Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
tai-screen-luciferase | 6.375 | 2.94e-136 | 3.59e-07 | 2.58e-03 |
Gene Symbol | Entrez Gene ID | Frequency | tai-screen-luciferase gene score | Best subnetwork score | Degree | List-Gonzales GI | Tai-Hits |
---|---|---|---|---|---|---|---|
RPS8 | 6202 | 10 | -5.545 | 7.555 | 234 | - | - |
CHMP2A | 27243 | 10 | -9.037 | 7.555 | 41 | Yes | Yes |
RPS15 | 6209 | 7 | -5.040 | 7.011 | 116 | Yes | - |
COPA | 1314 | 32 | -9.395 | 9.063 | 170 | Yes | Yes |
RPS24 | 6229 | 21 | -7.034 | 8.389 | 217 | Yes | - |
RPS9 | 6203 | 18 | -7.127 | 7.555 | 140 | Yes | - |
COPB2 | 9276 | 32 | -13.168 | 9.063 | 41 | Yes | Yes |
RPS4X | 6191 | 18 | -6.747 | 7.555 | 263 | Yes | - |
COPZ1 | 22818 | 32 | -8.301 | 9.063 | 13 | Yes | Yes |
ATP6V1D | 51382 | 8 | -4.131 | 7.286 | 149 | - | - |
RPS16 | 6217 | 5 | -5.444 | 7.011 | 202 | - | - |
WDR46 | 9277 | 3 | -4.290 | 7.486 | 87 | Yes | Yes |
RPS15A | 6210 | 8 | -5.413 | 7.555 | 177 | Yes | - |
RPS27A | 6233 | 15 | -5.631 | 8.389 | 342 | Yes | - |
RPS11 | 6205 | 17 | -6.588 | 7.555 | 175 | Yes | - |
RPS6 | 6194 | 17 | -5.603 | 8.046 | 208 | Yes | - |
MRPS12 | 6183 | 1 | -5.421 | 6.375 | 34 | Yes | - |
SKP1 | 6500 | 4 | -3.750 | 6.413 | 203 | - | - |
RAN | 5901 | 4 | -3.809 | 6.905 | 175 | Yes | Yes |
[ SPHK2 ] | 56848 | 1 | -3.010 | 6.375 | 37 | - | - |
RPS26 | 6231 | 17 | -7.478 | 8.046 | 60 | Yes | - |
ARCN1 | 372 | 32 | -8.232 | 9.063 | 118 | Yes | Yes |
COPB1 | 1315 | 22 | -6.221 | 9.063 | 118 | Yes | Yes |
RPS13 | 6207 | 17 | -6.589 | 7.555 | 174 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
RPS8 | 6202 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RAN | 5901 | RPS11 | 6205 | pp | -- | int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE |
RPS4X | 6191 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS8 | 6202 | RPS9 | 6203 | pp | -- | int.I2D: BioGrid_Yeast |
RPS15 | 6209 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium |
COPA | 1314 | COPB1 | 1315 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh |
RAN | 5901 | SPHK2 | 56848 | pp | -- | int.I2D: IntAct_Yeast, BIND_Yeast, MINT_Yeast, MIPS, YeastLow |
RPS9 | 6203 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | RAN | 5901 | pp | -- | int.I2D: YeastLow |
RPS4X | 6191 | RPS8 | 6202 | pp | -- | int.I2D: BioGrid_Yeast |
RAN | 5901 | SKP1 | 6500 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPA | 1314 | pp | -- | int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo |
RPS15 | 6209 | RPS15A | 6210 | pp | -- | int.I2D: YeastMedium, INTEROLOG |
RPS4X | 6191 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG |
COPA | 1314 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo |
RPS11 | 6205 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | RPS15 | 6209 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
RPS8 | 6202 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | WDR46 | 9277 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS8 | 6202 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
COPA | 1314 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium |
RPS11 | 6205 | RPS15 | 6209 | pp | -- | int.I2D: INTEROLOG, YeastMedium |
COPA | 1314 | ATP6V1D | 51382 | pp | -- | int.I2D: YeastLow |
RPS13 | 6207 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium |
SKP1 | 6500 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPS6 | 6194 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS9 | 6203 | pp | -- | int.I2D: BioGrid_Yeast |
RPS15A | 6210 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
RPS6 | 6194 | RPS15 | 6209 | pp | -- | int.I2D: BioGrid_Yeast |
MRPS12 | 6183 | RPS15 | 6209 | pp | -- | int.I2D: YeastMedium |
RPS8 | 6202 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
RAN | 5901 | ATP6V1D | 51382 | pp | -- | int.I2D: YeastLow |
RPS11 | 6205 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPB1 | 1315 | pp | -- | int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo |
RPS8 | 6202 | SKP1 | 6500 | pp | -- | int.I2D: BioGrid_Yeast |
RPS15A | 6210 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS26 | 6231 | pp | -- | int.I2D: YeastLow |
COPA | 1314 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
RPS6 | 6194 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS16 | 6217 | RPS26 | 6231 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
RAN | 5901 | RPS15 | 6209 | pp | -- | int.I2D: YeastLow |
RPS6 | 6194 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
RPS16 | 6217 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS6 | 6194 | pp | -- | int.I2D: BioGrid_Yeast |
RPS15 | 6209 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS24 | 6229 | ATP6V1D | 51382 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS15A | 6210 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPB2 | 9276 | pp | -- | int.I2D: HPRD, BCI; int.HPRD: in vivo |
RAN | 5901 | WDR46 | 9277 | pp | -- | int.I2D: YeastLow |
RPS8 | 6202 | CHMP2A | 27243 | pp | -- | int.I2D: BioGrid_Yeast |
RPS8 | 6202 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS16 | 6217 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS15 | 6209 | pp | -- | int.I2D: INTEROLOG, YeastMedium |
RPS27A | 6233 | SKP1 | 6500 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
COPB1 | 1315 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid |
RPS4X | 6191 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG |
RPS8 | 6202 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS24 | 6229 | RPS27A | 6233 | pp | -- | int.I2D: YeastMedium |
COPB1 | 1315 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association) |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0022627 | cytosolic small ribosomal subunit | 6.15e-26 | 8.87e-22 | 7.531 | 12 | 20 | 39 |
GO:0019058 | viral life cycle | 3.40e-24 | 4.91e-20 | 6.193 | 14 | 23 | 115 |
GO:0019083 | viral transcription | 1.08e-21 | 1.55e-17 | 6.476 | 12 | 20 | 81 |
GO:0006415 | translational termination | 2.69e-21 | 3.88e-17 | 6.373 | 12 | 20 | 87 |
GO:0006414 | translational elongation | 6.28e-21 | 9.06e-17 | 6.277 | 12 | 20 | 93 |
GO:0003735 | structural constituent of ribosome | 6.54e-21 | 9.44e-17 | 5.834 | 13 | 22 | 137 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 2.59e-20 | 3.73e-16 | 6.116 | 12 | 20 | 104 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 8.20e-20 | 1.18e-15 | 5.983 | 12 | 20 | 114 |
GO:0006413 | translational initiation | 4.65e-19 | 6.70e-15 | 5.783 | 12 | 21 | 131 |
GO:0016032 | viral process | 5.60e-18 | 8.07e-14 | 4.170 | 16 | 33 | 534 |
GO:0006412 | translation | 6.56e-18 | 9.46e-14 | 5.086 | 13 | 23 | 230 |
GO:0015935 | small ribosomal subunit | 2.59e-16 | 3.74e-12 | 7.951 | 7 | 9 | 17 |
GO:0016071 | mRNA metabolic process | 3.19e-16 | 4.60e-12 | 5.015 | 12 | 25 | 223 |
GO:0016070 | RNA metabolic process | 1.10e-15 | 1.58e-11 | 4.868 | 12 | 25 | 247 |
GO:0005829 | cytosol | 3.10e-15 | 4.48e-11 | 2.405 | 22 | 61 | 2496 |
GO:0016020 | membrane | 3.99e-14 | 5.75e-10 | 2.764 | 19 | 41 | 1681 |
GO:0044822 | poly(A) RNA binding | 2.57e-13 | 3.71e-09 | 3.187 | 16 | 32 | 1056 |
GO:0044267 | cellular protein metabolic process | 2.61e-12 | 3.77e-08 | 3.927 | 12 | 23 | 474 |
GO:0010467 | gene expression | 6.39e-12 | 9.21e-08 | 3.546 | 13 | 29 | 669 |
GO:0030126 | COPI vesicle coat | 6.43e-12 | 9.27e-08 | 7.968 | 5 | 7 | 12 |
GO:0048205 | COPI coating of Golgi vesicle | 1.04e-11 | 1.50e-07 | 7.853 | 5 | 8 | 13 |
GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | 4.25e-10 | 6.13e-06 | 6.909 | 5 | 8 | 25 |
GO:0061024 | membrane organization | 2.69e-09 | 3.88e-05 | 4.859 | 7 | 12 | 145 |
GO:0042274 | ribosomal small subunit biogenesis | 2.89e-09 | 4.17e-05 | 7.646 | 4 | 6 | 12 |
GO:0005925 | focal adhesion | 1.53e-06 | 2.20e-02 | 3.523 | 7 | 19 | 366 |
GO:0005840 | ribosome | 2.36e-06 | 3.40e-02 | 5.373 | 4 | 8 | 58 |
GO:0006891 | intra-Golgi vesicle-mediated transport | 2.71e-06 | 3.91e-02 | 6.729 | 3 | 4 | 17 |
GO:0070062 | extracellular vesicular exosome | 4.45e-06 | 6.42e-02 | 1.810 | 14 | 40 | 2400 |
GO:0006886 | intracellular protein transport | 7.82e-06 | 1.13e-01 | 4.135 | 5 | 7 | 171 |
GO:0000056 | ribosomal small subunit export from nucleus | 7.95e-06 | 1.15e-01 | 8.646 | 2 | 2 | 3 |
GO:0019843 | rRNA binding | 1.15e-05 | 1.66e-01 | 6.061 | 3 | 4 | 27 |
GO:0006364 | rRNA processing | 1.63e-05 | 2.35e-01 | 4.677 | 4 | 7 | 94 |
GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.65e-05 | 3.82e-01 | 7.909 | 2 | 3 | 5 |
GO:0033119 | negative regulation of RNA splicing | 2.65e-05 | 3.82e-01 | 7.909 | 2 | 2 | 5 |
GO:0030529 | ribonucleoprotein complex | 3.25e-05 | 4.68e-01 | 4.424 | 4 | 7 | 112 |
GO:0075733 | intracellular transport of virus | 3.55e-04 | 1.00e+00 | 6.144 | 2 | 3 | 17 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 6.01e-04 | 1.00e+00 | 5.772 | 2 | 3 | 22 |
GO:0005844 | polysome | 6.57e-04 | 1.00e+00 | 5.708 | 2 | 2 | 23 |
GO:0033176 | proton-transporting V-type ATPase complex | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 1 |
GO:0021691 | cerebellar Purkinje cell layer maturation | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 1 |
GO:0006669 | sphinganine-1-phosphate biosynthetic process | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 1 |
GO:0022605 | oogenesis stage | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 1 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.87e-03 | 1.00e+00 | 3.597 | 3 | 9 | 149 |
GO:0005198 | structural molecule activity | 1.90e-03 | 1.00e+00 | 3.587 | 3 | 6 | 150 |
GO:0017050 | D-erythro-sphingosine kinase activity | 3.33e-03 | 1.00e+00 | 8.231 | 1 | 1 | 2 |
GO:0008481 | sphinganine kinase activity | 3.33e-03 | 1.00e+00 | 8.231 | 1 | 1 | 2 |
GO:0008284 | positive regulation of cell proliferation | 3.38e-03 | 1.00e+00 | 2.654 | 4 | 7 | 382 |
GO:0016197 | endosomal transport | 4.01e-03 | 1.00e+00 | 4.398 | 2 | 3 | 57 |
GO:0006670 | sphingosine metabolic process | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 3 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.98e-03 | 1.00e+00 | 4.102 | 2 | 8 | 70 |
GO:0003729 | mRNA binding | 6.32e-03 | 1.00e+00 | 4.061 | 2 | 2 | 72 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 4 |
GO:0000055 | ribosomal large subunit export from nucleus | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 4 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.66e-03 | 1.00e+00 | 4.022 | 2 | 8 | 74 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 7.56e-03 | 1.00e+00 | 3.927 | 2 | 8 | 79 |
GO:1902188 | positive regulation of viral release from host cell | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 5 |
GO:0046834 | lipid phosphorylation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 5 |
GO:0061512 | protein localization to cilium | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 6 |
GO:0002309 | T cell proliferation involved in immune response | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 6 |
GO:0045182 | translation regulator activity | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 6 |
GO:0006924 | activation-induced cell death of T cells | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 6 |
GO:0050792 | regulation of viral process | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 6 |
GO:0001649 | osteoblast differentiation | 1.01e-02 | 1.00e+00 | 3.708 | 2 | 3 | 92 |
GO:0030157 | pancreatic juice secretion | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 7 |
GO:0000028 | ribosomal small subunit assembly | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 3 | 7 |
GO:0034101 | erythrocyte homeostasis | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 7 |
GO:0039702 | viral budding via host ESCRT complex | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 8 |
GO:0005798 | Golgi-associated vesicle | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 10 |
GO:0007219 | Notch signaling pathway | 1.68e-02 | 1.00e+00 | 3.324 | 2 | 3 | 120 |
GO:0035518 | histone H2A monoubiquitination | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 11 |
GO:1903543 | positive regulation of exosomal secretion | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 12 |
GO:0019082 | viral protein processing | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 2 | 12 |
GO:0000086 | G2/M transition of mitotic cell cycle | 2.13e-02 | 1.00e+00 | 3.144 | 2 | 5 | 136 |
GO:0031929 | TOR signaling | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 13 |
GO:0032479 | regulation of type I interferon production | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 2 | 13 |
GO:0004143 | diacylglycerol kinase activity | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 13 |
GO:0008286 | insulin receptor signaling pathway | 2.31e-02 | 1.00e+00 | 3.081 | 2 | 3 | 142 |
GO:0017016 | Ras GTPase binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 14 |
GO:0030131 | clathrin adaptor complex | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 14 |
GO:0031369 | translation initiation factor binding | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 15 |
GO:0048821 | erythrocyte development | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 15 |
GO:0003951 | NAD+ kinase activity | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 1 | 15 |
GO:0019068 | virion assembly | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 17 |
GO:0006259 | DNA metabolic process | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 19 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 19 |
GO:0007369 | gastrulation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 19 |
GO:0043066 | negative regulation of apoptotic process | 3.23e-02 | 1.00e+00 | 2.088 | 3 | 13 | 424 |
GO:0043473 | pigmentation | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 1 | 20 |
GO:0019904 | protein domain specific binding | 3.54e-02 | 1.00e+00 | 2.747 | 2 | 3 | 179 |
GO:0007220 | Notch receptor processing | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 22 |
GO:0045787 | positive regulation of cell cycle | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 22 |
GO:0005761 | mitochondrial ribosome | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 1 | 22 |
GO:0007052 | mitotic spindle organization | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 1 | 22 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 2 | 25 |
GO:0006611 | protein export from nucleus | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 1 | 25 |
GO:0031519 | PcG protein complex | 4.08e-02 | 1.00e+00 | 4.587 | 1 | 1 | 25 |
GO:0030148 | sphingolipid biosynthetic process | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 1 | 26 |
GO:0005978 | glycogen biosynthetic process | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 2 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 2 | 26 |
GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 1 | 26 |
GO:0045184 | establishment of protein localization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 27 |
GO:0005765 | lysosomal membrane | 4.44e-02 | 1.00e+00 | 2.566 | 2 | 2 | 203 |
GO:0019005 | SCF ubiquitin ligase complex | 4.72e-02 | 1.00e+00 | 4.373 | 1 | 1 | 29 |
GO:0015992 | proton transport | 4.72e-02 | 1.00e+00 | 4.373 | 1 | 1 | 29 |
GO:0033572 | transferrin transport | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 1 | 30 |
GO:0001890 | placenta development | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 1 | 31 |
GO:0007093 | mitotic cell cycle checkpoint | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 1 | 31 |
GO:0051701 | interaction with host | 5.20e-02 | 1.00e+00 | 4.231 | 1 | 1 | 32 |
GO:0032480 | negative regulation of type I interferon production | 5.20e-02 | 1.00e+00 | 4.231 | 1 | 2 | 32 |
GO:0033077 | T cell differentiation in thymus | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 1 | 33 |
GO:0007067 | mitotic nuclear division | 5.43e-02 | 1.00e+00 | 2.405 | 2 | 5 | 227 |
GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 1 | 35 |
GO:0001568 | blood vessel development | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 1 | 35 |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 3 | 36 |
GO:0090382 | phagosome maturation | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 1 | 36 |
GO:0032092 | positive regulation of protein binding | 6.14e-02 | 1.00e+00 | 3.983 | 1 | 1 | 38 |
GO:0050681 | androgen receptor binding | 6.14e-02 | 1.00e+00 | 3.983 | 1 | 1 | 38 |
GO:0007286 | spermatid development | 6.61e-02 | 1.00e+00 | 3.874 | 1 | 1 | 41 |
GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 6.61e-02 | 1.00e+00 | 3.874 | 1 | 3 | 41 |
GO:0030521 | androgen receptor signaling pathway | 6.61e-02 | 1.00e+00 | 3.874 | 1 | 1 | 41 |
GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | 6.92e-02 | 1.00e+00 | 3.805 | 1 | 2 | 43 |
GO:0045727 | positive regulation of translation | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 1 | 44 |
GO:0008344 | adult locomotory behavior | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 1 | 44 |
GO:0005737 | cytoplasm | 7.09e-02 | 1.00e+00 | 0.674 | 10 | 43 | 3767 |
GO:0043065 | positive regulation of apoptotic process | 7.26e-02 | 1.00e+00 | 2.165 | 2 | 6 | 268 |
GO:0044297 | cell body | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 1 | 46 |
GO:0019003 | GDP binding | 7.54e-02 | 1.00e+00 | 3.677 | 1 | 2 | 47 |
GO:0005515 | protein binding | 7.59e-02 | 1.00e+00 | 0.482 | 14 | 62 | 6024 |
GO:0007254 | JNK cascade | 7.85e-02 | 1.00e+00 | 3.616 | 1 | 3 | 49 |
GO:0006879 | cellular iron ion homeostasis | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 1 | 51 |
GO:0030666 | endocytic vesicle membrane | 8.46e-02 | 1.00e+00 | 3.503 | 1 | 2 | 53 |
GO:0051403 | stress-activated MAPK cascade | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 3 | 54 |
GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment | 8.92e-02 | 1.00e+00 | 3.424 | 1 | 1 | 56 |
GO:0005643 | nuclear pore | 9.07e-02 | 1.00e+00 | 3.398 | 1 | 1 | 57 |
GO:0006665 | sphingolipid metabolic process | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 1 | 60 |
GO:0032481 | positive regulation of type I interferon production | 9.68e-02 | 1.00e+00 | 3.300 | 1 | 3 | 61 |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 9.68e-02 | 1.00e+00 | 3.300 | 1 | 2 | 61 |
GO:0043231 | intracellular membrane-bounded organelle | 9.74e-02 | 1.00e+00 | 1.918 | 2 | 5 | 318 |
GO:0006417 | regulation of translation | 9.83e-02 | 1.00e+00 | 3.277 | 1 | 2 | 62 |
GO:0005654 | nucleoplasm | 1.01e-01 | 1.00e+00 | 1.152 | 4 | 15 | 1082 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.01e-01 | 1.00e+00 | 3.231 | 1 | 6 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 6 | 65 |
GO:0034146 | toll-like receptor 5 signaling pathway | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 4 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 4 | 65 |
GO:0003723 | RNA binding | 1.10e-01 | 1.00e+00 | 1.813 | 2 | 8 | 342 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 1.12e-01 | 1.00e+00 | 3.081 | 1 | 4 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 1.12e-01 | 1.00e+00 | 3.081 | 1 | 4 | 71 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.13e-01 | 1.00e+00 | 3.061 | 1 | 6 | 72 |
GO:0034162 | toll-like receptor 9 signaling pathway | 1.13e-01 | 1.00e+00 | 3.061 | 1 | 4 | 72 |
GO:0034134 | toll-like receptor 2 signaling pathway | 1.15e-01 | 1.00e+00 | 3.041 | 1 | 4 | 73 |
GO:0000785 | chromatin | 1.15e-01 | 1.00e+00 | 3.041 | 1 | 1 | 73 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 6 | 75 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 4 | 76 |
GO:0031902 | late endosome membrane | 1.21e-01 | 1.00e+00 | 2.964 | 1 | 2 | 77 |
GO:0005929 | cilium | 1.21e-01 | 1.00e+00 | 2.964 | 1 | 1 | 77 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 4 | 78 |
GO:0005179 | hormone activity | 1.24e-01 | 1.00e+00 | 2.927 | 1 | 1 | 79 |
GO:0034138 | toll-like receptor 3 signaling pathway | 1.24e-01 | 1.00e+00 | 2.927 | 1 | 4 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 1.25e-01 | 1.00e+00 | 2.909 | 1 | 4 | 80 |
GO:0005730 | nucleolus | 1.29e-01 | 1.00e+00 | 0.873 | 5 | 24 | 1641 |
GO:0050852 | T cell receptor signaling pathway | 1.32e-01 | 1.00e+00 | 2.822 | 1 | 2 | 85 |
GO:0042384 | cilium assembly | 1.34e-01 | 1.00e+00 | 2.805 | 1 | 1 | 86 |
GO:0042593 | glucose homeostasis | 1.35e-01 | 1.00e+00 | 2.788 | 1 | 1 | 87 |
GO:0000278 | mitotic cell cycle | 1.37e-01 | 1.00e+00 | 1.620 | 2 | 11 | 391 |
GO:0000187 | activation of MAPK activity | 1.40e-01 | 1.00e+00 | 2.739 | 1 | 2 | 90 |
GO:0042470 | melanosome | 1.41e-01 | 1.00e+00 | 2.723 | 1 | 2 | 91 |
GO:0071456 | cellular response to hypoxia | 1.42e-01 | 1.00e+00 | 2.708 | 1 | 3 | 92 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.42e-01 | 1.00e+00 | 2.708 | 1 | 6 | 92 |
GO:0034142 | toll-like receptor 4 signaling pathway | 1.48e-01 | 1.00e+00 | 2.646 | 1 | 4 | 96 |
GO:0055085 | transmembrane transport | 1.63e-01 | 1.00e+00 | 1.466 | 2 | 3 | 435 |
GO:0002224 | toll-like receptor signaling pathway | 1.67e-01 | 1.00e+00 | 2.463 | 1 | 4 | 109 |
GO:0097190 | apoptotic signaling pathway | 1.72e-01 | 1.00e+00 | 2.411 | 1 | 3 | 113 |
GO:0000209 | protein polyubiquitination | 1.76e-01 | 1.00e+00 | 2.373 | 1 | 7 | 116 |
GO:0006006 | glucose metabolic process | 1.79e-01 | 1.00e+00 | 2.348 | 1 | 3 | 118 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.87e-01 | 1.00e+00 | 2.277 | 1 | 3 | 124 |
GO:0009615 | response to virus | 1.90e-01 | 1.00e+00 | 2.254 | 1 | 2 | 126 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.93e-01 | 1.00e+00 | 2.231 | 1 | 3 | 128 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 2.15e-01 | 1.00e+00 | 2.051 | 1 | 3 | 145 |
GO:0034220 | ion transmembrane transport | 2.21e-01 | 1.00e+00 | 2.012 | 1 | 2 | 149 |
GO:0042981 | regulation of apoptotic process | 2.22e-01 | 1.00e+00 | 2.002 | 1 | 7 | 150 |
GO:0010008 | endosome membrane | 2.23e-01 | 1.00e+00 | 1.993 | 1 | 5 | 151 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 2.30e-01 | 1.00e+00 | 1.946 | 1 | 3 | 156 |
GO:0007420 | brain development | 2.44e-01 | 1.00e+00 | 1.847 | 1 | 1 | 167 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 2.45e-01 | 1.00e+00 | 1.839 | 1 | 3 | 168 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 2.65e-01 | 1.00e+00 | 1.708 | 1 | 3 | 184 |
GO:0005794 | Golgi apparatus | 2.70e-01 | 1.00e+00 | 0.978 | 2 | 9 | 610 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 2.72e-01 | 1.00e+00 | 1.669 | 1 | 4 | 189 |
GO:0003924 | GTPase activity | 2.81e-01 | 1.00e+00 | 1.609 | 1 | 7 | 197 |
GO:0006184 | GTP catabolic process | 3.02e-01 | 1.00e+00 | 1.490 | 1 | 7 | 214 |
GO:0019221 | cytokine-mediated signaling pathway | 3.10e-01 | 1.00e+00 | 1.443 | 1 | 2 | 221 |
GO:0030425 | dendrite | 3.20e-01 | 1.00e+00 | 1.386 | 1 | 2 | 230 |
GO:0044281 | small molecule metabolic process | 3.27e-01 | 1.00e+00 | 0.574 | 3 | 15 | 1211 |
GO:0003713 | transcription coactivator activity | 3.28e-01 | 1.00e+00 | 1.342 | 1 | 4 | 237 |
GO:0005975 | carbohydrate metabolic process | 3.46e-01 | 1.00e+00 | 1.248 | 1 | 3 | 253 |
GO:0004842 | ubiquitin-protein transferase activity | 3.48e-01 | 1.00e+00 | 1.237 | 1 | 2 | 255 |
GO:0000166 | nucleotide binding | 3.53e-01 | 1.00e+00 | 1.214 | 1 | 2 | 259 |
GO:0006281 | DNA repair | 3.55e-01 | 1.00e+00 | 1.203 | 1 | 4 | 261 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 3.64e-01 | 1.00e+00 | 1.160 | 1 | 4 | 269 |
GO:0007264 | small GTPase mediated signal transduction | 3.74e-01 | 1.00e+00 | 1.107 | 1 | 7 | 279 |
GO:0005575 | cellular_component | 3.74e-01 | 1.00e+00 | 1.107 | 1 | 1 | 279 |
GO:0016567 | protein ubiquitination | 3.91e-01 | 1.00e+00 | 1.027 | 1 | 3 | 295 |
GO:0005525 | GTP binding | 4.07e-01 | 1.00e+00 | 0.955 | 1 | 7 | 310 |
GO:0007275 | multicellular organismal development | 4.13e-01 | 1.00e+00 | 0.927 | 1 | 1 | 316 |
GO:0019901 | protein kinase binding | 4.14e-01 | 1.00e+00 | 0.923 | 1 | 6 | 317 |
GO:0005813 | centrosome | 4.23e-01 | 1.00e+00 | 0.882 | 1 | 5 | 326 |
GO:0003682 | chromatin binding | 4.24e-01 | 1.00e+00 | 0.878 | 1 | 3 | 327 |
GO:0008283 | cell proliferation | 4.25e-01 | 1.00e+00 | 0.874 | 1 | 4 | 328 |
GO:0015031 | protein transport | 4.37e-01 | 1.00e+00 | 0.817 | 1 | 8 | 341 |
GO:0000139 | Golgi membrane | 4.56e-01 | 1.00e+00 | 0.735 | 1 | 6 | 361 |
GO:0008150 | biological_process | 4.81e-01 | 1.00e+00 | 0.627 | 1 | 3 | 389 |
GO:0045893 | positive regulation of transcription, DNA-templated | 5.55e-01 | 1.00e+00 | 0.330 | 1 | 5 | 478 |
GO:0048471 | perinuclear region of cytoplasm | 5.73e-01 | 1.00e+00 | 0.260 | 1 | 7 | 502 |
GO:0006915 | apoptotic process | 6.10e-01 | 1.00e+00 | 0.115 | 1 | 9 | 555 |
GO:0005783 | endoplasmic reticulum | 6.11e-01 | 1.00e+00 | 0.112 | 1 | 3 | 556 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 6.20e-01 | 1.00e+00 | 0.076 | 1 | 7 | 570 |
GO:0045087 | innate immune response | 6.37e-01 | 1.00e+00 | 0.012 | 1 | 8 | 596 |
GO:0005634 | nucleus | 6.75e-01 | 1.00e+00 | -0.116 | 7 | 43 | 4559 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.41e-01 | 1.00e+00 | -0.393 | 1 | 6 | 789 |
GO:0007165 | signal transduction | 7.90e-01 | 1.00e+00 | -0.594 | 1 | 3 | 907 |
GO:0005615 | extracellular space | 8.08e-01 | 1.00e+00 | -0.671 | 1 | 2 | 957 |
GO:0003677 | DNA binding | 8.80e-01 | 1.00e+00 | -1.019 | 1 | 3 | 1218 |
GO:0005524 | ATP binding | 8.96e-01 | 1.00e+00 | -1.111 | 1 | 15 | 1298 |
GO:0046872 | metal ion binding | 8.98e-01 | 1.00e+00 | -1.121 | 1 | 10 | 1307 |
GO:0006351 | transcription, DNA-templated | 9.21e-01 | 1.00e+00 | -1.267 | 1 | 6 | 1446 |
GO:0005886 | plasma membrane | 9.45e-01 | 1.00e+00 | -1.103 | 2 | 20 | 2582 |