int.Intact: MI:0914(association)
RPS7 6201 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 UBB 7314 pp -- int.I2D: BIND
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ARL1 400 COPA 1314 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RPS15 6209 pp -- int.I2D: YeastLow
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS6 6194 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
YBX1 4904 MRPL23 6150 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPL23 6150 pp -- int.Intact: MI:0914(association)
RPS7 6201 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS24 6229 pp -- int.Intact: MI:0914(association)
RPS16 6217 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
HSF1 3297 MAPK8 5599 pp -- int.I2D: HPRD, INNATEDB;
int.HPRD: in vitro, in vivo
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
NFKBIB 4793 SKP1 6500 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)
COPA 1314 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS11 6205 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 TLK2 11011 pd > reg.ITFP.txt: no annot
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 ARL1 400 pp -- int.I2D: BioGrid_Yeast
ARL1 400 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RAN 5901 SPHK2 56848 pp -- int.I2D: IntAct_Yeast, BIND_Yeast, MINT_Yeast, MIPS, YeastLow
CDC5L 988 YBX1 4904 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
YBX1 4904 RPAP2 79871 pp -- int.I2D: BioGrid
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS15A 6210 pp -- int.I2D: YeastMedium, INTEROLOG
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
CDC5L 988 RPL38 6169 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS29 6235 pp -- int.Intact: MI:0914(association)
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
MAPK8 5599 WWOX 51741 pp -- int.I2D: MINT, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
RAN 5901 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RAN 5901 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS7 6201 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast

Related GO terms (545)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit1.53e-292.50e-257.061152139
GO:0019058viral life cycle1.61e-292.63e-255.8421925115
GO:0019083viral transcription3.74e-266.10e-226.100162281
GO:0003735structural constituent of ribosome8.67e-261.41e-215.4701824141
GO:0006415translational termination1.30e-252.13e-215.997162287
GO:0006414translational elongation4.15e-256.77e-215.901162293
GO:0006413translational initiation1.82e-242.98e-205.4941727131
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.83e-244.62e-205.7391622104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.35e-232.21e-195.6071622114
GO:0006412translation2.38e-233.89e-194.8111929235
GO:0016032viral process1.22e-201.99e-163.8222237540
GO:0016071mRNA metabolic process2.08e-203.39e-164.7261729223
GO:0016070RNA metabolic process1.21e-191.97e-154.5791729247
GO:0005829cytosol4.31e-197.04e-152.24635742562
GO:0015935small ribosomal subunit6.02e-179.82e-137.3528917
GO:0010467gene expression4.68e-167.64e-123.3762036669
GO:0044267cellular protein metabolic process1.40e-142.29e-103.5761729495
GO:0044822poly(A) RNA binding2.67e-144.36e-102.82522421078
GO:0016020membrane6.06e-129.89e-082.25524481746
GO:0042274ribosomal small subunit biogenesis1.24e-102.03e-067.1775612
GO:0048205COPI coating of Golgi vesicle2.01e-103.28e-067.0615613
GO:0030126COPI vesicle coat2.01e-103.28e-067.0615613
GO:0061024membrane organization2.92e-104.77e-064.420911146
GO:0005925focal adhesion5.88e-099.59e-053.3681123370
GO:0006890retrograde vesicle-mediated transport, Golgi to ER8.09e-091.32e-046.1185625
GO:0005840ribosome1.65e-082.69e-045.14261059
GO:0030529ribonucleoprotein complex8.65e-071.41e-024.19268114
GO:0070062extracellular vesicular exosome1.74e-062.84e-021.53521512516
GO:0006364rRNA processing8.00e-061.31e-014.1775896
GO:0075733intracellular transport of virus1.48e-052.41e-015.9373317
GO:0006891intra-Golgi vesicle-mediated transport1.48e-052.41e-015.9373317
GO:0000056ribosomal small subunit export from nucleus2.43e-053.97e-017.855223
GO:0036464cytoplasmic ribonucleoprotein granule3.32e-055.41e-015.5653522
GO:0034146toll-like receptor 5 signaling pathway3.59e-055.86e-014.4174565
GO:0034166toll-like receptor 10 signaling pathway3.59e-055.86e-014.4174565
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway5.09e-058.31e-014.2904571
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway5.09e-058.31e-014.2904571
GO:0034162toll-like receptor 9 signaling pathway5.38e-058.78e-014.2704572
GO:0034134toll-like receptor 2 signaling pathway5.68e-059.27e-014.2504573
GO:0019843rRNA binding6.24e-051.00e+005.2703427
GO:0003723RNA binding6.46e-051.00e+002.776710355
GO:0035666TRIF-dependent toll-like receptor signaling pathway6.65e-051.00e+004.1924576
GO:0005515protein binding7.16e-051.00e+000.81331876127
GO:0002756MyD88-independent toll-like receptor signaling pathway7.37e-051.00e+004.1544578
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.07e-051.00e+007.118235
GO:0033119negative regulation of RNA splicing8.07e-051.00e+007.118225
GO:0002755MyD88-dependent toll-like receptor signaling pathway8.13e-051.00e+004.1184580
GO:0034138toll-like receptor 3 signaling pathway8.13e-051.00e+004.1184580
GO:0006886intracellular protein transport1.35e-041.00e+003.32756173
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway1.49e-041.00e+004.8553336
GO:0034142toll-like receptor 4 signaling pathway1.65e-041.00e+003.8554596
GO:0007249I-kappaB kinase/NF-kappaB signaling2.21e-041.00e+004.6673441
GO:0002224toll-like receptor signaling pathway2.69e-041.00e+003.67245109
GO:0007254JNK cascade4.23e-041.00e+004.3523351
GO:0051403stress-activated MAPK cascade5.01e-041.00e+004.2703454
GO:0019082viral protein processing5.26e-041.00e+005.8552212
GO:0016197endosomal transport6.18e-041.00e+004.1673358
GO:0032479regulation of type I interferon production6.20e-041.00e+005.7392213
GO:0000086G2/M transition of mitotic cell cycle6.41e-041.00e+003.34246137
GO:0005730nucleolus7.00e-041.00e+001.42313361684
GO:0032481positive regulation of type I interferon production7.17e-041.00e+004.0943361
GO:0000082G1/S transition of mitotic cell cycle8.99e-041.00e+003.211411150
GO:0031295T cell costimulation9.42e-041.00e+003.9593367
GO:0018105peptidyl-serine phosphorylation1.03e-031.00e+003.9163569
GO:0019068virion assembly1.07e-031.00e+005.3522217
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.07e-031.00e+003.8963870
GO:0043065positive regulation of apoptotic process1.11e-031.00e+002.66456274
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.26e-031.00e+003.8153874
GO:0043066negative regulation of apoptotic process1.44e-031.00e+002.267614433
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.52e-031.00e+003.7213879
GO:0007220Notch receptor processing1.81e-031.00e+004.9802222
GO:0005737cytoplasm1.81e-031.00e+000.87521653976
GO:0007173epidermal growth factor receptor signaling pathway2.19e-031.00e+002.86245191
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway2.33e-031.00e+004.7962225
GO:0005844polysome2.33e-031.00e+004.7962225
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.52e-031.00e+004.7392226
GO:0005978glycogen biosynthetic process2.52e-031.00e+004.7392226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity2.52e-031.00e+004.7392226
GO:0001649osteoblast differentiation2.57e-031.00e+003.4553395
GO:0071456cellular response to hypoxia2.81e-031.00e+003.4103398
GO:2001286regulation of caveolin-mediated endocytosis2.88e-031.00e+008.440111
GO:0071393cellular response to progesterone stimulus2.88e-031.00e+008.440111
GO:0033176proton-transporting V-type ATPase complex2.88e-031.00e+008.440111
GO:0033291eukaryotic 80S initiation complex2.88e-031.00e+008.440111
GO:003446390S preribosome assembly2.88e-031.00e+008.440111
GO:0006669sphinganine-1-phosphate biosynthetic process2.88e-031.00e+008.440111
GO:0022605oogenesis stage2.88e-031.00e+008.440111
GO:0021691cerebellar Purkinje cell layer maturation2.88e-031.00e+008.440111
GO:0032480negative regulation of type I interferon production3.81e-031.00e+004.4402232
GO:0097190apoptotic signaling pathway4.52e-031.00e+003.16733116
GO:0000209protein polyubiquitination4.52e-031.00e+003.16737116
GO:0034332adherens junction organization4.80e-031.00e+004.2702436
GO:0003713transcription coactivator activity4.88e-031.00e+002.53946239
GO:0051092positive regulation of NF-kappaB transcription factor activity5.56e-031.00e+003.05933125
GO:0007219Notch signaling pathway5.56e-031.00e+003.05934125
GO:0008481sphinganine kinase activity5.75e-031.00e+007.440112
GO:0071987WD40-repeat domain binding5.75e-031.00e+007.440112
GO:0060661submandibular salivary gland formation5.75e-031.00e+007.440112
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator5.75e-031.00e+007.440112
GO:0017050D-erythro-sphingosine kinase activity5.75e-031.00e+007.440112
GO:0071338positive regulation of hair follicle cell proliferation5.75e-031.00e+007.440112
GO:0002176male germ cell proliferation5.75e-031.00e+007.440112
GO:0048822enucleate erythrocyte development5.75e-031.00e+007.440112
GO:0072422signal transduction involved in DNA damage checkpoint5.75e-031.00e+007.440112
GO:0010632regulation of epithelial cell migration5.75e-031.00e+007.440112
GO:0001672regulation of chromatin assembly or disassembly5.75e-031.00e+007.440112
GO:0090135actin filament branching5.75e-031.00e+007.440112
GO:0007179transforming growth factor beta receptor signaling pathway6.20e-031.00e+003.00234130
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway6.80e-031.00e+004.0142243
GO:0048011neurotrophin TRK receptor signaling pathway7.77e-031.00e+002.34745273
GO:0045087innate immune response8.13e-031.00e+001.758611616
GO:0010641positive regulation of platelet-derived growth factor receptor signaling pathway8.61e-031.00e+006.855113
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding8.61e-031.00e+006.855113
GO:0003161cardiac conduction system development8.61e-031.00e+006.855113
GO:0048318axial mesoderm development8.61e-031.00e+006.855113
GO:0051154negative regulation of striated muscle cell differentiation8.61e-031.00e+006.855113
GO:0090045positive regulation of deacetylase activity8.61e-031.00e+006.855113
GO:0035033histone deacetylase regulator activity8.61e-031.00e+006.855113
GO:2000017positive regulation of determination of dorsal identity8.61e-031.00e+006.855113
GO:0051683establishment of Golgi localization8.61e-031.00e+006.855123
GO:0006670sphingosine metabolic process8.61e-031.00e+006.855113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity8.61e-031.00e+006.855113
GO:0033146regulation of intracellular estrogen receptor signaling pathway8.61e-031.00e+006.855113
GO:0005850eukaryotic translation initiation factor 2 complex8.61e-031.00e+006.855113
GO:0004705JUN kinase activity8.61e-031.00e+006.855113
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling8.85e-031.00e+002.81533148
GO:0007030Golgi organization9.11e-031.00e+003.7962350
GO:0030666endocytic vesicle membrane1.06e-021.00e+003.6852254
GO:0005198structural molecule activity1.08e-021.00e+002.71235159
GO:0008543fibroblast growth factor receptor signaling pathway1.08e-021.00e+002.71233159
GO:0043005neuron projection1.11e-021.00e+002.69436161
GO:003068690S preribosome1.15e-021.00e+006.440114
GO:0034191apolipoprotein A-I receptor binding1.15e-021.00e+006.440114
GO:0009301snRNA transcription1.15e-021.00e+006.440114
GO:0070940dephosphorylation of RNA polymerase II C-terminal domain1.15e-021.00e+006.440114
GO:0032463negative regulation of protein homooligomerization1.15e-021.00e+006.440114
GO:0051902negative regulation of mitochondrial depolarization1.15e-021.00e+006.440114
GO:0031062positive regulation of histone methylation1.15e-021.00e+006.440114
GO:0060684epithelial-mesenchymal cell signaling1.15e-021.00e+006.440114
GO:0070851growth factor receptor binding1.15e-021.00e+006.440114
GO:0051835positive regulation of synapse structural plasticity1.15e-021.00e+006.440114
GO:0090231regulation of spindle checkpoint1.15e-021.00e+006.440114
GO:0072384organelle transport along microtubule1.15e-021.00e+006.440124
GO:0007258JUN phosphorylation1.15e-021.00e+006.440114
GO:0048664neuron fate determination1.15e-021.00e+006.440114
GO:0033503HULC complex1.15e-021.00e+006.440114
GO:0031063regulation of histone deacetylation1.15e-021.00e+006.440114
GO:0031467Cul7-RING ubiquitin ligase complex1.15e-021.00e+006.440114
GO:0000055ribosomal large subunit export from nucleus1.15e-021.00e+006.440114
GO:0033625positive regulation of integrin activation1.15e-021.00e+006.440114
GO:0038095Fc-epsilon receptor signaling pathway1.31e-021.00e+002.60733171
GO:0006417regulation of translation1.42e-021.00e+003.4632463
GO:2000641regulation of early endosome to late endosome transport1.43e-021.00e+006.118115
GO:0070934CRD-mediated mRNA stabilization1.43e-021.00e+006.118115
GO:0036336dendritic cell migration1.43e-021.00e+006.118115
GO:0033033negative regulation of myeloid cell apoptotic process1.43e-021.00e+006.118115
GO:0035088establishment or maintenance of apical/basal cell polarity1.43e-021.00e+006.118115
GO:0051385response to mineralocorticoid1.43e-021.00e+006.118115
GO:0005826actomyosin contractile ring1.43e-021.00e+006.118115
GO:1902188positive regulation of viral release from host cell1.43e-021.00e+006.118115
GO:0097300programmed necrotic cell death1.43e-021.00e+006.118115
GO:0031256leading edge membrane1.43e-021.00e+006.118115
GO:0008420CTD phosphatase activity1.43e-021.00e+006.118115
GO:0031584activation of phospholipase D activity1.43e-021.00e+006.118115
GO:0009404toxin metabolic process1.43e-021.00e+006.118115
GO:0007049cell cycle1.43e-021.00e+002.55734177
GO:0071803positive regulation of podosome assembly1.43e-021.00e+006.118115
GO:0046834lipid phosphorylation1.43e-021.00e+006.118115
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.46e-021.00e+003.4402264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.50e-021.00e+003.4172665
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.50e-021.00e+003.4172665
GO:0019904protein domain specific binding1.52e-021.00e+002.52533181
GO:0003682chromatin binding1.54e-021.00e+002.05644334
GO:0071260cellular response to mechanical stimulus1.55e-021.00e+003.3952366
GO:0050847progesterone receptor signaling pathway1.72e-021.00e+005.855116
GO:0007143female meiotic division1.72e-021.00e+005.855116
GO:0002309T cell proliferation involved in immune response1.72e-021.00e+005.855116
GO:0045182translation regulator activity1.72e-021.00e+005.855126
GO:0004704NF-kappaB-inducing kinase activity1.72e-021.00e+005.855116
GO:0045056transcytosis1.72e-021.00e+005.855116
GO:0060789hair follicle placode formation1.72e-021.00e+005.855116
GO:0048554positive regulation of metalloenzyme activity1.72e-021.00e+005.855116
GO:0050792regulation of viral process1.72e-021.00e+005.855116
GO:0002181cytoplasmic translation1.72e-021.00e+005.855126
GO:0070937CRD-mediated mRNA stability complex1.72e-021.00e+005.855116
GO:0000974Prp19 complex1.72e-021.00e+005.855116
GO:0071204histone pre-mRNA 3'end processing complex1.72e-021.00e+005.855116
GO:0006924activation-induced cell death of T cells1.72e-021.00e+005.855126
GO:0001503ossification1.78e-021.00e+003.2902271
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.87e-021.00e+003.2502673
GO:0003729mRNA binding1.87e-021.00e+003.2502373
GO:0010447response to acidic pH2.00e-021.00e+005.632117
GO:0060136embryonic process involved in female pregnancy2.00e-021.00e+005.632117
GO:0043497regulation of protein heterodimerization activity2.00e-021.00e+005.632117
GO:0050658RNA transport2.00e-021.00e+005.632117
GO:0007097nuclear migration2.00e-021.00e+005.632127
GO:0061512protein localization to cilium2.00e-021.00e+005.632117
GO:0003334keratinocyte development2.00e-021.00e+005.632117
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.00e-021.00e+005.632117
GO:0000028ribosomal small subunit assembly2.00e-021.00e+005.632137
GO:0034101erythrocyte homeostasis2.00e-021.00e+005.632117
GO:0010907positive regulation of glucose metabolic process2.00e-021.00e+005.632117
GO:0048193Golgi vesicle transport2.00e-021.00e+005.632117
GO:0030157pancreatic juice secretion2.00e-021.00e+005.632117
GO:0000930gamma-tubulin complex2.00e-021.00e+005.632117
GO:0003924GTPase activity2.06e-021.00e+002.35936203
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.07e-021.00e+003.1732677
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.07e-021.00e+003.1732477
GO:0039702viral budding via host ESCRT complex2.28e-021.00e+005.440118
GO:0071222cellular response to lipopolysaccharide2.28e-021.00e+003.1002481
GO:0043114regulation of vascular permeability2.28e-021.00e+005.440118
GO:0045124regulation of bone resorption2.28e-021.00e+005.440118
GO:0051489regulation of filopodium assembly2.28e-021.00e+005.440118
GO:0033523histone H2B ubiquitination2.28e-021.00e+005.440118
GO:0007172signal complex assembly2.28e-021.00e+005.440118
GO:0006184GTP catabolic process2.54e-021.00e+002.24336220
GO:0016591DNA-directed RNA polymerase II, holoenzyme2.56e-021.00e+005.270119
GO:0038061NIK/NF-kappaB signaling2.56e-021.00e+005.270119
GO:0071732cellular response to nitric oxide2.56e-021.00e+005.270119
GO:0034067protein localization to Golgi apparatus2.56e-021.00e+005.270119
GO:0090136epithelial cell-cell adhesion2.56e-021.00e+005.270129
GO:0047497mitochondrion transport along microtubule2.56e-021.00e+005.270119
GO:0046628positive regulation of insulin receptor signaling pathway2.56e-021.00e+005.270119
GO:0008284positive regulation of cell proliferation2.60e-021.00e+001.82547392
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.65e-021.00e+001.56059589
GO:0050852T cell receptor signaling pathway2.66e-021.00e+002.9802288
GO:0000278mitotic cell cycle2.73e-021.00e+001.803416398
GO:0000187activation of MAPK activity2.77e-021.00e+002.9482390
GO:0032040small-subunit processome2.84e-021.00e+005.1181110
GO:0005798Golgi-associated vesicle2.84e-021.00e+005.1181110
GO:0031274positive regulation of pseudopodium assembly2.84e-021.00e+005.1181210
GO:0022407regulation of cell-cell adhesion2.84e-021.00e+005.1181110
GO:0060047heart contraction2.84e-021.00e+005.1181110
GO:0007067mitotic nuclear division2.87e-021.00e+002.17337231
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.00e-021.00e+002.8852794
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity3.12e-021.00e+004.9801111
GO:0051895negative regulation of focal adhesion assembly3.12e-021.00e+004.9801111
GO:0045120pronucleus3.12e-021.00e+004.9801111
GO:2000573positive regulation of DNA biosynthetic process3.12e-021.00e+004.9801211
GO:0060065uterus development3.12e-021.00e+004.9801111
GO:0010390histone monoubiquitination3.12e-021.00e+004.9801111
GO:0035518histone H2A monoubiquitination3.12e-021.00e+004.9801211
GO:0061136regulation of proteasomal protein catabolic process3.40e-021.00e+004.8551112
GO:0007051spindle organization3.40e-021.00e+004.8551112
GO:0043149stress fiber assembly3.40e-021.00e+004.8551212
GO:0043249erythrocyte maturation3.40e-021.00e+004.8551112
GO:1903543positive regulation of exosomal secretion3.40e-021.00e+004.8551112
GO:1901214regulation of neuron death3.40e-021.00e+004.8551112
GO:0005654nucleoplasm3.59e-021.00e+001.1507261095
GO:0031929TOR signaling3.68e-021.00e+004.7391113
GO:0005662DNA replication factor A complex3.68e-021.00e+004.7391113
GO:0071398cellular response to fatty acid3.68e-021.00e+004.7391213
GO:0060444branching involved in mammary gland duct morphogenesis3.68e-021.00e+004.7391113
GO:0004143diacylglycerol kinase activity3.68e-021.00e+004.7391113
GO:0035371microtubule plus-end3.96e-021.00e+004.6321114
GO:0031333negative regulation of protein complex assembly3.96e-021.00e+004.6321114
GO:0050662coenzyme binding3.96e-021.00e+004.6321114
GO:0017016Ras GTPase binding3.96e-021.00e+004.6321114
GO:0071480cellular response to gamma radiation3.96e-021.00e+004.6321114
GO:0031996thioesterase binding3.96e-021.00e+004.6321114
GO:0005634nucleus3.97e-021.00e+000.52520664828
GO:0005815microtubule organizing center4.00e-021.00e+002.65824110
GO:0048477oogenesis4.24e-021.00e+004.5331115
GO:0030131clathrin adaptor complex4.24e-021.00e+004.5331115
GO:0030225macrophage differentiation4.24e-021.00e+004.5331115
GO:0003951NAD+ kinase activity4.24e-021.00e+004.5331115
GO:0048821erythrocyte development4.24e-021.00e+004.5331215
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process4.24e-021.00e+004.5331115
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand4.24e-021.00e+004.5331115
GO:0031369translation initiation factor binding4.24e-021.00e+004.5331215
GO:0051233spindle midzone4.24e-021.00e+004.5331215
GO:0005762mitochondrial large ribosomal subunit4.24e-021.00e+004.5331115
GO:0014911positive regulation of smooth muscle cell migration4.51e-021.00e+004.4401116
GO:0048037cofactor binding4.51e-021.00e+004.4401116
GO:0042176regulation of protein catabolic process4.51e-021.00e+004.4401416
GO:2000811negative regulation of anoikis4.51e-021.00e+004.4401116
GO:0006006glucose metabolic process4.61e-021.00e+002.54524119
GO:0030742GTP-dependent protein binding4.79e-021.00e+004.3521117
GO:0070064proline-rich region binding5.06e-021.00e+004.2701118
GO:0004709MAP kinase kinase kinase activity5.06e-021.00e+004.2701118
GO:0031954positive regulation of protein autophosphorylation5.06e-021.00e+004.2701118
GO:0010507negative regulation of autophagy5.06e-021.00e+004.2701118
GO:0090316positive regulation of intracellular protein transport5.06e-021.00e+004.2701118
GO:0007264small GTPase mediated signal transduction5.08e-021.00e+001.84537290
GO:0006259DNA metabolic process5.33e-021.00e+004.1921119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.33e-021.00e+004.1921119
GO:0007088regulation of mitosis5.33e-021.00e+004.1921119
GO:0045453bone resorption5.33e-021.00e+004.1921119
GO:0031667response to nutrient levels5.33e-021.00e+004.1921119
GO:0009615response to virus5.54e-021.00e+002.39524132
GO:0032148activation of protein kinase B activity5.61e-021.00e+004.1181120
GO:0051090regulation of sequence-specific DNA binding transcription factor activity5.61e-021.00e+004.1181220
GO:0043473pigmentation5.61e-021.00e+004.1181220
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator5.61e-021.00e+004.1181120
GO:0043393regulation of protein binding5.61e-021.00e+004.1181220
GO:0007369gastrulation5.88e-021.00e+004.0481121
GO:0042474middle ear morphogenesis5.88e-021.00e+004.0481121
GO:0005689U12-type spliceosomal complex5.88e-021.00e+004.0481221
GO:0046847filopodium assembly5.88e-021.00e+004.0481121
GO:0051881regulation of mitochondrial membrane potential5.88e-021.00e+004.0481121
GO:2001243negative regulation of intrinsic apoptotic signaling pathway6.15e-021.00e+003.9801122
GO:0046686response to cadmium ion6.15e-021.00e+003.9801122
GO:0001106RNA polymerase II transcription corepressor activity6.15e-021.00e+003.9801122
GO:0031435mitogen-activated protein kinase kinase kinase binding6.15e-021.00e+003.9801122
GO:0007052mitotic spindle organization6.15e-021.00e+003.9801122
GO:1900026positive regulation of substrate adhesion-dependent cell spreading6.42e-021.00e+003.9161123
GO:0045787positive regulation of cell cycle6.42e-021.00e+003.9161223
GO:0002040sprouting angiogenesis6.42e-021.00e+003.9161123
GO:0051017actin filament bundle assembly6.42e-021.00e+003.9161123
GO:0001892embryonic placenta development6.42e-021.00e+003.9161123
GO:0051297centrosome organization6.42e-021.00e+003.9161223
GO:0008286insulin receptor signaling pathway6.46e-021.00e+002.27024144
GO:0008135translation factor activity, nucleic acid binding6.69e-021.00e+003.8551424
GO:0005761mitochondrial ribosome6.69e-021.00e+003.8551124
GO:0007163establishment or maintenance of cell polarity6.69e-021.00e+003.8551224
GO:0051602response to electrical stimulus6.69e-021.00e+003.8551124
GO:0005525GTP binding6.83e-021.00e+001.66736328
GO:0010628positive regulation of gene expression6.85e-021.00e+002.22124149
GO:0006611protein export from nucleus6.96e-021.00e+003.7961125
GO:0031519PcG protein complex6.96e-021.00e+003.7961125
GO:0050715positive regulation of cytokine secretion6.96e-021.00e+003.7961125
GO:0048705skeletal system morphogenesis6.96e-021.00e+003.7961125
GO:0043231intracellular membrane-bounded organelle7.02e-021.00e+001.65033332
GO:0042981regulation of apoptotic process7.02e-021.00e+002.20127151
GO:0045859regulation of protein kinase activity7.23e-021.00e+003.7391126
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway7.23e-021.00e+003.7391126
GO:0030148sphingolipid biosynthetic process7.23e-021.00e+003.7391126
GO:0010008endosome membrane7.50e-021.00e+002.14522157
GO:0051149positive regulation of muscle cell differentiation7.50e-021.00e+003.6851227
GO:0032720negative regulation of tumor necrosis factor production7.50e-021.00e+003.6851127
GO:2001238positive regulation of extrinsic apoptotic signaling pathway7.50e-021.00e+003.6851127
GO:0031424keratinization7.50e-021.00e+003.6851127
GO:0001103RNA polymerase II repressing transcription factor binding7.50e-021.00e+003.6851127
GO:0030331estrogen receptor binding7.50e-021.00e+003.6851127
GO:0045184establishment of protein localization7.50e-021.00e+003.6851227
GO:0031069hair follicle morphogenesis7.50e-021.00e+003.6851127
GO:0032467positive regulation of cytokinesis7.76e-021.00e+003.6321128
GO:0042626ATPase activity, coupled to transmembrane movement of substances7.76e-021.00e+003.6321128
GO:0019005SCF ubiquitin ligase complex8.03e-021.00e+003.5821129
GO:0034605cellular response to heat8.03e-021.00e+003.5821129
GO:0072686mitotic spindle8.03e-021.00e+003.5821129
GO:0000398mRNA splicing, via spliceosome8.17e-021.00e+002.07422165
GO:0007346regulation of mitotic cell cycle8.30e-021.00e+003.5331330
GO:0046875ephrin receptor binding8.30e-021.00e+003.5331230
GO:0042169SH2 domain binding8.30e-021.00e+003.5331130
GO:0031647regulation of protein stability8.30e-021.00e+003.5331130
GO:0040018positive regulation of multicellular organism growth8.30e-021.00e+003.5331130
GO:0010494cytoplasmic stress granule8.30e-021.00e+003.5331230
GO:0034220ion transmembrane transport8.34e-021.00e+002.05622167
GO:0070555response to interleukin-18.56e-021.00e+003.4861131
GO:0007093mitotic cell cycle checkpoint8.56e-021.00e+003.4861231
GO:0033572transferrin transport8.82e-021.00e+003.4401132
GO:0015992proton transport8.82e-021.00e+003.4401132
GO:0051219phosphoprotein binding8.82e-021.00e+003.4401432
GO:0032091negative regulation of protein binding9.09e-021.00e+003.3951133
GO:0005158insulin receptor binding9.09e-021.00e+003.3951233
GO:0033077T cell differentiation in thymus9.09e-021.00e+003.3951133
GO:0048812neuron projection morphogenesis9.09e-021.00e+003.3951133
GO:0004672protein kinase activity9.30e-021.00e+001.96424178
GO:0001890placenta development9.35e-021.00e+003.3521134
GO:0042692muscle cell differentiation9.35e-021.00e+003.3521234
GO:0051701interaction with host9.35e-021.00e+003.3521134
GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway9.61e-021.00e+003.3111135
GO:2001237negative regulation of extrinsic apoptotic signaling pathway9.61e-021.00e+003.3111135
GO:0006367transcription initiation from RNA polymerase II promoter9.83e-021.00e+001.91625184
GO:0030178negative regulation of Wnt signaling pathway9.87e-021.00e+003.2701136
GO:0071560cellular response to transforming growth factor beta stimulus9.87e-021.00e+003.2701136
GO:0016301kinase activity1.01e-011.00e+003.2301237
GO:0018107peptidyl-threonine phosphorylation1.01e-011.00e+003.2301137
GO:0032880regulation of protein localization1.01e-011.00e+003.2301137
GO:0001568blood vessel development1.04e-011.00e+003.1921238
GO:0050681androgen receptor binding1.04e-011.00e+003.1921238
GO:0097191extrinsic apoptotic signaling pathway1.04e-011.00e+003.1921338
GO:0045740positive regulation of DNA replication1.04e-011.00e+003.1921138
GO:0090382phagosome maturation1.04e-011.00e+003.1921138
GO:0051781positive regulation of cell division1.06e-011.00e+003.1541139
GO:0008047enzyme activator activity1.06e-011.00e+003.1541139
GO:0032092positive regulation of protein binding1.06e-011.00e+003.1541139
GO:0042542response to hydrogen peroxide1.09e-011.00e+003.1181140
GO:0070301cellular response to hydrogen peroxide1.12e-011.00e+003.0821141
GO:0030521androgen receptor signaling pathway1.12e-011.00e+003.0821341
GO:0045785positive regulation of cell adhesion1.12e-011.00e+003.0821141
GO:0000139Golgi membrane1.13e-011.00e+001.35237408
GO:0042147retrograde transport, endosome to Golgi1.14e-011.00e+003.0481142
GO:0005902microvillus1.14e-011.00e+003.0481142
GO:0004715non-membrane spanning protein tyrosine kinase activity1.14e-011.00e+003.0481142
GO:0005794Golgi apparatus1.16e-011.00e+001.09648650
GO:0007286spermatid development1.19e-011.00e+002.9801144
GO:0005080protein kinase C binding1.19e-011.00e+002.9801144
GO:0034613cellular protein localization1.19e-011.00e+002.9801244
GO:0001701in utero embryonic development1.22e-011.00e+001.72622210
GO:0009411response to UV1.22e-011.00e+002.9481245
GO:0044297cell body1.24e-011.00e+002.9161146
GO:0043525positive regulation of neuron apoptotic process1.24e-011.00e+002.9161246
GO:0045727positive regulation of translation1.24e-011.00e+002.9161146
GO:0021762substantia nigra development1.24e-011.00e+002.9161246
GO:0043406positive regulation of MAP kinase activity1.27e-011.00e+002.8851147
GO:0008344adult locomotory behavior1.27e-011.00e+002.8851247
GO:0006950response to stress1.29e-011.00e+002.8551148
GO:0019003GDP binding1.29e-011.00e+002.8551148
GO:0005765lysosomal membrane1.30e-011.00e+001.67222218
GO:0005070SH3/SH2 adaptor activity1.32e-011.00e+002.8251149
GO:0022625cytosolic large ribosomal subunit1.32e-011.00e+002.8251149
GO:0003743translation initiation factor activity1.32e-011.00e+002.8251549
GO:0090263positive regulation of canonical Wnt signaling pathway1.37e-011.00e+002.7671151
GO:0030900forebrain development1.37e-011.00e+002.7671151
GO:0008202steroid metabolic process1.39e-011.00e+002.7391152
GO:0006952defense response1.42e-011.00e+002.7121153
GO:0030175filopodium1.42e-011.00e+002.7121253
GO:0019221cytokine-mediated signaling pathway1.42e-011.00e+001.59425230
GO:0009612response to mechanical stimulus1.44e-011.00e+002.6851154
GO:0000186activation of MAPKK activity1.44e-011.00e+002.6851154
GO:0097193intrinsic apoptotic signaling pathway1.47e-011.00e+002.6581255
GO:0002039p53 binding1.47e-011.00e+002.6581155
GO:0046330positive regulation of JNK cascade1.47e-011.00e+002.6581155
GO:0006468protein phosphorylation1.51e-011.00e+001.15836467
GO:0005793endoplasmic reticulum-Golgi intermediate compartment1.52e-011.00e+002.6071157
GO:0006879cellular iron ion homeostasis1.52e-011.00e+002.6071257
GO:0005643nuclear pore1.57e-011.00e+002.5571159
GO:0033138positive regulation of peptidyl-serine phosphorylation1.62e-011.00e+002.5091161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.64e-011.00e+002.4861162
GO:0045893positive regulation of transcription, DNA-templated1.65e-011.00e+001.09738487
GO:0000151ubiquitin ligase complex1.66e-011.00e+002.4631163
GO:0005901caveola1.66e-011.00e+002.4631163
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process1.66e-011.00e+002.4631263
GO:0043025neuronal cell body1.66e-011.00e+001.45125254
GO:0004842ubiquitin-protein transferase activity1.68e-011.00e+001.44023256
GO:0007059chromosome segregation1.69e-011.00e+002.4401364
GO:0032869cellular response to insulin stimulus1.69e-011.00e+002.4401264
GO:0016491oxidoreductase activity1.71e-011.00e+002.4171165
GO:0005882intermediate filament1.74e-011.00e+002.3951366
GO:0030141secretory granule1.76e-011.00e+002.3741267
GO:0006281DNA repair1.76e-011.00e+001.39525264
GO:0006665sphingolipid metabolic process1.78e-011.00e+002.3521168
GO:0003697single-stranded DNA binding1.81e-011.00e+002.3311469
GO:0005739mitochondrion1.81e-011.00e+000.7315101046
GO:0035264multicellular organism growth1.83e-011.00e+002.3111170
GO:0055085transmembrane transport1.84e-011.00e+001.01933514
GO:0000166nucleotide binding1.84e-011.00e+001.35222272
GO:0042393histone binding1.86e-011.00e+002.2901171
GO:0005975carbohydrate metabolic process1.87e-011.00e+001.34223274
GO:0000165MAPK cascade1.88e-011.00e+002.2701272
GO:0000785chromatin1.90e-011.00e+002.2501273
GO:0042826histone deacetylase binding1.93e-011.00e+002.2301174
GO:0007265Ras protein signal transduction1.95e-011.00e+002.2111375
GO:0051897positive regulation of protein kinase B signaling1.95e-011.00e+002.2111175
GO:0060070canonical Wnt signaling pathway1.95e-011.00e+002.2111275
GO:0044325ion channel binding2.00e-011.00e+002.1731377
GO:0008584male gonad development2.00e-011.00e+002.1731177
GO:0019899enzyme binding2.01e-011.00e+001.27025288
GO:0007229integrin-mediated signaling pathway2.02e-011.00e+002.1541278
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.04e-011.00e+000.776411811
GO:0071013catalytic step 2 spliceosome2.04e-011.00e+002.1361179
GO:0010629negative regulation of gene expression2.06e-011.00e+002.1181280
GO:0031902late endosome membrane2.06e-011.00e+002.1181180
GO:0051301cell division2.09e-011.00e+002.1001281
GO:0045177apical part of cell2.11e-011.00e+002.0821182
GO:0004713protein tyrosine kinase activity2.11e-011.00e+002.0821182
GO:0030336negative regulation of cell migration2.13e-011.00e+002.0651283
GO:0043234protein complex2.14e-011.00e+001.21129300
GO:0005929cilium2.16e-011.00e+002.0481284
GO:0005179hormone activity2.16e-011.00e+002.0481184
GO:0006915apoptotic process2.26e-011.00e+000.86739571
GO:0042593glucose homeostasis2.27e-011.00e+001.9641189
GO:0004674protein serine/threonine kinase activity2.27e-011.00e+001.15426312
GO:0042384cilium assembly2.29e-011.00e+001.9481290
GO:0000922spindle pole2.31e-011.00e+001.9321591
GO:0003690double-stranded DNA binding2.31e-011.00e+001.9321291
GO:0035556intracellular signal transduction2.32e-011.00e+001.13225317
GO:0016337single organismal cell-cell adhesion2.34e-011.00e+001.9161292
GO:0016363nuclear matrix2.34e-011.00e+001.9161492
GO:0042470melanosome2.34e-011.00e+001.9161292
GO:0019901protein kinase binding2.35e-011.00e+001.11829320
GO:0005770late endosome2.38e-011.00e+001.8851194
GO:0007010cytoskeleton organization2.42e-011.00e+001.8551196
GO:0007411axon guidance2.43e-011.00e+001.08723327
GO:0005178integrin binding2.45e-011.00e+001.8401197
GO:0008283cell proliferation2.47e-011.00e+001.06924331
GO:0016568chromatin modification2.49e-011.00e+001.8101299
GO:0005813centrosome2.55e-011.00e+001.03529339
GO:0014069postsynaptic density2.64e-011.00e+001.71213106
GO:0030496midbody2.70e-011.00e+001.67214109
GO:0070374positive regulation of ERK1 and ERK2 cascade2.73e-011.00e+001.65811110
GO:0050900leukocyte migration2.75e-011.00e+001.64511111
GO:0020037heme binding2.75e-011.00e+001.64511111
GO:0007605sensory perception of sound2.75e-011.00e+001.64511111
GO:0015630microtubule cytoskeleton2.77e-011.00e+001.63214112
GO:0005819spindle2.81e-011.00e+001.60714114
GO:0005802trans-Golgi network2.85e-011.00e+001.58212116
GO:0032496response to lipopolysaccharide2.98e-011.00e+001.50911122
GO:0001501skeletal system development3.00e-011.00e+001.49711123
GO:0051056regulation of small GTPase mediated signal transduction3.00e-011.00e+001.49713123
GO:0006511ubiquitin-dependent protein catabolic process3.08e-011.00e+001.45113127
GO:0030036actin cytoskeleton organization3.12e-011.00e+001.42913129
GO:0046983protein dimerization activity3.16e-011.00e+001.40613131
GO:0018108peptidyl-tyrosine phosphorylation3.20e-011.00e+001.38511133
GO:0016055Wnt signaling pathway3.35e-011.00e+001.30013141
GO:0005911cell-cell junction3.37e-011.00e+001.29012142
GO:0006366transcription from RNA polymerase II promoter3.47e-011.00e+000.70923425
GO:0005524ATP binding3.50e-011.00e+000.3595191354
GO:0006974cellular response to DNA damage stimulus3.67e-011.00e+001.13613158
GO:0046777protein autophosphorylation3.67e-011.00e+001.13611158
GO:0008022protein C-terminus binding3.73e-011.00e+001.10914161
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding3.86e-011.00e+001.04814168
GO:0007596blood coagulation3.88e-011.00e+000.58225464
GO:0007420brain development3.93e-011.00e+001.01413172
GO:0016607nuclear speck3.98e-011.00e+000.98912175
GO:0031965nuclear membrane4.00e-011.00e+000.98012176
GO:0031625ubiquitin protein ligase binding4.07e-011.00e+000.94814180
GO:0005764lysosome4.10e-011.00e+000.93212182
GO:0048471perinuclear region of cytoplasm4.47e-011.00e+000.40929523
GO:0030168platelet activation4.48e-011.00e+000.76014205
GO:0004871signal transducer activity4.66e-011.00e+000.68511216
GO:0016874ligase activity4.78e-011.00e+000.63212224
GO:0006351transcription, DNA-templated4.86e-011.00e+000.1325171585
GO:0008380RNA splicing4.90e-011.00e+000.58215232
GO:0030425dendrite5.02e-011.00e+000.53313240
GO:0044281small molecule metabolic process5.18e-011.00e+000.1014161295
GO:0007165signal transduction5.21e-011.00e+000.13337950
GO:0005102receptor binding5.41e-011.00e+000.37412268
GO:0003779actin binding5.51e-011.00e+000.33713275
GO:0007283spermatogenesis5.52e-011.00e+000.33112276
GO:0042493response to drug5.67e-011.00e+000.27012288
GO:0016567protein ubiquitination5.81e-011.00e+000.21613299
GO:0005743mitochondrial inner membrane5.82e-011.00e+000.21111300
GO:0006955immune response5.88e-011.00e+000.18712305
GO:0005856cytoskeleton5.96e-011.00e+000.15916311
GO:0005575cellular_component6.09e-011.00e+000.10912322
GO:0046872metal ion binding6.19e-011.00e+00-0.0774141465
GO:0006355regulation of transcription, DNA-templated6.25e-011.00e+00-0.0843101104
GO:0007275multicellular organismal development6.33e-011.00e+000.01412344
GO:0003700sequence-specific DNA binding transcription factor activity6.41e-011.00e+00-0.10729748
GO:0015031protein transport6.47e-011.00e+00-0.04014357
GO:0008285negative regulation of cell proliferation6.57e-011.00e+00-0.08013367
GO:0007155cell adhesion6.74e-011.00e+00-0.14513384
GO:0045892negative regulation of transcription, DNA-templated7.10e-011.00e+00-0.28812424
GO:0008150biological_process7.39e-011.00e+00-0.40213459
GO:0055114oxidation-reduction process7.55e-011.00e+00-0.47012481
GO:0003677DNA binding7.58e-011.00e+00-0.3753141351
GO:0042802identical protein binding7.63e-011.00e+00-0.50014491
GO:0008270zinc ion binding8.22e-011.00e+00-0.619271067
GO:0005783endoplasmic reticulum8.34e-011.00e+00-0.81316610
GO:0005886plasma membrane8.49e-011.00e+00-0.4446242834
GO:0005887integral component of plasma membrane9.43e-011.00e+00-1.46912961
GO:0005615extracellular space9.51e-011.00e+00-1.540131010