reg-snw-7511

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.345	4.95e-08	1.80e-02	1.47e-02

chia-screen-data-Fav-reg-snw-7511 subnetwork

Genes (12)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
EIF2S3	1968	3	-1.940	2.345	13	-	-	-
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
[ XPNPEP1 ]	7511	8	-1.779	2.386	76	TF	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
GUCY1A3	2982	4	-2.148	2.345	19	-	Yes	-
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-

Interactions (14)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
EIF2S3	1968	XPNPEP1	7511	pd	<	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GUCY1A3	2982	XPNPEP1	7511	pd	<	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
EIF2S3	1968	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
XPNPEP1	7511	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	XPNPEP1	7511	pd	<>	reg.ITFP.txt: no annot
XPNPEP1	7511	SYMPK	8189	pd	<>	reg.ITFP.txt: no annot

Related GO terms (128)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005525	GTP binding	7.01e-05	6.84e-01	4.046	4	12	197
GO:0004832	valine-tRNA ligase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0052565	response to defense-related host nitric oxide production	1.23e-03	1.00e+00	9.668	1	1	1
GO:0061383	trabecula morphogenesis	1.23e-03	1.00e+00	9.668	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.23e-03	1.00e+00	9.668	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.23e-03	1.00e+00	9.668	1	1	1
GO:0008175	tRNA methyltransferase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0033688	regulation of osteoblast proliferation	2.46e-03	1.00e+00	8.668	1	1	2
GO:0008074	guanylate cyclase complex, soluble	2.46e-03	1.00e+00	8.668	1	1	2
GO:0010467	gene expression	3.10e-03	1.00e+00	2.605	4	49	535
GO:0070006	metalloaminopeptidase activity	3.68e-03	1.00e+00	8.083	1	1	3
GO:0030828	positive regulation of cGMP biosynthetic process	4.91e-03	1.00e+00	7.668	1	1	4
GO:0010815	bradykinin catabolic process	4.91e-03	1.00e+00	7.668	1	1	4
GO:0036089	cleavage furrow formation	4.91e-03	1.00e+00	7.668	1	1	4
GO:0060087	relaxation of vascular smooth muscle	6.13e-03	1.00e+00	7.347	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.13e-03	1.00e+00	7.347	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	6.13e-03	1.00e+00	7.347	1	2	5
GO:0038027	apolipoprotein A-I-mediated signaling pathway	6.13e-03	1.00e+00	7.347	1	1	5
GO:0043931	ossification involved in bone maturation	6.13e-03	1.00e+00	7.347	1	1	5
GO:0002181	cytoplasmic translation	7.35e-03	1.00e+00	7.083	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	7.35e-03	1.00e+00	7.083	1	2	6
GO:0001055	RNA polymerase II activity	7.35e-03	1.00e+00	7.083	1	3	6
GO:0004383	guanylate cyclase activity	7.35e-03	1.00e+00	7.083	1	1	6
GO:0043297	apical junction assembly	7.35e-03	1.00e+00	7.083	1	1	6
GO:0003924	GTPase activity	8.97e-03	1.00e+00	3.774	2	7	119
GO:0010388	cullin deneddylation	9.79e-03	1.00e+00	6.668	1	4	8
GO:0090307	spindle assembly involved in mitosis	9.79e-03	1.00e+00	6.668	1	2	8
GO:0006450	regulation of translational fidelity	9.79e-03	1.00e+00	6.668	1	1	8
GO:0043296	apical junction complex	9.79e-03	1.00e+00	6.668	1	1	8
GO:0000398	mRNA splicing, via spliceosome	1.03e-02	1.00e+00	3.668	2	15	128
GO:0006184	GTP catabolic process	1.06e-02	1.00e+00	3.646	2	7	130
GO:0005736	DNA-directed RNA polymerase I complex	1.22e-02	1.00e+00	6.347	1	4	10
GO:0001054	RNA polymerase I activity	1.22e-02	1.00e+00	6.347	1	4	10
GO:0005095	GTPase inhibitor activity	1.22e-02	1.00e+00	6.347	1	1	10
GO:0006182	cGMP biosynthetic process	1.22e-02	1.00e+00	6.347	1	1	10
GO:0035307	positive regulation of protein dephosphorylation	1.22e-02	1.00e+00	6.347	1	1	10
GO:0050919	negative chemotaxis	1.22e-02	1.00e+00	6.347	1	1	10
GO:0007263	nitric oxide mediated signal transduction	1.47e-02	1.00e+00	6.083	1	1	12
GO:0005665	DNA-directed RNA polymerase II, core complex	1.59e-02	1.00e+00	5.968	1	3	13
GO:0001056	RNA polymerase III activity	1.59e-02	1.00e+00	5.968	1	3	13
GO:0050772	positive regulation of axonogenesis	1.59e-02	1.00e+00	5.968	1	2	13
GO:0050770	regulation of axonogenesis	1.59e-02	1.00e+00	5.968	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.59e-02	1.00e+00	5.968	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.59e-02	1.00e+00	5.968	1	1	13
GO:0008380	RNA splicing	1.68e-02	1.00e+00	3.302	2	21	165
GO:0006385	transcription elongation from RNA polymerase III promoter	1.71e-02	1.00e+00	5.861	1	3	14
GO:0006386	termination of RNA polymerase III transcription	1.71e-02	1.00e+00	5.861	1	3	14
GO:0050771	negative regulation of axonogenesis	1.71e-02	1.00e+00	5.861	1	2	14
GO:0004177	aminopeptidase activity	1.71e-02	1.00e+00	5.861	1	3	14
GO:0000188	inactivation of MAPK activity	1.83e-02	1.00e+00	5.762	1	1	15
GO:0008135	translation factor activity, nucleic acid binding	1.83e-02	1.00e+00	5.762	1	4	15
GO:0032467	positive regulation of cytokinesis	1.95e-02	1.00e+00	5.668	1	1	16
GO:0017022	myosin binding	1.95e-02	1.00e+00	5.668	1	2	16
GO:0003899	DNA-directed RNA polymerase activity	2.19e-02	1.00e+00	5.499	1	3	18
GO:0006378	mRNA polyadenylation	2.19e-02	1.00e+00	5.499	1	3	18
GO:0005856	cytoskeleton	2.19e-02	1.00e+00	3.099	2	8	190
GO:0036464	cytoplasmic ribonucleoprotein granule	2.31e-02	1.00e+00	5.421	1	1	19
GO:0008180	COP9 signalosome	2.91e-02	1.00e+00	5.083	1	6	24
GO:0006370	7-methylguanosine mRNA capping	2.91e-02	1.00e+00	5.083	1	5	24
GO:0030145	manganese ion binding	3.15e-02	1.00e+00	4.968	1	3	26
GO:0051496	positive regulation of stress fiber assembly	3.15e-02	1.00e+00	4.968	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	3.27e-02	1.00e+00	4.914	1	4	27
GO:0006418	tRNA aminoacylation for protein translation	3.51e-02	1.00e+00	4.810	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	3.51e-02	1.00e+00	4.810	1	6	29
GO:0032154	cleavage furrow	3.63e-02	1.00e+00	4.762	1	3	30
GO:0008015	blood circulation	3.75e-02	1.00e+00	4.714	1	1	31
GO:0021762	substantia nigra development	4.10e-02	1.00e+00	4.581	1	1	34
GO:0007254	JNK cascade	4.10e-02	1.00e+00	4.581	1	1	34
GO:0007266	Rho protein signal transduction	4.22e-02	1.00e+00	4.539	1	2	35
GO:0050434	positive regulation of viral transcription	4.22e-02	1.00e+00	4.539	1	5	35
GO:0030334	regulation of cell migration	4.34e-02	1.00e+00	4.499	1	2	36
GO:0003743	translation initiation factor activity	4.46e-02	1.00e+00	4.459	1	8	37
GO:0006396	RNA processing	4.81e-02	1.00e+00	4.347	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	4.81e-02	1.00e+00	4.347	1	6	40
GO:0008217	regulation of blood pressure	5.04e-02	1.00e+00	4.276	1	2	42
GO:0005829	cytosol	5.20e-02	1.00e+00	1.187	5	88	1787
GO:0032481	positive regulation of type I interferon production	5.74e-02	1.00e+00	4.083	1	3	48
GO:0006368	transcription elongation from RNA polymerase II promoter	6.21e-02	1.00e+00	3.968	1	8	52
GO:0007596	blood coagulation	6.30e-02	1.00e+00	2.263	2	13	339
GO:0045666	positive regulation of neuron differentiation	6.33e-02	1.00e+00	3.941	1	3	53
GO:0006289	nucleotide-excision repair	6.33e-02	1.00e+00	3.941	1	6	53
GO:0071013	catalytic step 2 spliceosome	7.25e-02	1.00e+00	3.738	1	5	61
GO:0005923	tight junction	7.59e-02	1.00e+00	3.668	1	2	64
GO:0005654	nucleoplasm	8.58e-02	1.00e+00	1.479	3	68	876
GO:0030496	midbody	8.62e-02	1.00e+00	3.479	1	6	73
GO:0001649	osteoblast differentiation	8.73e-02	1.00e+00	3.459	1	5	74
GO:0051056	regulation of small GTPase mediated signal transduction	8.95e-02	1.00e+00	3.421	1	2	76
GO:0005938	cell cortex	9.07e-02	1.00e+00	3.402	1	6	77
GO:0016032	viral process	9.46e-02	1.00e+00	1.927	2	30	428
GO:0030529	ribonucleoprotein complex	9.63e-02	1.00e+00	3.311	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	9.74e-02	1.00e+00	3.293	1	2	83
GO:0030027	lamellipodium	1.03e-01	1.00e+00	3.209	1	3	88
GO:0020037	heme binding	1.03e-01	1.00e+00	3.209	1	3	88
GO:0030036	actin cytoskeleton organization	1.05e-01	1.00e+00	3.177	1	4	90
GO:0006413	translational initiation	1.15e-01	1.00e+00	3.039	1	6	99
GO:0007179	transforming growth factor beta receptor signaling pathway	1.24e-01	1.00e+00	2.927	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.25e-01	1.00e+00	2.914	1	2	108
GO:0007049	cell cycle	1.33e-01	1.00e+00	2.823	1	8	115
GO:0004872	receptor activity	1.34e-01	1.00e+00	2.810	1	4	116
GO:0030168	platelet activation	1.60e-01	1.00e+00	2.529	1	5	141
GO:0006367	transcription initiation from RNA polymerase II promoter	1.81e-01	1.00e+00	2.338	1	18	161
GO:0005739	mitochondrion	1.92e-01	1.00e+00	1.304	2	32	659
GO:0007264	small GTPase mediated signal transduction	1.94e-01	1.00e+00	2.225	1	8	174
GO:0006412	translation	1.98e-01	1.00e+00	2.193	1	12	178
GO:0005737	cytoplasm	2.01e-01	1.00e+00	0.628	5	127	2633
GO:0048011	neurotrophin TRK receptor signaling pathway	2.19e-01	1.00e+00	2.032	1	8	199
GO:0006281	DNA repair	2.23e-01	1.00e+00	2.003	1	24	203
GO:0030054	cell junction	2.37e-01	1.00e+00	1.900	1	5	218
GO:0007411	axon guidance	2.55e-01	1.00e+00	1.780	1	8	237
GO:0007155	cell adhesion	2.62e-01	1.00e+00	1.738	1	8	244
GO:0003723	RNA binding	2.65e-01	1.00e+00	1.720	1	22	247
GO:0006508	proteolysis	2.80e-01	1.00e+00	1.624	1	11	264
GO:0005925	focal adhesion	2.97e-01	1.00e+00	1.529	1	14	282
GO:0005524	ATP binding	3.01e-01	1.00e+00	0.868	2	37	892
GO:0009986	cell surface	3.05e-01	1.00e+00	1.484	1	5	291
GO:0070062	extracellular vesicular exosome	3.27e-01	1.00e+00	0.573	3	51	1641
GO:0003677	DNA binding	3.27e-01	1.00e+00	0.781	2	52	947
GO:0006366	transcription from RNA polymerase II promoter	3.47e-01	1.00e+00	1.255	1	23	341
GO:0044267	cellular protein metabolic process	3.56e-01	1.00e+00	1.209	1	14	352
GO:0005515	protein binding	3.95e-01	1.00e+00	0.244	6	198	4124
GO:0042803	protein homodimerization activity	4.16e-01	1.00e+00	0.927	1	13	428
GO:0045087	innate immune response	4.34e-01	1.00e+00	0.848	1	12	452
GO:0016020	membrane	4.47e-01	1.00e+00	0.431	2	56	1207
GO:0007165	signal transduction	5.44e-01	1.00e+00	0.397	1	24	618
GO:0005634	nucleus	6.04e-01	1.00e+00	0.004	4	158	3246
GO:0044822	poly(A) RNA binding	6.41e-01	1.00e+00	0.026	1	45	799
GO:0005886	plasma membrane	6.73e-01	1.00e+00	-0.132	2	46	1784
GO:0005730	nucleolus	7.98e-01	1.00e+00	-0.581	1	74	1217

chia-Fav

reg-snw-7511

Statistics

Genes (12)

Interactions (14)

Related GO terms (128)