reg-snw-5605

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.472	9.42e-09	6.79e-03	6.19e-03

chia-screen-data-Fav-reg-snw-5605 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RBM17	84991	2	-2.439	2.472	22	TF	Yes	Yes
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
SF3A2	8175	3	-1.845	2.472	17	TF	-	-
[ MAP2K2 ]	5605	1	-1.436	2.472	45	-	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
SF3A1	10291	3	-2.787	2.472	8	-	Yes	Yes
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
POLR2E	5434	MAP2K2	5605	pd	>	reg.ITFP.txt: no annot
GPS1	2873	MAP2K2	5605	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
MAP2K2	5605	RBM17	84991	pd	<	reg.ITFP.txt: no annot
SF3A2	8175	SF3A1	10291	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
MAP2K2	5605	SF3A2	8175	pd	<	reg.ITFP.txt: no annot

Related GO terms (132)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000398	mRNA splicing, via spliceosome	1.89e-06	1.85e-02	5.253	4	15	128
GO:0000389	mRNA 3'-splice site recognition	3.52e-06	3.44e-02	9.253	2	2	4
GO:0008380	RNA splicing	5.22e-06	5.10e-02	4.887	4	21	165
GO:0005681	spliceosomal complex	9.28e-06	9.06e-02	6.057	3	8	55
GO:0071013	catalytic step 2 spliceosome	1.27e-05	1.24e-01	5.908	3	5	61
GO:0005654	nucleoplasm	2.55e-04	1.00e+00	2.801	5	68	876
GO:0010467	gene expression	5.23e-04	1.00e+00	3.190	4	49	535
GO:0003723	RNA binding	8.15e-04	1.00e+00	3.890	3	22	247
GO:0005515	protein binding	1.01e-03	1.00e+00	1.244	8	198	4124
GO:0001649	osteoblast differentiation	1.54e-03	1.00e+00	5.044	2	5	74
GO:0005684	U2-type spliceosomal complex	1.64e-03	1.00e+00	9.253	1	2	2
GO:0036289	peptidyl-serine autophosphorylation	2.46e-03	1.00e+00	8.668	1	1	3
GO:0005634	nucleus	2.53e-03	1.00e+00	1.396	7	158	3246
GO:0090170	regulation of Golgi inheritance	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006397	mRNA processing	3.37e-03	1.00e+00	4.472	2	12	110
GO:2000641	regulation of early endosome to late endosome transport	4.09e-03	1.00e+00	7.931	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.09e-03	1.00e+00	7.931	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	4.09e-03	1.00e+00	7.931	1	1	5
GO:0050847	progesterone receptor signaling pathway	4.91e-03	1.00e+00	7.668	1	2	6
GO:0001055	RNA polymerase II activity	4.91e-03	1.00e+00	7.668	1	3	6
GO:0070937	CRD-mediated mRNA stability complex	4.91e-03	1.00e+00	7.668	1	2	6
GO:0032872	regulation of stress-activated MAPK cascade	5.72e-03	1.00e+00	7.446	1	1	7
GO:2000147	positive regulation of cell motility	5.72e-03	1.00e+00	7.446	1	2	7
GO:0000380	alternative mRNA splicing, via spliceosome	5.72e-03	1.00e+00	7.446	1	2	7
GO:0004708	MAP kinase kinase activity	6.54e-03	1.00e+00	7.253	1	2	8
GO:0010944	negative regulation of transcription by competitive promoter binding	6.54e-03	1.00e+00	7.253	1	1	8
GO:0010388	cullin deneddylation	6.54e-03	1.00e+00	7.253	1	4	8
GO:0071354	cellular response to interleukin-6	7.35e-03	1.00e+00	7.083	1	1	9
GO:0005736	DNA-directed RNA polymerase I complex	8.17e-03	1.00e+00	6.931	1	4	10
GO:0005095	GTPase inhibitor activity	8.17e-03	1.00e+00	6.931	1	1	10
GO:0001054	RNA polymerase I activity	8.17e-03	1.00e+00	6.931	1	4	10
GO:0060766	negative regulation of androgen receptor signaling pathway	8.98e-03	1.00e+00	6.794	1	4	11
GO:0043539	protein serine/threonine kinase activator activity	9.79e-03	1.00e+00	6.668	1	1	12
GO:0005666	DNA-directed RNA polymerase III complex	1.06e-02	1.00e+00	6.553	1	3	13
GO:0005665	DNA-directed RNA polymerase II, core complex	1.06e-02	1.00e+00	6.553	1	3	13
GO:0001056	RNA polymerase III activity	1.06e-02	1.00e+00	6.553	1	3	13
GO:0006386	termination of RNA polymerase III transcription	1.14e-02	1.00e+00	6.446	1	3	14
GO:0006385	transcription elongation from RNA polymerase III promoter	1.14e-02	1.00e+00	6.446	1	3	14
GO:0070371	ERK1 and ERK2 cascade	1.14e-02	1.00e+00	6.446	1	1	14
GO:0016575	histone deacetylation	1.14e-02	1.00e+00	6.446	1	2	14
GO:0000188	inactivation of MAPK activity	1.22e-02	1.00e+00	6.347	1	1	15
GO:0004712	protein serine/threonine/tyrosine kinase activity	1.38e-02	1.00e+00	6.166	1	2	17
GO:0030532	small nuclear ribonucleoprotein complex	1.38e-02	1.00e+00	6.166	1	1	17
GO:0003899	DNA-directed RNA polymerase activity	1.47e-02	1.00e+00	6.083	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	1.55e-02	1.00e+00	6.005	1	1	19
GO:0071902	positive regulation of protein serine/threonine kinase activity	1.63e-02	1.00e+00	5.931	1	2	20
GO:0032947	protein complex scaffold	1.63e-02	1.00e+00	5.931	1	2	20
GO:0071897	DNA biosynthetic process	1.63e-02	1.00e+00	5.931	1	2	20
GO:0006370	7-methylguanosine mRNA capping	1.95e-02	1.00e+00	5.668	1	5	24
GO:0008180	COP9 signalosome	1.95e-02	1.00e+00	5.668	1	6	24
GO:0097110	scaffold protein binding	2.03e-02	1.00e+00	5.610	1	1	25
GO:0006360	transcription from RNA polymerase I promoter	2.19e-02	1.00e+00	5.499	1	4	27
GO:0044822	poly(A) RNA binding	2.24e-02	1.00e+00	2.196	3	45	799
GO:0009898	cytoplasmic side of plasma membrane	2.27e-02	1.00e+00	5.446	1	3	28
GO:0006383	transcription from RNA polymerase III promoter	2.35e-02	1.00e+00	5.395	1	6	29
GO:0005778	peroxisomal membrane	2.35e-02	1.00e+00	5.395	1	3	29
GO:0007254	JNK cascade	2.75e-02	1.00e+00	5.166	1	1	34
GO:0050434	positive regulation of viral transcription	2.83e-02	1.00e+00	5.124	1	5	35
GO:0006396	RNA processing	3.23e-02	1.00e+00	4.931	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	3.23e-02	1.00e+00	4.931	1	6	40
GO:0000186	activation of MAPKK activity	3.31e-02	1.00e+00	4.896	1	1	41
GO:0051403	stress-activated MAPK cascade	3.39e-02	1.00e+00	4.861	1	2	42
GO:0032481	positive regulation of type I interferon production	3.87e-02	1.00e+00	4.668	1	3	48
GO:0034146	toll-like receptor 5 signaling pathway	4.03e-02	1.00e+00	4.610	1	3	50
GO:0034166	toll-like receptor 10 signaling pathway	4.03e-02	1.00e+00	4.610	1	3	50
GO:0006368	transcription elongation from RNA polymerase II promoter	4.18e-02	1.00e+00	4.553	1	8	52
GO:0030165	PDZ domain binding	4.18e-02	1.00e+00	4.553	1	3	52
GO:0006289	nucleotide-excision repair	4.26e-02	1.00e+00	4.525	1	6	53
GO:0005770	late endosome	4.34e-02	1.00e+00	4.499	1	2	54
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	4.42e-02	1.00e+00	4.472	1	3	55
GO:0034162	toll-like receptor 9 signaling pathway	4.42e-02	1.00e+00	4.472	1	3	55
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	4.42e-02	1.00e+00	4.472	1	3	55
GO:0004713	protein tyrosine kinase activity	4.42e-02	1.00e+00	4.472	1	1	55
GO:0034134	toll-like receptor 2 signaling pathway	4.50e-02	1.00e+00	4.446	1	3	56
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	4.58e-02	1.00e+00	4.421	1	2	57
GO:0042826	histone deacetylase binding	4.66e-02	1.00e+00	4.395	1	5	58
GO:0000165	MAPK cascade	4.66e-02	1.00e+00	4.395	1	3	58
GO:0002756	MyD88-independent toll-like receptor signaling pathway	4.66e-02	1.00e+00	4.395	1	2	58
GO:0034138	toll-like receptor 3 signaling pathway	4.73e-02	1.00e+00	4.371	1	2	59
GO:0007265	Ras protein signal transduction	4.73e-02	1.00e+00	4.371	1	3	59
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	4.89e-02	1.00e+00	4.323	1	4	61
GO:0045087	innate immune response	4.97e-02	1.00e+00	2.433	2	12	452
GO:0000187	activation of MAPK activity	5.05e-02	1.00e+00	4.276	1	3	63
GO:0030308	negative regulation of cell growth	5.59e-02	1.00e+00	4.124	1	3	70
GO:0034142	toll-like receptor 4 signaling pathway	5.83e-02	1.00e+00	4.064	1	3	73
GO:0005938	cell cortex	6.14e-02	1.00e+00	3.987	1	6	77
GO:0030529	ribonucleoprotein complex	6.53e-02	1.00e+00	3.896	1	5	82
GO:0002224	toll-like receptor signaling pathway	6.60e-02	1.00e+00	3.878	1	3	83
GO:0018108	peptidyl-tyrosine phosphorylation	7.07e-02	1.00e+00	3.778	1	2	89
GO:0008286	insulin receptor signaling pathway	7.68e-02	1.00e+00	3.653	1	2	97
GO:0005911	cell-cell junction	8.21e-02	1.00e+00	3.553	1	3	104
GO:0005769	early endosome	8.59e-02	1.00e+00	3.485	1	3	109
GO:0042981	regulation of apoptotic process	8.82e-02	1.00e+00	3.446	1	4	112
GO:0008543	fibroblast growth factor receptor signaling pathway	8.97e-02	1.00e+00	3.421	1	2	114
GO:0007049	cell cycle	9.05e-02	1.00e+00	3.408	1	8	115
GO:0005739	mitochondrion	9.71e-02	1.00e+00	1.889	2	32	659
GO:0038095	Fc-epsilon receptor signaling pathway	1.03e-01	1.00e+00	3.209	1	2	132
GO:0007173	epidermal growth factor receptor signaling pathway	1.11e-01	1.00e+00	3.104	1	5	142
GO:0044212	transcription regulatory region DNA binding	1.11e-01	1.00e+00	3.094	1	13	143
GO:0006367	transcription initiation from RNA polymerase II promoter	1.25e-01	1.00e+00	2.922	1	18	161
GO:0005874	microtubule	1.26e-01	1.00e+00	2.905	1	10	163
GO:0007264	small GTPase mediated signal transduction	1.34e-01	1.00e+00	2.810	1	8	174
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.794	1	13	176
GO:0005737	cytoplasm	1.43e-01	1.00e+00	0.891	4	127	2633
GO:0005743	mitochondrial inner membrane	1.50e-01	1.00e+00	2.631	1	9	197
GO:0004674	protein serine/threonine kinase activity	1.50e-01	1.00e+00	2.631	1	8	197
GO:0048011	neurotrophin TRK receptor signaling pathway	1.52e-01	1.00e+00	2.617	1	8	199
GO:0006281	DNA repair	1.55e-01	1.00e+00	2.588	1	24	203
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.539	1	7	210
GO:0005524	ATP binding	1.61e-01	1.00e+00	1.453	2	37	892
GO:0003677	DNA binding	1.78e-01	1.00e+00	1.366	2	52	947
GO:0007411	axon guidance	1.79e-01	1.00e+00	2.365	1	8	237
GO:0008285	negative regulation of cell proliferation	2.06e-01	1.00e+00	2.140	1	11	277
GO:0005925	focal adhesion	2.09e-01	1.00e+00	2.114	1	14	282
GO:0009986	cell surface	2.15e-01	1.00e+00	2.069	1	5	291
GO:0045892	negative regulation of transcription, DNA-templated	2.32e-01	1.00e+00	1.945	1	17	317
GO:0006366	transcription from RNA polymerase II promoter	2.48e-01	1.00e+00	1.840	1	23	341
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	11	344
GO:0016020	membrane	2.59e-01	1.00e+00	1.016	2	56	1207
GO:0005730	nucleolus	2.63e-01	1.00e+00	1.004	2	74	1217
GO:0045893	positive regulation of transcription, DNA-templated	2.70e-01	1.00e+00	1.695	1	21	377
GO:0005783	endoplasmic reticulum	2.73e-01	1.00e+00	1.680	1	12	381
GO:0005794	Golgi apparatus	2.94e-01	1.00e+00	1.556	1	6	415
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	30	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	29	456
GO:0005887	integral component of plasma membrane	3.85e-01	1.00e+00	1.086	1	8	575
GO:0007165	signal transduction	4.07e-01	1.00e+00	0.982	1	24	618
GO:0005576	extracellular region	4.30e-01	1.00e+00	0.881	1	15	663
GO:0005829	cytosol	4.46e-01	1.00e+00	0.450	2	88	1787
GO:0006355	regulation of transcription, DNA-templated	4.56e-01	1.00e+00	0.772	1	31	715
GO:0008270	zinc ion binding	4.62e-01	1.00e+00	0.748	1	39	727
GO:0070062	extracellular vesicular exosome	7.71e-01	1.00e+00	-0.427	1	51	1641

chia-Fav

reg-snw-5605

Statistics

Genes (8)

Interactions (7)

Related GO terms (132)