int-snw-6150

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 6.375 3.15e-136 3.60e-07 2.59e-03
tai-screen-luciferase-int-snw-6150 subnetwork

Genes (23)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 10-5.5457.555234--
CHMP2A 27243 10-9.0377.55541YesYes
COPA 1314 32-9.3959.063170YesYes
RPS29 6235 3-8.3866.59729--
RPS24 6229 21-7.0348.389217Yes-
RPAP2 79871 13.1116.37549--
RPS9 6203 18-7.1277.555140Yes-
COPB2 9276 32-13.1689.06341YesYes
RPS4X 6191 18-6.7477.555263Yes-
COPZ1 22818 32-8.3019.06313YesYes
CDC42 998 11-6.9608.389265YesYes
RPS7 6201 1-4.3826.375165Yes-
RPS27A 6233 15-5.6318.389342Yes-
RPS11 6205 17-6.5887.555175Yes-
RPS6 6194 17-5.6038.046208Yes-
SKP1 6500 4-3.7506.413203--
YBX1 4904 1-3.0336.375176--
MAP3K14 9020 1-3.4626.375138-Yes
RPS26 6231 17-7.4788.04660Yes-
ARCN1 372 32-8.2329.063118YesYes
RPS23 6228 3-4.4856.375118Yes-
[ MRPL23 ] 6150 1-2.5716.3759--
RPS13 6207 17-6.5897.555174Yes-

Interactions (61)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
YBX1 4904 RPS7 6201 pp -- int.Intact: MI:0914(association)
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS4X 6191 pp -- int.Intact: MI:0914(association)
YBX1 4904 RPS29 6235 pp -- int.Intact: MI:0914(association)
RPS7 6201 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
RPS4X 6191 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS9 6203 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPAP2 79871 pp -- int.I2D: BioGrid
RPS23 6228 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 SKP1 6500 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
YBX1 4904 RPS24 6229 pp -- int.Intact: MI:0914(association)
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 SKP1 6500 pp -- int.I2D: BioGrid_Yeast, YeastLow
YBX1 4904 RPS8 6202 pp -- int.Intact: MI:0914(association)
YBX1 4904 RPS23 6228 pp -- int.Intact: MI:0914(association)
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS7 6201 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS23 6228 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS23 6228 pp -- int.I2D: YeastLow, BioGrid_Yeast
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS11 6205 pp -- int.Intact: MI:0914(association)
RPS13 6207 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
YBX1 4904 MRPL23 6150 pp -- int.Intact: MI:0914(association)
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS7 6201 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS6 6194 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS24 6229 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS7 6201 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS7 6201 pp -- int.I2D: BioGrid_Yeast

Related GO terms (283)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit3.08e-264.44e-227.592122039
GO:0019058viral life cycle2.80e-224.04e-186.1471323115
GO:0019083viral transcription5.41e-227.80e-186.538122081
GO:0006415translational termination1.35e-211.95e-176.435122087
GO:0003735structural constituent of ribosome3.02e-214.36e-175.8951322137
GO:0006414translational elongation3.16e-214.56e-176.338122093
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.30e-201.88e-166.1771220104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay4.13e-205.95e-166.0451220114
GO:0006413translational initiation2.34e-193.38e-155.8441221131
GO:0006412translation3.05e-184.40e-145.1471323230
GO:0016071mRNA metabolic process1.62e-162.33e-125.0771225223
GO:0016070RNA metabolic process5.58e-168.04e-124.9291225247
GO:0016032viral process4.63e-156.67e-114.0391433534
GO:0015935small ribosomal subunit9.89e-141.43e-097.7906917
GO:0005829cytosol5.65e-138.14e-092.32920612496
GO:0044267cellular protein metabolic process1.35e-121.94e-083.9891223474
GO:0010467gene expression3.06e-124.41e-083.6071329669
GO:0005840ribosome3.10e-104.48e-066.0206858
GO:0044822poly(A) RNA binding9.26e-101.34e-052.94913321056
GO:0016020membrane1.85e-092.66e-052.48415411681
GO:0030126COPI vesicle coat2.41e-093.48e-057.7084712
GO:0048205COPI coating of Golgi vesicle3.48e-095.02e-057.5924813
GO:0030529ribonucleoprotein complex1.74e-082.50e-045.07067112
GO:0005925focal adhesion5.60e-088.07e-043.777819366
GO:0006890retrograde vesicle-mediated transport, Golgi to ER6.08e-088.77e-046.6494825
GO:0061024membrane organization8.16e-081.18e-034.698612145
GO:0042274ribosomal small subunit biogenesis7.72e-071.11e-027.2933612
GO:0070062extracellular vesicular exosome2.19e-063.16e-021.87114402400
GO:0036464cytoplasmic ribonucleoprotein granule5.35e-067.71e-026.4183322
GO:0019843rRNA binding1.01e-051.46e-016.1233427
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.43e-053.50e-017.971235
GO:0033119negative regulation of RNA splicing2.43e-053.50e-017.971225
GO:0006886intracellular protein transport1.42e-041.00e+003.87547171
GO:0006891intra-Golgi vesicle-mediated transport3.26e-041.00e+006.2052417
GO:0006364rRNA processing4.32e-041.00e+004.3233794
GO:0005730nucleolus5.76e-041.00e+001.7829241641
GO:0005844polysome6.03e-041.00e+005.7692223
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway1.48e-031.00e+005.1232336
GO:0022605oogenesis stage1.59e-031.00e+009.293111
GO:0021691cerebellar Purkinje cell layer maturation1.59e-031.00e+009.293111
GO:0000082G1/S transition of mitotic cell cycle1.64e-031.00e+003.65839149
GO:0005737cytoplasm1.91e-031.00e+001.11413433767
GO:0007249I-kappaB kinase/NF-kappaB signaling1.92e-031.00e+004.9352341
GO:0071338positive regulation of hair follicle cell proliferation3.19e-031.00e+008.293112
GO:0060661submandibular salivary gland formation3.19e-031.00e+008.293112
GO:0090135actin filament branching3.19e-031.00e+008.293112
GO:0016197endosomal transport3.68e-031.00e+004.4602357
GO:0031295T cell costimulation4.76e-031.00e+004.2702365
GO:0051683establishment of Golgi localization4.78e-031.00e+007.708123
GO:0034191apolipoprotein A-I receptor binding4.78e-031.00e+007.708113
GO:0003161cardiac conduction system development4.78e-031.00e+007.708113
GO:0051154negative regulation of striated muscle cell differentiation4.78e-031.00e+007.708113
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.50e-031.00e+004.1632870
GO:0003729mRNA binding5.81e-031.00e+004.1232272
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.13e-031.00e+004.0832874
GO:003068690S preribosome6.36e-031.00e+007.293114
GO:0048664neuron fate determination6.36e-031.00e+007.293114
GO:0009301snRNA transcription6.36e-031.00e+007.293114
GO:0070940dephosphorylation of RNA polymerase II C-terminal domain6.36e-031.00e+007.293114
GO:0060684epithelial-mesenchymal cell signaling6.36e-031.00e+007.293114
GO:0051835positive regulation of synapse structural plasticity6.36e-031.00e+007.293114
GO:0031467Cul7-RING ubiquitin ligase complex6.36e-031.00e+007.293114
GO:0072384organelle transport along microtubule6.36e-031.00e+007.293124
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process6.96e-031.00e+003.9892879
GO:0070934CRD-mediated mRNA stabilization7.95e-031.00e+006.971115
GO:0036336dendritic cell migration7.95e-031.00e+006.971115
GO:0035088establishment or maintenance of apical/basal cell polarity7.95e-031.00e+006.971115
GO:1902188positive regulation of viral release from host cell7.95e-031.00e+006.971115
GO:0031256leading edge membrane7.95e-031.00e+006.971115
GO:0008420CTD phosphatase activity7.95e-031.00e+006.971115
GO:0007097nuclear migration9.53e-031.00e+006.708116
GO:0002181cytoplasmic translation9.53e-031.00e+006.708126
GO:0003334keratinocyte development9.53e-031.00e+006.708116
GO:0002309T cell proliferation involved in immune response9.53e-031.00e+006.708116
GO:0045182translation regulator activity9.53e-031.00e+006.708126
GO:0070937CRD-mediated mRNA stability complex9.53e-031.00e+006.708116
GO:0004704NF-kappaB-inducing kinase activity9.53e-031.00e+006.708116
GO:0060789hair follicle placode formation9.53e-031.00e+006.708116
GO:0071204histone pre-mRNA 3'end processing complex9.53e-031.00e+006.708116
GO:0048554positive regulation of metalloenzyme activity9.53e-031.00e+006.708116
GO:0006924activation-induced cell death of T cells9.53e-031.00e+006.708116
GO:0043497regulation of protein heterodimerization activity9.53e-031.00e+006.708116
GO:0050792regulation of viral process9.53e-031.00e+006.708116
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.11e-021.00e+006.485117
GO:0000028ribosomal small subunit assembly1.11e-021.00e+006.485137
GO:0034101erythrocyte homeostasis1.11e-021.00e+006.485117
GO:0051489regulation of filopodium assembly1.11e-021.00e+006.485117
GO:0030157pancreatic juice secretion1.11e-021.00e+006.485117
GO:0039702viral budding via host ESCRT complex1.27e-021.00e+006.293118
GO:0005815microtubule organizing center1.29e-021.00e+003.52423109
GO:0016591DNA-directed RNA polymerase II, holoenzyme1.43e-021.00e+006.123119
GO:0090136epithelial cell-cell adhesion1.43e-021.00e+006.123119
GO:0038061NIK/NF-kappaB signaling1.43e-021.00e+006.123119
GO:0007219Notch signaling pathway1.55e-021.00e+003.38623120
GO:0031274positive regulation of pseudopodium assembly1.58e-021.00e+005.9711210
GO:0032040small-subunit processome1.58e-021.00e+005.9711210
GO:0060047heart contraction1.58e-021.00e+005.9711110
GO:0003723RNA binding1.65e-021.00e+002.46038342
GO:0035518histone H2A monoubiquitination1.74e-021.00e+005.8331111
GO:1903543positive regulation of exosomal secretion1.90e-021.00e+005.7081112
GO:0019082viral protein processing1.90e-021.00e+005.7081212
GO:0000086G2/M transition of mitotic cell cycle1.96e-021.00e+003.20525136
GO:0031929TOR signaling2.05e-021.00e+005.5921113
GO:0032479regulation of type I interferon production2.05e-021.00e+005.5921213
GO:0031333negative regulation of protein complex assembly2.21e-021.00e+005.4851114
GO:0031996thioesterase binding2.21e-021.00e+005.4851114
GO:0030131clathrin adaptor complex2.21e-021.00e+005.4851214
GO:0005762mitochondrial large ribosomal subunit2.21e-021.00e+005.4851114
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.21e-021.00e+003.11323145
GO:0005198structural molecule activity2.36e-021.00e+003.06426150
GO:0048821erythrocyte development2.37e-021.00e+005.3861115
GO:0030225macrophage differentiation2.37e-021.00e+005.3861115
GO:0031369translation initiation factor binding2.37e-021.00e+005.3861115
GO:0051233spindle midzone2.37e-021.00e+005.3861215
GO:0042176regulation of protein catabolic process2.52e-021.00e+005.2931316
GO:0075733intracellular transport of virus2.68e-021.00e+005.2051317
GO:0030742GTP-dependent protein binding2.68e-021.00e+005.2051117
GO:0019068virion assembly2.68e-021.00e+005.2051217
GO:0090316positive regulation of intracellular protein transport2.68e-021.00e+005.2051117
GO:0007088regulation of mitosis2.83e-021.00e+005.1231118
GO:0004709MAP kinase kinase kinase activity2.83e-021.00e+005.1231118
GO:0046847filopodium assembly2.99e-021.00e+005.0451119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.99e-021.00e+005.0451119
GO:0007369gastrulation2.99e-021.00e+005.0451119
GO:0043473pigmentation3.14e-021.00e+004.9711120
GO:0005689U12-type spliceosomal complex3.14e-021.00e+004.9711120
GO:0031435mitogen-activated protein kinase kinase kinase binding3.30e-021.00e+004.9001121
GO:0031424keratinization3.45e-021.00e+004.8331122
GO:0007220Notch receptor processing3.45e-021.00e+004.8331222
GO:1900026positive regulation of substrate adhesion-dependent cell spreading3.61e-021.00e+004.7691123
GO:0007173epidermal growth factor receptor signaling pathway3.61e-021.00e+002.73024189
GO:0002040sprouting angiogenesis3.61e-021.00e+004.7691123
GO:0051017actin filament bundle assembly3.61e-021.00e+004.7691123
GO:0007163establishment or maintenance of cell polarity3.76e-021.00e+004.7081124
GO:0031519PcG protein complex3.91e-021.00e+004.6491125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway3.91e-021.00e+004.6491225
GO:0005978glycogen biosynthetic process4.07e-021.00e+004.5921226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia4.07e-021.00e+004.5921226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity4.07e-021.00e+004.5921226
GO:0045859regulation of protein kinase activity4.07e-021.00e+004.5921126
GO:0051149positive regulation of muscle cell differentiation4.22e-021.00e+004.5381127
GO:0032467positive regulation of cytokinesis4.22e-021.00e+004.5381127
GO:0045184establishment of protein localization4.22e-021.00e+004.5381227
GO:0031069hair follicle morphogenesis4.22e-021.00e+004.5381127
GO:0019005SCF ubiquitin ligase complex4.53e-021.00e+004.4351129
GO:0072686mitotic spindle4.53e-021.00e+004.4351129
GO:0031647regulation of protein stability4.68e-021.00e+004.3861130
GO:0010494cytoplasmic stress granule4.68e-021.00e+004.3861130
GO:0001890placenta development4.83e-021.00e+004.3381131
GO:0007093mitotic cell cycle checkpoint4.83e-021.00e+004.3381131
GO:0032480negative regulation of type I interferon production4.98e-021.00e+004.2931232
GO:0033077T cell differentiation in thymus5.14e-021.00e+004.2481133
GO:0042692muscle cell differentiation5.29e-021.00e+004.2051134
GO:0034332adherens junction organization5.59e-021.00e+004.1231236
GO:0045740positive regulation of DNA replication5.59e-021.00e+004.1231136
GO:0051781positive regulation of cell division6.04e-021.00e+004.0071139
GO:0000166nucleotide binding6.35e-021.00e+002.27622259
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway6.64e-021.00e+003.8661243
GO:0043065positive regulation of apoptotic process6.74e-021.00e+002.22626268
GO:0021762substantia nigra development6.79e-021.00e+003.8331144
GO:0034613cellular protein localization6.79e-021.00e+003.8331244
GO:0045727positive regulation of translation6.79e-021.00e+003.8331144
GO:0008344adult locomotory behavior6.79e-021.00e+003.8331144
GO:0044297cell body7.09e-021.00e+003.7691146
GO:0043525positive regulation of neuron apoptotic process7.09e-021.00e+003.7691246
GO:0007030Golgi organization7.53e-021.00e+003.6781249
GO:0007254JNK cascade7.53e-021.00e+003.6781349
GO:0030175filopodium7.68e-021.00e+003.6491250
GO:0030666endocytic vesicle membrane8.12e-021.00e+003.5651253
GO:0000186activation of MAPKK activity8.27e-021.00e+003.5381154
GO:0051403stress-activated MAPK cascade8.27e-021.00e+003.5381354
GO:0046330positive regulation of JNK cascade8.42e-021.00e+003.5111155
GO:0033138positive regulation of peptidyl-serine phosphorylation9.00e-021.00e+003.4101159
GO:0019901protein kinase binding9.00e-021.00e+001.98426317
GO:0043231intracellular membrane-bounded organelle9.05e-021.00e+001.98025318
GO:0032481positive regulation of type I interferon production9.29e-021.00e+003.3621361
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway9.29e-021.00e+003.3621261
GO:0030141secretory granule9.44e-021.00e+003.3381162
GO:0006417regulation of translation9.44e-021.00e+003.3381262
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest9.73e-021.00e+003.2931664
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle9.87e-021.00e+003.2701665
GO:0071260cellular response to mechanical stimulus9.87e-021.00e+003.2701265
GO:0034166toll-like receptor 10 signaling pathway9.87e-021.00e+003.2701465
GO:0034146toll-like receptor 5 signaling pathway9.87e-021.00e+003.2701465
GO:0035264multicellular organism growth1.02e-011.00e+003.2261167
GO:0003697single-stranded DNA binding1.03e-011.00e+003.2051368
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.07e-011.00e+003.1431471
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.07e-011.00e+003.1431471
GO:0000165MAPK cascade1.09e-011.00e+003.1231172
GO:0034162toll-like receptor 9 signaling pathway1.09e-011.00e+003.1231472
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.09e-011.00e+003.1231672
GO:0034134toll-like receptor 2 signaling pathway1.10e-011.00e+003.1031473
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.12e-011.00e+003.0831274
GO:0060070canonical Wnt signaling pathway1.13e-011.00e+003.0641175
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.13e-011.00e+003.0641675
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.15e-011.00e+003.0451476
GO:0010629negative regulation of gene expression1.16e-011.00e+003.0261277
GO:0031902late endosome membrane1.16e-011.00e+003.0261277
GO:0002756MyD88-independent toll-like receptor signaling pathway1.17e-011.00e+003.0071478
GO:0034138toll-like receptor 3 signaling pathway1.19e-011.00e+002.9891479
GO:0005179hormone activity1.19e-011.00e+002.9891179
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.20e-011.00e+002.9711480
GO:0045177apical part of cell1.22e-011.00e+002.9531181
GO:0008284positive regulation of cell proliferation1.23e-011.00e+001.71527382
GO:0050852T cell receptor signaling pathway1.27e-011.00e+002.8831285
GO:0000278mitotic cell cycle1.28e-011.00e+001.681211391
GO:0003690double-stranded DNA binding1.29e-011.00e+002.8661286
GO:0042593glucose homeostasis1.30e-011.00e+002.8501187
GO:0000187activation of MAPK activity1.34e-011.00e+002.8011290
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.37e-011.00e+002.7691692
GO:0001649osteoblast differentiation1.37e-011.00e+002.7691392
GO:0071456cellular response to hypoxia1.37e-011.00e+002.7691392
GO:0034142toll-like receptor 4 signaling pathway1.42e-011.00e+002.7081496
GO:0043066negative regulation of apoptotic process1.46e-011.00e+001.565213424
GO:0030496midbody1.59e-011.00e+002.53812108
GO:0002224toll-like receptor signaling pathway1.60e-011.00e+002.52414109
GO:0097190apoptotic signaling pathway1.66e-011.00e+002.47213113
GO:0051056regulation of small GTPase mediated signal transduction1.68e-011.00e+002.44714115
GO:0000209protein polyubiquitination1.70e-011.00e+002.43517116
GO:0006006glucose metabolic process1.72e-011.00e+002.41013118
GO:0030036actin cytoskeleton organization1.79e-011.00e+002.35012123
GO:0051092positive regulation of NF-kappaB transcription factor activity1.80e-011.00e+002.33813124
GO:0007179transforming growth factor beta receptor signaling pathway1.86e-011.00e+002.29313128
GO:0005911cell-cell junction1.96e-011.00e+002.20512136
GO:0008286insulin receptor signaling pathway2.04e-011.00e+002.14313142
GO:0010628positive regulation of gene expression2.09e-011.00e+002.10314146
GO:0005515protein binding2.11e-011.00e+000.32112626024
GO:0034220ion transmembrane transport2.13e-011.00e+002.07312149
GO:0042981regulation of apoptotic process2.14e-011.00e+002.06417150
GO:0010008endosome membrane2.15e-011.00e+002.05415151
GO:0008543fibroblast growth factor receptor signaling pathway2.21e-011.00e+002.00713156
GO:0043005neuron projection2.23e-011.00e+001.99816157
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.30e-011.00e+001.13827570
GO:0000398mRNA splicing, via spliceosome2.31e-011.00e+001.93511164
GO:0038095Fc-epsilon receptor signaling pathway2.36e-011.00e+001.90013168
GO:0031965nuclear membrane2.36e-011.00e+001.90011168
GO:0045087innate immune response2.46e-011.00e+001.07328596
GO:0005654nucleoplasm2.46e-011.00e+000.7983151082
GO:0004672protein kinase activity2.47e-011.00e+001.82514177
GO:0019904protein domain specific binding2.50e-011.00e+001.80913179
GO:0006367transcription initiation from RNA polymerase II promoter2.56e-011.00e+001.76913184
GO:0003924GTPase activity2.71e-011.00e+001.67017197
GO:0001701in utero embryonic development2.76e-011.00e+001.64112201
GO:0006184GTP catabolic process2.91e-011.00e+001.55117214
GO:0019221cytokine-mediated signaling pathway2.99e-011.00e+001.50512221
GO:0007067mitotic nuclear division3.06e-011.00e+001.46615227
GO:0008380RNA splicing3.07e-011.00e+001.46013228
GO:0030425dendrite3.09e-011.00e+001.44712230
GO:0043025neuronal cell body3.26e-011.00e+001.35614245
GO:0005975carbohydrate metabolic process3.35e-011.00e+001.31013253
GO:0004842ubiquitin-protein transferase activity3.37e-011.00e+001.29812255
GO:0006281DNA repair3.43e-011.00e+001.26514261
GO:0048011neurotrophin TRK receptor signaling pathway3.52e-011.00e+001.22114269
GO:0007264small GTPase mediated signal transduction3.62e-011.00e+001.16817279
GO:0006955immune response3.71e-011.00e+001.12312288
GO:0016567protein ubiquitination3.79e-011.00e+001.08813295
GO:0005525GTP binding3.94e-011.00e+001.01617310
GO:0007275multicellular organismal development3.99e-011.00e+000.98911316
GO:0007411axon guidance4.02e-011.00e+000.97513319
GO:0015031protein transport4.23e-011.00e+000.87918341
GO:0000139Golgi membrane4.42e-011.00e+000.79716361
GO:0005634nucleus4.48e-011.00e+000.1388434559
GO:0006366transcription from RNA polymerase II promoter4.93e-011.00e+000.58212419
GO:0055085transmembrane transport5.06e-011.00e+000.52813435
GO:0007596blood coagulation5.22e-011.00e+000.46313455
GO:0006468protein phosphorylation5.26e-011.00e+000.44716460
GO:0042802identical protein binding5.44e-011.00e+000.37413484
GO:0048471perinuclear region of cytoplasm5.58e-011.00e+000.32117502
GO:0006915apoptotic process5.95e-011.00e+000.17619555
GO:0005783endoplasmic reticulum5.95e-011.00e+000.17413556
GO:0046872metal ion binding6.30e-011.00e+00-0.0602101307
GO:0005794Golgi apparatus6.30e-011.00e+000.04019610
GO:0003700sequence-specific DNA binding transcription factor activity6.81e-011.00e+00-0.15713699
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.26e-011.00e+00-0.33116789
GO:0005615extracellular space7.94e-011.00e+00-0.61012957
GO:0006355regulation of transcription, DNA-templated8.08e-011.00e+00-0.66913997
GO:0008270zinc ion binding8.08e-011.00e+00-0.66913997
GO:0005739mitochondrion8.08e-011.00e+00-0.67018998
GO:0044281small molecule metabolic process8.67e-011.00e+00-0.9491151211
GO:0003677DNA binding8.69e-011.00e+00-0.958131218
GO:0005524ATP binding8.86e-011.00e+00-1.0501151298
GO:0006351transcription, DNA-templated9.12e-011.00e+00-1.205161446
GO:0005886plasma membrane9.36e-011.00e+00-1.0422202582